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Introduction A method for delivering vaporized nicotine to animals has been developed using e-cigarette devices. The present experiment was designed to measure the effects of e-cigarette nicotine on pubertal onset and development of reproductive behavior in female and male Long-Evans rats. Aim and Methods Rats received daily 10-min sessions of electronic-cigarette vaporized nicotine (5% Virginia Tobacco JUUL Pods) or room air in a whole-body exposure chamber (postnatal day 28–31). Pubertal onset was monitored daily (ie, vaginal opening in females, preputial separation in males). Two weeks later, rats were tested for sexual motivation using the partner-preference paradigm, whereby subjects were given the opportunity to approach either a sexual partner or a same-sex social partner. Four weeks later, partner preference was assessed again, 10 min after rats were re-exposed to their same prepubertal treatment. Results We found that prepubescent electronic-cigarette vaporized nicotine disrupted puberty and sexual motivation in female but not male rats. In vaped females, vaginal opening was delayed and less time was spent with the male stimulus compared to room-air controls. In contrast, no effect of e-cigarette vapor was observed on pubertal onset or on any measures of sexual behavior in male rats. No effects were observed in either female or male rats on the second partner-preference test. Conclusions Prepubescent vaporized nicotine affected the development of reproductive physiology and behavior in female rats but not in male rats, whereas an additional acute exposure to nicotine vapor had no effect in either female or male adult rats. Implications Given the prevalence of increasingly younger users, more animal research is needed to explore the effects of e-cigarette smoking on multiple developmental systems including reproductive physiology and behavior. This model could be useful in exploring multiple behavioral and physiological endpoints in both sexes. Adjustments to the duration of exposure and control conditions will be necessary for future experiments to best model human use. [ABSTRACT FROM AUTHOR]

The optimal timing of sexual behaviours across a daily cycle can form a key component of mating and reproductive success. However, few studies have explored circadian rhythms in mating behaviour within the context of sexual selection and sexual conflict. Here we characterized circadian patterns in female receptivity to mating and the frequency of male mating and courtship behaviours in freely interacting captive groups of red junglefowl, Gallus gallus , in outdoor enclosures. We showed that patterns of male sexual behaviour and female resistance to mating attempts differ between the morning and evening during a 10-day mating trial. Females progressively reduced their level of resistance to male mating attempts during the early hours of the morning and progressively increased their resistance in the evening. Males did not match their mating frequencies to female receptivity and initiated mating attempts more often in the evening, but tended to perform more courtship displays in the morning. The pattern of male behaviour was associated with social status, such that dominant males courted females more often than subordinates, particularly in the morning. However, we did not find strong evidence that male social status was associated with different timing strategies. These results demonstrate circadian patterns in multiple sexual behaviours in red junglefowl, with potential consequences for sexual selection in this species and welfare management in domestic populations of closely related fowl. • Sexual selection may target individual variation in circadian behaviour. • Sex differences in the optimal timing of behaviours can drive sexual conflict. • We quantified circadian patterns in sexual behaviour in a polygynandrous bird. • Males courted more in the morning and female resistance was highest in the evening. • Male social status was not associated with different timing strategies. [ABSTRACT FROM AUTHOR]

HIV transmission remains a significant health concern for men who have sex with men (MSM) in the United States. Heavy episodic drinking (HED) is related to increased rates of condomless anal intercourse (CAI) among MSM, though evidence suggests that this association may vary by individual difference factors. The present secondary analysis tested whether sexual alcohol expectancies (SAEs) moderate the associations between frequency of HED and anal intercourse (AI) with and without a condom among moderate-to-heavy drinking HIV- MSM. Two hundred and forty-eight moderate-to-heavy drinking MSM completed self-report questionnaires including the Sexual Behavior Questionnaire, the Modified Daily Drinking Questionnaire, and the Sexual Alcohol Expectancies Questionnaire. Negative binomial regressions indicated that SAEs moderated the association between frequency of HED and AI with a condom, but not between the frequency of HED and condomless AI (CAI). These results suggest that stronger SAEs play a role in alcohol-related sexual behavior among MSM, but do not provide evidence that SAEs are associated with increased risk for HIV transmission through CAI. • Expectancies moderate the drinking-frequency and anal-sex frequency relation. • Expectancies do not moderate relation of drinking frequency and condomless anal sex. • Expectancies related to increased riskiness are the strongest moderators. [ABSTRACT FROM AUTHOR]

This study conducts a systematic review of the current scientific research framework on LGBTIQ tourism and suggests new directions for its evolution. Through bibliometric analysis, content analysis, and systematic quantitative literature review, 146 articles from WoS and Scopus databases (1993–2023) were examined. Five research areas were identified: gay male sexual behaviors on holidays, discriminatory activities and attitudes, LGBT tourists’ identities, LGBTQIA events, and LGBTQ spaces. Existing literature mainly focuses on demand dynamics, specifically on gay tourists, their profiles, motivations, and experiences of discrimination. The article proposes future research directions to broaden and deepen the field of LGBTIQ tourism studies. [ABSTRACT FROM AUTHOR]

In many animals, drastic changes are observed during sexual maturation characterized by the reproductive system development concomitantly to the sexual behavior ontogenesis. These modifications are under the control of internal and external factors such as food. Sexual maturation requires considerable energetic investment, and diet has been shown to affect reproductive activities in many taxonomic groups, especially in insects and vertebrates. By contrast, diet effects on sexual behavior development remain largely unexplored. To elucidate this aspect, we used the male moth Agrotis ipsilon which undergoes sexual maturation occurring between the third and the fifth day postemergence. During this period, males are sensitive to female sex pheromones and a stereotypical sexual behavior characterized by female‐oriented flight takes place. In our study, we compared (1) sex pheromone detection by electroantennography recordings and (2) behavioral response in wind tunnel assays between males fed with different diets found in nature. Compared to standard sucrose diet, males fed with sucrose, fructose, and glucose supplemented with sodium (a mineral element necessary for the locomotor activity in several moths) did not respond better to female sex pheromones but clearly exhibited an earlier behavioral response. Thus, such a diet accelerates the development of sex pheromone‐mediated oriented flight, probably by facilitating the central processing of sex pheromone information in male A. ipsilon moths. Our results provide new information on the influence of nutritional intake on the ontogenesis of male sexual behavior in animals. [ABSTRACT FROM AUTHOR]

The document provides a historical overview of sexology, tracing its origins in Germany in the early 20th century and its subsequent development in the United States. It highlights key figures, institutions, and events that shaped the field, emphasizing the interdisciplinary approach and advocacy for sexual reform. The text also discusses the impact of societal shifts, the role of Jewish sexologists, and the resurgence of sexology in the United States post-World War II. Additionally, it explores the field's evolution towards sexual health, rights, and pleasure, culminating in the issuance of declarations and collaborations with organizations like the WHO. The document concludes by addressing current challenges and the importance of advocacy efforts to advance sexual health and rights globally. [Extracted from the article]

Rationale: Alcohol can disrupt conditioned sexual inhibition (CSI) established by first-order conditioning in male rats. CSI can also be induced using second-order conditioning, during which male rats are trained to associate a neutral odor with a nonreceptive female. As a result, when given access to two receptive females (one scented and one unscented) during a copulatory preference test, they display CSI toward the scented female. Objective: The present study examined the effect of low-to-moderate doses of alcohol on CSI and brain activation following exposure to alcohol and the olfactory cue alone. Methods: Sexually-naïve Long-Evans rats received alternate conditioning sessions with unscented receptive or scented (almond extract) non-receptive females. Following the conditioning phase, males were injected with saline, alcohol 0.5 g/kg or 1 g/kg, 45 min before a copulatory test with two receptive females, with one bearing the olfactory cue. Fos activation was later assessed, following exposure to alcohol and the olfactory cue alone, in several brain regions involved in the expression and regulation of male sexual behavior. Results: While males in the saline group displayed sexual avoidance towards the scented female, those injected with alcohol before the copulatory test, regardless of the dose, copulated indiscriminately with both females. Subsequent exposure to alcohol and the olfactory cue alone induced different Fos expression between groups in several brain regions. Conclusions: Low to moderate doses of alcohol disrupt conditioned sexual inhibition in male rats and induce a differential pattern of neural activation, particularly in regions involved in the expression and regulation of sexual behavior. [ABSTRACT FROM AUTHOR]

The purpose of the present study was to report on a pilot study using a personality-based classification of a community-based sample of 298 adolescent males with harmful sexual behaviours (AHSB) using the Millon Adolescent Clinical Inventory (MACI). Three personality-based profile types were identified using cluster analysis: Cluster 1. Detached, a detached and socially isolated type (n = 97); Cluster 2. Offending Supportive, an antisocial, offending-supportive type (n = 73); and Cluster 3. Typical Teen/Restricted, a type with few clinically elevated personality characteristics (n = 128). Further analyses indicated significant differences among the personality-based profiles on the MACI subscales that measured response styles, adolescents' concerns and clinical problems. Few statistically significant relationships between the profile types and AHSB, offence and victim characteristics were found. The clinical implications of these findings are discussed, and the need for further research on the use of personality-based classification is recommended. [ABSTRACT FROM AUTHOR]

Background. In Latin American countries and Suriname, sexual transmission is one of the most common modes of HIV transmission, and men who have sex with men (MSM) who engage in sex work constitute a key population. Methods. In a sample of MSM (N = 53,166) from the Latin American Internet Survey (2018) across 18 countries, we examined how sex work engagement is associated with syndemic conditions (multidrug use, homophobic abuse, depression/anxiety, alcohol dependency (CAGE alcohol questionnaire) and internalised homonegativity) and condomless anal intercourse with non-steady male partners using separate logistic regressions. We then used a structural equation model to determine if and how syndemic conditions mediate the relationship between sex work engagement and non-steady male partners. Results. We found that getting paid for sex was associated with less condom use for anal intercourse with non-steady male partners and particular syndemic conditions, such as multidrug use, homophobic abuse and alcohol dependency. In our structural equation model, the results showed that the direct relationship between sex work engagement and non-steady male partners was positive and significant, and syndemic conditions partially mediated this relationship. Conclusion. Our results highlight the continuing need for including MSM who engage in sex work and those who experience syndemic conditions in the prevention strategies targeted to MSM in Latin America and Suriname, to prevent the transmission of HIV. [ABSTRACT FROM AUTHOR]

This article discusses the impact of haemophilia symptoms on sexual functioning and health-related quality of life (HRQOL) in men with haemophilia. The study found that pain, the risk of bleeding, and loss of joint movement can restrict sexual activity in men with haemophilia. These restrictions in sexual functioning were associated with lower scores on HRQOL domains such as physical functioning and satisfaction with participation in social roles. The study also highlighted the lack of discussions about sexual functioning between men with haemophilia and healthcare professionals during outpatient visits. The authors emphasize the importance of addressing sexual functioning in clinical care and providing appropriate interventions for men with haemophilia. [Extracted from the article]

Introduction: Breast cancer remains the most prevalent cancer among women, with its incidence rising globally. Post-mastectomy survivors often face significant psychosexual challenges impacting their quality of life. This study investigates the psychosexual disturbances experienced by post-mastectomy women and their male partners, aiming to highlight these issues and propose suitable interventions. Methods: This cross-sectional, open-ended questionnaire study was conducted over two months with 50 post-mastectomy women and their male partners from a hospital-based setting. Participants were assessed for psychological effects, sexual disturbances, and emotional involvement through detailed questionnaires. Data were analyzed using SPSS software and represented through numerical and graphical formats. Results: The study revealed that 70% of women experienced significant psychological disturbances, including disturbed sleep patterns, depression, and a loss of self-worth. Sexual dysfunction was prominent, with reduced sexual desire, lubrication issues, and dyspareunia reported by 70% of participants. Psychological distress was more pronounced in women under 45 years. Male partners exhibited fewer disturbances, but some reported issues with sexual desire and comfort, particularly in younger age groups. Emotional involvement decreased in younger women, with increased domestic friction noted. Discussion: The findings underscore a high prevalence of psychosexual issues among post-mastectomy women and their partners, with significant age-related variations. Psychological and sexual problems are considerable and multifaceted, impacting overall quality of life. The need for comprehensive pre-and post-surgery counseling is emphasized to address these challenges effectively. Conclusion: Psychosexual morbidity is prevalent among breast cancer survivors and their partners, with notable impacts on sexual function and emotional well-being. Effective intervention strategies, including multidisciplinary sexual counseling, are essential to improve the quality of life for these individuals. [ABSTRACT FROM AUTHOR]

HIV-positive men who have sex with men (MSM) are at high risk of suicide and experience intersectional inequalities. The Social Determinants of Health (SDH) framework provides valuable insights into how inequalities can lead to adverse outcomes. This study aimed to employ the SDH framework to identify factors that contribute to suicidal behaviors among this population. 1410 HIV-positive MSM were recruited using a web-based questionnaire, whose mean age was 30.77 ± 6.92 years old. Participants completed questionnaires including baseline information and psychological measurements, such as Suicidal Behaviors Questionnaire-Revised (SBQ-R). Logistic regression analysis was conducted to screen for risk factors associated with suicidal behaviors. More than half of the participants (53.3 %, 752/1410) had an SBQ score of 7 or higher. Binary logistic regression analysis of structural and intermediary determinants (Model 3) revealed that sexual orientation, stigma (ORs: 1.018, 95 % CI: 1.005–1.032), interpersonal needs (ORs: 1.021, 95 % CI: 1.010–1.031), depression (ORs: 1.037, 95 % CI: 1.001–1.074) and entrapment (ORs: 1.018, 95 % CI: 1.004–1.032) were positively correlated with suicidal behaviors. Individuals with other or unknown sexual orientation had significantly higher rates of suicidal behaviors compared to those with a heterosexual sexual orientation (ORs: 5.021, 95 % CI: 1.529–17.640). Sampling of HIV-positive MSM posed challenges in data collection. It may introduce selection bias and affect generalizability. This study identified that sexual orientation, stigma, interpersonal needs, depression, and entrapment were significantly associated with suicidal behaviors among HIV-positive MSM. Additionally, these factors can be social determinants of health that contribute to suicidal behaviors. • This study is the first to apply the SDH framework in HIV-positive MSM. • SBQ scale rather than one or a few questions was used to measure the suicidal behaviors among HIV-positive MSM. • Sexual orientation, stigma, interpersonal needs, depression, entrapment contribute to suicidal behaviors in HIV-positive MSM. [ABSTRACT FROM AUTHOR]

The present study aimed to identify novel biostimulatory compounds in boar seminal gel (SG), saliva and semen using Gas chromatography-mass spectrometry (GC-MS). The bio-stimulatory effect of SG, SG + saliva and SG + semen on young boar for semen collection as well were employed to study bio-stimulatory effects on gilts and sows. Distilled water (DW) exposure was kept as control. SG, saliva and semen were screened for total 105, 96 and 89 compounds. The highest concentration was of alkanes followed by sugar alcohols, then hydrocarbons, amino acids and fatty acids. Elaidic acid was the novel compound identified in pigs. Significantly higher (p < 0.05) number of males got trained in exposure to SG (80%), SG + saliva (75%) and SG + semen (75%) than control (0%). The time (hrs) taken by young boars to get trained on exposure to combination of SG + saliva (244 ± 22.19) and SG + semen (216 ± 13.14) was lesser (p < 0.05) than SG (356 ± 61.85) alone. Interval (hrs) from initiation of exposure for exhibition of different sexual behaviour by males on exposure to SG, saliva and semen was lesser (p < 0.05) than control. Significantly (p < 0.05) higher number of females showed estrus response to exposure of SG (72.72%), SG + saliva (69.23%) and SG + semen (76.92%) than control (0). Interval (hrs) taken to exhibit estrus was shorter (p < 0.05) in females exposed to SG + saliva (201.88 ± 12.66), SG + semen (198.20 ± 9.42) than SG (262.14 ± 20.06) alone. Interval (hrs) for exhibition of different sexual behaviour by females on exposure to SG + saliva and SG + semen was lesser (p < 0.05) than control. In conclusion, novel compounds were identified in boar seminal gel, saliva and semen with biostimulatory properties have been identified in boar SG, saliva and semen. The combined exposure of SG with saliva and semen has more intense biostimulation effect than SG alone for training of young boars and estrus induction in gilts and sows. Such compounds biostimulatory effects can be exploited for augmenting reproductive efficiency in pigs. [ABSTRACT FROM AUTHOR]

The article discusses the Hindi comedy film OMG 2, which explores the challenges faced by a young boy in India regarding his sexual identity and experiences. It highlights the lack of comprehensive sex education for young boys and the role of media in filling this gap. The article emphasizes the need to include boys in discussions of sex education and challenges the stereotypes and misconceptions surrounding masculinity. It also discusses the limitations of traditional sex education methods and suggests that media platforms can be effective tools for spreading awareness and providing accurate information about sex and sexuality. [Extracted from the article]

Most theories predict, and most studies demonstrate, that men have a higher sex drive than women do. A spirited debate has emerged surrounding the origins of gender differences in sex drive; Frankenbach et al. (2022) commented on this controversy in the context of their impressive meta-analysis. We provide a different interpretation of these findings: Specifically, women get worse sex than men do. We argue that if the differences between the sex that women get and the sex that men get were accounted for, gender differences in sex drive would be reduced or eliminated completely. We focus more specifically on two factors that should be accounted for in future meta-analyses—narrow definitions of "sex" as penile–vaginal intercourse, and gender disparities in sexual violence—and additional factors that should be acknowledged when interpreting meta-analytic results—gendered cultural messages, respect from heterosexual partners, and sexual stigmatization. Public Significance Statement: Most research finds that men have a somewhat higher sex drive than women do, when sex is defined vaguely. We address potential reasons for the difference: Women and men may be driven toward different types of sex, women experience substantially more sexual violence than men, messages from society are more permissive and positive toward men's sexuality than women's, heterosexual women are more likely to be disrespected by their partners than heterosexual men, and women are stigmatized for wanting sex. [ABSTRACT FROM AUTHOR]

Research on the use of sex toys has been primarily performed from a medical perspective, while there is still limited research from a psychosocial perspective. To bridge this gap, in this study we examined whether some psychosocial variables might be linked to sex toy ownership in a sample of 3960 Italian (cisgender men and women) sex toy buyers. More specifically, we investigated the association between gender identities and ideologies and the variety and types of sex toys owned. Based on the data, we detected two dimensions underlying the ownership of sex toys: (1) orientation to owning kinky sex toys and (2) orientation to owning clit-oriented sex toys. Results showed that benevolent sexism and gender system justification were negatively correlated with owning clit-oriented toys. Moreover, strongly gender-identified participants owned a small variety of different toys and preferred toys that were designed to stimulate the vagina or clitoris over less commonly-used toys. No significant correlation between feminist identification and sex toy type owned was found when gender identification was taken into account. These results suggest that the owning of sex toys might be associated with traditional gender ideology and the strength of gender identification. [ABSTRACT FROM AUTHOR]

Feminist considerations have influenced how women and men view sex, affecting not only women's perspectives but also men's feelings about sexual desire with regard to gender equity. This might be especially the case among men who self-identify as feminist. However, how men should manage their sexual desire or communicate about it within relationships with women is not always clear in this evolving social climate. Thus, the current study aimed to explore the successes and/or struggles feminist heterosexual men experience while navigating their desires alongside feminist considerations. To explore this, we recruited feminist-identified heterosexual men in long-term relationships. We asked participants (N = 30) a series of questions regarding their sexual desire, considering the context of their long-term relationships and evolving gender norms, during a one-on-one interview via Zoom. Using thematic analysis, we identified 11 themes from the interview data. We found that, though the feminist men in this study were all aware of negative societal perceptions of heterosexual men's sexual desire, most men in this study did not feel conflicts between their feminist principles and their own sexual desires. This is because they reported already following feminist principles; those who felt ambivalent navigated this by communicating with their partners. Findings demonstrate the usefulness and positive impact men report feminism having on them, their sexuality, and their long-term relationships, by allowing them to better engage with their sexuality and partners. [ABSTRACT FROM AUTHOR]

Sociosexuality refers to the tendency to engage in uncommitted sexual behavior and has been dissected into three domains: sociosexual behavior, attitudes, and desire (Penke & Asendorpf, 2008), which led to the revised Sociosexual Orientation Inventory (SOI-R), which was validated on a German sample. The current research aimed at translating and validating an Italian version (I-SOI-R), administered to three distinct Italian participant groups. In the first sample (N = 710, females = 521, age = 18–59 years), we found evidence for a bifactor model, articulated in a general sociosexuality factor and three specific factors (behavior, attitudes, desire). High internal consistency was established for total and subscale scores, alongside favorable test–retest reliability. A connection was found between relationship status and sociosexual desire, though not gender dependent. We found evidence for test–retest reliability in a second sample (N = 55, females = 37, age 20–58 years). In a third study (N = 305, females = 147, age = 19–60 years), the earlier findings were replicated, further confirming the I-SOI-R's construct, criterion, and nomological validity on an online sample. Combining data from the three studies revealed full configural, metric, and scalar invariance regarding gender. This allowed us to meaningfully compare the observed scores of women and men and replicated the finding that men display higher levels of unrestricted sociosexuality. In conclusion, the I-SOI-R may serve as a valuable tool to assess and enhance sexual health, albeit warranting future research on construct and criterion validity. [ABSTRACT FROM AUTHOR]

The article examines historical medical injustices against sexual and gender minority groups, focusing on the pathologization of homosexuality and gender nonconformity. It covers early medical references and stigmatizing diagnoses, as well as harmful treatments like conversion therapy and institutionalization. It sheds light on the lasting impact of these practices on Lesbian, Gay, Bisexual, Transgender, and Queer/Questioning (LGBTQ)+ individuals.

Oyster peptide (OP) and Pfaffia glomerata extract (PGE) were used as raw materials. The optimal formulation of the pressed candy (PC) was optimized by one‐way experiment and D‐optimal mixture experiment design, and animal experiment was used to evaluate the effect of PC on male sexual dysfunction. The results showed that PC intervention significantly improved the sexual behavior of male mice with sexual dysfunction, including a significant shortening of the mount latency (ML) and intromission latency, and a significant increase in the mount frequency (MF) and intromission frequency (IF). At the same time, the concentrations of serum testosterone (T) and luteinizing hormone (LH) in mice were restored, and the erectile parameters and pathological changes of penile tissue were improved. Further studies found that PC intervention increased the activities of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH‐Px) and reduced the content of malondialdehyde (MDA) in testicular tissue. In addition, PC intervention improved testicular tissue morphology. In conclusion, the obtained PC has good taste quality, and the relevant quality indicators are qualified. It has a good ameliorative effect on male sexual dysfunction and may be a potential dietary supplement. [ABSTRACT FROM AUTHOR]

Objectives Methods Results Conclusion The HIV/AIDS epidemic has disproportionately affected men who have sex with men (MSM) since its onset. Despite important medical advancements in treatment, the enduring effects of living with HIV continue to adversely impact the health and well‐being of this population. This cross‐sectional nationwide study examined psychosocial and sexual health among MSM in Denmark, comparing those living with and without HIV.Data from MSM living with HIV were collected from the SHARE study, a Danish nationwide survey that investigated psychosocial, sexual and reproductive health among people with HIV, and compared with data from MSM without HIV, retrieved from the nationally representative cohort study, Project SEXUS. Associations between HIV status and psychosocial and sexual health outcomes were examined using logistic regression models while controlling for potentially confounding variables.Among 369 MSM with HIV and 1002 MSM without HIV, logistic regression analyses revealed that living with HIV was significantly associated with having current symptoms of anxiety and depression and greater dissatisfaction with one's body. Additionally, MSM with HIV significantly more often than MSM without HIV reported low sexual desire, sexual inactivity, a lack of sexual needs in the last year and erectile dysfunction. Having received payment for sex was more frequently reported by MSM with HIV, as was sexualised drug use, including chemsex drugs.Compared with MSM without HIV, MSM with HIV in Denmark report a higher burden of mental health and sex life challenges. [ABSTRACT FROM AUTHOR]

Sterilization and castration have been synonyms for thousands of years. Making an animal sterile meant to render them incapable of producing offspring. Castration or the physical removal of the testes was discovered to be the most simple but reliable method for managing reproduction and sexual behavior in the male. Today, there continues to be global utilization of castration in domestic animals. More than six hundred million pigs are castrated every year, and surgical removal of testes in dogs and cats is a routine practice in veterinary medicine. However, modern biological research has extended the meaning of sterilization to include methods that spare testis removal and involve a variety of options, from chemical castration and immunocastration to various methods of vasectomy. This review begins with the history of sterilization, showing a direct link between its practice in man and animals. Then, it traces the evolution of concepts for inducing sterility, where research has overlapped with basic studies of reproductive hormones and the discovery of testicular toxicants, some of which serve as sterilizing agents in rodent pests. Finally, the most recent efforts to use the immune system and gene editing to block hormonal stimulation of testis function are discussed. As we respond to the crisis of animal overpopulation and strive for better animal welfare, these novel methods provide optimism for replacing surgical castration in some species. [ABSTRACT FROM AUTHOR]

AbstractWhen men root manhood in sexual performance, their inability to get and maintain an erection (i.e. erectile dysfunction) may pose a threat to ageing men’s ability to enact masculinity. Using data from the 2015–2016 National Social Life, Health and Aging Project (NSHAP) – a nationally representative survey of the USA – this study finds that age and erectile dysfunction interact: men who report ‘trouble getting or maintaining an erection’ have a higher odds of reporting anxiety before sex. However, this effect gradually declines as the sample of men with erectile dysfunction ages (from ages 49 to 95). Additionally, men who do not report erectile dysfunction have the same odds of sex-anxiety throughout the sample, regardless of their age. The change in sexual performance may cause distress for men, as they feel unable to maintain their dominant masculinity in old age. While previous studies have shown that age and gender interact to affect men’s sexual health in mid-life and later-life, this study adds to the feminist gerontology literature by providing indirect evidence that changes in sexual response may become gradually less anxiety-inducing, and thereby, less threatening for men as they age. [ABSTRACT FROM AUTHOR]

AbstractDespite growing understanding and acceptance of the concept of Undetectable = Untransmittable (U = U) among gay men, HIV stigma remains a burden for people living with HIV. This study explored perceptions of HIV among HIV seronegative gay men in Sweden in this new context. Using snowball sampling, 15 gay men born between 1980 and 2000 were recruited to the study. Semi-structured interviews were conducted and data were subjected to reflexive thematic analysis. Men grew up experiencing gay stigma and were repeatedly informed by parents, schools, communities, peers, and popular culture about the dangers of HIV, and that gay men were a high-risk group. As men grew older, and the premise of HIV shifted dramatically due to U = U, some remained emotionally anchored to the pre-U = U era, while others realigned their perceptions, often after a process of reconciling emotional responses (e.g. HIV = death) with the logical-rational claims made about U = U. The study highlights key areas for future efforts, namely establishing a balance between HIV education strategies and stigma reduction initiatives. Study findings underscore the need to care for the memory of those lost during the crisis years, while also addressing the stigma faced by those currently living with HIV. [ABSTRACT FROM AUTHOR]

Due to the high reproductive investment, females are the decisive sex when making decisions about whether or not to reproduce. Generally, female scorpions display aggressive sexual behavior in response to male reproductive advances when they are not receptive. However, female receptivity can vary over time, depending on environmental factors favorable to reproduction Thus, the current study aimed to examine the correlation between the number of reproductive attempts by male Tityus pusillus scorpion and mating success over time, considering the female's behavioral response. Behavioral analyses were monthly conducted on 150 T. pusillus field-caught pairs over a five-month period. Our results indicate that despite females reacting aggressively to male advances, the persistence of the male has a positive effect in courtship probability. Furthermore, we observed variations in female behavior throughout the studied period, suggesting that female receptivity might be linked to the reproductive season. Therefore, environmental factors may play a significant role in regulating scorpion reproduction in Neotropical forests. [ABSTRACT FROM AUTHOR]

While rare in the larger population, anal cancer incidence is significantly higher in groups such as sexual minority men and people living with HIV. This qualitative analysis examined participants' experiences and perceptions of barriers to anal self-examination and anal companion examination through interviews completed as a part of a larger clinical trial. Interviews were conducted online with participants (n = 131) within a week of their baseline appointment between January 2020 and October 2021. Content analysis denoted participants' thoughts and perceptions about anal self-examination and anal companion examinations. Of the 131 cisgender men interviewed (mean age 49.9 years, SD 12.7), 92.4% identified as gay, 54.9% identified as white, 22.1% identified as Black, 19.9% identified as Latino, and 44.3% of participants were living with HIV. Participants did not report feelings of excessive anxiety when an abnormality was detected. However, three salient themes emerged as to why participants may not perform an anal self-examination or anal companion examination: (1) physical limitation(s), (2) potential sexualisation of the examination, and (3) level of comfort discussing anal health. Future work must continue to explore methods that not only decrease stigma surrounding anal health but also bolster feelings of accessibility to perform self and couple examinations. [ABSTRACT FROM AUTHOR]

This article, published in Marine Mammal Science, describes a rare observation of potential altruistic behavior by a male northern elephant seal. Altruism, the act of assisting another in need, is commonly seen in social birds and mammals, but male altruism is rarely observed in marine mammals. The researchers document an incident where an adult male elephant seal responded to a distressed pup and helped it return to shore, despite the potential cost to his own survival and reproduction. The authors speculate that kin selection and the low harem density at the colony may have contributed to this behavior. Further research is needed to understand the development of altruistic traits in marine mammals. [Extracted from the article]

Background: Illicit drug and high-risk alcohol use among adolescents leads to poor health outcomes. We enrolled adolescents from urban slums in Kampala, Uganda, to assess baseline prevalence and factors associated with illicit drug and high-risk alcohol consumption. Methods: We conducted a cross-sectional study using data collected in a cohort that enrolled 14-19-year-old male and female participants from 25 March 2019 to 30 March 2020. Data was collected on social demographics, sexual behavior, and reproductive health using interviewer-administered questionnaires. The main outcomes were illicit drug use and high-risk alcohol use. Data on alcohol use was collected using the Alcohol Use Disorder Identification Test (AUDIT); results were dichotomized. Factors associated with each outcome were analyzed using multivariable logistic regression. Results: We enrolled 490 participants (60.6% female) with a median age of 18 (IQR 17–18) years, 84.9% had less than secondary education, 48.4% had their sexual debut before 15 years, 47.1% reported paid sex in the past 3 months and 22.8% had a sexually transmitted infection (chlamydia, gonorrhea, and active syphilis) baseline characteristics associated with illicit drug use in the past 3 months were male gender (aOR 12.45; 95% CI 7.21–21.50) being married (aOR 2.26; 95%CI 1.03–4.94) 10 or more paying sexual partners (aOR 2.45; 95%CI 1.05–5.69) and high-risk alcohol use (aOR 3.94; 95%CI 2.10–7.40), baseline characteristics associated with high-risk alcohol use were male gender (aOR 0.29; 95% CI 0.13–0.63) emotional violence from sexual partners (aOR 2.35; 95%CI 1.32–418) illicit drug users com (aOR 3.94; 95% CI 2.10–7.40). Conclusion: Illicit drug and high-risk alcohol use are prevalent among male adolescents and adolescents involved in high-risk sexual behavior living in the urban slums of Kampala. [ABSTRACT FROM AUTHOR]

Introduction: Gender incongruence (GI) is characterized by a marked incongruence between an individual's experienced/expressed gender and the assigned sex at birth. It includes strong displeasure about his or her sexual anatomy and secondary sex characteristics. In some people, this condition produces a strong distress with anxiety and depression named gender dysphoria (GD). This condition appears to be associated with genetic, epigenetics, hormonal as well as social factors. Given that L-glutamate is the major excitatory neurotransmitter in the central nervous system, also associated with male sexual behavior as well as depression, we aimed to determine whether metabotropic glutamate receptors are involved in GD. Methods: We analyzed 74 single nucleotide polymorphisms located at the metabotropic glutamate receptors (mGluR1, mGluR3, mGluR4, mGluR5, mGluR7 and mGluR8) in 94 transgender versus 94 cisgender people. The allele and genotype frequencies were analyzed by c2 test contrasting male and female cisgender and transgender populations. The strength of the associations was measured by binary logistic regression, estimating the odds ratio (OR) for each genotype. Measurement of linkage disequilibrium, and subsequent measurement of haplotype frequencies were also performed considering three levels of significance: P = 0.05, P = 0.005 and P = 0.0005. Furthermore, false positives were controlled with the Bonferroni correction (P = 0.05/74 = 0.00067). Results: After analysis of allele and genotypic frequencies, we found twenty-five polymorphisms with significant differences at level P = 0.05, five at P = 0.005 and two at P = 0.0005. Furthermore, the only two polymorphisms (rs9838094 and rs1818033) that passed the Bonferroni correction were both related to the metabotropic glutamate receptor 7 (mGluR7) and showed significant differences for multiple patterns of inheritance. Moreover, the haplotype T/G [OR=0.34 (0.19-0.62); P<0.0004] had a lower representation in the transgender population than in the cisgender population, with no evidence of sex cross-interaction. Conclusion: We provide genetic evidence that the mGluR7, and therefore glutamatergic neurotransmission, may be involved in GI and GD. [ABSTRACT FROM AUTHOR]

Sexual concerns after prostate cancer (PCa) treatment are high. Flexible coping is a crucial element to maintaining sexual activity after PCa and improves adaptation outcomes. We aimed to identify potential sexual adaptation styles reported by men following PCa treatment, and to assess relationships among associated variables and outcomes. Individuals (n = 223) with PCa treatment history (e.g., radical prostatectomy [n = 165, 74.0%], external beam radiation [n = 83, 37.2%], hormone/androgen deprivation therapy [n = 83, 37.2%]), completed an online survey assessing sexual variables and processes of sexual adaptation. Using a combination of inductive and deductive coding, open-ended responses were thematically analyzed and grouped into sexual adaptation styles. Factors potentially associated with sexual adaptation styles (e.g., age, perceived partner involvement, co-morbidities, relationship duration, time since PCa treatment, desire for physical affection, depression, relationship adjustment) were tested using multinomial logistic regression. Outcomes of sexual well-being (sexual distress, sexual bother, sexual satisfaction) and relationship adjustment were compared against each sexual adaptation style using a multivariate analysis of variance. Sexual activity status and satisfaction with the adaptation process was assessed across the sexual adaptation styles using a chi-square analysis and post-hoc tests. Two distinct categories were identified: those who had Adapted (n = 185) and those who had Not Adapted (n = 38). Four sexual adaptation styles emerged in the adapted category: Relationship Renegotiation (n = 53) and Sexual Renegotiation (n = 47), which were couples-focused styles, and Acceptance/Resignation (n = 34) and Masturbation/Erection (n = 48), which were individual-focused styles. Participants who could not be categorized as one style, but rather met several, were identified as Mixed (n = 3). Higher rates of depression, lower relationship adjustment, lack of sexual activity, and greater dissatisfaction with the adaptation process were observed for Not Adapted participants. Participants engaged in any type of adaptation style fared better than those who had Not Adapted. Couples-focused styles tended to emphasize renegotiation, including a changed perspective on the expression of the relationship. Perceived direct engagement of the partner facilitated adaptation and emphasized engagement with flexible coping, either through redefining priorities or ways of being sexual. Individual-focused styles emphasized pre-cancer erectile function, and either aimed to return to capacity for penetrative sexual activity or accepted its inaccessibility and largely an abandonment of partnered sexual activity. [ABSTRACT FROM AUTHOR]

Assessing another person's intention to flirt and, relatedly, their sexual interest is based on the interpretation and weighting of global (e.g., clothing style) and specific (e.g., facial expression) cues. Since cue incongruency increases the risk of erroneous judgments and thus can entail undesirable outcomes for both parties involved, detection of an individual propensity for overly relying on global (sexual) rather than specific (affective) cues is of social and clinical-forensic importance. Using a purpose-designed and pre-validated stimulus set, we developed a mouse-tracking task as an indirect behavioral measure for males' overreliance on global cues (OGC) in the context of sexual flirting. In a convenience sample of heterosexual cisgender men (N = 79), experimentally induced sexual arousal was shown to increase the probability of OGC as a function of task difficulty (i.e., congruent or incongruent combinations of global and specific cues displayed by a potential female flirting partner). While error rate and reaction time proved to be indicators of OGC, the spatial measures maximum deviation and area under the curve provided less consistent results. In addition, error rate suggested sex drive and sexual objectification to act as moderators of the relationship between sexual arousal and OGC. Exploratory analysis further revealed a theoretically meaningful pattern of correlations between mouse-tracking measures and self-report measures of problematic (e.g., disinhibited, exploitative) sexuality. Implications of the results are discussed and a framework for differentiating potential causes of OGC (i.e., misperception, lack of self-control, and egocentric hedonism) is proposed. [ABSTRACT FROM AUTHOR]

Children in their childhood and teenage years can acquire either healthy or unhealthy lifestyles. Without proper guidance, unhealthy lifestyles (e.g. risk-taking, substance abuse, poor family planning) may affect their psychosexual development negatively (i.e. the ability to make healthier sexual choices). Male and female teachers can be role models for learners to acquire healthy sexual lifestyles. Historically, the Foundation Phase (FP) has been a highly feminine teaching space. Lately, however, the space has seen an increasing presence and participation of male teachers. This paper shares FP male teachers' experiences of teaching comprehensive sexuality education (CSE) content within the Life Skills curriculum in the Eastern Cape Province of South Africa. Five FP male teachers were engaged in a focus-group conversation; data were thematically analysed, underpinned by a feminist post-structural lens. Although the teachers reported a restriction of FP male teachers in teaching of CSE-related content, they also indicated that learners showed increased self-exposure to CSE-related content. To counter the censorship of FP male teachers in teaching CSE-related content, the study recommends explicit incorporation of feminist pedagogies to enable FP male teachers to be part of the delivery of SE content as equal stakeholders. [ABSTRACT FROM AUTHOR]

The article explores the history of sexuality during the American Civil War and explains two versions of homosexuality that make meaning of the war, which are male-male intimacy and identity and deviant sexuality. It examines Civil War novels that depicted disunion between male romantic friendship to make sense of Confederate failure, as well as homoeroticism to make points about U.S. politics. It analyzes theories on the perversion of African American male sexuality.

Advances in HIV prevention tools have outpaced our ability to ensure equitable access to these tools. Novel approaches to reducing known barriers to accessing HIV prevention, such as stigma and logistical-related factors, are urgently needed. To evaluate the efficacy of a randomized controlled trial with four intervention arms to address barriers to HIV/STI testing uptake (primary outcome) and PrEP use, depression, and HIV test results (secondary outcomes). We tested a 2 × 2 research design: main effect 1—stigma-focused vs. health information evaluation–focused counseling, main effect 2—offering HIV/STI testing appointments in person vs. at home with a counselor via video chat, and the interaction of the main effects. Participants (N = 474) residing in the southeastern USA were screened and enrolled in a longitudinal trial. Intervention efficacy was established using generalized linear modeling with binomial or Poisson distributions. Intervention efficacy demonstrated an increase in HIV/STI testing uptake when testing was made available at home with a counselor via video chat vs. in person (83% vs. 75% uptake, p <.05), and participants were also more likely to test positive for HIV over the course of the study in the at-home condition (14.5% vs. 9.4%, p <.05). Stigma-focused counseling resulted in lower depression scores and greater uptake of PrEP among participants < 30 years of age when compared with health information counseling (15.4% vs. 9.6%, p <.05). In order to prevent further disparities between HIV prevention advances and access to HIV prevention tools, we must prioritize improvements in linking people to care. Novel interventions, such as those proposed here, offer a practical, evidence-based path to addressing long-standing barriers to HIV prevention strategies. Trial registration: NCT03107910. [ABSTRACT FROM AUTHOR]

The COVID-19 pandemic and subsequent mitigation measures led to social disruption and negative economic shocks for a large proportion of Uganda's population. The social and economic consequences of COVID-19 on Ugandan men's sexual behaviours, including transactional sex relationships, are unclear. We conducted in-depth interviews between November 2021–February 2022 with 26 men in a high HIV prevalence region of Uganda. Data were analysed thematically to understand how sexual relationships, including transactional sex, were impacted by COVID-19. We found that COVID-19 mitigation measures had far-reaching social and economic impacts on most respondents, particularly those employed in the informal economy. Men described experiencing job loss, food insecurity and restricted mobility, which limited opportunities to provide for and meet with transactional sex partners. Inability to provide financial resources meant that men could not form new transactional sex relationships and men who could no longer provide for their existing transactional sex partners consistently reported relationship dissolution. Men who reported stable employment during the pandemic described few changes in transactional sex relationships. Similarly, men in non-transactional relationships did not report relationship dissolution despite decreased financial provision. Further research should assess the potential short- and long-term impacts of COVID-19 mitigation measures on transactional sex relationships. [ABSTRACT FROM AUTHOR]

Curcuma longa, best known for its culinary application as the main constituent of curry powder, has shown potential impact on the reproductive system. This study aimed to investigate the efficacy of Curcuma longa extract (CLE) on Kidney‐Yang deficiency mice induced by hydrocortisone and the possible roles in testosterone secretion in Leydig cells. We evaluated male sexual behaviour, reproductive organ weight, testosterone levels, and histological tissue changes in hydrocortisone‐induced mice. CLE effectively reversed hydrocortisone‐induced Kidney‐Yang deficiency syndrome by improving sexual behaviour, testis and epididymis weight, testosterone levels and reducing pathological damage. Our in vitro study further indicated that CLE stimulated testosterone production via upregulating the mRNA and protein expression of steroidogenic enzymes in Leydig cells. It significantly improved H89‐inhibited protein expression of StAR and cAMP‐response element‐binding (CREB), as well as melatonin‐suppressed StAR protein expression. The data obtained from this study suggest that CLE could alleviate Kidney‐Yang deficiency symptoms and stimulate testosterone production by upregulating the steroidogenic pathway. This research identifies CLE as a potential nutraceutical option for addressing testosterone deficiency diseases. [ABSTRACT FROM AUTHOR]

This article provides an alternative, sexual reinterpretation of Machiavelli’s Mandragola from an alternative sexual perspective focusing on sodomy (in its sixteenth-century meaning), and especially male-male sexuality. In this reading, Messer Nicia is, put in today’s terms, a homosexual and, at the same time, surprisingly enough, the key, princely character in the play. Dri ven by a desire to establish a new, less oppressive familial order, Nicia is able to renew his corrupted family by means of a conspiracy aimed at liberating Lucrezia’s sexuality from the restraints of the dominant morality. Mandragola constitutes an intrinsic part of Machiavelli’s political project, showing how the explosion of sexual desire beyond the confines of dominant heteronormative morality can serve as a productive way of expressing plebeian desire not to be oppressed and commanded by the great, which proves beneficial to all. [ABSTRACT FROM AUTHOR]

The aim of this study is to examine how male sexuality is visually portrayed in advertisements for men's perfume and to investigate the notions of masculinity, gender, and sexuality depicted therein. Through a visual text analysis approach rooted in social semiotic theory with literature study, the study examines 27 advertisements predominantly from Western countries (Specifically France and Italy), analyzing elements such as visual composition, gendered representations, and societal implications. The analysis of the sampled images reveals stereotypical representations of male and female sexuality, conveyed through the use of sexuality and gender concepts. For male consumers, exposure to these representations may lead to the internalization of these ideals, influencing their self-image and behavior. These representations not only maintain existing power differentials but also hinder progress towards gender equality and challenging societal norms. [ABSTRACT FROM AUTHOR]

Genital self-image (GSI) involves subjective perceptions, experiences, and feelings of individuals regarding their genitalia. A negative GSI contributes to lower sexual esteem and, consequently, negative sexual experiences and sexual dysfunction. In men, self-perception may be influenced by several factors, including penis size or shape, personal experiences, body image, general health status, sex education, and even the media they consume. This study aimed to understand the reasons that lead to dissatisfaction with GSI among Brazilian men. With a mixed approach, we present male perceptions regarding dissatisfaction with GSI captured from the following question: "If you are dissatisfied with your genitals, tell us for what reason(s)? (Optional)," which integrated the last questionnaire element of the original survey. Brazilian men over 18 years of age from different Brazilian states were eligible. In this analysis, 376 responses were obtained. The data were analyzed using thematic content analysis. The participants expressed the reasons for dissatisfaction, which were grouped into two categories: (1) anatomical aspects and beliefs in the construction of GSI and (2) functional aspects. The results offer an understanding of men's perceptions of their genitals and may aid in clinical practice and research on how Brazilian men perceive their genitals. It is possible to improve knowledge about sexual health and increase positivity regarding genital perception by providing information about the reasons that lead to dissatisfaction with the genitals. [ABSTRACT FROM AUTHOR]

Rationale: Cabergoline (CAB) is an ergot derivative typically prescribed for the treatment of hyperprolactinemia. It suppresses the release of prolactin through agonist actions on dopamine (DA) D2 receptors; however, it possesses binding affinity for other DA and 5-HT receptors. Side effects that exacerbate valvular heart disease can occur with high doses. Objective: The present study examined the acute, subchronic, and chronic dose–response effects of CAB and a derivative dimethylcabergoline (DMC) which acts as an antagonist instead of agonist at 5-HT 2B receptors, on appetitive and consummatory sexual behaviors of male rats. Methods: CAB (0, 0.03, 0.15, or 0.3 mg/kg/ml) was administered daily to sexually experienced male rats (N = 10/dose) by oral gavage for a total of 68 days. Sexual behavior was tested every 4 days during this period for a total of 16 trials. On the 17th trial, rats were administered their dose of CAB, and 4 h after were overdosed with sodium pentobarbital, perfused intracardially, and their brains processed for Fos immunohistochemistry. DMC (0, 0.03, 0.15, 0.3 mg/kg/ml) was administered daily to sexually experienced male rats (N = 10/dose) by oral gavage for a total of 36 days. Sexual behavior was tested every 4 days for a total of 9 trials. Results: CAB increased anticipatory level changes, intromissions, and ejaculations significantly across all timepoints, with the medium and high doses being most potent. The medium and high doses also increased Fos protein significantly within the medial preoptic area, whereas in the nucleus accumbens shell, the low and medium doses decreased Fos protein but the high dose increased it significantly from control. Similar to CAB, the medium and high doses of DMC increased the number of ejaculations significantly. Rats in all drug dose groups appeared healthy for the duration of the experiments. Conclusions: Both CAB and DMC facilitate ejaculations, and CAB further facilitates measures of anticipatory sexual motivation and intromissions. These data suggest that both could be used as treatments for sexual arousal disorders and ejaculation/orgasm disorders with little or no untoward side effects at low doses. [ABSTRACT FROM AUTHOR]

The experiences of sexual minority men who report self-perceived problematic pornography use is under theorised and not well understood despite controversial and conflicting research into the phenomena in heterosexual male populations. This study aimed to widen the conversation to consider the experience of sexuality in relation to self-perceived problematic pornography use, rather than contribute to literature that debates the definition and aetiology of problematic pornography use. Semi-structured online qualitative interviews were conducted with three sexual minority men who self-reported problematic pornography use. Interpretive phenomenological analysis was used to develop themes. Five themes pertinent to understanding the participants' experiences with problematic pornography use were developed: problematised sexuality, pornography as liberator, pornography as corrupter, reform, and relapse and restore. The themes highlight three men's relationship with their sexuality as a feature of their self-perceived problematic pornography use. The research suggests that idiographic experiences of self-perceived problematic pornography use are influenced and maintained by an incongruent and conflicting relationship between an individual's own experiences of sexuality and self-perceptions of pornography use. Limitations and future research recommendations are discussed. [ABSTRACT FROM AUTHOR]

Men who have sex with men (MSM) is an inclusive term used to refer to phenotypic males who have insertive or receptive sex (penile-anal or penile-oral) with other phenotypic males, including people who are transgender or have other gender identities. MSM may report their sexual orientation as homosexual, bisexual, heterosexual, or something else, but this stated sexual orientation may not align with their sexual attraction or behaviors. Several health conditions disproportionately affect MSM compared with age-matched heterosexual men, including HIV infection, anal cancer, syphilis, and depression. Clinicians should use culturally sensitive questions to obtain a comprehensive sexual history and assess sexual risk. MSM should receive regular screening for HIV, hepatitis B and C, gonorrhea, chlamydia, and syphilis. Vaccinations for hepatitis A and B and human papillomavirus should be offered. MSM may benefit from preexposure prophylaxis to prevent HIV infection, postexposure prophylaxis to reduce the risk of HIV transmission, and counseling on safer sexual practices. Screening for anal cancer associated with human papillomavirus may be performed by digital anal rectal examination, although the optimal screening strategy has yet to be determined. Clinicians should also consider more frequent screenings for mental health issues in the MSM population because the rates of depression, suicide, substance use, and other psychosocial issues are higher than those of the general population. (Am Fam Physician. 2024; 109(4):324–332. Copyright © 2024 American Academy of Family Physicians.) Men who have sex with men (MSM) is an inclusive term used to refer to phenotypic males who have insertive or receptive sex (penile-anal or penile-oral) with other phenotypic males, including people who are transgender or have other gender identities. MSM may report their sexual orientation as homosexual, bisexual, heterosexual, or something else, but this stated sexual orientation may not align with their sexual attraction or behaviors. Several health conditions disproportionately affect MSM compared with age-matched heterosexual men, including HIV infection, anal cancer, syphilis, and depression. Clinicians should use culturally sensitive questions to obtain a comprehensive sexual history and assess sexual risk. MSM should receive regular screening for HIV, hepatitis B and C, gonorrhea, chlamydia, and syphilis. Vaccinations for hepatitis A and B and human papillomavirus should be offered. MSM may benefit from preexposure prophylaxis to prevent HIV infection, postexposure prophylaxis to reduce the risk of HIV transmission, and counseling on safer sexual practices. Screening for anal cancer associated with human papillomavirus may be performed by digital anal rectal examination, although the optimal screening strategy has yet to be determined. Clinicians should also consider more frequent screenings for mental health issues in the MSM population because the rates of depression, suicide, substance use, and other psychosocial issues are higher than those of the general population. [ABSTRACT FROM AUTHOR]

Extragenital warts caused by HPV types 6 and 11 are rarely reported. However, major risk factors for anogenital warts (AGW) include men who have sex with men (MSM) and Human Immunodeficiency Virus (HIV) infection. The incidence of extragenital warts among these populations has not been reported. This study presented a case report of a 33-year-old male with high-risk sexual behavior who showed symptoms of flesh-colored and hyperpigmentation papules. Furthermore, verrucous surfaces were observed at genital and extragenital. The patient had a history of using the same razor for pubic and armpit hair, bathing with a mesh scrub, and scratching the anal area. The histopathological result showed koilocytes, while polymerase chain reaction (PCR) examination for both genital and extragenital lesions confirmed HPV type 6 and 11. This represented the first reported case describing the incidence of extragenital and AGW caused by HPV types 6 and 11. The transmission of extragenital warts was facilitated through fomites autoinoculation, particularly in the immunocompromised condition induced by HIV, which was common among MSM. Extragenital warty-like lesions were considered as warts caused by HPV type 6/11, in HIV-infected persons, specifically MSM. [ABSTRACT FROM AUTHOR]

Despite research showing that many college men and women have experienced misperception of their friendliness as sexual intent, such research has focused on this type of misperception only as a correlate of men's sexual aggression. In fact, regardless of methodology used many researchers seem to suggest women do not misperceive men's sexual intent, and in some instances may actually under-perceive it. We used a hypothetical scenario to determine whether men (n = 324) and women (n = 689) college students perceived similar sexual intent from a character who is not the same gender as they are, as depicted in a story about a man and woman on a "date." Our results revealed that men and women in our sample reported similar levels of perceived sexual intent on the part of the character with a different gender as described in the scenario, even after that character clearly indicated to the partner that they "think they do not want to have sex." In addition, the perceived level of the character's sexual intent as solicited in response to this scenario design was related to sexual coercion intentions among both men and women (though it appears more strongly related among men), and these relationships remained even after controlling for other known correlates of sexual coercion (e.g., rape myth acceptance, level of sexual arousal). Implications for the study of misperception and its origins are discussed. [ABSTRACT FROM AUTHOR]

Same‐sex sexual behavior occurs in diverse animal taxa, yet its evolutionary maintenance is poorly understood as such behavior seems to be costly and does not directly increase reproductive success. We used male Tribolium castaneum beetles, which frequently engage in same‐sex copulations, to test if same‐sex sexual behavior influences future male mating behavior and reproductive success of males. Furthermore, we tested whether same‐sex sexual behavior has benefits via indirect sperm translocation. We conducted a series of mating trials demonstrating that males exposed to same‐sex behavior did not sire less offspring compared to control males that did not engage in same‐sex behavior. This suggests that same‐sex copulations did not lead to fitness costs in subsequent mating interactions. In addition, we found no evidence that indirect sperm translocation via an intermediate male occurs in T. castaneum. Taken together, these results imply that same‐sex sexual behavior in males is associated with no costs in terms of lower mating rate and reduced siring success and does not seem to entail benefits. Moreover, our data conform to the hypothesis that sexual indiscrimination is prevalent in this species, which may explain the relatively high frequency of same‐sex sexual behavior in T. castaneum. [ABSTRACT FROM AUTHOR]

Objective: Masculinities have been explored in men with testicular cancer (TC), though limited contemporary research is available on traditional masculine norms important to masculine self‐perception. The purpose of this research was to explore the discourse of TC experience in relation to masculine self‐perception. Methods: A qualitative descriptive study was conducted consisting of semi‐structured interviews with 21 men. Men were aged between 31 and 47 (Mage = 35.7). Most men were diagnosed with Stage 1 cancer (66.6%), all men had finished active treatment and time since diagnosis ranged from 17.3 to 71.8 months (M = 47.2). Independent coding was conducted by two researchers and was refined in coding meetings with authors. Themes were developed in a predominantly deductive manner, and analysis of themes was undertaken using a reflexive analysis approach. Results: Traditional masculine norms showed differing relationships to masculine self‐perception. Two main themes were identified [1] Maintained or enhanced masculine self‐perception and [2] threats to masculine self‐perception. Subthemes demonstrated that maintaining emotional control, strength and 'winning' was important to men, and reduced physical competencies (i.e., strength, sexual dysfunction, virility) challenged self‐perception. Strict adherence to traditional norms in response to threatened self‐perception related to psychological distress. Conclusion: Leveraging traditionally masculine norms such as physical strength and control and developing flexible adaptations of masculinities should be encouraged with men with TC to retain self‐perception and potentially enable better coping. Masculine self‐perception of gay/bisexual men may centre around sexual functioning, though further research is required. [ABSTRACT FROM AUTHOR]

Chronic exposure to potentially toxic elements (PTEs) such as cadmium (Cd) leads to male reproductive toxicity through the generation of oxidative stress. Spirulina Arthrospira maxima (AM) is a cyanobacterium that has been consumed since ancient times for its high nutritional value, and in recent years for its antiviral, hepatoprotective, hypoglycemic, anticancer, and antioxidant effects, among others. This study aimed to evaluate the effects of AM against the damage to reproductive health induced by Cd. A total of 48 10-week-old sexually experienced male Wistar rats were distributed in five groups (n = 8): control; vehicle (tween-water); cadmium chloride (CdCl2) 5 mg/kg; and three doses of AM (100, 200 and 400 mg/kg) + CdCl2 5 mg/kg. All treatments were orally administered once a day for 36 consecutive days. At the end, sexual behavior was evaluated, and semen, testicle, and blood samples were obtained to analyze sperm quality, enzymatic activity, and testosterone levels, respectively. Rats exposed to Cd showed a decrease in sexual behavior, as well as in the quality of reproductive health, and an increase in oxidative stress; while rats exposed simultaneously to AM + Cd showed an improvement in all this parameters. Based on our results, we believe that the mechanism by which AM exerts its effect could be attributed to the presence of phycobiliproteins. These compounds are responsible for exerting an antioxidant effect and chelating effect on elements such as Cd. [ABSTRACT FROM AUTHOR]