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32 results on '"Magaziner, Jay S."'

1. Advancing clinical trials in nursing homes: A proposed roadmap to success

Author

Gurwitz, Jerry H., Quinn, Charlene C., Abi-Elias, Ivan H., Adams, Alyce S., Bartel, Rosie, Bonner, Alice, Boxer, Rebecca, Delude, Christopher, Gifford, David, Hanson, Bruce, Ito, Kouta, Jain, Paavani, Magaziner, Jay S., Mazor, Kathleen M., Mitchell, Susan L., Mody, Lona, Nace, David, Ouslander, Joseph, Reifsnyder, JoAnne, Resnick, Barbara, and Zimmerman, Sheryl

Published
2022
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7. Advancing Clinical Trials in Nursing Homes: A Proposed Roadmap to Success

Author

Gurwitz, Jerry H., primary, Quinn, Charlene C., additional, Abi-Elias, Ivan H., additional, Adams, Alyce S., additional, Bartel, Rosie, additional, Bonner, Alice, additional, Boxer, Rebecca, additional, Delude, Christopher, additional, Gifford, David, additional, Hanson, Bruce, additional, Ito, Kouta, additional, Jain, Paavani, additional, Magaziner, Jay S., additional, Mazor, Kathleen M., additional, Mitchell, Susan L., additional, Mody, Lona, additional, Nace, David, additional, Ouslander, Joseph, additional, Reifsnyder, JoAnne, additional, Resnick, Barbara, additional, and Zimmerman, Sheryl, additional

Published
2022
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11. Own the Fall

Author

Anderson, Paul A., primary, Magaziner, Jay S., additional, Mendelson, Daniel Ari, additional, and Switzer, Julie A., additional

Published
2021
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15. Zoledronic acid and clinical fractures and mortality after hip fracture

Author

Lyles, Kenneth W., Colon-Emeric, Cathleen S., Magaziner, Jay S., Adachi, Jonathan D., Pieper, Carl F., Mautalen, Carlos, Hyldstrup, Lars, Recknor, Chris, Nordsletten, Lars, Moore, Kathy A., Lavecchia, Catherine, Jie Zhang, Mesenbrink, Peter, Hodgson, Patricia K., Abrams, Ken, Orloff, John J., Horowitz, Zebulun, Eriksen, Erik Fink, and Boonen, Steven

Subjects
Zoledronic acid -- Patient outcomes, Zoledronic acid -- Research, Hip joint -- Fractures, Hip joint -- Drug therapy, Hip joint -- Care and treatment, Hip joint -- Prevention
Abstract

The effectiveness of zoledronic acid in prevention of new clinical fractures, to patients undergone hip fracture surgery is studied. Results concluded yearly infusion of zoledronic acid within 90 days of hip fracture surgery reduced risk of new clinical fractures raising survival rate.

Published
2007

16. Differential misclassification of cognitive impairment by sex among hip fracture patients.

Author

Mutchie, Heather L., Albrecht, Jennifer S., Orwig, Denise L., Huang, Yi, Boscardin, W. John, Hochberg, Marc C., Magaziner, Jay S., and Gruber‐Baldini, Ann L.

Subjects
COGNITION disorders diagnosis, COGNITION disorders, HOSPITALS, ALZHEIMER'S disease, CROSS-sectional method, CONVALESCENCE, HIP fractures, SURGICAL complications, HEALTH status indicators, SEX distribution, DOCUMENTATION, INDEPENDENT living, MEDICAL records, QUESTIONNAIRES, LOGISTIC regression analysis, COGNITIVE testing, LONGITUDINAL method, COMORBIDITY
Abstract

Background: Males have worse outcomes after hip fracture than female counterparts. Cognitive impairment (CI) also increases the risk of poor recovery from hip fracture; however, CI is under‐recognized. Patient sex may contribute to this under‐recognition through differential misclassification. The objective of this study was to measure under‐recognition and differential misclassification of CI by patient sex. Methods: A cross‐sectional analysis of baseline data from an observational cohort study of community‐dwelling hip fracture patients aged 65 and older (n = 339; females = 171, males = 168) recruited from eight hospitals in the greater Baltimore, MD area within 15 days of hospitalization for surgical repair with cognitive testing within 22 days of admission. Indication of Alzheimer's disease or related dementias and/or delirium as a postoperative complication in the medical record was considered evidence of documented CI. Observed CI was measured with the Modified Mini‐Mental State Examination (3MS, ≤78). Source of cognitive impairment identification (SCI) was defined as: "3MS Only," "Hospital Record Only," "Both," "No CI" was compared between males and females using logistic regression. Results: Males had more comorbidities and worse physical status upon admission, but otherwise had similar hospital experiences. SCI distribution was 12.7% "3MS Only" (n = 42), 11.5% "Hospital Record Only" (n = 38), 9.4% "Both" (n = 31), and "No CI" (n = 219). Males were more likely to be identified with CI using the "3MS Only" and "Both," and females were more likely to have no indication of CI. Conclusion: There were sex differences in the documentation of CI versus observed impairment. Males had more CI using direct testing. This may be contributing to sex differences in recovery outcomes after hip fracture. Results support the implementation of cognitive testing in hip fracture patients to reduce the impact of differential misclassification by patient sex. [ABSTRACT FROM AUTHOR]

Published
2022
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18. Selection Bias, Orthopaedic Style

Author

Pellegrini, Vincent D., primary, Eikelboom, John, additional, McCollister Evarts, C., additional, Franklin, Patricia D., additional, Goldhaber, Samuel Z., additional, Iorio, Richard, additional, Lambourne, Carol A., additional, Magaziner, Jay S., additional, and Magder, Laurence S., additional

Published
2019
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23. Own the Fall: AOA Critical Issues.

Author

Anderson, Paul A., Magaziner, Jay S., Mendelson, Daniel Ari, and Switzer, Julie A.

Subjects
*OLDER patients, *MEDICATION reconciliation, *HIP fractures, *COMORBIDITY, *HOSPITAL emergency services
Abstract

Abstract: Falls are the most common cause of injury to older patients, resulting in >3 million emergency room visits per year and 290,000 hip fractures annually in the United States. Orthopaedic surgeons care for the majority of these patients; however, they are rarely involved in the assessment of fall risk and providing prevention strategies. Falls also occur perioperatively (e.g., in patients with arthritis and those undergoing arthroplasty). Preoperatively, up to 40% of patients awaiting joint arthroplasty sustain a fall, and 20% to 40% have a fall postoperatively. Risk factors for falls include intrinsic factors such as age and comorbidities that are not modifiable as well as extrinsic factors, including medication reconciliation, improvement in the environment, and the management of modifiable comorbidities that can be optimized. Simple in-office fall assessment tools are available that can be adapted for the orthopaedic practice and be used to identify patients who would benefit from rehabilitation. Orthopaedic surgeons should incorporate these strategies to improve care and to reduce fall risk and associated adverse events. [ABSTRACT FROM AUTHOR]

Published
2021
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26. Research Priorities to Advance the Health and Health Care of Older Adults with Multiple Chronic Conditions

Author

Tisminetzky, Mayra, primary, Bayliss, Elizabeth A., additional, Magaziner, Jay S., additional, Allore, Heather G., additional, Anzuoni, Kathryn, additional, Boyd, Cynthia M., additional, Gill, Thomas M., additional, Go, Alan S., additional, Greenspan, Susan L., additional, Hanson, Leah R., additional, Hornbrook, Mark C., additional, Kitzman, Dalane W., additional, Larson, Eric B., additional, Naylor, Mary D., additional, Shirley, Benjamin E., additional, Tai‐Seale, Ming, additional, Teri, Linda, additional, Tinetti, Mary E., additional, Whitson, Heather E., additional, and Gurwitz, Jerry H., additional

Published
2017
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28. Subgroup Variations in Bone Mineral Density Response to Zoledronic Acid After Hip Fracture

Author

Magaziner, Jay S, primary, Orwig, Denise L, additional, Lyles, Kenneth W, additional, Nordsletten, Lars, additional, Boonen, Steven, additional, Adachi, Jonathan D, additional, Recknor, Chris, additional, Colón‐Emeric, Cathleen S, additional, Mesenbrink, Peter, additional, Bucci‐Rechtweg, Christina, additional, Su, Guoqin, additional, Johnson, Rasheeda, additional, and Pieper, Carl F, additional

Published
2014
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29. Antifracture Efficacy and Reduction of Mortality in Relation to Timing of the First Dose of Zoledronic Acid After Hip Fracture

Author

Eriksen, Erik Fink, primary, Lyles, Kenneth W, additional, Colón-Emeric, Cathleen S, additional, Pieper, Carl F, additional, Magaziner, Jay S, additional, Adachi, Jonathan D, additional, Hyldstrup, Lars, additional, Recknor, Chris, additional, Nordsletten, Lars, additional, Lavecchia, Catherine, additional, Hu, Huilin, additional, Boonen, Steven, additional, and Mesenbrink, Peter, additional

Published
2009
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31. Recruitment of Long‐Term Care Facilities for Research

Author

Palumbo, Francis B., Magaziner, Jay S., Tenney, James H., Goren, Leslye M., and Warren, John W.

Abstract

We report the successful recruitment of a stratified random sample of nursing homes in the state of Maryland into three research studies funded by the National Institute on Aging. These studies examine the prevalence of infections and urinary tract instrumentation and the incidence of antimicrobial use in nursing home residents. Following selection of a facility, the administrator was telephoned and a meeting at the home was requested. At this meeting, the project was explained in detail using a packet of promotional information which included a project summary, a listing of project staff and their qualifications, and letters of support from influential organizations. A total of 61 eligible facilities were contacted in order to achieve a group of 53 participating homes with approximately 5000 beds. One hundred percent cooperation was achieved from all strata except small (≤50 beds) proprietary comprehensive care facilities, and homes with both comprehensive and domiciliary beds. A direct, personal approach, backed by carefully prepared study information and the support of medical and nursing home organizations resulted in successful recruitment of 53 (87%) of 61 homes sampled.

Published
1987
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32. Advancing Clinical Trials in Nursing Homes: A Proposed Roadmap to Success.

Author

Gurwitz JH, Quinn CC, Abi-Elias IH, Adams AS, Bartel R, Bonner A, Boxer R, Delude C, Gifford D, Hanson B, Ito K, Jain P, Magaziner JS, Mazor KM, Mitchell SL, Mody L, Nace D, Ouslander J, Reifsnyder JA, Resnick B, and Zimmerman S

Subjects
Aged, COVID-19 epidemiology, Female, Humans, Male, Pandemics, SARS-CoV-2, United States epidemiology, Clinical Trials as Topic organization & administration, Nursing Homes organization & administration
Abstract

An effective clinical research effort in nursing homes to address prevention and treatment of COVID-19 faced overwhelming challenges. Under the Health Care Systems Research Network-Older Americans Independence Centers AGING Initiative, a multidisciplinary Stakeholder Advisory Panel was convened to develop recommendations to improve the capability of the clinical research enterprise in US nursing homes. The Panel considered the nursing home as a setting for clinical trials, reviewed the current state of clinical trials in nursing homes, and ultimately developed recommendations for the establishment of a nursing home clinical trials research network that would be centrally supported and administered. This report summarizes the Panel's recommendations, which were developed in alignment with the following core principles: build on available research infrastructure where appropriate; leverage existing productive partnerships of researchers with groups of nursing homes and nursing home corporations; encompass both efficacy and effectiveness clinical trials; be responsive to a broad range of stakeholders including nursing home residents and their care partners; be relevant to an expansive range of clinical and health care delivery research questions; be able to pivot as necessary to changing research priorities and circumstances; create a pathway for industry-sponsored research as appropriate; invest in strategies to increase diversity in study populations and the research workforce; and foster the development of the next generation of nursing home researchers., (© 2022 The American Geriatrics Society.)

Published
2022
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