27 results on '"Martinez-Vila, Clara"'
Search Results
2. SARS-CoV-2 infection in patients with melanoma: results of the Spanish Melanoma Group registry
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Gonzalez-Cao, Maria, Puertolas, Teresa, Martinez-Vila, Clara, Carrera, Cristina, Maldonado Seral, Cayetana, Rodríguez-Jiménez, Pedro, Sequero, Silvia, Cerezuela-Fuentes, Pablo, Feltes Ochoa, Rosa, Muñoz, Eva, Antoñanzas Basa, Mónica, Martín-Liberal, Juan, Soria, Ainara, Francisco Rodriguez Moreno, Juan, Marquez-Rodas, Ivan, Lopez Criado, Pilar, Luis Manzano, José, Lopez-Castro, Rafael, Ayala de Miguel, Pablo, Villalobos, Laura, Martin Algarra, Salvador, Gonzalez-Barrallo, Ines, Boada, Aram, García Castaño, Almudena, Puig, Susana, Crespo, Guillermo, Luna Fra, Pablo, Aguayo Zamora, Cristina, Feito Rodríguez, Marta, Valles, Lara, Drozdowskyj, Ana, Gardeazabal, Jesús, Antonio Fernandez-Morales, Luis, Rodrigo, Alberto, Cruz, Raquel, Yelamos, Oriol, Rubio, Belen, Mujica, Karmele, Provencio, Mariano, and Berrocal, Alfonso
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- 2023
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3. Natural immunity to SARS-CoV-2 and breakthrough infections in vaccinated and unvaccinated patients with cancer
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Cortellini, Alessio, Aguilar-Company, Juan, Salazar, Ramon, Bower, Mark, Sita-Lumsden, Ailsa, Plaja, Andrea, Lee, Alvin J. X., Bertuzzi, Alexia, Tondini, Carlo, Diamantis, Nikolaos, Martinez-Vila, Clara, Prat, Aleix, Apthorp, Eleanor, Gennari, Alessandra, and Pinato, David J.
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- 2022
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4. SARS-CoV-2 omicron (B.1.1.529)-related COVID-19 sequelae in vaccinated and unvaccinated patients with cancer: results from the OnCovid registry
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Evans, Joanne S, Swallow, Judith, Hanbury, Georgina, Chung, Chris, Patel, Meera, Dettorre, Gino, Belessiotis, Katherine, Saorise, Dolly, Jones, Eleanor, Apthorp, Eleanor, Moss, Charlotte, Russell, Beth, Townsend, Sarah, Jackson, Amanda, Loizidou, Angela, Piccart, Martine, Pommeret, Fanny, Colomba-Blameble, Emeline, Prat, Aleix, Cruz, Claudia A, Reyes, Roxana, Segui, Elia, Marco-Hernández, Javier, Viladot, Margarita, Harbeck, Nadia, Wuerstlein, Rachel, Henze, Franziska, Mahner, Sven, Felip, Eudald, Scotti, Lorenza, Marrari, Andrea, Grosso, Federica, Fusco, Vittorio, Delfanti, Sara, Rossi, Maura, Zambelli, Alberto, Tondini, Carlo, Chiudinelli, Lorenzo, Franchi, Michela, Libertini, Michela, Provenzano, Salvatore, Generali, Daniele, Grisanti, Salvatore, Baggi, Alice, Tovazzi, Valeria, Ficorella, Corrado, Porzio, Giampiero, Saponara, Maristella, Filetti, Marco, Tucci, Marco, Berardi, Rossana, Cantini, Luca, Paoloni, Francesco, Guida, Annalisa, Bracarda, Sergio, Iglesias, Maria, Sanchez de Torre, Ana, Tagliamento, Marco, Cortellini, Alessio, Tabernero, Josep, Mukherjee, Uma, Salazar, Ramon, Sureda, Anna, Maluquer, Clara, Ferrante, Daniela, Bower, Mark, Sharkey, Rachel, Mirallas, Oriol, Plaja, Andrea, Cucurull, Marc, Mesia, Ricard, Dalla Pria, Alessia, Newsom-Davis, Thomas, Van Hemelrijck, Mieke, Sita-Lumsden, Ailsa, Vincenzi, Bruno, Di Fazio, Giuseppina Rita, Tonini, Giuseppe, Pantano, Francesco, Bertuzzi, Alexia, Rossi, Sabrina, Brunet, Joan, Lambertini, Matteo, Pedrazzoli, Paolo, Biello, Federica, D'Avanzo, Francesca, Lee, Alvin J X, Shawe-Taylor, Marianne, Rogers, Lucy, Murphy, Cian, Cooper, Lee, Andaleeb, Ramis, Khalique, Saira, Bawany, Samira, Ahmed, Sarah, Carmona-García, M Carmen, Fort-Culillas, Roser, Liñan, Raquel, Zoratto, Federica, Rizzo, Gianpiero, Perachino, Marta, Doonga, Kris, Gaidano, Gianluca, Bruna, Riccardo, Patriarca, Andrea, Martinez-Vila, Clara, Pérez Criado, Ignacio, Giusti, Raffaele, Mazzoni, Francesca, Antonuzzo, Lorenzo, Santoro, Armando, Parisi, Alessandro, Queirolo, Paola, Aujayeb, Avinash, Rimassa, Lorenza, Diamantis, Nikolaos, Bertulli, Rossella, Fulgenzi, Claudia A M, D'Alessio, Antonio, Ruiz-Camps, Isabel, Saoudi-Gonzalez, Nadia, Garcia Illescas, David, Medina, Irene, Fox, Laura, Gennari, Alessandra, Aguilar-Company, Juan, and Pinato, David J
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- 2023
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5. Outcomes of the SARS-CoV-2 omicron (B.1.1.529) variant outbreak among vaccinated and unvaccinated patients with cancer in Europe: results from the retrospective, multicentre, OnCovid registry study
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Evans, Joanne S, Swallow, Judith, Chung, Chris, Patel, Meera, Dettorre, Gino, Ottaviani, Diego, Chowdhury, Amani, Merry, Eve, Chopra, Neha, Lee, Alvin JX, Sng, Christopher CT, Yu, Tamara, Shawe-Taylor, Marianne, Bain, Hamish DC, Wong, Yien Ning Sophia, Galazi, Myria, Benafif, Sarah, Dileo, Palma, Earnshaw, Irina, Patel, Grisma, Wu, Anjui, Soosaipillai, Gehan, Cooper, Lee, Andaleeb, Ramis, Dolly, Saoirse, Apthorp, Eleanor, Srikandarajah, Krishnie, Jones, Eleanor, Van Hemelrijck, Mieke, Moss, Charlotte, Russell, Beth, Chester, John, Loizidou, Angela, Piccart, Martine, Cruz, Claudia A, Reyes, Roxana, Segui, Elia, Marco-Hernández, Javier, Viladot, Margarita, Eremiev, Simeon, Fort-Culillas, Roser, Garcia, Isabel, Liñan, Raquel, Roqué Lloveras, Ariadna, Harbeck, Nadia, Wuerstlein, Rachel, Henze, Franziska, Mahner, Sven, Felip, Eudald, Pous, Anna, D'Avanzo, Francesca, Scotti, Lorenza, Krengli, Marco, Marrari, Andrea, Delfanti, Sara, Maconi, Antonio, Betti, Marta, Tonini, Giuseppe, Di Fazio, Giuseppina Rita, Tondini, Carlo, Chiudinelli, Lorenzo, Franchi, Michela, Libertini, Michela, Bertulli, Rossella, Baggi, Alice, Tovazzi, Valeria, Ficorella, Corrado, Porzio, Giampiero, Saponara, Maristella, Filetti, Marco, Zoratto, Federica, Paoloni, Francesco, Berardi, Rossana, Guida, Annalisa, Bracarda, Sergio, Iglesias, Maria, Sanchez de Torre, Ana, Tagliamento, Marco, Colomba, Emeline, Pommeret, Fanny, Pinato, David J, Aguilar-Company, Juan, Ferrante, Daniela, Hanbury, Georgina, Bower, Mark, Salazar, Ramon, Mirallas, Oriol, Sureda, Anna, Plaja, Andrea, Cucurull, Marc, Mesia, Ricard, Townsend, Sarah, Jackson, Amanda, Dalla Pria, Alessia, Newsom-Davis, Thomas, Handford, Jasmine, Sita-Lumsden, Ailsa, Vincenzi, Bruno, Bertuzzi, Alexia, Brunet, Joan, Lambertini, Matteo, Maluquer, Clara, Pedrazzoli, Paolo, Biello, Federica, Sinclair, Alasdair, Bawany, Samira, Khalique, Saira, Rossi, Sabrina, Rogers, Lucy, Murphy, Cian, Belessiotis, Katherine, Carmona-García, M Carmen, Sharkey, Rachel, García-Illescas, David, Rizzo, Gianpiero, Perachino, Marta, Saoudi-Gonzalez, Nadia, Doonga, Kris, Fox, Laura, Roldán, Elisa, Gaidano, Gianluca, Ruiz-Camps, Isabel, Bruna, Riccardo, Patriarca, Andrea, Martinez-Vila, Clara, Cantini, Luca, Zambelli, Alberto, Giusti, Raffaele, Mazzoni, Francesca, Caliman, Enrico, Santoro, Armando, Grosso, Federica, Parisi, Alessandro, Queirolo, Paola, Aujayeb, Avinash, Rimassa, Lorenza, Prat, Aleix, Tucci, Marco, Grisanti, Salvatore, Mukherjee, Uma, Diamantis, Nikolaos, Fusco, Vittorio, Generali, Daniele, Provenzano, Salvatore, Gennari, Alessandra, Tabernero, Josep, and Cortellini, Alessio
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- 2022
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6. Prevalence and impact of COVID-19 sequelae on treatment and survival of patients with cancer who recovered from SARS-CoV-2 infection: evidence from the OnCovid retrospective, multicentre registry study
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Swallow, Judith, Chung, Chris, Dettorre, Gino, Chopra, Neha, Lee, Alvin JX, Sng, Christopher CT, Wong, Yien Ning Sophia, Galazi, Myria, Benafif, Sarah, Dileo, Palma, Patel, Grisma, Wu, Anjui, Sinclair, Alasdair, Soosaipillai, Gehan, Jones, Eleanor, Diamantis, Nikolaos, Mukherjee, Uma, Jackson, Amanda, Piccart, Martine, Pommeret, Fanny, Colomba, Johann, Colomba-Blameble, Emeline, Prat, Aleix, Cruz, Claudia A, Reyes, Roxana, Segui, Elia, Marco-Hernández, Javier, Tabernero, Josep, Aguilar-Company, Juan, Ruiz-Camps, Isabel, Fox, Laura, Garcia Illescas, David, Mirallas, Oriol, Roldán, Elisa, Carbó, Anna, Garcia, Isabel, Wuerstlein, Rachel, Mesia, Ricard, Maluquer, Clara, D'Avanzo, Francesca, Tonini, Giuseppe, Provenzano, Salvatore, Tovazzi, Valeria, Ficorella, Corrado, Queirolo, Paola, Giusti, Raffaele, Mazzoni, Francesca, Zoratto, Federica, Tucci, Marco, Berardi, Rossana, Guida, Annalisa, Bracarda, Sergio, Iglesias, Maria, Pinato, David J, Bower, Mark, Scotti, Lorenza, Patel, Meera, Colomba, Emeline, Dolly, Saoirse, Loizidou, Angela, Chester, John, Zambelli, Alberto, Dalla Pria, Alessia, Ottaviani, Diego, Chowdhury, Amani, Merry, Eve, Salazar, Ramon, Bertuzzi, Alexia, Brunet, Joan, Lambertini, Matteo, Tagliamento, Marco, Pous, Anna, Sita-Lumsden, Ailsa, Srikandarajah, Krishnie, Seguí, Elia, Generali, Daniele, Grisanti, Salvatore, Pedrazzoli, Paolo, Rizzo, Gianpiero, Libertini, Michela, Moss, Charlotte, Evans, Joanne S, Russell, Beth, Harbeck, Nadia, Vincenzi, Bruno, Biello, Federica, Bertulli, Rossella, Liñan, Raquel, Rossi, Sabrina, Carmona-García, Maria Carmen, Tondini, Carlo, Baggi, Alice, Fotia, Vittoria, Parisi, Alessandro, Porzio, Giampero, Saponara, Maristella, Cruz, Claudia Andrea, García-Illescas, David, Felip, Eudald, Roqué Lloveras, Ariadna, Sharkey, Rachel, Earnshaw, Irina, Ferrante, Daniela, Gaidano, Gianluca, Patriarca, Andrea, Bruna, Riccardo, Sureda, Anna, Martinez-Vila, Clara, Sanchez de Torre, Ana, Cantini, Luca, Filetti, Marco, Rimassa, Lorenza, Chiudinelli, Lorenzo, Franchi, Michela, Krengli, Marco, Santoro, Armando, Van Hemelrijck, Mieke, Newsom-Davis, Thomas, Gennari, Alessandra, and Cortellini, Alessio
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- 2021
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7. Validity of a rapid diagnostic programme for head and neck cancer
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Rosell Ferrer, Rosa, Aguilà Artal, Anton, Escamilla Carpintero, Yolanda, Cardesin Revilla, Alda, Campos Motamayor, Mariana, Díaz Argüello, Juan José, Martínez Arias, Angels, and Martínez Vila, Clara
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- 2021
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8. Validez de un programa de diagnóstico rápido del cáncer de cabeza y cuello
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Rosell Ferrer, Rosa, Aguilà Artal, Anton, Escamilla Carpintero, Yolanda, Cardesin Revilla, Alda, Campos Motamayor, Mariana, Díaz Argüello, Juan José, Martínez Arias, Angels, and Martínez Vila, Clara
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- 2021
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9. Anti-angiogenic therapy for ovarian cancer
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García García, Yolanda, Marín Alcalá, Maria, and Martínez Vila, Clara
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- 2020
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10. Pandemic Phase-Adjusted Analysis of COVID-19 Outcomes Reveals Reduced Intrinsic Vulnerability and Substantial Vaccine Protection From Severe Acute Respiratory Syndrome Coronavirus 2 in Patients With Breast Cancer
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Tagliamento, Marco, primary, Gennari, Alessandra, additional, Lambertini, Matteo, additional, Salazar, Ramon, additional, Harbeck, Nadia, additional, Del Mastro, Lucia, additional, Aguilar-Company, Juan, additional, Bower, Mark, additional, Sharkey, Rachel, additional, Dalla Pria, Alessia, additional, Plaja, Andrea, additional, Jackson, Amanda, additional, Handford, Jasmine, additional, Sita-Lumsden, Ailsa, additional, Martinez-Vila, Clara, additional, Matas, Marta, additional, Miguel Rodriguez, Ana, additional, Vincenzi, Bruno, additional, Tonini, Giuseppe, additional, Bertuzzi, Alexia, additional, Brunet, Joan, additional, Pedrazzoli, Paolo, additional, D'Avanzo, Francesca, additional, Biello, Federica, additional, Sinclair, Alasdair, additional, Lee, Alvin J.X., additional, Rossi, Sabrina, additional, Rizzo, Gianpiero, additional, Mirallas, Oriol, additional, Pimentel, Isabel, additional, Iglesias, Maria, additional, Sanchez de Torre, Ana, additional, Guida, Annalisa, additional, Berardi, Rossana, additional, Zambelli, Alberto, additional, Tondini, Carlo, additional, Filetti, Marco, additional, Mazzoni, Francesca, additional, Mukherjee, Uma, additional, Diamantis, Nikolaos, additional, Parisi, Alessandro, additional, Aujayeb, Avinash, additional, Prat, Aleix, additional, Libertini, Michela, additional, Grisanti, Salvatore, additional, Rossi, Maura, additional, Zoratto, Federica, additional, Generali, Daniele, additional, Saura, Cristina, additional, Lyman, Gary H., additional, Kuderer, Nicole M., additional, Pinato, David J., additional, and Cortellini, Alessio, additional
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- 2023
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11. Ki67 expression as a predictor of chemotherapy outcome in low-grade serous ovarian cancer
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Grabowski, Jacek P, Martinez Vila, Clara, Richter, Rolf, Taube, Eliane, Plett, Helmut, Braicu, Elena, and Sehouli, Jalid
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- 2020
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12. SARS-CoV-2 omicron (B.1.1.529)-related COVID-19 sequelae in vaccinated and unvaccinated patients with cancer: results from the OnCovid registry
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Cortellini, Alessio, primary, Tabernero, Josep, additional, Mukherjee, Uma, additional, Salazar, Ramon, additional, Sureda, Anna, additional, Maluquer, Clara, additional, Ferrante, Daniela, additional, Bower, Mark, additional, Sharkey, Rachel, additional, Mirallas, Oriol, additional, Plaja, Andrea, additional, Cucurull, Marc, additional, Mesia, Ricard, additional, Dalla Pria, Alessia, additional, Newsom-Davis, Thomas, additional, Van Hemelrijck, Mieke, additional, Sita-Lumsden, Ailsa, additional, Apthorp, Eleanor, additional, Vincenzi, Bruno, additional, Di Fazio, Giuseppina Rita, additional, Tonini, Giuseppe, additional, Pantano, Francesco, additional, Bertuzzi, Alexia, additional, Rossi, Sabrina, additional, Brunet, Joan, additional, Lambertini, Matteo, additional, Pedrazzoli, Paolo, additional, Biello, Federica, additional, D'Avanzo, Francesca, additional, Lee, Alvin J X, additional, Shawe-Taylor, Marianne, additional, Rogers, Lucy, additional, Murphy, Cian, additional, Cooper, Lee, additional, Andaleeb, Ramis, additional, Khalique, Saira, additional, Bawany, Samira, additional, Ahmed, Sarah, additional, Carmona-García, M Carmen, additional, Fort-Culillas, Roser, additional, Liñan, Raquel, additional, Zoratto, Federica, additional, Rizzo, Gianpiero, additional, Perachino, Marta, additional, Doonga, Kris, additional, Gaidano, Gianluca, additional, Bruna, Riccardo, additional, Patriarca, Andrea, additional, Martinez-Vila, Clara, additional, Pérez Criado, Ignacio, additional, Giusti, Raffaele, additional, Mazzoni, Francesca, additional, Antonuzzo, Lorenzo, additional, Santoro, Armando, additional, Parisi, Alessandro, additional, Queirolo, Paola, additional, Aujayeb, Avinash, additional, Rimassa, Lorenza, additional, Diamantis, Nikolaos, additional, Bertulli, Rossella, additional, Fulgenzi, Claudia A M, additional, D'Alessio, Antonio, additional, Ruiz-Camps, Isabel, additional, Saoudi-Gonzalez, Nadia, additional, Garcia Illescas, David, additional, Medina, Irene, additional, Fox, Laura, additional, Gennari, Alessandra, additional, Aguilar-Company, Juan, additional, Pinato, David J, additional, Evans, Joanne S, additional, Swallow, Judith, additional, Hanbury, Georgina, additional, Chung, Chris, additional, Patel, Meera, additional, Dettorre, Gino, additional, Belessiotis, Katherine, additional, Saorise, Dolly, additional, Jones, Eleanor, additional, Moss, Charlotte, additional, Russell, Beth, additional, Townsend, Sarah, additional, Jackson, Amanda, additional, Loizidou, Angela, additional, Piccart, Martine, additional, Pommeret, Fanny, additional, Colomba-Blameble, Emeline, additional, Prat, Aleix, additional, Cruz, Claudia A, additional, Reyes, Roxana, additional, Segui, Elia, additional, Marco-Hernández, Javier, additional, Viladot, Margarita, additional, Harbeck, Nadia, additional, Wuerstlein, Rachel, additional, Henze, Franziska, additional, Mahner, Sven, additional, Felip, Eudald, additional, Scotti, Lorenza, additional, Marrari, Andrea, additional, Grosso, Federica, additional, Fusco, Vittorio, additional, Delfanti, Sara, additional, Rossi, Maura, additional, Zambelli, Alberto, additional, Tondini, Carlo, additional, Chiudinelli, Lorenzo, additional, Franchi, Michela, additional, Libertini, Michela, additional, Provenzano, Salvatore, additional, Generali, Daniele, additional, Grisanti, Salvatore, additional, Baggi, Alice, additional, Tovazzi, Valeria, additional, Ficorella, Corrado, additional, Porzio, Giampiero, additional, Saponara, Maristella, additional, Filetti, Marco, additional, Tucci, Marco, additional, Berardi, Rossana, additional, Cantini, Luca, additional, Paoloni, Francesco, additional, Guida, Annalisa, additional, Bracarda, Sergio, additional, Iglesias, Maria, additional, Sanchez de Torre, Ana, additional, and Tagliamento, Marco, additional
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- 2023
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13. Vaccination against SARS-CoV-2 protects from morbidity, mortality and sequelae from COVID19 in patients with cancer
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Pinato, David J., primary, Ferrante, Daniela, additional, Aguilar-Company, Juan, additional, Bower, Mark, additional, Salazar, Ramon, additional, Mirallas, Oriol, additional, Sureda, Anna, additional, Bertuzzi, Alexia, additional, Brunet, Joan, additional, Lambertini, Matteo, additional, Maluquer, Clara, additional, Pedrazzoli, Paolo, additional, Biello, Federica, additional, Lee, Alvin J.X., additional, Sng, Christopher C.T., additional, Liñan, Raquel, additional, Rossi, Sabrina, additional, Carmona-García, M.Carmen, additional, Sharkey, Rachel, additional, Eremiev, Simeon, additional, Rizzo, Gianpiero, additional, Bain, Hamish DC., additional, Yu, Tamara, additional, Cruz, Claudia A., additional, Perachino, Marta, additional, Saoudi-Gonzalez, Nadia, additional, Fort-Culillas, Roser, additional, Doonga, Kris, additional, Fox, Laura, additional, Roldán, Elisa, additional, Zoratto, Federica, additional, Gaidano, Gianluca, additional, Ruiz-Camps, Isabel, additional, Bruna, Riccardo, additional, Patriarca, Andrea, additional, Shawe-Taylor, Marianne, additional, Fusco, Vittorio, additional, Martinez-Vila, Clara, additional, Berardi, Rossana, additional, Filetti, Marco, additional, Mazzoni, Francesca, additional, Santoro, Armando, additional, Delfanti, Sara, additional, Parisi, Alessandro, additional, Queirolo, Paola, additional, Aujayeb, Avinash, additional, Rimassa, Lorenza, additional, Prat, Aleix, additional, Tabernero, Josep, additional, Gennari, Alessandra, additional, Cortellini, Alessio, additional, Pinato, David J., additional, Evans, Joanne S., additional, Swallow, Judith, additional, Hanbury, Georgina, additional, Chung, Chris, additional, Patel, Meera, additional, Dettorre, Gino, additional, Ottaviani, Diego, additional, Chowdhury, Amani, additional, Lee, Alvin JX., additional, Sng, Christopher CT., additional, Sinclair, Alasdair, additional, Cooper, Lee, additional, Rogers, Lucy, additional, Belessiotis, Katherine, additional, Murphy, Cian, additional, Bawany, Samira, additional, Khalique, Saira, additional, Andaleeb, Ramis, additional, Dalla Pria, Alessia, additional, Newsom-Davis, Thomas, additional, Dolly, Saorise, additional, Sita-Lumsde, Ailsa, additional, Apthorp, Eleanor, additional, Jones, Eleanor, additional, Van Hemelrijck, Mieke, additional, Moss, Charlotte, additional, Russell, Beth, additional, Diamantis, Nikolaos, additional, Mukherjee, Uma, additional, Townsend, Sarah, additional, Jackson, Amanda, additional, Loizidou, Angela, additional, Piccart, Martine, additional, Reyes, Roxana, additional, Segui, Elia, additional, Marco-Hernández, Javier, additional, Viladot, Margarita, additional, Garcia Illescas, David, additional, Saoudi, Nadia, additional, Carmona Garcia, MCarmen, additional, Fort-Culillas, Robert, additional, Harbeck, Nadia, additional, Wuerstlein, Rachel, additional, Henze, Franziska, additional, Mahner, Sven, additional, Mesia, Ricard, additional, Felip, Eudald, additional, Plaja, Andrea, additional, Cucurull, Marc, additional, D’Avanzo, Francesca, additional, Scotti, Lorenza, additional, Krengly, Marco, additional, Marrari, Andrea, additional, Grosso, Federica, additional, Maconi, Antonio, additional, Betti, Marta, additional, Vincenzi, Bruno, additional, Tonini, Giuseppe, additional, Zambelli, Alberto, additional, Tondini, Carlo, additional, Fotia, Vittoria, additional, Chiudinelli, Lorenzo, additional, Franchi, Michela, additional, Libertini, Michela, additional, Bertulli, Rossella, additional, Provenzano, Salvatore, additional, Generali, Daniele, additional, Grisanti, Salvatore, additional, Baggi, Alice, additional, Tovazzi, Valeria, additional, Ficorella, Corrado, additional, Porzio, Giampiero, additional, Saponara, Maristella, additional, Giusti, Raffaele, additional, Tucci, Marco, additional, Cantini, Luca, additional, Paoloni, Francesco, additional, Guida, Annalisa, additional, Bracarda, Sergio, additional, Iglesias, Maria, additional, Sanchez de Torre, Ana, additional, Pommeret, Fanny, additional, and Colomba, Emeline, additional
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- 2022
- Full Text
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14. Persistence of long-term COVID-19 sequelae in patients with cancer: An analysis from the OnCovid registry
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Cortellini, Alessio, primary, Salazar, Ramon, additional, Gennari, Alessandra, additional, Aguilar-Company, Juan, additional, Bower, Mark, additional, Bertuzzi, Alexia, additional, Brunet, Joan, additional, Lambertini, Matteo, additional, Maluquer, Clara, additional, Pedrazzoli, Paolo, additional, Lee, Alvin JX., additional, Carmona-García, MCarmen, additional, Newsom-Davis, Thomas, additional, Van Hemelrijck, Mieke, additional, Plaja, Andrea, additional, Zambelli, Alberto, additional, Tondini, Carlo, additional, Generali, Daniele, additional, Bertulli, Rossella, additional, Diamantis, Nikolaos, additional, Mukherjee, Uma, additional, Rizzo, Gianpiero, additional, Yu, Tamara, additional, Zoratto, Federica, additional, Bruna, Riccardo, additional, Sureda, Anna, additional, Martinez-Vila, Clara, additional, Cantini, Luca, additional, Mazzoni, Francesca, additional, Grosso, Federica, additional, Parisi, Alessandro, additional, Saponara, Maristella, additional, Prat, Aleix, additional, and Pinato, David J., additional
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- 2022
- Full Text
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15. Outcomes of the SARS-CoV-2 omicron (B.1.1.529) variant outbreak among vaccinated and unvaccinated patients with cancer in Europe: results from the retrospective, multicentre, OnCovid registry study
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Pinato, David J, primary, Aguilar-Company, Juan, additional, Ferrante, Daniela, additional, Hanbury, Georgina, additional, Bower, Mark, additional, Salazar, Ramon, additional, Mirallas, Oriol, additional, Sureda, Anna, additional, Plaja, Andrea, additional, Cucurull, Marc, additional, Mesia, Ricard, additional, Townsend, Sarah, additional, Jackson, Amanda, additional, Dalla Pria, Alessia, additional, Newsom-Davis, Thomas, additional, Handford, Jasmine, additional, Sita-Lumsden, Ailsa, additional, Apthorp, Eleanor, additional, Vincenzi, Bruno, additional, Bertuzzi, Alexia, additional, Brunet, Joan, additional, Lambertini, Matteo, additional, Maluquer, Clara, additional, Pedrazzoli, Paolo, additional, Biello, Federica, additional, Sinclair, Alasdair, additional, Bawany, Samira, additional, Khalique, Saira, additional, Rossi, Sabrina, additional, Rogers, Lucy, additional, Murphy, Cian, additional, Belessiotis, Katherine, additional, Carmona-García, M Carmen, additional, Sharkey, Rachel, additional, García-Illescas, David, additional, Rizzo, Gianpiero, additional, Perachino, Marta, additional, Saoudi-Gonzalez, Nadia, additional, Doonga, Kris, additional, Fox, Laura, additional, Roldán, Elisa, additional, Gaidano, Gianluca, additional, Ruiz-Camps, Isabel, additional, Bruna, Riccardo, additional, Patriarca, Andrea, additional, Martinez-Vila, Clara, additional, Cantini, Luca, additional, Zambelli, Alberto, additional, Giusti, Raffaele, additional, Mazzoni, Francesca, additional, Caliman, Enrico, additional, Santoro, Armando, additional, Grosso, Federica, additional, Parisi, Alessandro, additional, Queirolo, Paola, additional, Aujayeb, Avinash, additional, Rimassa, Lorenza, additional, Prat, Aleix, additional, Tucci, Marco, additional, Libertini, Michela, additional, Grisanti, Salvatore, additional, Mukherjee, Uma, additional, Diamantis, Nikolaos, additional, Fusco, Vittorio, additional, Generali, Daniele, additional, Provenzano, Salvatore, additional, Gennari, Alessandra, additional, Tabernero, Josep, additional, Cortellini, Alessio, additional, Evans, Joanne S, additional, Swallow, Judith, additional, Chung, Chris, additional, Patel, Meera, additional, Dettorre, Gino, additional, Ottaviani, Diego, additional, Chowdhury, Amani, additional, Merry, Eve, additional, Chopra, Neha, additional, Lee, Alvin JX, additional, Sng, Christopher CT, additional, Yu, Tamara, additional, Shawe-Taylor, Marianne, additional, Bain, Hamish DC, additional, Wong, Yien Ning Sophia, additional, Galazi, Myria, additional, Benafif, Sarah, additional, Dileo, Palma, additional, Earnshaw, Irina, additional, Patel, Grisma, additional, Wu, Anjui, additional, Soosaipillai, Gehan, additional, Cooper, Lee, additional, Andaleeb, Ramis, additional, Dolly, Saoirse, additional, Srikandarajah, Krishnie, additional, Jones, Eleanor, additional, Van Hemelrijck, Mieke, additional, Moss, Charlotte, additional, Russell, Beth, additional, Chester, John, additional, Loizidou, Angela, additional, Piccart, Martine, additional, Cruz, Claudia A, additional, Reyes, Roxana, additional, Segui, Elia, additional, Marco-Hernández, Javier, additional, Viladot, Margarita, additional, Eremiev, Simeon, additional, Fort-Culillas, Roser, additional, Garcia, Isabel, additional, Liñan, Raquel, additional, Roqué Lloveras, Ariadna, additional, Harbeck, Nadia, additional, Wuerstlein, Rachel, additional, Henze, Franziska, additional, Mahner, Sven, additional, Felip, Eudald, additional, Pous, Anna, additional, D'Avanzo, Francesca, additional, Scotti, Lorenza, additional, Krengli, Marco, additional, Marrari, Andrea, additional, Delfanti, Sara, additional, Maconi, Antonio, additional, Betti, Marta, additional, Tonini, Giuseppe, additional, Di Fazio, Giuseppina Rita, additional, Tondini, Carlo, additional, Chiudinelli, Lorenzo, additional, Franchi, Michela, additional, Bertulli, Rossella, additional, Baggi, Alice, additional, Tovazzi, Valeria, additional, Ficorella, Corrado, additional, Porzio, Giampiero, additional, Saponara, Maristella, additional, Filetti, Marco, additional, Zoratto, Federica, additional, Paoloni, Francesco, additional, Berardi, Rossana, additional, Guida, Annalisa, additional, Bracarda, Sergio, additional, Iglesias, Maria, additional, Sanchez de Torre, Ana, additional, Tagliamento, Marco, additional, Colomba, Emeline, additional, and Pommeret, Fanny, additional
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- 2022
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16. Persistence of long-term COVID-19 sequelae in patients with cancer:An analysis from the OnCovid registry
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Cortellini, Alessio, Salazar, Ramon, Gennari, Alessandra, Aguilar-Company, Juan, Bower, Mark, Bertuzzi, Alexia, Brunet, Joan, Lambertini, Matteo, Maluquer, Clara, Pedrazzoli, Paolo, Lee, Alvin JX, Carmona-García, MCarmen C., Newsom-Davis, Thomas, Van Hemelrijck, Mieke, Plaja, Andrea, Zambelli, Alberto, Tondini, Carlo, Generali, Daniele, Bertulli, Rossella, Diamantis, Nikolaos, Mukherjee, Uma, Rizzo, Gianpiero, Yu, Tamara, Zoratto, Federica, Bruna, Riccardo, Sureda, Anna, Martinez-Vila, Clara, Cantini, Luca, Mazzoni, Francesca, Grosso, Federica, Parisi, Alessandro, Saponara, Maristella, Prat, Aleix, Pinato, David J., Cortellini, Alessio, Salazar, Ramon, Gennari, Alessandra, Aguilar-Company, Juan, Bower, Mark, Bertuzzi, Alexia, Brunet, Joan, Lambertini, Matteo, Maluquer, Clara, Pedrazzoli, Paolo, Lee, Alvin JX, Carmona-García, MCarmen C., Newsom-Davis, Thomas, Van Hemelrijck, Mieke, Plaja, Andrea, Zambelli, Alberto, Tondini, Carlo, Generali, Daniele, Bertulli, Rossella, Diamantis, Nikolaos, Mukherjee, Uma, Rizzo, Gianpiero, Yu, Tamara, Zoratto, Federica, Bruna, Riccardo, Sureda, Anna, Martinez-Vila, Clara, Cantini, Luca, Mazzoni, Francesca, Grosso, Federica, Parisi, Alessandro, Saponara, Maristella, Prat, Aleix, and Pinato, David J.
- Abstract
Introduction: A significant proportion of patients with cancer who recover from Coronavirus Disease 2019 (COVID-19) may experience COVID-19 sequelae in the early post-infection phase, which negatively affect their continuity of care and oncological outcome. The long-term prevalence and clinical impact of the post-COVID-19 syndrome in patients with cancer are largely unknown. Methods: In this study, we describe the time course of COVID-19 sequelae in patients with non-advanced cancers enrolled in the OnCovid registry. Results: Overall, 186 patients were included, with a median observation period of 9.9 months (95%CI:8,8–11.3) post-COVID-19 resolution. After a median interval of 2.3 months post-COVID-19 (interquartile range: 1.4–3.7), 31 patients (16.6%) reported ≥1 sequelae, including respiratory complications (14, 7.6%), fatigue (13, 7.1%), neuro-cognitive sequelae (7, 3.8%). The vast majority of the patients were not vaccinated prior to COVID-19. COVID-19-related sequelae persisted in 9.8% and 8% of patients 6 and 12 months after COVID-19 resolution. Persistence of sequelae at first oncological follow-up was associated with history of complicated COVID-19 (45.2% vs 24.8%, p = 0.0223), irrespective of oncological features at COVID-19 diagnosis. Conclusion: This study confirms for the first time that, in a largely unvaccinated population, post-COVID-19 syndrome can affect a significant proportion of patients with non-advanced cancer who recovered from the acute illness. COVID-19 sequelae may persist up to 12 months in some patients, highlighting the need for dedicated prevention and supportive strategies.
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- 2022
17. Real-World Outcomes with Ipilimumab and Nivolumab in Advanced Melanoma: A Multicentre Retrospective Study
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Serra-Bellver, Patricio, primary, Versluis, Judith M., additional, Oberoi, Honey K., additional, Zhou, Cong, additional, Slattery, Timothy D., additional, Khan, Yasir, additional, Patrinely, James R., additional, Pires da Silva, Ines, additional, Martinez-Vila, Clara, additional, Cook, Natalie, additional, Graham, Donna, additional, Carlino, Matteo, additional, Menzies, Alexander M., additional, Arance, Ana M., additional, Douglas, Douglas B., additional, Long, Georgina V., additional, Pickering, Lisa, additional, Larkin, James M. G., additional, Blank, Christian U., additional, and Lorigan, Paul, additional
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- 2022
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18. Prevalence and impact of COVID-19 sequelae on treatment and survival of patients with cancer who recovered from SARS-CoV-2 infection: evidence from the OnCovid retrospective, multicentre registry study
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Pinato, David J, primary, Tabernero, Josep, additional, Bower, Mark, additional, Scotti, Lorenza, additional, Patel, Meera, additional, Colomba, Emeline, additional, Dolly, Saoirse, additional, Loizidou, Angela, additional, Chester, John, additional, Mukherjee, Uma, additional, Zambelli, Alberto, additional, Dalla Pria, Alessia, additional, Aguilar-Company, Juan, additional, Ottaviani, Diego, additional, Chowdhury, Amani, additional, Merry, Eve, additional, Salazar, Ramon, additional, Bertuzzi, Alexia, additional, Brunet, Joan, additional, Lambertini, Matteo, additional, Tagliamento, Marco, additional, Pous, Anna, additional, Sita-Lumsden, Ailsa, additional, Srikandarajah, Krishnie, additional, Colomba, Johann, additional, Pommeret, Fanny, additional, Seguí, Elia, additional, Generali, Daniele, additional, Grisanti, Salvatore, additional, Pedrazzoli, Paolo, additional, Rizzo, Gianpiero, additional, Libertini, Michela, additional, Moss, Charlotte, additional, Evans, Joanne S, additional, Russell, Beth, additional, Harbeck, Nadia, additional, Vincenzi, Bruno, additional, Biello, Federica, additional, Bertulli, Rossella, additional, Liñan, Raquel, additional, Rossi, Sabrina, additional, Carmona-García, Maria Carmen, additional, Tondini, Carlo, additional, Fox, Laura, additional, Baggi, Alice, additional, Fotia, Vittoria, additional, Parisi, Alessandro, additional, Porzio, Giampero, additional, Saponara, Maristella, additional, Cruz, Claudia Andrea, additional, García-Illescas, David, additional, Felip, Eudald, additional, Roqué Lloveras, Ariadna, additional, Sharkey, Rachel, additional, Roldán, Elisa, additional, Reyes, Roxana, additional, Earnshaw, Irina, additional, Ferrante, Daniela, additional, Marco-Hernández, Javier, additional, Ruiz-Camps, Isabel, additional, Gaidano, Gianluca, additional, Patriarca, Andrea, additional, Bruna, Riccardo, additional, Sureda, Anna, additional, Martinez-Vila, Clara, additional, Sanchez de Torre, Ana, additional, Cantini, Luca, additional, Filetti, Marco, additional, Rimassa, Lorenza, additional, Chiudinelli, Lorenzo, additional, Franchi, Michela, additional, Krengli, Marco, additional, Santoro, Armando, additional, Prat, Aleix, additional, Van Hemelrijck, Mieke, additional, Diamantis, Nikolaos, additional, Newsom-Davis, Thomas, additional, Gennari, Alessandra, additional, Cortellini, Alessio, additional, Swallow, Judith, additional, Chung, Chris, additional, Dettorre, Gino, additional, Chopra, Neha, additional, Lee, Alvin JX, additional, Sng, Christopher CT, additional, Wong, Yien Ning Sophia, additional, Galazi, Myria, additional, Benafif, Sarah, additional, Dileo, Palma, additional, Patel, Grisma, additional, Wu, Anjui, additional, Sinclair, Alasdair, additional, Soosaipillai, Gehan, additional, Jones, Eleanor, additional, Jackson, Amanda, additional, Piccart, Martine, additional, Colomba-Blameble, Emeline, additional, Cruz, Claudia A, additional, Segui, Elia, additional, Garcia Illescas, David, additional, Mirallas, Oriol, additional, Carbó, Anna, additional, Garcia, Isabel, additional, Wuerstlein, Rachel, additional, Mesia, Ricard, additional, Maluquer, Clara, additional, D'Avanzo, Francesca, additional, Tonini, Giuseppe, additional, Provenzano, Salvatore, additional, Tovazzi, Valeria, additional, Ficorella, Corrado, additional, Queirolo, Paola, additional, Giusti, Raffaele, additional, Mazzoni, Francesca, additional, Zoratto, Federica, additional, Tucci, Marco, additional, Berardi, Rossana, additional, Guida, Annalisa, additional, Bracarda, Sergio, additional, and Iglesias, Maria, additional
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- 2021
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19. Molecular Markers and Targets in Melanoma
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Teixido, Cristina, primary, Castillo, Paola, additional, Martinez-Vila, Clara, additional, Arance, Ana, additional, and Alos, Llucia, additional
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- 2021
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20. Determinants of enhanced vulnerability to COVID-19 in UK cancer patients: a European Study
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Pinato, David J., Scotti, Lorenza, Gennari, Alessandra, Colomba-Blameble, Emeline, Dolly, Saoirse, Loizidou, Angela, Chester, John, Mukherjee, Uma, Zambelli, Alberto, Aguilar-Company, Juan, Bower, Mark, Galazi, Myria, Salazar, Ramon, Bertuzzi, Alexia, Brunet, Joan, Mesia, Ricard, Sita-Lumsden, Ailsa, Colomba, Johann, Pommeret, Fanny, Seguí, Elia, Biello, Federica, Generali, Daniele, Grisanti, Salvatore, Rizzo, Gianpiero, Libertini, Michela, Moss, Charlotte, Evans, Joanne S., Russell, Beth, Wuerstlein, Rachel, Vincenzi, Bruno, Bertulli, Rossella, Ottaviani, Diego, Liñan, Raquel, Marrari, Andrea, Carmona-García, M. Carmen, Sng, Christopher CT., Tondini, Carlo, Mirallas, Oriol, Tovazzi, Valeria, Fotia, Vittoria, Cruz, Claudia Andrea, Saoudi-Gonzalez, Nadia, Felip, Eudald, Roqué Lloveras, Ariadna, Lee, Alvin J.X., Newsom-Davis, Thomas, Sharkey, Rachel, Chung, Chris, García-Illescas, David, Reyes, Roxana, Sophia Wong, Yien Ning, Ferrante, Daniela, Marco-Hernández, Javier, Ruiz-Camps, Isabel, Gaidano, Gianluca, Patriarca, Andrea, Sureda, Anna, Martinez-Vila, Clara, Sanchez de Torre, Ana, Rimassa, Lorenza, Chiudinelli, Lorenzo, Franchi, Michela, Krengli, Marco, Santoro, Armando, Prat, Aleix, Tabernero, Josep, Van Hemelrijck, Mieke, Diamantis, Nikolaos, and Cortellini, Alessio
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Europe ,SARS-CoV-2 ,COVID-19 ,cancer ,UK ,Mortality ,Original Research - Abstract
Background Despite high contagiousness and rapid spread, SARS-CoV-2 has led to heterogeneous outcomes across affected nations. Within Europe, the United Kingdom (UK) is the most severely affected country, with a death toll in excess of 100.000 as of January 2021. We aimed to compare the national impact of COVID-19 on the risk of death in UK cancer patients versus those in continental Europe (EU). Methods We performed a retrospective analysis of the OnCovid study database, a European registry of cancer patients consecutively diagnosed with COVID-19 in 27 centres from February 27 to September 10, 2020. We analysed case fatality rates and risk of death at 30 days and 6 months stratified by region of origin (UK versus EU). We compared patient characteristics at baseline, including oncological and COVID-19 specific therapy across UK and EU cohorts and evaluated the association of these factors with the risk adverse outcome in multivariable Cox regression models. Findings Compared to EU (n=924), UK patients (n=468) were characterised by higher case fatality rates (40.38% versus 26.5%, p
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- 2021
21. Determinants of enhanced vulnerability to coronavirus disease 2019 in UK patients with cancer: a European study
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Pinato, David J., primary, Scotti, Lorenza, additional, Gennari, Alessandra, additional, Colomba-Blameble, Emeline, additional, Dolly, Saoirse, additional, Loizidou, Angela, additional, Chester, John, additional, Mukherjee, Uma, additional, Zambelli, Alberto, additional, Aguilar-Company, Juan, additional, Bower, Mark, additional, Galazi, Myria, additional, Salazar, Ramon, additional, Bertuzzi, Alexia, additional, Brunet, Joan, additional, Mesia, Ricard, additional, Sita-Lumsden, Ailsa, additional, Colomba, Johann, additional, Pommeret, Fanny, additional, Seguí, Elia, additional, Biello, Federica, additional, Generali, Daniele, additional, Grisanti, Salvatore, additional, Rizzo, Gianpiero, additional, Libertini, Michela, additional, Moss, Charlotte, additional, Evans, Joanne S., additional, Russell, Beth, additional, Wuerstlein, Rachel, additional, Vincenzi, Bruno, additional, Bertulli, Rossella, additional, Ottaviani, Diego, additional, Liñan, Raquel, additional, Marrari, Andrea, additional, Carmona-García, M.C., additional, Sng, Christopher. C.T., additional, Tondini, Carlo, additional, Mirallas, Oriol, additional, Tovazzi, Valeria, additional, Fotia, Vittoria, additional, Cruz, Claudia A., additional, Saoudi-Gonzalez, Nadia, additional, Felip, Eudald, additional, R. Lloveras, Ariadna, additional, Lee, Alvin. J.X., additional, Newsom-Davis, Thomas, additional, Sharkey, Rachel, additional, Chung, Chris, additional, García-Illescas, David, additional, Reyes, Roxana, additional, Sophia Wong, Yien N., additional, Ferrante, Daniela, additional, Marco-Hernández, Javier, additional, Ruiz-Camps, Isabel, additional, Gaidano, Gianluca, additional, Patriarca, Andrea, additional, Sureda, Anna, additional, Martinez-Vila, Clara, additional, Sanchez de Torre, Ana, additional, Rimassa, Lorenza, additional, Chiudinelli, Lorenzo, additional, Franchi, Michela, additional, Krengli, Marco, additional, Santoro, Armando, additional, Prat, Aleix, additional, Tabernero, Josep, additional, V. Hemelrijck, Mieke, additional, Diamantis, Nikolaos, additional, and Cortellini, Alessio, additional
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- 2021
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22. sj-docx-1-tam-10.1177_17588359211053416 ��� Supplemental material for COVID-19 in breast cancer patients: a subanalysis of the OnCovid registry
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Garrig��s, Laia, Saura, Cristina, Martinez-Vila, Clara, Zambelli, Alberto, Bower, Mark, Pistilli, Barbara, Lambertini, Matteo, Ottaviani, Diego, Diamantis, Nikolaos, Lumsden, Ailsa, Pernas, Sonia, Generali, Daniele, Segu��, Elia, Vi��as, Gemma, Felip, Eudald, Sanchez, Ana, Rizzo, Gianpiero, Santoro, Armando, Cortellini, Alessio, Perone, Ylenia, Chester, John, Iglesias, Maria, Betti, Marta, Vincenzi, Bruno, Libertini, Michela, Mazzoni, Francesca, Zoratto, Federica, Berardi, Rossana, Guida, Annalisa, Wuerstlein, Rachel, Loizidou, Angela, Sharkey, Rachel, Aguilar Company, Juan, Matas, Marta, Saggia, Chiara, Chiudinelli, Lorenzo, Colomba-Blameble, Emeline, Galazi, Myria, Mukherjee, Uma, Van Hemelrijck, Mieke, Marin, Mar, Strina, Carla, Prat, Aleix, Pla, Helena, Ciruelos, Eva Maria, Bertuzzi, Alexia, del Mastro, Lucia, Porzio, Giampiero, Newsom-Davis, Thomas, Ruiz, Isabel, Delany, Maria Belen, Krengli, Marco, Fotia, Vittoria, Viansone, Alessandro, Chopra, Neha, Romeo, Margarita, Salazar, Ramon, Perez, Ignacio, d���Avanzo, Francesca, Franchi, Michela, Milani, Manuela, Pommeret, Fanny, Tucci, Marco, Pedrazzoli, Paolo, Harbeck, Nadia, Ferrante, Daniela, Pinato, David J., and Gennari, Alessandra
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110203 Respiratory Diseases ,FOS: Clinical medicine ,111702 Aged Health Care ,FOS: Health sciences ,111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified ,111299 Oncology and Carcinogenesis not elsewhere classified - Abstract
Supplemental material, sj-docx-1-tam-10.1177_17588359211053416 for COVID-19 in breast cancer patients: a subanalysis of the OnCovid registry by Laia Garrig��s, Cristina Saura, Clara Martinez-Vila, Alberto Zambelli, Mark Bower, Barbara Pistilli, Matteo Lambertini, Diego Ottaviani, Nikolaos Diamantis, Ailsa Lumsden, Sonia Pernas, Daniele Generali, Elia Segu��, Gemma Vi��as, Eudald Felip, Ana Sanchez, Gianpiero Rizzo, Armando Santoro, Alessio Cortellini, Ylenia Perone, John Chester, Maria Iglesias, Marta Betti, Bruno Vincenzi, Michela Libertini, Francesca Mazzoni, Federica Zoratto, Rossana Berardi, Annalisa Guida, Rachel Wuerstlein, Angela Loizidou, Rachel Sharkey, Juan Aguilar Company, Marta Matas, Chiara Saggia, Lorenzo Chiudinelli, Emeline Colomba-Blameble, Myria Galazi, Uma Mukherjee, Mieke Van Hemelrijck, Mar Marin, Carla Strina, Aleix Prat, Helena Pla, Eva Maria Ciruelos, Alexia Bertuzzi, Lucia del Mastro, Giampiero Porzio, Thomas Newsom-Davis, Isabel Ruiz, Maria Belen Delany, Marco Krengli, Vittoria Fotia, Alessandro Viansone, Neha Chopra, Margarita Romeo, Ramon Salazar, Ignacio Perez, Francesca d���Avanzo, Michela Franchi, Manuela Milani, Fanny Pommeret, Marco Tucci, Paolo Pedrazzoli, Nadia Harbeck, Daniela Ferrante, David J. Pinato and Alessandra Gennari in Therapeutic Advances in Medical Oncology
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- 2021
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23. COVID-19 in breast cancer patients: a subanalysis of the OnCovid registry
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Garrigós, Laia, primary, Saura, Cristina, additional, Martinez-Vila, Clara, additional, Zambelli, Alberto, additional, Bower, Mark, additional, Pistilli, Barbara, additional, Lambertini, Matteo, additional, Ottaviani, Diego, additional, Diamantis, Nikolaos, additional, Lumsden, Ailsa, additional, Pernas, Sonia, additional, Generali, Daniele, additional, Seguí, Elia, additional, Viñas, Gemma, additional, Felip, Eudald, additional, Sanchez, Ana, additional, Rizzo, Gianpiero, additional, Santoro, Armando, additional, Cortellini, Alessio, additional, Perone, Ylenia, additional, Chester, John, additional, Iglesias, Maria, additional, Betti, Marta, additional, Vincenzi, Bruno, additional, Libertini, Michela, additional, Mazzoni, Francesca, additional, Zoratto, Federica, additional, Berardi, Rossana, additional, Guida, Annalisa, additional, Wuerstlein, Rachel, additional, Loizidou, Angela, additional, Sharkey, Rachel, additional, Aguilar Company, Juan, additional, Matas, Marta, additional, Saggia, Chiara, additional, Chiudinelli, Lorenzo, additional, Colomba-Blameble, Emeline, additional, Galazi, Myria, additional, Mukherjee, Uma, additional, Van Hemelrijck, Mieke, additional, Marin, Mar, additional, Strina, Carla, additional, Prat, Aleix, additional, Pla, Helena, additional, Ciruelos, Eva Maria, additional, Bertuzzi, Alexia, additional, del Mastro, Lucia, additional, Porzio, Giampiero, additional, Newsom-Davis, Thomas, additional, Ruiz, Isabel, additional, Delany, Maria Belen, additional, Krengli, Marco, additional, Fotia, Vittoria, additional, Viansone, Alessandro, additional, Chopra, Neha, additional, Romeo, Margarita, additional, Salazar, Ramon, additional, Perez, Ignacio, additional, d’Avanzo, Francesca, additional, Franchi, Michela, additional, Milani, Manuela, additional, Pommeret, Fanny, additional, Tucci, Marco, additional, Pedrazzoli, Paolo, additional, Harbeck, Nadia, additional, Ferrante, Daniela, additional, Pinato, David J., additional, and Gennari, Alessandra, additional
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- 2021
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24. Association of Ki67 expression levels and therapy outcome in low-grade serous ovarian cancer.
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Grabowski, J.P. P., primary, Martinez-Vila, Clara, additional, Richter, Rolf, additional, Taube, Eliane T, additional, Braicu, Elena Ioana, additional, and Sehouli, Jalid, additional
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- 2019
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25. Time-Dependent COVID-19 Mortality in Patients With Cancer: An Updated Analysis of the OnCovid Registry
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Pinato, David J., Patel, Meera, Scotti, Lorenza, Colomba, Emeline, Dolly, Saoirse, Loizidou, Angela, Chester, John, Mukherjee, Uma, Zambelli, Alberto, Dalla Pria, Alessia, Aguilar-Company, Juan, Bower, Mark, Salazar, Ramon, Bertuzzi, Alexia, Brunet, Joan, Lambertini, Matteo, Tagliamento, Marco, Pous, Anna, Sita-Lumsden, Ailsa, Srikandarajah, Krishnie, Colomba, Johann, Pommeret, Fanny, Seguí, Elia, Generali, Daniele, Grisanti, Salvatore, Pedrazzoli, Paolo, Rizzo, Gianpiero, Libertini, Michela, Moss, Charlotte, Evans, Joanne S., Russell, Beth, Harbeck, Nadia, Vincenzi, Bruno, Biello, Federica, Bertulli, Rossella, Ottaviani, Diego, Liñan, Raquel, Rossi, Sabrina, Carmona-García, M. Carmen, Tondini, Carlo, Fox, Laura, Baggi, Alice, Fotia, Vittoria, Parisi, Alessandro, Porzio, Giampero, Queirolo, Paola, Cruz, Claudia Andrea, Saoudi-Gonzalez, Nadia, Felip, Eudald, Roqué Lloveras, Ariadna, Newsom-Davis, Thomas, Sharkey, Rachel, Roldán, Elisa, Reyes, Roxana, Zoratto, Federica, Earnshaw, Irina, Ferrante, Daniela, Marco-Hernández, Javier, Ruiz-Camps, Isabel, Gaidano, Gianluca, Patriarca, Andrea, Bruna, Riccardo, Sureda, Anna, Martinez-Vila, Clara, Sanchez de Torre, Ana, Berardi, Rossana, Giusti, Raffaele, Mazzoni, Francesca, Guida, Annalisa, Rimassa, Lorenza, Chiudinelli, Lorenzo, Franchi, Michela, Krengli, Marco, Santoro, Armando, Prat, Aleix, Tabernero, Josep, Van Hemelrijck, Mieke, Diamantis, Nikolaos, Gennari, Alessandra, and Cortellini, Alessio
- Abstract
IMPORTANCE: Whether the severity and mortality of COVID-19 in patients with cancer have improved in terms of disease management and capacity is yet to be defined. OBJECTIVE: To test whether severity and mortality from COVID-19 among patients with cancer have improved during the course of the pandemic. DESIGN, SETTING, AND PARTICIPANTS: OnCovid is a European registry that collects data on consecutive patients with solid or hematologic cancer and COVID-19. This multicenter case series study included real-world data from 35 institutions across 6 countries (UK, Italy, Spain, France, Belgium, and Germany). This update included patients diagnosed between February 27, 2020, and February, 14, 2021. Inclusion criteria were confirmed diagnosis of SARS-CoV-2 infection and a history of solid or hematologic cancer. EXPOSURES: SARS-CoV-2 infection. MAIN OUTCOMES AND MEASURES: Deaths were differentiated at 14 days and 3 months as the 2 landmark end points. Patient characteristics and outcomes were compared by stratifying patients across 5 phases (February to March 2020, April to June 2020, July to September 2020, October to December 2020, and January to February 2021) and across 2 major outbreaks (February to June 2020 and July 2020 to February 2021). RESULTS: At data cutoff, 2795 consecutive patients were included, with 2634 patients eligible for analysis (median [IQR] age, 68 [18-77] years ; 52.8% men). Eligible patients demonstrated significant time-dependent improvement in 14-day case-fatality rate (CFR) with estimates of 29.8% (95% CI, 0.26-0.33) for February to March 2020; 20.3% (95% CI, 0.17-0.23) for April to June 2020; 12.5% (95% CI, 0.06-22.90) for July to September 2020; 17.2% (95% CI, 0.15-0.21) for October to December 2020; and 14.5% (95% CI, 0.09-0.21) for January to February 2021 (all P < .001) across the predefined phases. Compared with the second major outbreak, patients diagnosed in the first outbreak were more likely to be 65 years or older (974 of 1626 [60.3%] vs 564 of 1008 [56.1%]; P = .03), have at least 2 comorbidities (793 of 1626 [48.8%] vs 427 of 1008 [42.4%]; P = .001), and have advanced tumors (708 of 1626 [46.4%] vs 536 of 1008 [56.1%]; P < .001). Complications of COVID-19 were more likely to be seen (738 of 1626 [45.4%] vs 342 of 1008 [33.9%]; P < .001) and require hospitalization (969 of 1626 [59.8%] vs 418 of 1008 [42.1%]; P < .001) and anti–COVID-19 therapy (1004 of 1626 [61.7%] vs 501 of 1008 [49.7%]; P < .001) during the first major outbreak. The 14-day CFRs for the first and second major outbreaks were 25.6% (95% CI, 0.23-0.28) vs 16.2% (95% CI, 0.13-0.19; P < .001), respectively. After adjusting for country, sex, age, comorbidities, tumor stage and status, anti–COVID-19 and anticancer therapy, and COVID-19 complications, patients diagnosed in the first outbreak had an increased risk of death at 14 days (hazard ratio [HR], 1.85; 95% CI, 1.47-2.32) and 3 months (HR, 1.28; 95% CI, 1.08-1.51) compared with those diagnosed in the second outbreak. CONCLUSIONS AND RELEVANCE: The findings of this registry-based study suggest that mortality in patients with cancer diagnosed with COVID-19 has improved in Europe; this improvement may be associated with earlier diagnosis, improved management, and dynamic changes in community transmission over time.
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- 2022
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26. Determinants of enhanced vulnerability to coronavirus disease 2019 in UK patients with cancer: a European study
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Elia Seguí, Nadia Saoudi-Gonzalez, Federica Biello, Rachel Wuerstlein, Andrea Marrari, Carlo Tondini, Ramon Salazar, Lorenza Rimassa, Claudia Andrea Cruz, Nikolaos Diamantis, David J. Pinato, Armando Santoro, Salvatore Grisanti, Clara Martinez-Vila, Charlotte Moss, Lorenzo Chiudinelli, Daniele Generali, M. C. Carmona-Garcia, Vittoria Fotia, Alexia Bertuzzi, Ailsa Sita-Lumsden, Angela Loizidou, Christopher C T Sng, Bruno Vincenzi, Alessandra Gennari, Aleix Prat, David García-Illescas, Chris Chung, Fanny Pommeret, Diego Ottaviani, Daniela Ferrante, Ariadna Roqué Lloveras, Joan Brunet, Johann Colomba, Joanne Evans, Uma Mukherjee, Alvin J.X. Lee, Juan Aguilar-Company, Andrea Patriarca, Myria Galazi, Gianluca Gaidano, Javier Marco-Hernández, Eudald Felip, Marco Krengli, Gianpiero Rizzo, Isabel Ruiz-Camps, Thomas Newsom-Davis, Mark Bower, John D. Chester, Saoirse Dolly, Yien N. Sophia Wong, Ricard Mesia, Michela Franchi, Michela Libertini, Alessio Cortellini, Roxana Reyes, Lorenza Scotti, Josep Tabernero, Rossella Bertulli, Oriol Mirallas, Valeria Tovazzi, Emeline Colomba-Blameble, Anna Sureda, Beth Russell, Raquel Liñan, Rachel Sharkey, Mieke Van Hemelrijck, Alberto Zambelli, Ana Sanchez de Torre, Pinato, David J., Scotti, Lorenza, Gennari, Alessandra, Colomba-Blameble, Emeline, Dolly, Saoirse, Loizidou, Angela, Chester, John, Mukherjee, Uma, Zambelli, Alberto, Aguilar-Company, Juan, Bower, Mark, Galazi, Myria, Salazar, Ramon, Bertuzzi, Alexia, Brunet, Joan, Mesia, Ricard, Sita-Lumsden, Ailsa, Colomba, Johann, Pommeret, Fanny, Seguí, Elia, Biello, Federica, Generali, Daniele, Grisanti, Salvatore, Rizzo, Gianpiero, Libertini, Michela, Moss, Charlotte, Evans, Joanne S., Russell, Beth, Wuerstlein, Rachel, Vincenzi, Bruno, Bertulli, Rossella, Ottaviani, Diego, Liñan, Raquel, Marrari, Andrea, Carmona-García, M. C., Sng, Christopher. C. T., Tondini, Carlo, Mirallas, Oriol, Tovazzi, Valeria, Fotia, Vittoria, Cruz, Claudia A., Saoudi-Gonzalez, Nadia, Felip, Eudald, R. Lloveras, Ariadna, Lee, Alvin. J. X., Newsom-Davis, Thoma, Sharkey, Rachel, Chung, Chri, García-Illescas, David, Reyes, Roxana, Sophia Wong, Yien N., Ferrante, Daniela, Marco-Hernández, Javier, Ruiz-Camps, Isabel, Gaidano, Gianluca, Patriarca, Andrea, Sureda, Anna, Martinez-Vila, Clara, Sanchez de Torre, Ana, Rimassa, Lorenza, Chiudinelli, Lorenzo, Franchi, Michela, Krengli, Marco, Santoro, Armando, Prat, Aleix, Tabernero, Josep, V. Hemelrijck, Mieke, Diamantis, Nikolao, and Cortellini, Alessio
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0301 basic medicine ,Cancer Research ,medicine.medical_specialty ,medicine.medical_treatment ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,Epidemiology ,Case fatality rate ,medicine ,COVID-19 ,Cancer ,Europe ,Mortality ,SARS-CoV-2 ,UK ,Mechanical ventilation ,business.industry ,Proportional hazards model ,medicine.disease ,Comorbidity ,Confidence interval ,030104 developmental biology ,Oncology ,030220 oncology & carcinogenesis ,Cohort ,business - Abstract
Background: Despite high contagiousness and rapid spread, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to heterogeneous outcomes across affected nations. Within Europe (EU), the United Kingdom (UK) is the most severely affected country, with a death toll in excess of 100,000 as of January 2021. We aimed to compare the national impact of coronavirus disease 2019 (COVID-19) on the risk of death in UK patients with cancer versus those in continental EU. Methods: We performed a retrospective analysis of the OnCovid study database, a European registry of patients with cancer consecutively diagnosed with COVID-19 in 27 centres from 27th February to 10th September 2020. We analysed case fatality rates and risk of death at 30 days and 6 months stratified by region of origin (UK versus EU). We compared patient characteristics at baseline including oncological and COVID-19-specific therapy across UKand EU cohorts and evaluated the association of these factors with the risk of adverse out-comes in multivariable Cox regression models Findings: Compared with EU (n = 924), UK patients (n = 468) were characterised by higher case fatality rates (40.38% versus 26.5%, p < 0.0001) and higher risk of death at 30 days (haz-ard ratio [HR], 1.64 [95% confidence interval {CI}, 1.36-1.99]) and 6 months after COVID-19 diagnosis (47.64% versus 33.33%; p < 0.0001; HR, 1.59 [95% CI, 1.33-1.88]). UK patients were more often men, were of older age and have more comorbidities than EU counterparts (p < 0.01). Receipt of anticancer therapy was lower in UK than in EU patients (p < 0.001). Despite equal proportions of complicated COVID-19, rates of intensive care admission and use of mechanical ventilation, UK patients with cancer were less likely to receive anti-COVID-19 therapies including corticosteroids, antivirals and inter leukin-6 antagonists (p < 0.0001). Multivariable analyses adjusted for imbalanced prognostic factors confirmed the UK cohort to be characterised by worse risk of death at 30 days and 6 months, indepen-dent of the patient's age, gender, tumour stage and status; number of comorbidities; COVID-19 severity and receipt of anticancer and anti-COVID-19 therapy. Rates of permanent cessa-tion of anticancer therapy after COVID-19 were similar in the UK and EU cohorts. Interpretation: UK patients with cancer have been more severely impacted by the unfolding of the COVID-19 pandemic despite societal risk mitigation factors and rapid deferral of anti-cancer therapy. The increased frailty of UK patients with cancer highlights high-risk groups that should be prioritised for anti-SARS-CoV-2 vaccination. Continued evaluation of long-term outcomes is warranted. (C) 2021 Elsevier Ltd. All rights reserved.
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- 2021
27. COVID-19 Sequelae and the Host Proinflammatory Response: An Analysis From the OnCovid Registry.
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Cortellini A, Gennari A, Pommeret F, Patel G, Newsom-Davis T, Bertuzzi A, Viladot M, Aguilar-Company J, Mirallas O, Felip E, Lee AJX, Dalla Pria A, Sharkey R, Brunet J, Carmona-García M, Chester J, Mukherjee U, Scotti L, Dolly S, Sita-Lumsden A, Ferrante D, Van Hemelrijck M, Moss C, Russell B, Seguí E, Biello F, Krengli M, Marco-Hernández J, Gaidano G, Patriarca A, Bruna R, Roldán E, Fox L, Pous A, Griscelli F, Salazar R, Martinez-Vila C, Sureda A, Loizidou A, Maluquer C, Stoclin A, Iglesias M, Pedrazzoli P, Rizzo G, Santoro A, Rimassa L, Rossi S, Harbeck N, Sanchez de Torre A, Vincenzi B, Libertini M, Provenzano S, Generali D, Grisanti S, Berardi R, Tucci M, Mazzoni F, Lambertini M, Tagliamento M, Parisi A, Zoratto F, Queirolo P, Giusti R, Guida A, Zambelli A, Tondini C, Maconi A, Betti M, Colomba E, Diamantis N, Sinclair A, Bower M, Ruiz-Camps I, and Pinato DJ
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- C-Reactive Protein analysis, COVID-19 Testing, Disease Progression, Humans, Lactate Dehydrogenases, Lymphocytes chemistry, Neutrophils chemistry, Prognosis, ROC Curve, Registries, Retrospective Studies, COVID-19 complications, COVID-19 epidemiology
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Background: Fifteen percent of patients with cancer experience symptomatic sequelae, which impair post-COVID-19 outcomes. In this study, we investigated whether a proinflammatory status is associated with the development of COVID-19 sequelae., Methods: OnCovid recruited 2795 consecutive patients who were diagnosed with Severe Acute Respiratory Syndrome Coronavirus 2 infection between February 27, 2020, and February 14, 2021. This analysis focused on COVID-19 survivors who underwent a clinical reassessment after the exclusion of patients with hematological malignancies. We evaluated the association of inflammatory markers collected at COVID-19 diagnosis with sequelae, considering the impact of previous systemic anticancer therapy. All statistical tests were 2-sided., Results: Of 1339 eligible patients, 203 experienced at least 1 sequela (15.2%). Median baseline C-reactive protein (CRP; 77.5 mg/L vs 22.2 mg/L, P < .001), lactate dehydrogenase (310 UI/L vs 274 UI/L, P = .03), and the neutrophil to lymphocyte ratio (NLR; 6.0 vs 4.3, P = .001) were statistically significantly higher among patients who experienced sequelae, whereas no association was reported for the platelet to lymphocyte ratio and the OnCovid Inflammatory Score, which includes albumin and lymphocytes. The widest area under the ROC curve (AUC) was reported for baseline CRP (AUC = 0.66, 95% confidence interval [CI]: 0.63 to 0.69), followed by the NLR (AUC = 0.58, 95% CI: 0.55 to 0.61) and lactate dehydrogenase (AUC = 0.57, 95% CI: 0.52 to 0.61). Using a fixed categorical multivariable analysis, high CRP (odds ratio [OR] = 2.56, 95% CI: 1.67 to 3.91) and NLR (OR = 1.45, 95% CI: 1.01 to 2.10) were confirmed to be statistically significantly associated with an increased risk of sequelae. Exposure to chemotherapy was associated with a decreased risk of sequelae (OR = 0.57, 95% CI: 0.36 to 0.91), whereas no associations with immune checkpoint inhibitors, endocrine therapy, and other types of systemic anticancer therapy were found., Conclusions: Although the association between inflammatory status, recent chemotherapy and sequelae warrants further investigation, our findings suggest that a deranged proinflammatory reaction at COVID-19 diagnosis may predict for sequelae development., (© The Author(s) 2022. Published by Oxford University Press. All rights reserved. For permissions, please email: journals.permissions@oup.com.)
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- 2022
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