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445 results on '"Martti Färkkilä"'

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1. Surrogate markers of bile duct disease progression in primary sclerosing cholangitis – A prospective study with repeated ERCP examinations

2. TWINGEN: protocol for an observational clinical biobank recall and biomarker cohort study to identify Finnish individuals with high risk of Alzheimer’s disease

3. Maternal liver-related symptoms during pregnancy in primary sclerosing cholangitis

4. Waist-hip ratio is superior to BMI in predicting liver-related outcomes and synergizes with harmful alcohol use

5. PRIMIS: design of a pivotal, randomized, phase 3 study evaluating the safety and efficacy of the nonsteroidal farnesoid X receptor agonist cilofexor in noncirrhotic patients with primary sclerosing cholangitis

6. Enhanced liver Fibrosis® test predicts liver-related outcomes in the general population

7. Association between arterial hypertension and liver outcomes using polygenic risk scores: a population-based study

8. Biliary hCGβ Is a Potential Novel Marker for Prediction of Biliary Neoplasia in Primary Sclerosing Cholangitis Patients

9. Recontacting biobank participants to collect lifestyle, behavioural and cognitive information via online questionnaires: lessons from a pilot study within FinnGen

10. A Dynamic Aspartate‐to‐Alanine Aminotransferase Ratio Provides Valid Predictions of Incident Severe Liver Disease

11. Chronic cholestasis detection by a novel tool: automated analysis of cytokeratin 7-stained liver specimens

12. PNPLA3 allele frequency has no impact on biliary bile acid composition or disease course in patients with primary sclerosing cholangitis.

13. Quantitative bile and serum proteomics for the screening and differential diagnosis of primary sclerosing cholangitis.

14. Serum lipopolysaccharides predict advanced liver disease in the general population

15. Sleep apnoea is a risk factor for severe COVID-19

16. Piloting gender-oriented colorectal cancer screening with a faecal immunochemical test: population-based registry study from Finland

17. Tubular cell damage may be the earliest sign of renal extrahepatic manifestation caused by Hepatitis C.

19. A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis

20. Unexpectedly High Prevalence of Common Variable Immunodeficiency in Finland

21. Bile microbiota in primary sclerosing cholangitis: Impact on disease progression and development of biliary dysplasia.

22. Randomized Trial Evaluating the Impact of Ribavirin Mono-Therapy and Double Dosing on Viral Kinetics, Ribavirin Pharmacokinetics and Anemia in Hepatitis C Virus Genotype 1 Infection.

23. A novel fibrosis index comprising a non-cholesterol sterol accurately predicts HCV-related liver cirrhosis.

24. Dendritic cells from Crohn's disease patients show aberrant STAT1 and STAT3 signaling.

25. Erratum: A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis

26. Impact of obesity on the bioavailability of peginterferon-α2a and ribavirin and treatment outcome for chronic hepatitis C genotype 2 or 3.

27. Impact of IL28B-related single nucleotide polymorphisms on liver histopathology in chronic hepatitis C genotype 2 and 3.

28. A structural variation reference for medical and population genetics.

29. Abdominal obesity and alcohol use modify the impact of genetic risk for incident advanced liver disease in the general population

30. Automated image analysis of keratin 7 staining can predict disease outcome in primary sclerosing cholangitis

31. Development and validation of a model to predict incident chronic liver disease in the general population: The CLivD score

32. Risk of Midlife Stroke After Adverse Pregnancy Outcomes: The FinnGen Study

33. Novel histological scoring for predicting disease outcome in primary sclerosing cholangitis

34. New insights into the genetic etiology of Alzheimer's disease and related dementias

36. Comparison of various strategies to define the optimal target population for liver fibrosis screening : A population-based cohort study

37. Presence of interferon-λ 4, male gender, absent/mild steatosis and low viral load augment antibody levels to hepatitis C virus

38. Laryngeal and Pharyngeal Squamous Cell Carcinoma After Antireflux Surgery in the 5 Nordic Countries

42. FinnGen: Unique genetic insights from combining isolated population and national health register data

44. Incidence and Mortality in Upper Gastrointestinal Cancer After Negative Endoscopy for Gastroesophageal Reflux Disease

45. Early and accurate detection of cholangiocarcinoma in patients with primary sclerosing cholangitis by methylation markers in bile

46. Can dysplasia surveillance be better targeted in ulcerative colitis by using faecal calprotectin?

47. Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes

48. Diclofenac does not reduce the risk of acute pancreatitis in patients with primary sclerosing cholangitis after endoscopic retrograde cholangiography

49. Health-related quality of life before and after liver transplantation in patients with primary sclerosing cholangitis

50. Drinking and Obesity: Alcoholic Liver Disease/Nonalcoholic Fatty Liver Disease Interactions

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