1,000 results on '"Mater, Domini"'
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2. Immune Checkpoints in COPD (CP-COPD)
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Azienda Sanitaria Provinciale Di Catanzaro, Azienda Ospedaliera Universitaria Mater Domini, Catanzaro, and Luca Gallelli, Principal Investigator, Clinical Professor
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- 2022
3. Biomarkers for Identification of COVID-19 Infection (B-DT-COV2)
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Azienda Ospedaliera Pugliese Ciaccio, Azienda Ospedaliera Universitaria Mater Domini, Catanzaro, and Luca Gallelli, Clinical Professor
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- 2021
4. Effectiveness of Liposomial Ozonized-Oil for Cataract Surgery
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Azienda Policlinico Umberto I, Roma, Università degli Studi del Molise, Clinica Oculistica, Clinica Mediterranea, Napoli, Ospedale Santa Croce-Carle Cuneo, Centro Medico Oculistico ALSO, Saronno, Fondazione G.B. Bietti, IRCCS , Roma, Ospedale San Carlo di Nancy, Roma, Centro oftalmologico LASERVISTA, Caserta, Casa di cura GEPOS, Telese, Azienda Ospedaliero-Universitaria Consorziale, Bari, Ospedale generale regionale F. Miulli, Acquaviva delle Fonti, Azienda Ospedaliera Universitaria Mater Domini, Catanzaro, Ospedale Policlinico Casilino, Roma, Ospedale G. Panico, Tricase, Studio oculistico Laborante, Studio oculistico Franchini, U.C.O Ospedali Civico di Cristina Benfratelli, and A.O.U. Città della Salute e della Scienza - Molinette Hospital
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- 2021
5. Gender Differences and SNPs in Asthmatic Patients
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Azienda Sanitaria Provinciale Di Catanzaro, Azienda Ospedaliera Universitaria Mater Domini, Catanzaro, and Luca Gallelli, MD PhD
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- 2020
6. Escin in Patients With Covid-19 Infection (add-on-COV2)
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Azienda Ospedaliera Pugliese Ciaccio, Azienda Ospedaliera Universitaria Mater Domini, Catanzaro, and Luca Gallelli, Clinical Professor
- Published
- 2020
7. Macroscopic on Site Evaluation (MOLSE) vs Standard Specimen Acquisition of Solid Lesions During EUS-FNB (MOSE)
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Humanitas Mater Domini
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- 2020
8. Hyperimmune Plasma in Patients With COVID-19 Severe Infection (COV2-CP)
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Azienda Ospedaliera Universitaria Mater Domini, Catanzaro, Azienda Sanitaria Provinciale Di Catanzaro, Annunziata Hospital, Cosenza, Italy, Azienda Ospedaliera Bianchi-Melacrino-Morelli, and Luca Gallelli, MD
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- 2020
9. High Flow Nasal Therapy Versus Noninvasive Ventilation in COPD Exacerbation
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Azienda Ospedaliera Universitaria Mater Domini, Catanzaro and Andrea Cortegiani, MD, Principal Investigator
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- 2020
10. 'High Levels of EMT-TFs for the Diagnosis of Colorectal Cancer (CRC)'
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Cliniche Gavazzeni spa - Bergamo (BG), Istituto Clinico Mater Domini - Castellanza (VA), and Humanitas Gradenigo - Torino
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- 2020
11. The Role of Registers in Increasing Knowledge and Improving Management of Children and Adolescents Affected by Familial Hypercholesterolemia: the LIPIGEN Pediatric Group
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Gazzotti, Marta, Casula, Manuela, Bertolini, Stefano, Capra, Maria Elena, Olmastroni, Elena, Catapano, Alberico Luigi, Pederiva, Cristina, and the LIPIGEN Pediatric Group: Massimiliano Allevi, Internal Medicine and Geriatrics, Department of Clinical and Molecular Sciences, University 'Politecnica delle Marche' and IRCCS-INRCA, Ancona, Italy, Marcello, Arca, Dipartimento di Medicina Traslazionale, e di Precisione, O Policlinico Umberto I, Sapienza Università di Roma—A. U., Rome, Italy, Renata, Auricchio, Dipartimento di Scienze Mediche Traslazionali, AOU Policlinico Federico II, Naples, Italy, Averna, Maurizio, Dipartimento di Promozione della Salute, Materno-Infantile, di Medicina Interna, e Specialistica di Eccellenza, Università degli Studi di Palermo, Palermo, Italy, Davide, Baldera, Dipartimento di Scienze Biomediche, Università degli Studi di Cagliari and Centro per le Malattie Dismetaboliche, e l’Arteriosclerosi, Onlus Cagliari, Associazione ME. DI. CO., Cagliari, Italy, Giuseppe, Banderali, Clinica Pediatrica, U. O., Servizio Clinico Dislipidemie per lo Studio, e la Prevenzione dell’Aterosclerosi in età Pediatrica, ASSTSanti Paolo, e Carlo, Milan, Italy, Andrea, Bartuli, UOC Malattie Rare, e Genetica Medica, Ospedale Pediatrico Bambino Gesù, Irccs, Rome, Italy, Stefano, Bertolini, Department of Internal Medicine, University of Genova, Genova, Italy, Giacomo, Biasucci, Centro Dislipidemie in Età Evolutiva, Pediatria e Neonatologia, U. O., Ospedale Guglielmo da Saliceto, Piacenza, Italy, Claudio, Borghi, di Medicina Interna Cardiovascolare, U. O., Centro, Aterosclerosi, Ambulatorio, Dislipidemie, Orsola-Malpighi, IRCCS S. Orsola Ospedale Policlinico S., Bologna, Italy, Patrizia, Bruzzi, Pediatria, U. O. C., Azienda Ospedaliero Universitaria di Modena, Modena, Italy, Raffaele, Buganza, Paediatric, Endocrinology, Department of Public Health and Paediatric Sciences, Turin, University, Turin, Italy, Paola Sabrina Buonuomo, Paolo, Calabrò, U. O. C. Cardiologia Clinica a Direzione Universitaria e U. T. I. C., 'Sant’Anna e San Sebastiano', A. O. R. N., Italy and Dipartimento di Scienze Mediche Traslazionali, Università degli Studi della Campania, Sebastiano, Calandra, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Maria Elena Capra, Francesca, Carubbi, Medicina interna metabolica, U. O., Centro dislipidemie, e malattie metaboliche rare, Ospedale Civile Baggiovara, AOU di Modena, Manuela, Casula, Dipartimento di Scienze Farmacologiche, e Biomolecolari, Università degli Studi di Milano, and IRCCS MultiMedica, Sesto San Giovanni (Milan), Alberico Luigi Catapano, Arturo, Cesaro, Università degli Studi della Campania 'Luigi Vanvitelli', Francesco, Cipollone, Clinica, Medica, Centro di riferimento regionale per le Dislipidemie, Annunziata, Ospedale Policlinico S. S., Chieti, Italy, Nadia, Citroni, Centro Dislipidemie, e Aterosclerosi, UOC Medicina Interna, Ospedale di Trento, Trento, Italy, Giuseppe, Covetti, Medicina Interna 2, U. O., Centro per le malattie da arteriosclerosi, Aorn, Cardarelli, Annalaura, Cremonini, IRCCS Ospedale policlinico San Martino UOSD Dietetica, e Nutrizione Clinica and Dipartimento di Medicina Interna, Università di Genova, Sergio, D’Addato, Maria Del Ben, Dipartimento Scienze Cliniche, Internistiche, Anestesiologiche e Cardiovascolari, - Sapienza Università, Policlinico Umberto I, A. O., Maria Donata Di Taranto, Dipartimento di Medicina Molecolare, e Biotecnologie Mediche, Università degli studi di Napoli Federico II and CEINGE Biotecnologie Avanzate, s. c. a. r. l., Giuliana, Fortunato, Roberto, Franceschi, Uoc, Pediatria, Federica, Galimberti, Irccs, Multimedica, Marta, Gazzotti, Fondazione SISA (Società Italiana per lo Studio dell’Aterosclerosi), Simonetta, Genovesi, IRCCS Istituto Auxologico Italiano and Dipartimento di Medicina, e Chirurgia, Università di Milano- Bicocca, Antonina, Giammanco, Liliana, Grigore, Centro per lo Studio dell’Aterosclerosi, Italy and Centro per lo Studio dell’Aterosclerosi, Bassini, Ospedale E., Cinisello, Balsamo, Ornella, Guardamagna, Arcangelo, Iannuzzi, Gabriella, Iannuzzo, Dipartimento di Medicina Clinica, e Chirurgia, Centro Coordinamento regionale per le Iperlipidemie, Lidia Lascala, AOU Mater Domini, Fabiana, Locatelli, Ambulatorio ipertensione dislipidemie rischio cardiovascolare, ASST Valle Olona, Ospedale di Gallarate, Gallarate, Italy, Ospedale di Busto Arsizio, Busto, Arsizio, Lorenzo, Iughetti, Sara, Madaghiele, Frugoni' and Centro di Assistenza e Ricerca Malattie Rare, U. O. di Medicina Interna e Geriatria 'C., Universitaria Policlinico Consorziale, A. O., Università degli Studi di Bari 'Aldo Moro', Bari, Italy, Giuseppe, Mandraffino, Martino, Department of Clinical and Experimental Medicine—Lipid Center—University Hospital G., Messina, Italy, Massimo Raffaele Mannarino, Internal, Medicine, University of Perugia, Angiology and Arteriosclerosis Diseases. Department of Medicine and Surgery., Perugia, Italy, Bucci, Marco, Lorenzo, Maroni, Ilenia, Minicocci, Giuliana, Mombelli, Centro Dislipidemie ASST Grande Ospedale Metropolitano Niguarda, Sandro, Muntoni, Fabio, Nascimbeni, Elena, Olmastroni, Servizio di Epidemiologia, e Farmacologia Preventiva (SEFAP), Dipartimento di Science Farmacologiche, e Biomolecolari, Gianfranco, Parati, Università di Milano-Bicocca, Angelina, Passaro, Department of Translational Medicine, University of Ferrara, Italy and Research and Innovation Section, University Hospital of Ferrara Arcispedale Sant’Anna, Chiara, Pavanello, Milan, Italy and Centro Grossi Paoletti, Milano, Italy, Cristina, Pederiva, ASST-Santi Paolo, e Carlo, Fabio, Pellegatta, Francesco Massimo Perla, Dipartimento Materno Infantile, e Scienze Urologiche—Sapienza Università, Medicina, Generale, Ospedale di Trecenta, Trecenta, Rovigo, Matteo, Pirro, Livia, Pisciotta, Arturo, Pujia, Mater Domini, A. O. U., UOC di Nutrizione Clinica, Purrello, Francesco, Department of Clinical and Experimental Medicine, University of Catania, Ospedale, Garibaldi, Catania, Italy, Elisabetta, Rinaldi, Endocrinologia, U. O., Diabetologia, e Malattie del Metabolismo, Universitaria Integrata di Verona, Centro regionale specializzato per la diagnosi e terapia delle dislipidemie e aferesi terapeutica and A. O., Verona, Italy, Riccardo, Sarzani, Scicali, Roberto, Patrizia, Suppressa, Patrizia, Tarugi, Department of Life Sciences, Sabrina, Verachtert, Giovanni Battista Vigna, Josè Pablo Werba, Ambulatorio Prevenzione Aterosclerosi, U. O., IRCCS Centro Cardiologico Monzino, Alberto, Zambon, Dipartimento di Medicina, Università di Padova, Padua, Italy, Sabina, Zambon, Maria Grazia Zenti, Servizio di Diabetologia, e Malattie Metaboliche, Pederzoli, Ospedale P., Peschiera del Garda, and Verona, Italy.
- Subjects
genetic diagnosis ,clinical diagnosis ,familial hypercholesterolemia ,cardiovascular genetics ,pathology register ,pediatric cohort ,Settore BIO/14 - Farmacologia ,Genetics ,Molecular Medicine ,Genetics (clinical) - Abstract
Pathology registers can be a useful tool to overcome obstacles in the identification and management of familial hypercholesterolemia since childhood. In 2018, the LIPIGEN pediatric group was constituted within the Italian LIPIGEN study to focus on FH subjects under 18 years. This work aimed at discussing its recent progress and early outcomes. Demographic, biochemical, and genetic baseline characteristics were collected, with an in-depth analysis of the genetic defects. The analysis was carried out on 1,602 children and adolescents (mean age at baseline 9.9 ± 4.0 years), and almost the whole cohort underwent the genetic test (93.3%). Overall, the untreated mean value of LDL-C was 220.0 ± 97.2 mg/dl, with an increasing gradient from subjects with a negative (N = 317; mean untreated LDL-C = 159.9 ± 47.7 mg/dl), inconclusive (N = 125; mean untreated LDL-C = 166.4 ± 56.5 mg/dl), or positive (N = 1,053; mean untreated LDL-C = 246.5 ± 102.1 mg/dl) genetic diagnosis of FH. In the latter group, the LDL-C values presented a great variability based on the number and the biological impact of involved causative variants. The LIPIGEN pediatric group represents one of the largest cohorts of children with FH, allowing the deepening of the characterization of their baseline and genetic features, providing the basis for further longitudinal investigations for complete details.
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- 2022
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12. Clinical features and outcomes of elderly hospitalised patients with chronic obstructive pulmonary disease, heart failure or both
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Crisafulli, Ernesto, Sartori, Giulia, Vianello, Alice, Busti, Fabiana, Nobili, Alessandro, Mannucci, Pier Mannuccio, Girelli, Domenico Investigators—Domenico Prisco, Elena, Silvestri, Giacomo, Emmi, Alessandra, Bettiol, Irene Mattioli (Azienda Ospedaliero Universitaria Careggi Firenze, SOD Medicina Interna Interdisciplinare), Gianni, Biolo, Michela, Zanetti, Giacomo, Bartelloni, Michele, Zaccari, Massi- miliano Chiuch (Azienda Sanitaria Universitaria Integrata di Trieste, Clinica Medica Generale, e Terapia Medica), Massimo, Vanoli, Giulia, Grignani, Edoardo Alessandro Pulixi (Azienda Ospedaliera della Pro- vincia di Lecco, Ospedale di Merate, Lecco, Medicina, Interna), Matteo, Pirro, Graziana, Lupattelli, Vanessa, Bianconi, Riccardo, Alcidi, Alessia, Giotta, Mannarino (Azienda Ospedaliera Santa Maria della Misericordia, Massimo R., Perugia, Medicina, Interna, Angiologia Malattie da Arteriosclerosi), Domenico, Girelli, Fabiana, Busti, Giacomo Marchi (Azienda Ospedaliera Universitaria Integrata di Verona, Verona, Medicina Generale e Malattie Aterotrombotiche, e Degenerative), Mario, Barbagallo, Ligia, Dominguez, Vincenza, Beneduce, Federica Cacioppo (Azienda Ospedaliera Universitaria Policlinico Giaccone Policlinico di Palermo, Palermo, Unità Operativa di Geriatria, e Lun- godegenza), Salvatore, Corrao, Giuseppe, Natoli, Salvatore, Mularo, Massimo, Raspanti, Christiano, Argano, Civico, Federica Cavallaro (A. R. N. A. S., Cristina, Di, Benfratelli, Palermo, UOC Medicina Interna ad Indirizzo Geriatrico- Riabilitativo), Marco, Zoli, Maria Laura Mata- cena, Giuseppe, Orio, Eleonora, Magnolfi, Giovanni, Serafini, Angelo, Simili, Mattia, Brunori, Ilaria, Lazzari, Orsola-Malpighi, Angelo Simili (Azienda Ospe- daliera Universitaria Policlinico S., Bologna, Unità Operativa di Medicina Interna Zoli), Maria Domenica Cappellini, Gio- vanna Fabio, Margherita Migone De Amicis, Giacomo De Luca, Nata- lia Scaramellini, Valeria Di Stefano, Simona, Leoni, Sonia, Seghezzi, Alessandra Danuto Di Mauro, Diletta, Maira, Marta Mancarella (Fon- dazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milano, Unità Operativa Medicina Interna IA), Tiziano, Lucchi, Paolo Dionigi Rossi, Marta, Clerici, Alessandra Danuta Di Mauro, Giulia, Bonini, Federica, Conti, Silvia, Prolo, Maddalena, Fabrizi, Miriana, Martelengo, Giulia, Vigani, Paola Nicolini (Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milano, Geriatria), Antonio Di Sabatino, Emanuela, Miceli, Marco Vincenzo Lenti, Martina, Pisati, Lavinia, Pitotti, Donatella, Padula, Valentina, Antoci, Ginevra Cambiè (IRCCS Policlinico San Matteo di Pavia, Pavia, Clinica Medica, I, Reparto, 11), Roberto, Pontremoli, Valentina, Beccati, Giulia, Nobili, Giovanna, Leoncini, Jacopo, Alberto, Federico Cattaneo (IRCCS Azienda Ospedaliera Universitaria San Martino-IST di Genova, Gen-, Ova, Clinica di Medicina Interna 2), Luigi, Anastasio, Lucia, Sofia, Maria Carbone (Ospedale Civile Jazzolino di Vibo Valentia, Vibo Val- entia, Medicina, Generale), Francesco, Cipollone, Maria Teresa Guag- nano, Ilaria, Rossi, Emanuele, Valeriani, Damiani, D’Ardes, Lucia, Esposito, Simona, Sestili, Annunziata, Ermanno Angelucci (Ospedale Clinicizzato SS., Chieti, Clinica, Medica), Gerardo, Mancuso, Daniela, Calipari, Mosè Bartone (Ospedale Giovanni Paolo II Lamezia Terme, Catanzaro, Unità Operativa Complessa Medicina Interna), Giuseppe, Delitala, Maria, Berria, Alessandro Delitala (Azienda ospedaliera- universitaria di Sassari, Maurizio, Muscaritoli, Ales- sio Molfino, Enrico, Petrillo, Antonella, Giorgi, Christian, Gracin, Gio- vanni Imbimbo (Policlinico Umberto, I, Sapienza Università di Roma, Medicina Interna, e Nutrizione Clinica Policlinico Umberto I), Giuseppe, Zuccalà, Gemelli, Gabriella D’Aurizio (Policlinico Universitario A., Roma, Roma, Unità Operativa Complessa Medicina d'Urgenza, e Pronto Soccorso)Giuseppe Romanelli, Alessandra, Marengoni, Andrea, Volpini, Daniela, Lucente, Francesca, Manzoni, Annalisa, Pirozzi, Alberto Zucchelli (Unità Operativa Complessa di Medicina I, a indirizzo geriatrico, Spedali, Civili, Montichiari, Brescia), Antonio, Picardi, Umberto Vespasiani Gentilucci, Paolo, Gallo, Chiara Dell’Unto (Università Campus Bio- Medico, Roma, Medicina Clinica-Epatolo- gia), Giuseppe, Bellelli, Maurizio, Corsi, Cesare, Antonucci, Chiara, Sidoli, Giulia, Principato, Alessandra, Bonfanti, Hajnalka, Szabo, Paolo, Mazzola, Andrea, Piazzoli, Gerardo, Maurizio Corsi (Università degli studi di Milano-Bicocca Ospedale S., Monza, Unità Operativa di Geri- atria), Franco, Arturi, Elena, Succurro, Bruno, Tassone, Federica Giofrè (Università degli Studi Magna Grecia, Policlinico Mater Domini, Cat-, Anzaro, Unità Operativa Complessa di Medicina Interna), Maria Grazia Serra, Maria Antonietta Bleve (Azienda Ospedaliera, Lecce, Unità Operativa Complessa Medicina), Antonio, Brucato, Teresa De Falco, Enrica, Negro, Martino, Brenna, Lucia, Trotta, Giovanni Lorenzo Squintani (ASST FatebenefratelliSacco, Maria Luisa Randi, Fabrizio, Fabris, Irene, Bertozzi, Giulia, Bogoni, Maria Victoria Rabuini, Tancredi, Prandini, Francesco, Ratti, Chiara, Zurlo, Lorenzo, Cerruti, Elisabetta Cosi (Azienda Ospe- daliera Università di Padova, Padova, Clinica Medica I), Roberto Man- fredini, Benedetta, Boari, Alfredo De Giorgi, Ruana, Tiseo, Giulia Marta Viglione, Caterina Savriè (Azienda OspedalieraUniversitaria Sant'Anna, Ferrara, Unità Operativa Clinica Medica), Giuseppe, Paolisso, Maria Rosaria Rizzo, Claudia, Catalano, Irene Di Meo (Azienda Ospedaliera Universitaria della Seconda Università degli Studi di Napoli, Napoli, VI Divisione di Medicina Interna, e Malattie Nutrizionali dell'Invecchiamento), Claudio, Borghi, Enrico, Strocchi, Eugenia, Ianniello, Mario, Soldati, Silvia, Schiavone, Alessio, Bragagni, 13 Francesca Giulia Leoni, Valeria De Sando, Sara, Scarduelli, Michela, Cammarosano, Orsola-Malpighi, Ilenia Pareo (Azienda Ospedaliera Universitaria Poli- clinico S., Unità Operativa di Medicina Interna Borghi), Carlo, Sabbà, Francesco Saverio Vella, Patrizia Sup- pressa, Giovanni Michele De Vincenzo, Alessio, Comitangelo, Ema- nuele Amoruso, Carlo, Custodero, Giuseppe, Re, Andrea, Schilardi, Francesca Loparco (Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari, Bari, Frugoni), Medicina Interna Universitaria C., Luigi, Fenoglio, Andrea, Falcetta, Alessia Valentina Giraudo, Salvatore D’Aniano (Azienda Sanitaria Ospedaliera Santa Croce, e Carle di Cuneo, Cuneo, Ademe, Medicina Interna), S. C., Fracanzani, Anna L., Silvia, Tiraboschi, Annalisa, Cespiati, Giovanna, Oberti, Giordano, Sigon, Felice Cinque (Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, UOC Medicina Generale ad Indirizzo Metabolico), Flora, Peyvandi, Raffaella, Rossio, Colombo, Giulia, Pasquale, Agosti, Erica, Pagliaro, Eleonora Semproni (Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Medicina Interna, 2, Emato- logia non tumorale, e Coagulopatie), Canetta, Ciro, Valter, Monzani, Valeria, Savojardo, Giuliana, Ceriani, Christian Folli (Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Medicina Interna Alta Intensità di Cure), Francesco, Salerno, Giada Pallini (IRCCS Policlinico San Donato, e Università di Milano, San Donato Milanese, Fabrizio, Montecucco, Luciano, Ottonello, Lara, Caserza, Giulia, Vischi, Salam, Kassem, Luca Liberale (IRCCS Ospedale Policlinico San Martino, e Università di Genova, Genova, Clinica Medica, 1, Medicina Interna, e Specialità Mediche), Nicola Lucio Liberato, Tiziana Tognin (ASST di Pavia, UOSD Medicina Interna, Ospedale di Casorate Primo, Pavia), Francesco, Purrello, Antonino Di Pino, Salvatore Piro (Ospedale Garibaldi Nesima, Catania, Giorgia, Renzo, Rozzini, Lina, Falanga, Maria Stella Pisciotta, Francesco Baffa Bellucci, Stefano Buf- felli, Camillo, Ferrandina, Francesca, Mazzeo, Elena, Spazzini, Giulia, Cono, Giulia Cesaroni (Ospedale Poliambulanza, Brescia, Medicina Interna, e Geriatria), Giuseppe, Montrucchio, Paolo, Peasso, Edoardo, Favale, Cesare, Poletto, Carl, Margaria, Maura Sanino (Dipartimento di Scienze Mediche, Università di Torino, Città della Scienza, e della Salute, Torino, Medicina Interna, 2 Unità Indirizzo d'Urgenza), Franc- esco Violi, Ludovica Perri (Policlinico Umberto, I, Prima Clinica Medica), Guasti, Luigina, Rotunno, Francesca, Castiglioni, Luana, Maresca, ANDREA MARIA, Squizzato, Alessandro, Campiotti, Leonardo, Ales- sandra Grossi, Diprizio, ROBERTO DAVIDE, Francesco Dentali (Università degli Studi dell'Insubria, Ospedale di Circolo, e Fondazione Macchi, Varese, Elena, Medicina, e Geriatria), Marco, Bertolotti, Chiara, Mussi, Giulia, Lancellotti, Maria Vittoria Libbra, Matteo, Galassi, Yasmine, Grassi, Alessio, Greco, Elena, Bigi, Elisa, Pellegrini, Laura, Orlandi, Giulia, Dondi, Lucia Carulli (Università di Modena, e Reggio Emilia, Azienda Ospedaliero-Universitaria di Modena, Ospedale Civile di Baggiovara, Unità Operativa di Geriatria), Angela, Sciacqua, Maria, Perticone, Rosa, Battaglia, Raffaele, Maio, Aleandra, Scozzafava, Valentino, Condoleo, Tania, Falbo, Lidia, Colangelo, Marco Filice, Elvira Clausi (Università Geriatriche), Vincenzo, Stanghellini, Eugenio, Ruggeri, Sara del Vec- chio, Ilaria Benzoni (Dipartimento di Scienze Mediche, e Chirurgiche, Unità Operativa di Medicina Interna, Orsola-Malpighi, Università degli Studi di Bologna/ Azienda Ospedaliero- Universitaria S., Bologna), Andrea, Salvi, Roberto, Leonardi, Giampaolo Damiani (Spedali Civili di Brescia, Medicina Generale), U. O. 3a., Gianluca, Moroncini, William, Capeci, Massimo, Mattioli, Giuseppe Pio Martino, Lorenzo, Biondi, Pietro, Pettinari, Monica, Ormas, Emanuele, Filippini, Devis, Benfaremo, Roberto Romiti (Clinica Medica, Azienda Ospedaliera Universitaria- Ospedali Riuniti di Ancona), Riccardo, Ghio, Anna Dal Col (Azienda Ospedaliera Università San Martino, Medicina, III), Salvatore, Minisola, Luciano, Colangelo, Mirella, Cilli, Giancarlo Labbadia (Poli- clinico Umberto, I, SMSC03Medicina Interna F, e Malattie Meta- boliche dell'osso), Antonella, Afeltra, Benedetta, Marigliano, Maria Elena Pipita (Policlinico Campus Biomedico Roma, Medicina, Clinica), Pietro, Castellino, Luca, Zanoli, Alfio, Gennaro, Agostino, Gaudio, Emanuele, Samuele Pignataro (Azienda Ospedaliera Universitaria Poli- clinico – V., Catania, Dipartimento di Medicina), Francesca, Mete, Miriam Gino (Ospedale degli Infermi di Rivoli, Medicina Interna)Guido Moreo, Gloria Pina (Clinica San Carlo Casa di Cura Polispecialistica, Paderno, Dugnano, Unità Operativa di Medicina Generale Emilio Bernardelli), Alberto Balle- strero, Fabio, Ferrando, Roberta, Gonella, Domenico, Cerminara, Paolo, Setti, Chiara, Traversa, Camilla Scarsi (Clinica Di Medicina Interna ad Indirizzo Oncologico, Azienda Ospedaliera Università San Martino di Genova), Bruno, Graziella, Stefano, Baldassarre, Salvatore, Fragapani, Gabriella Gruden (Medicina Interna III, Giovanni Battista Molinette, Ospedale S., Torino), Franco, Berti, Giuseppe, Famularo, Patrizia Tarsitani (Azienda Ospedaliera San Camillo Forlanini, Medicina Interna II), Roberto, Castello, Michela Pasino (Ospedale Civile Maggiore Borgo Trento, Medicina Generale, e Sezione di Decisione Cli- nica), Marcello Giuseppe Maggio Gian Paolo Ceda, Simonetta Mor- ganti, Andrea, Artoni, Margherita Grossi (Azienda Ospedaliero Uni- versitaria di Parma, Clinica Geriatrica), U. O. C., Stefano Del Giacco, Davide, Firinu, Giulia, Costanzo, Giacomo, Argiolas, Giovanni, Paoletti, Francesca Losa (Policlinico Universitario Duilio Casula, Azienda Ospedaliero-Universitaria di Cagliari, Cagliari, Allergologia ed Immunologia Clinica), Giuseppe, Montalto, Anna, Licata, Filippo Alessandro Montalto, Angelo Rizzo (Azienda Ospe- daliera Universitaria Policlinico Paolo Giaccone, UOC di Medicina Interna), Francesco, Corica, Giorgio, Basile, Antonino Cata- lano, Federica, Bellone, Martino, Concetto Principato (Azienda Ospedaliera Universitaria Policlinico G., Messina, Lorenzo, Malatino, Benedetta, Stancanelli, Valentina, Terranova, Salvatore Di Marca, Rosario Di Quattro, Lara La Malfa, Rossella Caruso (Azienda Ospedaliera per l'Emergenza Cannizzaro, Clinica Medica Università di Catania), Patrizia, Mecocci, Carmelinda, Ruggiero, della Misericordia, Virginia Boccardi (Università degli Studi di Perugia-Azienda Ospedaliera S. M., Struttura Complessa di Geriatria), Tiziana, Meschi, Andrea, Ticinesi, Antonio Nouvenne (Azienda Ospedaliera Universitaria di Parma, Medicina Interna e Lungodegenza Critica), U. O., Pietro, Minuz, Luigi, Fondrieschi, Giandomen- ico Nigro Imperiale, Sarah Morellini (Azienda Ospedaliera Universi- taria Verona, Policlinico GB Rossi, Medicina Generale per lo Studio ed il Trattamento dell’Ipertensione Arteriosa), Mario, Pirisi, Gian Paolo Fra, Daniele, Sola, Mattia Bellan (Azienda Ospedaliera Universitaria Maggiore della Carità, Medicina Interna 1), Roberto, Quadri, Erica, Larovere, Marco Novelli (Ospedale di Ciriè, Asl, To4, Emilio, Simeone, Rosa, Scurti, Fabio Tolloso (Ospedale Spirito Santo di Pescara, Geriatria), Roberto Tar- quini, Alice, Valoriani, Silvia, Dolenti, Giulia Vannini (Ospedale San Giuseppe, Empoli, USL Toscana Centro, Firenze, Medicina Interna I), Riccardo, Volpi, Pietro, Bocchi, Alessandro Vignali (Azienda Ospe- daliera Universitaria di Parma, Clinica, e Terapia Medica), Sergio, Harari, Chiara, Lonati, Federico, Napoli, Italia Aiello (Divisione di Medicina Interna, Multimedica, Ircss, Milano), Antonino Di Pino (Ospedale GaribaldiNesima, – Catania, Medicina Interna), U. O. C., Teresa, Salvatore, Lucio, Monaco, Vanvitelli, Carmen Ricozzi (Policlinico Università della Campania L., UOC Medicina Interna), Alberto, Pilotto, Ilaria, Indiano, Federica Gandolfo (Ente Ospe- daliero Ospedali Galliera Genova, SC Geriatria Dipartimento Cure Geriatriche, Ortogeriatria, e Riabilitazione)Franco Laghi Pasini, Pier Leopoldo Capecchi (Azienda Ospedaliera Universitaria Senese, Siena, Unità Operativa Complessa Medicina 2), Ranuccio, Nuti, Roberto Val- enti, Martina, Ruvio, Silvia, Cappelli, Alberto Palazzuoli (Azienda Ospedaliera Università Senese, Mauro Ber- nardi, Silvia Li Bassi, Luca, Santi, Giacomo Zaccherini (Azienda Ospe- daliera Policlinico Sant’Orsola-Malpighi, Semeiotica Medica Bernardi), Vittorio, Durante, Daniela, Tirotta, Giovanna Eusebi (Ospedale di Cattolica, Rimini, Marco, Cattaneo, Maria Valentina Amoruso, Paola, Fracasso, Cristina Fasolino (Azienda ospedaliera San Paolo, Moreno, Tresoldi, Enrica 13 Internal and Emergency Medicine Internal and Emergency Medicine Bozzolo, Sarah Damanti (IRCCS Ospedale San Raffaele, – Milano, Medicina Generale, e delle Cure Avanzate), Massimo, Porta, Miriam Gino (AOU Città della Salute e della Scienza di Torino, – Torino, and Medicina Interna, 1U).
- Subjects
Hospital cure ,Chronic obstructive pulmonary disease ,Heart failure ,Mortality ,Multimorbidity ,Prognosis - Published
- 2023
13. Global variation in anastomosis and end colostomy formation following left-sided colorectal resection
- Author
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Bhangu, A, Global variation in anastomosis and end colostomy formation following left-sided colorectal resection GlobalSurg Collaborative Appendix S1 Collaborators Authors (all the following are PubMed citable): Writing group: James, C Glasbey (UK), Adewale, O Adisa (Nigeria), Ainhoa Costas-Chavarri (Rwanda), Ahmad, U Qureshi (Pakistan), Jean, C Allen-Ingabire (Rwanda), Hosni Khairy Salem (Egypt), Anyomih Theophilus Teddy Kojo (Ghana), Stephen Tabiri (Ghana), Dmitri Nepogodiev (UK), Richard, J Lilford (UK), Ewen, M Harrison (UK), Thomas, D Pinkney (UK), Neil Smart (UK), Aneel Bhangu (UK, denotes joint first author Patient representatives: Azmina Verjee (UK), study guarantor)., Emmy Runigamugabo (Rwanda) Statistical analysis: James Glasbey, Aneel Bhangu Protocol development and project steering: Adesoji, O Ademuyiwa, Adewale, O Adisa, Maria Lorena Aguilera, Afnan, Altamini, Philip, Alexander, Sara, W Al-Saqqa, Giuliano, Borda-Luque, Jen, Cornick, Ainhoa, Costas-Chavarri, Thomas, M Drake, Stuart, J Fergusson, J Edward Fitzgerald, James, Glasbey, Allen Ingabire, J. C., Lawani, Ismaïl, Zahra, Jaffry, Hosni Khairy Salem, Chetan, Khatri, Andrew, Kirby, Anyomih Theophilus Teddy Kojo, Marie Carmela Lapitan, Richard, Lilford, Andre, L Mihaljevic, Midhun, Mohan, Dion, Morton, Alphonse Zeta Mutabazi, Dmitri, Nepogodiev, Faustin, Ntirenganya, Riinu, Ots, Francesco, Pata, Thomas, Pinkney, Tomas, Poškus, Ahmad Uzair Qureshi, Antonio Ramos-De la Medina, Sarah, Rayne, Gustavo, Recinos, Kjetil, Søreide, Catherine, A Shaw, Sebastian, Shu, Richard, Spence, Neil, Smart, Stephen, Tabiri, Ewen, M Harrison, Aneel Bhangu National leads (GlobalSurg-1) Lead coordinator, Australia, Neel Gobin, Brazil, Ana Vega Freitas, Canada, Nigel Hall, China, &, Hong Kong, Sung-Hee Kim, Egypt, Ahmed, Negida, Hosni, Khairy, England, Stephen, J Chapman, France, Alexis P Arnaud, Ghana, Stephen Tabiri, Guatemala, Gustavo Recinos, India, Cutting Edge Manipal, Indonesia, Radhian Amandito, Iraq, Marwan Shawki, Ireland, Michael Hanrahan, Italy, Francesco Pata, Lithuania, Justas Zilinskas, Malaysia, April Camilla Roslani, Cheng Chun Goh, Nigeria, Adesoji O Ademuyiwa, Northern Ireland, Gareth Irwin, Peru, Laura, Luque, Saudi, Arabia, Hunain, Shiwani, Afnan, Altamimi, Mohammed Ubaid Alsaggaf, Scotland, Stuart J Fergusson, South, Africa, Sri Lanka, Jenifa Jeyakumar, Sweden, Yucel Cengiz, Switzerland, Dmitri A Raptis, Wales, James, C Glasbey National leads (GlobalSurg-2) Argentina, Maria Marta Modolo, Australia, Dushyant, Iyer, Sebastian, King, Tom, Arthur, Bangladesh, Sayeda Nazmum Nahar, Barbados, Ade Waterman, Benin, Lawani Ismaïl, Botswana, Michael Walsh, Canada, Arnav, Agarwal, Augusto, Zani, Mohammed, Firdouse, Tyler, Rouse, China, Qinyang Liu, Colombia, Juan Camilo Correa, Egypt, Hosni Khairy Salem, Estonia, Peep Talving, Ethiopia, Mengistu Worku, France, Alexis Arnaud, Greece, Vassilis Kalles, Guatemala, Basant, Kumar, Sunil, Kumar, Ireland, Roy Quek, Italy, Luca, Ansaloni, Jordan, Ahmed Altibi, Lithuania, Donatas, Venskutonis, Justas, Zilinskas, Tomas, Poskus, Madagascar, John Whitaker, Malawi, Vanessa Msosa, Malaysia, Yong Yong Tew, Malta, Alexia, Farrugia, Elaine, Borg, Mexico, Antonio Ramos-De la Medina, Morocco, Zineb Bentounsi, Norway, Kjetil Søreide, Pakistan, Tanzeela Gala, Palestinian, Territory, Ibrahim, Al-Slaibi, Haya, Tahboub, Alser, Osaid H., Diego, Romani, Sebestian, Shu, Poland, Piotr Major, Romania, Aurel, Mironescu, Matei, Bratu, Amar, Kourdouli, Saint Kitts and Nevis, Aliyu Ndajiwo, Abdulaziz, Altwijri, Ahmad, Gudal, Al Faifi Jubran, Sierra Leone, Sam Seisay, Singapore, Bettina Lieske, Spain, Irene Ortega, Sri, Lanka, Jenifa, Jeyakumar, Senanayake, Kithsiri J., Sudan, Omar Abdulbagi, Switzerland, Dmitri Raptis, Turkey, Yuksel Altinel, United, Kingdom, Chia, Kong, Ella, Teasdale, Gareth, Irwin, Michael, Stoddart, Rakan, Kabariti, Sukrit, Suresh, United, States, Katherine, Gash, Ragavan, Narayanan, Zambia, Mayaba Maimbo Local collaborators (GlobalSurg-1) Argentina: Claudio Fermani, Ruben, Balmaceda, Australia: Ewan Macdermid, Maria Marta Modolo (Hospital Luis Lagomaggiore)., Neel, Gobin, Roxanne, Chenn, Cheryl Ou Yong, Michael Edye (Blacktown Hospital), Martin, Jarmin, Scott, K D'amours, Dushyant Iyer (Liverpool Hospital, The University Of New South Wales), Daniel, Youssef, Nicholas, Phillips, Jason Brown (Royal Brisbane &, Women'S, Hospital), Robert, George, Cherry, Koh, Oliver Warren (The Royal Prince Alfred Hospital, Australia), Isaac Hanley (The Tweed Hospital), Austria: Clemens Nawara, Marilla Dickfos (Toowoomba Hospital)., Dietmar, Öfner, Florian Primavesi (Department Of Surgery, Bangladesh: Ashrarur Rahman Mitul, Paracelsus Medical University Salzburg)., Khalid Mahmud (Dhaka Shishu (Children) Hospital), Margub, Hussain, Hafiz, Hakim, Tapan Kumar (Dhaka Medical College Hospital), Benin: Pamphile A Assouto, Antje Oosterkamp (Lamb Hospital)., Ismail, Lawani, Brunei: Aung Kyaw Tun, Yacoubou Imorou Souaibou (Centre National Hospitalier Et Universitaire Hubert Koutoukou Maga)., Chean Leung Chong (Pmmpmhamb Hospital) Giridhar, H Devadasar, Chean Leung Chong, Muhammad Rashid Minhas Qadir (Ssb Hospital), Kyaw Phyo Aung, Lee Shi Yeo, Brazil: Vanessa Dina Palomino Castillo, Chean Leung Chong (Ripas Hospital)., Monique Moron Munhoz, Gisele Moreira (Conjunto Hospitalar De Sorocaba), Luiz Carlos Barros De Castro Segundo, Salim Anderson Khouri Ferreira, Maíra Cassa Careta (Hospital Da Santa Casa De Misericórdia De Vitória), Stella Binna Kim, Alexandre Venancio De Sousa, Alyne Daltri Lazzarini Cury (Hospital De Caridade Sãƒo De Paula), Gustavo Peixoto Soares Miguel, Ana Vega Carreiro De Freitas, Barbara Pereira Silvestre (Hospital Estadual Doutor Jayme Dos Santos Neves), Julia Guasti Pinto Vianna, Carolina Oliveira Felipe, Luis Alberto Valente Laufer (Hospital Estadual Doutor Jayme Santos Neves), Fernanda, Altoe, Luana Ayres Da Silva, Marina Luiza Pimenta, Thiago Fernandes Giuriato, Paulo Alves Bezerra Morais, Jessica Souza Luiz (Hospital Estadual Dr Jayme Santos Neves), Rafael, Araujo, Juliana, Menegussi, Marisa, Leal, Caio Vinícius Barroso de Lima, Luiza Sarmento Tatagiba, Antônio Leal (Hospital Infantil Nosa Senhora Da Gloria), Diogo Vinicius dos Santos, Gustavo Pereira Fraga, Romeo Lages Simoes (Hospital De Clinicas, Cameroon: Samuel Nigo, University Of Campinas). Cambodia: Simon Stock (World Mate Emergency Hospital)., Juana, Kabba, Tagang Ebogo Ngwa, Canada: Sebastian King, James Brown (Mbingo Baptist Hospital)., Georges, Azzie, Sameer, Kushwaha, Arnav Agarwal (The Hospital For Sick Children), Karen, Bailey, Brian, Cameron, Michael Livingston (McMaster Children's Hospital), Alexandre, Horobjowsky, Dan, L Deckelbaum, Tarek Razek (Centre for Global Surgery, Chile: Boris Marinkovic, McGill University Health Centre)., Eugenio, Grasset, Nicole D'aguzan (Hospital Del Salvador), Julio, Jimenez, China: Zhongtao Zhang, Roberto Macchiavello (Hospital Luis Tisne)., Wei, Guo, Junyeong, Oh, Colombia: Irene Montes, Fei Zheng (Beijing Friendship Hospital)., Sebastian, Sierra, Manuela Mendez (Clinica Ces), Maria Isabel Villegas, Maria Clara Mendoza Arango, Ivan Mendoza (Clinica Las Vegas), Fred Alexander Naranjo Aristizã¡bal, Jaime Andres Montoya Botero, Victor Manuel Quintero Riaza (Hospital Pablo Tobon Uribe), Jakeline, Restrepo, Carlos, Morales, Maria Clara Mendoza Arango (Hospital Universitario San Vicente Fundacion), Herman, Cruz, Alejandro, Munera, Croatia: Robert Karlo, Maria Clara Mendoza Arango (Ips Universitaria Clinica Leon Xiii)., Edgar, Domini, Jakov Mihanovic (Zadar General Hospital), Mihael, Radic, Kresimir, Zamarin, Dominican Republic: Manuel Hache-Marliere, Nikica Pezelj (General Hospital Sibenik)., Sylvia Batista Lemaire, Ruben Rivas (Cedimat, - Centro De Diagnostico Medicina Avanzada, Egypt: Ahmed Khyrallh, Laboratorio Y Telemedicina)., Ahamed, Hassan, Gamal, Shimy, Mohamed, A Baky Fahmy (Al-Azher Universty Hospital), Ayman, Nabawi, Mohamed, Elfil, Mohamed, Ghoneem, Muhammad El-Saied Ahmad Muhammad Gohar, Mohamed, Asal, Mostafa, Abdelkader, Mahmoud, Gomah, Hayssam, Rashwan, Mohamed, Karkeet, Ahmed Gomaa (Alexandria Main University Hospital), Amr, Hasan, Ahmed, Elgebaly, Omar, Saleh, Ahmad Abdel Fattah, Abdullah, Gouda, Abd Elrahman Elshafay, Abdalla, Gharib, Ahmed, Menshawy, Mohammed, Hanafy, Abdullah, Al-Mallah, Mahmoud, Abdulgawad, Mohamad, Baheeg, Mohammed, Alhendy, Ibrahim, Abdelfattah, Abdalla, Kenibar, Omar, Osman, Mostafa, Gemeah, Ahmed, Mohammed, Abdalrahman, Adel, Abdelrahman, Mohammed, Abdelrahman, Sayed, Mohamed Abozaid (Al-Hussein Hospital), Ahmed Hafez El-Badri Kotb, Ali Amin Ahmed Ata, Mohammed, Nasr, Abdelrahman, Alkammash, Mohammed, Saeed, Nader Abd El Hamid, Attia Mohamed Attia, Ahmed Abd El Galeel, Eslam, Elbanby, Khalid Salah El-Dien, Usama, Hantour, Omar, Alahmady, Billal, Mansour, Amr Muhammad Elkorashy (Bab El-Shareia Hospital), Emad Mohamed Saeed Taha, Kholod Tarek Lasheen, Salma Said Elkolaly, Nehal Yosri Elsayed Abdel-Wahab, Mahmoud Ahmed Fathi Abozyed, Ahmed, Adel, Ahmed Moustafa Saeed, Gehad Samir El Sayed, Jehad Hassan Youssif (Banha University Hospital), Soliman Magdy Ahmed, Nermeen Soubhy El-Shahat, Abd El-Rahman Hegazy Khedr (Belbes Central Hospital), Abdelrhman Osama Elsebaaye, Mohamed, Elzayat, Mohamed, Abdelraheim, Ibrahim, Elzayat, Mahmoud, Warda, Khaled Naser El Deen, Abdelrhman Essam Elnemr, Omar, Salah, Mohamed, Abbas, Mona, Rashad, Ibrahim, Elzayyat, Dalia, Hemeda, Gehad, Tawfik, Mai, Salama, Hazem, Khaled, Mohamed Seisa (El Dawly Hospital, - Mansoura), Kareem, Elshaer, Abdelfatah, Hussein, Mahmoud Elkhadrawi (El Mahalla General Hospital), Ahmed Mohamed Afifi, Osama Saadeldeen Ebrahim, Mahmoud Mohamed Metwally (El, - Mataria Educational Hospital), Rowida, Elmelegy, Diaa Moustafa Elbendary Elsawahly, Hisham, Safa, Eman, Nofal, Mohamed, Elbermawy, Ahmed Abdelmotaleb Ghazy, Hisham, Samih, Asmaa, Abdelgelil, Sarah, Abdelghany, Ahmed El Kholy, Metwally, Aboraya, Fatma, Elkady, Mahmoud, Salma, Sarah, Samy, Reem, Fakher, Aya, Aboarab, Ahmed, Samir, Ahmed, Sakr, Abdelrahman, Haroun, Asmaa Abdel-Rahman Al-Aarag, Ahmed, Elkholy, Sally Elshanwany (El-Menshawy Hospital), Esraa Ghanem (Elshohadaa Central Hospital), Ahmed, Tammam, Ali Mohamed Hammad, Yousra El Shoura, Gehad El Ashal, Hosni Khairy (Kasr Alainy School Of Medicine), Sarah, Antar, Sara, Mehrez, Mahmoud, Abdelshafy, Maha Gamal Mohamad Hamad, Mona, Hosh, Emad, Abdallah, Basma, Magdy, Thuraya, Alzayat, Elsayed, Gamaly, Hossam, Elfeki, Amany, Abouzahra, Shereen, Elsheikh, Fatimah, I Elgendy (Mansoura University Hospitals), Fathia Abd El-Salam, Osama, Seifelnasr, Mohamed, Ammar, Athar, Eysa, Aliaa, Sadek, Aliaa Gamal Toeema, Aly, Nasr, Mohamed, Abuseif, Hagar, Zidan, Sara Abd Elmageed Barakat, Nadin, Elsayed, Yasmin Abd Elrasoul, Ahmed, Elkelany, Mohamed Sabry Ammar, Mennat-Allah, Mustafa, Yasmin, Hegazy, Mohamed, Etman, Samar, Saad, Mahmoud, Alrahawy, Ahmed, Raslan, Mahmoud, Morsi, Ahmed, Rslan, Ahmed, Sabry, Hager, Elwakil, Heba, Shaker, Yasmin, Abd-Elrasoul, Ahmed Elkelany (Menoufia University Hospitals), Hussein, El-Kashef, Mohamed, Shaalan, Areej Tarek (Minia University Hospital), Ayman, Elwan, Ahmed Ragab Nayel, Mostafa, Seif, Doaa, Emadeldin, Mohamed Ali Ghonaim, Ahmad, Almallah, Ahmed, Fouad, Eman Adel Sayma (New Damietta University Hospital), Ahmad, Elbatahgy, Angham Solaiman El-Ma'doul, Ahmed, Mosad, Hager, Tolba, Diaa Eldin Abdelazeem Amin Elsorogy, Hassan Ali Mostafa, Amira Atef Omar, Ola Sherief Abd El Hameed, Ahmed Lasheen (Quweisna Central Hospital In Quweisna), Yasser Abd El Salam, Ashraf, Morsi, Mohammed Ismail (Ras El Tin General Hospital), Hager Ahmed El-badawy, Mohamed, A Amer, Ahmed Sabry El-Hamouly, Attallah, Noura A., Omnia, Mosalum, Ahmed, Afandy, Ahmed, Mokhtar, Alaa, Abouelnasr, Sara, Ayad, Ramdan, Shaker, Rokia, Sakr, Ramadan, Shaker, Mahmoud, Amreia, Soaad, Elsobky, Mohamed, Mustafa, Ahmed Abo El Magd, Abeer, Marey, Amr Tarek Hafez, Mohamed, F Zalabia (Shebin Elkom Teaching Hospital, Menoufia), Mohamed Moamen Mohamed, Amr, Fadel, Emad Ali Ahmed (Sohag University Hospital), Ahmad, Ali, Mohammad Ghassan Alwafai, Abdullah, Dwydar, Sara, Kharsa, Ehab, Mamdouh, Hatem, El-Sheemy, Ibrahim, Alyoussef, Abouelatta Khairy Aly, Ahmad, Aldalaq, Ehab, Alnawam, Dalia Alkhabbaz (Souad Kafafi University Hospital), Mahmoud, Saad, Shady, Hussein, Ahmed Abo Elazayem, Ahmed, Meshref, Marwa, Elashmawy, Mohammed, Mousa, Ahmad, Nashaat, Sara, Ghanem, Zaynab, M Elsayed, Aya, Elwaey, Iman Elkadsh (Suez Canal University Hospitals), Mariam, Darweesh, Ahmed, Mohameden, Mennaallah Hafez (Suez General Hospital), Ahmed, Badr, Assmaa, Badwy, Mohamed Abd El Slam (Talla Central Hospital), Mohamed, Elazoul, Safwat, Al-Nahrawi, Lotfy, Eldamaty, Fathee, Nada, Mohamed, Ameen, Aya, Hagar, Mohamed, Elsehimy, Mohammad, Aboraya, Hossam, Dawoud, Shorouk El Mesery, Abeer El Gendy, Ahmed, Abdelkareem, Ahmed Safwan Marey, Mostafa, Allam, Sherif, Shehata, Khaled, Abozeid, Marwa, Elshobary, Ahmed, Fahiem, Sameh, Sarsik, Amel, Hashish, Mohamed, Zidan, Mohamed, Hashish, Shaimaa, Aql, Abdelaziz Osman Abdelaziz Elhendawy (Tanta University Hospital), Mohamed, Husseini, Esraa, Kasem, Ahmed, Gheith, Yasmin, Elfouly, Ahmed Ragab Soliman, Yasmein, Ibrahim, Nesma, Elfouly, Ahmed, Fawzy, Ahmed, Hassan, Mohammad, Rashid, Abdallah Salah Elsherbiny, Basem, Sieda, Nermin, M Badwi, Mohammed Mustafa Hassan Mohammed, Osama, Mohamed, Ethiopia: Mengistu Worku, Mohammad Abdulkhalek Habeeb (Zagazig University Hospitals)., Nichole Starr (Dessie Referral Hospital), Semay, Desta, Sahlu, Wondimu, Nebyou Seyoum Abebe (Minilik Ii Hospital), Efeson, Thomas, Frehun Ayele Asele, Daniel Dabessa (Myungsung Christian Medical Center), Nebiyou Seyoum Abebe, Finland: Panu Mentula, Abebe Bekele Zerihun (Tikur Anbessa Hospital)., Ari, Leppäniemi, France: Aurelien Scalabre, Ville Sallinen (Helsinki University Central Hospital)., Fernanda, Frade, Sabine Irtan (Trousseau Hospital Sorbonnes Universités, Upmc Univ Paris), Vivien, Graffeille, Elodie, Gaignard, Quentin Alimi (Chu De Rennes), Quentin, Alimi, Vivien, Graffieille, Elodie Gaignard (Fr Rennes University), Olivier, Abbo, Sofia, Mouttalib, Ourdia Bouali (Hopital Des Enfants), Erik, Hervieux, Yves, Aigrain, Nathalie Botto (Hopital Necker Enfants Malades), Alice, Faure, Lucile, Fievet, Nicoleta Panait (Hopitâl Nord), Emilie, Eyssartier, Francoise, Schmitt, Guillaume Podevin (Pediatric Surgery Department, University Hospital Of Angers, France), Valentine, Parent, Amandine, Martin, Alexis Pierre Arnaud (Rennes University Hospital), Cecile, Muller, Arnaud, Bonnard, Ghana: Francis Abantanga, Matthieu Peycelon (Robert Debré Children University Hospital)., Kwaku, Boakye-Yiadom, Mohammed Bukari (Komfo Anokye Teaching Hospital), Frank Owusu (Offinso District Hospital), Joseph, Awuku-Asabre, Lemuel Davies Bray (University For Development Studies, School Of Medicine And Health Sciences, General Surgery Department, Greece: Dimitrios Lytras, Tamale Teaching Hospital)., Kyriakos, Psarianos, Anastasia Bamicha (Achillopoyleio General Hospital Of Volos), Eirini Kefalidi (Attikon General Hospital), Georgios Gemenetzis (Attikon University Hospital), Christos, Dervenis, Nikolaos, Gouvas, Christos Agalianos (Konstantopouleio General Hospital Of Athens), Michail, Kontos, Gregory, Kouraklis, Dimitrios Karousos (Laiko University Hospital), Stylianos, Germanos, Constantinos Marinos (Larissa General Hospital), Christos, Anthoulakis, Nikolaos, Nikoloudis, Guatemala: Gustavo Recinos, Nikolaos Mitroudis (Serres General Hospital)., Sergio, Estupinian, Walter Forno (Hospital De Accidentes Ceibal), José René Arévalo Azmitia (Hospital General De Enfermedades, Cirugia De Emergencia, Instituto Guatemalteco De Seguridad Social), Carla Cecilia Ramãrez Cabrera (Hospital General De Enfermedades, Servicio De Cirugia Abdominal, Romeo, Guevara, Maria, Aguilera, Napoleon, Mendez, Cesar Augusto Azmitia Mendizabal, Pablo, Ramazzini, Mario Contreras Urquizu (Hospital General San Juan De Dios), Fernando, Tale, Rafael, Soley, Emanuel, Barrios, Emmanuel Barrios (Hospital Juan Jose Arevalo Bermejo), Daniel Estuardo Marroquín Rodríguez, Carlos Iván Pérez Velásquez, Sara María Contreras Mérida (Hospital Regional De Retalhuleu), Francisco, Regalado, Mario, Lopez, Miguel Siguantay (Hospital Roosevelt, Hong Kong: Fong Yee Lam, Guatemala)., Kylie Joan-yi Szeto, Charing Cheuk Ling Szeto, Wing Sum Li, Kieran Ka Kei Li, Man Fung Leung, Tony, Mak, India: SS Prasad, Simon Ng (Prince of Wales Hospital)., Anand, Kirishnan, Nidhi Gyanchandani (KMC Hospital), Bylapudi Seshu Kumar, Muthukumaran Rangarajan (Kovai Medical Centre &, Hospital), Sriram, Bhat, Anjana, Sreedharan, Kinnera (Kasturba Medical College), S. V., Yella, Reddy, Caranj, Venugopal, Sunil Kumar (Pes Institute Of Medical Sciences &, Research), Abhishek Mittal (Safdarjung Hospital, New, Delhi), Shravan, Nadkarni, Harish Neelamraju Lakshmi, Puneet Malik (Sawai Man Singh Medical College &, Hospitals, Jaipur, Rajasthan), Neel, Limaye, Srinivas, Pai, Pratik Jain (Sdm College Of Medical Sciences And Hospital), Monty, Khajanchi, Savni, Satoskar, Rajeev Satoskar (Seth Gordhandas Sunderdas Medical College And King Edward Memorial Hospital), Indonesia: Eldaa Prisca Refianti Sutanto, Abid Bin Mahamood (Travancore Medical College Hospital)., Daniel Ardian Soeselo, Chintya Tedjaatmadja (Atmajaya Hospital), Fitriana Nur Rahmawati, Radhian, Amandito, Maria Mayasari (Dr Cipto Mangunkusumo General Hospital, Iraq: Ruqaya Kadhim Mohammed Jawad Al-Hasani, Jakarta)., Hasan Ismael Ibraheem Al-Hameedi, Hasan Ismael Ibraheem, Israa Abdullah Aziz Al-Azraqi (Alsader Medical City), Lubna, Sabeeh, Rahma, Kamil, Marwan Shawki (Baghdad Medical City), Muwaffaq Mezeil Telfah (Department Of Surgery, College Of Medicine, University Of Mosul, Ireland: Amoudtha Rasendran, Al-Jumhoori Teaching Hospital)., Jacqueline, Sheehan, Robert, Kerley, Caoimhe, Normile, Richard William Gilbert, Jiheon, Song, Mohamed, Dablouk, Linnea, Mauro, Mohammed Osman Dablouk, Michael, Hanrahan, Paul, Kielty, Eleanor Marks (Cork University Hospital), Simon, Gosling, Michelle, Mccarthy, Amoudtha Rasendran (Cork University Hospital &, University College Cork), Diya, Mirghani, Syed Altaf Naqvi, Chee Siong Wong (Limerick University Hospital), Siyi, Chung, Reuban, D'Cruz, Ronan Cahill (Mater Misericordiae University Hospital), Simon George Gosling, Amoudtha, Rasendran, Ciara, Fahy, Diana Duarte Cadogan, Anna, Powell, Richard, Gilbert, Caroline, Clifford, Aoife Driscoll (Mercy University Hospital), Stassen, Paul, Chris, Lee, Ross Bowe (Midlands Regional Hospital Mullingar), William, Hutch, Michael Hanrahan (University College Cork), Helen, Mohan, Maeve, O'Neill, Italy: Piergiorgio Danelli, Kenneth Mealy (Wexford General Hospital)., Andrea, Bondurri, Anna Maffioli (Azienda Ospedaliera Luigi Sacco, - Polo Universitario), Mario, Pasini, Giacomo, Pata, Stefano Roncali (Azienda Ospedaliera Spedali Civili Di Brescia, - Chirurgia Generale), Paolo, Silvani, Michele, Carlucci, Roberto Faccincani (Irccs Ospedale San Raffaele), Luigi, Bonavina, Yuri, Macchitella, Chiara Ceriani (University of Milan, IRCCS Policlinico San Donato), Gregorio, Tugnoli, Salomone Di Saverio, Khaled Khattab (Maggiore Hospital), Miguel Angel Paludi, Domenica, Pata, Luigi Maria Cloro (Nicola Giannettasio Hospital), Andrea, Allegri, Federico Coccolini (Papa Giovanni Xxiii Hospital), Ezio, Veronese, Luca, Bortolasi, Alireza Hasheminia (San Bonifacio Hospital), Giacomo, Nastri, Massimiliano Dal Canto, Stefano Cucumazzo (Santa Croce Hospital), Angelo, Benevento, Gaetano Tessera (Sant'Antonio Abate Hospital, Gallarate), Pier Paolo Grandinetti, Alessio, Maniscalco, Giovanni Luca Lamanna (Santi Benvenuto, E Rocco Hospital Asur), Luca, Turati, Giovanni, Sgroi, Emanuele Rausa (Treviglio Hospital), Roberta, Villa, Michela, Monteleone, David Merlini (Unita' Di Chirurgia D'urgenza Azienda Ospedaliera Salvini), Federico, Coccolini, Andrea Allegri (Unit Of General Surgery, I, Papa Giovanni Xxiii Hospital), Veronica, Grassi, Roberto, Cirocchi, Libya: Hamza Waleed, Alban Cacurri (University Of Perugia)., Ahmed, Diab, Lithuania: Mantas Jokubauskas, Fathi Elzowawi (Misurata Central Hospital)., Karolis, Varkalys, Donatas Venskutonis (Kaunas Clinical Hospital), Robertas, Pranevicius, Viktorija Ambrozeviciute (Klaipedas Seaman Hospital), Simona, Juciute, Austė Skardžiukaitė (Lietuvos Sveikatos Mokslų Universitetas), Saulius, Bradulskis, Linas, Urbanavicius, Aiste, Austraite, Romualdas, Riauka, Zilvinas Dambrauskas (Lithuanian University Of Health Sciences), Paulius, Karumnas, Zigmantas, Urniezius, Reda Zilinskiene (Republic Hospital Of Kaunas), Anele Rudzenskaite (Republic Hospital Of Panevezys), Ausrine, Usaityte, Margarita, Montrimaite, Nerijus Kaselis (Republic Klaipeda Hospital), Andrius, Strazdas, Kristijonas Jokubonis (Stasys Kudirka Regional Hospital Of Alytus), Kornelija, Maceviciute, Virgilijus, Beisa, Kestutis, Strupas, Erikas Laugzemys (Vilnius University, Center Of Abdominal Surgery), Andrej, Kolosov, Valdemaras, Jotautas, Ignas Rakita (Vilnius University Hospital Santariskiu Clinics), Saulius, Mikalauskas, Darius, Kazanavicius, Rokas, Rackauskas, Virgilijus Beisa (Vilnius University Hospital Santariskiu Klinikos), Ritauras, Rakauskas, Malawi: Ross Coomber, Egle Preckailaite (Vsi Jonavos Ligonine)., Kenneth, Johnson, Malaysia: Dineshwary Periasammy, Jennifer Nowers (Queen Elizabeth Hospital)., Afizah, Salleh, Andre Das (Hospital Kajang), Reuben Goh Ern Tze, Milaksh Nirumal Kumar, Nik Azim Nik Abdullah (Sarawak General Hospital), Nik Ritza Kosai, Mustafa, Taher, Reynu Rajan (Universiti Kebangsaan Malaysia Medical Centre), Hoong Yin Chong, Malta: Marija Agius, Cheng Chun Goh (University Malaya Medical Centre)., Maureen, Bezzina, Roberta, Bugeja, Martinique, Vella-Baldacchino, Andrew, Spina, Josephine Psaila (Mater Dei Hospital, Martinique: Helene Francois-Coridon, Malta)., Cecilia, Tolg, Jean-Francois Colombani (Department Of Pediatric Surgery, Mother And Children's Hospital, Mexico: Carmina Diaz-Zorrilla, University Hospital Of Martinique)., Antonio Ramos-De La Medina, Mozambique: Mário Jacobe, Samantha Corro-Diaz Gonzalez (Hospital Español de Veracruz)., Domingos, Mapasse, New Zealand: Ramadan Oumer, Elizabeth Snyder (Hospital Central Maputo)., Mohammed Osman (Whangarei Hospital, Nigeria: Aminu Mohammad, Northland District Health Board)., Lofty-John, Anyanwu, Abdulrahman Sheshe (Aminu Kano Teaching Hospital), Alaba, Adesina, Olubukola, Faturoti, Ogechukwu Taiwo (Babcock University Teaching Hospital), Muhammad Habib Ibrahim, Abdulrasheed, A Nasir, Siyaka Itopa Suleiman (Federal Medical Centre, Birnin, Kebbi), Adewale, Adeniyi, Opeoluwa, Adesanya, Ademola Adebanjo (Federal Medical Centre), Roland, Osuoji, Kazeem, Atobatele, Ayokunle, Ogunyemi, Omolara, Williams, Mobolaji, Oludara, Olabode Oshodi (Lagos State University Teaching Hospital), Adesoji, Ademuyiwa, AbdulRazzaq Oluwagbemiga Lawal, Felix, Alakaloko, Olumide, Elebute, Adedapo, Osinowo, Christopher Bode(Lagos University Teaching Hospital), Abidemi Adesuyi (National Hospital Abuja), Adesoji, Tade, Adeleke, Adekoya, Collins Nwokoro (Olabisi Onabanjo University Teaching Hospital), Omobolaji, O Ayandipo, Taiwo Akeem Lawal, Akinlabi, E Ajao (University College Hospital), Samuel Sani Ali, Babatunde, Odeyemi, Samson Olori (University of Abuja Teaching Hospital), Ademola, Popoola, Ademola, Adeyeye, Lossius (Department Of Gastrointestinal Surgery, James Adeniran (University of Ilorin Teaching Hospital). Norway: William J., Olavs Hospital, St., Trondheim University Hospital), Ingemar Havemann (Soerlandet Hospital Kristiansand), Kenneth, Thorsen, Jon Kristian Narvestad, Kjetil Soreide (Stavanger University Hospital), Trude Beate Wold, Linn Nymo (University Hospital Of North Norway, Oman: Mohammed Elsiddig, Troms)., Pakistan: Kamran Faisal Bhopal, Manzoor Dar (Sohar Hospital)., Zainab, Iftikhar, Muhammad Mohsin Furqan (Bahawal Victoria Hospital), Bakhtiar, Nighat, Masood, Jawaid, Abdul Khalique (Dow University Hospital), Ahsan, Zil-E-Ali, Anam Rashid (Fatima Memorial Hospital), Hasnain Abbas Dharamshi, Tahira, Naqvi, Ahmad Faraz (Karachi Medical And Dental College, Abbasi Shaheed Hospital), Abdul Wahid Anwar, Tahir Muhammad Yaseen, Ghina Shamim Shamsi, Ghina, Shamsi, Tahir, Yaseen, Paraguay: Horacio Paredes Decoud, Wahid Anwer (The Indus Hospital)., Omar, Aguilera, Ismael Isaac Zelada Alvarez, Juan Marcelo Delgado, Gustavo Miguel Machain Vega, Peru: Wendy Leslie Messa Aguilar, Helmut Alfredo Segovia Lohse (Hospital De Clínicas)., Jose Antonio Cabala Chiong, Essalud), Ana Cecilia Manchego Bautista (Carlos Alberto Seguin Escobedo National Hospital., Eduardo, Huaman, Sergio, Zegarra, Rony Camacho (Hospital Necional Guillermo Almenara), Jose María Vergara Celis, Diego Alonso Romani Pozo (Hospital De Emergencias Pediatricas), José, Hamasaki, Edilberto, Temoche, Jaime Herrera-Matta (Hospital De Policia), Carla Pierina García Torres, Luis Miguel Alvarez Barreda, Ronald Renato Barrionuevo Ojeda (Hospital Goyeneche), Octavio Garaycochea (Hospital Ii -1 Minsa Moyobamba), Melanie Castro Mollo, Mitchelle Solange De Fã Tima Linares Delgado, Francisco Fujii (Hospital Maria Auxiliadora), Ana Cecilia Manchego Bautista, Wendy Leslie Messa Aguilar, Jose Antonio Cabala Chiong (Hospital Nacional Carlos Alberto Seguin), Susana Yrma Aranzabal Durand, Carlos Alejandro Arroyo Basto, Nelson Manuel Urbina Rojas (Hospital Nacional Edgardo Rebagliati Martins-Essalud), Sebastian Bernardo Shu Yip, Ana Lucia Contreras Vergara, Andrea Echevarria Rosas Moran, Giuliano Borda Luque, Manuel Rodriguez Castro, Ramon Alvarado Jaramillo (Hospital Nacional Cayetano Heredia), George Manrique Sila, Crislee Elizabeth Lopez, Mardelangel Zapata Ponze De Leon, Massiell, Machaca, Ronald Coasaca Huaraya, Andy, Arenas, Crislee, López, Clara Milagros Herrera Puma, Wilfredo, Pino, Christian, Hinojosa, Melanie Zapata Ponze De Leon, Susan, Limache, George Manrrique Sila, Portugal: Renato Melo, Layza-Alejandra Mercado Rodriguez (Hospital Regional Honorio Delgado Espinoza)., Jose, Costa-Maia, Romania: Ionasc Dan, Nuno Muralha (Servico De Cirurgia Geral - Centro Hospitalar Sao Joao - Porto). Reunion: Frederique Sauvat (Chu Reunion)., Mircea, Hogea, Pandi Eduard (Emergency Clinical Hospital Brasov), Razvan-Matei, Bratu, Mircea, Beuran, Ionut-Bogdan, Diaconescu, Bogdan-Valeriu, Martian, Florin-Mihail, Iordache, Mihaela Vartic (Emergency Clinical Hospital Bucharest), Lucian Corneliu Vida, Liviu Iuliu Muntean, Rwanda: Vizir Jean Paul Nsengimana (Chuk), Aurel Sandu Mironescu (Spitalul Clinic De Copii Brasov)., Alice, Niragire, Jean De La Croix Allen Ingabire, San Marino: Nicola Zanini, Eugene Niyirera (University Teaching Hospital Of Kigali)., Elio, Jovine, Alomar, Giovanni Landolfo (San Marino State Hospital). Saudi Arabia: Ibrahim N., Alnuqaydan, Saleh A., Altwigry (Buraydah Central Hospital), Abdulrahman M., Moayad, Othman, Nohad Osman (Imam Abdulrahman Al Faisal Hospital), Enas Alqahtani (King Abdulaziz Hospital Al Ahsa National Guard), Mohammed, Alzahrani, Rifan, Alyami, Emad Aljohani (King Abdulaziz Medical City), Ibrahim, Alhabli, Zaher, Mikwar, Sultan Almuallem (King Abdulaziz Medical City (King Khalid National Guard Hospital, Jeddah), Emad, Aljohani, Mohammed Alzahrani (King Abdulaziz Medical City, Riyadh), Abrar, Nawawi, Mohamad, Bakhaidar, Maghrabi, Ashraf A., Mohammed, Alsaggaf, Murad, Aljiffry, Abdulmalik, Altaf, Ahmad, Khoja, Alaa, Habeebullah, Nouf Akeel (Department of Surgery, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi, Arabia), Nashat, Ghandora, Abdullah, Almoflihi, Abdulmalik Huwait (King Fahad General Hospital), Abeer, Al-shammari, Mashael Al-Mousa (King Fahad Hospital), Masood, Alghamdi, Walid, Adham, Bandar, Albeladi, Muayad Ahmed Alfarsi, Atif, Mahdi, Saad Al Awwad (King Fahd Hospital), Thamer, Nouh, Mazen Hassanain (King Khaled University Hospital, King Saud University), Salman, Aldhafeeri, Nawal, Sadig, Osama Algohary (King Khalid General Hospital), Mohannad, Aledrisy, Ahmad Alrifaie (King Khalid National Guard Hospital), Mohammed, Alrowais, Amani Althwainy (Department of Surgery, Alaa, Shabkah, Uthman, Alamoudi, Mawaddah Alrajraji (National Guard Hospital), Basim, Alghamdi, Saud, Aljohani, Abdullah Daqeeq (Rcymc), South Africa: Vicky Jennings, Jubran J Al-Faifi (Security Forces Hospital)., Nyawira, Ngayu, Rachel Moore (Chris Hani Baragwanath Academic Hospital), Victor Kong (Edendale Hospital), Hayden, Kretzmann, Katie, Connor, Daniel Nel (Frere Hospital), Colleen, Sampson, Eugenio Panieri (Groote Schuur), Nosisa Sishuba (Helen Joseph Hospital, Department Of Surgery, University Of The Witwatersrand), Myint, Tun, Albert Mohale Mphatsoe, Jo-Anne Carreira (Leratong Hospital), Mark Wagener (Ngwelezana Hospital), Stefan, Botes, Spain: Fernando Fernandez-Bueno (Hospital Central De La Defensa Gomez Ulla), Danelo Du Plessis (Rob Ferreira Hospital)., Jose, Aguilar-Jimenez, Sms), Jose Andres Garcia-Marin (Hospital Morales Meseguer., Lorena Solar García, Luis Joaquín García Florez, Rubén Darío Arias Pacheco (Hospital San Agustín), Janet, Pagnozzi, Jimy Harold Jara Quezada, Jose Luis Rodicio, German, Minguez, Raquel, Rodríguez-Uría, Paul, Ugalde, Camilo, Lopez-Arevalo, Luis, Barneo, Jessica Patricia Gonzales Stuva (Hospital Universitario Central De Asturias), Irene, Ortega-Vazquez, Lorena, Rodriguez, Sri Lanka: Prasad Pitigala Arachchi, Norberto Herrera (Severo Ochoa University Hospital)., Wanigasekara Senanayake Mudiyanselage Kithsiri Janakantha Senanayake, Lalith Asanka Jayasooriya Jayasooriya Arachchige (Department Of General Surgery, Teaching Hospital Kandy), Sivasuriya, Sivaganesh, Dulan Irusha Samaraweera, Sudan: Ahmed Elgaili Khalid Musa, Vimalakanthan Thanusan (National Hospital Of Sri Lanka)., Reem Mohammed Hassan Balila, Mohamed Awad Elkarim Hamad Mohamed (Ibrahim Malik Teaching Hospital), Hussein, Ali, Hagir Zain Elabdin, Alaa Hassan (Jarash International Specialized Hospital), Sefeldin, Mahdi, Hala, Ahmed, Sahar Abdoun Ishag Idris (Khartoum Teaching Hospital), Makki, Elsayed, Mohammed, Elsayed, Sweden: Magnus Boijsen, Mohamed Mahmoud (Omdurman Teaching Hospital)., Per-Olof Lundgren (Capio St Goran Hospital), Ulf, Gustafsson, Ali Kiasat (Danderyds Hospital), Fredrik, Wogensen, Emma, Jurdell, Anders Thorell (Department Of Surgery, Ersta, Hospital, Stockholm), Hildur, Thorarinsdottir, Maria Utter (Helsingborgs Lasarett), Sami Martin Sundstrom (Hudiksvall Sjukhus), Cecilia, Wredberg, Ann Kjellin (Karolinska Universitetssjukhuset), Johanna, Nyberg, Bjorn Frisk (Skaraborg Hospital Skovde), Malin, Sund, Linda, Andersson, Ulf Gunnarsson (Department Of Surgical And Perioperative Sciences, Umea University and Umea University Hospital), Yücel, Cengiz, Sandra, Ahlqvist, Ida Björklund (Sundsvall Hostpital) Hanna Royson, Per Weber (Vaexjoe Central Hospital), Hans-Ivar, Pahlsson, Eva Borin (Visby Hospital, Department Of Surgery), Maria Hjertberg (Vrinnevi Hospital), Hanna, Royson, Switzerland: Roger Schmid, Per Weber (Vaxjo Central Hospital)., Debora, Schivo, Vasileios Despotidis (Bürgerspital Solothurn), Stefan, Breitenstein, Ralph, F Staerkle, Erik Schadde (Kantonsspital Winterthur), Fabian, Deichsel, Alexandra, Gerosa, Antonio Nocito (Kantonsspital Baden), Dimitri Aristotle Raptis, Barbara, Mijuskovic, Markus, Zuber, Lukas Eisner (Kantonsspital Olten), Swantje, Kruspi, Katharina Beate Reinisch, Christin Schoewe (Kreisspital Fuer Das Freiamt Muri Ag), Allan, Novak, Palma, Adrian F., Gerfried Teufelberger (Kreisspital Muri, Tanzania: Msafiri Kimaro, Department Of Surgery)., Rachel King (Mbalizi Christian Designated Hospital) Turkey: Ali Zeynel Abidin Balkan, Mehmet, Gumar, Mehmet Ali Yavuz (Harran University Research And Treatment Hospital), Ufuk, Karabacak, Gokhan, Lap, Bahar Busra Ozkan (Ondokuz Mayis University, Medical, Faculty), Bahar Busra Ozkan, United Kingdom: Ryan Adams, Murat Karakahya (Ordu University Training And Research Hospital)., Robert, Morton, Liam, Henderson, Ruth, Gratton, Keiran David Clement, Kate Yu-Ching Chang, David, Mcnish, Ryan, Mcintosh, William Milligan (Aberdeen Royal Infirmary), Brendan, Skelly, Hannah, Anderson-Knight, Roger Lawther (Altnagelvin Area Hospital), Jemina, Onimowo, Veereanna, Shatkar, Shivanee Tharmalingam (Barking, Havering And Redbridge University Hospitals Trust (Queens Hospital, Romford), Evelina, Woin, Tessa, Fautz, Oliver Ziff (Barnet General Hospital), Shiva, Dindyal, Sam, Arman, Shagorika, Talukder, Vijay, Gadhvi, Shagorika Talukder (Basildon And Thurrock University Foundation Trust), Luen Shaun Chew, Jonathan Heath (Blackpool Victoria Teaching Hospitals), Natalie, Blencowe, Sally, Hallam, Katherine Gash (Bristol Royal Infirmary), Gurdeep Singh Mannu, Dimitris-Christos, Zachariades, Ailsa Claire Snaith (Buckinghamshire NHS Trust), Thusitha Sampath Hettiarachchi, Arjun, Nesaratnam, James Wheeler (Cambridge University Hospitals NHS Foundation Trust), Darragh, Mccullagh, Joshua Michael Clements, Ata Khan (Causeway Hospital), Foteini, Koumpa, Christina, Neophytou, Jessica, Roth, Wai Cheong Soon, Mohammed, Deputy, Ahmed, Ahmed, Annelisse, Ashton, Joe, Vincent, Jack, Almy, Taufiq, Khan, John Lee, Y Allen, Charlotte Jane Mcintyre, Dominic Charles Marshall (Charing Cross Hospital, Imperial College Healthcare NHS Trust), Mark, Sykes, Nebil, Behar, Harriet Jordan (Chelsea And Westminster Hospital), Yaseen, Rajjoub, Thomas Sherman (Cheltenham General Hospital), Timothy, White, Anna, Watts, Rohan Ardley (Chesterfield Royal Hospital NHS Foundation Trust), Tan, Arulampalam, Apar, Shah, Damien Brown (Colchester Hospital University NHS Foundation Trust), Emma, Blower, Paul, Sutton, Konstantinos, Gasteratos, Dale Vimalachandran (Countess Of Chester Hospital), Cathy, Magee, Andrew Mcguigan (Craigavon Area Hospital), Stephen, Mcaleer, Clare Morgan (Daisy Hill Hospital), Sarah Braungart (Department Of Paediatric Surgery, Leeds General Infirmary), Kirsten, Lafferty, Peter, Labib, Andrei, Tanase, Clodagh, Mangan, Lillian, Reza, Clodagh Mangan (Derriford Hospital), Helen, Woodward, Craig, Gouldthorpe, Megan Turner (Diana Princess Of Wales Hospital), Jonathan R, L Wild, Tom AM Malik, Victoria, K Proctor (Doncaster Royal Infirmary NHS Foundation Trust), Kalon, Hewage, James Davies (Dorset County Hospital), Andre, Dubois, Sayed, Sarwary, Ali, Zardab, Alan, Grant, Robert Mcintyre (Dr Grays Hospital), Yogendra Praveen Mogan, Weiguang, Ho, Bryon Frankie Hon Khi Chong (Dumfries And Galloway Royal Infirmary), Shirish, Tewari, Gemma, Humm, Eriberto Farinella (East And North Hertfordshire NHS Trust Lister Hospital) Nigel, J Hall, Naomi, J Wright, Christina, P Major (Evelina Children's Hospital), Thelma, Xerri, Phoebe De Bono, Jasim, Amin, Mustafa, Farhad, Camilleri-Brennan, John F., Andrew G, N Robertson, Joanna, Swann, James, Richards, Aijaz, Jabbar, Myranda, Attard, Hannah, Burns, Euan, Macdonald, Matthew, Baldacchino, Jennifer, Skehan, Julian Camilleri-Brennan (Forth Valley Royal Hospital), Tom Falconer Hall, Madelaine, Gimzewska, Greta Mclachlan (Frimley Park Hospital), Jamie, Shah, James Giles (George Elliot Hospital), Selina, Chiu, Beatrix, Weber, Selina Man Yeng Chiu, Saskia Highcock (Gilbert Bain Hospital), Maleeha, Hassan, William, Beasley, Apostolos, Vlachogiorgos, Stephen, Dias, Geta, Maharaj, Rosie Mcdonald (Glangwili General Hospital), Alisdair, Macdonald, Paul, Witherspoon, Alan Baird (Glasgow Southern General Hospital), Panchali, Sarmah, Nikki, Green, Haney Youssef (Good Hope Hospital), Kate, Cross, Clare, M Rees, Bernard Van Duren (Great Ormond Street Hospital For Children NHS Foundation Trust), Emma Upchurch (Great Western Hospital), Khurram, Khan, Haytham, Abudeeb, Ahmed Hammad (Hairmyres Hospital, Nhs, Lanarkshire), Sharad, Karandikar, Doug, Bowley, Ahmed Karim (Heart Of England Foundation Trust), Witold, Chachulski, Liam, Richardson, Giles, Dawnay, Ben, Thompson, Ajayesh, Mistry, Aneel, Bhangu, Millika, Ghetia, Sudipta, Roy, Ossama, Al-Obaedi, Kaustuv Das (Hereford County Hospital), Ash, Prabhudesai, Cocker, Dm, Jessica Juliana Tan (Hillingdon Hospital), Robert, Tyler, Filippo Di Franco, Shruti Ayyar (Hinchingbrooke Hospital), Sayinthen, Vivekanantham, Shyam Gokani (Imperial College London), Michael, Gillespie, Katrin Gudlaugsdottir (Inverclyde Royal Hospital), Theodore, Pezas, Chelise, Currow, Matthew Young-Han Kim (Ipswich Hospital NHS Trust), Amerdip, Birring, Joanne, Edwards, Ased, Ali, Suparna, Das, Madan, Jha, Kieran Atkinson (James Cook University Hospital), Joshua, Luck, Thomas, Fozard, Michael Puttick (John Radcliffe Hospital), Yahya, Salama, Rohi, Shah, Ahmad Aboelkassem Ibrahem, Hamdi, Ebdewi, Gianpiero, Gravante, Saleem El-Rabaa (Kettering General Hospital), Henry, Nnajiuba, Rebecca, Allott, Aman Bhargava (King George Hospital), Zoe, Chan, Zaffar Hassan (Kings College Hospital), Misty, Makinde, David, Hemingway, Ramzana, Dean, Alexander, Boddy, Ahmed, Aber, Vijay Patel (Leicester Royal Infirmary), Jehangirshaw Parakh (Leighton Hospital, - Mid Cheshire NHS Foundation Trust), Sunil Parthiban (Lister Hospital), Harmony Kaur Ubhi, Simon-Peter Hosein (Luton And Dunstable Hospital), Simon, Ward, Kamran Malik (Macclesfield District General Hospital), Leifa, Jennings, Tom, Newton, Mirna, Alkhouri, Min Kyu Kang, Christopher, Houlden, Jonathan Barry (Morriston Hospital), Imtanan, Raza, Alistair, Farquharson, Sanjeet Bhattacharya (NHS Ayrshire), William, Milligan, Kate, Chang, Liam Henderson (NHS Grampian), Michael S, J Wilson, Yan Ning Neo, Ibrahim, Ibrahim, Emily, Chan, Fraser, S Peck, Pei, J Lim, Alexander, S North, Rebecca, Blundell, Adam Williamson (Ninewells Hospital, NHS), Dina, Fouad, Ashish Minocha (Norfolk And Norwich University Hospital), Kathryn, Mccarthy, Emma, Court, Alice Chambers (North Bristol NHS Trust), Jenna, Yee, Ji Chung Tham, Ceri Beaton (North Devon District Hospital), Una, Walsh, Joseph, Lockey, Salman, Bokhari, Lara, Howells, Megan, Griffiths, Laura Yallop (Northwick Park Hospital), Shailinder, Singh, Omar, Nasher, Paul Jackson (Nottingham Children's Hospital At Queens Medical Centre Campus), Michael, Puttick, Thomas Fozard (Oxford University Hospitals), Abdul Muiz Shariffuddin, Weng Chee Ho, Michael Sj Wilson, Gurpreet Pabla (Perth Royal Infirmary), Saed, Ramzi, Shady, Zeidan, Jennifer Doughty (Plymouth Hospitals NHS Trust), Sidhartha, Sinha, Ross, Davenport, Jason Lewis (Princess Alexandra Hospital), Leo, Duffy, Elizabeth, Mcaleer, Eleanor Williams (Princess Of Wales Hospital), Robin, Som, Omar Javed (Queen Elizabeth Hospital Woolwich), Matthew, Boal, Nicola, Harrison, Habib, Tafazal, Omar, Javed, Tom, Brogden, Ewen Griffiths (Queen Elizabeth Hospital Birmingham) Rhalumi Daniel Obute, Thomas, E Glover, David, J Clark (Queen Elizabeth Hospital King's Lynn), Mohamed, Boshnaq, Mansoor, Akhtar, Pascale, Capleton, Samer, Doughan, Mohamed, Rabie, Ismail Mohamed (Queen Elizabeth The Queen Mother Hospital), Duncan, Samuel, Lauren, Dickson, Matthew, Kennedy, Eleanor, Dempster, Emma, Brown, Natalie, Maple, Eimear, Monaghan, Bernhard, Wolf, Alicia Garland (Raigmore Hospital), Arthur, Mcphee, David, Anderson, Robert Anderson (Royal Alexandria Hospital), Sarah, Hassan, Dave Smith (Royal Bolton Hospital), Jonathan, Lund, Catherine, Boereboom, Jennifer, Murphy, Gillian, Tierney, Samson Tou (Royal Derby Hospital), Eleanor Franziska Zimmermann, Neil James Smart, Andrea Marie Warwick (Royal Devon And Exeter National Health Service Foundation Trust), Theodora, Stasinou, Ian, Daniels, Kim Findlay-Cooper (Royal Devon &, Exeter NHS Foundation Trust), Stefan, Mitrasinovic, Swayamjyoti, Ray, Massimo, Varcada, Rovan, D'Souza, Sharif Omara (Royal Free Hospital), Matthew, Spurr, Lucienne, Parkinson, Anthony Hanks (Royal Glamorgan Hospital), Jennifer, Ma, Emily, Abington, Meera, Ramcharn, Gethin Williams (Royal Gwent Hospital), Joseph, Winstanley, Kennedy, Ewan D., Emily NW Yeung (Royal Hospital For Sick Children), Catrin, Jones, Stephen, O'Neill, Shujing Jane Lim, Ignatius, Liew, Hari, Nair, Cameron, Fairfield, Julia, Oh, Samantha, Koh, Andrew, Wilson, Catherine Fairfield (Royal Infirmary Of Edinburgh), Delran, Anandkumar, Ashok, Kirupagaran, Timothy, F Jones, Hew Dt Torrance, Alexander, J Fowler, Charmilie, Chandrakumar, Priyank, Patel, Syed Faaz Ashraf, Lakhani, Sonam M., Aaron Lawson Mclean, Sonia Basson (Royal London Hospital), Jeremy, Batt, Catriona, Bowman, Natasha Benons (Royal United Hospital Bath), Clare, Mason, Rebecca, Harrison, John Quayle (Salford Royal NHS Foundation Trust), Tom, Barker, Virginia, Summerour, Edward Harper (Sandwell And West Birmingham Hospitals NHS Trust), Caroline, Smith, Matthew Hampton (Sheffield Children's Hospital), Sophie, K Pitt, Alex, E Ward, Timothy, O’Connor, Emily, G Heywood, Thomas, M Drake (Sheffield Teaching Hospitals NHS Foundation Trust), Abeed, Chowdhury, Sina, Hossaini, Nicholas Fs Watson (Sherwood Forest Hospitals NHS Foundation Trust), Doug, Mckechnie, Ayaan, Farah, Anita Chun (Southend University Hospital), Hoey, Koh, Grace, Lim, Graham Sunderland (Southern General Hospital), Laura, Gould, Alice Chambers (Southmead Hospital), C Munipalle, P, Rooney, H, D R, L Browning (Southmead Hospital, North Bristol NHS Trust), Bernadette, Pereira, Kristof Nemeth (St Georges Healthcare NHS Trust), Emily, Decker, Stefano, Giuliani, George's Healthcare NHS Trust And University), Aly Shalaby (St., Shafaque, Shaikh, Chern Yan Tan, James's University Hospital), Ebrahim Y A Palkhi (St., Aleksandra, Szczap, Swathikan, Chidambaram, Chee Yang Chen, Kavian, Kulasabanathan, Srishti Chhabra (St Mary's Hospital), Elisabeth, Kostov, Philippe, Harbord, Mary's Hospital), James Barnacle (St., Madan Mohan Palliyil, Mina, Zikry, Johnathan, Porter, Charef, Raslan, Shazia, Hafiz, Niksa, Soltani, Katie Baillie (Stockport NHS Foundation Trust), Priyanka, Singh, Shailee, Sheth, Kishen, Patel, Mahry, Khalili, Jeesoo, Choi, Matthew Benger (St Thomas' Hospital), Lucy, Marples, Alastair, Macfarlane, Thomas Hospital), Ramesh Thurairaja (St., Tamsin, Boyce, Harriet, Whewell, Elin Jones (The Royal Gwent Hospital), Francesca, Th'Ng, Nichola Robertson (The Royal Infirmary Of Edinburgh), Ahmad, Mirza, Haroon, Saeed, Simon Galloway (The University Hospital Of South Manchester), Gia, Elena, Mohammad, Afzal, Mohamed Zakir (United Lincolnshire Hospitals, - Pilgrim Hospital), Peter, Sodde, Charles, Hand, Aiesha, Sriram, Tamsyn, Clark, Patrick, Holton, Amy Livesey (University Hospital Coventry And Warwickshire), Yashashwi, Sinha, Fahad Mujtaba Iqbal, Indervir Singh Bharj (University Hospital Of North Midlands), Adriana, Rotundo, Cara, Jenvey, Robert Slade (University Hospital Of North Staffordshire NHS Trust), David, Golding, Samuel, Haines, Ali Adel Ne'ma Abdullah, Thomas, W Tilston, Dafydd, Loughran, Danielle, Donoghue, Lorenzo, Giacci, Mohamed Ashur Sherif, Peter, Harrison, Alethea Tang (University Hospital Of Wales), Deevia Kotecha (University Hospitals Leicester, - Leicester Royal Infirmary), Mohamed, Elshaer, Tomas, Urbonas, Amjid, Riaz, Annie, Chapman, Parisha, Acharya, Joseph Shalhoub (Watford General Hospital), Cathleen, Grossart, David McMorran (Western General Hospital), Makhosini, Mlotshwa, William, Hawkins, Sofronis Loizides (Western Sussex Hospitals NHS Trust), Kandaswamy, Krishna, Melanie, Orchard, Chik Wai Ho (Weston General Hospital), Peter, Thomson, Shahab, Khan, Fiona, Taylor, Jalak, Shukla, Emma Elizabeth Howie (Whipps Cross University Hospital), Linda, Macdonald, Olusegun, Komolafe, Neil Mcintyre (Wishaw General Hospital), James, Cragg, Jody, Parker, Duncan Stewart (Wrexham Maelor Hospital), Luke, Lintin, Julia, Tracy, United States: George Molina, Tahir Farooq (Yeovil District Hospital)., Haytham, Kaafarani, Laura Luque (Massachusetts General Hospital), Robel, Beyene, Jack, Sava, Mark Scott (Medstar Washington Hospital Center), Mamta, Swaroop, Raelene Kennedy (Northwestern Memorial Hospital), Ijeoma, A Azodo, Daithi, Heffernan, Tristen, Chun, Andrew Stephen (The Rhode Island Hospital), Melanie, Sion, Weinstein, Michael S., Viren Punja (Thomas Jefferson University Hospital), Nikolay, Bugaev, Monica, Goodstein, Shadi Razmdjou (Tufts Medical Center), Eric, Etchill, Juan Carlos Puyana, Matthew Kesinger (University of Pittsburgh Medical Center, - Presbyterian Hospital), Lena, Napolitano, Kathleen, To, Zambia: Oliver Todd, Mark Hemmila (University Of Michigan)., Edward, Jenner, Local collaborators (GlobalSurg-2) Albania: Besmir Grizhja, Ellen Hoogakker (St Francis Hospital)., Shpetim, Ymeri, Gezim Galiqi (Spitali Rajonal Shkoder), Argentina: Roberto Klappenbach, Diego, Antezana, Alvaro Enrique Mendoza Beleño, Cecilia, Costa, Belen, Sanchez, Susan Aviles (Hospital Zonal General De Agudos Simplemente Evita), Claudio Gabriel Fermani, Rubén, Balmaceda, Santiago, Villalobos, Lagomaggiore, Juan Manuel Carmona (Hospital Luis C., Mendoza), Australia: Daniel Hamill, Peter, Deutschmann, Simone, Sandler, Daniel Cox (Alice Springs Hospital), Ram, Nataraja, Claire, Sharpin, Damir Ljuhar (Monash Medical Center), Demi Gray, Morgan Haines (Port Macquarie Base Hospital), Dush, Iyer, Nithya, Niranjan, Scott D'Amours (Liverpool Hospital), Morvarid, Ashtari, Bangladesh: Ashrarur Rahman Mitul, Helena Franco (Gold Coast University Hospital)., Sabbir Karim (Dhaka Shishu (Children) Hospital), Nowrin F. Aman, Mahnuma Mahfuz Estee (Holy Family Red Crescent Medical College &, Umme, Salma, Joyeta, Razzaque, Tasnia Hamid Kanta (Dhaka Medical College And Hospital), Sayeeda Aktar Tori, Shadid, Alamin, Swapnil, Roy, Shadid Al Amin, Rezaul Karim (Armed Forces Medical College), Muhtarima, Haque, Amreen, Faruq, Farhana Iftekhar (Birdem Bangladesh Institute Of Research And Rehabilitation In Diabetes Endocrine And Metabolic Disorder General Hospital), Barbados: Margaret O'Shea, Greg, Padmore, Belarus: Andrey Litvin, Ramesh Jonnalagadda (Queen Elizabeth Hospital)., Aliaksandr, Filatau, Dzmitry, Paulouski, Maryna, Shubianok, Tatsiana Shachykava (Gomel Regional Clinical Hospital), Dzianis, Khokha, Vladimir Khokha (City Hospital) Benin: Fernande Djivoh, Francis Dossou (Centre National Hospitalier Et Universitaire Hubert Koutoukou Maga), Djifid Morel Seto, Dansou Gaspard Gbessi, Bruno, Noukpozounkou, Yacoubou Imorou Souaibou (Centre National Hospitalier Et Universitaire Hubert Koutoukou Maga), Kpèmahouton René Keke, Fred Hodonou (Clinique Vignon), Ernest Yemalin Stephane Ahounou, Thierry Alihonou (Hopital El Fateh), Max, Dénakpo, Burundi: Carlos Nsengiyumva, Germain Ahlonsou (Hospital Saint Luc). Botswana: Alemayehu Ginbo Bedada (Princess Marina Hospital)., Sandrine, Kwizera, Cambodia: Philip Choi, Venerand Barendegere (Hopital Militaire De Kamenge)., Simon Stock (World Mate Emergency Hospital) Canada: Luai Jamal, China: Tzu-Ling Chen, Arnav Agarwal (The Hospital For Sick Children)., Colombia: Irene Montes, Chingwan Yip (Fudan University Affiliated Huashan Hospital)., Felipe, Zapata, Sebastian Sierra (Clinica CES), Maria Isabel Villegas Lanau, Ivan Mendoza Restrepo (Clinica Las Vegas), Ruben Santiago Restrepo Giraldo, Croatia: Edgar Domini, Maria Clara Mendoza Arango (Hospital Universitario San Vicente Fundación)., Robert, Karlo, Egypt: Mohamed Youssef, Jakov Mihanovic (Zadar General Hospital)., Waleed, Thabet, Aly, Sanad, Ahmed, Zaki, Noran, Abdel-Hameed, Mohamed, Mostafa, Muhammad Fathi Waleed Omar, Ahmed, Ghanem, Adel, Denewar, Eman, Emara, Eman, Rashad, Ahmad, Sakr, Rehab, Elashry, Sameh Emile (Mansoura University Hospital), Toqa, Khafagy, Sara, Elhamouly, Arwa, Elfarargy, Amna Mamdouh Mohamed, Ghada Saied Nagy, Abeer, Esam, Eman, Elwy, Aya, Hammad, Salwa, Khallaf, Eman, Ibrahim, Ahmed, Saidbadr, Ahmed, Moustafa, Amany Eldosouky Mohammed, Mohammed, Elgheriany, Eman, Abdelmageed, Eman Abd Al Raouf, Esraa Samir Elbanby, Maha, Elmasry, Mahitab Morsy Farahat, Eman Yahya Mansor, Eman Magdy Hegazy, Esraa, Gamal, Heba, Gamal, Hend, Kandil, Doaa Maher Abdelrouf, Mohamed Moaty (Menofiya University Hospital), Dina, Gamal, Nada, El-Sagheer, Mohamed, Salah, Salma, Magdy, Asmaa, Salah, Ahmed, Essam, Ahmed, Ali, Mahmoud, Badawy, Sara Ahmed (Beni Suef University Hospital), Mazed, Mohamed, Abdelrahman, Assal, Mohamed, Sleem, Mai, Ebidy, Aly Abd Elrazek, Diaaaldin, Zahran, Nourhan, Adam, Mohamed, Nazir, Adel, B Hassanein, Ahmed, Ismail, Amira, Elsawy, Rana, Mamdouh, Mohamed, Mabrouk, Lopna Ahmed Mohamed Ahmed, Mohamed Hassab Alnaby, Eman, Magdy, Manar, Abd-Elmawla, Marwan, Fahim, Bassant, Mowafy, Moustafa Ibrahim Mahmoud, Meran, Allam, Muhammad, Alkelani, Noran Halim El Gendy, Mariam Saad Aboul-Naga, Reham Alaa El-Din, Alyaa Halim Elgendy, Mohamed, Ismail, Mahmoud, Shalaby, Aya Adel Elsharkawy, Mahmoud Elsayed Moghazy, Khaled Hesham Elbisomy, Hend Adel Gawad Shakshouk, Mohamed Fouad Hamed, Mai Mohamed Ebidy, Mohamed Karkeet (Alexandria Main UniversIty Hospital), Hayam, Ahmed, Israa, Adel, Mohammad Elsayed Omar, Mohamed, Ibrahim, Omar, Ghoneim, Omar, Hesham, Shimaa, Gamal, Karim, Hilal, Omar, Arafa, Sawsan Adel Awad, Menatalla, Salem, Fawzia Abdellatif Elsherif, Nourhan, Elsabbagh, Aboelsoud, Moustafa R., Ahmed Hossam Eldin Fouad Rida, Amr, Hossameldin, Ethar, Hany, Yomna Hosny Asar, Nourhan, Anwar, Mohamed, Gadelkarim, Samar, Abdelhady, Eman Mohamed Morshedy, Reham, Saad, Nourhan, Soliman, Mahmoud Salama (Alexandria Medical Research Institute), Eslam, Ezzat, Arwa, Mohamed, Arwa, Ibrahim, Alaa, Fergany, Sara, Mohammed, Aya, Reda, Yomna, Allam, Hanan Adel Saad, Afnan, Abdelfatah, Aya Mohamed Fathy, Ahmed, El-Sehily, Esraa Abdalmageed Kasem, Ahmed Tarek Abdelbaset Hassan, Ahmed Rabeih Mohammed, Abdalla Gamal Saad, Arij, Ibrahim, Amr, Hassaan, Mohammed Mustafa Mohammed, Ghada, Elhoseny, Mohamed, Magdy, Esraa Abd Elkhalek, Yehia, Zakaria, Tarek, Ezzat, Ali Abo El Dahab, Mohamed, Kelany, Sara, Arafa, Osama Mokhtar Mohamed Hassan, Nermin Mohamed Badwi, Ahmad Saber Sleem, Hussien, Ahmed, Kholoud, Abdelbadeai, Mohamed Abozed Abdullah (Faculty Of Medicine, Zagazig, University), Muhammad Amsyar Auni Lokman, Suraya, Bahar, Anan Rady Abdelazeam, Abdelrahman, Adelshone, Muhammad Bin Hasnan, Athirah, Zulkifli, Siti Nur Alia Kamarulzamil, Abdelaziz, Elhendawy, Aliang, Latif, Ahmad Bin Adnan, Shahadatul, Shaharuddin, Aminah Hanum Haji Abdul Majid, Dina, Al-Marakby, Mohamad Jeffrey Bin Ismail, Elissa Rifhan Mohd Basir, Citra Dewi Mohd Ali, Aya Yehia Ata (Faculty Of Medicine, Tanta, University), Maha, Nasr, Asmaa, Rezq, Ahmed, Sheta, Sherif, Tariq, Abd Elkhalek Sallam, Abdelrhman KZ Darwish, Sohaila, Elmihy, Shady, Elhadry, Ahmed, Farag, Haidar, Hajeh, Abdelaziz, Abdelaal, Amro, Aglan, Ahmed, Zohair, Mahitab, Essam, Omar, Moussa, Esraa, El-Gizawy, Mostafa, Samy, Safia, Ali, Esraa, Elhalawany, Ahmed, Ata, Mohamed El Halawany, Mohamed, Nashat, Samar, Soliman, Alaa, Elazab, Mostada Samy (El-Menshawy General Hospital), Mohamed, A Abdelaziz, Khaled, Ibrahim, Ahmed mohamed Ibrahim, Ammar, Gado, Usama Hantour (Al-Hussein Hospital), Esraa Alm Eldeen, Mohamed Reda loaloa, Arwa, Abouzaid, Mostafa Ahmed Bahaa Eldin, Eman, Hashad, Fathy, Sroor, Doaa, Gamil, Eman Mahmoud Abdulhakeem, Mahmoud, Zakaria, Fawzy, Mohamed, Marwan, Abubakr, Elsayed, Ali, Hesham, Magdy, Menna Tallah Ramadan, Mohamed Abdelaty Mohamed, Salma, Mansour, Hager Abdul Aziz Amin, Ahmed Rabie Mohamed, Mahmoud, Saami, Nada Ahmed Reda Elsayed, Adham, Tarek, Sabry Mohy Eldeen Mahmoud, Islam Magdy El Sayed, Amira, Reda, Martina Yusuf Shawky, Mohammed Mousa Salem, Shahinaz Alaa El-Din, Noha Abdullah Soliman, Muhammed, Talaat, Shahinaz, Alaael-Dein, Ahmed Abd Elmoen Elhusseiny, Noha, Abdullah, Mohammed, Elshaar, Aya AbdelFatah Ibraheem, Hager, Abdulaziz, Mohammed Kamal Ismail, Mona Hamdy Madkor, Mohamed, Abdelaty, Sara Mahmoud Abdel-Kader, Osama Mohamed Salah (Benha Faculty Of Medicine), Mahmoud, Eldafrawy, Ahmed Zaki Eldeeb, Mostafa Mahmoud Eid (October, 6 University Hospital), Attia, Attia, Ayman Shwky (Bab El-Shareia University Hospital), Mohamed Adel Badenjki, Abdelrahman, Soliman, Samaa Mahmoud Al Attar (The Memorial Soaad Kafafi University Hospital), Farrag, Sayed, Fahd Abdel Sabour, Azizeldine, Mohammed G., Muhammad, Shawqi, Abdullah, Hashim, Ahmed, Aamer, Ahmed Mahmoud Abdelraouf, Mahmoud, Abdelshakour, Amal, Ibrahim, Basma, Mahmoud, Mohamed Ali Mahmoud, Mostafa, Qenawy, Rashed, Ahmed M., Ahmed, Dahy, Marwa, Sayed, Shamsedine, Ahmed W., Bakeer, Mohamed, Ahmad, Hasan, Saad, Mahmoud M., Khalil Abdul Bassit (Assiut University Hospital), Nadia Khalid Abd El-Latif, Nada, Elzahed, Ahmed El Kashash, Nada Mohamed Bekhet, Sarah, Hafez, Ahmed, Gad, Mahmoud Elkhadragy Maher, Ahmed Abd Elsameea, Mohamed, Hafez, Ahmad, Sabe, Ataa, Ahmed, Ahmed, Shahine, Khaled, Dawood, Shireen, Gaafar, Reem, Husseiny, Omnia, Aboelmagd, Ahmed, Soliman, Nourhan, Mesbah, Hossam, Emadeldin, Amgad Al Meligy, Amira Hassan Bekhet, Doaa, Hasan, Khaled, Alhady, Ahmad Khaled Sabe, Elnajjar, Mahmoud A., Majed, Aboelella, Ward, Hamsho, Ihab, Hassan, Hala, Saad, Galaleldin, Abdelazim, Hend, Mahmoud, Noha, Wael, Ahmedali, M Kandil, Ahmed, Magdy, Shimaa Said Elkholy, Badr Eldin Adel, Kareem, Dabbour, Saged, Elsherbiney, Omar, Mattar, Abdulshafi Khaled Abdrabou, Mohammed Yahia Mohamed Aly, Abdelrahman, Geuoshy, Ahmedglal, Elnagar, Saraibrahim, Ahmed, Ibrahem, Abdelmotaleb, Amr Ahmed Saleh, Manar, Saeed, Shady, Mahmoud, Badreldin Adel Tawfik, Samar Adel Ismail, Esraay, Zakaria, Gad, Mariam O., Mohamed Salah Elhelbawy, Monica, Bassem, Noha, Maraie, Nourhan Medhat Elhadary, Nourhan, Semeda, Shaza Rabie Mohamed, Hesham Mohammed Bakry, AA Essam (Kasr Al-Ainy Faculty Of Medicine, Cairo, University), Dina, Tarek, Khlood, Ashour, Alaa, Elhadad, Abdulrahman, Abdel-Aty, Ibrahim, Rakha, Sara Mamdouh Matter, Rasha, Abdelhamed, Omar, Abdelkader, Ayat, Hassaan, Yasmin, Soliman, Amna, Mohamed, Sara Amr Mohamed Farouk, Eman Mohamed Ibrahim, Esraa El-Taher (Faculty Of Medicine Seuz Canal University), Merna, Mostafa, Mohamed Fawzy Mahrous Badr, Rofida, Elsemelawy, Aya, El-Sawy, Ahmad, Bakr, Ahmad Abdel Razaq Al Rafati (Smouha University Hospital), Estonia: Sten Saar, Arvo, Reinsoo, Peep Talving (The North Estonia Medical Centre), Ethiopia: Nebyou Seyoum, Tewodros, Worku, Agazi Fitsum (Addis Ababa University, College Of Health Sciences, School Of Medicine), Finland: Matti Tolonen, Ville Sallinen (Helsinki University Hospital), France: Benoît Parmentier, Matthieu, Peycelon, Sabine Irtan (Trousseau Hospital, APHP), Sabrina Dardenne, Elsa Robert (GHICL), Betty, Maillot, Etienne, Courboin, Alexis Pierre Arnaud, Juliette Hascoet (CHU Rennes), Amir Ait Kaci, Thomas Prudhomme (CHU Toulouse), Quentin, Ballouhey, Céline, Grosos, Laurent Fourcade (CHU Limoges), Tolg, Cecilia, Colombani, Jean-Francois, Francois-Coridon Helene (CHU Martinique), Xavier Delforge, Elodie Haraux (CHU Amiens Picardie), Bertrand, Dousset, Roberto, Schiavone, Sebastien Gaujoux (Cochin, - APHP), Jean-Baptiste, Marret, Aurore, Haffreingue, Julien Rod (CHU Caen), Mariette Renaux-Petel (CHU Rouen), Jean-François, Lecompte, Jean, Bréaud, Pauline Gastaldi (CHU Lenval Nice), Chouikh, Taieb, Raquillet, Claire, Echaieb Anis (Hopital Robert Ballanger, Paris), Nasir, Bustangi, Manuel, Lopez, Aurelien Scalabre (CHU De Saint Etienne), Maria Giovanna Grella (CHU Poitiers), Aurora, Mariani, Guillaume, Podevin, Françoise Schmitt (CHU Angers), Aline, Broch, Cecile Muller (Hopital Necker Enfants Malades, Ghana: Stephen Tabiri, APHP)., Dickson, Bandoh, Francis, Abantanga, Martin, Kyereh, Hamza, Asumah, Eric Kofi Appiah, Paul Wondoh (Tamale Teaching Hospital), Adam, Gyedu, Charles, Dally, Kwabena, Agbedinu, Michael, Amoah, Abiboye Yifieyeh (Kwame Nkrumah University of Science and Technology/Komfo Anokye Teaching Hospital), Particks Hospital), Frank Owusu (St., Mabel, Amoako-Boateng, Makafui, Dayie, Richmond, Hagan, Sam Debrah (Cape Coast Teaching Hosital), Micheal, Ohene-Yeboah, Joe-Nat, Clegg-Lampety, Victor, Etwire, Jonathan, Dakubo, Samuel, Essoun, William, Bonney, Hope, Glover-Addy, Samuel, Osei-Nketiah, Joachim, Amoako, Niiarmah, Adu-Aryee, William, Appeadu-Mensah, Antoinette, Bediako-Bowan, Florence Dedey (Korle Bu Teaching Hospital), Mattew, Ekow, Emmanuel, Akatibo, Musah Yakubu (Baptist Medical Center, Nalerigu), Hope Edem Kofi Kordorwu, Kwasi, Asare-Bediako, Enoch Tackie (Keta Hospital District Hospital, Keta), Kenneth, Aaniana, Emmanuel, Acquah, Richard, Opoku-Agyeman, Anthony, Avoka, Kwasi, Kusi, Kwame Maison (Techiman Holy Family Hospital), Frank Enoch Gyamfi (Berekum Holy Family Hospital), Gandau Naa Barnabas, Saiba Abdul-Latif (Upper West Regional Hospital), Philip Taah Amoako (Samapa Government Hospital), Anthony Davor, Victor Dassah (Upper East Regional Hospital), Mary's Hospital), Enoch Dagoe (St., Prince Kwakyeafriyie (Essumejaman Sda Hospital, Dominase), Elliot, Akoto, Eric, Ackom, Ekow Mensah (Dormaa Presbyterian Hospital), Ebenezer Takyi Atkins, Christian Lari Coompson (Brongho-Ahafo Regional Hospital, Sunyani) Greece: Nikolaos Ivros, Christoforos, Ferousis, Vasileios, Kalles, Christos, Agalianos, Ioannis, Kyriazanos, Christos, Barkolias, Angelos, Tselos, Georgios, Tzikos, Evangelos Voulgaris (Naval And Veterans Hospital), Dimitrios, Lytras, Athanasia, Bamicha, Kyriakos Psarianos (Achillopoyleio General Hospital Of Volos), Anastasios Stefanopoulos (General Hospital Of Nafplio, Department Of Surgery), Ioannis, Patoulias, Dimitrios, Sfougaris, Gennimatas Hospital), Ioannis Valioulis (G., Dimitrios, Balalis, Dimitrios, Korkolis, Dimitrios, K Manatakis (Saint Savvas Cancer Hospital), Georgios, Kyrou, Georgios, Karabelias, Iason-Antonios Papaskarlatos (General And Oncological Hospital Of Kifissia-Athens), Kolonia, Konstantina, Nikolaos, Zampitis, Stylianos Germanos (General Hospital Of Larissa), Aspasia, Papailia, Theodosios, Theodosopoulos, Georgios Gkiokas (2nd Dept Of Surgery, Aretaieion, Hospital, National, &, Kapodistrian University Of Athens School Of Medicine), Magdalini, Mitroudi, Christina, Panteli, Thomas, Feidantsis, Gennimatas General Hospital), Konstantinos Farmakis (G., Dimitrios, Kyziridis, Orestis, Ioannidis, Styliani Parpoudi (4th Surgical Department, Aristotle University Of Thessaloniki, General, Hospital, Papanikolaou), Georgios Gemenetzis, Stavros Parasyris (Attikon University Hospital), Michail Margaritis (Serres General Hospital), Guatemala: Maria-Lorena Aguilera-Arevalo, Otto, Coyoy-Gaitan, Javier Rosales (Hospital General San Juan De Dios), Luis, Tale, Emmanuel Barrios (Juan Josè Arevalo Bermejo), Servio Tulio Torres Rodriguez, Carlos Paz Galvez, Danilo Herrera Cruz (Hospital San Vicente), Guillermo Sanchez Rosenberg, Alejandro, Matheu, David Monterroso Cohen (Hospital Herrera Llerandi), Haiti: Marie Paul, Angeline Charles (Hopital Universitaire De Mirebalais), Hong Kong SAR, China: Justin Chak Yiu Lam, Man Hon Andrew Yeung, Chi Ying Jacquelyn Fok, Ka Hin Gabriel Li, Anthony Chuk-Him Lai, Yuk Hong Eric Cheung, Hong Yee Wong, Ka Wai Leung, Tien Seng Bryan Lee, Wai Him Lam, Weihei, Dao, Stephanie Hiu-wai Kwok, Tsz-Yan Katie Chan, Yung Kok Ng, TWC Mak (Prince Of Wales Hospital), Qinyang, Liu, Chi Chung Foo, James Yang (University Of Hong Kong), India: Basant Kumar, Ankur, Bhatnagar, Vijaid Upadhyaya (Sanjay Gandhi Post Graduate Institute Of Medical Sciences), Sunil Kumar (Excelcare Hospital), Uday, Muddebihal, Wasim, Dar, KC Janardha (Manipal Hospital), Philip Alexander, Neerav Aruldas (Lady Willingdon Hospital), Indonesia: Fidelis Jacklyn Adella, Anthonius Santoso Rulie, Ferdy, Iskandar, Jonny Setiawan (Atma Jaya Hospital), Cicilia Viany Evajelista, Hani, Natalie, Oen Surakarta Hospital), Arlindawati Suyadi (Dr., Rudy, Gunawan, Herlin, Karismaningtyas, Lusi Padma Sulistianingsih Mata, Ferry Fitriya Ayu Andika, Afifatun, Hasanah, T Ariani Widiastini, Nurlaila Ayu Purwaningsih, Annisa Dewi Fitriana Mukin, Dina Faizatur Rahmah, Hazmi Dwinanda Nurqistan, Hasbi Maulana Arsyad, Novia Adhitama (Rsd Dr Soebandi), Wifanto Saditya Jeo, Nathania, Sutandi, Audrey, Clarissa, Phebe Anggita Gultom, Matthew, Billy, Andreass, Haloho, Nadya, Johanna, Felix Lee (Rsupn Cipto Mangunkusumo), Ireland: Radin Mohd Nurrahman Radin Dorani, Martha, Glynn, Mohammad, Alherz, Wennweoi, Goh, Shiwani, Haaris A., Lorraine, Sproule, Conlon (Tallaght Hospital, Kevin C., Trinity College Dublin) Israel: Miklosh Bala, Asaf Kedar (Hadassah Hebrew University Medical Center), Italy: Luca Turati, Federica, Bianco, Francesca Steccanella (Treviglio Hospital), Gaetano, Gallo, Mario, Trompetto, Giuseppe Clerico (Department of Colorectal Surgery, Rita Clinic, S., Vercelli), Matteo, Papandrea, Giuseppe, Sammarco, Rosario Sacco (Department of Medical and Surgical Sciences, Policlinico Universitario Mater Domini Campus Salvatore Venuta, Catanzaro), Luisa Giavarini (Sant'Antonio Abate Hospital, Mariano Cesare Giglio, Luigi, Bucci, Gianluca, Pagano, Viviana, Sollazzo, Roberto, Peltrini, Gaetano Luglio (Federico II University Of Naples), Arianna, Birindelli, Gregorio Tugnoli (Maggiore Hospital), Pietro, Mingrone, Domenica Pata (Nicola Giannettasio Hospital, Rossano), Francesco, Selvaggi, Lucio, Selvaggi, Gianluca, Pellino, Natale Di Martino (Universitá della Campania 'Luigi Vanvitelli', Naples), Gianluca, Curletti, Paolo, Aonzo, Raffaele Galleano (Ospedale Santa Corona, Pietra Ligure (SV)), Stefano, Berti, Elisa, Francone, Andrea Hospital, Silvia Boni (S., Poll-Asl, 5, Spezia), La, Lorenzon, Laura, Annalisa lo Conte, Genoveffa Balducci (Sant’Andrea Hospital, Sapienza University of Rome), Gianmaria Confalonieri, Giovanni Pesenti (Azienda Ospedaliera Alessandro Manzoni), Laura, Gavagna, Giorgio, Vasquez, Simone, Targa, Savino, Occhionorelli, Dario Andreotti (Azienda Ospedaliero-Universitaria Di Ferrara), Andrea, Armellini, Spedali Civili Di Brescia), Deborah Chiesa (A. O., Fabrizio, Aquilino, Nicola, Chetta, Arcangelo Picciariello (Azienda Ospedaliero Universitaria Consorziale Policlinico Di Bari), Mohamed, Abdelkhalek, Andrea, Belli, Silvia De Franciscis (Istituto Nazionale Tumori Fondazione, Pascale-, I. R. C. C. S. )., Annamaria, Bigaran, Alessandro, Favero, 5 Friuli Occidentale), Stefano M. M Basso (Azienda Per L'assistenza Sanitaria N., Paola, Salusso, Martina, Perino, Sylvie, Mochet, Diego, Sasia, Francesco, Riente, Marco Migliore (Azienda Sanitaria Ospedaliera San Luigi Gonzaga), David, Merlini, Silvia, Basilicò, Carlo Corbellini (Ospedale Di Rho, - ASST Rhodense), Veronica, Lazzari, Luigi Bonavina (IRCCS Policlinico, University of Milano, San, Donato), Daniele, Angelieri, Diego, Coletta, Federica, Falaschi, Marco, Catani, Claudia, Reali, Mariastella, Malavenda, Celeste Del Basso, Sergio, Ribaldi, Massimo, Coletti, Andrea, Natili, Norma, Depalma, Immacolata, Iannone, Angelo, Antoniozzi, Davide Rossi (Policlinico Umberto, I Emergency Surgery Department), Daniele, Gui, Gerardo, Perrotta, Matteo, Ripa, Francesco Ruben Giardino, Maurizio Foco (Fondazione Policlinico Universitario Agostino Gemelli), Erika, Vicario, Gabriela Elisa Nita (AO Papa Giovanni XXIII), Nicoletta, Leone, Anna Maffioli (Ospedale Sacco), Andrea, Simioni, Davide De Boni, Sandro Pasquali (IOV, - Istituto Oncologico Veneto), Elena, Goldin, Elena, Vendramin, Eleonora Ciccioli (Azienda Ospedaliera di Padova), Umberto, Tedeschi, Paola, Violi, Tommaso, Campagnaro, Simone, Conci, Giovanni, Lazzari, Calogero, Iacono, Alfredo, Gulielmi, Serena Manfreda (Azienda Ospedaliera Universitaria Integrata di Verona), Anna, Rinaldi, Maria Novella Ringressi, Beatrice Brunoni (Azienda Ospedaliera Universitaria Careggi), Giuseppe, Salamone, Mirko, Mangiapane, Paolino De Marco, Antonella La Brocca, Roberta, Tutino, Vania, Silvestri, Leo, Licari, Tommaso, Fontana, Nicolò, Falco, Gianfranco Cocorullo (Policlinico Paolo Giaccone di Palermo), Mostafa, Shalaby, Pierpaolo, Sileri, Claudio Arcudi (Policlinico Tor Vergata Hospital, Rome) Jordan: Isam Bsisu, Khaled, Aljboor, Lana, Abusalem, Aseel, Alnusairat, Ahmad, Qaissieh, Emad, Al-Dakka, Ali, Ababneh, Oday Halhouli (Jordan University Hospital), Kenya: Taha Yusufali, Hussein Mohammed (Kenyatta National Hospital), Justus, Lando, Robert, Parker, Wairimu Ndegwa (Tenwek Hospital), Lithuania: Mantas Jokubauskas, Jolanta, Gribauskaite, Donatas Venskutonis (Lithuanian University Of Health Sciences), Justas, Kuliavas, Audrius, Dulskas, Samalavicius (Klaipeda University Hospital, Narimantas E., National Cancer Institute), Kristijonas, Jasaitis, Audrius, Parseliunas, Viktorija, Nevieraite, Evelina, Slapelyte, Edvinas, Dainius, Zilvinas, Dambrauskas, Andrejus, Subocius, Linas, Venclauskas, Antanas, Gulbinas, Simona, Kasputyte, Deimante, Mikuckyte, Mindaugas, Kiudelis, Tomas, Jankus, Steponas Petrikenas (Lithuanian University of Health Sciences), Matas, Pažuskis, Zigmantas, Urniežius, Mantas Vilčinskas (Republican Hospital of Kaunas), Vincas Jonas Banaitis, Vytautas, Gaižauskas, Edvard, Grisin, Povilas, Mazrimas, Mantas, Drungilas, Karolis, Lagunavicius, Vytautas, Lipnickas, Dovilè, Majauskyté, Tomas, Abaliksta, Laimonas, Uščinas, Gintaras, Simutis, Adomas, Ladukas, Donatas, Danys, Erikas, Laugzemys, Elena Zdanyte Sruogiene (Vilnius University Hospital), Petras, Višinskas, Reda, Žilinskienė, Deividas Dragatas (Hospital Of Jonava), Andrius Burmistrovas, Zygimantas Tverskis (Taurage Hospital), Arturas, Vaicius, Ruta, Mazelyte, Antanas Zadoroznas (Viesoji Istaiga Rokiskio Rajono Ligonine), Nerijus Kaselis, Greta Žiubrytė (Republican Hospital Of Klaipeda), Madagascar: Finaritra Casimir Fleur Prudence Rahantasoa, Luc Hervé Samison, Fanjandrainy, Rasoaherinomenjanahary, Todisoa Emmanuella Christina Tolotra (Joseph Ravoahangy Andrianavalona Hospital), Malawi: Cornelius Mukuzunga, Vanessa, Msosa, Chimwemwe, Kwatiwani, Nelson Msiska (Kamuzu Central Hospital), Malaysia: Feng Yih Chai, Siti Mohd Desa Asilah, Khuzaimah Zahid Syibrah (Hospital Keningau), Pui Xin Chin, Nur Zulaika Riswan (Kajang Hospital), Hoong-Yin, Chong, Nora Abdul Aziz, Keat-Seong, Poh, Chu-Ann, Chai, Sandip Kumar (University Malaya Medical Centre), Mustafa Mohammed Taher, Dayang Nita Abdul Aziz, Reynu Rajan (Universiti Kebangsaan Malaysia Medical Centre UKMMC), Rokayah, Julaihi, Durvesh Lacthman Jethwani, Muhammad Taqiyuddin Yahaya, Nik Azim Nik Abdullah, Susan Wndy Mathew, Kuet Jun Chung, Milaksh Kumar Nirumal, Goh Ern Tze, R., Syed Abdul Wahhab Eusoffee Wan Ali (Sarawak General Hospital), Yiing Yee Gan, Jesse Ron Swire Ting (Hospital Sibu), Sii, Samuel S. Y., Kean Leong Koay, Yi Koon Tan, Alvin Ee Zhiun Cheah, Chui Yee Wong, Tuan Nur'Azmah Tuan Mat, Crystal Yern Nee Chow, Har, Prisca A. L., Yishan Der (Hospital Sultanah Aminah), Yong Yong Tew, Fitjerald, Henry, Xinwei Low (Selayang Hospital), Ya Theng Neo, Hian Ee Heng, Shu Ning Kong, Cheewei, Gan, Yi Ting Mok, Yee Wen Tan, Kandasami, Palayan, Mahadevan Deva Tata, Yih Jeng Cheong (Hospital Tuanku Ja'afar), Kuhaendran, Gunaseelan, Wan Nurul 'Ain Wan Mohd Nasir, Pigeneswaren Yoganathan (Hospital Keningau), Eu Xian Lee, Jian Er Saw, Li Jing Yeang, Pei Ying Koh, Shyang Yee Lim, Shuang Yi Teo (Hospital Pulau Pinang, / Penang Medical College), Malta: Nicole Grech, Daniela, Magri, Kristina, Cassar, Christine, Mizzi, Malcolm, Falzon, Nihaal, Shaikh, Ruth, Scicluna, Stefan, Zammit, Sean, Mizzi, Svetlana Doris Brincat, Thelma, Tembo, Vu Thanh Hien Le, Tara, Grima, Keith, Sammut, Kurt, Carabott, Ciskje, Zarb, Andre, Navarro, Thea, Dimech, Georgette Marie Camilleri, Isaac, Bertuello, Jeffrey, Dalli, Karl Bonavia (Mater Dei Hospital), Mexico: Samantha Corro-Diaz, Marisol, Manriquez-Reyes, Antonio Ramos-De la Medina (Hospital Español de Veracruz), Morocco: Amina Abdelhamid, Abdelmalek, Hrora, Sarah, Benammi, Houda, Bachri, Meryem, Abbouch, Khaoula, Boukhal, Redouane Mammar Bennai, Abdelkader, Belkouchi, Mohamed Sobhi Jabal, Chaymae Benyaiche (IBN Sina Hospital) Netherlands: Maarten Vermaas, Lucia Duinhouwer (Ijsselland Hospital) Nicaragua: Javier Pastora, Greta, Wood, Maria Soledad Merlo (Hospital Escuela Oscar Danilo Rosales Arguello), Nigeria: Akinlabi Ajao, Omobolaji, Ayandipo, Taiwo, Lawal, Abdussemiu Abdurrazzaaq (University College Hospital, Ibadan), Muslimat, Alada, Abdulrasheed, Nasir, James, Adeniran, Olufemi, Habeeb, Ademola Adeyeye (University Of Ilorin Teaching Hospital, Ilorin), Ademola, Adebanjo, Adewale Adeniyi (Federal Medical Centre, Abeokuta, ), Henry, Mendel, Bashir, Bello, Umar Muktar (Usmanu Danfodiyo University Teaching Hospital), Thomas Olagboyega Olajide, Oyindamola, Oshati, George, Ihediwa, Babajide, Adenekan, Victor, Nwinee, Abdulrazzaq, Lawal, Chris, Bode, Mojolaoluwa Olugbemi (Lagos University Teaching Hospital), Oluwatomi, Odutola, Oluwaseyi, Adebola, Clement, Onuoha, Fatai, Balogun, Olalekan, Ajai, Iloba, Njokanma, Roland Osuoji (Lagos State University Teaching Hospital), Stephen, Kache, Jonathan, Ajah, Jerry Makama (Barau Dikko Teaching Hospital, Kaduna State University, Kaduna), Ahmed, Adamu, Suleiman, Baba, Mohammad, Aliyu, Shamsudeen, Aliyu, Yahaya, Ukwenya, Halima, Aliyu, Tunde, Sholadoye, Muhammad, Daniyan, Oluseyi Ogunsua (Ahmadu Bello University Teaching Hospital Zaria), Abdurrahaman, Sheshe, Aminu Mohammad (Aminu Kano Teaching Hospital), Samson, Olori, Philip, Mshelbwala, Garba, Samson, Oyediran Kehinde Timothy, Sani Ali Samuel (University Of Abuja Teaching Hospital, Anthony, Ajiboye, Isaac, Amole, Olajide, Abiola, Akin Olaolorun (Bowen University Teaching Hospital), Norway: Kjetil Søreide, Torhild, Veen, Arezo, Kanani, Kristian, Styles, Ragnar, Herikstad, Johannes Wiik Larsen, Jon Arne Søreide (Stavanger University Hospital), Elisabeth, Jensen, Mads, Gran, Eirik Kjus Aahlin (University Hospital Of Northern Norway), Tina, Gaarder, Peter Wiel Monrad-Hansen, Pål Aksel Næss (Oslo University Hospital), Giedrius, Lauzikas, Joachim, Wiborg, Silje Holte (Sykehuset Telemark HF), Knut Magne Augestad, Gurpreet Singh Banipal, Thomas Tetens Moe, Johannes Kurt Schultz (Akershus University Hospital), Palestine: Taher Al-taher, Ayah, Hamdan, Ayman, Salman, Rana, Saadeh, Aseel, Musleh, Dana, Jaradat, Soha, Abushamleh, Sakhaa, Hanoun, Amjad Abu Qumbos, Aseel, Hamarshi, Ayman And Taher (Al Makassed Islamic Charitable Society Hospital, Jerusalem), Israa, Qawasmi, Khalid, Qurie, Marwa, Altarayra, Mohammad, Ghannam, Alaa, Shaheen, Azher Herebat (Alia Governmental Hospital), Aram, Abdelhaq, Ahmad, Shalabi, Maram, Abu-toyour, Fatema, Asi, Ala, Shamasneh, Anwar, Atiyeh, Mousa, Mustafa, Rula, Zaa'Treh, Majd Dabboor (Palestine Medical Complex), Enas, Alaloul, Heba, Baraka, Jehad, Meqbil, Alaa, Al-Buhaisi, Mohamedraed, Elshami, Samah, Afana, Sahar, Jaber, Said, Alyacoubi, Yousef Abuowda (Islamic University of Gaza Medical School, European Gaza Hospital &, Shifa, Hospital), Tasneem Idress, Eman Abuqwaider (Mizan hospital), Sara, Al-saqqa, Alaa, Bowabsak, Alaa El Jamassi, Doaa, Hasanain, Hadeel, Al-farram, Maram, Salah, Aya, Firwana, Marwa, Hamdan, Israa Awad (Al-Shifa Hospital), Ahmad Ashour, Fayez Elian Al Barrawi (Bit Hanoun Hospital), Ahmed, Al-khatib, Maha, Al-faqawi, Mohamed Fares (Nasser Hospital), Amjad, Elmashala, Mohammad, Adawi, Ihdaa Adawi (Beit Jala Governmental Hospital), Reem, Khreishi, Rose Khreishi (Martyr Thabet Govermental hospital, Tulkarem), Ahmad, Ashour, Ahed Ghaben (Indonesian Hospital, Gaza) Pakistan: Najwa Nadeem, Muhammad Saqlain (Allied Hospital, Faisalabad), Jibran, Abbasy, Abdul Rehman Alvi, Tanzeela, Gala, Noman Shahzad (Aga Khan University), Kamran Faisal Bhopal, Muhammad Talha Butt, Syed Asaat ul Razi, Asdaq, Ahmed, Ali Khan Niazi (Bahawal Victoria Hospital), Ibrahim, Raza, Fatima, Baluch, Ahmed, Raza, Ahmad, Bani-Sadar, Muhammad, Adil, Awais Raza (King Edward Medical University, Mayo, Hospital, Lahore), Mahnoor, Javaid, Muhammad, Waqar, Maryam Ali Khan (CMH Lahore Medical And Dental College), Mohammad Mohsin Arshad, Mohammadasim Amjad (Nishtar Medical College And Hospital), Paraguay: Gustavo Miguel Machain Vega, Jorge Torres Cardozo, Marcelo O´Higgins Roche, Gustavo Rodolfo Pertersen Servin, Helmut Alfredo Segovia Lohse, Larissa Ines Páez Lopez, Ramón Augusto Melo Cardozo (Hospital de Clínicas, II Cátedra de Clínica Quirúrgica, Universidad Nacional de Asunción) Peru: Fernando Espinoza, Angel David Pérez Rojas, Diana, Sanchez, Camila Sanchez Samaniego, Shalon Guevara Torres, Alexander Canta Calua, Cesar, Razuri, Nadia, Ortiz, Xianelle, Rodriguez, Nahilia, Carrasco, Fridiz, Saravia, Hector Shibao Miyasato, María, Valcarcel-Saldaña, Ysabel Esthefany Alejos Bermúdez, Juan, Carpio, Walter Ruiz Panez, Pedro Angel Toribio Orbegozo (Hospital Nacional Arzopispo Loayza), Carolina Guzmán Dueñas, Kevin Turpo Espinoza, Ana Maria Sandoval Barrantes, Jorge Armando Chungui Bravo, Lorena, Fuentes-Rivera, Carmen, Fernández, Bárbara, Málaga, Joselyn Ye (Hospital Cayetano Heredia), Ricardo Velasquez, Jannin Salcedo (Clínica De Especialidades Médicas), Ana Lucia Contreras-Vergara, Angelica Genoveva Vergara Mejia, Maria Soledad Gonzales Montejo (Hospital Nacional Guillermo Almenara Irigoyen), Marilia Del Carmen Escalante Salas, Willy Alcca Ticona, Marvin, Vargas, George Christian Manrique Sila, Robinson, Mas, Arazzelly del Pilar Paucar (Hospital Regional De Ayacucho), Armando José Román Velásquez, Alina, Robledo-Rabanal, Ludwing Alexander Zeta Solis (Hospital III José Cayetano Heredia), Kenny Turpo Espinoza (Hospital Nacional Maria Auxiliadora), José Luis Hamasaki Hamaguchi, Erick Samuel Florez Farfan, Linda Alvi Madrid Barrientos, Juan Jaime Herrera Matta (Hospital De Policia), Mora, Philippines: John Jemuel V., Redota, Menold Archee P., Manuel Francisco Roxas, Maño (The Medical City), Maria Jesusa B., Marie Dione Parreno-Sacdalan, Christel Leanne Almanon (Department Of Surgery, Philippine General Hospital, University Of The Philippines Manila), Poland: Maciej Walędziak, Rafał, Roszkowski, Michał Janik (Department Of General, Oncological, Metabolic And Thoracic Surgery, Military Institute Of Medicine, Warsaw), Anna, Lasek, Piotr, Major, Dorota, Radkowiak, Mateusz Rubinkiewicz (2nd Department Of Surgery, Jagiellonian University Medical College), Portugal: Cristina Fernandes, Renato Melo (Centro Hospitalar De São João), Romania: Liviu Muntean, Aurel Sandu Mironescu, Lucian Corneliu Vida (Spitalul Clinic De Copii Brasov), Amar Kourdouli, Mariuca Popa (Spital Judetean De Urgenta Din Craiova), Hogea Mircea (Spitalul Clinic Judetean Brasov), Mihaela, Vartic, Bogdan, Diaconescu, Matei Razvan Bratu, Ionut, Negoi, Cezar Ciubotaru (Emergency Hospital of Bucharest), Allen Ingabire, Rwanda: J. C., Norbert Uzabumwana (University Teaching Hospital Of Kigali), Dieudonne Duhoranenayo (Kibungo Hospital), San Marino: Elio Jovine, Nicola, Zanini, Giovanni Landolfo (San Marino State Hospital), Saudi Arabia: Murad Aljiffry, Faisal, Idris, Alghamdi, Mohammed Saleh A., Ashraf, Maghrabi, Aroub, Alkaaki, Sondos Turkustani (Department of Surgery, King Abdulaziz University Hospital, Jeddah) Eyad Khalifah, Adel, Albiety, Sarah, Sahel, Reham, Alshareef, Mohammed Najjar (Department of Surgery, King Abdulaziz University Hospital and Oncology Center, Jeddah) Ahmed Alzahrani, Ahmed, Alghamdi, Wedyan Alhazmi (King Fahad Hospital, Jeddah) Ghiath Al Saied, Mohammed, Alamoudi, Muhammed Masood Riaz (King Fahad Medical City, Mazen, Hassanain, Basmah, Alhassan, Abdullah, Altamimi, Reem, Alyahya, Norah Al Subaie, Fatema Al Bastawis, Roaa Khan (King Khaled University Hospital), Serbia: Milan Radojkovic, Ljiljana, Jeremic, Milica Nestorovic (Clinic For General Surgery, Clinical Center Nis), Singapore: Jia Hao Law, Keith Say Kwang Tan, Ryan Choon Kiat Tan, Joel Kin Tan, Lau Wen Liang Joel, Bettina, Lieske, Xue Wei Chan, Faith Qi Hui Leong, Choon Seng Chong, Sharon, Koh, Kai Yin Lee, Kuok Chung Lee (National University Hospital) South Africa: Kent Pluke, Britta, Dedekind, Puyearashid, Nashidengo, Mark Ian Hampton (Victoria Hospital Wynberg), Johanna, Joosten, Sanju, Sobnach, Liana, Roodt, Anthony, Sander, James, Pape, Richard Spence (Groote Schuur), Niveshni Maistry (Charlotte Maxeke Johannesburg Academic Hospital), Phumudzo, Ndwambi, Kamau, Kinandu, Myint Tun (Leratong Hospital), Frederick Du Toit, Quinn, Ellison, Sule, Burger, Grobler, Dc, Lawrence Bongani Khulu (Tembisa Tertiary Provincial Hospital), Rachel, Moore, Vicky, Jennings, Astrid Leusink (Chris Hani Baragwanath Academic Hospital), Nazmie, Kariem, Juan, Gouws, Kathryn, Chu, Heather, Bougard, Fazlin, Noor, Angela Dell (New Somerset Hospital), Stephanie Van Straten (Helen Joseph Hospital, University Of Witwatersrand), Arvin, Khamajeet, Serge Kapenda Tshisola, Kalangu Kabongo (Stanger Hospital), Yoshan, Moodley, Frank, Anderson, Thandinkosi Madiba (Inkosi Albert Luthuli Central Hospital), Flip du Plooy (Mediclinic Potchefstroom), Leila, Hartford, Gareth, Chilton, Parveen Karjiker (Mitchell's Plain District Hospital), Matlou Ernest Mabitsela, Sibongile Ruth Ndlovu (Dr George Mukhari Academic Hospital), Maria Badicel, Robert Jaich (Milpark Hospital) Spain: Jaime Ruiz-Tovar (University Hospital Rey Juan Carlos), Luis, Garcia-Florez, Otero-Díez, Jorge L., Virginia Ramos Pérez, Nuria Aguado Suárez (Hospital Universitario San Agustín), Javier Minguez García, Sara Corral Moreno, Maria Vicenta Collado, Virginia Jiménez Carneros, Javier García Septiem (Hospital Universitario de Getafe), Mariana, Gonzalez, Antonio, Picardo, Enrique, Esteban, Esther, Ferrero, Irene Ortega (Infanta Sofía University Hospital), Eloy, Espin-Basany, Ruth, Blanco-Colino, Valeria Andriola (Hospital Valle De Hebron), Elisa, Contreras, Carmen García Bernardo, Sandra, Sanz, Alberto Miyar de León, Asnel, Dorismé, Joseluis, Rodicio, Aida, Suarez, Jessica, Stuva, Tamara Diaz Vico (Central University Hospital Of Asturias), Laura, Fernandez-Vega, Carla, Soldevila-Verdeguer, Fatima, Sena-Ruiz, Natalia, Pujol-Cano, Paula, Diaz-Jover, José Maria Garcia-Perez, Juan Jose Segura-Sampedro, Cristina, Pineño-Flores, David, Ambrona-Zafra, Andrea, Craus-Miguel, Patricia, Jimenez-Morillas, Angela Mazzella (Hospital Universitario Son Espases), B Jayathilake, Sri Lanka: A., Thalgaspitiya, S. P. B., Wijayarathna, L. S., Wimalge (University Surgical Unit, P. M. S. N., Teaching Hospital Anuradhapura), Kitts And Nevis: Hakeem Ayomi Sanni, St., Aliyu, Ndajiwo, Ogheneochuko Okenabirhie (Joseph, N France Hospital) Sudan: Anmar Homeida, Abobaker, Younis, Omer Abdelbagi Omer, Mustafa, Abdulaziz, Ali, Mussad, Ali Adam (University of Gezira), Sweden: Yucel Cengiz, Ida, Björklund, Sandra Ahlqvist (Sundsvall Hospital), Anders Thorell, Fredrik Wogensen (Ersta Hospital), Arestis Sokratous, Michaela Breistrand (Mora Hospital), Hildur Thorarinsdottir (Helsingborgs Lasarett), Johanna, Sigurdadottir, Maziar, Nikberg, Abbas Chabok (Västmanlands Hospital Västerås), Maria Hjertberg (Department Of Surgery And Department Of Clinical And Experimental Medicine, Linköping, University, Norrköping, Sweden), Peter, Elbe, Deborah, Saraste, Wiktor, Rutkowski, Louise Forlin (Karolinska Universitetssjukhuset, Solna), Karoliina, Niska, Malin Sund (Umea University Hospital) Switzerland: Dennis Oswald, Georgios, Peros, Rafael, Bluelle, Katharina, Reinisch, Daniel, Frey, Adrian Palma (Gzo Spital Wetzikon), Lucius, Zumbühl, Markus Zuber (Kantonsspital Olten), Roger Schmid, Gabriela Werder (Buergerspital Solothurn), Antonio, Nocito, Silke Mahanty (Kantonsspital Baden), Lukas Werner Widmer, Julia, Müller, Alissa Gübeli (Hospital Davos), Grzegorz Zuk (Gzo Spital Wetzikon), Turkey: Osman Bilgin Gulcicek, Yuksel, Altinel, Talar Vartanoglu (Bagcilar Research And Training Hospital), Emin, Kose, Servet Rustu Karahan, Mehmet Can Aydin (Okmeydanı Training And Research Hospital), Nuri Alper Sahbaz, Ilkay, Halicioglu, Sadi Konuk Training And Research Hospital), Halil Alis (Bakirkoy Dr., Ipek, Sapci, Can, Adıyaman, Ahmet Murat Pektaş, Turgut Bora Cengiz, Ilkan, Tansoker, Vedatcan, Işler, Muazzez, Cevik, Deniz, Mutlu, Volkan, Ozben, Berk Baris Ozmen, Sefa, Bayram, Sinem, Yolcu, Berna Buse Kobal, Ömer Faruk Toto, Haluk Cem Çakaloğlu (Acibadem University School of Medicine, Atakent, Hospital), Kagan, Karabulut, Vahit, Mutlu, Bahar Busra Ozkan (Ondokuz Mayis University Medical Faculty), Saban, Celik, Anil, Semiz, Selim, Bodur, Enisburak, Gül, Busra, Murutoglu, Reyyan, Yildirim, Bahadir Emre Baki, Ekin, Arslan, Mehmet, Ulusahin, Ali Guner (Karadeniz Technical University Faculty Of Medicine), United Kingdom: Nathan Walker, Nikhita, Shrimanker, Simon Cole (Royal United Hospital Bath), Ryan Breslin, Ravi Srinivasan (Blackpool Victoria Hospital), Kristina, Hunter, Ahmed Al-Bahrani (Watford General Hospital), Nora Grace Mairs, Alistair, Rocke, Lachlan, Dick, Mobeen Qureshi (Inverclyde Royal Hospital), Debkumar Chowdhury (University Hospital Ayr), Naomi, Wright, Clare, Skerritt, Thomas' Hospitals), Dorothy Kufeji (Guy's And St., Adrienne, Ho, Tharindra, Dissanayake, Athula, Tennakoon, Wadah Ali (Pilgrim Hospital, United Lincolnshire Hospitals NHS Trust), Charlene, Tan, Catrin Jones (Victoria Hospital Kirkcaldy), Stephen, Knight, Dima, Nassif, Abhishek Sharma (Perth Royal Infirmary), Oliver, Warren, Rebecca, White, Aia, Mehdi, Nathan, Post, Eliana, Kalakouti, Enkhbat, Dashnyam, Frederick Stourton (Chelsea And Westminster Hospital), Ioannis Mykoniatis, Chelise Currow (Northampton General Hospital), Francisca, Wong, Ashish, Gupta, Veeranna Shatkar (Queen's Hospital, BHR University Hospitals NHS Trust), Suraj, Kadiwar, Alexander Smedley (North Middlesex University Hospital), Rebecca, Wakefield, Philip, Herrod, James, Blackwell, Jonathan Lund (Royal Derby Hospital), Fraser, Cohen, Ashwath, Bandi, Stefano Giuliani (St George's Hospital), Giles, Bond-Smith, Neda, Farhangmehr, Miklos Perenyei (John Radcliffe Hospital, Oxford), Philip, Ireland, Kirk, Bowling, David Bunting (Gloucestershire Royal Hospital), Lydia, Longstaff, Kenneth Keogh (Royal Devon &, Exeter, Hospital), Hyunjin, Jeon, Muhammad Rafaih Iqbal, Shivun, Khosla, Anna, Jeffery, James Perera (Maidstone &, Tunbridge Wells NHS Trust), Ella Teasdale (Western Isles Hospital), Tariq, Alhammali, Yahya Salama (Kettering General Hospital NHS Trust), Rakan Kabariti, Shaun Oram (Nevill Hall Hospital), Thomas, Kidd, Fraser, Cullen, Christopher, Owen, Michael, Wilson, Seehui, Chiu, Hannah Sarafilovic (Ninewells Hospital), Jennifer, Ploski, Elizabeth, Evans, Athar, Abbas, Sylvia, Kamya, Norzawani, Ishak, Carly, Bisset, Cedar, Andress, Ye Ru Chin (Royal Alexandra Hospital, Paisley), Priya, Patel, David Evans (University Hospital, Wales), Anna Jeffery, James Perera (Maistone and Tunbridge Wells NHS Trust), Aidan, Haslegrave, Adam, Boggon, Kirsten, Laurie, Thomas Mann (Borders General Hospital), Anahita, Mansuri, Rachel, Davies, Ewen Griffiths (University Hospitals Birmingham NHS Trust), Aized Raza Shahbaz, Calvin, Eng, Farhat, Din, Ariadne, L'Heveder, Park, Esther H. G., Ramanish, Ravishankar, Kirsten, Mcintosh, Jih Dar Yau, Luke, Chan, Susan McGarvie (Western General Hospital, Edinburgh), Lingshan, Tang, Hui, Lim, Suhhuey, Yap, Jay, Park, Zhan Herr Ng, Shahrukh, Mirza, Yun Lin Ang, Luke, Walls, Chloe, Roy, Simon, Paterson-Brown, Julian, Camilleri-Brennan, Kenneth, Mclean, Michelle, S D'Souza, Savva, Pronin, David Ewart Henshall, Eunice Zuling Ter (Royal Infirmary Of Edinburgh), Dina Fouad, Ashish Minocha (Norfolk And Norwich University Hospital), William, English, Catrin, Morgan, Dominic, Townsend, Laura, Maciejec, Shareef, Mahdi, Onyinye, Akpenyi, Elisabeth, Hall, Hanaan, Caydiid, Zakaria, Rob, Tom, Abbott, Hew, D Torrance (The Royal London Hospital), Gareth Irwin, Robin Johnston (Ulster Hospital Dundonald), Mohammed Akil Gani, Gianpiero Gravante (Leicester Royal Infirmary), Shivanchan, Rajmohan, Kiran, Majid, Christopher Smith (West Middlesex University Hospital), Madanmohan, Palliyil, Sanjay, Patel, Luke, Nicholson, Neil, Harvey, Katie, Baillie, Sam, Shillito, Suzanne, Kershaw, Rebecca, Bamford, Peter Orton (Stockport NHS Foundation Trust), Elke, Reunis, Wai Cheong Soon (Good Hope Hospital), Jama, Guled M., Dharminder, Dhillon, Khyati Patel (Walsall Manor Hospital, Walsall), Shayanthan, Nanthakumaran, Rachel, Heard, Kar Yan Chen (Aberdeen Royal Infirmary), Behrad, Barmayehvar, Uttaran, Datta, Sivesh, K Kamarajah, Sharad Karandikar (Heartlands Hospital), Sobhana Iftekhar Tani (Nottingham University Hospital NHS Trust), Philippa, Donnelly, Michael Walker (Raigmore Hospital), Jehangirshaw, Parakh, Sarah, Blacker, Anil Kaul (Whiston Hospital), Arjun Paramasivan (Darlington Memorial Hospital), Sameh, Farag, Ashrafun, Nessa, Salwa Awadallah (Worthing Hospital, Western Sussex Hospital NHS Foundation Trust), Jieqi, Lim, James Chean Khun Ng (Queen Elizabeth University Hospital, Glasgow), United States: Katherine Gash, Kiran, Ravi P., Alice Murray (New York Presbyterian Hospital, / Columbia University Medical Center), Mohini, Dasari, Juan Puyana (University Of Pittsburgh Medical Center, - Presbyterian), Nadeem, Haddad, Martin, Zielinski, Asad Choudhry (Mayo Clinic), Celeste, Caliman, Mieshia, Beamon, Therese Duane (John Peter Smith Hospital), Ragavan Narayanan, Mamta Swaroop (Northwestern Memorial Hospital / Northwestern University), Jonathan, Myers, Rebecca, Deal, Erik Schadde (Rush University Medical Centre), Mark, Hemmila, Kathleen To (University Of Michigan Medical Center) Zambia: Alex Makupe, Joseph, Musowoya, Mayaba Maimbo (Ndola Central Hospital), Niels Van Der Naald, Dayson, Kumwenda, Alex, Reece-Smith, Kars, Otten, Anna, Verbeek, Marloes Prins (St Francis Mission Hospital) Data validators (GlobalSurg-2) Argentina: Alibeth Andres Baquero Suarez (Simplemente Evita), Ruben Balmaceda (Hospital Lagomaggiore), Barbados: Chelsea Deane (Queen Elizabeth Hospital), Croatia: Emilio Dijan (Zadar General Hospital), Egypt: Mahmoud Elfiky (Kasr Al Ainy Faculty of Medicine, Cairo University), Finland: Laura Koskenvuo (Helsinki University Hospital), France: Aurore Thollot (CHU Poitiers), Bernard Limoges (CHU Limoges), Carmen Capito (Hopital Necker Enfants Malades, Challine Alexandre (Hopital Cochin, Henri Kotobi (Trousseau Hospital, Julien Leroux (CHU Rouen), Kalitha Pinnagoda (CHU Toulouse), Nicolas Henric (CHU Angers), Olivier Azzis (CHU Rennes), Olivier Rosello (CHU Nice), Poddevin Francois (GHICL), Sara Etienne (CHU Saint Etienne), Philippe Buisson (CHU Amiens Picardie), Sophian Hmila (Hopital Robert Ballanger, Ghana: Joe-Nat Clegg-Lamptey (Korle Bu Teaching Hospital), Osman Imoro (Baptist Medical Centre), Owusu Emmanuel Abem (Komfo Anokye Teaching Hospital), Paul Wondoh (Upper West Regional Hospital), Greece: Dimitrios Papageorgiou (Naval And Veterans Hospital Of Athens), Vasiliki Soulou (Anticancer Hospital Of Athens Agios Savvas), Guatemala: Sabrina Asturias (Hospital Herrera Llerandi Amedesgua), Lenin Peña (Hospital General San Juan De Dios), India: Basant Kumar (Sanjay Gandhi Post Graduate Institute Of Medical College Lucknow), Ireland: Donal B O’Connor (Tallaght Hospital, Trinity College Dublin), Italy: Alberto Realis Luc (Santa Rita Clinic, Alfio Alessandro Russo (Treviglio Hospital), Andrea Ruzzenente (Azienda Ospedaliera Universitaria Integrata di Verona), Antonio Taddei (Azienda Ospedaliera Universitaria Careggi), Camilla Cona (IOV, - Istituto Oncologico Veneto), Corrado Bottini (Sant'Antonio Abate Hospital, Giovanni Pascale (Azienda Ospedaliero-Universitaria di Ferrara), Giuseppe Rotunno (Nicola Giannettasio Hospital, Leonardo Solaini (University Of Brescia, Spedali Civili Di Brescia, ), Marco Maria Pascale (Fondazione Policlinico Universitario 'Agostino Gemelli', ), Margherita Notarnicola (University Of Bari 'Aldo Moro'), Mario Corbellino (Ospedale Luigi Sacco Milano), Michele Sacco (Federico II University of Naples), 5 'Friuli Occidentale', Paolo Ubiali (Azienda per L'Assistenza Sanitaria N., Pordenone), Roberto Cautiero (Second University Of Naples), Tommaso Bocchetti (Sant’Andrea Hospital, Andrea Hospital, Elena Muzio (S., Vania Guglielmo (Policlinico Umberto I, Emergency Surgery Department), Eugenio Morandi (Ospedale di Rho, – ASST Rhodense), Patrizio Mao (San Luigi Gonzaga Hospital, Orbassano), Emilia De Luca (Department of Medical and Surgical Sciences, Jordan: Farah Mahmoud Ali (Jordan University Hospital), Margherita Notarnicola (Azienda Ospedaliero Universitaria Consorziale Policlinico Di Bari)., Lithuania: Justas Žilinskas (Klaipeda Republic), Kestutis Strupas (Vilnius University Hospital), Paulius Kondrotas (Taurage County Hospital), Robertas Baltrunas (Rokiskis District Municipality Hospital), Juozas Kutkevicius (Department Of General Surgery, Lithuanian University Of Health Sciences), Povilas Ignatavicius (Hospital Of Lithuanian University Of Health Sciences Kaunas Clinics), Malaysia: Choy Ling Tan (Hospital Sultanah Aminah), Jia Yng Siaw (Hospital Sibu), Sir Young Yam (Penang Medical College), Ling Wilson (Sarawak General Hospital), Mohamed Rezal Abdul Aziz (University Malaya Medical Centre), Malta: John Bondin (Mater Dei Hospital), Mexico: Carmina Diaz Zorrilla (Hospital Espanol De Veracruz), Morocco: Anass Majbar (Centre Hospitalier Ibn Sina Rabat), Nigeria: Danjuma Sale (Barau Dikko Teaching Hospital), Lawal Abdullahi (Aminu KanoTeaching Hospital), Olabisi Osagie (University Of Abuja Teaching Hospital), Omolara Faboya (Lagos State Teaching Hospital), Adedeji Fatuga (Lagos University Teaching Hospital), Agboola Taiwo (Babcock University Teaching Hospital), Emeka Nwabuoku (Ahmadu Bello University Teaching Hospital), Norway: Marte Bliksøen (Oslo University Hospital), Pakistan: Zain Ali Khan (Bahawal Victoria Hospital, Bahawalpur), Paraguay: Jazmin Coronel (Hospital de Clínicas, Universidad Nacional de Asunción) Peru: Cesar Miranda (Hospital Nacional Cayetano Heredia), Idelso Vasquez (Lima Almenara), Helguero-Santin (Hospital Regional III Jose Cayetano Heredia – Piura), Luis M., Rwanda: Jennifer Rickard (Centre Hospitalier Universitaire De Kigali), Romania: Aurel Mironescu (Spitalul Clinic De Copii Brasov), Saint Kitts and Nevis: Adesina Adedeji (Joseph, N France Hospital), Saudi Arabia: Saleh Alqahtani (King Fahad General Hospital), South Africa: Max Rath (Groote Schuur Hospital), Michael Van Niekerk (New Somerset Hospital), Modise Zacharia Koto (Dr George Mukhari Academic Hospital), Roel Matos-Puig (Stanger Hospital), Sweden: Leif Israelsson (Sundsvall), Switzerland: Tobias Schuetz (Kantonsspital Olten), Turkey: Mahmut Arif Yuksek (Ondokuz Mayis University), Meric Mericliler (Acibadem University School of Medicine, Mehmet Uluşahin (Karadeniz Technical University Farabi Hospital), United Kingdom: Bernhard Wolf (Raigmore Hospital Inverness), Cameron Fairfield (Royal Infirmary Of Edinburgh), Guo Liang Yong (Perth Royal Infirmary), Katharine Whitehurst (Royal Devon And Exeter), Michael Wilson (Ninewells Hospital And Medical School), Natalie Redgrave (John Radcliffe Hospital, Caroluce, K Musyoka (Royal Alexandra Hospital), James Olivier (Royal United Hospital Bath), Kathryn Lee (Queen Elizabeth Birmingham), Michael Cox (Royal Derby Hospital), Muhamed M, H Farhan-Alanie (Inverclyde Royal Hospital), Rory Callan (North Middlesex University Hospital) Zambia: Chali Chibuye (Ndola Central Hospital) Protocol translators (GlobalSurg-2) Arabic, Tebian Hassanein Ahmed Ali, Syrine, Rekhis, Muna, Rommaneh, Oday, Halhouli, Chinese, Zi Hao Sam, Jacky Hong Chieh Chen, French, Dylan, Roi, Greek, Vasileios Kalles, Italian, Gabriela Elisa Nita, Portuguese, Thays Brunelli Pugliesi, Gabriel, Pardo, Spanish, Ruth, Blanco, Eugenio Grasset, Escobar., Gallo, Gaetano, Adisa, A. O., Costas-Chavarri, A., Allen-Ingabire, J. C., Lilford, R. J., Harrison, E. M., Pinkney, T. D., Verjee, A., Runigamugabo, E., Altamini, A., Borda-Luque, G., Cornick, J., Fitzgerald, J. E., Kirby, A., Mihaljevic, A. L., Morton, D., Ntirenganya, F., Ots, R., Shaw, C. A., Khatri, C., Gobin, N., Freitas, A. V., Hall, N., Kim, S. -H., Negida, A., Jaffry, Z., Chapman, S. J., Arnaud, A. P., Tabiri, S., Recinos, G., Manipal, C. E., Mohan, M., Amandito, R., Shawki, M., Hanrahan, M., Zilinskas, J., Roslani, A. C., Goh, C. C., Ademuyiwa, A. O., Irwin, G., Shu, S., Luque, L., Shiwani, H., Altamimi, A., Alsaggaf, M. U., Spence, R., Rayne, S., Jeyakumar, J., Raptis, D. A., Glasbey, J. C., Modolo, M. M., Iyer, D., King, S., Arthur, T., Nahar, S. N., Waterman, A., Walsh, M., Agarwal, A., Zani, A., Firdouse, M., Rouse, T., Liu, Q., Correa, J. C., Salem, H. K., Talving, P., Worku, M., Kalles, V., Kumar, B., Kumar, S., Quek, R., Pata, F., Ansaloni, L., Altibi, A., Venskutonis, D., Poskus, T., Whitaker, J., Msosa, V., Tew, Y. Y., Farrugia, A., Borg, E., Ramos-De La Medina, A., Bentounsi, Z., Soreide, K., Gala, T., Al-Slaibi, I., Tahboub, H., Alser, O. H., Romani, D., Major, P., Mironescu, A., Bratu, M. R., Kourdouli, A., Ndajiwo, A., Altwijri, A., Gudal, A., Jubran, A. F., Seisay, S., Lieske, B., Ortega, I., Senanayake, K. J., Abdulbagi, O., Altinel, Y., Kong, C., Teasdale, E., Stoddart, M., Kabariti, R., Suresh, S., Gash, K., Narayanan, R., Maimbo, M., Fermani, C., Macdermid, E., Chenn, R., Yong, C. O., Edye, M., Jarmin, M., D'Amours, S. K., Youssef, D., Phillips, N., Brown, J., George, R., Koh, C., Warren, O., Hanley, I., Dickfos, M., Nawara, C., Ofner, D., Primavesi, F., Mitul, A. R., Mahmud, K., Hussain, M., Hakim, H., Kumar, T., Oosterkamp, A., Assouto, P. A., Lawani, I., Souaibou, Y. I., Tun, A. K., Chong, C. L., Devadasar, G. H., Qadir, M. R. M., Aung, K. P., Yeo, L. S., Castillo, V. D. P., Munhoz, M. M., Moreira, G., De Castro Segundo, L. C. B., Ferreira, S. A. K., Careta, M. C., Kim, S. B., De Sousa, A. V., Cury, A. D. L., Miguel, G. P. S., De Freitas, A. V. C., Silvestre, B. P., Vianna, J. G. P., Felipe, C. O., Laufer, L. A. V., Altoe, F., Da Silva, L. A., Pimenta, M. L., Giuriato, T. F., Morais, P. A. B., Luiz, J. S., Araujo, R., Menegussi, J., Leal, M., De Lima, C. V. B., Tatagiba, L. S., Leal, A., Dos Santos, D. V., Fraga, G. P., Simoes, R. L., Stock, S., Nigo, S., Kabba, J., Ngwa, T. E., Azzie, G., Kushwaha, S., Bailey, K., Cameron, B., Livingston, M., Horobjowsky, A., Deckelbaum, D. L., Razek, T., Marinkovic, B., Grasset, E., D'Aguzan, N., Jimenez, J., Macchiavello, R., Zhang, Z., Guo, W., Oh, J., Zheng, F., Montes, I., Sierra, S., Mendez, M., Villegas, M. I., Arango, M. C. M., Mendoza, I., Aristizabal, F. A. N., Botero, J. A. M., Riaza, V. M. Q., Restrepo, J., Morales, C., Cruz, H., Munera, A., Karlo, R., Domini, E., Mihanovic, J., Radic, M., Zamarin, K., Pezelj, N., Hache-Marliere, M., Lemaire, S. B., Rivas, R., Khyrallh, A., Hassan, A., Shimy, G., Fahmy, M. A. B., Nabawi, A., Elfil, M., Ghoneem, M., Gohar, M. E. S. A. M., Asal, M., Abdelkader, M., Gomah, M., Rashwan, H., Karkeet, M., Gomaa, A., Hasan, A., Elgebaly, A., Saleh, O., Fattah, A. A., Gouda, A., Elshafay, A. E., Gharib, A., Menshawy, A., Hanafy, M., Al-Mallah, A., Abdulgawad, M., Baheeg, M., Alhendy, M., Fattah, I. A., Kenibar, A., Osman, O., Gemeah, M., Mohammed, A., Adel, A., Sayed, A., Abozaid, M., El-Badri Kotb, A. H., Ata, A. A. A., Nasr, M., Alkammash, A., Saeed, M., El Hamid, N. A., Attia, A. M., El Galeel, A. A., Elbanby, E., El-Dien, K. S., Hantour, U., Alahmady, O., Mansour, B., Elkorashy, A. M., Taha, E. M. S., Lasheen, K. T., Elkolaly, S. S., Abdel-Wahab, N. Y. E., Abozyed, M. A. F., Saeed, A. M., El Sayed, G. S., Youssif, J. H., Ahmed, S. M., El-Shahat, N. S., Khedr, A. E. R. H., Elsebaaye, A. O., Elzayat, M., Abdelraheim, M., Elzayat, I., Warda, M., El Deen, K. N., Elnemr, A. E., Salah, O., Abbas, M., Rashad, M., Elzayyat, I., Hemeda, D., Tawfik, G., Salama, M., Khaled, H., Seisa, M., Elshaer, K., Hussein, A., Elkhadrawi, M., Afifi, A. M., Ebrahim, O. S., Metwally, M. M., Elmelegy, R., Elsawahly, D. M. E., Safa, H., Nofal, E., Elbermawy, M., Ghazy, A. A., Samih, H., Abdelgelil, A., Abdelghany, S., Kholy, A. E., Aboraya, M., Elkady, F., Salma, M., Samy, S., Fakher, R., Aboarab, A., Samir, A., Sakr, A., Haroun, A., Al-Aarag, A. A. R., Elkholy, A., Elshanwany, S., Ghanem, E., Tammam, A., Hammad, A. M., Shoura, Y. E., Ashal, G. E., Antar, S., Mehrez, S., Abdelshafy, M., Hamad, M. G. M., Hosh, M., Abdallah, E., Magdy, B., Alzayat, T., Gamaly, E., Elfeki, H., Abouzahra, A., Elsheikh, S., Elgendy, F. I., El-Salam, F. A., Seifelnasr, O., Ammar, M., Eysa, A., Sadek, A., Toeema, A. G., Nasr, A., Abuseif, M., Zidan, H., Barakat, S. A. E., Elsayed, N., Elrasoul, Y. A., Elkelany, A., Ammar, M. S., Mustafa, M. -A., Hegazy, Y., Etman, M., Saad, S., Alrahawy, M., Raslan, A., Morsi, M., Rslan, A., Sabry, A., Elwakil, H., Shaker, H., Abd-Elrasoul, Y., El-Kashef, H., Shaalan, M., Tarek, A., Elwan, A., Nayel, A. R., Seif, M., Emadeldin, D., Ghonaim, M. A., Almallah, A., Fouad, A., Sayma, E. A., Elbatahgy, A., El-Ma'doul, A. S., Mosad, A., Tolba, H., Elsorogy, D. E. A. A., Mostafa, H. A., Omar, A. A., El Hameed, O. S. A., Lasheen, A., El Salam, Y. A., Morsi, A., Ismail, M., El-Badawy, H. A., Amer, M. A., El-Hamouly, A. S., Attallah, N. A., Mosalum, O., Afandy, A., Mokhtar, A., Abouelnasr, A., Ayad, S., Shaker, R., Sakr, R., Amreia, M., Elsobky, S., Mustafa, M., Magd, A. A. E., Marey, A., Hafez, A. T., Zalabia, M. F., Mohamed, M. M., Fadel, A., Ahmed, E. A., Ali, A., Alwafai, M. G., Dwydar, A., Kharsa, S., Mamdouh, E., El-Sheemy, H., Al Youssef, I., Aly, A. K., Aldalaq, A., Alnawam, E., Alkhabbaz, D., Saad, M., Hussein, S., Elazayem, A. A., Meshref, A., Elashmawy, M., Mousa, M., Nashaat, A., Ghanem, S., Elsayed, Z. M., Elwaey, A., Elkadsh, I., Darweesh, M., Mohameden, A., Hafez, M., Badr, A., Badwy, A., Slam, M. A. E., Elazoul, M., Al-Nahrawi, S., Eldamaty, L., Nada, F., Ameen, M., Hagar, A., Elsehimy, M., Dawoud, H., Mesery, S. E., Gendy, A. E., Abdelkareem, A., Marey, A. S., Allam, M., Shehata, S., Abozeid, K., Elshobary, M., Fahiem, A., Sarsik, S., Hashish, A., Zidan, M., Hashish, M., Aql, S., Elhendawy, A. O. A., Husseini, M., Kasem, E., Gheith, A., Elfouly, Y., Soliman, A. R., Ibrahim, Y., Elfouly, N., Fawzy, A., Rashid, M., Elsherbiny, A. S., Sieda, B., Badwi, N. M., Mohammed, M. M. H., Mohamed, O., Habeeb, M. A., Starr, N., Desta, S., Wondimu, S., Abebe, N. S., Thomas, E., Asele, F. A., Dabessa, D., Zerihun, A. B., Scalabre, A., Frade, F., Irtan, S., Graffeille, V., Gaignard, E., Alimi, Q., Graffieille, V., Abbo, O., Mouttalib, S., Bouali, O., Hervieux, E., Aigrain, Y., Botto, N., Faure, A., Fievet, L., Panait, N., Eyssartier, E., Schmitt, F., Podevin, G., Parent, V., Martin, A., Muller, C., Bonnard, A., Peycelon, M., Abantanga, F., Boakye-Yiadom, K., Bukari, M., Owusu, F., Awuku-Asabre, J., Bray, L. D., Lytras, D., Psarianos, K., Bamicha, A., Kefalidi, E., Gemenetzis, G., Dervenis, C., Gouvas, N., Agalianos, C., Kontos, M., Kouraklis, G., Karousos, D., Germanos, S., Marinos, C., Anthoulakis, C., Nikoloudis, N., Mitroudis, N., Estupinian, S., Forno, W., Azmitia, J. R. A., Cabrera, C. C. R., Guevara, R., Aguilera, M., Mendez, N., Mendizabal, C. A. A., Ramazzini, P., Urquizu, M. C., Tale, F., Soley, R., Barrios, E., Rodriguez, D. E. M., Velasquez, C. I. P., Merida, S. M. C., Regalado, F., Lopez, M., Siguantay, M., Prasad, S. S., Kirishnan, A., Gyanchandani, N., Kumar, B. S., Rangarajan, M., Bhat, S., Sreedharan, A., Kinnera, S. V., Reddy, Y., Venugopal, C., Mittal, A., Nadkarni, S., Lakshmi, H. N., Malik, P., Limaye, N., Pai, S., Jain, P., Khajanchi, M., Satoskar, S., Satoskar, R., Mahamood, A. B., Rahmawati, F. N., Mayasari, M., Al-Hasani, R. K. M. J., Al-Hameedi, H. I. I., Ibraheem, H. I., Al-Azraqi, I. A. A., Sabeeh, L., Kamil, R., Telfah, M. M., Rasendran, A., Sheehan, J., Kerley, R., Normile, C., Gilbert, R. W., Song, J., Dablouk, M., Mauro, L., Dablouk, M. O., Kielty, P., Marks, E., Gosling, S., Mccarthy, M., Mirghani, D., Naqvi, S. A., Wong, C. S., Chung, S., D'Cruz, R., Cahill, R., Gosling, S. G., Fahy, C., Cadogan, D. D., Powell, A., Clifford, C., Driscoll, A., Paul, S., Lee, C., Bowe, R., Hutch, W., Mohan, H., O'Neill, M., Mealy, K., Danelli, P., Bondurri, A., Maffioli, A., Pasini, M., Pata, G., Roncali, S., Silvani, P., Carlucci, M., Faccincani, R., Bonavina, L., Macchitella, Y., Ceriani, C., Tugnoli, G., Saverio, S. 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A., Karim, R., Haque, M., Faruq, A., Iftekhar, F., O'Shea, M., Padmore, G., Jonnalagadda, R., Litvin, A., Filatau, A., Paulouski, D., Shubianok, M., Shachykava, T., Khokha, D., Khokha, V., Djivoh, F., Ismail, L., Dossou, F., Seto, D. M., Gbessi, D. G., Noukpozounkou, B., Keke, K. R., Hodonou, F., Ahounou, E. Y. S., Alihonou, T., Denakpo, M., Ahlonsou, G., Bedada, A. G., Nsengiyumva, C., Kwizera, S., Barendegere, V., Choi, P., Jamal, L., Chen, T. -L., Yip, C., Zapata, F., Lanau, M. I. V., Restrepo, I. M., Giraldo, R. S. R., Youssef, M., Thabet, W., Sanad, A., Zaki, A., Abdel-Hameed, N., Mostafa, M., Omar, M. F. W., Ghanem, A., Denewar, A., Emara, E., Rashad, E., Elashry, R., Emile, S., Khafagy, T., Elhamouly, S., Elfarargy, A., Mohamed, A. M., Nagy, G. S., Esam, A., Elwy, E., Khallaf, S., Ibrahim, E., Saidbadr, A., Moustafa, A., Mohammed, A. E., Elgheriany, M., Abdelmageed, E., Raouf, E. A. A., Elbanby, E. S., Elmasry, M., Farahat, M. M., Mansor, E. Y., Hegazy, E. 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Richard, Gobin, Neel, Freitas, Ana Vega, Hall, Nigel, Kim, Sung‐Hee, Negida, Ahmed, Khairy, Hosni, Chapman, Stephen J, Arnaud, Alexis P, Manipal, Cutting Edge, Amandito, Radhian, Shawki, Marwan, Hanrahan, Michael, Zilinskas, Justa, Roslani, April Camilla, Goh, Cheng Chun, Irwin, Gareth, Luque, Laura, Shiwani, Hunain, Altamimi, Afnan, Alsaggaf, Mohammed Ubaid, Jeyakumar, Jenifa, Cengiz, Yucel, Raptis, Dmitri A, Modolo, Maria Marta, Iyer, Dushyant, King, Sebastian, Arthur, Tom, Nahar, Sayeda Nazmum, Waterman, Ade, Walsh, Michael, Agarwal, Arnav, Zani, Augusto, Firdouse, Mohammed, Rouse, Tyler, Liu, Qinyang, Correa, Juan Camilo, Talving, Peep, Worku, Mengistu, Arnaud, Alexi, Kalles, Vassili, Kumar, Basant, Kumar, Sunil, Quek, Roy, Ansaloni, Luca, Altibi, Ahmed, Venskutonis, Donata, Poskus, Toma, Whitaker, John, Msosa, Vanessa, Tew, Yong Yong, Farrugia, Alexia, Borg, Elaine, Bentounsi, Zineb, Gala, Tanzeela, Al‐Slaibi, Ibrahim, Tahboub, Haya, Alser, Osaid H., Romani, Diego, Shu, Sebestian, 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Vanessa Dina Palomino, Munhoz, Monique Moron, Moreira, Gisele, De Castro Segundo, Luiz Carlos Barro, Ferreira, Salim Anderson Khouri, Careta, Maíra Cassa, Kim, Stella Binna, De Sousa, Alexandre Venancio, Cury, Alyne Daltri Lazzarini, Miguel, Gustavo Peixoto Soare, De Freitas, Ana Vega Carreiro, Guasti, Barbara Pereira Silvestre Julia, Vianna, Pinto, Felipe, Carolina Oliveira, Laufer, Luis Alberto Valente, Altoe, Fernanda, Da Silva, Luana Ayre, Pimenta, Marina Luiza, Giuriato, Thiago Fernande, Morais, Paulo Alves Bezerra, Araujo, Jessica Souza Luiz Rafael, Menegussi, Juliana, Leal, Marisa, Lima, Caio Vinícius Barroso, Tatagiba, Luiza Sarmento, Leal, Antônio, Santos, Diogo Viniciu, Fraga, Gustavo Pereira, Simoes, Romeo Lage, Stock, Simon, Nigo, Samuel, Kabba, Juana, Ngwa, Tagang Ebogo, Brown, Jame, Azzie, George, Kushwaha, Sameer, Bailey, Karen, Cameron, Brian, Livingston, Michael, Horobjowsky, Alexandre, Deckelbaum, Dan L, Razek, Tarek, Marinkovic, Bori, Grasset, Eugenio, D'aguzan, 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Athar, Sadek, Aliaa, Toeema, Aliaa Gamal, Nasr, Aly, Abuseif, Mohamed, Zidan, Hagar, Barakat, Sara Abd Elmageed, Elsayed, Nadin, Elrasoul, Yasmin Abd, Elkelany, Ahmed, Ammar, Mohamed Sabry, Mustafa, Mennat‐Allah, Hegazy, Yasmin, Etman, Mohamed, Saad, Samar, Alrahawy, Mahmoud, Raslan, Ahmed, Morsi, Mahmoud, Rslan, Ahmed, Sabry, Ahmed, Elwakil, Hager, Shaker, Heba, Abd‐Elrasoul, Yasmin, El‐Kashef, Hussein, Shaalan, Mohamed, Tarek, Areej, Elwan, Ayman, Nayel, Ahmed Ragab, Seif, Mostafa, Emadeldin, Doaa, Ghonaim, Mohamed Ali, Almallah, Ahmad, Fouad, Ahmed, Sayma, Eman Adel, Elbatahgy, Ahmad, El‐Ma'doul, Angham Solaiman, Mosad, Ahmed, Tolba, Hager, Elsorogy, Diaa Eldin Abdelazeem Amin, Mostafa, Hassan Ali, Omar, Amira Atef, El Hameed, Ola Sherief Abd, Lasheen, Ahmed, El Salam, Yasser Abd, Morsi, Ashraf, Ismail, Mohammed, El‐badawy, Hager Ahmed, Amer, Mohamed A, El‐Hamouly, Ahmed Sabry, Attallah, Noura A., Mosalum, Omnia, Afandy, Ahmed, Mokhtar, Ahmed, Abouelnasr, Alaa, Ayad, Sara, Shaker, 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Rajan, Reynu, Chong, Hoong Yin, Agius, Marija, Bezzina, Maureen, Bugeja, Roberta, Vella‐Baldacchino, Martinique, Spina, Andrew, Psaila, Josephine, Francois‐Coridon, Helene, Tolg, Cecilia, Colombani, Jean‐Francoi, Diaz‐Zorrilla, Carmina, De La Medina, Antonio Ramos‐, Gonzalez, Samantha Corro‐Diaz, Jacobe, Mário, Mapasse, Domingo, Snyder, Elizabeth, Oumer, Ramadan, Osman, Mohammed, Mohammad, Aminu, Anyanwu, Lofty‐John, Sheshe, Abdulrahman, Adesina, Alaba, Faturoti, Olubukola, Taiwo, Ogechukwu, Ibrahim, Muhammad Habib, Nasir, Abdulrasheed A, Suleiman, Siyaka Itopa, Adeniyi, Adewale, Adesanya, Opeoluwa, Adebanjo, Ademola, Osuoji, Roland, Atobatele, Kazeem, Ogunyemi, Ayokunle, Williams, Omolara, Oludara, Mobolaji, Oshodi, Olabode, Ademuyiwa, Adesoji, Lawal, AbdulRazzaq Oluwagbemiga, Alakaloko, Felix, Elebute, Olumide, Osinowo, Adedapo, Bode, Christopher, Adesuyi, Abidemi, Tade, Adesoji, Adekoya, Adeleke, Nwokoro, Collin, Ayandipo, Omobolaji O, Lawal, Taiwo Akeem, Ajao, Akinlabi E, Ali, 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Pierina García, Barreda, Luis Miguel Alvarez, Ojeda, Ronald Renato Barrionuevo, Garaycochea, Octavio, Mollo, Melanie Castro, Delgado, Mitchelle Solange De Fã Tima Linare, Fujii, Francisco, Durand, Susana Yrma Aranzabal, Basto, Carlos Alejandro Arroyo, Rojas, Nelson Manuel Urbina, Yip, Sebastian Bernardo Shu, Vergara, Ana Lucia Contrera, Moran, Andrea Echevarria Rosa, Luque, Giuliano Borda, Castro, Manuel Rodriguez, Jaramillo, Ramon Alvarado, Sila, George Manrique, Lopez, Crislee Elizabeth, De Leon, Mardelangel Zapata Ponze, Machaca, Massiell, Huaraya, Ronald Coasaca, Arenas, Andy, López, Crislee, Puma, Clara Milagros Herrera, Pino, Wilfredo, Hinojosa, Christian, De Leon, Melanie Zapata Ponze, Limache, Susan, Sila, George Manrrique, Rodriguez, Layza‐Alejandra Mercado, Melo, Renato, Costa‐Maia, Jose, Muralha, Nuno, Sauvat, Frederique, Dan, Ionasc, Hogea, Mircea, Eduard, Pandi, Bratu, Razvan‐Matei, Beuran, Mircea, Diaconescu, Ionut‐Bogdan, Martian, Bogdan‐Valeriu, Iordache, Florin‐Mihail, Vartic, Mihaela, Vida, Lucian Corneliu, Muntean, Liviu Iuliu, Mironescu, Aurel Sandu, Nsengimana, Vizir Jean Paul, Niragire, Alice, Ingabire, Jean De La Croix Allen, Niyirera, Eugene, Zanini, Nicola, Jovine, Elio, Landolfo, Giovanni, Alomar, Ibrahim N., Alnuqaydan, Saleh A., Altwigry, Abdulrahman M., Othman, Moayad, Osman, Nohad, Alqahtani, Ena, Alzahrani, Mohammed, Alyami, Rifan, Aljohani, Emad, Alhabli, Ibrahim, Mikwar, Zaher, Almuallem, Sultan, Nawawi, Abrar, Bakhaidar, Mohamad, Maghrabi, Ashraf A., Alsaggaf, Mohammed, Aljiffry, Murad, Altaf, Abdulmalik, Khoja, Ahmad, Habeebullah, Alaa, Akeel, Nouf, Ghandora, Nashat, Almoflihi, Abdullah, Huwait, Abdulmalik, Al‐shammari, Abeer, Al‐Mousa, Mashael, Alghamdi, Masood, Adham, Walid, Albeladi, Bandar, Alfarsi, Muayad Ahmed, Mahdi, Atif, Al Awwad, Saad, Nouh, Thamer, Hassanain, Mazen, Aldhafeeri, Salman, Sadig, Nawal, Algohary, Osama, Aledrisy, Mohannad, Alrifaie, Ahmad, AlRowais, Mohammed, Althwainy, Amani, Shabkah, Alaa, Alamoudi, Uthman, Alrajraji, Mawaddah, Alghamdi, Basim, Aljohani, Saud, Daqeeq, Abdullah, Al‐Faifi, Jubran J, Jennings, Vicky, Ngayu, Nyawira, Moore, Rachel, Kong, Victor, Kretzmann, Hayden, Connor, Katie, Nel, Daniel, Sampson, Colleen, Panieri, Eugenio, Sishuba, Nosisa, Tun, Myint, Mphatsoe, Albert Mohale, Carreira, Jo‐Anne, Wagener, Mark, Botes, Stefan, Du Plessis, Danelo, Fernandez‐Bueno, Fernando, Aguilar‐Jimenez, Jose, Garcia‐Marin, Jose Andre, García, Lorena Solar, Florez, Luis Joaquín García, Pacheco, Rubén Darío Aria, Pagnozzi, Janet, Quezada, Jimy Harold Jara, Rodicio, Jose Lui, Minguez, German, Rodríguez‐Uría, Raquel, Ugalde, Paul, Lopez‐Arevalo, Camilo, Barneo, Lui, Stuva, Jessica Patricia Gonzale, Ortega‐Vazquez, Irene, Rodriguez, Lorena, Herrera, Norberto, Arachchi, Prasad Pitigala, Senanayake, Wanigasekara, Senanayake, Mudiyanselage Kithsiri Janakantha, Arachchige, Lalith Asanka Jayasooriya Jayasoori, Sivaganesh, Sivasuriya, Samaraweera, Dulan Irusha, Thanusan, Vimalakanthan, Musa, Ahmed Elgaili Khalid, Balila, Reem Mohammed Hassan, Mohamed, Mohamed Awad Elkarim Hamad, Ali, Hussein, Elabdin, Hagir Zain, Hassan, Alaa, Mahdi, Sefeldin, Ahmed, Hala, Idris, Sahar Abdoun Ishag, Elsayed, Makki, Elsayed, Mohammed, Mahmoud, Mohamed, Boijsen, Magnu, Lundgren, Per‐Olof, Gustafsson, Ulf, Kiasat, Ali, Wogensen, Fredrik, Jurdell, Emma, Thorell, Ander, Thorarinsdottir, Hildur, Utter, Maria, Sundstrom, Sami Martin, Wredberg, Cecilia, Kjellin, Ann, Nyberg, Johanna, Frisk, Bjorn, Sund, Malin, Andersson, Linda, Gunnarsson, Ulf, Cengiz, Yücel, Ahlqvist, Sandra, Björklund, Ida, Royson, Hanna, Weber, Per, Pahlsson, Hans‐Ivar, Borin, Eva, Hjertberg, Maria, Schmid, Roger, Schivo, Debora, Despotidis, Vasileio, Breitenstein, Stefan, Staerkle, Ralph F, Schadde, Erik, Deichsel, Fabian, Gerosa, Alexandra, Nocito, Antonio, Raptis, Dimitri Aristotle, Mijuskovic, Barbara, Zuber, Marku, Eisner, Luka, Kruspi, Swantje, Reinisch, Katharina Beate, Schoewe, Christin, Novak, Allan, Palma, Adrian F., Teufelberger, Gerfried, Kimaro, Msafiri, King, Rachel, Balkan, Ali Zeynel Abidin, Gumar, Mehmet, Yavuz, Mehmet Ali, Karabacak, Ufuk, Lap, Gokhan, Ozkan, Bahar Busra, Karakahya, Murat, Adams, Ryan, Morton, Robert, Henderson, Liam, Gratton, Ruth, Clement, Keiran David, Chang, Kate Yu‐Ching, Mcnish, David, Mcintosh, Ryan, Milligan, William, Skelly, Brendan, Anderson‐Knight, Hannah, Lawther, Roger, Onimowo, Jemina, Shatkar, Veereanna, Tharmalingam, Shivanee, Woin, Evelina, Fautz, Tessa, Ziff, Oliver, Dindyal, Shiva, Arman, Sam, Talukder, Shagorika, Gadhvi, Vijay, Chew, Luen Shaun, Heath, Jonathan, Blencowe, Natalie, Hallam, Sally, Mannu, Gurdeep Singh, Zachariades, Dimitris‐Christo, Snaith, Ailsa Claire, Hettiarachchi, Thusitha Sampath, Nesaratnam, Arjun, Wheeler, Jame, McCullagh, Darragh, Clements, Joshua Michael, Khan, Ata, Koumpa, Foteini, Neophytou, Christina, Roth, Jessica, Soon, Wai Cheong, Deputy, Mohammed, Ahmed, Ahmed, Ashton, Annelisse, Vincent, Joe, Almy, Jack, Khan, Taufiq, Allen, John Lee Y, Mcintyre, Charlotte Jane, Marshall, Dominic Charle, Sykes, Mark, Behar, Nebil, Jordan, Harriet, Rajjoub, Yaseen, Sherman, Thoma, White, Timothy, Watts, Anna, Ardley, Rohan, Arulampalam, Tan, Shah, Apar, Brown, Damien, Blower, Emma, Sutton, Paul, Gasteratos, Konstantino, Vimalachandran, Dale, Magee, Cathy, Mcguigan, Andrew, Mcaleer, Stephen, Morgan, Clare, Braungart, Sarah, Lafferty, Kirsten, Labib, Peter, Tanase, Andrei, Mangan, Clodagh, Reza, Lillian, Woodward, Helen, Gouldthorpe, Craig, Turner, Megan, Wild, Jonathan R L, Malik, Tom AM, Proctor, Victoria K, Hewage, Kalon, Davies, Jame, Dubois, Andre, Sarwary, Sayed, Zardab, Ali, Grant, Alan, Mcintyre, Robert, Mogan, Yogendra Praveen, Ho, Weiguang, Chong, Bryon Frankie Hon Khi, Tewari, Shirish, Humm, Gemma, Farinella, Eriberto, Hall, Nigel J, Wright, Naomi J, Major, Christina P, Xerri, Thelma, De Bono, Phoebe, Amin, Jasim, Farhad, Mustafa, Camilleri‐Brennan, John F., Robertson, Andrew G N, Swann, Joanna, Richards, Jame, Jabbar, Aijaz, Attard, Myranda, Burns, Hannah, Macdonald, Euan, Baldacchino, Matthew, Skehan, Jennifer, Camilleri‐Brennan, Julian, Hall, Tom Falconer, Gimzewska, Madelaine, Mclachlan, Greta, Shah, Jamie, Giles, Jame, Chiu, Selina, Weber, Beatrix, Chiu, Selina Man Yeng, Highcock, Saskia, Hassan, Maleeha, Beasley, William, Vlachogiorgos, Apostolo, Dias, Stephen, Maharaj, Geta, Mcdonald, Rosie, Macdonald, Alisdair, Witherspoon, Paul, Baird, Alan, Sarmah, Panchali, Green, Nikki, Youssef, Haney, Cross, Kate, Rees, Clare M, Van Duren, Bernard, Upchurch, Emma, Khan, Khurram, Abudeeb, Haytham, Hammad, Ahmed, Karandikar, Sharad, Bowley, Doug, Karim, Ahmed, Chachulski, Witold, Richardson, Liam, Dawnay, Gile, Thompson, Ben, Mistry, Ajayesh, Ghetia, Millika, Roy, Sudipta, Al‐Obaedi, Ossama, Das, Kaustuv, Prabhudesai, Ash, Cocker, DM, Tan, Jessica Juliana, Tyler, Robert, Di Franco, Filippo, Ayyar, Shruti, Vivekanantham, Sayinthen, Gokani, Shyam, Gillespie, Michael, Gudlaugsdottir, Katrin, Pezas, Theodore, Currow, Chelise, Kim, Matthew Young‐Han, Birring, Amerdip, Edwards, Joanne, Ali, Ased, Das, Suparna, Jha, Madan, Atkinson, Kieran, Luck, Joshua, Fozard, Thoma, Puttick, Michael, Salama, Yahya, Shah, Rohi, Ibrahem, Ahmad Aboelkassem, Ebdewi, Hamdi, Gravante, Gianpiero, El‐Rabaa, Saleem, Nnajiuba, Henry, Allott, Rebecca, Bhargava, Aman, Chan, Zoe, Hassan, Zaffar, Makinde, Misty, Hemingway, David, Dean, Ramzana, Boddy, Alexander, Aber, Ahmed, Patel, Vijay, Parakh, Jehangirshaw, Parthiban, Sunil, Ubhi, Harmony Kaur, Hosein, Simon‐Peter, Ward, Simon, Malik, Kamran, Jennings, Leifa, Newton, Tom, Alkhouri, Mirna, Kang, Min Kyu, Houlden, Christopher, Barry, Jonathan, Raza, Imtanan, Farquharson, Alistair, Bhattacharya, Sanjeet, Chang, Kate, Wilson, Michael S J, Neo, Yan Ning, Ibrahim, Ibrahim, Chan, Emily, Peck, Fraser S, Lim, Pei J, North, Alexander S, Blundell, Rebecca, Williamson, Adam, Fouad, Dina, Minocha, Ashish, Mccarthy, Kathryn, Court, Emma, Chambers, Alice, Yee, Jenna, Tham, Ji Chung, Beaton, Ceri, Walsh, Una, Lockey, Joseph, Bokhari, Salman, Howells, Lara, Griffiths, Megan, Yallop, Laura, Singh, Shailinder, Nasher, Omar, Jackson, Paul, Shariffuddin, Abdul Muiz, Ho, Weng Chee, Wilson, Michael Sj, Pabla, Gurpreet, Ramzi, Saed, Zeidan, Shady, Doughty, Jennifer, Sinha, Sidhartha, Davenport, Ro, Lewis, Jason, Duffy, Leo, Mcaleer, Elizabeth, Williams, Eleanor, Som, Robin, Javed, Omar, Boal, Matthew, Harrison, Nicola, Tafazal, Habib, Brogden, Tom, Griffiths, Ewen, Obute, Rhalumi Daniel, Glover, Thomas E, Clark, David J, Boshnaq, Mohamed, Akhtar, Mansoor, Capleton, Pascale, Doughan, Samer, Rabie, Mohamed, Mohamed, Ismail, Samuel, Duncan, Dickson, Lauren, Kennedy, Matthew, Dempster, Eleanor, Brown, Emma, Maple, Natalie, Monaghan, Eimear, Wolf, Bernhard, Garland, Alicia, Mcphee, Arthur, Anderson, David, Anderson, Robert, Hassan, Sarah, Smith, Dave, Lund, Jonathan, Boereboom, Catherine, Murphy, Jennifer, Tierney, Gillian, Tou, Samson, Zimmermann, Eleanor Franziska, Smart, Neil Jame, Warwick, Andrea Marie, Stasinou, Theodora, Daniels, Ian, Findlay‐Cooper, Kim, Mitrasinovic, Stefan, Ray, Swayamjyoti, Varcada, Massimo, D'Souza, Rovan, Omara, Sharif, Spurr, Matthew, Parkinson, Lucienne, Hanks, Anthony, Ma, Jennifer, Abington, Emily, Ramcharn, Meera, Williams, Gethin, Winstanley, Joseph, Kennedy, Ewan D., Yeung, Emily NW, Jones, Catrin, O'neill, Stephen, Lim, Shujing Jane, Liew, Ignatiu, Nair, Hari, Fairfield, Cameron, Oh, Julia, Koh, Samantha, Wilson, Andrew, Fairfield, Catherine, Anandkumar, Delran, Kirupagaran, Ashok, Jones, Timothy F, Torrance, Hew Dt, Fowler, Alexander J, Chandrakumar, Charmilie, Patel, Priyank, Ashraf, Syed Faaz, Lakhani, Sonam M., Mclean, Aaron Lawson, Basson, Sonia, Batt, Jeremy, Bowman, Catriona, Benons, Natasha, Mason, Clare, Harrison, Rebecca, Quayle, John, Barker, Tom, Summerour, Virginia, Harper, Edward, Smith, Caroline, Hampton, Matthew, Pitt, Sophie K, Ward, Alex E, O'Connor, Timothy, Heywood, Emily G, Chowdhury, Abeed, Hossaini, Sina, Watson, Nicholas F, Mckechnie, Doug, Farah, Ayaan, Chun, Anita, Koh, Hoey, Lim, Grace, Sunderland, Graham, Gould, Laura, Munipalle, P C, Rooney, H, Browning, D R L, Pereira, Bernadette, Nemeth, Kristof, Decker, Emily, Giuliani, Stefano, Shalaby, Aly, Shaikh, Shafaque, Tan, Chern Yan, Palkhi, Ebrahim Y A, Szczap, Aleksandra, Chidambaram, Swathikan, Chen, Chee Yang, Kulasabanathan, Kavian, Chhabra, Srishti, Kostov, Elisabeth, Harbord, Philippe, Barnacle, Jame, Palliyil, Madan Mohan, Zikry, Mina, Porter, Johnathan, Raslan, Charef, Hafiz, Shazia, Soltani, Niksa, Baillie, Katie, Singh, Priyanka, Sheth, Shailee, Patel, Kishen, Khalili, Mahry, Choi, Jeesoo, Benger, Matthew, Marples, Lucy, Macfarlane, Alastair, Thurairaja, Ramesh, Boyce, Tamsin, Whewell, Harriet, Jones, Elin, Th'ng, Francesca, Robertson, Nichola, Mirza, Ahmad, Saeed, Haroon, Galloway, Simon, Elena, Gia, Afzal, Mohammad, Zakir, Mohamed, Sodde, Peter, Hand, Charle, Sriram, Aiesha, Clark, Tamsyn, Holton, Patrick, Livesey, Amy, Sinha, Yashashwi, Iqbal, Fahad Mujtaba, Bharj, Indervir Singh, Rotundo, Adriana, Jenvey, Cara, Slade, Robert, Golding, David, Haines, Samuel, Ne'ma Abdullah, Ali Adel, Tilston, Thomas W, Loughran, Dafydd, Donoghue, Danielle, Giacci, Lorenzo, Sherif, Mohamed Ashur, Harrison, Peter, Tang, Alethea, Kotecha, Deevia, Elshaer, Mohamed, Urbonas, Toma, Riaz, Amjid, Chapman, Annie, Acharya, Parisha, Shalhoub, Joseph, Grossart, Cathleen, McMorran, David, Mlotshwa, Makhosini, Hawkins, William, Loizides, Sofroni, Krishna, Kandaswamy, Orchard, Melanie, Ho, Chik Wai, Thomson, Peter, Khan, Shahab, Taylor, Fiona, Shukla, Jalak, Howie, Emma Elizabeth, Macdonald, Linda, Komolafe, Olusegun, Mcintyre, Neil, Cragg, Jame, Parker, Jody, Stewart, Duncan, Lintin, Luke, Tracy, Julia, Farooq, Tahir, Molina, George, Kaafarani, Haytham, Beyene, Robel, Sava, Jack, Scott, Mark, Swaroop, Mamta, Kennedy, Raelene, Azodo, Ijeoma A, Heffernan, Daithi, Chun, Tristen, Stephen, Andrew, Sion, Melanie, Weinstein, Michael S., Punja, Viren, Bugaev, Nikolay, Goodstein, Monica, Razmdjou, Shadi, Etchill, Eric, Puyana, Juan Carlo, Kesinger, Matthew, Napolitano, Lena, To, Kathleen, Hemmila, Mark, Todd, Oliver, Jenner, Edward, Hoogakker, Ellen, Grizhja, Besmir, Ymeri, Shpetim, Galiqi, Gezim, Klappenbach, Roberto, Antezana, Diego, Beleño, Alvaro Enrique Mendoza, Costa, Cecilia, Sanchez, Belen, Aviles, Susan, Fermani, Claudio Gabriel, Balmaceda, Rubén, Villalobos, Santiago, Carmona, Juan Manuel, Hamill, Daniel, Deutschmann, Peter, Sandler, Simone, Cox, Daniel, Nataraja, Ram, Sharpin, Claire, Ljuhar, Damir, Gray, Demi, Haines, Morgan, Iyer, Dush, Niranjan, Nithya, D'Amours, Scott, Ashtari, Morvarid, Franco, Helena, Karim, Sabbir, Aman, Nowrin F., Estee, Mahnuma Mahfuz, Salma, Umme, Razzaque, Joyeta, Kanta, Tasnia Hamid, Tori, Sayeeda Aktar, Alamin, Shadid, Roy, Swapnil, Al Amin, Shadid, Karim, Rezaul, Haque, Muhtarima, Faruq, Amreen, Iftekhar, Farhana, O'Shea, Margaret, Padmore, Greg, Jonnalagadda, Ramesh, Litvin, Andrey, Filatau, Aliaksandr, Paulouski, Dzmitry, Shubianok, Maryna, Shachykava, Tatsiana, Khokha, Dziani, Khokha, Vladimir, Djivoh, Fernande, Dossou, Franci, Seto, Djifid Morel, Gbessi, Dansou Gaspard, Noukpozounkou, Bruno, Keke, Kpèmahouton René, Hodonou, Fred, Ahounou, Ernest Yemalin Stephane, Alihonou, Thierry, Dénakpo, Max, Ahlonsou, Germain, Bedada, Alemayehu Ginbo, Nsengiyumva, Carlo, Kwizera, Sandrine, Barendegere, Venerand, Choi, Philip, Jamal, Luai, Chen, Tzu‐Ling, Yip, Chingwan, Zapata, Felipe, Lanau, Maria Isabel Villega, Restrepo, Ivan Mendoza, Giraldo, Ruben Santiago Restrepo, Youssef, Mohamed, Thabet, Waleed, Sanad, Aly, Zaki, Ahmed, Abdel‐Hameed, Noran, Mostafa, Mohamed, Omar, Muhammad Fathi Waleed, Ghanem, Ahmed, Denewar, Adel, Emara, Eman, Rashad, Eman, Sakr, Ahmad, Elashry, Rehab, Emile, Sameh, Khafagy, Toqa, Elhamouly, Sara, Elfarargy, Arwa, Mohamed, Amna Mamdouh, Nagy, Ghada Saied, Esam, Abeer, Elwy, Eman, Hammad, Aya, Khallaf, Salwa, Ibrahim, Eman, Saidbadr, Ahmed, Moustafa, Ahmed, Mohammed, Amany Eldosouky, Elgheriany, Mohammed, Abdelmageed, Eman, Al Raouf, Eman Abd, Elbanby, Esraa Samir, Elmasry, Maha, Farahat, Mahitab Morsy, Mansor, Eman Yahya, Hegazy, Eman Magdy, Gamal, Esraa, Gamal, Heba, Kandil, Hend, Abdelrouf, Doaa Maher, Moaty, Mohamed, Gamal, Dina, El‐Sagheer, Nada, Salah, Mohamed, Magdy, Salma, Salah, Asmaa, Essam, Ahmed, Ali, Ahmed, Badawy, Mahmoud, Ahmed, Sara, Mohamed, Mazed, Assal, Abdelrahman, Sleem, Mohamed, Ebidy, Mai, Elrazek, Aly Abd, Zahran, Diaaaldin, Adam, Nourhan, Nazir, Mohamed, Hassanein, Adel B, Ismail, Ahmed, Elsawy, Amira, Mamdouh, Rana, Mabrouk, Mohamed, Ahmed, Lopna Ahmed Mohamed, Alnaby, Mohamed Hassab, Magdy, Eman, Abd‐Elmawla, Manar, Fahim, Marwan, Mowafy, Bassant, Mahmoud, Moustafa Ibrahim, Allam, Meran, Alkelani, Muhammad, El Gendy, Noran Halim, Aboul‐Naga, Mariam Saad, El‐Din, Reham Alaa, Elgendy, Alyaa Halim, Ismail, Mohamed, Shalaby, Mahmoud, Elsharkawy, Aya Adel, Moghazy, Mahmoud Elsayed, Elbisomy, Khaled Hesham, Shakshouk, Hend Adel Gawad, Hamed, Mohamed Fouad, Ebidy, Mai Mohamed, Ahmed, Hayam, Adel, Israa, Omar, Mohammad Elsayed, Ibrahim, Mohamed, Ghoneim, Omar, Hesham, Omar, Gamal, Shimaa, Hilal, Karim, Arafa, Omar, Awad, Sawsan Adel, Salem, Menatalla, Elsherif, Fawzia Abdellatif, Elsabbagh, Nourhan, Aboelsoud, Moustafa R., Rida, Ahmed Hossam Eldin Fouad, Hossameldin, Amr, Hany, Ethar, Asar, Yomna Hosny, Anwar, Nourhan, Gadelkarim, Mohamed, Abdelhady, Samar, Morshedy, Eman Mohamed, Saad, Reham, Soliman, Nourhan, Salama, Mahmoud, Ezzat, Eslam, Mohamed, Arwa, Ibrahim, Arwa, Fergany, Alaa, Mohammed, Sara, Reda, Aya, Allam, Yomna, Saad, Hanan Adel, Abdelfatah, Afnan, Fathy, Aya Mohamed, El‐Sehily, Ahmed, Kasem, Esraa Abdalmageed, Hassan, Ahmed Tarek Abdelbaset, Mohammed, Ahmed Rabeih, Saad, Abdalla Gamal, Ibrahim, Arij, Hassaan, Amr, Mohammed, Mohammed Mustafa, Elhoseny, Ghada, Magdy, Mohamed, Elkhalek, Esraa Abd, Zakaria, Yehia, Ezzat, Tarek, El Dahab, Ali Abo, Kelany, Mohamed, Arafa, Sara, Hassan, Osama Mokhtar Mohamed, Badwi, Nermin Mohamed, Sleem, Ahmad Saber, Ahmed, Hussien, Abdelbadeai, Kholoud, Abdullah, Mohamed Abozed, Lokman, Muhammad Amsyar Auni, Bahar, Suraya, Abdelazeam, Anan Rady, Adelshone, Abdelrahman, Hasnan, Muhammad Bin, Zulkifli, Athirah, Kamarulzamil, Siti Nur Alia, Elhendawy, Abdelaziz, Latif, Aliang, Adnan, Ahmad Bin, Shaharuddin, Shahadatul, Majid, Aminah Hanum Haji Abdul, Al‐Marakby, Dina, Ismail, Mohamad Jeffrey Bin, Basir, Elissa Rifhan Mohd, Ali, Citra Dewi Mohd, Ata, Aya Yehia, Nasr, Maha, Rezq, Asmaa, Sheta, Ahmed, Tariq, Sherif, Sallam, Abd Elkhalek, Darwish, Abdelrhman KZ, Elmihy, Sohaila, Elhadry, Shady, Farag, Ahmed, Hajeh, Haidar, Abdelaal, Abdelaziz, Aglan, Amro, Zohair, Ahmed, Essam, Mahitab, Moussa, Omar, El‐Gizawy, Esraa, Samy, Mostafa, Ali, Safia, Elhalawany, Esraa, Ata, Ahmed, El Halawany, Mohamed, Nashat, Mohamed, Soliman, Samar, Elazab, Alaa, Samy, Mostada, Abdelaziz, Mohamed A, Ibrahim, Khaled, Ibrahim, Ahmed mohamed, Gado, Ammar, Eldeen, Esraa Alm, loaloa, Mohamed Reda, Abouzaid, Arwa, Eldin, Mostafa Ahmed Bahaa, Hashad, Eman, Sroor, Fathy, Gamil, Doaa, Abdulhakeem, Eman Mahmoud, Zakaria, Mahmoud, Mohamed, Fawzy, Abubakr, Marwan, Ali, Elsayed, Magdy, Hesham, Ramadan, Menna Tallah, Mohamed, Mohamed Abdelaty, Mansour, Salma, Amin, Hager Abdul Aziz, Mohamed, Ahmed Rabie, Saami, Mahmoud, Elsayed, Nada Ahmed Reda, Tarek, Adham, Mahmoud, Sabry Mohy Eldeen, El Sayed, Islam Magdy, Reda, Amira, Shawky, Martina Yusuf, Salem, Mohammed Mousa, El‐Din, Shahinaz Alaa, Soliman, Noha Abdullah, Talaat, Muhammed, Alaael‐Dein, Shahinaz, Elhusseiny, Ahmed Abd Elmoen, Abdullah, Noha, Elshaar, Mohammed, Ibraheem, Aya AbdelFatah, Abdulaziz, Hager, Ismail, Mohammed Kamal, Madkor, Mona Hamdy, Abdelaty, Mohamed, Abdel‐Kader, Sara Mahmoud, Salah, Osama Mohamed, Eldafrawy, Mahmoud, Eldeeb, Ahmed Zaki, Eid, Mostafa Mahmoud, Attia, Attia, Shwky, Ayman, Badenjki, Mohamed Adel, Soliman, Abdelrahman, Al Attar, Samaa Mahmoud, Sayed, Farrag, Sabour, Fahd Abdel, Azizeldine, Mohammed G., Shawqi, Muhammad, Hashim, Abdullah, Aamer, Ahmed, Abdelraouf, Ahmed Mahmoud, Abdelshakour, Mahmoud, Ibrahim, Amal, Mahmoud, Basma, Mahmoud, Mohamed Ali, Qenawy, Mostafa, Rashed, Ahmed M., Dahy, Ahmed, Sayed, Marwa, Shamsedine, Ahmed W., Mohamed, Bakeer, Hasan, Ahmad, Saad, Mahmoud M., Bassit, Khalil Abdul, El‐Latif, Nadia Khalid Abd, Elzahed, Nada, El Kashash, Ahmed, Bekhet, Nada Mohamed, Hafez, Sarah, Gad, Ahmed, Maher, Mahmoud Elkhadragy, Elsameea, Ahmed Abd, Hafez, Mohamed, Sabe, Ahmad, Ahmed, Ataa, Shahine, Ahmed, Dawood, Khaled, Gaafar, Shireen, Husseiny, Reem, Aboelmagd, Omnia, Soliman, Ahmed, Mesbah, Nourhan, Emadeldin, Hossam, Al Meligy, Amgad, Bekhet, Amira Hassan, Hasan, Doaa, Alhady, Khaled, Sabe, Ahmad Khaled, Elnajjar, Mahmoud A., Aboelella, Majed, Hamsho, Ward, Hassan, Ihab, Saad, Hala, Abdelazim, Galaleldin, Mahmoud, Hend, Wael, Noha, Kandil, Ahmedali M, Magdy, Ahmed, Elkholy, Shimaa Said, Adel, Badr Eldin, Dabbour, Kareem, Elsherbiney, Saged, Mattar, Omar, Abdrabou, Abdulshafi Khaled, Aly, Mohammed Yahia Mohamed, Geuoshy, Abdelrahman, Elnagar, Ahmedglal, Ahmed, Saraibrahim, Abdelmotaleb, Ibrahem, Saleh, Amr Ahmed, Saeed, Manar, Mahmoud, Shady, Tawfik, Badreldin Adel, Ismail, Samar Adel, Zakaria, Esraay, Gad, Mariam O., Elhelbawy, Mohamed Salah, Bassem, Monica, Maraie, Noha, Elhadary, Nourhan Medhat, Semeda, Nourhan, Mohamed, Shaza Rabie, Bakry, Hesham Mohammed, Essam, AA, Tarek, Dina, Ashour, Khlood, Elhadad, Alaa, Abdel‐Aty, Abdulrahman, Rakha, Ibrahim, Matter, Sara Mamdouh, Abdelhamed, Rasha, Abdelkader, Omar, Hassaan, Ayat, Soliman, Yasmin, Mohamed, Amna, Farouk, Sara Amr Mohamed, Ibrahim, Eman Mohamed, El‐Taher, Esraa, Mostafa, Merna, Badr, Mohamed Fawzy Mahrou, Elsemelawy, Rofida, El‐Sawy, Aya, Bakr, Ahmad, Al Rafati, Ahmad Abdel Razaq, Saar, Sten, Reinsoo, Arvo, Seyoum, Nebyou, Worku, Tewodro, Fitsum, Agazi, Tolonen, Matti, Parmentier, Benoît, Dardenne, Sabrina, Robert, Elsa, Maillot, Betty, Courboin, Etienne, Hascoet, Juliette, Kaci, Amir Ait, Prudhomme, Thoma, Ballouhey, Quentin, Grosos, Céline, Fourcade, Laurent, Cecilia, Tolg, Jean‐Francois, Colombani, Helene, Francois‐Coridon, Delforge, Xavier, Haraux, Elodie, Dousset, Bertrand, Schiavone, Roberto, Gaujoux, Sebastien, Marret, Jean‐Baptiste, Haffreingue, Aurore, Rod, Julien, Renaux‐Petel, Mariette, Lecompte, Jean‐Françoi, Bréaud, Jean, Gastaldi, Pauline, Taieb, Chouikh, Claire, Raquillet, Anis, Echaieb, Bustangi, Nasir, Lopez, Manuel, Grella, Maria Giovanna, Mariani, Aurora, Schmitt, Françoise, Broch, Aline, Bandoh, Dickson, Kyereh, Martin, Asumah, Hamza, Appiah, Eric Kofi, Wondoh, Paul, Gyedu, Adam, Dally, Charle, Agbedinu, Kwabena, Amoah, Michael, Yifieyeh, Abiboye, Amoako‐Boateng, Mabel, Dayie, Makafui, Hagan, Richmond, Debrah, Sam, Ohene‐Yeboah, Micheal, Clegg‐Lampety, Joe‐Nat, Etwire, Victor, Dakubo, Jonathan, Essoun, Samuel, Bonney, William, Glover‐Addy, Hope, Osei‐Nketiah, Samuel, Amoako, Joachim, Adu‐Aryee, Niiarmah, Appeadu‐Mensah, William, Bediako‐Bowan, Antoinette, Dedey, Florence, Ekow, Mattew, Akatibo, Emmanuel, Yakubu, Musah, Kordorwu, Hope Edem Kofi, Asare‐Bediako, Kwasi, Tackie, Enoch, Aaniana, Kenneth, Acquah, Emmanuel, Opoku‐Agyeman, Richard, Avoka, Anthony, Kusi, Kwasi, Maison, Kwame, Gyamfi, Frank Enoch, Barnabas, Gandau Naa, Abdul‐Latif, Saiba, Amoako, Philip Taah, Davor, Anthony, Dassah, Victor, Dagoe, Enoch, Kwakyeafriyie, Prince, Akoto, Elliot, Ackom, Eric, Mensah, Ekow, Atkins, Ebenezer Takyi, Coompson, Christian Lari, Ivros, Nikolao, Ferousis, Christoforo, Kalles, Vasileio, Kyriazanos, Ioanni, Barkolias, Christo, Tselos, Angelo, Tzikos, Georgio, Voulgaris, Evangelo, Bamicha, Athanasia, Stefanopoulos, Anastasio, Patoulias, Ioanni, Sfougaris, Dimitrio, Valioulis, Ioanni, Balalis, Dimitrio, Korkolis, Dimitrio, Manatakis, Dimitrios K, Kyrou, Georgio, Karabelias, Georgio, Papaskarlatos, Iason‐Antonio, Konstantina, Kolonia, Zampitis, Nikolao, Papailia, Aspasia, Theodosopoulos, Theodosio, Gkiokas, Georgio, Mitroudi, Magdalini, Panteli, Christina, Feidantsis, Thoma, Farmakis, Konstantino, Kyziridis, Dimitrio, Ioannidis, Oresti, Parpoudi, Styliani, Parasyris, Stavro, Margaritis, Michail, Aguilera‐Arevalo, Maria‐Lorena, Coyoy‐Gaitan, Otto, Rosales, Javier, Tale, Lui, Rodriguez, Servio Tulio Torre, Galvez, Carlos Paz, Cruz, Danilo Herrera, Rosenberg, Guillermo Sanchez, Matheu, Alejandro, Cohen, David Monterroso, Paul, Marie, Charles, Angeline, Lam, Justin Chak Yiu, Yeung, Man Hon Andrew, Fok, Chi Ying Jacquelyn, Li, Ka Hin Gabriel, Lai, Anthony Chuk‐Him, Cheung, Yuk Hong Eric, Wong, Hong Yee, Leung, Ka Wai, Lee, Tien Seng Bryan, Lam, Wai Him, Dao, Weihei, Kwok, Stephanie Hiu‐wai, Chan, Tsz‐Yan Katie, Ng, Yung Kok, Mak, TWC, Foo, Chi Chung, Yang, Jame, Bhatnagar, Ankur, Upadhyaya, Vijaid, Muddebihal, Uday, Dar, Wasim, Janardha, KC, Aruldas, Neerav, Adella, Fidelis Jacklyn, Rulie, Anthonius Santoso, Iskandar, Ferdy, Setiawan, Jonny, Evajelista, Cicilia Viany, Natalie, Hani, Suyadi, Arlindawati, Gunawan, Rudy, Karismaningtyas, Herlin, Mata, Lusi Padma Sulistianingsih, Andika, Ferry Fitriya Ayu, Hasanah, Afifatun, Widiastini, T Ariani, Purwaningsih, Nurlaila Ayu, Mukin, Annisa Dewi Fitriana, Rahmah, Dina Faizatur, Nurqistan, Hazmi Dwinanda, Arsyad, Hasbi Maulana, Adhitama, Novia, Jeo, Wifanto Saditya, Sutandi, Nathania, Clarissa, Audrey, Gultom, Phebe Anggita, Billy, Matthew, Haloho, Andrea, Johanna, Nadya, Lee, Felix, Dorani, Radin Mohd Nurrahman Radin, Glynn, Martha, Alherz, Mohammad, Goh, Wennweoi, Shiwani, Haaris A., Sproule, Lorraine, Conlon, Kevin C., Bala, Miklosh, Kedar, Asaf, Bianco, Federica, Steccanella, Francesca, Gallo, Gaetano, Trompetto, Mario, Clerico, Giuseppe, Papandrea, Matteo, Sammarco, Giuseppe, Sacco, Rosario, Giavarini, Luisa, Giglio, Mariano Cesare, Bucci, Luigi, Pagano, Gianluca, Sollazzo, Viviana, Peltrini, Roberto, Luglio, Gaetano, Birindelli, Arianna, Mingrone, Pietro, Selvaggi, Francesco, Selvaggi, Lucio, Pellino, Gianluca, Di Martino, Natale, Curletti, Gianluca, Aonzo, Paolo, Galleano, Raffaele, Berti, Stefano, Francone, Elisa, Boni, Silvia, Lorenzon, Laura, lo Conte, Annalisa, Balducci, Genoveffa, Confalonieri, Gianmaria, Pesenti, Giovanni, Gavagna, Laura, Vasquez, Giorgio, Targa, Simone, Occhionorelli, Savino, Andreotti, Dario, Armellini, Andrea, Chiesa, Deborah, Aquilino, Fabrizio, Chetta, Nicola, Picciariello, Arcangelo, Abdelkhalek, Mohamed, Belli, Andrea, De Franciscis, Silvia, Bigaran, Annamaria, Favero, Alessandro, Basso, Stefano M.M, Salusso, Paola, Perino, Martina, Mochet, Sylvie, Sasia, Diego, Riente, Francesco, Migliore, Marco, Basilicò, Silvia, Corbellini, Carlo, Lazzari, Veronica, Angelieri, Daniele, Coletta, Diego, Falaschi, Federica, Catani, Marco, Reali, Claudia, Malavenda, Mariastella, Del Basso, Celeste, Ribaldi, Sergio, Coletti, Massimo, Natili, Andrea, Depalma, Norma, Iannone, Immacolata, Antoniozzi, Angelo, Rossi, Davide, Gui, Daniele, Perrotta, Gerardo, Ripa, Matteo, Giardino, Francesco Ruben, Foco, Maurizio, Vicario, Erika, Nita, Gabriela Elisa, Leone, Nicoletta, Simioni, Andrea, De Boni, Davide, Pasquali, Sandro, Goldin, Elena, Vendramin, Elena, Ciccioli, Eleonora, Tedeschi, Umberto, Violi, Paola, Campagnaro, Tommaso, Conci, Simone, Lazzari, Giovanni, Iacono, Calogero, Gulielmi, Alfredo, Manfreda, Serena, Rinaldi, Anna, Ringressi, Maria Novella, Brunoni, Beatrice, Salamone, Giuseppe, Mangiapane, Mirko, De Marco, Paolino, La Brocca, Antonella, Tutino, Roberta, Silvestri, Vania, Licari, Leo, Fontana, Tommaso, Falco, Nicolò, Cocorullo, Gianfranco, Shalaby, Mostafa, Sileri, Pierpaolo, Arcudi, Claudio, Bsisu, Isam, Aljboor, Khaled, Abusalem, Lana, Alnusairat, Aseel, Qaissieh, Ahmad, Al‐Dakka, Emad, Ababneh, Ali, Halhouli, Oday, Yusufali, Taha, Mohammed, Hussein, Lando, Justu, Parker, Robert, Ndegwa, Wairimu, Gribauskaite, Jolanta, Kuliavas, Justa, Dulskas, Audriu, Samalavicius, Narimantas E., Jasaitis, Kristijona, Parseliunas, Audriu, Nevieraite, Viktorija, Slapelyte, Evelina, Dainius, Edvina, Subocius, Andreju, Venclauskas, Lina, Gulbinas, Antana, Kasputyte, Simona, Mikuckyte, Deimante, Kiudelis, Mindauga, Jankus, Toma, Petrikenas, Stepona, Pažuskis, Mata, Urniežius, Zigmanta, Vilčinskas, Manta, Banaitis, Vincas Jona, Gaižauskas, Vytauta, Grisin, Edvard, Mazrimas, Povila, Drungilas, Manta, Lagunavicius, Karoli, Lipnickas, Vytauta, Majauskyté, Dovilè, Abaliksta, Toma, Uščinas, Laimona, Simutis, Gintara, Ladukas, Adoma, Danys, Donata, Sruogiene, Elena Zdanyte, Višinskas, Petra, Žilinskienė, Reda, Dragatas, Deivida, Burmistrovas, Andriu, Tverskis, Zygimanta, Vaicius, Artura, Mazelyte, Ruta, Zadoroznas, Antana, Žiubrytė, Greta, Rahantasoa, Finaritra Casimir Fleur Prudence, Samison, Luc Hervé, Rasoaherinomenjanahary, Fanjandrainy, Tolotra, Todisoa Emmanuella Christina, Mukuzunga, Corneliu, Kwatiwani, Chimwemwe, Msiska, Nelson, Chai, Feng Yih, Asilah, Siti Mohd Desa, Syibrah, Khuzaimah Zahid, Chin, Pui Xin, Riswan, Nur Zulaika, Chong, Hoong‐Yin, Aziz, Nora Abdul, Poh, Keat‐Seong, Chai, Chu‐Ann, Kumar, Sandip, Taher, Mustafa Mohammed, Aziz, Dayang Nita Abdul, Julaihi, Rokayah, Jethwani, Durvesh Lacthman, Yahaya, Muhammad Taqiyuddin, Mathew, Susan Wndy, Chung, Kuet Jun, Nirumal, Milaksh Kumar, Tze, R. 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Y., Koay, Kean Leong, Tan, Yi Koon, Cheah, Alvin Ee Zhiun, Wong, Chui Yee, Nur'Azmah Tuan Mat, Tuan, Chow, Crystal Yern Nee, Har, Prisca A.L., Der, Yishan, Henry, Fitjerald, Low, Xinwei, Neo, Ya Theng, Heng, Hian Ee, Kong, Shu Ning, Gan, Cheewei, Mok, Yi Ting, Tan, Yee Wen, Palayan, Kandasami, Tata, Mahadevan Deva, Cheong, Yih Jeng, Gunaseelan, Kuhaendran, 'Ain Wan Mohd Nasir, Wan Nurul, Yoganathan, Pigeneswaren, Lee, Eu Xian, Saw, Jian Er, Yeang, Li Jing, Koh, Pei Ying, Lim, Shyang Yee, Teo, Shuang Yi, Grech, Nicole, Magri, Daniela, Cassar, Kristina, Mizzi, Christine, Falzon, Malcolm, Shaikh, Nihaal, Scicluna, Ruth, Zammit, Stefan, Mizzi, Sean, Brincat, Svetlana Dori, Tembo, Thelma, Le, Vu Thanh Hien, Grima, Tara, Sammut, Keith, Carabott, Kurt, Zarb, Ciskje, Navarro, Andre, Dimech, Thea, Camilleri, Georgette Marie, Bertuello, Isaac, Dalli, Jeffrey, Bonavia, Karl, Corro‐Diaz, Samantha, Manriquez‐Reyes, Marisol, Abdelhamid, Amina, Hrora, Abdelmalek, Benammi, Sarah, Bachri, Houda, Abbouch, Meryem, Boukhal, Khaoula, Bennai, Redouane Mammar, Belkouchi, Abdelkader, Jabal, Mohamed Sobhi, Benyaiche, Chaymae, Vermaas, Maarten, Duinhouwer, Lucia, Pastora, Javier, Wood, Greta, Merlo, Maria Soledad, Ajao, Akinlabi, Ayandipo, Omobolaji, Lawal, Taiwo, Abdurrazzaaq, Abdussemiu, Alada, Muslimat, Nasir, Abdulrasheed, Habeeb, Olufemi, Mendel, Henry, Bello, Bashir, Muktar, Umar, Olajide, Thomas Olagboyega, Oshati, Oyindamola, Ihediwa, George, Adenekan, Babajide, Nwinee, Victor, Lawal, Abdulrazzaq, Bode, Chri, Olugbemi, Mojolaoluwa, Odutola, Oluwatomi, Adebola, Oluwaseyi, Onuoha, Clement, Balogun, Fatai, Ajai, Olalekan, Njokanma, Iloba, Kache, Stephen, Ajah, Jonathan, Makama, Jerry, Adamu, Ahmed, Baba, Suleiman, Aliyu, Mohammad, Aliyu, Shamsudeen, Ukwenya, Yahaya, Aliyu, Halima, Sholadoye, Tunde, Daniyan, Muhammad, Ogunsua, Oluseyi, Sheshe, Abdurrahaman, Mshelbwala, Philip, Samson, Garba, Timothy, Oyediran Kehinde, Samuel, Sani Ali, Ajiboye, Anthony, Amole, Isaac, Abiola, Olajide, Olaolorun, Akin, Veen, Torhild, Kanani, Arezo, Styles, Kristian, Herikstad, Ragnar, Larsen, Johannes Wiik, Søreide, Jon Arne, Jensen, Elisabeth, Gran, Mad, Aahlin, Eirik Kju, Gaarder, Tina, Monrad‐Hansen, Peter Wiel, Næss, Pål Aksel, Lauzikas, Giedriu, Wiborg, Joachim, Holte, Silje, Augestad, Knut Magne, Banipal, Gurpreet Singh, Moe, Thomas Teten, Schultz, Johannes Kurt, Al‐taher, Taher, Hamdan, Ayah, Salman, Ayman, Saadeh, Rana, Musleh, Aseel, Jaradat, Dana, Abushamleh, Soha, Hanoun, Sakhaa, Qumbos, Amjad Abu, Hamarshi, Aseel, Taher, Ayman And, Qawasmi, Israa, Qurie, Khalid, Altarayra, Marwa, Ghannam, Mohammad, Shaheen, Alaa, Herebat, Azher, Abdelhaq, Aram, Shalabi, Ahmad, Abu‐toyour, Maram, Asi, Fatema, Shamasneh, Ala, Atiyeh, Anwar, Mustafa, Mousa, Zaa'treh, Rula, Dabboor, Majd, Alaloul, Ena, Baraka, Heba, Meqbil, Jehad, Al‐Buhaisi, Alaa, Elshami, Mohamedraed, Afana, Samah, Jaber, Sahar, Alyacoubi, Said, Abuowda, Yousef, Idress, Tasneem, Abuqwaider, Eman, Al‐saqqa, Sara, Bowabsak, Alaa, El Jamassi, Alaa, Hasanain, Doaa, Al‐farram, Hadeel, Salah, Maram, Firwana, Aya, Hamdan, Marwa, Awad, Israa, Ashour, Ahmad, Al Barrawi, Fayez Elian, Al‐khatib, Ahmed, Al‐faqawi, Maha, Fares, Mohamed, Elmashala, Amjad, Adawi, Mohammad, Adawi, Ihdaa, Khreishi, Reem, Khreishi, Rose, ashour, Ahmad, Ghaben, Ahed, Nadeem, Najwa, Saqlain, Muhammad, Abbasy, Jibran, Alvi, Abdul Rehman, Shahzad, Noman, Butt, Muhammad Talha, Asaat ul Razi, Syed, Ahmed, Asdaq, Niazi, Ali Khan, Raza, Ibrahim, Baluch, Fatima, Raza, Ahmed, Bani‐Sadar, Ahmad, Adil, Muhammad, Raza, Awai, Javaid, Mahnoor, Waqar, Muhammad, Khan, Maryam Ali, Arshad, Mohammad Mohsin, Amjad, Mohammadasim, Cardozo, Jorge Torre, Roche, Marcelo O'Higgin, Servin, Gustavo Rodolfo Pertersen, Lopez, Larissa Ines Páez, Cardozo, Ramón Augusto Melo, Espinoza, Fernando, Rojas, Angel David Pérez, Sanchez, Diana, Samaniego, Camila Sanchez, Torres, Shalon Guevara, Calua, Alexander Canta, Razuri, Cesar, Ortiz, Nadia, Rodriguez, Xianelle, Carrasco, Nahilia, Saravia, Fridiz, Miyasato, Hector Shibao, Valcarcel‐Saldaña, María, Bermúdez, Ysabel Esthefany Alejo, Carpio, Juan, Panez, Walter Ruiz, Orbegozo, Pedro Angel Toribio, Dueñas, Carolina Guzmán, Espinoza, Kevin Turpo, Barrantes, Ana Maria Sandoval, Bravo, Jorge Armando Chungui, Fuentes‐Rivera, Lorena, Fernández, Carmen, Málaga, Bárbara, Ye, Joselyn, Velasquez, Ricardo, Salcedo, Jannin, Contreras‐Vergara, Ana Lucia, Mejia, Angelica Genoveva Vergara, Montejo, Maria Soledad Gonzale, Salas, Marilia Del Carmen Escalante, Ticona, Willy Alcca, Vargas, Marvin, Sila, George Christian Manrique, Mas, Robinson, Pilar Paucar, Arazzelly, Velásquez, Armando José Román, Robledo‐Rabanal, Alina, Solis, Ludwing Alexander Zeta, Espinoza, Kenny Turpo, Hamaguchi, José Luis Hamasaki, Farfan, Erick Samuel Florez, Barrientos, Linda Alvi Madrid, Matta, Juan Jaime Herrera, Mora, John Jemuel V., Redota, Menold Archee P., Roxas, Manuel Francisco, Maño, Maria Jesusa B., Parreno‐Sacdalan, Marie Dione, Almanon, Christel Leanne, Walędziak, Maciej, Roszkowski, Rafał, Janik, Michał, Lasek, Anna, Radkowiak, Dorota, Rubinkiewicz, Mateusz, Fernandes, Cristina, Muntean, Liviu, Popa, Mariuca, Mircea, Hogea, Diaconescu, Bogdan, Bratu, Matei Razvan, Negoi, Ionut, Ciubotaru, Cezar, Uzabumwana, Norbert, Duhoranenayo, Dieudonne, Idris, Faisal, Alghamdi, Mohammed Saleh A., Maghrabi, Ashraf, Alkaaki, Aroub, Turkustani, Sondo, Khalifah, Eyad, Albiety, Adel, Sahel, Sarah, Alshareef, Reham, Alzahrani, Mohammed Najjar Ahmed, Alghamdi, Ahmed, Alhazmi, Wedyan, Al Saied, Ghiath, Alamoudi, Mohammed, Riaz, Muhammed Masood, Alhassan, Basmah, Altamimi, Abdullah, Alyahya, Reem, Al Subaie, Norah, Al Bastawis, Fatema, Khan, Roaa, Radojkovic, Milan, Jeremic, Ljiljana, Nestorovic, Milica, Law, Jia Hao, Tan, Keith Say Kwang, Tan, Ryan Choon Kiat, Tan, Joel Kin, Joel, Lau Wen Liang, Chan, Xue Wei, Leong, Faith Qi Hui, Chong, Choon Seng, Koh, Sharon, Lee, Kai Yin, Lee, Kuok Chung, Pluke, Kent, Dedekind, 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Ruth, Andriola, Valeria, Contreras, Elisa, Bernardo, Carmen García, Sanz, Sandra, León, Alberto Miyar, Dorismé, Asnel, Rodicio, Joselui, Suarez, Aida, Stuva, Jessica, Vico, Tamara Diaz, Fernandez‐Vega, Laura, Soldevila‐Verdeguer, Carla, Sena‐Ruiz, Fatima, Pujol‐Cano, Natalia, Diaz‐Jover, Paula, Garcia‐Perez, José Maria, Segura‐Sampedro, Juan Jose, Pineño‐Flores, Cristina, Ambrona‐Zafra, David, Craus‐Miguel, Andrea, Jimenez‐Morillas, Patricia, Mazzella, Angela, Jayathilake, A.B, Thalgaspitiya, S.P.B, Wijayarathna, L.S., Wimalge, P.M.S.N., Sanni, Hakeem Ayomi, Okenabirhie, Ogheneochuko, Homeida, Anmar, Younis, Abobaker, Omer, Omer Abdelbagi, Abdulaziz, Mustafa, Mussad, Ali, Adam, Ali, Sokratous, Aresti, Breistrand, Michaela, Sigurdadottir, Johanna, Nikberg, Maziar, Chabok, Abba, Elbe, Peter, Saraste, Deborah, Rutkowski, Wiktor, Forlin, Louise, Niska, Karoliina, Oswald, Denni, Peros, Georgio, Bluelle, Rafael, Reinisch, Katharina, Frey, Daniel, Palma, Adrian, Zumbühl, Luciu, Werder, Gabriela, Mahanty, Silke, Widmer, Lukas Werner, Müller, Julia, Gübeli, Alissa, Zuk, Grzegorz, Gulcicek, Osman Bilgin, Vartanoglu, Talar, Kose, Emin, Karahan, Servet Rustu, Aydin, Mehmet Can, Sahbaz, Nuri Alper, Halicioglu, Ilkay, Alis, Halil, Sapci, Ipek, Adıyaman, Can, Pektaş, Ahmet Murat, Cengiz, Turgut Bora, Tansoker, Ilkan, Işler, Vedatcan, Cevik, Muazzez, Mutlu, Deniz, Ozben, Volkan, Ozmen, Berk Bari, Bayram, Sefa, Yolcu, Sinem, Kobal, Berna Buse, Toto, Ömer Faruk, Çakaloğlu, Haluk Cem, Karabulut, Kagan, Mutlu, Vahit, Celik, Saban, Semiz, Anil, Bodur, Selim, Gül, Enisburak, Murutoglu, Busra, Yildirim, Reyyan, Baki, Bahadir Emre, Arslan, Ekin, Ulusahin, Mehmet, Guner, Ali, Walker, Nathan, Shrimanker, Nikhita, Cole, Simon, Breslin, Ryan, Srinivasan, Ravi, Hunter, Kristina, Al‐Bahrani, Ahmed, Mairs, Nora Grace, Rocke, Alistair, Dick, Lachlan, Qureshi, Mobeen, Chowdhury, Debkumar, Wright, Naomi, Skerritt, Clare, Kufeji, Dorothy, Ho, Adrienne, Dissanayake, Tharindra, Tennakoon, Athula, Ali, Wadah, Tan, Charlene, O'Neill, Stephen, Knight, Stephen, Nassif, Dima, Sharma, Abhishek, White, Rebecca, Mehdi, Aia, Post, Nathan, Kalakouti, Eliana, Dashnyam, Enkhbat, Stourton, Frederick, Mykoniatis, Ioanni, Wong, Francisca, Gupta, Ashish, Shatkar, Veeranna, Kadiwar, Suraj, Smedley, Alexander, Wakefield, Rebecca, Herrod, Philip, Blackwell, Jame, Cohen, Fraser, Bandi, Ashwath, Bond‐Smith, Gile, Farhangmehr, Neda, Perenyei, Miklo, Ireland, Philip, Bowling, Kirk, Bunting, David, Longstaff, Lydia, Keogh, Kenneth, Jeon, Hyunjin, Iqbal, Muhammad Rafaih, Khosla, Shivun, Jeffery, Anna, Perera, Jame, Alhammali, Tariq, Oram, Shaun, Kidd, Thoma, Cullen, Fraser, Owen, Christopher, Wilson, Michael, Chiu, Seehui, Sarafilovic, Hannah, Ploski, Jennifer, Evans, Elizabeth, Abbas, Athar, Kamya, Sylvia, Ishak, Norzawani, Bisset, Carly, Andress, Cedar, Chin, Ye Ru, Patel, Priya, Evans, David, Haslegrave, Aidan, Boggon, Adam, Laurie, Kirsten, Mann, Thoma, Mansuri, Anahita, Davies, Rachel, Shahbaz, Aized Raza, Eng, Calvin, Din, Farhat, L'Heveder, Ariadne, Park, Esther H.G., Ravishankar, Ramanish, McIntosh, Kirsten, Yau, Jih Dar, Chan, Luke, McGarvie, Susan, Tang, Lingshan, Lim, Hui, Yap, Suhhuey, Park, Jay, Ng, Zhan Herr, Mirza, Shahrukh, Ang, Yun Lin, Walls, Luke, Roy, Chloe, Paterson‐Brown, Simon, Mclean, Kenneth, D'Souza, Michelle S, Pronin, Savva, Henshall, David Ewart, Ter, Eunice Zuling, English, William, Morgan, Catrin, Townsend, Dominic, Maciejec, Laura, Mahdi, Shareef, Akpenyi, Onyinye, Hall, Elisabeth, Caydiid, Hanaan, Rob, Zakaria, Abbott, Tom, Torrance, Hew D, Johnston, Robin, Gani, Mohammed Akil, Rajmohan, Shivanchan, Majid, Kiran, Smith, Christopher, Palliyil, Madanmohan, Patel, Sanjay, Nicholson, Luke, Harvey, Neil, Shillito, Sam, Kershaw, Suzanne, Bamford, Rebecca, Orton, Peter, Reunis, Elke, Jama, Guled M., Dhillon, Dharminder, Patel, Khyati, Nanthakumaran, Shayanthan, Heard, Rachel, Chen, Kar Yan, Barmayehvar, Behrad, Datta, Uttaran, Kamarajah, Sivesh K, Tani, Sobhana Iftekhar, Donnelly, Philippa, Walker, Michael, Blacker, Sarah, Kaul, Anil, Paramasivan, Arjun, Farag, Sameh, Nessa, Ashrafun, Awadallah, Salwa, Lim, Jieqi, Ng, James Chean Khun, Kiran, Ravi P., Murray, Alice, Dasari, Mohini, Puyana, Juan, Haddad, Nadeem, Zielinski, Martin, Choudhry, Asad, Caliman, Celeste, Beamon, Mieshia, Duane, Therese, Myers, Jonathan, Deal, Rebecca, Makupe, Alex, Musowoya, Joseph, Van Der Naald, Niel, Kumwenda, Dayson, Reece‐Smith, Alex, Otten, Kar, Verbeek, Anna, Prins, Marloe, Suarez, Alibeth Andres Baquero, Deane, Chelsea, Dijan, Emilio, Elfiky, Mahmoud, Koskenvuo, Laura, Thollot, Aurore, Limoges, Bernard, Capito, Carmen, Alexandre, Challine, Kotobi, Henri, Leroux, Julien, Pinnagoda, Kalitha, Henric, Nicola, Azzis, Olivier, Rosello, Olivier, Francois, Poddevin, Etienne, Sara, Buisson, Philippe, Hmila, Sophian, Clegg‐Lamptey, Joe‐Nat, Imoro, Osman, Abem, Owusu Emmanuel, Papageorgiou, Dimitrio, Soulou, Vasiliki, Asturias, Sabrina, Peña, Lenin, O'Connor, Donal B, Luc, Alberto Reali, Russo, Alfio Alessandro, Ruzzenente, Andrea, Taddei, Antonio, Cona, Camilla, Bottini, Corrado, Pascale, Giovanni, Rotunno, Giuseppe, Solaini, Leonardo, Pascale, Marco Maria, Notarnicola, Margherita, Corbellino, Mario, Sacco, Michele, Ubiali, Paolo, Cautiero, Roberto, Bocchetti, Tommaso, Muzio, Elena, Guglielmo, Vania, Morandi, Eugenio, Mao, Patrizio, De Luca, Emilia, Ali, Farah Mahmoud, Žilinskas, Justa, Kondrotas, Pauliu, Baltrunas, Roberta, Kutkevicius, Juoza, Ignatavicius, Povila, Tan, Choy Ling, Siaw, Jia Yng, Yam, Sir Young, Wilson, Ling, Aziz, Mohamed Rezal Abdul, Bondin, John, Zorrilla, Carmina Diaz, Majbar, Ana, Sale, Danjuma, Abdullahi, Lawal, Osagie, Olabisi, Faboya, Omolara, Fatuga, Adedeji, Taiwo, Agboola, Nwabuoku, Emeka, Bliksøen, Marte, Khan, Zain Ali, Coronel, Jazmin, Miranda, Cesar, Vasquez, Idelso, Helguero‐Santin, Luis M., Rickard, Jennifer, Adedeji, Adesina, Alqahtani, Saleh, Rath, Max, Van Niekerk, Michael, Koto, Modise Zacharia, Matos‐Puig, Roel, Israelsson, Leif, Schuetz, Tobia, Yuksek, Mahmut Arif, Mericliler, Meric, Uluşahin, Mehmet, Yong, Guo Liang, Whitehurst, Katharine, Redgrave, Natalie, Musyoka, Caroluce K, Olivier, Jame, Lee, Kathryn, Cox, Michael, Farhan‐Alanie, Muhamed M H, Callan, Rory, Chibuye, Chali, Ali, Tebian Hassanein Ahmed, Rekhis, Syrine, Rommaneh, Muna, Sam, Zi Hao, Chen, Jacky Hong Chieh, Roi, Dylan, Pugliesi, Thays Brunelli, Pardo, Gabriel, Blanco, Ruth, Escobar, Eugenio Grasset, GlobSurg Collaboration, Group, and Sileri, P
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Male ,modelos logísticos ,medicine.medical_treatment ,humanos ,surgial care ,Colorectal Neoplasm ,países desarrollados ,Logistic regression ,outcomes ,Global Health ,urgencias médicas ,0302 clinical medicine ,países en desarrollo ,Surgical ,estudios prospectivos ,Colostomy ,80 and over ,globalsurg ,030212 general & internal medicine ,Prospective Studies ,Prospective cohort study ,Multivariate Analysi ,mediana edad ,Cancer ,Aged, 80 and over ,Emergencie ,anciano ,Anastomosis, colorectal resection, colostomy ,Anastomosis, Surgical ,General Medicine ,Middle Aged ,adulto ,colostomy ,colorectal cancer ,human developlment index ,3. Good health ,Colo-Rectal Cancer ,traditional healers ,Elective Surgical Procedures ,030220 oncology & carcinogenesis ,Female ,Colorectal Neoplasms ,6.4 Surgery ,low income ,Cohort study ,Human ,Developed Countrie ,Adult ,Aged ,Emergencies ,Humans ,Logistic Models ,Multivariate Analysis ,Developed Countries ,Developing Countries ,medicine.medical_specialty ,neoplasias colorrectales ,Logistic Model ,cancer, anastomosis, surgical, income, stomas, colostomy procedure, colorectal resection, end colostomy, emergency surgical procedure, human development index ,delay ,Anastomosis ,Perforation (oil well) ,lcsh:Surgery ,GlobalSurg Collaborative ,NO ,03 medical and health sciences ,Case mix index ,Clinical Research ,medicine ,cancer ,análisis multifactorial ,emergency abdominal surgery, low income, surgial care, traditional healers, cancer, mortality, outcomes, delay ,Elective Surgical Procedure ,business.industry ,Kirurgi ,left colon resection, anastomosis, end colostomy ,Evaluation of treatments and therapeutic interventions ,lcsh:RD1-811 ,Odds ratio ,mortality ,Surgery ,Prospective Studie ,business ,Digestive Diseases ,colostomía ,emergency abdominal surgery - Abstract
Background: End colostomy rates following colorectal resection vary across institutions in high-income settings, being influenced by patient, disease, surgeon and system factors. This study aimed to assess global variation in end colostomy rates after left-sided colorectal resection. Methods: This study comprised an analysis of GlobalSurg-1 and -2 international, prospective, observational cohort studies (2014, 2016), including consecutive adult patients undergoing elective or emergency left-sided colorectal resection within discrete 2-week windows. Countries were grouped into high-, middle- and low-income tertiles according to the United Nations Human Development Index (HDI). Factors associated with colostomy formation versus primary anastomosis were explored using a multilevel, multivariable logistic regression model. Results: In total, 1635 patients from 242 hospitals in 57 countries undergoing left-sided colorectal resection were included: 113 (6.9 per cent) from low-HDI, 254 (15.5 per cent) from middle-HDI and 1268 (77.6 per cent) from high-HDI countries. There was a higher proportion of patients with perforated disease (57.5, 40.9 and 35.4 per cent; P, Medical Research Council, MR/N022114/1; National Institute for Health Research, 16/136/79
- Published
- 2019
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14. Ankle-Brachial Index and cardiovascular events in atrial fibrillation The ARAPACIS Study
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Violi, F., Davi, G., Proietti, M., Pastori, D., Hiatt, W. R., Corazza, G. R., Perticone, F., Pignatelli, P., Farcomeni, A., Vestri, A. R., Lip, G. Y. H., Basili, S, ARAPACIS (Atrial Fibrillation Registry for Ankle-Brachial Index Prevalence Assessment-Collaborative Italian Study) STUDY Investigators. Alessandri C. (Dipartimento di Scienze e Biotecnologie Medico-Chirurgiche, Sapienza-Università di Roma), Serviddio G. (Department of Medical and Surgical Sciences, University of Foggia), (UOC Medicina Generale, Fascetti S., USL 12 Viareggio, Toscana), (UOC Medicina Interna I, Palange P., Dipartimento di Sanità Pubblica, e Malattie Infettive, Sapienza-Università di Roma), Greco, E., (Medicina 3, Bruno G., Department of Medical Sciences, Città della Salute e della Scienza, A. O., University of Turin), Averna, M., (Dipartimento Biomedico di Medicina Interna e Specialistica, Giammanco A., Università di Palermo), Sposito P. (Azienda Ospedaliera Ospedali Riuniti Papardo Piemonte, Messina), De Cristofaro, R., (Istituto di Medicina Interna e Geriatria, De Gennaro L., Centro Emostasi, e Trombosi, Gemelli, Policlinico A., Roma), Carulli, L., (UO di Medicina a Indirizzo Nutrizionistico e Metabolico, Pellegrini E., Università degli Studi di Modena e Reggio Emilia), Dipartimento Integrato di Medicina Endocrinologia Metabolismo e Geriatria., Cominacini, L., Mozzini, C., (Dipartimento di Medicina, Pasini A. F., Sezione di Medicina Interna, D, Università di Verona), Sprovieri, M., (UOC Medicina d'Urgenza e PS, Spagnuolo V., Stabilimento Ospedaliero dell'Annunziata, Cosenza), (UOC Medicina Interna per l'Urgenza, Cerqua G., S Giovanni Addolorata, Ao, Cerasola G., Mulé G. (Università degli Studi di Palermo), Barbagallo, M., Lo Sciuto, S., (UOC di Geriatria e Lungodegenza, Monteverde A., Azienda Ospedaliera Universitaria Policlinico, Aoup, Palermo), Saitta, A., (UOC Medicina Interna, Lo Gullo A., Università di Messina), Malatino, L., Cilia, C., Terranova, V., (Clinica Medica, Pisano M., Ospedale, Cannizzaro, Università degli Studi di Catania), Pinto, A., Di Raimondo, D., Tuttolomondo, A., (Internal Medicine and Cardio-Angiology Ward, Conigliaro R., Department of Biomedicine and Internal Medicine, University of Palermo), Signorelli S. (Dipartimento di Medicina Interna e Patologia, Università degli Studi di Catania), De Palma, D., Galderisi, M., (Dipartimento di Medicina Clinica e Sperimentale, Cudemo G., AUP Federico II di Napoli), Galletti, F., (Dipartimento di Medicina Clinica e Chirurgia, Fazio V., Università di Napoli Federico II), De Luca, N., (Centro Ipertensione, Meccariello A., AUO Federico II, Napoli), Caputo, D., (UO Medicina Interna, De Donato M. T., Azienda Ospedaliera Universitaria San Giovanni di Dio, e Ruggi D'Aragona, Salerno), Iannuzi, A., (Divisione di Medicina Interna, Bresciani A., Cardarelli, Osp. A., (V Divisione Medicina Interna ed Immunoallergologia, Giunta R., Policlinico, Sun, Utili, R., (Medicina Infettivologica e dei Trapianti, Iorio V., Seconda Università di Napoli, AORN dei Colli-Monaldi), Adinolfi, L. E., Sellitto, A., (Medicina Interna, Iuliano N., Ospedale di Marcianise), Bellis, P., (UOC Medicina Interna e di Urgenza e Pronto Soccorso, Tirelli P., del Loreto Nuovo, P. O. S. M., Loreto, Mare), (Clinica Medica 5, Sacerdoti D., Dipartimento di Medicina DIMED, Università degli Studi di Padova), (UO Medicina Interna Arezzo, Vanni D., Ospedale San Donato, Azienda USL, 8 Arezzo), Iuliano, L., Ciacciarelli, M., (Department of Medico-Surgical Sciences and Biotechnology, Pacelli A., Vascular Biology, Mass Spectrometry Lab, Sapienza-University of Rome), Palazzuoli A. (UOS Malattie Cardiovascolari Dipartimento di Scienze Mediche Chirurgiche e Neuroscienze, Università di Siena), Cacciafesta, M., Gueli, N., Lo Iacono, C., Brusco, S., (UOC di Medicina Geriatrica e Riabilitazione, Verrusio W., Sapienza-Università di Roma, Nobili, L., Tarquinio, N., (UO Medicina 'SS Benvenuto e Rocco', Pellegrini F., Dipartimento di Medicina Interna, Asur, Marche, Area Vasta, n. 2., ex ZT 7), (UOS Breve Osservazione, Vincentelli G. M., Calibita 'Fatebenefratelli' Isola Tiberina, Ospedale S. G., Ravallese, F., (UOC Medicina Interna, Santini C., Ospedale, Vannini, Letizia, C., Petramala, L., (UOD Ipertensione Secondaria, Zinnamosca L., Dipartimento di Medicina Interna, e Specialità Mediche, Minisola, S., Cilli, M., Savoriti, C., (UOC Medicina Interna F e Malattie Metaboliche dell'osso- Sapienza-Università di Roma), Colangelo L., Falaschi, P., Martocchia, A., (UO Geriatria, Pastore F., Andrea, Azienda Ospedaliera S., Facoltà diMedicina, e Psicologia, Bertazzoni, G., (UOC Medicina d’Urgenza, Attalla El Halabieh E., Dipartimento di Emergenza ed Accettazione, Paradiso, M., Lizzi, E. M., (Ospedale San Giovanni Battista, Timmi S., Ordine di Malta, (Medicina Interna II, Battisti P., Ospedale San Giovanni-Addolorata, (UOC Medicina Interna, Cerci S., Ospedali Riuniti Frascati, Marino), (UOC Cardiologia-UTIC, Ciavolella M., Ospedale di Frascati, (Centro dell’Ipertensione Arteriosa e delle Malattie Metaboliche e Renali, Di Veroli C., Casa di Cura 'San Domenico', Malci, F., (UOC di Medicina Interna, De Ciocchis A., Ospedale, ASL Roma, G, Subiaco), Abate, D. (Az., Castellino, P., Zanoli, L., (UOC Medicina Interna, Fidone F., Dipartimento di Medicina Clinica, e Sperimentale, Mannarino, E., Pasqualini, L., (Medicina Interna, Oliverio G., Università degli Studi di Perugia), Pende, A., (Clinica di Medicina Interna 1, Artom N., Università di Genova, San Martino - IST), IRCCS Az. Osp. Univ., Ricchio, R., (UOC Geriatria, Fimognari F. L., Azienda Ospedaliera di Cosenza, Alletto, M., (Unità Operativa di Medicina, Messina S., Elia, Ospedale S., Caltanissetta), Sesti, G., Arturi, F., Fiorentino, T. V., (Università degli Studi, Pedace E., UOC Medicina Interna, Policlinico Universitario 'Mater Domini'), Scarpino, P. E., Carullo, G., Maio, R., (Cattedra di Medicina Interna, Sciacqua A., UO Malattie Cardiovascolari, Campus Universitario di Germaneto, Università Magna Graecia di Catanzaro), Frugiuele, P., (UOC Medicina Interna e Reumatologia, Spagnuolo V., Stabilimento Ospedaliero Annunziata, Azienda Ospedaliera Cosenza), (UO Lungodegenza, Battaglia G., Serra San Bruno, S. O., ASP Vibo Valentia), Atzori, S., (Clinica Medica, Delitala G., Aou, Sassari), Angelucci, E., (UOC di Clinica Medica, Sestili S., PO Clinicizzato di Chieti), Traisci, G., (UOC Medicina Interna 2, De Feudis L., PO di Pescara), Di Michele, D., (UOC Medicina Interna, Fava A., Asl, Teramo), Balsano, C., (Dipartimento di Medicina Interna e Sanità Pubblica, De Ciantis P., Università, dell'Aquila), Desideri, G., (UOC Geriatria e Lungodegenza Geriatrica, Camerota A., Dipartimento Medico ORM, Avezzano), Po, Mezzetti M. (UOC Medicina Interna Ospedale del Casentino-Direttore Dr. Emilio Santoro, AUSL8 Arezzo), Gresele, P., Vedovati, C., (Dipartimento di Medicina Interna, Fierro T., Sezione di Medicina Interna, e Cardiovascolare, Università di Perugia), (Centro Aterosclerosi, Puccetti L., Trombosi, e Coagulopatie, Università degli Studi di Siena, Azienda Ospedaliero-Universitaria Senese), Bertolotti, M., (UO Geriatria, Mussi C., Boddi, M., Savino, A., Contri, S., (Dipartimento di Medicina Sperimentale e Clinica, Degl'Innocenti G., Università degli Studi di Firenze), Saller, A., (Clinica Medica 1, Fabris F., Medicina Interna CLOPD, Departement of Medicine DIMED, University of Padova), Pesavento, R., Filippi, L., (Dipartimento di Scienze Cardiologiche, Vedovetto V., Toraciche, e Vascolari, Clinica Medica, 2, Azienda Ospedaliera-Università di Padova), (Clinica Medica IV, Puato M., Dipartimento di Medicina, Azienda Ospedaliera Universitaria Padova, Padova), Fabris, F., (UOA Medicina, Treleani M., Policlinico, Universitario, De Luca, E., De Zaiacomo, F., (Clinica Geriatrica, Giantin V., Università di Padova), (Medicina Interna 1, Semplicini A., Giovanni e Paolo, Ospedale SS., Venezia), Minuz, P., (Sezione di Medicina Interna C, Romano S., Università di Verona, Aoui, Verona), Fantin, F., (Dipartimento di Medicina, Manica A., Sezione di Geriatria, Stockner, I., Pattis, P., Wiedermann, Gutmann B. (Divisione di Medicina Interna-Direttore Prof. J., Ospedale Centrale di Bolzano), Catena, C., Colussi, G., (Clinica Medica, Sechi L. A., Dipartimento di Scienze Mediche Sperimentali, e Cliniche, Università di Udine, Italy), Annoni, G., Bruni, A. A., (Clinica Geriatrica, Castagna A., Università degli Studi di Milano-Bicocca, Dipartimento di Medicina, e Chirurgia, AO San Gerardo, Monza), (Medicina Interna 1, Spinelli D., Dipartimento di Scienze Cliniche, e di Comunità, Fondazione, Irccs, Università di Milano), (Clinica Medica I, Miceli E., Reparto, 11, IRCCS Policlinico San Matteo di Pavia), Schinco, G., (UOC Geriatria, Spreafico S., Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico), (UOC Medicina Interna, Secchi B., Ospedale, Bassini, Milano), Vanoli, M., Casella, G., (SC Medicina Interna, Pulixi E. A., Azienda Ospedaliera della Provincia di Lecco, Ospedale di Merate, Lecco), Sansone, L., (UOC Medicina, Serra M. G., Panico', Azienda Ospedaliera 'Cardinale G., Tricase, (Lecce), Longo, S., (UOC Medicina Interna, Antonaci S., Azienda Ospedaliera Policlinico, Bari), Belfiore, A., Frualdo, M., Palasciano, G., Murri'- Bari), Ricci L. (Clinica Medica 'A., (Struttura Complessa di Medicina Interna, Ventrella F., Cerignola, Asl, Foggia), (UOC Medicina Interna, Bianco C., Tropea), Santovito, D., (Centro di Eccellenza Europeo e di Riferimento Regionale per l'Aterosclerosi, Cipollone F., l'Ipertensione Arteriosa, e le Dislipidemie, Università, Chieti), Nicolai, S., (UO Medicina Interna, Salvati F., Ospedale di Ortona, ASL 02 Abruzzo), Rini, G. B., (UOC Medicina Interna ed Ipertensione, Scozzari F., Dipartimento Biomedico di Medicina Interna, e Specialistica, Giaccone' di Palermo), Policlinico 'P., Muiesan, M. L., Salvetti, M., (Dipartimento di Scienze Cliniche e Sperimentali, Bazza A., Università di Brescia, 2° Medicina Generale Spedali Civili), Picardi, A., Vespasiani-Gentilucci, U., (Medicina Interna e Epatologia, De Vincentis A., Università Campus Bio-Medico, Cosio, P., (Medicina Interna 1, Terzolo M., Dipartimento di Scienze Cliniche, e Biologiche, AOU San Luigi Gonzaga, Università di Torino), Madaffari, B., (UO Medicina Interna, Parasporo B., Azienda Ospedaliera Bianchi Melacrino Morelli, Reggio, Calabria), Fenoglio, L., Bracco, C., (SC Medicina Interna, Melchio R., Croce e Carle, AO S., Cuneo), Gentili, T., (Medicina Generale - Settore Subintensivo, Salvi A., Azienda Ospedaliero- Universitaria, Ancona), (Medicina Generale - Settore Ordinario, Nitti C., Azienda, Ospedaliero-Universitaria, Gabrielli, A., (Clinica Medica, Martino G. P., Capucci, A., Brambatti, M., (Clinica di Cardiologia, Sparagna A., Ospedale, Torrette, (UO Medicina Generale IV, Tirotta D., Ospedale, Cervesi, Cattolica), Andreozzi, P., Ettorre, E., Viscogliosi, G., Servello, A., (Area Geriatria, Musumeci M., DAI Medicina Interna, Rossi Fanelli, F., Delfino, M., (UOC Medicina Interna H, Giorgi A., Sapienza- Università di Roma), Glorioso, N., Melis, G., Marras, G., (Ambulatorio Ipertensione Arteriosa e Patologie Correlate, Matta M., (UOC Medicina Interna, Sacco A., PO Madonna delle Grazie, Matera), Stellitano, E., (UO Medicina, Scordo A., PO 'Tiberio Evoli', Melito Porto Salvo), Russo, F., (UOC Medicina Generale di Rogliano, Caruso A. A., AO di Cosenza), Porreca, E., (UO Medicina Interna e Geriatria, Tana M., D'Annunzio, Università G., Chieti-Pescara), Ferri, C., (Divisione di Medicina Interna e Nefrologia - Ospedale San Salvatore, Cheli P., Dipartimento, Mesva, (Clinica Medica 'Murri', Portincasa P., Dipartimento di Scienze Mediche, e Oncologia Umana, Università degli Studi di Bari), Muscianisi G. (ASP Reggio Calabria, Saline Joniche), Giordani, S., (Dipartimento di Scienze Mediche e Chirurgiche, Stanghellini V., Università degli Studi di Bologna), Sabbà C. (UOC Geriatria e Centro di assistenza e ricerca sovraziendale per le malattie rare, Bari), Mancuso, G., Bartone, M., (UOC Medicina Interna, Calipari D., Presidio, Ospedaliero, ASP di Catanzaro), Arcidiacono, G., (UOC Cardiologia e UTIC, Bellanuova I., Catania), Ferraro M., Marigliano G. (ASP Cosenza), Cozzolino, D., Lampitella, A., (Dipartimento di Internistica Clinica e Sperimentale, Acri V., Seconda Università di Napoli), Galasso, D., Mazzei, F., (RSA Madonna di Porto Gimigliano, Galasso S., Catanzaro), (Azienda Ospedaliera della Provincia di Pavia, Buratti A., UO Medicina Interna, Ospedale, Civile, Casorate, Primo, Pavia), Porta, M., (SC Medicina Interna 1U, Brizzi M. 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(S. C., Ospedale della Valdichiana, Cortona, Usl, 8 Arezzo), (Dipartimento BioMedico di Medicina Interna e Specialistica, Corrao S., Università degli Studi di, Palermo). Simi Young Internists (GIS) Group: Anzaldi M., Bazzini, C., Bianchi, P. I., Boari, B., Buonauro, A., Buttà, C., Buzzetti, E., Calabria, S., Capeci, W., Caradio, F., Carleo, P., Carrabba, M. D., Castorani, L., Cecchetto, L., Cicco, S., Cimini, C., Colombo, B. M., De Giorgi, A., De Vuono, S., Del Corso, L., Denegri, A., Di Giosia, P., Durante Mangoni, E., Falsetti, L., Forgione, A., Giorgini, P., Grassi, D., Grembiale, A., Hijazi, D., Iamele, L., Lorusso, G., Marchese, A., Marra, A. M., Masala, M., Miceli, G., Montebianco Abenavoli, L., Murgia, G., Naccarato, P., Padula, D., Pattoneri, P., Perego, F., Pesce, P., Piano, S., Pinna, M., Pinto, D., Pretti, V., Pucci, G., Raparelli, V., Salinaro, F., Salzano, A., Santilli, F., Scarpini, F., Scicali, R., Sirico, D., Suppressa, P., Talia, M., Tassone, E. J., Torres, D., Vazzana, N., Vecchio, C. R., Vidili, G., Vitale, F., Zaccone, V., Alessandri, C., Serviddio, G., Palange, P, Greco, E, Bruno, G, Averna, M, Giammanco, A, Sposito, P, De Cristofaro, R., De Gennaro, L, Carulli, L, Pellegrini, E, Cominacini, L, Mozzini, C, Pasini, Af, Sprovieri, M, Spagnuolo, V, Cerqua, G, Cerasola, G, Mulé, G, Barbagallo, M, Lo Sciuto, S, Monteverde, A, Saitta, A, Lo Gullo, A, Malatino, L, Cilia, C, Terranova, V, Pisano, M, Pinto, A, Di Raimondo, D, Tuttolomondo, A, Conigliaro, R, Signorelli, S, De Palma, D, Galderisi, M, Cudemo, G, Galletti, F, Fazio, V, De Luca, N, Meccariello, A, Caputo, D, De Donato, Mt, Iannuzi, A, Bresciani, A, Giunta, R, Utili, R, Iorio, V, Adinolfi, Luigi Elio, Sellitto, A, Iuliano, N, Bellis, P, Tirelli, P, Sacerdoti, D, Vanni, D, Iuliano, L, Ciacciarelli, M, Pacelli, A, Palazzuoli, A, Cacciafesta, M, Gueli, N, Lo Iacono, C, Brusco, S, Verrusio, W, Nobili, L., Tarquinio, N., Pellegrini, F, Vincentelli, G. M., Ravallese, F, Santini, C, Letizia, C, Petramala, L, Zinnamosca, L, Minisola, S., Cilli, M, Savoriti, C, Colangelo, L, Falaschi, P, Martocchia, A, Pastore, F., and DURANTE MANGONI, Emanuele
- Subjects
Male ,Risk ,ABI ,ARAPACIS ,Atrial fibrillation ,Myocardial infarction ,Vascular events ,Hematology ,medicine.medical_specialty ,Aged ,Aged, 80 and over ,Ankle Brachial Index ,Atrial Fibrillation ,Female ,Follow-Up Studies ,Humans ,Italy ,Middle Aged ,Predictive Value of Tests ,Prospective Studies ,Survival Analysis ,Vascular Diseases ,Population ,Socio-culturale ,030204 cardiovascular system & hematology ,03 medical and health sciences ,0302 clinical medicine ,atrial fibrillation, ABI, ARAPACIS, myocardial infarction, vascular events ,Interquartile range ,Internal medicine ,myocardial infarction ,vascular events ,80 and over ,Medicine ,Cumulative incidence ,030212 general & internal medicine ,education ,Prospective cohort study ,Stroke ,education.field_of_study ,business.industry ,Hazard ratio ,medicine.disease ,Cardiology ,business ,Settore SECS-S/01 - Statistica - Abstract
SummaryAtrial fibrillation (AF) patients are at high risk for thrombotic and vascular events related to their cardiac arrhythmia and underlying systemic atherosclerosis. Ankle-Brachial Index (ABI) is a non-invasive tool in evaluating systemic atherosclerosis, useful in predicting cardiovascular events in general population; no data are available in AF patients. ARAPACIS is a prospective multicentre observational study performed by the Italian Society of Internal Medicine, analysing association between low ABI (≤0.90) and vascular events in NVAF out- or in-patients, enrolled in 136 Italian centres. A total of 2,027 non-valvular AF (NVAF) patients aged > 18 years from both sexes followed for a median time of 34.7 (interquartile range: 22.0–36.0) months, yielding a total of 4,614 patient-years of observation. Mean age was 73 ± 10 years old with 55% male patients. A total of 176 patients (8.7%) experienced a vascular event, with a cumulative incidence of 3.81%/patient-year. ABI≤ 0.90 was more prevalent in patients with a vascular event compared with patients free of vascular events (32.2 vs 20.2%, p< 0.05). On Cox proportional hazard analysis, ABI≤ 0.90 was an independent predictor of vascular events (hazard ratio (HR): 1.394, 95% confidence interval (CI): 1.042–1.866; p=0.02), vascular death (HR: 2.047, 95% CI: 1.255-3.338; p=0.004) and MI (HR: 2.709, 95%> CI: 1.485-5.083; p=0.001). This latter association was also confirmed after excluding patients with previous MI (HR: 2.901, 95% CI: 1.408-5.990, p=0.004). No association was observed between low ABI and stroke/transient ischaemic attack (p=0.91). In conclusion, low ABI is useful to predict MI and vascular death in NVAF patients and may independently facilitate cardiovascular risk assessment in NVAF patients.Note: The review process for this paper was fully handled by C. Weber, Editor in Chief.Listed in the Supplementary Online Appendix Material which is available online at www.thrombosis-online.com.
- Published
- 2016
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15. Prevalence of peripheral artery disease by abnormal ankle-brachial index in atrial fibrillation: implications for risk and therapy
- Author
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Violi, Francesco, Daví, Giovanni, Hiatt, William, Lip, Gregory Y. H., Corazza, Gino R., Perticone, Francesco, Proietti, Marco, Pignatelli, Pasquale, Vestri, Anna R., Basili, Stefania, Desideri, ARAPACIS Study Investigators Alessandri Cesare (Dipartimento di Scienze e Biotecnologie Medico-Chirurgiche, G., Sapienza-Università di Roma), Serviddio Gaetano (Department of Medical and Surgical Sciences, University of Foggia), Fascetti Stefano (UOC Medicina Generale, USL 12 Viareggio, Toscana), Serra, Pietro, Palange Paolo(UOC Medicina Interna, I, Dipartimento di Sanità Pubblica, e Malattie Infettive, Greco, Eleonora, Bruno Graziella (Medicina, 3, Department of Medical Sciences, Città della Salute e della Scienza, A. O., University of Turin), Averna, Maurizio, Giammanco Antonina (Dipartimento Biomedico di Medicina Interna, e Specialistica (DIBIMIS), Università di Palermo), Sposito Pietro (Azienda Ospedaliera Ospedali Riuniti Papardo Piemonte, Messina), De Cristofaro Raimondo, De Gennaro Leonardo(Istituto di Medicina Interna, e Geriatria, Centro Emostasi, e Trombosi, Gemelli, Policlinico A., Roma), Loria, Paola, Pellegrini Elisa(Medicina Interna ad Indirizzo Metabolico, – NOCSAE Baggiovara, Department of Internal Medicine, Endocrinology, Metabolism and Geriatrics, Università degli Studi di Modena, e Reggio Emilia), Cominacini, Luciano, Mozzini Chiara (Dipartimento di Medicina, Sezione di Medicina Interna, D, Università di Verona), Sprovieri, Mario, Spagnuolo Vitaliano (UOC Medicina d'Urgenza, e PS, Stabilimento Ospedaliero dell'Annunziata, Cosenza), Cerqua Giannantonio (UOC Medicina Interna per l'Urgenza, S Giovanni Addolorata, Ao, Cerasola Giovanni, Mulé Giuseppe (Università degli Studi di Palermo), Barbagallo, Mario, Lo Sciuto Salvatore, Monteverde Alfredo(UOC di Geriatria, e Lungodegenza, Azienda Ospedaliera Universitaria Policlinico, Aoup, Palermo), Saitta, Antonino, Lo Gullo Alberto (UOC Medicina Interna, Università di Messina), Malatino, Lorenzo, Cilia Chiara (Clinica Medica, Ospedale, Cannizzaro, Università degli Studi di Catania), Licata, Giuseppe, Tuttolomondo, Antonino, Conigliaro Roberta (UOC Medicina Interna, e Cardioangiologia, Dipartimento Biomedico di Medicina Interna, e Specialistica, Università degli Studi di Palermo), Pinto, Antonio, Di Raimondo Domenico (UOC Medicina Vascolare, Dipartimento Biomedico di Medicina Interna e Specialistica, (Di. 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Interna Universitaria, - Ospedale San Salvatore, Dipartimento, Mesva, Università, Dell'Aquila, L'Aquila), Portincasa Piero (Clinica Medica 'Murri', Dipartimento di Scienze Mediche, e Oncologia Umana, Università degli Studi di Bari), Muscianisi Giuseppe (ASP Reggio Calabria, Saline Joniche), Giordani, Sara, Stanghellini Vincenzo (Dipartimento di Scienze Mediche, e Chirurgiche, Università degli Studi di Bologna), Sabbà, Carlo, Suppressa Patrizia (UOC Geriatria e Centro di assistenza, e ricerca sovraziendale per le malattie rare, Mancuso, Giuseppe, Bartone, Mosè, Calipari Daniela (UOC Medicina Interna, Presidio, Ospedaliero, ASP di Catanzaro), Arcidiacono, Giuseppe, Bellanuova Ignazio (UOC Cardiologia, e UTIC, Catania), Ferraro, Maria, Scalzo, Antonio, Marigliano Giampietro (ASP Cosenza), Cozzolino, Domenico, Lampitella, Antonio, Acri Vera (Dipartimento di Internistica Clinica, e Sperimentale, Galasso, Domenico, Mazzei, Francesca, Galasso Salvatore (RSA Madonna di Porto Gimigliano, Catanzaro), Buratti Alberto (Azienda Ospedaliera della Provincia di Pavia, UO Medicina Interna, Ospedale, Civile, Casorate, Primo, Porta, Massimo, Brizzi Maria Felice (SC Medicina Interna 1U, Azienda, Ospedaliera, Torino), Fattorini, Annalisa, Sampietro, Francesca, D’Angelo Armando (Coagulation Service and Thrombosis Research Unit, IRCCS Ospedale San Raffaele, Pala, Marco, Fabbian, Fabio, Manfredini Roberto (UOC Clinica Medica, Anna, Azienda Ospedaliera-Universitaria S., Ferrara), Moroni, Carlo, Valente, Lucia, Lopreiato Francesco (Laboratorio di Ecocardiografia-Cardiologia Preventiva, DAI Cuore, e Grossi Vasi, Parente Fernando (UOC Medicina Interna, Granata Massimo (Immunologia Clinica, A, Moia, Marco, Braham Simon (Fondazione IRCCS Ca'Granda, Ospedale Maggiore Policlinico, Rossi, Marco, Pesce Margherita (Dipartimento di Medicina Clinica, e Sperimentale, Università di Pisa), Gentile, Adelina, Catozzo Vania (UO Medicina, Ldp, Loreto, Ferranti, Edoardo, Soldini, Maurizio, Di Napoli Mariarosaria, Baciarello Giacinto (UOC Cardiologia Preventiva, e Riabilitativa, Rancan, Elena, Ageno, Walter, Guasti Luigina (Dipartimento di Medicina Clinica, e Sperimentale, Università, Dell'Insubria, Varese), Ciccaglioni, Antonio, Negri, Silvia, Polselli Marco (Centro Elettro-Stimolazione Cardiaca, Prisco Domenico (SOD Patologia Medica, Aou, Careggi, Firenze), Pignataro Francesca Serena, Pastori, Daniele, Ferro, Domenico, Loffredo, Lorenzo, Cangemi, Roberto, Perri, Ludovica, Polimeni, Licia, Catasca, Elisa, Raparelli, Valeria, Napoleone, Laura, Schillizzi, Marianna, Vicario, Tommasa, Russo, Roberta, Gentile Maria Cristina, Saliola, Mirella, Del Ben Maria, Angelico Francesco (I Clinica Medica, Sapienza-Università di, Roma)., Violi F, Daví G, Hiatt W, Lip GY, Corazza GR, Perticone F, Proietti M, Pignatelli P, Vestri AR, Basili S, ARAPACIS Study Investigators: […, Alessandri C, Serviddio G, Fascetti S, Serra P, Palange P, Greco E, Bruno G, Averna M, Giammanco A, Sposito P, De Cristofaro R, De Gennaro L, Loria P, Pellegrini E, Cominacini L, Mozzini C, Spovieri M, Spagnuolo V, Cerqua G, Cerasola G, Mulé G, Barbagallo M, Lo Sciuto S, Monteverde A, Saitta A, Lo Gullo A, Malatino L, Cilia C, Licata G, Tuttolomondo A, Conigliaro R, Pinto A, Di Raimondo D, Signorelli S, Anzaldi M, De Palma D, Galderisi M, Cudemo G, Galletti F, Fazio V, De Luca N, Meccariello A, Caputo D, De Donato MT, Iannuzi A, Bresciani A, Giunta R, Cimini C, Utili R, Durante M, Emanuele AF, Adinolfi LE, Cristiana S, Restivo L, Bellis P, Tirelli P, Sacerdoti D, Pesce P, Vanni D, Iuliano L, Palazzuoli A, Cacciafesta M, Gueli N, Capeci W, Tarquino N, Pellegrini F, Vincentelli GM, Ravallese F, Santini C, Letizia C, Petramala L, Zinnamosca L, Cilli M, Savoriti C, Falaschi P, Martocchia A, Stefanelli M, Marigliano V, Lo Iacono C, Brusco S, Bertazzoni G, El Halabieh Elias A, Paradiso M, Lizzi EM, Stefano T, Paola B, Cerci S, Ciavolella M, Di Veroli C, Malci F, De Ciocchis A, Abate D, Castellino P, Curto I, Vecchio C, Mannarino E, Pasqualini L, Fattori C, Pende A, Denegri A, Nathan A, Ricchio R, Fimognari FL, Alletto M, Messina S, Sesti G, Arturi F, Gembiale A, Scarpino PE, Carullo G, Pierluigi F, Battaglia G, Vadili G, Atzori S, Delitala G, Davì G, Angelucci E, Simona S, Giancarlo T, De Feudis L, Di Michele D, Fava A, Balsano C, De Ciantis P, Giovambattista D, Camerota A, Migliacci R, Porciello G, Mezzetti M, Gresele P, Vedovati C, Fierro T, Puccetti L, Scarpini F, Bertolotti M, Mussi C, Boddi M, Savino A, Contri S, Saller A, Fabris F, Pesavento R, Filippi L, Vedovetto V, Puato M, Treleani M, Maselli M, Corradin ML, Giantin V, Semplicini A, Minuz P, Calabria S, Romano S, Fantin F, Manica A, Stockner I, Pattis P, Guttman B, Catena C, Colussi GL, Annoni G, Bruni AA, Castagna A, Miceli E, Padula D, Schinco G, Spreafico S, Secchi B, Vanoli M, Casella G, Serra MG, Longo S, Antonaci S, Belfiore A, Frualdo M, Francesco V, Iamele L, Bianco C, Santovito D, Mezzetti A, Cipollone F, Nicolai S, Salvati F, Battista RG, Scozzari F, Muiesan ML, Salvetti M, Bazza A, Picardi A, De Vincentis A, Cosio P, Terzolo M, Fenoglio L, Bracco C, Melchio R, Gentili T, Salvi A, Nitti C, Falsetti L, Gabrielli A, Paglione I, Capucci A, Brambatti M, Sparagna A, Tirotta D, Andreozzi P, Ettorrre E, Cipriani E, Fanelli Fillippo R, Delfino M, Glorioso N, Melis G, Marras G, Matta M, Sacco A, Stellitano E, Scordo A, Russo F, Caruso Assunta A, Porreca E, Santilli F, Tana M, Ferri C, Grassi D, Di Giosia P, Portincasa P, Muscianisi G, Giordani S, Stanghellini V, Sabbà C, Supressa P, Mancuso G, Bartone M, Calipari D, Arcidiacono G, Bellanuova I, Ferraro M, Scalzo A, Marigliano G, Cozzolina D, Lampitella A, Acri V, Galasso D, Mazzei F, Galasso S, Buratti A, Porto M, Brizzi MF, Fattorini A, Sampietro F, D'Angelo A, Pala M, Fabbian F, Manfredini R, Moroni C, Valente L, Lopreiato F, Parente F, Granata M, Moia M, Braham S, Rossi M, Pesce M, Gentile A, Catozzzo V, Ferranti E, Soldini M, Di Napoli M, Baciarello G, Rancan E, Ageno W, Guasti L, Ciccaglioni A, Negri S, Polselli M, Prisco D, Pignataro FS, Pastori D, Ferro D, Loffredo L, Cangemi R, Perri L, Polimeni L, Catasca E, Raparelli V, Napoleone L, Schillizzi M, Vicario T, Russo R, Gentile MC, Saliola M, Del Ben M, Angelico F, Farcomeni A, Di Tanna G, Davi' G, Traisci G, Montebianco Abenavoli L, Grembiale A, Di Minno G, Durante ME, Pattoneri P, Boari B, Fabio G, Perego F, Bianchi Paola I, Angeli A, Colombo BM, Giannelli G, Vidili G, Torres D, Hijazl D, Gatta A, Mannucci Mannuccio P, Licata G., and …]
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Adult ,Male ,Risk ,therapy ,atrial fibrillation ,cardiovascular disease ,peripheral vascular disease ,Aged ,Atrial Fibrillation ,Female ,Humans ,Internal Medicine ,Italy ,Middle Aged ,Peripheral Arterial Disease ,Prevalence ,Registries ,Societies, Medical ,Ankle Brachial Index ,ATRIAL FIBRILLATION ,Cardiology and Cardiovascular Medicine ,Medical ,RISK FACTORS ,cardiovascular diseases ,Societies - Abstract
To the Editor: Nonvalvular atrial fibrillation (NVAF) is the most common sustained arrhythmia encountered in clinical practice and is associated with a 5-fold increased risk for stroke (1). Moreover, patients with NVAF often suffer from atherosclerotic complications such as acute myocardial infarction (AMI) (2). Peripheral artery disease (PAD) is an established marker of systemic atherosclerosis but its prevalence in NVAF is still unclear. We reasoned that inclusion of ankle-brachial index (ABI), which is an established tool for diagnosis of PAD (3), in the CHA2DS2-VASc (4) score would better define the prevalence of vascular disease. To address this issue, the Italian Society of Internal Medicine (SIMI) established an Italian registry documenting ABI in NVAF patients. The Atrial Fibrillation Registry for the ARAPACIS (Ankle-brachial Index Prevalence Assessment: Collaborative Italian Study) study is an independent research project involving all Regional Councils of SIMI. The first objective of the study was to estimate the prevalence of ABI ≤0.90 in NVAF patients. Consecutive patients with NVAF referred to internal medicine wards were eligible for the enrollment. Enrollment started in October 2010 and continued until October 30, 2012. Patients were enrolled if they were 18 years or older and had a diagnosis of NVAF, recording during the qualifying admission/consultation or in the preceding 12 months, and if it was possible to obtain the ABI measurement. Exclusion criteria included the following: acquired or congenital valvular AF, active cancer, disease with life expectancy 0.90 (93% vs. 82%; p < 0.0001). Logistic regression analysis demonstrated that ABI ≤0.90 was significantly associated with a smoking habit (odds ratio [OR]: 1.99; 95% confidence interval [CI]: 1.48 to 2.66; p < 0.0001), diabetes (OR: 1.93; 95% CI: 1.51 to 2.46; p < 0.0001), age class 65 to 74 years (OR: 2.05; 95% CI: 1.40 to 3.07; p < 0.0001), age class ≥75 years (OR: 3.12; 95% CI: 2.16 to 4.61; p < 0.0001), and history of previous transient ischemic attack/stroke (OR: 1.64; 95% CI: 1.20 to 2.24; p = 0.002). Vascular disease, as assessed by the history elements of CHA2DS2VASc score, was recorded in 17.3% of patients; inclusion of ABI ≤0.90 in the definition of vascular disease yielded a total prevalence of 33%. A higher prevalence of vascular disease was detected if ABI ≤0.90 was included in the CHA2DS2VASc score (Fig. 1). CHA2DS2VASc including ABI ≤0.90 was more associated with previous stroke (43%; OR: 1.85; 95% CI: 1.41 to 2.44; p < 0.0001) compared to CHA2DS2VASc with ABI 0.91 to 1.39 (23%; OR: 1.52; 95% CI: 1.10 to 2.11; p = 0.0117). To the best of our knowledge, there is no large-scale study that specifically examined the prevalence of ABI ≤0.90 in NVAF. In our population, 21% had ABI ≤0.90 indicating that NVAF is often associated with systemic atherosclerosis. The CHADS2 has been recently refined with the CHA2DS2-VASc score, which includes vascular disease as documented by a history of AMI, symptomatic PAD, or detection of atherosclerotic plaque in the aortic arch (4). Comparison of vascular prevalence as assessed by CHA2DS2-VASc score and/or ABI ≤0.90 is of interest to define the potentially positive impact of measuring ABI in the management of NVAF patients. Inclusion of ABI ≤0.90 in the definition of vascular disease greatly increased the prevalence of vascular disease, which increased from 17.3% (based on history alone) to 33% (based on ABI) in the entire population. If ABI ≤0.90 was encompassed in the definition of vascular disease of CHA2DS2-VASc score the prevalence of vascular disease increased in every risk class. Inclusion of ABI ≤0.90 in the CHA2DS2-VASc score allowed us to better define the risk profile of NVAF patients with an up-grading of the risk score in each CHA2DS2-VASc score category. This may have important therapeutic implications if the new score could be tested prospectively, as a higher number of NVAF patients would potentially be candidates for an anticoagulant treatment by measuring ABI. A prospective study is, therefore, necessary to validate the risk score of this new definition of vascular disease. In conclusion, this study provides the first evidence that one-fifth of NVAF patients had an ABI ≤0.90, indicating that it may represent a simple and cheap method to better define the prevalence of vascular disease in NVAF.
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- 2013
16. Impact of mitral regurgitation on the outcome of patients treated with CRT-D: Data from the InSync ICD Italian registry
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Giuseppe, Boriani, M. D., H. D., P, Maurizio, Gasparini, † MAURIZIO LANDOLINA, ‡ MAURIZIO LUNATI, MAURO BIFFI, Massimo, Santini, LUIGI PADELETTI, Giulio, Molon, †† GIANLUCA BOTTO, ‡‡ TIZIANA DE SANTO, B. S., and SERGIO VALSECCHI, Gasparini, M., Galimberti, P., Regoli, F., Ceriotti, C., Istituto Clinico Humanitas, Rozzano-, Milano, Lunati, M., Cattafi, G., Magenta, G., Paolucci, M., Vecchi, R., Niguarda, Hospital, Milano, Santini, M., Ricci, R., San Filippo Neri, Roma, Gaita, F., Bocchiardo, M., Didonna, P., Caponi, D., Civile, Hospital, Asti, Tavazzi, L., Landolina, M., Rordorf, R., Petracci, B., Vicentini, A., Savastano, S., Matteo, Pol. S., Pavia, Padeletti, L., Pieragnoli, P., Careggi, Firenze, Vincenti, A., Deceglia, S., Cir ` o, A., Gerardo Dei Tintori, S., Monza(MI), Curnis, A., Mascioli, G., Spedali, Civili, Brescia, Puglisi, A., Bianchi, S., Peraldo, C., Fatebenefratelli, Roma, Sassara, M., Achilli, A., Turreni, F., Rossi, P., Belcolle, Hospital, Viterbo, Perego, Gb., Luca Auxologico, S., Ravazzi, P. A., Diotallevi, P., Antonio e Biagio, Ss., Alessandria, Tritto, M., Mater, Domini, Castellanza, (VA), Carboni, A., Ardissino, D., Gonzi, G., Serra, V., Civile, Parma, Vergara, G., Maria Del Carmine, S., Rovereto, (TN), Boriani, G., Biffi, M., Martignani, C., Diemberger, I., Orsola-Mailpighi, S., Bologna, Luzzi, G., Policlinico, Bari, Laurenzi, F., Camillo, S., Pistis, G., Mauriziano, Torino, Cesario, A., Grassi, G. B., Ostia, (RM), Zanotto, G., Civile, Verona, Orazi, S., Rieti, Ometto, R., Bonanno, C., Bortolo, S., Vicenza, Molon, G., Barbieri, E., Cuore, S., Negrar, (VR), Raviele, A., Gasparini, G., Umbertoi, Mestre, (VE), Botto, G., Luzi, M., Sagone, A., Anna, S., Como, Vado, A., Croce, S., Cuneo, Montenero, A., Multimedica, Giovanni (MI), Sestos., Inama, G., Maggiore, Crema, Sassone, B., Civile, Bentivoglio, (BO), Briedda, M., Zardo, F., Maria, S., Pordenone, E. Bertaglia, Mirano (VE), Proclemer, A., Udine, Zanon, F., Civile, Rovigo, Disertori, M., Gramegna, L., Delgreco, M., Dallafior, D., Chiara, S., Trento, Tomasi, C., Maresta, A., Piancastelli, M., Maria Croci, S., Ravenna, Bridda, A., Martino, S., Belluno, Mantovan, R., C`afoncello, Treviso, Fusco, A., Pederzoli, Peschiera, (VR), Baraldi, P., Agostino, S., Modena, G. Lonardi, Legnago (VR), Rahue, W., Maurizio, S., Bolzano, P. Delise, Conegliano (TV), Menozzi, C., Marianuova, S., Reggioemilia, Babudri, P., Borgoroma, Verona, Marconi, R., Mazzoni, Ascolipiceno, Alfano, G. DeFabrizio F., Moscati, G., Avellino, Barbato, G., Maggiore, Bologna, P. Gelmini, Desenzano (BS), Disabato, Leopoldo, S., Merate, (LC), Ricci, S., Ramazzini, Carpi, (MO), Aulerio, M. D., Biagio, S., Domodossola, (VB), Morgagni, G. L., Latini, R., Macerata, Bardelli, G., Fornaroli, Magenta, (MI), R. Paulichl, F. Tappeiner Merano (BZ), Bernasconi, M., Marzegalli, M., Carlo, S., Neri, G., Montebelluna, Treviso, E. Occhetta, Novara, Bocconcelli, P., Salvatore, S., Pesaro, A. Capucci, Piacenza, Campana, A., Giovanni, S., Salerno, N. Dibelardino, Velletri (RM), Vaglio, A., Giovanni, e Paolo, Venezi, A., Boriani G, Gasparini M, Landolina M, Lunati M, Biffi M, Santini M, Padeletti L, Molon G, Botto G, de Santo T, Valsecchi S, and InSync/InSync ICD Italian Registry Investigators.
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Male ,Mitral Valve Insufficiency ,Socio-culturale ,heart failure ,Comorbidity ,CARDIAC RESYNCHRONIZATION THERAPY ,mitral regurgitation ,Risk Assessment ,Survival Analysis ,Survival Rate ,Treatment Outcome ,Italy ,Risk Factors ,Prevalence ,Humans ,Female ,Registries ,Aged - Abstract
We assessed the influence of clinically significant mitral regurgitation (MR) on clinical-echocardiographic response and outcome in heart failure (HF) patients treated with a biventricular defibrillator (cardiac resynchronization therapy defibrillator [CRT-D]). METHODS AND RESULTS: A total of 659 HF patients underwent successful implantation of CRT-D and were enrolled in a multicenter prospective registry (median follow-up of 15 months). Following baseline echocardiographic evaluation, patients were stratified into two groups according to the severity of MR: 232 patients with more than mild MR (Group MR+: grade 2, 3, and 4 MR) versus 427 patients with mild (grade 1) or no functional MR (Group MR-). On 6- and 12-month echocardiographic evaluation, MR was seen to have improved in the vast majority of MR+ patients, while it remained unchanged in most MR- patients. On 12-month follow-up evaluation, a comparable response to CRT was observed in the two groups, in terms of the extent of left ventricular reverse remodeling and combined clinical and echocardiographic response. During long-term follow-up, event-free survival did not differ between MR+ and MR- patients, even when subpopulations of patients with ischemic heart disease and with dilated cardiomyopathy were analyzed separately. On multivariate analysis, the only independent predictor of death from any cause was the lack of β-blocker use. CONCLUSIONS: This observational analysis supports the use of CRT-D in HF patients with clinically significant MR; MR had no major influence on patient outcome.
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- 2012
17. Prevalence, Characteristics, and Outcomes of COVID-19-Associated Acute Myocarditis
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Enrico Ammirati, Laura Lupi, Matteo Palazzini, Nicholas S. Hendren, Justin L. Grodin, Carlo V. Cannistraci, Matthieu Schmidt, Guillaume Hekimian, Giovanni Peretto, Thomas Bochaton, Ahmad Hayek, Nicolas Piriou, Sergio Leonardi, Stefania Guida, Annalisa Turco, Simone Sala, Aitor Uribarri, Caroline M. Van de Heyning, Massimo Mapelli, Jeness Campodonico, Patrizia Pedrotti, Maria Isabel Barrionuevo Sánchez, Albert Ariza Sole, Marco Marini, Maria Vittoria Matassini, Mickael Vourc’h, Antonio Cannatà, Daniel I. Bromage, Daniele Briguglia, Jorge Salamanca, Pablo Diez-Villanueva, Jukka Lehtonen, Florent Huang, Stéphanie Russel, Francesco Soriano, Fabrizio Turrini, Manlio Cipriani, Manuela Bramerio, Mattia Di Pasquale, Aurelia Grosu, Michele Senni, Davide Farina, Piergiuseppe Agostoni, Stefania Rizzo, Monica De Gaspari, Francesca Marzo, Jason M. Duran, Eric D. Adler, Cristina Giannattasio, Cristina Basso, Theresa McDonagh, Mathieu Kerneis, Alain Combes, Paolo G. Camici, James A. de Lemos, Marco Metra, Ammirati, E, Lupi, L, Palazzini, M, Hendren, N, Grodin, J, Cannistraci, C, Schmidt, M, Hekimian, G, Peretto, G, Bochaton, T, Hayek, A, Piriou, N, Leonardi, S, Guida, S, Turco, A, Sala, S, Uribarri, A, Van De Heyning, C, Mapelli, M, Campodonico, J, Pedrotti, P, Barrionuevo Sanchez, M, Ariza Sole, A, Marini, M, Matassini, M, Vourc'H, M, Cannata, A, Bromage, D, Briguglia, D, Salamanca, J, Diez-Villanueva, P, Lehtonen, J, Huang, F, Russel, S, Soriano, F, Turrini, F, Cipriani, M, Bramerio, M, Di Pasquale, M, Grosu, A, Senni, M, Farina, D, Agostoni, P, Rizzo, S, De Gaspari, M, Marzo, F, Duran, J, Adler, E, Giannattasio, C, Basso, C, Mcdonagh, T, Kerneis, M, Combes, A, Camici, P, De Lemos, J, Metra, M, CarMeN, laboratoire, Niguarda Hospital [Milan, Italy], University of Brescia, University of Texas Southwestern Medical Center [Dallas], Tsinghua University [Beijing] (THU), Center for Systems Biology Dresden [Dresden, Germany] (CSBD), Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Research Unit on Cardiovascular and Metabolic Diseases (ICAN), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Institut de Cardiométabolisme et Nutrition = Institute of Cardiometabolism and Nutrition [CHU Pitié Salpêtrière] (IHU ICAN), CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Universita Vita Salute San Raffaele = Vita-Salute San Raffaele University [Milan, Italie] (UniSR), Cardiovasculaire, métabolisme, diabétologie et nutrition (CarMeN), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Hospices Civils de Lyon (HCL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Hospices Civils de Lyon (HCL), Université de Lyon, unité de recherche de l'institut du thorax UMR1087 UMR6291 (ITX), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Nantes Université - UFR de Médecine et des Techniques Médicales (Nantes Univ - UFR MEDECINE), Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Università degli Studi di Pavia = University of Pavia (UNIPV), Fondazione IRCCS Policlinico San Matteo [Pavia], Hospital Clinico Universitario de Valladolid [Castilla y León, Spain] (HCUV), Instituto de Salud Carlos III [Madrid] (ISC), University of Antwerp (UA), Università degli Studi di Milano = University of Milan (UNIMI), IRCCS Istituto Nazionale dei Tumori [Milano], Bellvitge University Hospital [Barcelona, Spain], Presidio Ospedaliero 'G. Salesi' AN = Ancona Hospital Salesi [Ancona, Italy] (POGSA-AHS), Hôpital Guillaume-et-René-Laennec [Saint-Herblain], Centre hospitalier universitaire de Nantes (CHU Nantes), Thérapeutiques cliniques et expérimentales des infections (EA 3826) (EA 3826), Nantes Université - UFR de Médecine et des Techniques Médicales (Nantes Univ - UFR MEDECINE), King‘s College London, King's College Hospital (KCH), Mater Domini Humanitas Hospital [Castellanza, Italy] (MD2H), Hospital Universitario de La Princesa, Helsinki University Hospital [Finland] (HUS), Hôpital Foch [Suresnes], Ospedale Civile di Baggiovara [Modena, Italy] (OCB), Hospital Papa Giovanni XXIII (Hosp P Giovanni XXIII), Azienda Ospedale Università di Padova = Hospital-University of Padua (AOUP), Ospedale 'Infermi' di Rimini [Rimini, Italy] (OIR), University of California [San Diego] (UC San Diego), University of California (UC), and Università degli Studi di Milano-Bicocca = University of Milano-Bicocca (UNIMIB)
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Adult ,Male ,outcome ,SARS-CoV-2 ,cardiac ,[SDV]Life Sciences [q-bio] ,Left ,COVID-2019 ,MRI ,myocarditis ,Female ,Humans ,Prevalence ,Retrospective Studies ,Stroke Volume ,Ventricular Function, Left ,COVID-19 ,Myocarditis ,[SDV] Life Sciences [q-bio] ,myocarditi ,Physiology (medical) ,Ventricular Function ,Human medicine ,Cardiology and Cardiovascular Medicine - Abstract
Background: Acute myocarditis (AM) is thought to be a rare cardiovascular complication of COVID-19, although minimal data are available beyond case reports. We aim to report the prevalence, baseline characteristics, in-hospital management, and outcomes for patients with COVID-19–associated AM on the basis of a retrospective cohort from 23 hospitals in the United States and Europe. Methods: A total of 112 patients with suspected AM from 56 963 hospitalized patients with COVID-19 were evaluated between February 1, 2020, and April 30, 2021. Inclusion criteria were hospitalization for COVID-19 and a diagnosis of AM on the basis of endomyocardial biopsy or increased troponin level plus typical signs of AM on cardiac magnetic resonance imaging. We identified 97 patients with possible AM, and among them, 54 patients with definite/probable AM supported by endomyocardial biopsy in 17 (31.5%) patients or magnetic resonance imaging in 50 (92.6%). We analyzed patient characteristics, treatments, and outcomes among all COVID-19–associated AM. Results: AM prevalence among hospitalized patients with COVID-19 was 2.4 per 1000 hospitalizations considering definite/probable and 4.1 per 1000 considering also possible AM. The median age of definite/probable cases was 38 years, and 38.9% were female. On admission, chest pain and dyspnea were the most frequent symptoms (55.5% and 53.7%, respectively). Thirty-one cases (57.4%) occurred in the absence of COVID-19–associated pneumonia. Twenty-one (38.9%) had a fulminant presentation requiring inotropic support or temporary mechanical circulatory support. The composite of in-hospital mortality or temporary mechanical circulatory support occurred in 20.4%. At 120 days, estimated mortality was 6.6%, 15.1% in patients with associated pneumonia versus 0% in patients without pneumonia ( P =0.044). During hospitalization, left ventricular ejection fraction, assessed by echocardiography, improved from a median of 40% on admission to 55% at discharge (n=47; P Conclusions: AM occurrence is estimated between 2.4 and 4.1 out of 1000 patients hospitalized for COVID-19. The majority of AM occurs in the absence of pneumonia and is often complicated by hemodynamic instability. AM is a rare complication in patients hospitalized for COVID-19, with an outcome that differs on the basis of the presence of concomitant pneumonia.
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- 2022
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18. Music at All Souls, Oxford : the Lancastrians to the Tudors.
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Cardinall's Musick (Musical group), Henry V, King of England, 1387-1422., Carwood, Andrew., Davy, Richard, ca. 1465-ca. 1507. O Domine caeli terraeque., Dunstable, John, ca. 1390-1453. Descendi in ortum meam., Lambe, Walter, ca. 1451-1499. Nesciens Mater., Merbecke, John, ca. 1510-ca. 1585. Funeral sentences., Parsons, Robert, d. 1572. Ave Maria., Power, Leonel, d. 1445. Credo, no. 5., Sheppard, John, ca. 1515-1558. Christ our paschal lamb., Sturgeon, Nicholas, d. 1454. Salve Mater Domini/Salve templum gratie/-it in nomine Domini., Tallis, Thomas, ca. 1505-1585. Verily, verily, I say unto you., Tye, Christopher, 1497?-1572. Ad te clamamus., and White, Robert, d. 1574. Lamentatio Jeremiae, voices (6)
- Published
- 2000
19. 14th and early 15th century English polyphony.
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Bressler, Charles. Performer, Cooke, John, d. 1419. Alma proles regia/Christi miles/Ab inimicis nostris., Cooke, John, d. 1419. Stella celi., Damett, Thomas. Beata Dei genitrix., Damett, Thomas. Salvatoris Mater pia/O Georgi/Benedictus qui ve-, Damett, Thomas. Salve porta paradisi., Myers, Gordon. Performer, Oberlin, Russell, 1928- Performer, Power, Leonel, d. 1445. Ave Regina Coelorum., Sturgeon, Nicholas, d. 1454. Salve Mater Domini/Salve templum gratie/-it in nomine Domini., and Wolfe, Paul, 1926- Performer
- Published
- 1994
20. Brainstem changes causing reversible RBD in patients with spontaneous intracranial hypotension: a longitudinal neuroimaging study.
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Novellino F, Salsone M, Nicoletti G, Barillari MP, Ferini-Strambi L, and Bono F
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- Humans, Male, Female, Middle Aged, Longitudinal Studies, Adult, Blood Patch, Epidural, Cross-Sectional Studies, Neuroimaging methods, Aged, Polysomnography, REM Sleep Behavior Disorder diagnostic imaging, Magnetic Resonance Imaging, Intracranial Hypotension diagnostic imaging, Intracranial Hypotension therapy, Intracranial Hypotension complications, Brain Stem diagnostic imaging, Brain Stem pathology
- Abstract
Objective: This study aimed to investigate the prevalence of REM sleep behavior disorder (RBD) in patients with spontaneous intracranial hypotension (SIH) and longitudinally assess the effects of epidural blood patch (EBP) treatment on brainstem structures using a neuroimaging approach., Methods: Twenty-two participants (10 SIH patients and 12 controls) underwent 3-Tesla Magnetic Resonance Imaging (MRI) scans. Midbrain and pons areas were measured on T1-weighted scans at baseline in both groups and three months after the first EBP in SIH patients to determine any MRI structural changes. The RBD Single-Questionnaire was used to screen SIH patients with symptoms suggestive of RBD for polysomnographic (PSG) recording., Results: Half of the SIH patients (5/10) exhibited PSG-confirmed RBD. Baseline evaluation revealed deep brain swelling (DBS) on MRI scans in SIH-RBD patients. Following EBP treatment, significant changes in midbrain and pons morphometry were associated with complete clinical remission of RBD. Cross-sectional analysis showed larger midbrain and pons areas in SIH patients (with and without RBD) compared to controls. A midbrain area of 200 mm
2 was identified as a cut-off value distinguishing SIH patients (with and without RBD) from controls individually. Longitudinal analysis demonstrated lower midbrain areas at follow-up compared to baseline in SIH patients., Discussion: The study suggests that brainstem morphometric changes may underlie reversible RBD in SIH patients. Midbrain area measurement could serve as a dynamic biomarker for SIH, particularly in the presence of RBD, offering insights for clinical practice., Competing Interests: Declarations. Ethical approval: All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. Informed consent: Informed consent was obtained from all individual participants included in the study. Conflict of interest: All of the authors reported no financial interests or potential conflicts of interest., (© 2024. Fondazione Società Italiana di Neurologia.)- Published
- 2025
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21. Sentinel role of military dogs in detecting genotoxic agents in the environment during military operations: a pilot study.
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Tidu L, Ciccarelli S, De Sanctis S, Lista F, Ferreri R, Regalbuto E, Grizzi F, Taverna G, Poli A, Bruzzone M, Ceppi M, Roggieri P, and Bolognesi C
- Abstract
During out-of-area military operations, the presence of carcinogenic and/or genotoxic agents has been reported, posing potential health risks to deployed soldiers. Military working dogs (MWDs), trained to detect explosives in the same environments as soldiers, could also serve as sentinel animals, providing valuable information on exposure to hazardous agents. These dogs can help identify environmental and potential adverse effects on their health and that of their handlers, possibly before relevant pathologies manifest. This study aims to evaluate the effectiveness of 33 Italian Army MWDs, deployed to the Lebanese theater for six consecutive months from October 2013 to January 2015, as sentinel animals for detecting exposure to genotoxic agents. The Cytokinesis-Block MicroNucleus (CBMN) assay was used to assess DNA damage, cytostasis, and cytotoxicity in the lymphocytes of these dogs. DNA damage events were specifically scored in once-divided binucleated cells (BCs) and included: a) micronuclei (MNi), indicative of chromosome breakage and/or whole chromosome loss; b) nucleoplasmic bridges (NPBs), a marker of DNA misrepair and/or telomere end-fusions; and c) nuclear buds (NBUDs), which signal the elimination of amplified DNA and/or DNA repair complexes. Our findings revealed an increase in chromosomal damage, assessed before and after deployment, with a statistically significant rise in MNi frequency, thus supporting the use of MWDs as sentinels for human exposure to hazardous agents.
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- 2025
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22. Combining an Anterolateral Complex Procedure With Anterior Cruciate Ligament Reconstruction Reduces Graft Reinjury Without Increasing the Rate of Complications: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
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D'Ambrosi R, Corona K, Cerciello S, Guerra G, Mercurio M, Galasso O, Valli F, Abermann E, and Fink C
- Abstract
Background: Anterolateral ligament reconstruction (ALLR) or lateral extra-articular tenodesis (LET) has been used more frequently in conjunction with anterior cruciate ligament reconstruction (ACLR) in recent years. However, there are still concerns that these procedures may lead to complications such as overconstraint of the lateral compartment, stiffness, infections, tunnel convergence, and other intra- and postoperative complications because of increased surgical time and the need for additional procedures., Hypothesis/purpose: The lateral extra-articular procedure will reduce the failure rate of reconstructed ACLs without increasing the number of complications. The purpose was to compare the complication and graft reinjury rates of 2 main anterolateral complex procedure categories described in the literature-LET and ALLR with isolated ACLR., Study Design: Systematic review and meta-analysis of randomized controlled trials (RTCs); Level of evidence, 2., Methods: The methodology followed the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. The PubMed, Embase, and Cochrane Library databases were searched on March 15, 2024, to identify RTCs comparing isolated ACLR with ACLR + LET or ALLR. The methodological index for nonrandomized studies was employed for the quality evaluation. Complications and graft reinjury rates were recorded and meta-analyzed from all included studies., Results: The initial search yielded 1411 articles. Seventeen studies that included the complication rates (5 in the ALLR group and 12 in the LET group) were included in the review. No significant differences were found in the incidence of complications between the ACLR and ACLR + ALLR groups (Mantel-Haenszel [M-H], 1.20 [95% CI, 0.05-29.30]; P = .91) or between the ACLR and ACLR + LET groups (M-H, 0.39 [95% CI, 0.05-2.98]; P = .36). Significant differences were observed in the failure rate between the ACLR + ALLR group (M-H, 6.78 [95% CI, 1.98-23.22]; P = .002) and the ACLR + LET group (M-H, 3.14 [95% CI, 1.96- 5.04]; P < .00001)., Conclusion: Adding a lateral extra-articular procedure, regardless of the surgical technique, can reduce the failure rate without increasing the number of complications at the mid-term follow-up., Study Registration: PROSPERO (CRD42023458354)., Competing Interests: The authors declared that they have no conflicts of interest in the authorship and publication of this contribution. AOSSM checks author disclosures against the Open Payments Database (OPD). AOSSM has not conducted an independent investigation on the OPD and disclaims any liability or responsibility relating thereto.
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- 2025
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23. An Ascaris lumbricoides infection diagnosed by colonoscopy: A case report and a brief literature review.
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Gigliotti S, Mancuso E, Pantanella M, Manno M, Cosco C, Corea A, Raso NN, Campolo M, Divenuto F, Giancotti A, Marascio N, Doldo P, Quirino A, and Matera G
- Abstract
Background: Ascaris lumbricoides is a nematode that parasitizes the human gastrointestinal tract, and it is the cause of the most common helminthic infections worldwide. It predominates in areas of poor sanitation. Early diagnosis of this intestinal infection is pivotal to avoid its severe and lethal complications such as gut obstruction, volvulus, and perforation., Case Report: A 61-year-old Caucasian female was admitted to the Operational Unit of Gastrointestinal Endoscopic Surgery with abdominal pain, in combination with nausea and vomiting for 2 months. The woman underwent a colonoscopy and surprisingly A. lumbricoides was highlighted. Diagnosis of A. lumbricoides infections is based on the microscopic detection of eggs in stool, thus, patient fecal samples collected were examined by microscopy-based methods, but no eggs were found. Previously, the patient was treated to eradicate H. pylori, using omeprazole, a common proton pump inhibitor., Discussion: Here, we supposed that previous therapy has mitigated the parasite infection severity. In our patient was identified A. lumbricoides, although she came from a medium socio-economic status family and despite, she reported to have never travelled in tropical and subtropical areas. This report highlights the importance of the awareness of ascariasis and that its preventive measures should be included in all health education programs., Competing Interests: Declaration of competing interest The authors declare that they have not conflict of interest., (Copyright © 2025 Elsevier B.V. All rights reserved.)
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- 2025
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24. Isolated ACL Reconstruction Versus Combined ACL and Anterolateral Ligament Reconstruction: Functional Outcomes, Return to Sport, and Survivorship: An Updated Meta-analysis of Comparative Studies.
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Mercurio M, Cofano E, Gasparini G, Galasso O, Familiari F, Sanzo V, Ciolli G, Corona K, and Cerciello S
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Background: Failure, persistent knee instability, and reinjury rates after anterior cruciate ligament (ACL) reconstruction are still concerns. Biomechanical investigations have highlighted the role of the anterolateral ligament (ALL) as a crucial knee stabilizer, and clinical outcomes after combined ACL and ALL reconstruction appear to indicate the success of the procedure., Purpose: To compare the functional outcomes, return-to-sport (RTS) rate, and complications between combined ACL and ALL reconstruction and isolated ACL reconstruction., Study Design: Meta-analysis; Level of evidence, 4., Methods: The PubMed/MEDLINE, Scopus, and Cochrane Central databases were used to search keywords, and a total of 16 studies were included. The data extracted for quantitative analysis included the Tegner activity scale score, Lysholm knee score, International Knee Documentation Committee (IKDC) score, laxity measured using the KT-1000 knee arthrometer, number and types of complications, RTS rate, and survival rate. Random- and fixed-effects models were used for the meta-analysis of pooled mean differences and odds ratios., Results: A total of 2329 patients were identified, 1116 of whom underwent combined ACL and ALL reconstruction and 1213 of whom underwent isolated ACL reconstruction. The mean ages were 25.4 ± 7.2 years and 26.5 ± 7.8 years for the combined ACL and ALL reconstruction and isolated ACL reconstruction groups, respectively. The mean follow-ups were 40.3 ± 21.4 months and 42.5 ± 21.6 months, respectively. Comparable Tegner activity scale ( P = .16), Lysholm knee ( P = .13), and IKDC ( P = .83) scores were found between groups. Significantly greater postoperative knee laxity was found in the isolated ACL reconstruction group (mean difference, -0.44; 95% CI, -0.85 to -0.04; P = .03). The combined ACL and ALL reconstruction group showed a significantly lower rate of graft failure (odds ratio [OR], 0.37; 95% CI, 0.18-0.77; P = .008), a higher RTS rate (OR, 1.41; 95% CI, 1.11-1.80; P = .005), and a higher survival rate (OR, 2.94; 95% CI, 1.97-4.37; P < .001)., Conclusion: Compared with isolated ACL reconstruction, combined ACL and ALL reconstruction yielded comparable functional outcomes but significantly less residual knee laxity and a lower graft failure rate. Patients who underwent combined ACL and ALL reconstruction also had higher RTS and survival rates., Competing Interests: The authors declared that they have no conflicts of interest in the authorship and publication of this contribution. AOSSM checks author disclosures against the Open Payments Database (OPD). AOSSM has not conducted an independent investigation on the OPD and disclaims any liability or responsibility relating thereto.
- Published
- 2025
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25. Endoscopic ultrasound-guided entero-colostomy with lumen-apposing metal stent as a rescue treatment for malignant intestinal occlusion: a multicenter study.
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Neri B, Stigliano S, Biasutto D, Citterio N, Lisotti A, Fusaroli P, Mangiavillano B, Donatelli G, Tonini G, and Di Matteo FM
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- Humans, Female, Aged, Male, Middle Aged, Aged, 80 and over, Retrospective Studies, Adult, Enterostomy methods, Enterostomy adverse effects, Colonic Neoplasms complications, Colonic Neoplasms surgery, Ultrasonography, Interventional, Length of Stay statistics & numerical data, Adenocarcinoma complications, Adenocarcinoma surgery, Treatment Outcome, Intestinal Obstruction etiology, Intestinal Obstruction surgery, Intestinal Obstruction therapy, Stents, Endosonography methods
- Abstract
Background: Surgery is the first-choice treatment for malignant intestinal obstruction (MIO); however, many patients are deemed unfit for surgery. Endoscopic ultrasound-guided entero-colostomy (EUS-EC) with a lumen-apposing metal stent (LAMS) could represent a new treatment option., Methods: Consecutive patients undergoing EUS-EC for MIO from November 2021 to September 2023 at four European tertiary referral centers were retrospectively enrolled. Multidisciplinary meetings determined whether patients were unsuitable for surgery or colonic stent placement, or refused surgery. The primary outcome was technical success of EUS-EC and secondary outcomes were clinical outcome, safety, and hospital stay., Results: 12 patients were enrolled (median age 72.5 [range 42-85] years; 58.3% female). Colonic adenocarcinoma was the primary tumor in 75.0% of patients and 91.7% had stage IV disease. Technical success was 100%. No LAMS misdeployment or other procedural adverse events occurred; three patients (25.0%) had severe post-procedural complications. Clinical success was achieved in 10 patients (83.3%), with 5 (50.0%) resuming chemotherapy after the procedure. Median post-procedural hospital stay was 9 (1-20) days and median overall survival was 47.5 (2-270) days., Conclusions: EUS-EC was a feasible technique and could be considered a possible alternative to standard approaches for MIO in highly selected patients., Competing Interests: The authors declare that they have no conflict of interest., (Thieme. All rights reserved.)
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- 2025
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26. Physiological model-based machine learning for classifying patients with binge-eating disorder (BED) from the Oral Glucose Tolerance Test (OGTT) curve.
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Procopio A, Rania M, Zaffino P, Cortese N, Giofrè F, Arturi F, Segura-Garcia C, and Cosentino C
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- Humans, Models, Biological, Adult, Female, Male, Algorithms, Body Mass Index, Insulin metabolism, Insulin blood, Glycated Hemoglobin analysis, Middle Aged, Machine Learning, Glucose Tolerance Test, Binge-Eating Disorder classification, Binge-Eating Disorder diagnosis, Blood Glucose analysis, Blood Glucose metabolism
- Abstract
Background and Objective: Binge eating disorder (BED) is the most frequent eating disorder, often confused with obesity, with which it shares several characteristics. Early identification could enable targeted therapeutic interventions. In this study, we propose a hybrid pipeline that, starting from plasma glucose data acquired during the Oral Glucose Tolerance Test (OGTT), allows us to classify the two types of patients through computational modeling and artificial intelligence., Methods: The proposed hybrid pipeline integrates a classical mechanistic model of delayed differential equations (DDE) that describes glucose-insulin dynamics with machine learning (ML) methods. Ad hoc techniques, including structural identifiability analysis, have been employed for refining and evaluating the mathematical model. Additionally, a dedicated pipeline for identifying and optimizing model parameters has been applied to obtain reliable estimates. Robust feature extraction and classifier selection processes were developed to ensure the optimal choice of the best-performing classifier., Results: By leveraging parameters estimated from the mechanistic model alongside easily obtainable patient information (such as glucose levels at 30 and 120 min post-OGTT, glycated hemoglobin (Hb1Ac), body mass index (BMI), and waist circumference), our approach facilitates accurate classification of patients, enabling tailored therapeutic interventions., Conclusion: Initial findings, focusing on correctly categorizing patients with BED based on metabolic data, demonstrate promising outcomes. These results suggest significant potential for refinement, including exploration of alternative mechanistic models and machine learning algorithms, to enhance classification accuracy and therapeutic strategies., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 The Authors. Published by Elsevier B.V. All rights reserved.)
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- 2025
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27. Impact of Nursing Interventions via Telephone and Email on the Quality of Life of Patients with Inflammatory Bowel Disease: Preliminary Results of a Comparative Observational Study.
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Mercuri C, Giordano V, Bosco V, Serra N, Spagnuolo R, Nocerino R, Rea T, Colaci C, Guillari A, Doldo P, and Simeone S
- Abstract
Background: Inflammatory bowel disease (IBD), encompassing ulcerative colitis and Crohn's disease, is a heterogeneous chronic condition characterized by periods of relapse and remission. Ulcerative colitis involves inflammation of the colon and rectum mucosa, while Crohn's disease causes deeper, transmural inflammation affecting all four gut layers from the mouth to the anus and can lead to complications such as fistulation. IBD significantly impacts patients' physical and psychological well-being, thus reducing their quality of life (QoL). We aimed to evaluate the effectiveness of nursing intervention facilitated through telephone and email support in improving the quality of life (QoL) of Inflammatory Bowel Disease (IBD) patients., Methods: A pilot comparative observational design with pre-test and post-test assessments was employed, involving 50 participants assigned to either an intervention group (Group A, n = 26) or a control group (Group B, n = 24). Group A received regular telephone consultations and prompt email responses from trained nurses; Group B received standard care. Data were collected at baseline and six months post-intervention (T1) using the Patient-Reported Outcomes Measurement Information System (PROMIS
® ) and Pittsburgh Sleep Quality Index., Results: Group A showed significant improvements in anxiety, depression, fatigue, and sleep quality, with p -values indicating the significance of these findings., Conclusions: Tailored nursing support via remote communication significantly benefits IBD patients by alleviating psychological distress and enhancing their overall well-being, underscoring the importance of integrating such interventions into standard IBD care practices.- Published
- 2024
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28. Endoscopic papillectomy versus surgical ampullectomy for adenomas and early cancers of the papilla: a retrospective Pancreas2000/European Pancreatic Club analysis.
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Hollenbach M, Heise C, Abou-Ali E, Gulla A, Auriemma F, Soares K, Leung G, Schattner MA, Jarnagin WR, Wang T, Caillol F, Giovannini M, Dahel Y, Hackert T, Paik WH, Zerbi A, Nappo G, Napoleon B, Arnelo U, Haraldsson E, Halimi A, Waldthaler A, Will U, Saadeh R, Masaryk V, van der Wiel SE, Bruno MJ, Perez-Cuadrado-Robles E, Deprez P, Sauvanet A, Bolm L, Keck T, Souche R, Fabre JM, Musquer N, Kähler G, Seyfried S, Petrone MC, Mariani A, Zaccari P, Belfiori G, Crippa S, Falconi M, Partelli S, Yilmaz B, Demir IE, Ceyhan GO, Satoi S, Regimbeau JM, Gagniére J, Repici A, Anderloni A, Vollmer C, Casciani F, Del Chiaro M, Oba A, Schulick RD, Berger A, Maggino L, Salvia R, Schemmer P, Wichmann D, Inoue Y, Dinis-Ribeiro M, Laranjo A, Libanio D, Kleemann T, Sandru V, Ilie M, Ahola R, Laukkarinen J, Schumacher B, Albers D, Cúrdia Gonçalves T, Barbier L, Salamé E, Weismüller TJ, Heling D, Alves A, Karam E, Regenet N, Dugic A, Muehldorfer S, Truant S, Caca K, Meier B, Miutescu BP, Tantau M, Birnbaum D, Miksch RC, Wedi E, Salzmann K, Bruzzi M, Lupinacci RM, David P, De Ponthaud C, Schmidt A, Regnér S, and Gaujoux S
- Abstract
Objective: Ampullary neoplastic lesions can be resected by endoscopic papillectomy (EP) or transduodenal surgical ampullectomy (TSA) while pancreaticoduodenectomy is reserved for more advanced lesions. We present the largest retrospective comparative study analysing EP and TSA., Design: Of all patients in the database, lesions with prior interventions, benign histology advanced malignancy (T2 and more), patients with hereditary syndromes and those undergoing pancreatoduodenectomy were excluded. All remaining cases as well as a subgroup of them, after propensity-score matching (nearest-neighbour-method) based on age, gender, anthropometrics, comorbidities, size and histological subtype, were analysed. The median follow-up was 21 months (IQR 10-47) after the primary intervention. Primary outcomes were rates of complete resection (R0) and complications. Groups were compared by Fisher's exact or χ
2 test, Mann-Whitney-U-test and log-rank test for survival., Results: Of 1673 patients in the database, 1422 underwent EP and 251 TSA. Of them, 23.2% were excluded for missing or inconclusive data and 19.8% of patients for prior interventions or hereditary syndromes. Final histology showed in 24.2% of EP and 14.8% of TSA patients a histology other than adenoma or adenocarcinoma while advanced cancers were recorded in 10.9% of EP and 36.6% of TSA patients. Finally, 569 EP and 63 TSA were included in the overall analysis, with a higher rate of more advanced cases and higher R0 resection rates in the TSA groups (90.5% vs 73.1%; p<0.01), with additional ablation in the EP group in 14.4%. Severe adverse event rates were 3.2% (TSA) vs 1.9% (EP). Recurrence after histological R0 resection was 16% (EP) vs 3.2% (TSA; p=0.01), and additional therapy for R1 resection was applied in 67% of the 159 cases. Propensity-score-based matching identified 62 pairs of EP/TSA patients with comparable baseline patient and lesion characteristics. The initial R0-rate was 72.6% (EP) compared with 90.3% (TSA, p=0.02) with recurrences found in 8% (EP) vs 3.2% (TSA; p=0.07); reinterventions were more frequent in the EP group. Overall survival was comparable., Conclusions: The rate of patients with poor indications due to non-neoplastic disease or advanced cancer is still high for both EP and TSA; multiple retreatments were necessary for EP. Although EP can be considered an appropriate primary therapy for certain ampullary adenomas, case selection for both therapies (especially with regard to the best step-up approach) should be studied further., Competing Interests: Competing interests: MH: Honoraria from FUJIFILM for lectures and expert panel. Honoraria from Falk Foundation for lectures. MBruno: Boston Scientific: consultant (money to institution), support for industry and investigator-initiated studies. Cook Medical: consultant (money to institution), support for industry and investigator-initiated studies. Pentax Medical: consultant (money to institution), support for investigator-initiated studies. Mylan: lecturer, support for investigator-initiated studies. ChiRoStim: support for investigator-initiated studies.MDC received a research grant Boston from Haemonetics,INC and he is co-PI of a Boston Scientific sponsored study, (© Author(s) (or their employer(s)) 2024. No commercial re-use. See rights and permissions. Published by BMJ.)- Published
- 2024
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29. The Evaluation of Radiolabeled Prostate-Specific Membrane Antigen Positron Emission Tomography/Computed Tomography for Initial Staging in Intermediate-Risk Prostate Cancer Patients: A Retrospective Multicenter Analysis.
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Evangelista L, Guglielmo P, Giacoppo G, Setti L, Aricò D, Muraglia L, Marzo K, Buffi N, Fasulo V, Rodari M, Jandric J, Salvaggio A, Bonacina M, Lazzeri M, and Lughezzani G
- Abstract
Objectives: The aim of the present study was to assess the performance of radiolabeled-PSMA PET/CT in a cohort of intermediate-risk prostate cancer (PCa) patients for initial staging., Methods: This is a retrospective, multicenter analysis of patients diagnosed with intermediate-risk PCa who were staged using radiolabeled PSMA PET/CT to evaluate the extent of the disease before initiating appropriate treatment. The study included patients from the Nuclear Medicine Units of the Humanitas group between 2021 and 2024. The change in management due to the PSMA PET/CT examination was assessed., Results: A total of 181 patients were enrolled across all three centers. Histopathological assessment from biopsy revealed that 51.4% of patients had favorable PCa, while 48.6% had unfavorable disease. PET/CT was positive for the primary lesions in all patients, but it revealed a positivity rate in 23 (12.7%) patients for nodes and distant organs, with a positivity rate of 0.21 in the unfavorable group and 0.05 in the favorable group ( p < 0.005). Based on follow-up data, diagnostic accuracy was higher than 90% in both the favorable and unfavorable groups for lymph node and distant metastases. The inclusion of PSMA PET/CT in the diagnostic algorithm for patients with intermediate-risk PCa impacted patient management in 24 (13.3%) cases, based on the multidisciplinary team decision., Conclusions: PSMA PET/CT can affect the management of patients with intermediate-risk PCa in up to 13% of cases, mainly for unfavorable diseases. New imaging techniques as a first-line imaging procedure can help to plan the correct therapeutic approach in the intermediate-risk PCa group.
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- 2024
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30. Efficacy of early use of percutaneous stellate ganglion block for electrical storms.
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Baldi E, Dusi V, Rordorf R, Currao A, Compagnoni S, Sanzo A, Gentile FR, Frea S, Gravinese C, Angelini F, Cauti FM, Iannopollo G, De Sensi F, Gandolfi E, Frigerio L, Crea P, Zagari D, Casula M, Binaghi G, Sangiorgi G, Barone L, Persampieri S, Dell'Era G, Patti G, Colombo C, Mugnai G, Tavella D, Notaristefano F, Barengo A, Falcetti R, Girardengo G, D'Angelo G, Tanese N, Sgromo V, De Ferrari GM, and Savastano S
- Subjects
- Humans, Male, Female, Prospective Studies, Treatment Outcome, Middle Aged, Aged, Electrocardiography, Follow-Up Studies, Ventricular Fibrillation therapy, Time Factors, Stellate Ganglion drug effects, Autonomic Nerve Block methods, Registries
- Abstract
Aims: Electrical storm (ES) is a life-threatening condition requiring a rapid management. Percutaneous stellate ganglion block (PSGB) is proved to be safe and effective on top of standard therapy, but no data are available about its early use., Methods and Results: We considered all patients enrolled from 1 July 2017 to 30 April 2024 in the STAR registry (STellate ganglion block for Arrhythmic stoRm), a multicentre, international, observational, prospective registry. We aimed to assess the effectiveness of the first PSGB only. Patients were divided into two groups depending on whether they received PSGB before [early PSGB, often due to antiarrhythmic drug (AAD) contraindication] or after (delayed PSGB) intravenous AADs (AADs other than beta-blockers). We considered 180 PSGB (26 early PSGB and 154 AAD first). In the early PSGB group, we observed a statistically significant reduction of treated arrhythmic events in the hour after PSGB compared with the hour before: 0 (0-0) vs. 4.5 (1-10), P < 0.001, and the extent of the reduction was similar in the early PSGB and delayed PSGB groups [-4.5 (-7 to -2) vs. -2.5 (-3.5 to -1.5), P = ns]. The percentage of patients free from arrhythmias was similar in the two groups up to 12 h after PSGB (81 vs. 84%, P = 0.6, after 1 h; 77 vs. 79%, P = 0.8, at 3 h; and 65 vs. 69%, P = 0.7, after 12 h)., Conclusion: Percutaneous stellate ganglion block is proved to be effective also when used early in the treatment of ES. Due to its rapidity of action, our results may suggest its early use to reduce the number of defibrillations and possibly to reduce the likelihood of a refractory ES., Competing Interests: Conflict of interest: none declared., (© The Author(s) 2024. Published by Oxford University Press on behalf of the European Society of Cardiology. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.)
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- 2024
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31. Early Prone Positioning As a Rescue Therapy for Moderate-to-severe Primary Graft Dysfunction After Bilateral Lung Transplant.
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Sella N, Pettenuzzo T, Congedi S, Bisi M, Gianino G, De Carolis A, Bertoncello CA, Roccaforte M, Zarantonello F, Persona P, Petranzan E, Roca G, Biamonte E, Carron M, Dell'Amore A, Rea F, Boscolo A, and Navalesi P
- Abstract
Objectives: Primary graft dysfunction (PGD) affects survival after lung transplant (LT). The current hypothesis was that prone positioning (PP), proposed as a rescue maneuver to treat refractory hypoxemia due to PGD, may improve LT outcomes, especially when applied early., Design: Bilateral LT recipients developing moderate-to-severe PGD within 24 hours from intensive care unit admission were enrolled. From January 2020 to November 2021, patients developing PGD after LT were turned prone between 24 and 48 hours after diagnosis, only in case of radiological or oxygenation worsening ("late PP" group). After November 2021, patients were routinely turned prone within 24 hours from PGD diagnosis ("early PP"). A propensity score-weighted analysis, adjusted for clinically relevant covariates, was applied., Setting: Intensive care unit., Participants: Bilateral LT recipients., Interventions: Early PP, late PP, or supine position., Measurements and Main Results: 130 LT patients were screened and 67 were enrolled. A total of 25 (37%) recipients were treated in the supine position, 24 (36%) in early PP, and 18 (27%) in late PP. After propensity score weighting, both supine treatment (estimated effect for 1 ventilator-free day = 8.23, standard error: 2.97, p = 0.007) and early PP treatment (estimated effect = 9.42, standard error: 2.59, p < 0.001) were associated with greater 28-day ventilator-free days than late PP treatment (reference). Compared with late PP, early PP was also associated with better oxygenation, driving pressure, and static respiratory system compliance. Compared with supine recipients, the early PP group showed better oxygenation at 72 hours after PGD diagnosis., Conclusions: Early PP in LT recipients with moderate-to-severe PGD seems to be associated with better 28-day ventilator-free days, oxygenation, and driving pressure than late PP., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 The Authors. Published by Elsevier Inc. All rights reserved.)
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- 2024
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32. Early intervention and cumulative life course impairment in psoriasis: a review.
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Arancio LMH, D'Amico D, Dastoli S, Fiorella CS, Manfredini M, Moretta G, Paolino G, Levi A, Di Fino S, Zucchi B, and Piaserico S
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- Humans, Risk Factors, Adaptation, Psychological, Social Stigma, Comorbidity, Psoriasis psychology, Psoriasis complications, Psoriasis therapy, Quality of Life
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Psoriasis is a chronic, systemic, inflammatory disease affecting the skin, joints and other organs. Psoriasis negatively affects patients' quality of life, causing social anxiety and negative coping, thus determining a cumulative life course impairment (CLCI). The concept of CLCI in psoriasis is reinforced by the understanding that psoriasis-associated comorbidities and stigma accumulate over a patient's life course, resulting from an interaction between the burden of stigmatization, physical and psychological comorbidities, coping strategies and external factors. The concept may help identify more vulnerable patients and facilitate more appropriate treatment decisions or earlier referrals. Although some potential risk factors for CLCI have been clarified, no all-encompassing screening tools are available. Patients at risk for CLCI should be identified by applying clinical, personal and psychosocial indicators and predictors individually. Early intervention in psoriasis treatment could improve long-term patient outcomes and modify the disease course. However, more research is needed to clearly define what constitutes 'early' intervention and to identify the most effective strategies for implementation. From a preventive point of view, it is helpful to identify early interventions aimed at reducing the risk of CLCI and establishing a new life course trajectory in patients with psoriasis. This review summarizes the latest developments in CLCI and psoriasis, highlighting knowledge gaps and future directions to make control of CLCI a possible goal for therapies., Competing Interests: Conflicts of interest L.M.H.A. has been a consultant and/or speaker for AbbVie, Almirall, Pfizer, Novartis and Janssen. D.D. has received fees from AbbVie, Janssen and Eli Lilly. S.D. has been a consultant or speaker for AbbVie, Almirall, Amgen, LEO Pharma and Novartis. G.M. has received fees from AbbVie, LEO Pharma, Sanofi and Eli Lilly. G.P. has received fees from AbbVie, Janssen and Pierre Fabre Pharma. S.P. has been a consultant and/or speaker for AbbVie, Almirall, Amgen, Eli Lilly, Janssen, LEO Pharma, Merck Sharp & Dohme, Novartis, Pfizer, Sandoz and UCB. C.S.F. and M.M. have no conflicts of interest to declare. A.L., S.D.F. and B.Z. are full-time employees of AbbVie and may hold AbbVie stock and/or stock options., (© The Author(s) 2024. Published by Oxford University Press on behalf of British Association of Dermatologists.)
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- 2024
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33. Efficacy of percutaneous stellate ganglion block according to ventricular arrhythmia cycle length: A post hoc subanalysis of the STAR study.
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Baldi E, Rordorf R, Compagnoni S, Dusi V, Sanzo A, Gentile FR, Frea S, Gravinese C, Cauti FM, Iannopollo G, De Sensi F, Gandolfi E, Frigerio L, Crea P, Zagari D, Casula M, Sangiorgi G, Persampieri S, Dell'Era G, Patti G, Colombo C, Mugnai G, Notaristefano F, Barengo A, Falcetti R, Girardengo G, D'Angelo G, Tanese N, Currao A, Sgromo V, De Ferrari GM, and Savastano S
- Abstract
Background: Data on the predictors of percutaneous stellate ganglion block (PSGB) efficacy in electrical storm are scanty., Objective: We aimed to assess whether PSGB efficacy is influenced by the arrhythmia type and cycle length before the procedure., Methods: This is a subanalysis of the multicenter STAR study. The population was stratified into 3 groups according to the median cycle length of the latest ventricular arrhythmia before PSGB: ventricular fibrillation (VF), fast ventricular tachycardia (VT), and slow VT. The primary outcome was the number of treated arrhythmic episodes (with antitachycardia pacing or direct current shocks) in the hour immediately after PSGB compared with the hour before., Results: We considered 139 PSGBs from 112 patients divided into VF (51 procedures), fast VT (44 procedures, VT cycle <375 ms), and slow VT (44 procedures, VT cycle ≥375 ms). The number of treated arrhythmic episodes in the hour after every PSGB was significantly lower compared with the hour before in all groups (VF: 0 [0-1] vs 5 [2-8], P < .001; fast VT: 0 [0-0] vs 1 [0-6.5], P < .001; slow VT: 0 [0-0] vs 1 [0-4.5], P = .001). In analyzing the reduction of the number of antitachycardia pacing sequences or direct current shocks from the hour before to the hour after PSGB, a significant trend was observed across the groups (Jonckheere-Terpstra trend P < .001), and a significant difference was observed in comparing slow VT vs VF and fast VT vs VF but not in comparing slow VT vs fast VT. VF was independently associated with the probability of reduction of treated events after PSGB., Conclusion: PSGB is an effective treatment of electrical storm in patients with all types of ventricular arrhythmias. However, its effectiveness was more pronounced in patients with VF., Competing Interests: Disclosures The authors have no conflicts of interest to disclose., (Copyright © 2024 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.)
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- 2024
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34. Endoluminal radiofrequency ablation with stenting versus stenting alone in patients with malignant biliary obstruction: a meta-analysis of randomized trials.
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Ramai D, Maida M, Smith ER, Wang Y, Spadaccini M, Previtera M, Chandan S, Huang Y, Tokmak S, Bhandari P, DuBroff J, Ko C, Morris JD, Marasco G, Crinó SF, Facciorusso A, Mangiavillano B, and Khashab MA
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Background: Endoluminal radiofrequency ablation (RFA) is a palliative treatment for patients suffering from malignant biliary obstruction (MBO). We aimed to conduct a meta-analysis to evaluate the impact of RFA on stent patency, patient survival, and adverse events., Methods: Major databases were searched through December 2023 for patients who had undergone stenting with or without RFA for extrahepatic MBO. A random-effects model was used for analysis, with results expressed as relative risk ratios (RRs) with 95%CIs., Results: Nine RCTs involving 750 subjects with MBO (374 RFA plus stent vs. 376 stent only) were included. Meta-analysis revealed similar risks of stent patency at 3 months (RR 1.01, 95%CI 0.92-1.11; I
2 = 4%) for RFA plus stenting vs. stent only. Meta-analysis showed improved survival at 6 months (RR 0.84, 95%CI 0.73-0.96; I2 = 21%; P = 0.01) for RFA plus stenting vs. stent only. Subgroup analysis comparing plastic vs. uncovered metal stents showed that stent patency was unaffected at 3 months (RR 1.06, 95%CI 0.91-1.23; I2 = 17%). Subgroup analysis showed that patients with cholangiocarcinoma experienced an overall survival benefit with RFA plus stenting vs. stenting alone ( P < 0.001); however, stent patency remained unaffected ( P = 0.08). An increased incidence of cholecystitis was noted with RFA plus stenting vs. stenting alone (5.1% [95%CI 3.1%-7.8%] vs. 0.3% [95%CI 0.01%-1.5%], respectively)., Conclusion: Combining endoluminal RFA and stenting may improve overall survival in patients with MBO. RFA did not significantly impact stent patency., Competing Interests: S.F. Crinò has received a grant from Steris Endoscopy. B. Mangiavillano has received lecture fees from Taewoong. M. Khashab is a consultant for Boston Scientific, Medtronic, Olympus, Pentax, GI Supply, and Apollo; he receives research support from Boston Scientific and royalties from Elsevier and UpToDate. D. Ramai, M. Maida, E.R. Smith, Y. Wang, M. Spadaccini, M. Previtera, S. Chandan, Y. Huang, S. Tokmak, P. Bhandari, J. Dubroff, C. Ko, J.D. Morris, G. Marasco, and A. Facciorusso declare that they have no conflict of interest., (Thieme. All rights reserved.)- Published
- 2024
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35. Cascade of care for TB infection in persons newly diagnosed with HIV in Italy.
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Matteelli A, Formenti B, Cimaglia C, Visconti M, di Rosario G, Russo G, Calcagno A, Gori A, Coppola N, Francisci D, Andreoni M, Foti G, Cristini F, Bassi P, Luzzati R, Scaggiante R, Torti C, Lapadula G, Cuzzi G, Antinori A, Gagliardini R, Navarra A, Girardi E, and Goletti D
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- 2024
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36. Enhancing ICU care with nurse-written diaries.
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Bosco V, Mercuri C, Giordano V, Froio AM, Commisso D, Nocerino R, Guillari A, Rea T, Mastrangelo H, Uchmanowicz I, and Simeone S
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- Humans, Female, Middle Aged, Male, Adult, Aged, Writing, Nursing Staff, Hospital psychology, Nonverbal Communication, Critical Care psychology, Critical Illness psychology, Critical Illness nursing, Intensive Care Units, Qualitative Research, Diaries as Topic, Critical Care Nursing
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Background: Patient diaries are a supportive intervention aiding intensive care unit (ICU) survivors and their families post-critical illness. Despite their growing acceptance, ICU diary usage varies across settings., Aim: This study explored themes in nurse-written ICU diaries and their impact on nursing work and communication., Study Design: This qualitative study employed an interpretative narrative methodology to explore the experiences of ICU nurses. The narrative approach enabled the synthesis of diverse events and impressions into coherent stories, facilitating a deeper understanding of participants' perspectives. Data collection involved thematic analysis of diaries following Braun and Clarke's methodology. The analysis included familiarization, coding, theme identification and validation by the research team. The findings were reviewed by participants and translated into English using the WHO's cultural adaptation guidelines, ensuring reliability and credibility in the study's outcomes., Results: The sample consisted of 28 ICU nurses, each with professional experience ranging from 1 to 23 years. The hospitalized subjects for whom our sample wrote the diary consist of 13 participants aged 23-79 years. Two main themes emerged from the analysis: (1) simplifying the intensive care situation with specific minimization strategies and (2) attention to nonverbal communication., Conclusions: This study highlights the role of nurse-written ICU diaries in making the ICU environment more understandable and less intimidating for patients. Nurse-written ICU diaries contribute to improved communication and emotional support within the ICU environment. Further research is needed to explore these effects more fully and to assess the broader implications of ICU diaries on patient outcomes., Relevance to Clinical Practice: Nurse-written intensive care unit (ICU) diaries have a significant impact on both patient care and nursing practice in ICUs. ICU diaries serve as a crucial tool for enhancing communication, emotional support and empathetic care within these high-stress environments. By simplifying complex medical information and focusing on nonverbal communication, nurses can make the ICU experience more comprehensible and less intimidating for patients. This approach reduces patient anxiety and psychological stress while fostering a stronger nurse-patient relationship, ultimately improving care quality., (© 2024 The Author(s). Nursing in Critical Care published by John Wiley & Sons Ltd on behalf of British Association of Critical Care Nurses.)
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- 2024
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37. The 1st i-EUS consensus on the management of pancreatic fluid collections - Part 2.
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Capurso G, Coluccio C, Rizzo GEM, Crinò SF, Cucchetti A, Facciorusso A, Hassan C, Amato A, Auriemma F, Bertani H, Binda C, Cipolletta F, Forti E, Fugazza A, Lisotti A, Maida M, Sinagra E, Sbrancia M, Spadaccini M, Tacelli M, Vanella G, Anderloni A, Fabbri C, and Tarantino I
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- Humans, Consensus, Italy, Pancreatitis therapy, Pancreatitis, Acute Necrotizing therapy, Pancreatitis, Acute Necrotizing diagnostic imaging, Pancreatitis, Acute Necrotizing surgery, Ultrasonography, Interventional, Drainage methods, Endosonography, Pancreatic Pseudocyst therapy, Pancreatic Pseudocyst diagnostic imaging, Pancreatic Pseudocyst surgery, Stents
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Pancreatic fluid collections (PFCs), including pancreatic pseudocysts (PPs) and walled-off pancreatic necrosis (WON), are common complications of pancreatitis and pancreatic surgery. Historically, the treatment of these conditions has relied on surgical and radiological approaches. The treatment of patients with PFCs has already focused toward an endoscopy-based approach, and with the development of dedicated lumen-apposing metal stents (LAMS), it has almost totally shifted towards interventional Endoscopic Ultrasound (EUS)-guided procedures. However, there is still limited consensus on several aspects of PFCs treatment within the multidisciplinary management. The interventional endoscopy and ultrasound (i-EUS) group is an Italian network of clinicians and scientists with special interest in biliopancreatic interventional endoscopy, especially interventional EUS. This manuscript focuses on the second part of the results of a consensus conference organized by i-EUS, with the aim of providing evidence-based guidance on several intra- and post-procedural aspects of PFCs drainage, such as clinical management and follow-up., Competing Interests: Conflict of Interest There is no financial support to this study. Chiara Coluccio: Lecturer per steris. Cecilia Binda: Lecturer fees for Fujifilm, Steris, Q3 Medical, Boston Scientific. Andrea Lisotti received consultancy from Boston Scientific. Giuseppe Vanella: lecture fees from Boston Scientific and travel grants from Euromedical. Carlo Fabbri: consultant per Boston scientific, Lecturer per steris e Q3 medical All the other authors have no conflict of interest to declare., (Copyright © 2024. Published by Elsevier Ltd.)
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- 2024
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38. Correction: Outcomes of lumen apposing metal stent placement in patients with surgically altered anatomy: Multicenter international experience.
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Mangiavillano B, Ramai D, Kahaleh M, Tyberg A, Shahid H, Sarkar A, Samanta J, Dhar J, Bronswijk M, Van der Merwe S, Kouanda A, Ji H, Dai SC, Deprez P, Vargas-Madrigal J, Vanella G, Leone R, Arcidiacono PG, Robles-Medranda C, Alcivar Vasquez J, Arevalo-Mora M, Fugazza A, Ko C, Morris J, Lisotti A, Fusaroli P, Dhaliwal A, Mutignani M, Forti E, Cottone I, Larghi A, Rizzatti G, Galasso D, Barbera C, Di Matteo FM, Stigliano S, Binda C, Fabbri C, Pham KD, Di Mitri R, Amata M, Crinó SF, Ofosu A, De Luca L, Al-Lehibi A, Auriemma F, Paduano D, Calabrese F, Gentile C, Hassan C, Repici A, and Facciorusso A
- Abstract
[This corrects the article DOI: 10.1055/a-2411-1814.]., Competing Interests: Conflict of Interest Benedetto Mangiavillano has no conflict of interest regarding this paper but is consultant for Taewoong medical., (The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).)
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- 2024
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39. Long-term outcome of autologous haematopoietic stem cell transplantation in patients with systemic sclerosis: a comparison with patients treated with rituximab and with traditional immunosuppressive agents.
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Del Papa N, Cavalli S, Rindone A, Onida F, Saporiti G, Minniti A, Pellico MR, Iannone C, Trignani G, D'Angelo N, Sette M, Greco R, Vitali C, and Caporali R
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- Humans, Female, Male, Middle Aged, Retrospective Studies, Adult, Treatment Outcome, Respiratory Function Tests, Follow-Up Studies, Rituximab therapeutic use, Hematopoietic Stem Cell Transplantation methods, Scleroderma, Systemic drug therapy, Scleroderma, Systemic therapy, Scleroderma, Systemic mortality, Transplantation, Autologous methods, Immunosuppressive Agents therapeutic use
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Background: Autologous haematopoietic stem cell transplantation (AHSCT) is more effective than conventional immunosuppressive therapies (CIT) in improving the outcome of patients with rapidly progressive diffuse cutaneous systemic sclerosis (dcSSc). So far, there is still a paucity of data comparing AHSCT with rituximab (RTX). Aim of the study is to retrospectively compare, in patients with dcSSc, the effectiveness of AHSCT with that of RTX and CIT., Methods: Thirty-five dcSSc AHSCT-treated patients were compared with 29 and 36 matched cases treated with RTX and CIT, respectively. The patients were followed up for 5 years by assessing selected outcome measures every year. Overall survival, modified Rodnan skin score (mRSS), lung function tests (FVC and DLCO), and the revised EUSTAR Activity Index (REAI) were the outcome measures chosen to evaluate the therapy efficacy., Results: AHSCT was significantly more effective than RTX and CIT in prolonging survival, inducing a rapid reduction of the mRSS and REAI and maintaining the baseline level of lung function tests for a longer time. RTX therapy was also superior to CIT in reducing REAI, mRSS and in saving lung function., Conclusion: AHSCT is more effective than both RTX and CIT in prolonging survival and inducing prolonged remission in patients with rapidly progressive dcSSc., (© 2024. The Author(s).)
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- 2024
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40. Spatial-transcriptomic profiling: a new lens for understanding myelofibrosis pathophysiology.
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Peroni E, Calistri E, Amato R, Gottardi M, and Rosato A
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- Humans, Gene Expression Profiling, Animals, Transcriptome genetics, Primary Myelofibrosis genetics, Primary Myelofibrosis pathology, Primary Myelofibrosis metabolism
- Abstract
Myelofibrosis (MF) is a complex myeloproliferative neoplasm characterized by abnormal hematopoietic stem cell proliferation and subsequent bone marrow (BM) fibrosis. First documented in the late 19th century, MF has since been extensively studied to unravel its pathophysiology, clinical phenotypes, and therapeutic interventions. MF can be classified into primary and secondary forms, both driven by mutations in genes such as JAK2, CALR, and MPL, which activate the JAK-STAT signaling pathway. These driver mutations are frequently accompanied by additional non-driver mutations in genes like TET2, SRSF2, and TP53, contributing to disease complexity. The BM microenvironment, consisting of stromal cells, extracellular matrix, and cytokines such as TGF-β and TNF-α, plays a critical role in fibrosis and aberrant hematopoiesis. Clinically, MF manifests with symptoms ranging from anemia, splenomegaly, and fatigue to severe complications such as leukemic transformation. Splenomegaly, caused by extramedullary hematopoiesis, leads to abdominal discomfort and early satiety. Current therapeutic strategies include JAK inhibitors like Ruxolitinib, which target the JAK-STAT pathway, alongside supportive treatments such as blood transfusions, erythropoiesis-stimulating agents and developing combinatorial approaches. Allogeneic hematopoietic stem cell transplantation remains the only curative option, though it is limited to younger, high-risk patients. Recently approved JAK inhibitors, including Fedratinib, Pacritinib, and Momelotinib, have expanded the therapeutic landscape. Spatially Resolved Transcriptomics (SRT) has revolutionized the study of gene expression within the spatial context of tissues, providing unprecedented insights into cellular heterogeneity, spatial gene regulation, and microenvironmental interactions, including stromal-hematopoietic dynamics. SRT enables high-resolution mapping of gene expression in the BM and spleen, revealing molecular signatures, spatial heterogeneity, and pathological niches that drive disease progression. These technologies elucidate the role of the spleen in MF, highlighting its transformation into a site of abnormal hematopoietic activity, fibrotic changes, and immune cell infiltration, functioning as a "tumor surrogate." By profiling diverse cell populations and molecular alterations within the BM and spleen, SRT facilitates a deeper understanding of MF pathophysiology, helping identify novel therapeutic targets and biomarkers. Ultimately, integrating spatial transcriptomics into MF research promises to enhance diagnostic precision and therapeutic innovation, addressing the multifaceted challenges of this disease., (© 2024. The Author(s).)
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- 2024
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41. Outcomes of lumen apposing metal stent placement in patients with surgically altered anatomy: Multicenter international experience.
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Mangiavillano B, Ramai D, Kahaleh M, Tyberg A, Shahid H, Sarkar A, Samanta J, Dhar J, Bronswijk M, Van der Merwe S, Kouanda A, Ji H, Dai SC, Deprez P, Vargas-Madrigal J, Vanella G, Roberto L, Arcidiacono PG, Robles-Medranda C, Alcivar Vasquez J, Arevalo-Mora M, Fugazza A, Ko C, Morris J, Lisotti A, Fusaroli P, Dhaliwal A, Mutignani M, Forti E, Cottone I, Larghi A, Rizzatti G, Galasso D, Barbera C, Di Matteo FM, Stigliano S, Binda C, Fabbri C, Pham KD, Di Mitri R, Amata M, Crinó SF, Ofosu A, De Luca L, Al-Lehibi A, Auriemma F, Paduano D, Calabrese F, Gentile C, Hassan C, Repici A, and Facciorusso A
- Abstract
Background and study aims Although outcomes of lumen-apposing metal stents (LAMS) placement in native anatomy have been reported, data on LAMS placement in surgically altered anatomy (SAA) are sparse. We aimed to assess outcomes of LAMS placement in patients with SAA for different indications. Patients and methods This was an international, multicenter, retrospective, observational study at 25 tertiary care centers through November 2023. Consecutive patients with SAA who underwent LAMS placement were included. The primary outcome was technical success defined as correct placement of LAMS. Secondary outcomes were clinical success and safety. Results Two hundred and seventy patients (125 males; average age 61 ± 15 years) underwent LAMS placement with SAA. Procedures included EUS-directed transgastric ERCP (EDGE) and EUS-directed transenteric ERCP (EDEE) (n = 82), EUS-guided entero-enterostomy (n = 81), EUS-guided biliary drainage (n = 57), EUS-guided drainage of peri-pancreatic fluid collections (n = 48), and EUS-guided pancreaticogastrostomy (n = 2). Most cases utilized AXIOS stents (n = 255) compared with SPAXUS stents (n = 15). Overall, technical success was 98%, clinical success was 97%, and the adverse event (AE) rate was 12%. Using AGREE classification, five events were rated as Grade II, 21 events as Grade IIIa, and six events as IIIb. No difference in AEs were noted among stent types ( P = 0.52). Conclusions This study shows that placement of LAMS is associated with high technical and clinical success rates in patients with SAA. However, the rate of AEs is noteworthy, and thus, these procedures should be performed by expert endoscopists at tertiary centers., Competing Interests: Conflict of Interest Benedetto Mangiavillano has no conflict of interest regarding this paper but is consultant for Taewoong medical., (The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).)
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- 2024
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42. Factors Associated With a Successful Return to Performance After Anterior Cruciate Ligament Reconstruction: A Multiparametric Evaluation in Soccer Players.
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Mercurio M, Cerciello S, Corona K, Guerra G, Simonetta R, Familiari F, Galasso O, and Gasparini G
- Abstract
Background: Anterior cruciate ligament reconstruction (ACLR) is highly recommended in patients with ACL deficiency who must perform at a high physical level. A combination of functional and psychological outcome measures is necessary to provide a comprehensive evaluation of functional status after successful return to sport after ACLR., Purpose: To identify factors associated with higher functional outcomes among soccer players who had returned to full sports participation after ACLR., Study Design: Cohort study; Level of evidence, 3., Methods: A total of 168 out of 231 patients who underwent primary unilateral arthroscopic anatomic single-bundle ACLR were available at follow-up. Postoperatively, knee function, generic health outcomes, and psychological impact were assessed using the International Knee Documentation Committee (IKDC), the Knee injury and Osteoarthritis Outcome Score (KOOS), the Lysholm Knee Scoring Scale, the 12-item Short Form Health Survey (SF-12), and the ACL-Return to Sport after Injury scale., Results: After a mean follow-up of 35.5 ± 22.6 months, 85% of soccer players returned to performance. Midfielder position was associated with a better SF-12 Physical Component Summary (PCS) score ( P = .013), IKDC ( P = .003), total KOOS ( P < .001), KOOS Symptoms ( P = .004), KOOS Pain ( P = .029), KOOS Activities of Daily Living (ADL) ( P = .044), KOOS Sport and Recreation (Sport/Rec) ( P = .001), KOOS Quality of Life (QoL) ( P < .001), and Lysholm score ( P = .008). Playing only on natural grass was associated with lower SF-12 PCS scores ( P = .003), total KOOS ( P = .001), and KOOS Sport/Rec ( P = .011). Playing only on artificial turf was associated with lower Lysholm score ( P = .018) and total KOOS ( P = .014). The contact mechanism was associated with higher IKDC ( P = .044) and KOOS QoL ( P = .048), and injury affecting the dominant limb was associated with lower SF-12 Mental Component Summary scores ( P = .012). Playing at a nonprofessional level was associated with lower total KOOS ( P = .028), KOOS Symptoms ( P = .002), KOOS ADL ( P = .033), and KOOS Sport/Rec ( P = .016)., Conclusion: Professional soccer players and the midfielder position are associated with better functional scores upon returning to the sport. A history of noncontact ACL injury and playing on a single type of surface are associated with lower functional outcomes upon returning to the sport. Lower mental health scores can be expected after injury of the dominant limb., Competing Interests: The authors declared that they have no conflicts of interest in the authorship and publication of this contribution. AOSSM checks author disclosures against the Open Payments Database (OPD). AOSSM has not conducted an independent investigation on the OPD and disclaims any liability or responsibility relating thereto., (© The Author(s) 2024.)
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- 2024
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43. Palliation of Gastric Outlet Obstruction in Case of Biliary Obstruction-A Retrospective, Multicenter Study: The B-GOOD Study.
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Fugazza A, Andreozzi M, Binda C, Lisotti A, Tarantino I, Vila JJ, Robles Medranda C, Amato A, Larghi A, Perez Cuadrado Robles E, Aragona G, Di Matteo F, Badas R, Hassan C, Barbera C, Mangiavillano B, Crinò S, Colombo M, Fabbri C, Fusaroli P, Facciorusso A, Anderloni A, Spadaccini M, and Repici A
- Abstract
Background: EUS-guided gastroenterostomy (EUS-GE) is a novel and effective procedure for the management of malignant gastric outlet obstruction (GOO) with more durable results when compared to enteral stenting (ES). However, data comparing EUS-GE to ES in patients already treated with EUS-guided choledocoduodenostomy (EUS-CDS) for distal malignant biliary obstruction (DMBO) are lacking. We aimed to compare outcomes of EUS-GE and ES for the palliation of GOO in this specific population of patients., Methods: A multicenter, retrospective analysis of patients with DMBO treated by EUS-CDS and subsequent GOO treated by EUS-GE or ES from 2016 to 2021 was conducted. Primary outcomes were overall AEs rate and dysfunction of the EUS-CDS after GOO treatment. Secondary outcomes included clinical success, technical success, procedure duration, length of hospital stay and relapse of GOO symptoms., Results: A total of 77 consecutive patients were included in the study: 25 patients underwent EUS-GE and 52 underwent ES. AEs rate and patency outcomes of the EUS-CDS after GOO treatment were comparable between the two groups (12.5% vs. 17.3%; p = 0.74). No recurrence of GOO symptoms was registered in the EUS-GE group while 11.5% of ES patients had symptoms recurrence, even if not statistically significant ( p = 0.16), after a mean follow-up period of 63.5 days., Conclusion: EUS-GE and ES are both effective and safe for the palliation of GOO in patients already treated by EUS-CDS for DMBO with no difference in the biliary stent dysfunction rate and overall AEs. EUS-GE is associated with less recurrence of GOO symptoms.
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- 2024
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44. Preliminary findings on vitamin D 25-OH levels in urine analysis: implications for clinical practice.
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Piccolini A, Grizzi F, Monari M, Hegazi MAAA, Buffi NM, Casale P, Fasulo V, Moretto S, Cella L, Vota P, Toia G, Mazzieri C, Galli R, Petrillo P, Morelli P, Cantisani A, Bonavolontà C, Scordamaglia C, Cannone I, Veronese N, Villa A, Ossolengo G, Marsili E, and Taverna G
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- Humans, Vitamin D Deficiency complications, Male, Female, Vitamin D blood, Vitamin D analogs & derivatives
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- 2024
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45. The i-EUS consensus on the management of pancreatic fluid collections - Part 1.
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Capurso G, Rizzo GEM, Coluccio C, Crinò SF, Cucchetti A, Facciorusso A, Hassan C, Amato A, Auriemma F, Bertani H, Binda C, Cipolletta F, Forti E, Fugazza A, Lisotti A, Maida M, Sinagra E, Sbrancia M, Spadaccini M, Tacelli M, Vanella G, Anderloni A, Fabbri C, and Tarantino I
- Subjects
- Humans, Consensus, Italy, Pancreatitis therapy, Stents, Ultrasonography, Interventional methods, Ultrasonography, Interventional standards, Consensus Development Conferences as Topic, Drainage methods, Drainage standards, Endosonography methods, Endosonography standards, Pancreatic Pseudocyst therapy, Pancreatic Pseudocyst diagnostic imaging, Pancreatic Pseudocyst surgery
- Abstract
Pancreatic fluid collections (PFCs), including pancreatic pseudocysts (PPs) and walled-off pancreatic necrosis (WON), are common complications of pancreatitis and pancreatic surgery. Historically, the treatment of these conditions has relied on surgical and radiological approaches; however, it has later shifted toward an endoscopy-based approach. With the development of dedicated lumen-apposing metal stents (LAMS), interventional Endoscopic Ultrasound (EUS)-guided procedures have become the standard approach for PFC drainage. However, there is still limited consensus on several aspects of the multidisciplinary management of PFCs. The interventional endoscopy and ultrasound (i-EUS) group is an Italian network of clinicians and scientists with special interest in biliopancreatic interventional endoscopy, especially interventional EUS. This manuscript describes the first part of the results of a consensus conference organized by i-EUS with the aim of providing evidence-based guidance on aspects such as indications for treating PFCs, the timing of intervention, and different technical strategies for managing patients with PFCs., Competing Interests: Conflict of Interest There is no financial support to this study. Chiara Coluccio: Lecturer per steris Cecilia Binda: Lecturer fees for Fujifilm, Steris, Q3 Medical, Boston Scientific. Andrea Lisotti received consultancy from Boston Scientific Giuseppe Vanella: lecture fees from Boston Scientific and travel grants from Euromedical Carlo Fabbri: consultant per Boston scientific, Lecturer per steris e Q3 medical All the other authors have no conflict of interest to declare., (Copyright © 2024. Published by Elsevier Ltd.)
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- 2024
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46. Immune-related [ 18 F]FDG PET findings in patients undergoing checkpoint inhibitors treatment: correlation with clinical adverse events and prognostic implications.
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Santo G, Cucè M, Restuccia A, Del Giudice T, Tassone P, Cicone F, Tagliaferri P, and Cascini GL
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- Humans, Male, Female, Middle Aged, Aged, Retrospective Studies, Prognosis, Adult, Lung Neoplasms drug therapy, Lung Neoplasms diagnostic imaging, Lung Neoplasms mortality, Lung Neoplasms pathology, Lung Neoplasms immunology, Aged, 80 and over, Fluorodeoxyglucose F18, Immune Checkpoint Inhibitors adverse effects, Immune Checkpoint Inhibitors therapeutic use, Melanoma drug therapy, Melanoma diagnostic imaging, Melanoma mortality, Melanoma immunology, Radiopharmaceuticals, Carcinoma, Non-Small-Cell Lung drug therapy, Carcinoma, Non-Small-Cell Lung diagnostic imaging, Carcinoma, Non-Small-Cell Lung mortality, Carcinoma, Non-Small-Cell Lung immunology, Carcinoma, Non-Small-Cell Lung pathology, Positron Emission Tomography Computed Tomography methods
- Abstract
Background: Direct comparisons between [
18 F]FDG PET/CT findings and clinical occurrence of immune-related adverse events (irAEs) based on independent assessments of clinical and imaging features in patients receiving immune checkpoint inhibitors (ICIs) are missing. Our aim was to estimate sites, frequency, and timing of immune-related PET findings during ICIs treatment in patients with melanoma and NSCLC, and to assess their correlation with clinical irAEs. Prognostic implications of immune-related events were also investigated., Methods: Fifty-one patients with melanoma (47%) or NSCLC (53%) undergoing multiple PET examinations during anti-PD1/PDL1 treatment were retrospectively included. Clinical irAEs were graded according to CTCAE v.5.0. Abnormal PET findings suggestive of immune activation were described by two readers blinded to the clinical data. Progression-free survival (PFS) and overall survival (OS) were analyzed with the Kaplan-Meier method in patients stratified according to the presence of irAEs, immune-related PET findings or both., Results: Twenty-one patients showed clinical irAEs only (n = 6), immune-related PET findings only (n = 6), or both (n = 9). In patients whose imaging findings corresponded to clinical irAEs (n = 7), a positive correlation between SUVmax and the severity of the clinical event was observed (rs =0.763, p = 0.046). Clinical irAEs occurred more frequently in patients without macroscopic disease than in metastatic patients (55% vs. 23%, p = 0.039). Patients who developed clinical irAEs had a significantly longer PFS than patients who remained clinically asymptomatic, both in the overall cohort (p = 0.011) and in the subgroup of (n = 35) patients with metastatic disease (p = 0.019). The occurrence of immune-related PET findings significantly stratified PFS in the overall cohort (p = 0.040), and slightly missed statistical significance in patients with metastatic disease (p = 0.08). The best stratification of PFS was achieved when all patients who developed immune-related events, either clinically relevant or detected by PET only, were grouped together both in the overall cohort (p = 0.002) and in patients with metastatic disease (p = 0.004). In the whole sample, OS was longer in patients who developed any immune-related events (p = 0.032)., Conclusion: Patients with melanoma or NSCLC under ICI treatment can develop clinical irAEs, immune-related PET findings, or both. The occurrence of immune-related events has a prognostic impact. Combining clinical information with PET assessment improved outcome stratification., (© 2024. The Author(s).)- Published
- 2024
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47. Development and Management of Avoidant/Restrictive Food Intake Disorder and Food Neophobia in Pediatric Patients with Food Allergy: A Comprehensive Review.
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Nocerino R, Mercuri C, Bosco V, Giordano V, Simeone S, Guillari A, and Rea T
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- Humans, Child, Cognitive Behavioral Therapy methods, Phobic Disorders psychology, Phobic Disorders therapy, Feeding Behavior psychology, Family Therapy methods, Child, Preschool, Food Hypersensitivity psychology, Food Hypersensitivity therapy, Avoidant Restrictive Food Intake Disorder
- Abstract
Avoidant/Restrictive Food Intake Disorder (ARFID) and food neophobia present significant challenges in pediatric healthcare, particularly among children with food allergies (FAs). These eating disorders, characterized by the persistent avoidance or restriction of food, can lead to severe nutritional deficiencies and psychosocial impairments. The presence of FAs further complicates these eating behaviors, as the fear of allergic reactions exacerbates avoidance and restrictive patterns. This comprehensive review synthesizes current knowledge on ARFID and food neophobia, focusing on their definitions, characteristics, and the unique challenges they present in the context of FAs. The review explores the critical role of healthcare professionals, especially nurses, in integrating psychological and clinical care to improve outcomes for affected children. A multidisciplinary approach, including Cognitive Behavioral Therapy (CBT) and Family-Based Therapy (FBT), is emphasized as essential in addressing the complex needs of these patients. The review also highlights the need for standardized treatment protocols and further research on the long-term outcomes of these disorders, aiming to enhance therapeutic strategies and family support systems. Effective management of ARFID and food neophobia in the context of FAs requires a holistic and integrated approach to mitigate the profound impacts on a child's growth, development, and overall well-being.
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- 2024
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48. Recapitulating COVID-19 detection methods: RT-PCR, sniffer dogs and electronic nose.
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Grizzi F, Bax C, Farina FM, Tidu L, Hegazi MAAA, Chiriva-Internati M, Capelli L, Robbiani S, Dellacà R, and Taverna G
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- Animals, Humans, Dogs, Sensitivity and Specificity, Volatile Organic Compounds analysis, COVID-19 Testing methods, Working Dogs, COVID-19 Nucleic Acid Testing methods, COVID-19 diagnosis, COVID-19 virology, SARS-CoV-2 genetics, SARS-CoV-2 isolation & purification, Electronic Nose, Reverse Transcriptase Polymerase Chain Reaction methods
- Abstract
In December 2019, a number of subjects presenting with an unexplained pneumonia-like illness were suspected to have a link to a seafood market in Wuhan, China. Subsequently, this illness was identified as the 2019-novel coronavirus (2019-nCoV) or severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by the World Committee on Virus Classification. Since its initial identification, the virus has rapidly sperad across the globe, posing an extraordinary challenge for the medical community. Currently, the Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) is considered the most reliable method for diagnosing SARS-CoV-2. This procedure involves collecting oro-pharyngeal or nasopharyngeal swabs from individuals. Nevertheless, for the early detection of low viral loads, a more sensitive technique, such as droplet digital PCR (ddPCR), has been suggested. Despite the high effectiveness of RT-PCR, there is increasing interest in utilizing highly trained dogs and electronic noses (eNoses) as alternative methods for screening asymptomatic individuals for SARS-CoV-2. These dogs and eNoses have demonstrated high sensitivity and can detect volatile organic compounds (VOCs), enabling them to distinguish between COVID-19 positive and negative individuals. This manuscript recapitulates the potential, advantages, and limitations of employing trained dogs and eNoses for the screening and control of SARS-CoV-2., Competing Interests: Declaration of competing interest The authors declare that they have no conflict of interest., (Copyright © 2024 Elsevier Inc. All rights reserved.)
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- 2024
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49. Application repetition and electrode-tissue contact result in deeper lesions using a pulsed-field ablation circular variable loop catheter.
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Di Biase L, Marazzato J, Gomez T, Byun E, Zou F, Grupposo V, Mohanty S, La Fazia VM, Ammirati G, Lin A, Garcia DY, Della Rocca D, Al Ahamad A, Schiavone M, Gasperetti A, Freilich M, Serna JC, Forleo G, Liu X, Lakkireddy D, Tondo C, Natale A, and Zhang XD
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- Animals, Swine, Heart Ventricles physiopathology, Heart Ventricles surgery, Models, Animal, Sus scrofa, Time Factors, Catheter Ablation methods, Catheter Ablation instrumentation, Cardiac Catheters, Equipment Design
- Abstract
Aims: Pulsed-field ablation (PFA) is a novel, myocardial-selective, non-thermal ablation modality used to target cardiac arrhythmias. Although prompt electrogram (EGM) signal disappearance is observed immediately after PFA application in the pulmonary veins, whether this finding results in adequate transmural lesions is unknown. The aim of this study is to check whether application repetition and catheter-tissue contact impact lesion formation during PFA., Methods and Results: A circular loop PFA catheter was used to deliver repeated energy applications with various levels of contact force. A benchtop vegetal potato model and a beating heart ventricular myocardial model were utilized to evaluate the impact of application repetition, contact force, and catheter repositioning on contiguity and lesion depth. Lesion development occurred over 18 h in the vegetal model and over 6 h in the porcine model. Lesion formation was found to be dependent on application repetition and contact. In porcine ventricles, single and multiple stacked applications led to a lesion depth of 3.5 ± 0.7 and 4.4 ± 1.3 mm, respectively (P = 0.002). Furthermore, the greater the catheter-tissue contact, the more contiguous and deeper the lesions in the vegetal model (1.0 ± 0.9 mm with no contact vs. 5.4 ± 1.4 mm with 30 g of force; P = 0.0001)., Conclusion: Pulsed-field ablation delivered via a circular catheter showed that both repetition and catheter contact led independently to deeper lesion formation. These findings indicate that endpoints for effective PFA are related more to PFA biophysics than to mere EGM attenuation., Competing Interests: Conflict of interest: L.D.B. is a consultant for Stereotaxis, Biosense Webster, Boston Scientific, Abbott Medical, I-Rhythm, Siemens Medtronic, AtriCure, Biotronik, and Zoll. T.G., E.B., and V.G. are employees of Biosense Webster, Inc., a Johnson & Johnson company. All remaining authors have declared no conflicts of interest., (© The Author(s) 2024. Published by Oxford University Press on behalf of the European Society of Cardiology.)
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- 2024
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50. Posterior Cruciate Buckling Angle Variations Are Associated with Different Patterns of Medial Meniscus Tears in Anterior-Cruciate-Deficient Knees: Results of a Prospective Comparative Magnetic Imaging Resonance Study.
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Cerciello S, Mercurio M, Corona K, Proietti L, Di Vico G, Giordano MC, and Morris BJ
- Abstract
Background: The diagnosis of anterior cruciate ligament (ACL) tear relies on clinical evaluation and magnetic resonance imaging (MRI). Direct and indirect signs of ACL tear have been described with MRI evaluation. Posterior cruciate ligament (PCL) buckling has been described as an indirect radiographic sign of an ACL tear., Purpose: The aim of the present study was to assess the variations in PCL buckling angles in patients with ACL tears and in patients with isolated lesions in the posterior horn of the medial meniscus. In addition, the influence of different patterns of medial meniscus tears in ACL-deficient knees was investigated. Finally, the influences of risk factors such as tibial slope, delay from injury to surgery, absence of medial meniscus tear, degree of Lachman and pivot shift testing were also assessed., Study Design: This was a cohort study., Methods: A total of 154 patients (78 in the group with ACL tear and 76 in the control group) were assessed with MRI and lateral weight-bearing X-ray to assess PCL buckling angle and tibial slope by two independent observers. The presence of a medial meniscus bucket handle or ramp lesion of the medial meniscus was assessed and recorded at the time of surgery., Results: PCL buckling angle measurement was highly reliable, with an ICC of 0.866 and 0.894, respectively, in the study group and the control group for interobserver reliability. The intrarater reliability was found to be high in PCL buckling angle for the study group [ICC = 0.955] and the control group [ICC = 0.943]. The mean angle in patients with ACL tear was 110.7 ± 15.2° and 115.3 ± 16.2° (for the two examiners) and 111.4 ± 12° and 114 ± 14.5° (for the two examiners) in patients with an intact, healthy ACL. An association emerged between bucket handle tears of the medial meniscus ( p = 0.010) and a decreased PCL buckling angle and between ramp lesions of the medial meniscus and increased PCL buckling angle both ( p = 0.024)., Conclusions: Good inter- and intraobserver reliability for the measurement of the PCL buckling angle was observed. Increased PCL buckling angle values were observed in patients with concomitant ACL and bucket handle tears of the medial meniscus, while decreased angle values were observed in those who had ACL tear and ramp lesion of the medial meniscus. No statistically significant difference in the PCL buckling angle emerged between patients with ACL tears and those who had a healthy, intact ACL.
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- 2024
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