1. Voltammetric Determination of Cocaine in Confiscated Samples Using a Carbon Paste Electrode Modified with Different [UO2(X-MeOsalen)(H2O)]·H2O Complexes
- Author
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Marcelo Firmino de Oliveira, Heloísa Maria Tristão, Edward Ralph Dockal, José Fernando de Andrade, Marco Antonio Balbino, Matheus Manoel Teles de Menezes, Ana Paula dos Santos Poles, and Laura Siqueira de Oliveira
- Subjects
forensic chemistry ,cocaine ,Schiff base complexes ,chemically modified electrodes ,cyclic voltammetry ,Chemical technology ,TP1-1185 - Abstract
A fast and non-destructive voltammetric method to detect cocaine in confiscated samples based on carbon paste electrode modified with methoxy-substituted N,N'-ethylene-bis(salcylideneiminato)uranyl(VI)complexes, [UO2(X-MeOSalen)(H2O)]·H2O, where X corresponds to the positions 3, 4 or 5 of the methoxy group on the aromatic ring, is described. The electrochemical behavior of the modified electrode and the electrochemical detection of cocaine were investigated using cyclic voltammetry. Using 0.1 mol·L−1 KCl as supporting-electrolyte, a concentration-dependent, well-defined peak current for cocaine at 0.62 V, with an amperometric sensitivity of 6.25 × 104 μA·mol·L−1 for cocaine concentrations ranging between 1.0 × 10−7 and 1.3 × 10−6 mol·L−1 was obtained. Chemical interference studies using lidocaine and procaine were performed. The position of the methoxy group affects the results, with the 3-methoxy derivative being the most sensitive.
- Published
- 2013
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