Search

The article substantiates the synergistic concept of complex linguistic and rhetorical (L&R) training necessary for the high-quality professional training of a future specialist of any direction and profile of higher school education; the specification is made on the example of a teacher of a foreign language (foreign languages). The restructuring of the educational process in the framework of the bi/polylinguistic learning model developed by representatives of the Sochi L&R School is based on the positions set out in the article. For the development of a professional bi/polylinguistic personality of a future specialist, more effective than the specialized formation of the L&R competence only in the field of foreign languages is the purposeful and coordinated work of the entire teaching staff in the framework of "the single linguistic-rhetorical and cultural-speech regime" according to the formation of Russian and foreign language L&R competencies of learners. The speech-thinking culture of future specialists, integrating in a bi/polylinguistic relation, including an invariant core and ethno-linguistic- rhetorical variants, is a qualitatively new psycholinguistic formation, which is formed on the basis of the interaction of the substructures of the primary and secondary linguistic personality. A necessary condition for the formation of speech-thinking culture of future specialists is the formation of students' readiness for professional self-designing as a future specialist on the basis of a bi/polylinguistic L&R competence of mixed type.

This research aims to explore the impact of educational environment factors within higher education institutions on the process of shaping professional (Hard Skills) and social competencies (Soft Skills) of future professionals. The proposed study falls within the realm of mixed-method scientific inquiry, as it encompasses the synthesis of theoretical analysis of scholarly concepts relevant to the article's core ideas, a factor analysis of empirical data collected to quantify the influence of external and internal educational environment factors, as well as qualitative generalizations drawn from the results of the factor analysis. Empirical data collection was conducted through the observation of a student group (n = 925) utilizing methods such as surveys, questionnaires, testing, and interviews. The findings of this research are valuable for informing the implementation of models for graduates of higher education institutions. The study revealed that future professionals are expected to have not only hard skills but also develop soft skills, the formation of which should occur in parallel. [ABSTRACT FROM AUTHOR]

This article provides a summary of discussions from the American Statistical Association (ASA) Biopharmaceutical (BIOP) Section Open Forum organized by the ASA BIOP Statistical Methods in Oncology Scientific Working Group in coordination with the US FDA Oncology Center of Excellence and LUNGevity Foundation on June 24, 2021, and January 13, 2022. Diverse stakeholders engaged in a discussion on how best to use various innovative clinical trial designs in designing future pediatric oncology trials. While standard randomized controlled trials are preferred to evaluate treatment effect in an unbiased manner, given the rarity of pediatric cancers, innovative strategies are needed to promote and assure timely cancer drug development in pediatric populations. The discussions highlighted the need to consider innovative designs with less stringent Type I error specification and Bayesian designs borrowing from external control data, or borrowing treatment effect information from adult data, or both. Such designs are available in the literature and some examples are summarized under the FDA Complex Innovative Trials Design Pilot Program (https://www.fda.gov/drugs/development-resources/complex-innovative-trial-design-meeting-program). Early consultation with global regulatory agencies for pediatric clinical trials can provide a better understanding of different features of the clinical trial design options for successful pediatric cancer drug development. [ABSTRACT FROM AUTHOR]

This article provides a summary of discussions from the American Statistical Association (ASA) Biopharmaceutical (BIOP) Section Open Forum on April 8, 2021, and May 13, 2021, organized by the ASA BIOP Statistical Methods in Oncology Scientific Working Group in coordination with the United States Food and Drug Administration (U.S. FDA) Oncology Center of Excellence (OCE) and LUNGevity Foundation. In most cancer trials, disproportionately low numbers of older adults and certain racial minority groups are enrolled, even though a high incidence of cancer is observed in these subpopulations. This results in a lack of sufficient information on efficacy and safety of new treatments in such demographic subpopulations. Discussions with a diverse group of stakeholders including oncologists, patient advocates, experts from international regulatory agencies, academicians, and representatives of the pharmaceutical industry focused on designing future pre- and post-market studies to evaluate treatment effect in demographically underrepresented (UR) cancer populations such as racial and ethnic minority groups and older adults. It is noted that often there is poor or no representation of pediatric cancer patients as well. However, not all adult cancers are observed in pediatric patients and vice-a-versa and these discussions mainly focused on adult cancers. It is recognized that inclusion of broader patient populations can introduce heterogeneity and if the trial includes patients with more comorbidities or poorer prognosis may increase the chances of rejecting an effective therapy. However, there are clinical trial designs and statistical methods to include and evaluate treatment effects in UR cancer patients. Importantly, a commitment and a concerted effort from all stakeholders to change the current practice is necessary to better understand the benefit/risk in these demographically UR patients in cancer clinical trials. [ABSTRACT FROM AUTHOR]

In the article the financial factors affecting innovation, and examined the structure of industries industrial complex of Ukraine on technological structure of production.В статье определены финансовые факторы, влияющие на инновационную деятельность, и рассмотрена структура отраслей промышленного комплекса Украины по технологическим укладам производства.

The study is related to the pedagogical experiment on the systemic controlled impact on the formation of educational environment in higher educational institutions. The article aims to verify the effectiveness of introducing the pedagogical system of educational environment formation in higher educational institutions on the example of an aviation educational institution. Evaluation of the effectiveness of the pedagogical system of educational environment formation is based on the monitoring analysis. Diagnostic techniques of the expert examination have been described. The statistical insignificance of discrepancies between the data of control and experimental samples has been proved. Significant changes in the educational environment formation levels in the control and experimental groups have been confirmed. [ABSTRACT FROM AUTHOR]