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642 results on '"M. Goncalves"'

2. Effects of increased levels of supplemental vitamins during the summer in a commercial artificial insemination boar stud

Author

D.W. Lugar, K.E. Harlow, J. Hundley, M. Goncalves, J. Bergstrom, and K.R. Stewart

Subjects
swine, heat stress, seasonality, semen production, vitamins, Animal culture, SF1-1100
Abstract

Heat stress due to increasing extremes in ambient temperature and humidity results in reduced semen quality in boars. This has caused reduced efficiency of the swine industry, requiring more boars to breed the same number of sows. Vitamins such as vitamin C (VC) and E (VE) have been shown to improve semen quality in boars. Recently, vitamin D has been shown to improve semen quality in boars. The purpose of this experiment was to evaluate the effects of increased supplemental vitamins on boar reproduction during the summer season in a commercial boar stud. One hundred and sixty Pig Improvement Company (PIC) terminal line boars (n = 32 per treatment) and 39 maternal, heat-sensitive boars (n = 7 or 8 per treatment) were randomly allocated to treatment and fed a corn and soybean meal-based diet adjusted based on individual boar body condition score. A control (CNT) diet was used that met PIC recommendations for boars. Increased supplementation of specific vitamins was given in the form of a top-dress and consisted of CNT wheat middlings, CNT plus VC (560 mg/day), CNT plus 25-hydroxy vitamin D3 (VD) (125 µg/day), CNT plus VE (275 mg/day) and CNT plus VC, VD and VE (CDE). The experiment was split into three periods based on maximum daily high temperatures in the barn, where period 1 was weeks 1 to 4, period 2 was weeks 5 to 11 and period 3 was weeks 12 to 14. Semen was collected from boars as needed using the stud’s normal production schedule and was analyzed for sperm quantity and quality characteristics. There were no dietary effects on semen volume, sperm concentration or total sperm production (P ≥ 0.553). Total motility of sperm was not impacted by diet (P = 0.115); although, VC tended (P = 0.064) to have a greater progressive motility than CDE. Percentages of morphologically normal sperm and normal acrosomes were not affected by dietary supplementation (P ≥ 0.157). Period effects were observed for most semen quality parameters, with quality generally becoming reduced over time. The present study demonstrates that increased supplementation of vitamins beyond PIC recommendations was not beneficial for boar reproduction during the summer.

Published
2019
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3. Brain function and clinical characterization in the Boston adolescent neuroimaging of depression and anxiety study

Author

N.A. Hubbard, V. Siless, I.R. Frosch, M. Goncalves, N. Lo, J. Wang, C.C.C. Bauer, K. Conroy, E. Cosby, A. Hay, R. Jones, M. Pinaire, F. Vaz De Souza, G. Vergara, S. Ghosh, A. Henin, D.R. Hirshfeld-Becker, S.G. Hofmann, I.M. Rosso, R.P. Auerbach, D.A. Pizzagalli, A. Yendiki, J.D.E. Gabrieli, and S. Whitfield-Gabrieli

Subjects
Computer applications to medicine. Medical informatics, R858-859.7, Neurology. Diseases of the nervous system, RC346-429
Abstract

We present a Human Connectome Project study tailored toward adolescent anxiety and depression. This study is one of the first studies of the Connectomes Related to Human Diseases initiative and is collecting structural, functional, and diffusion-weighted brain imaging data from up to 225 adolescents (ages 14–17 years), 150 of whom are expected to have a current diagnosis of an anxiety and/or depressive disorder. Comprehensive clinical and neuropsychological evaluations and longitudinal clinical data are also being collected. This article provides an overview of task functional magnetic resonance imaging (fMRI) protocols and preliminary findings (N = 140), as well as clinical and neuropsychological characterization of adolescents. Data collection is ongoing for an additional 85 adolescents, most of whom are expected to have a diagnosis of an anxiety and/or depressive disorder. Data from the first 140 adolescents are projected for public release through the National Institutes of Health Data Archive (NDA) with the timing of this manuscript. All other data will be made publicly-available through the NDA at regularly scheduled intervals. This article is intended to serve as an introduction to this project as well as a reference for those seeking to clinical, neurocognitive, and task fMRI data from this public resource.

Published
2020
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4. Variations of the Physical and Chemical Characteristics of Sanitary Landfill Leachate after Percolation into Tropical Soils

Author

M. Goncalves Miguel, L. Belinassi, L.M. Domingues, E.A.A. Nour, and S.Y. Pereira

Subjects
Chemical engineering, TP155-156, Computer engineering. Computer hardware, TK7885-7895
Abstract

Tropical soils are common in Brazil and present very peculiar geotechnical properties, such as fine particle aggregation; natural cementation; and high porosity, which often turn away from the classical models of the Soil Mechanics. Due to this, they are now the focus of recent studies for use as alternative materials for several applications in geotechnical site. This research studies two tropical soils from the Southeastern Brazil to evaluate the variations of the physical and chemical characteristics of sanitary landfill leachate after percolation into these soils. Soil samples were submitted to geotechnical, physical, chemical and mineralogical tests. After these tests, soil samples were compacted with 3 % above their optimum moisture content and placed in polyvinyl chloride columns. The leachate was collected from a regional sanitary landfill and characterized by physical and chemical tests with relation to volatile fatty acid (VFA), chemical oxygen demand (COD), pH, alkalinity, and metals (Cr, Mn, Fe, Co, Ni, Cu, Zn and Pb), before and after percolation into the soils by means of column tests. Curves of concentration versus percolation time for COD, VFA, and metals were obtained for the two soils. COD concentration increased with percolation time for the two soils, while the adsorption/desorption behaviours were different for the two soil, mainly for VFA, Pb, Ni and Co.

Published
2012
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5. Olive Mill Wastewater Anaerobically Digested: Phenolic Compounds with Antiradical Activity

Author

F. La Cara, E. Ionata, G. Del Monaco, L. Marcolongo, M. Goncalves, and I. Paula Marques

Subjects
Chemical engineering, TP155-156, Computer engineering. Computer hardware, TK7885-7895
Abstract

The recovery of phenolic compounds, present in the olive fruits and its by-products, has been intensively studied by the antioxidant properties. Olive mill wastewater (OMW) is a phenolic-rich industrial effluent that can be advantageously valorized by the anaerobic digestion to the methane and agricultural fertilizer productions. The objective of this work was to evaluate the antiradical activity of OMW after anaerobic digestion in order to maximize the valorization of this type of effluents. The digested flow was obtained from an anaerobic hybrid reactor treating OMW at different organic loading rates (OLR), from 3.3 to 7.1 kg COD m3 d-1. OLR rise was applied by increasing progressively the OMW volume fraction from 8 % to 83 % in the feed mixture. The input and output streams, obtained at different OMW volume fractions, were characterized in terms of antiradical activity and phenolic compounds identification and quantification. Despite of the fraction decrease on total phenolic compounds provided by OMW anaerobic digestion, the antiradical activity is still significantly high (EC50 = 3.24) in the digested effluent. Oleuropein was the main phenolic compound present in the substrate before and after anaerobic digestion (about 15 % of the initial value). Others phenolic compounds present are: gallic acid, hydroxytyrosol, tyrosol, and quercetin. These data confirmed that, after the OMW anaerobic treatment to produce biomethane, the remaining flow yet contain useful compounds with antiradical activity.

Published
2012
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7. Mg/Si mineralogical ratio of low-mass planet hosts. Correction for the NLTE effects

Author

Adibekyan, V., da Silva, H. M. Goncalves, Santos, S. G. Sousa N. C., Mena, E. Delgado, and Hakobyan, A. A.

Subjects
Astrophysics - Earth and Planetary Astrophysics, Astrophysics - Solar and Stellar Astrophysics
Abstract

Mg/Si and Fe/Si ratios are important parameters that control the composition of rocky planets. In this work we applied non-LTE correction to the Mg and Si abundances of stars with and without planets to confirm/infirm our previous findings that [Mg/Si] atmospheric abundance is systematically higher for Super-Earth/Neptune-mass planet hosts than stars without planets. Our results show that the small differences of stellar parameters observed in these two groups of stars are not responsible for the already reported difference in the [Mg/Si] ratio. Thus, the high [Mg/Si] ratio of Neptunian hosts is probably related to the formation efficiency of these planets in such environments., Comment: In press. Astrophysics, Vol. 60, No. 3, September , 2017

Published
2017
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13. Trigger and Aperture of the Surface Detector Array of the Pierre Auger Observatory

Author

Abraham, J., Abreu, P., Aglietta, M., Aguirre, C., Ahn, E. J., Allard, D., Allekotte, I., Allen, J., Alvarez-Muñiz, J., Ambrosio, M., Anchordoqui, L., Andringa, S., Anzalone, A., Aramo, C., Arganda, E., Argirò, S., Arisaka, K., Arneodo, F., Arqueros, F., Asch, T., Asorey, H., Assis, P., Aublin, J., Ave, M., Avila, G., Bäcker, T., Badagnani, D., Barber, K. B., Barbosa, A. F., Barroso, S. L. C., Baughman, B., Bauleo, P., Beatty, J. J., Beau, T., Becker, B. R., Becker, K. H., Bellétoile, A., Bellido, J. A., BenZvi, S., Berat, C., Bernardini, P., Bertou, X., Biermann, P. L., Billoir, P., Blanch-Bigas, O., Blanco, F., Bleve, C., Blümer, H., Boháčová, M., Boncioli, D., Bonifazi, C., Bonino, R., Borodai, N., Brack, J., Brogueira, P., Brown, W. C., Bruijn, R., Buchholz, P., Bueno, A., Burton, R. E., Busca, N. G., Caballero-Mora, K. S., Caramete, L., Caruso, R., Carvalho, W., Castellina, A., Catalano, O., Cazon, L., Cester, R., Chauvin, J., Chiavassa, A., Chinellato, J. A., Chou, A., Chudoba, J., Chye, J., Clay, R. W., Colombo, E., Conceição, R., Connolly, B., Contreras, F., Coppens, J., Cordier, A., Cotti, U., Coutu, S., Covault, C. E., Creusot, A., Criss, A., Cronin, J., Curutiu, A., Dagoret-Campagne, S., Dallier, R., Daumiller, K., Dawson, B. R., de Almeida, R. M., De Domenico, M., De Donato, C., de Jong, S. J., De La Vega, G., Junior, W. J. M. de Mello, Neto, J. R. T. de Mello, De Mitri, I., de Souza, V., de Vries, K. D., Decerprit, G., del Peral, L., Deligny, O., Della Selva, A., Fratte, C. Delle, Dembinski, H., Di Giulio, C., Diaz, J. C., Diep, P. N., Dobrigkeit, C., D'Olivo, J. C., Dong, P. N., Dorofeev, A., Anjos, J. C. dos, Dova, M. T., D'Urso, D., Dutan, I., DuVernois, M. A., Engel, R., Erdmann, M., Escobar, C. O., Etchegoyen, A., Luis, P. Facal San, Falcke, H., Farrar, G., Fauth, A. C., Fazzini, N., Ferrer, F., Ferrero, A., Fick, B., Filevich, A., Filipčič, A., Fleck, I., Fliescher, S., Fracchiolla, C. E., Fraenkel, E. D., Fulgione, W., Gamarra, R. F., Gambetta, S., García, B., Gámez, D. García, Garcia-Pinto, D., Garrido, X., Gelmini, G., Gemmeke, H., Ghia, P. L., Giaccari, U., Giller, M., Glass, H., Goggin, L. M., Gold, M. S., Golup, G., Albarracin, F. Gomez, Berisso, M. Gómez, Gonçalves, P., Amaral, M. Gonçalves do, Gonzalez, D., Gonzalez, J. G., Góra, D., Gorgi, A., Gouffon, P., Gozzini, S. R., Grashorn, E., Grebe, S., Grigat, M., Grillo, A. F., Guardincerri, Y., Guarino, F., Guedes, G. P., Gutiérrez, J., Hague, J. D., Halenka, V., Hansen, P., Harari, D., Harmsma, S., Harton, J. L., Haungs, A., Healy, M. D., Hebbeker, T., Hebrero, G., Heck, D., Hojvat, C., Holmes, V. C., Homola, P., Hörandel, J. R., Horneffer, A., Hrabovský, M., Huege, T., Hussain, M., Iarlori, M., Insolia, A., Ionita, F., Italiano, A., Jiraskova, S., Kaducak, M., Kampert, K. H., Karova, T., Kasper, P., Kégl, B., Keilhauer, B., Kemp, E., Kieckhafer, R. M., Klages, H. O., Kleifges, M., Kleinfeller, J., Knapik, R., Knapp, J., Koang, D. -H., Krieger, A., Krömer, O., Kruppke-Hansen, D., Kuehn, F., Kuempel, D., Kulbartz, K., Kunka, N., Kusenko, A., La Rosa, G., Lachaud, C., Lago, B. L., Lautridou, P., Leão, M. S. A. B., Lebrun, D., Lebrun, P., Lee, J., de Oliveira, M. A. Leigui, Lemiere, A., Letessier-Selvon, A., Leuthold, M., Lhenry-Yvon, I., López, R., Agüera, A. Lopez, Louedec, K., Bahilo, J. Lozano, Lucero, A., Lyberis, H., Maccarone, M. C., Macolino, C., Maldera, S., Mandat, D., Mantsch, P., Mariazzi, A. G., Maris, I. C., Falcon, H. R. Marquez, Martello, D., Bravo, O. Martínez, Mathes, H. J., Matthews, J., Matthews, J. A. J., Matthiae, G., Maurizio, D., Mazur, P. O., McEwen, M., McNeil, R. R., Medina-Tanco, G., Melissas, M., Melo, D., Menichetti, E., Menshikov, A., Meyhandan, R., Micheletti, M. I., Miele, G., Miller, W., Miramonti, L., Mollerach, S., Monasor, M., Ragaigne, D. Monnier, Montanet, F., Morales, B., Morello, C., Moreno, J. C., Morris, C., Mostafá, M., Moura, C. A., Mueller, S., Muller, M. A., Mussa, R., Navarra, G., Navarro, J. L., Navas, S., Necesal, P., Nellen, L., Newman-Holmes, C., Newton, D., Nhung, P. T., Nierstenhoefer, N., Nitz, D., Nosek, D., Nožka, L., Nyklicek, M., Oehlschläger, J., Olinto, A., Oliva, P., Olmos-Gilbaja, V. M., Ortiz, M., Pacheco, N., Selmi-Dei, D. Pakk, Palatka, M., Pallotta, J., Parente, G., Parizot, E., Parlati, S., Pastor, S., Patel, M., Paul, T., Pavlidou, V., Payet, K., Pech, M., Pȩkala, J., Pepe, I. M., Perrone, L., Pesce, R., Petermann, E., Petrera, S., Petrinca, P., Petrolini, A., Petrov, Y., Petrovic, J., Pfendner, C., Piegaia, R., Pierog, T., Pimenta, M., Pinto, T., Pirronello, V., Pisanti, O., Platino, M., Pochon, J., Ponce, V. H., Pontz, M., Privitera, P., Prouza, M., Quel, E. J., Rautenberg, J., Ravel, O., Ravignani, D., Redondo, A., Revenu, B., Rezende, F. A. S., Ridky, J., Riggi, S., Risse, M., Rivière, C., Rizi, V., Robledo, C., Rodriguez, G., Martino, J. Rodriguez, Rojo, J. Rodriguez, Rodriguez-Cabo, I., Rodríguez-Frías, M. D., Ros, G., Rosado, J., Rossler, T., Roth, M., Rouillé-d'Orfeuil, B., Roulet, E., Rovero, A. C., Salamida, F., Salazar, H., Salina, G., Sánchez, F., Santander, M., Santo, C. E., Santos, E. M., Sarazin, F., Sarkar, S., Sato, R., Scharf, N., Scherini, V., Schieler, H., Schiffer, P., Schmidt, A., Schmidt, F., Schmidt, T., Scholten, O., Schoorlemmer, H., Schovancova, J., Schovánek, P., Schroeder, F., Schulte, S., Schüssler, F., Schuster, D., Sciutto, S. J., Scuderi, M., Segreto, A., Semikoz, D., Settimo, M., Shellard, R. C., Sidelnik, I., Siffert, B. B., Sigl, G., Śmiałkowski, A., Šmída, R., Smith, B. E., Snow, G. R., Sommers, P., Sorokin, J., Spinka, H., Squartini, R., Strazzeri, E., Stutz, A., Suarez, F., Suomijärvi, T., Supanitsky, A. D., Sutherland, M. S., Swain, J., Szadkowski, Z., Tamashiro, A., Tamburro, A., Tarutina, T., Taşcău, O., Tcaciuc, R., Tcherniakhovski, D., Tegolo, D., Thao, N. T., Thomas, D., Ticona, R., Tiffenberg, J., Timmermans, C., Tkaczyk, W., Peixoto, C. J. Todero, Tomé, B., Tonachini, A., Torres, I., Travnicek, P., Tridapalli, D. B., Tristram, G., Trovato, E., Tueros, M., Ulrich, R., Unger, M., Urban, M., Galicia, J. F. Valdés, Valiño, I., Valore, L., Berg, A. M. van den, Vázquez, J. R., Vázquez, R. A., Veberič, D., Velarde, A., Venters, T., Verzi, V., Videla, M., Villaseñor, L., Vorobiov, S., Voyvodic, L., Wahlberg, H., Wahrlich, P., Wainberg, O., Warner, D., Watson, A. A., Westerhoff, S., Whelan, B. J., Wieczorek, G., Wiencke, L., Wilczyńska, B., Wilczyński, H., Wileman, C., Winnick, M. G., Wu, H., Wundheiler, B., Yamamoto, T., Younk, P., Yuan, G., Yushkov, A., Zas, E., Zavrtanik, D., Zavrtanik, M., Zaw, I., Zepeda, A., and Ziolkowski, M.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics
Abstract

The surface detector array of the Pierre Auger Observatory consists of 1600 water-Cherenkov detectors, for the study of extensive air showers (EAS) generated by ultra-high-energy cosmic rays. We describe the trigger hierarchy, from the identification of candidate showers at the level of a single detector, amongst a large background (mainly random single cosmic ray muons), up to the selection of real events and the rejection of random coincidences. Such trigger makes the surface detector array fully efficient for the detection of EAS with energy above $3\times 10^{18}$ eV, for all zenith angles between 0$^\circ$ and 60$^\circ$, independently of the position of the impact point and of the mass of the primary particle. In these range of energies and angles, the exposure of the surface array can be determined purely on the basis of the geometrical acceptance., Comment: 29 pages, 12 figures

Published
2011
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14. The Fluorescence Detector of the Pierre Auger Observatory

Author

The Pierre Auger Collaboration, Abraham, J., Abreu, P., Aglietta, M., Aguirre, C., Ahn, E. J., Allard, D., Allekotte, I., Allen, J., Allison, P., Alvarez-Muñiz, J., Ambrosio, M., Anchordoqui, L., Andringa, S., Anzalone, A., Aramo, C., Arganda, E., Argirò, S., Arisaka, K., Arneodo, F., Arqueros, F., Asch, T., Asorey, H., Assis, P., Aublin, J., Ave, M., Avila, G., Bacher, A., Bäcker, T., Badagnani, D., Barber, K. B., Barbosa, A. F., Barbosa, H. J. M., Barenthien, N., Barroso, S. L. C., Baughman, B., Bauleo, P., Beatty, J. J., Beau, T., Becker, B. R., Becker, K. H., Bellétoile, A., Bellido, J. A., BenZvi, S., Berat, C., Bernardini, P., Bertou, X., Biermann, P. L., Billoir, P., Blanch-Bigas, O., Blanco, F., Bleve, C., Blümer, H., Boháčová, M., Bollmann, E., Bolz, H., Bonifazi, C., Bonino, R., Borodai, N., Bracci, F., Brack, J., Brogueira, P., Brown, W. C., Bruijn, R., Buchholz, P., Bueno, A., Burton, R. E., Busca, N. G., Caballero-Mora, K. S., Caramete, D. CaminL., Caruso, R., Carvalho, W., Castellina, A., Castro, J., Catalano, O., Cazon, L., Cester, R., Chauvin, J., Chiavassa, A., Chinellato, J. A., Chou, A., Chudoba, J., Chye, J., Clark, P. D. J., Clay, R. W., Colombo, E., Conceição, R., Connolly, B., Contreras, F., Coppens, J., Cordero, A., Cordier, A., Cotti, U., Coutu, S., Covault, C. E., Creusot, A., Criss, A., Cronin, J. W., Cuautle, J., Curutiu, A., Dagoret-Campagne, S., Dallier, R., Daudo, F., Daumiller, K., Dawson, B. R., de Almeida, R. M., De Domenico, M., De Donato, C., de Jong, S. J., De La Vega, G., Junior, W. J. M. de Mello, Neto, J. R. T. de Mello, De Mitri, I., de Souza, V., de Vries, K. D., Decerprit, G., del Peral, L., Deligny, O., Della Selva, A., Fratte, C. Delle, Dembinski, H., Di Giulio, C., Diaz, J. C., Diep, P. N., Dobrigkeit, C., D'Olivo, J. C., Dong, P. N., Dornic, D., Dorofeev, A., Anjos, J. C. dos, Dova, M. T., D'Urso, D., Dutan, I., DuVernois, M. A., Engel, R., Erdmann, M., Escobar, C. O., Etchegoyen, A., Luis, P. Facal San, Falcke, H., Farrar, G., Fauth, A. C., Fazzini, N., Ferrer, F., Ferrero, A., Fick, B., Filevich, A., Filipčič, A., Fleck, I., Fliescher, S., Fonte, R., Fracchiolla, C. E., Fraenkel, E. D., Fulgione, W., Gamarra, R. F., Gambetta, S., García, B., Gámez, D. García, Garcia-Pinto, D., Garrido, X., Geenen, H., Gelmini, G., Gemmeke, H., Ghia, P. L., Giaccari, U., Gibbs, K., Giller, M., Gitto, J., Glass, H., Goggin, L. M., Gold, M. S., Golup, G., Albarracin, F. Gomez, Berisso, M. Gómez, Vitale, P. F. Gomez, Gonçalves, P., Amaral, M. Gonçalves do, Gonzalez, D., Gonzalez, J. G., Góra, D., Gorgi, A., Gouffon, P., Grashorn, E., Grassi, V., Grebe, S., Grigat, M., Grillo, A. F., Grygar, J., Guardincerri, Y., Guardone, N., Guerard, C., Guarino, F., Gumbsheimer, R., Guedes, G. P., Gutiérrez, J., Hague, J. D., Halenka, V., Hansen, P., Harari, D., Harmsma, S., Hartmann, S., Harton, J. L., Haungs, A., Healy, M. D., Hebbeker, T., Hebrero, G., Heck, D., Hojvat, C., Holmes, V. C., Homola, P., Hofman, G., Hörandel, J. R., Horneffer, A., Horvat, M., Hrabovský, M., Hucker, H., Huege, T., Hussain, M., Iarlori, M., Insolia, A., Ionita, F., Italiano, A., Jiraskova, S., Kaducak, M., Kampert, K. H., Karova, T., Kasper, P., Kégl, B., Keilhauer, B., Kemp, E., Kern, H., Kieckhafer, R. M., Klages, H. O., Kleifges, M., Kleinfeller, J., Knapik, R., Knapp, J., Koang, D. -H., Kopmann, A., Krieger, A., Krömer, O., Kruppke-Hansen, D., Kuempel, D., Kunka, N., Kusenko, A., La Rosa, G., Lachaud, C., Lago, B. L., Lautridou, P., Leão, M. S. A. B., Lebrun, D., Lebrun, P., Lee, J., de Oliveira, M. A. Leigui, Lemiere, A., Letessier-Selvon, A., Leuthold, M., Lhenry-Yvon, I., López, R., Agüera, A. Lopez, Louedec, K., Bahilo, J. Lozano, Lucero, A., Lyberis, H., Maccarone, M. C., Macolino, C., Maldera, S., Malek, M., Mandat, D., Mantsch, P., Marchetto, F., Mariazzi, A. G., Maris, I. C., Falcon, H. R. Marquez, Martello, D., Martineau, O., Bravo, O. Martínez, Mathes, H. J., Matthews, J., Matthews, J. A. J., Matthiae, G., Maurizio, D., Mazur, P. O., McEwen, M., McNeil, R. R., Medina-Tanco, G., Melissas, M., Melo, D., Menichetti, E., Menshikov, A., Meyhandan, R., Micheletti, M. I., Miele, G., Miller, W., Miramonti, L., Mollerach, S., Monasor, M., Ragaigne, D. Monnier, Montanet, F., Morales, B., Morello, C., Moreno, J. C., Morris, C., Mostafá, M., Moura, C. A., Mucchi, M., Mueller, S., Muller, M. A., Mussa, R., Navarra, G., Navarro, J. L., Navas, S., Necesal, P., Nellen, L., Nerling, F., Newman-Holmes, C., Newton, D., Nhung, P. T., Nicotra, D., Nierstenhoefer, N., Nitz, D., Nosek, D., Nožka, L., Nyklicek, M., Oehlschläger, J., Olinto, A., Oliva, P., Olmos-Gilbaja, V. M., Ortiz, M., Ortolani, F., Oßwald, B., Pacheco, N., Selmi-Dei, D. Pakk, Palatka, M., Pallotta, J., Parente, G., Parizot, E., Parlati, S., Pastor, S., Patel, M., Paul, T., Pavlidou, V., Payet, K., Pech, M., Pȩkala, J., Pepe, I. M., Perrone, L., Pesce, R., Petermann, E., Petrera, S., Petrinca, P., Petrolini, A., Petrov, Y., Petrovic, J., Pfendner, C., Pichel, A., Piegaia, R., Pierog, T., Pimenta, M., Pinto, T., Pirronello, V., Pisanti, O., Platino, M., Pochon, J., Ponce, V. H., Pontz, M., Pouryamout, J., Prado Jr., L., Privitera, P., Prouza, M., Quel, E. J., Rautenberg, G. Raia J., Ravel, O., Ravignani, D., Redondo, A., Reis, H. C., Reucroft, S., Revenu, B., Rezende, F. A. S., Ridky, J., Riggi, S., Risse, M., Rivière, C., Rizi, V., Robledo, C., Roberts, M. D., Rodriguez, G., Martino, J. Rodriguez, Rojo, J. Rodriguez, Rodriguez-Cabo, I., Rodríguez-Frías, M. D., Ros, G., Rosado, J., Rossler, T., Roth, M., Rouillé-d'Orfeuil, B., Roulet, E., Rovero, A. C., Salamida, F., b, H. Salazar, Salina, G., Sánchez, F., Santander, M., Santo, C. E., Santos, E. M., Sarazin, F., Sarkar, S., Sato, R., Scharf, N., Scherini, V., Schieler, H., Schiffer, P., Schmidt, G. Schleif A., Schmidt, F., Schmidt, T., Scholten, O., Schoorlemmer, H., Schovancova, J., Schovánek, P., Schroeder, F., Schulte, S., Schüssler, F., Schuster, D., Sciutto, S. J., Scuderi, M., Segreto, A., Semikoz, D., Sequieros, G., Settimo, M., Shellard, R. C., Sidelnik, I., Siffert, B. B., Smiałkowski, A., Šmída, R., Smith, A. G. K., Smith, B. E., Snow, G. R., Sommers, P., Sorokin, J., Spinka, H., Squartini, R., Strazzeri, E., Stutz, A., Suarez, F., Suomijärvi, T., Supanitsky, A. D., Sutherland, M. S., Swain, J., Szadkowski, Z., Tamashiro, A., Tamburro, A., Tarutina, T., Taşcău, O., Tcaciuc, R., Tcherniakhovski, D., Thao, N. T., Thomas, D., Ticona, R., Tiffenberg, J., Timmermans, C., Tkaczyk, W., Peixoto, C. J. Todero, Tomé, B., Tonachini, A., Torres, I., Trapani, P., Travnicek, P., Tridapalli, D. B., Tristram, G., Trovato, E., Tuci, V., Tueros, M., Tusi, E., Ulrich, R., Unger, M., Urban, M., Galicia, J. F. Valdés, Valiño, I., Valore, L., Berg, A. M. van den, Vázquez, J. R., Vázquez, R. A., Veberič, D., Velarde, A., Venters, T., Verzi, V., Videla, M., Villaseñor, L., Vitali, G., Vorobiov, S., Voyvodic, L., Wahlberg, H., Wahrlich, P., Wainberg, O., Warner, D., Westerhoff, S., Whelan, B. J., Wild, N., Wiebusch, C., Wieczorek, G., Wiencke, L., Wilczyńska, B., Wilczyński, H., Wileman, C., Winnick, M. G., Wörner, G., Wu, H., Wundheiler, B., Yamamoto, T., Younk, P., Yuan, G., Yushkov, A., Zas, E., Zavrtanik, D., Zavrtanik, M., Zaw, I., b, A. Zepeda, and Ziolkowski, M.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics
Abstract

The Pierre Auger Observatory is a hybrid detector for ultra-high energy cosmic rays. It combines a surface array to measure secondary particles at ground level together with a fluorescence detector to measure the development of air showers in the atmosphere above the array. The fluorescence detector comprises 24 large telescopes specialized for measuring the nitrogen fluorescence caused by charged particles of cosmic ray air showers. In this paper we describe the components of the fluorescence detector including its optical system, the design of the camera, the electronics, and the systems for relative and absolute calibration. We also discuss the operation and the monitoring of the detector. Finally, we evaluate the detector performance and precision of shower reconstructions., Comment: 53 pages. Submitted to Nuclear Instruments and Methods in Physics Research Section A

Published
2009
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15. Calibration and Monitoring of the Pierre Auger Observatory

Author

The Pierre Auger Collaboration, Abraham, J., Abreu, P., Aglietta, M., Aguirre, C., Ahn, E. J., Allard, D., Allekotte, I., Allen, J., Alvarez-Muñiz, J., Ambrosio, M., Anchordoqui, L., Andringa, S., Anzalone, A., Aramo, C., Arganda, E., Argirò, S., Arisaka, K., Arneodo, F., Arqueros, F., Asch, T., Asorey, H., Assis, P., Aublin, J., Ave, M., Avila, G., Bäcker, T., Badagnani, D., Barber, K. B., Barbosa, A. F., Barroso, S. L. C., Baughman, B., Bauleo, P., Beatty, J. J., Beau, T., Becker, B. R., Becker, K. H., Bellétoile, A., Bellido, J. A., BenZvi, S., Berat, C., Bernardini, P., Bertou, X., Biermann, P. L., Billoir, P., Blanch-Bigas, O., Blanco, F., Bleve, C., Blümer, H., Boháčová, M., Boncioli, D., Bonifazi, C., Bonino, R., Borodai, N., Brack, J., Brogueira, P., Brown, W. C., Bruijn, R., Buchholz, P., Bueno, A., Burton, R. E., Busca, N. G., Caballero-Mora, K. S., Caramete, L., Caruso, R., Carvalho, W., Castellina, A., Catalano, O., Cazon, L., Cester, R., Chauvin, J., Chiavassa, A., Chinellato, J. A., Chou, A., Chudoba, J., Chye, J., Clay, R. W., Colombo, E., Conceição, R., Connolly, B., Contreras, F., Coppens, J., Cordier, A., Cotti, U., Coutu, S., Covault, C. E., Creusot, A., Criss, A., Cronin, J., Curutiu, A., Dagoret-Campagne, S., Dallier, R., Daumiller, K., Dawson, B. R., de Almeida, R. M., De Domenico, M., De Donato, C., de Jong, S. J., De La Vega, G., Junior, W. J. M. de Mello, Neto, J. R. T. de Mello, De Mitri, I., de Souza, V., de Vries, K. D., Decerprit, G., del Peral, L., Deligny, O., Della Selva, A., Fratte, C. Delle, Dembinski, H., DiGiulio, C., Diaz, J. C., Diep, P. N., Dobrigkeit, C., D'Olivo, J. C., Dong, P. N., Dorofeev, A., Anjos, J. C. dos, Dova, M. T., D'Urso, D., Dutan, I., DuVernois, M. A., Engel, R., Erdmann, M., Escobar, C. O., Etchegoyen, A., Luis, P. Facal San, Falcke, H., Farrar, G., Fauth, A. C., Fazzini, N., Ferrer, F., Ferrero, A., Fick, B., Filevich, A., Filipčič, A., Fleck, I., Fliescher, S., Fracchiolla, C. E., Fraenkel, E. D., Fulgione, W., Gamarra, R. F., Gambetta, S., García, B., GarcíaGámez, D., Garcia-Pinto, D., Garrido, X., Gelmini, G., Gemmeke, H., Ghia, P. L., Giaccari, U., Giller, M., Glass, H., Goggin, L. M., Gold, M. S., Golup, G., Albarracin, F. Gomez, Berisso, M. Gómez, Gonçalves, P., Amaral, M. Gonçalves do, Gonzalez, D., Gonzalez, J. G., Góra, D., Gorgi, A., Gouffon, P., Gozzini, S. R., Grashorn, E., Grebe, S., Grigat, M., Grillo, A. F., Guardincerri, Y., Guarino, F., Guedes, G. P., Gutiérrez, J., Hague, J. D., Halenka, V., Hansen, P., Harari, D., Harmsma, S., Harton, J. L., Haungs, A., Healy, M. D., Hebbeker, T., Hebrero, G., Heck, D., Hojvat, C., Holmes, V. C., Homola, P., Hörandel, J. R., Horneffer, A., Hrabovský, M., Huege, T., Hussain, M., Iarlori, M., Insolia, A., Ionita, F., Italiano, A., Jiraskova, S., Kaducak, M., Kampert, K. H., Karova, T., Kasper, P., Kégl, B., Keilhauer, B., Kemp, E., Kieckhafer, R. M., Klages, H. O., Kleifges, M., Kleinfeller, J., Knapik, R., Knapp, J., Koang, D. -H., Krieger, A., Krömer, O., Kruppke-Hansen, D., Kuehn, F., Kuempel, D., Kulbartz, K., Kunka, N., Kusenko, A., LaRosa, G., Lachaud, C., Lago, B. L., Lautridou, P., Leão, M. S. A. B., Lebrun, D., Lebrun, P., Lee, J., de Oliveira, M. A. Leigui, Lemiere, A., Letessier-Selvon, A., Leuthold, M., Lhenry-Yvon, I., López, R., Agüera, A. Lopez, Louedec, K., Bahilo, J. Lozano, Lucero, A., Lyberis, H., Maccarone, M. C., Macolino, C., Maldera, S., Mandat, D., Mantsch, P., Mariazzi, A. G., Maris, I. C., Falcon, H. R. Marquez, Martello, D., Bravo, O. Martínez, Mathes, H. J., Matthews, J., Matthews, J. A. J., Matthiae, G., Maurizio, D., Mazur, P. O., McEwen, M., McNeil, R. R., Medina-Tanco, G., Melissas, M., Melo, D., Menichetti, E., Menshikov, A., Meyhandan, R., Micheletti, M. I., Miele, G., Miller, W., Miramonti, L., Mollerach, S., Monasor, M., Ragaigne, D. Monnier, Montanet, F., Morales, B., Morello, C., Moreno, J. C., Morris, C., Mostafá, M., Moura, C. A., Mueller, S., Muller, M. A., Mussa, R., Navarra, G., Navarro, J. L., Navas, S., Necesal, P., Nellen, L., Newman-Holmes, C., Newton, D., Nhung, P. T., Nierstenhoefer, N., Nitz, D., Nosek, D., Nožka, L., Nyklicek, M., Oehlschläger, J., Olinto, A., Oliva, P., Olmos-Gilbaja, V. M., Ortiz, M., Pacheco, N., Selmi-Dei, D. Pakk, Palatka, M., Pallotta, J., Parente, G., Parizot, E., Parlati, S., Pastor, S., Patel, M., Paul, T., Pavlidou, V., Payet, K., Pech, M., Pȩkala, J., Pepe, I. M., Perrone, L., Pesce, R., Petermann, E., Petrera, S., Petrinca, P., Petrolini, A., Petrov, Y., Petrovic, J., Pfendner, C., Piegaia, R., Pierog, T., Pimenta, M., Pinto, T., Pirronello, V., Pisanti, O., Platino, M., Pochon, J., Ponce, V. H., Pontz, M., Privitera, P., Prouza, M., Quel, E. J., Rautenberg, J., Ravel, O., Ravignani, D., Redondo, A., Revenu, B., Rezende, F. A. S., Ridky, J., Riggi, S., Risse, M., Rivière, C., Rizi, V., Robledo, C., Rodriguez, G., Martino, J. Rodriguez, Rojo, J. Rodriguez, Rodriguez-Cabo, I., Rodríguez-Frías, M. D., Ros, G., Rosado, J., Rossler, T., Roth, M., Rouillé-d'Orfeuil, B., Roulet, E., Rovero, A. C., Salamida, F., Salazar, H., Salina, G., Sánchez, F., Santander, M., Santo, C. E., Santos, E. M., Sarazin, F., Sarkar, S., Sato, R., Scharf, N., Scherini, V., Schieler, H., Schiffer, P., Schmidt, A., Schmidt, F., Schmidt, T., Scholten, O., Schoorlemmer, H., Schovancova, J., Schovánek, P., Schroeder, F., Schulte, S., Schüssler, F., Schuster, D., Sciutto, S. J., Scuderi, M., Segreto, A., Semikoz, D., Settimo, M., Shellard, R. C., Sidelnik, I., Siffert, B. B., Sigl, G., Śmiałkowski, A., Šmída, R., Smith, B. E., Snow, G. R., Sommers, P., Sorokin, J., Spinka, H., Squartini, R., Strazzeri, E., Stutz, A., Suarez, F., Suomijärvi, T., Supanitsky, A. D., Sutherland, M. S., Swain, J., Szadkowski, Z., Tamashiro, A., Tamburro, A., Tarutina, T., Taşcău, O., Tcaciuc, R., Tcherniakhovski, D., Tegolo, D., Thao, N. T., Thomas, D., Ticona, R., Tiffenberg, J., Timmermans, C., Tkaczyk, W., Peixoto, C. J. Todero, Tomé, B., Tonachini, A., Torres, I., Travnicek, P., Tridapalli, D. B., Tristram, G., Trovato, E., Tueros, M., Ulrich, R., Unger, M., Urban, M., Galicia, J. F. Valdés, Valiño, I., Valore, L., vandenBerg, A. M., Vázquez, J. R., Vázquez, R. A., Veberič, D., Velarde, A., Venters, T., Verzi, V., Videla, M., Villaseñor, L., Vorobiov, S., Voyvodic, L., Wahlberg, H., Wahrlich, P., Wainberg, O., Warner, D., Watson, A. A., Westerhoff, S., Whelan, B. J., Wieczorek, G., Wiencke, L., Wilczyńska, B., Wilczyński, H., Wileman, C., Winnick, M. G., Wu, H., Wundheiler, B., Yamamoto, T., Younk, P., Yuan, G., Yushkov, A., Zas, E., Zavrtanik, D., Zavrtanik, M., Zaw, I., Zepeda, A., and Ziolkowski, M.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - High Energy Astrophysical Phenomena
Abstract

Reports on the atmospheric monitoring, calibration, and other operating systems of the Pierre Auger Observatory. Contributions to the 31st International Cosmic Ray Conference, Lodz, Poland, July 2009., Comment: Contributions to the 31st International Cosmic Ray Conference, Lodz, Poland, July 2009

Published
2009

16. Operations of and Future Plans for the Pierre Auger Observatory

Author

The Pierre Auger Collaboration, Abraham, J., Abreu, P., Aglietta, M., Aguirre, C., Ahn, E. J., Allard, D., Allekotte, I., Allen, J., Alvarez-Muñiz, J., Ambrosio, M., Anchordoqui, L., Andringa, S., Anzalone, A., Aramo, C., Arganda, E., Argirò, S., Arisaka, K., Arneodo, F., Arqueros, F., Asch, T., Asorey, H., Assis, P., Aublin, J., Ave, M., Avila, G., Bäcker, T., Badagnani, D., Barber, K. B., Barbosa, A. F., Barroso, S. L. C., Baughman, B., Bauleo, P., Beatty, J. J., Beau, T., Becker, B. R., Becker, K. H., Bellétoile, A., Bellido, J. A., BenZvi, S., Berat, C., Bernardini, P., Bertou, X., Biermann, P. L., Billoir, P., Blanch-Bigas, O., Blanco, F., Bleve, C., Blümer, H., Boháčová, M., Boncioli, D., Bonifazi, C., Bonino, R., Borodai, N., Brack, J., Brogueira, P., Brown, W. C., Bruijn, R., Buchholz, P., Bueno, A., Burton, R. E., Busca, N. G., Caballero-Mora, K. S., Caramete, L., Caruso, R., Carvalho, W., Castellina, A., Catalano, O., Cazon, L., Cester, R., Chauvin, J., Chiavassa, A., Chinellato, J. A., Chou, A., Chudoba, J., Chye, J., Clay, R. W., Colombo, E., Conceição, R., Connolly, B., Contreras, F., Coppens, J., Cordier, A., Cotti, U., Coutu, S., Covault, C. E., Creusot, A., Criss, A., Cronin, J., Curutiu, A., agoret-Campagne, S., Dallier, R., Daumiller, K., Dawson, B. R., de Almeida, R. M., De Domenico, M., De Donato, C., de Jong, S. J., De La Vega, G., Junior, W. J. M. de Mello, Neto, J. R. T. de Mello, De Mitri, I., de Souza, V., de Vries, K. D., Decerprit, G., del Peral, L., Deligny, O., Della Selva, A., Fratte, C. Delle, Dembinski, H., DiGiulio, C., Diaz, J. C., Diep, P. N., Dobrigkeit, C., D'Olivo, J. C., Dong, P. N., Dorofeev, A., Anjos, J. C. dos, Dova, M. T., D'Urso, D., Dutan, I., DuVernois, M. A., Engel, R., Erdmann, M., Escobar, C. O., Etchegoyen, A., Luis, P. Facal San, Falcke, H., Farrar, G., Fauth, A. C., Fazzini, N., Ferrer, F., Ferrero, A., Fick, B., Filevich, A., Filipčič, A., Fleck, I., Fliescher, S., Fracchiolla, C. E., Fraenkel, E. D., Fulgione, W., Gamarra, R. F., Gambetta, S., García, B., GarcíaGámez, D., Garcia-Pinto, D., Garrido, X., Gelmini, G., Gemmeke, H., Ghia, P. L., Giaccari, U., Giller, M., Glass, H., Goggin, L. M., Gold, M. S., Golup, G., Albarracin, F. Gomez, Berisso, M. Gómez, Gonçalves, P., Amaral, M. Gonçalves do, Gonzalez, D., Gonzalez, J. G., Góra, D., Gorgi, A., Gouffon, P., Gozzini, S. R., Grashorn, E., Grebe, S., Grigat, M., Grillo, A. F., Guardincerri, Y., Guarino, F., Guedes, G. P., Gutiérrez, J., Hague, J. D., Halenka, V., Hansen, P., Harari, D., Harmsma, S., Harton, J. L., Haungs, A., Healy, M. D., Hebbeker, T., Hebrero, G., Heck, D., Holmes, V. C., Homola, P., Hörandel, J. R., Horneffer, A., Hrabovský, M., Huege, T., Hussain, M., Iarlori, M., Insolia, A., Ionita, F., Italiano, A., Jiraskova, S., Kaducak, M., Kampert, K. H., Karova, T., Kasper, P., Kégl, B., Keilhauer, B., Kemp, E., Kieckhafer, R. M., Klages, H. O., Kleifges, M., Kleinfeller, J., Knapik, R., Knapp, J., Koang, D. -H., Krieger, A., Krömer, O., Kruppke-Hansen, D., Kuehn, F., Kuempel, D., Kulbartz, K., Kunka, N., Kusenko, A., LaRosa, G., Lachaud, C., Lago, B. L., Lautridou, P., Leão, M. S. A. B., Lebrun, D., Lebrun, P., Lee, J., de Oliveira, M. A. Leigui, Lemiere, A., Letessier-Selvon, A., Leuthold, M., Lhenry-Yvon, I., López, R., Agüera, A. Lopez, Louedec, K., Bahilo, J. Lozano, Lucero, A., Lyberis, H., Maccarone, M. C., Macolino, C., Maldera, S., Mandat, D., Mantsch, P., Mariazzi, A. G., Maris, I. C., Falcon, H. R. Marquez, Martello, D., Bravo, O. Martínez, Mathes, H. J., Matthews, J., Matthews, J. A. J., Matthiae, G., Maurizio, D., Mazur, P. O., McEwen, M., McNeil, R. R., Medina-Tanco, G., Melissas, M., Melo, D., Menichetti, E., Menshikov, A., Meyhandan, R., Micheletti, M. I., Miele, G., Miller, W., Miramonti, L., Mollerach, S., Monasor, M., Ragaigne, D. Monnier, Montanet, F., Morales, B., Morello, C., Moreno, J. C., Morris, C., Mostafá, M., Moura, C. A., Mueller, S., Muller, M. A., Mussa, R., Navarra, G., Navarro, J. L., Navas, S., Necesal, P., Nellen, L., Newman-Holmes, C., Newton, D., Nhung, P. T., Nierstenhoefer, N., Nitz, D., Nosek, D., Nožka, L., Nyklicek, M., Oehlschläger, J., Olinto, A., Oliva, P., Olmos-Gilbaja, V. M., Ortiz, M., Pacheco, N., Selmi-Dei, D. Pakk, Palatka, M., Pallotta, J., Parente, G., Parizot, E., Parlati, S., Pastor, S., Patel, M., Paul, T., Pavlidou, V., Payet, K., Pech, M., Pȩkala, J., Pepe, I. M., Perrone, L., Pesce, R., Petermann, E., Petrera, S., Petrinca, P., Petrolini, A., Petrov, Y., Petrovic, J., Pfendner, C., Piegaia, R., Pierog, T., Pimenta, M., Pinto, T., Pirronello, V., Pisanti, O., Platino, M., Pochon, J., Ponce, V. H., Pontz, M., Privitera, P., Prouza, M., Quel, E. J., Rautenberg, J., Ravel, O., Ravignani, D., Redondo, A., Revenu, B., Rezende, F. A. S., Ridky, J., Riggi, S., Risse, M., Rivière, C., Rizi, V., Robledo, C., Rodriguez, G., Martino, J. Rodriguez, Rojo, J. Rodriguez, Rodriguez-Cabo, I., Rodríguez-Frías, M. D., Ros, G., Rosado, J., Rossler, T., Roth, M., Rouillé-d'Orfeuil, B., Roulet, E., Rovero, A. C., Salamida, F., Salazar, H., Salina, G., Sánchez, F., Santander, M., Santo, C. E., Santos, E. M., Sarazin, F., Sarkar, S., Sato, R., Scharf, N., Scherini, V., Schieler, H., Schiffer, P., Schmidt, A., Schmidt, F., Schmidt, T., Scholten, O., Schoorlemmer, H., Schovancova, J., Schovánek, P., Schroeder, F., Schulte, S., Schüssler, F., Schuster, D., Sciutto, S. J., Scuderi, M., Segreto, A., Semikoz, D., Settimo, M., Shellard, R. C., Sidelnik, I., Siffert, B. B., Sigl, G., Śmiałkowski, A., Šmída, R., Smith, B. E., Snow, G. R., Sommers, P., Sorokin, J., Spinka, H., Squartini, R., Strazzeri, E., Stutz, A., Suarez, F., Suomijärvi, T., Supanitsky, A. D., Sutherland, M. S., Swain, J., Szadkowski, Z., Tamashiro, A., Tamburro, A., Tarutina, T., Taşcău, O., Tcaciuc, R., Tcherniakhovski, D., Tegolo, D., Thao, N. T., Thomas, D., Ticona, R., Tiffenberg, J., Timmermans, C., Tkaczyk, W., Peixoto, C. J. Todero, Tomé, B., Tonachini, A., Torres, I., Travnicek, P., Tridapalli, D. B., Tristram, G., Trovato, E., Tueros, M., Ulrich, R., Unger, M., Urban, M., Galicia, J. F. Valdés, Valiño, I., Valore, L., VandenBerg, A. M., Vázquez, J. R., Vázquez, R. A., Veberič, D., Velarde, A., Venters, T., Verzi, V., Videla, M., Villaseñor, L., Vorobiov, S., Voyvodic, L., Wahlberg, H., Wahrlich, P., Wainberg, O., Warner, D., Watson, A. A., Westerhoff, S., Whelan, B. J., Wieczorek, G., Wiencke, L., Wilczyńska, B., Wilczyński, H., Wileman, C., Winnick, M. G., Wu, H., Wundheiler, B., Yamamoto, T., Younk, P., Yuan, G., Yushkov, A., Zas, E., Zavrtanik, D., Zavrtanik, M., Zaw, I., Zepeda, A., and Ziolkowski, M.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - High Energy Astrophysical Phenomena
Abstract

Technical reports on operations and features of the Pierre Auger Observatory, including ongoing and planned enhancements and the status of the future northern hemisphere portion of the Observatory. Contributions to the 31st International Cosmic Ray Conference, Lodz, Poland, July 2009., Comment: Contributions to the 31st ICRC, Lodz, Poland, July 2009

Published
2009

17. Astrophysical Sources of Cosmic Rays and Related Measurements with the Pierre Auger Observatory

Author

The Pierre Auger Collaboration, Abraham, J., Abreu, P., Aglietta, M., Aguirre, C., Ahn, E. J., Allard, D., Allekotte, I., Allen, J., Alvarez-Muñiz, J., Ambrosio, M., Anchordoqui, L., Andringa, S., Anzalone, A., Aramo, C., Arganda, E., Argirò, S., Arisaka, K., Arneodo, F., Arqueros, F., Asch, T., Asorey, H., Assis, P., Aublin, J., Ave, M., Avila, G., Bäcker, T., Badagnani, D., Barber, K. B., Barbosa, A. F., Barroso, S. L. C., Baughman, B., Bauleo, P., Beatty, J. J., Beau, T., Becker, B. R., Becker, K. H., Bellétoile, A., Bellido, J. A., BenZvi, S., Berat, C., Bernardini, P., Bertou, X., Biermann, P. L., Billoir, P., Blanch-Bigas, O., Blanco, F., Bleve, C., Blümer, H., Boháčová, M., Boncioli, D., Bonifazi, C., Bonino, R., Borodai, N., Brack, J., Brogueira, P., Brown, W. C., Bruijn, R., Buchholz, P., Bueno, A., Burton, R. E., Busca, N. G., Caballero-Mora, K. S., Caramete, L., Caruso, R., Carvalho, W., Castellina, A., Catalano, O., Cazon, L., Cester, R., Chauvin, J., Chiavassa, A., Chinellato, J. A., Chou, A., Chudoba, J., Chye, J., Clay, R. W., Colombo, E., Conceição, R., Connolly, B., Contreras, F., Coppens, J., Cordier, A., Cotti, U., Coutu, S., Covault, C. E., Creusot, A., Criss, A., Cronin, J., Curutiu, A., Dagoret-Campagne, S., Dallier, R., Daumiller, K., Dawson, B. R., de Almeida, R. M., De Domenico, M., De Donato, C., de Jong, S. J., De La Vega, G., Junior, W. J. M. de Mello, Neto, J. R. T. de Mello, De Mitri, I., de Souza, V., de Vries, K. D., Decerprit, G., del Peral, L., Deligny, O., Della Selva, A., Fratte, C. Delle, Dembinski, H., DiGiulio, C., Diaz, J. C., Diep, P. N., Dobrigkeit, C., D'Olivo, J. C., Dong, P. N., Dorofeev, A., Anjos, J. C. dos, Dova, M. T., D'Urso, D., Dutan, I., DuVernois, M. A., Engel, R., Erdmann, M., Escobar, C. O., Etchegoyen, A., Luis, P. Facal San, Falcke, H., Farrar, G., Fauth, A. C., Fazzini, N., Ferrer, F., Ferrero, A., Fick, B., Filevich, A., Filipčič, A., Fleck, I., Fliescher, S., Fracchiolla, C. E., Fraenkel, E. D., Fulgione, W., Gamarra, R. F., Gambetta, S., García, B., GarcíaGámez, D., Garcia-Pinto, D., Garrido, X., Gelmini, G., Gemmeke, H., Ghia, P. L., Giaccari, U., Giller, M., Glass, H., Goggin, L. M., Gold, M. S., Golup, G., Albarracin, F. Gomez, Berisso, M. Gómez, Gonçalves, P., Amaral, M. Gonçalves do, Gonzalez, D., Gonzalez, J. G., Góra, D., Gorgi, A., Gouffon, P., Gozzini, S. R., Grashorn, E., Grebe, S., Grigat, M., Grillo, A. F., Guardincerri, Y., Guarino, F., Guedes, G. P., Gutiérrez, J., Hague, J. D., Halenka, V., Hansen, P., Harari, D., Harmsma, S., Harton, J. L., Haungs, A., Healy, M. D., Hebbeker, T., Hebrero, G., Heck, D., Holmes, V. C., Homola, P., Hörandel, J. R., Horneffer, A., Hrabovský, M., Huege, T., Hussain, M., Iarlori, M., Insolia, A., Ionita, F., Italiano, A., Jiraskova, S., Kaducak, M., Kampert, K. H., Karova, T., Kasper, P., Kégl, B., Keilhauer, B., Kemp, E., Kieckhafer, R. M., Klages, H. O., Kleifges, M., Kleinfeller, J., Knapik, R., Knapp, J., Koang, D. -H., Krieger, A., Krömer, O., Kruppke-Hansen, D., Kuehn, F., Kuempel, D., Kulbartz, K., Kunka, N., Kusenko, A., LaRosa, G., Lachaud, C., Lago, B. L., Lautridou, P., Leão, M. S. A. B., Lebrun, D., Lebrun, P., Lee, J., de Oliveira, M. A. Leigui, Lemiere, A., Letessier-Selvon, A., Leuthold, M., Lhenry-Yvon, I., López, R., Agüera, A. Lopez, Louedec, K., Bahilo, J. Lozano, Lucero, A., Lyberis, H., Maccarone, M. C., Macolino, C., Maldera, S., Mandat, D., Mantsch, P., Mariazzi, A. G., Maris, I. C., Falcon, H. R. Marquez, Martello, D., Bravo, O. Martínez, Mathes, H. J., Matthews, J., Matthews, J. A. J., Matthiae, G., Maurizio, D., Mazur, P. O., McEwen, M., McNeil, R. R., Medina-Tanco, G., Melissas, M., Melo, D., Menichetti, E., Menshikov, A., Meyhandan, R., Micheletti, M. I., Miele, G., Miller, W., Miramonti, L., Mollerach, S., Monasor, M., Ragaigne, D. Monnier, Montanet, F., Morales, B., Morello, C., Moreno, J. C., Morris, C., Mostafá, M., Moura, C. A., Mueller, S., Muller, M. A., Mussa, R., Navarra, G., Navarro, J. L., Navas, S., Necesal, P., Nellen, L., Newman-Holmes, C., Newton, D., Nhung, P. T., Nierstenhoefer, N., Nitz, D., Nosek, D., Nožka, L., Nyklicek, M., Oehlschläger, J., Olinto, A., Oliva, P., Olmos-Gilbaja, V. M., Ortiz, M., Pacheco, N., Selmi-Dei, D. Pakk, Palatka, M., Pallotta, J., Parente, G., Parizot, E., Parlati, S., Pastor, S., Patel, M., Paul, T., Pavlidou, V., Payet, K., Pech, M., Pȩkala, J., Pepe, I. M., Perrone, L., Pesce, R., Petermann, E., Petrera, S., Petrinca, P., Petrolini, A., Petrov, Y., Petrovic, J., Pfendner, C., Piegaia, R., Pierog, T., Pimenta, M., Pinto, T., Pirronello, V., Pisanti, O., Platino, M., Pochon, J., Ponce, V. H., Pontz, M., Privitera, P., Prouza, M., Quel, E. J., Rautenberg, J., Ravel, O., Ravignani, D., Redondo, A., Revenu, B., Rezende, F. A. S., Ridky, J., Riggi, S., Risse, M., Rivière, C., Rizi, V., Robledo, C., Rodriguez, G., Martino, J. Rodriguez, Rojo, J. Rodriguez, Rodriguez-Cabo, I., Rodríguez-Frías, M. D., Ros, G., Rosado, J., Rossler, T., Roth, M., Rouillé-d'Orfeuil, B., Roulet, E., Rovero, A. C., Salamida, F., Salazar, H., Salina, G., Sánchez, F., Santander, M., Santo, C. E., Santos, E. M., Sarazin, F., Sarkar, S., Sato, R., Scharf, N., Scherini, V., Schieler, H., Schiffer, P., Schmidt, A., Schmidt, F., Schmidt, T., Scholten, O., Schoorlemmer, H., Schovancova, J., Schovánek, P., Schroeder, F., Schulte, S., Schüssler, F., Schuster, D., Sciutto, S. J., Scuderi, M., Segreto, A., Semikoz, D., Settimo, M., Shellard, R. C., Sidelnik, I., Siffert, B. B., Sigl, G., Śmiałkowski, A., Šmída, R., Smith, B. E., Snow, G. R., Sommers, P., Sorokin, J., Spinka, H., Squartini, R., Strazzeri, E., Stutz, A., Suarez, F., Suomijärvi, T., Supanitsky, A. D., Sutherland, M. S., Swain, J., Szadkowski, Z., Tamashiro, A., Tamburro, A., Tarutina, T., Taşcău, O., Tcaciuc, R., Tcherniakhovski, D., Tegolo, D., Thao, N. T., Thomas, D., Ticona, R., Tiffenberg, J., Timmermans, C., Tkaczyk, W., Peixoto, C. J. Todero, Tomé, B., Tonachini, A., Torres, I., Travnicek, P., Tridapalli, D. B., Tristram, G., Trovato, E., Tueros, M., Ulrich, R., Unger, M., Urban, M., Galicia, J. F. Valdés, Valiño, I., Valore, L., vandenBerg, A. M., Vázquez, J. R., Vázquez, R. A., Veberič, D., Velarde, A., Venters, T., Verzi, V., Videla, M., Villaseñor, L., Vorobiov, S., Voyvodic, L., Wahlberg, H., Wahrlich, P., Wainberg, O., Warner, D., Watson, A. A., Westerhoff, S., Whelan, B. J., Wieczorek, G., Wiencke, L., Wilczyńska, B., Wilczyński, H., Wileman, C., Winnick, M. G., Wu, H., Wundheiler, B., Yamamoto, T., Younk, P., Yuan, G., Yushkov, A., Zas, E., Zavrtanik, D., Zavrtanik, M., Zaw, I., Zepeda, A., and Ziolkowski, M.

Subjects
Astrophysics - High Energy Astrophysical Phenomena, Astrophysics - Cosmology and Extragalactic Astrophysics
Abstract

Studies of the correlations of ultra-high energy cosmic ray directions with extra-Galactic objects, of general anisotropy, of photons and neutrinos, and of other astrophysical effects, with the Pierre Auger Observatory. Contributions to the 31st ICRC, Lodz, Poland, July 2009., Comment: Submissions to the 31st International Cosmic Ray Conference, Lodz, Poland, July 2009

Published
2009

18. Studies of Cosmic Ray Composition and Air Shower Structure with the Pierre Auger Observatory

Author

The Pierre Auger Collaboration, Abraham, J., Abreu, P., Aglietta, M., Aguirre, C., Ahn, E. J., Allard, D., Allekotte, I., Allen, J., Alvarez-Muñiz, J., Ambrosio, M., Anchordoqui, L., Andringa, S., Anzalone, A., Aramo, C., Arganda, E., Argirò, S., Arisaka, K., Arneodo, F., Arqueros, F., Asch, T., Asorey, H., Assis, P., Aublin, J., Ave, M., Avila, G., Bäcker, T., Badagnani, D., Barber, K. B., Barbosa, A. F., Barroso, S. L. C., Baughman, B., Bauleo, P., Beatty, J. J., Beau, T., Becker, B. R., Becker, K. H., Bellétoile, A., Bellido, J. A., BenZvi, S., Berat, C., Bernardini, P., Bertou, X., Biermann, P. L., Billoir, P., Blanch-Bigas, O., Blanco, F., Bleve, C., Blümer, H., Boháčová, M., Boncioli, D., Bonifazi, C., Bonino, R., Borodai, N., Brack, J., Brogueira, P., Brown, W. C., Bruijn, R., Buchholz, P., Bueno, A., Burton, R. E., Busca, N. G., Caballero-Mora, K. S., Caramete, L., Caruso, R., Carvalho, W., Castellina, A., Catalano, O., Cazon, L., Cester, R., Chauvin, J., Chiavassa, A., Chinellato, J. A., Chou, A., Chudoba, J., Chye, J., Clay, R. W., Colombo, E., Conceição, R., Connolly, B., Contreras, F., Coppens, J., Cordier, A., Cotti, U., Coutu, S., Covault, C. E., Creusot, A., Criss, A., Cronin, J., Curutiu, A., Dagoret-Campagne, S., Dallier, R., Daumiller, K., Dawson, B. R., de Almeida, R. M., De Domenico, M., De Donato, C., de Jong, S. J., De La Vega, G., Junior, W. J. M. de Mello, Neto, J. R. T. de Mello, De Mitri, I., de Souza, V., de Vries, K. D., Decerprit, G., del Peral, L., Deligny, O., Della Selva, A., Fratte, C. Delle, Dembinski, H., DiGiulio, C., Diaz, J. C., Diep, P. N., Dobrigkeit, C., D'Olivo, J. C., Dong, P. N., Dorofeev, A., Anjos, J. C. dos, Dova, M. T., D'Urso, D., Dutan, I., DuVernois, M. A., Engel, R., Erdmann, M., Escobar, C. O., Etchegoyen, A., Luis, P. Facal San, Falcke, H., Farrar, G., Fauth, A. C., Fazzini, N., Ferrer, F., Ferrero, A., Fick, B., Filevich, A., Filipčič, A., Fleck, I., Fliescher, S., Fracchiolla, C. E., Fraenkel, E. D., Fulgione, W., Gamarra, R. F., Gambetta, S., García, B., GarcíaGámez, D., Garcia-Pinto, D., Garrido, X., Gelmini, G., Gemmeke, H., Ghia, P. L., Giaccari, U., Giller, M., Glass, H., Goggin, L. M., Gold, M. S., Golup, G., Albarracin, F. Gomez, Berisso, M. Gómez, Gonçalves, P., Amaral, M. Gonçalves do, Gonzalez, D., Gonzalez, J. G., Góra, D., Gorgi, A., Gouffon, P., Gozzini, S. R., Grashorn, E., Grebe, S., Grigat, M., Grillo, A. F., Guardincerri, Y., Guarino, F., Guedes, G. P., Gutiérrez, J., Hague, J. D., Halenka, V., Hansen, P., Harari, D., Harmsma, S., Harton, J. L., Haungs, A., Healy, M. D., Hebbeker, T., Hebrero, G., Heck, D., Hojvat, C., Holmes, V. C., Homola, P., Hörandel, J. R., Horneffer, A., Hrabovský, M., Huege, T., Hussain, M., Iarlori, M., Insolia, A., Ionita, F., Italiano, A., Jiraskova, S., Kaducak, M., Kampert, K. H., Karova, T., Kasper, P., Kégl, B., Keilhauer, B., Kemp, E., Kieckhafer, R. M., Klages, H. O., Kleifges, M., Kleinfeller, J., Knapik, R., Knapp, J., Koang, D. -H., Krieger, A., Krömer, O., Kruppke-Hansen, D., Kuehn, F., Kuempel, D., Kulbartz, K., Kunka, N., Kusenko, A., LaRosa, G., Lachaud, C., Lago, B. L., Lautridou, P., Leão, M. S. A. B., Lebrun, D., Lebrun, P., Lee, J., de Oliveira, M. A. Leigui, Lemiere, A., Letessier-Selvon, A., Leuthold, M., Lhenry-Yvon, I., López, R., Agüera, A. Lopez, Louedec, K., Bahilo, J. Lozano, Lucero, A., Lyberis, H., Maccarone, M. C., Macolino, C., Maldera, S., Mandat, D., Mantsch, P., Mariazzi, A. G., Maris, I. C., Falcon, H. R. Marquez, Martello, D., Bravo, O. Martínez, Mathes, H. J., Matthews, J., Matthews, J. A. J., Matthiae, G., Maurizio, D., Mazur, P. O., McEwen, M., McNeil, R. R., Medina-Tanco, G., Melissas, M., Melo, D., Menichetti, E., Menshikov, A., Meyhandan, R., Micheletti, M. I., Miele, G., Miller, W., Miramonti, L., Mollerach, S., Monasor, M., Ragaigne, D. Monnier, Montanet, F., Morales, B., Morello, C., Moreno, J. C., Morris, C., Mostafá, M., Moura, C. A., Mueller, S., Muller, M. A., Mussa, R., Navarra, G., Navarro, J. L., Navas, S., Necesal, P., Nellen, L., Newman-Holmes, C., Newton, D., Nhung, P. T., Nierstenhoefer, N., Nitz, D., Nosek, D., Nožka, L., Nyklicek, M., Oehlschläger, J., Olinto, A., Oliva, P., Olmos-Gilbaja, V. M., Ortiz, M., Pacheco, N., Selmi-Dei, D. Pakk, Palatka, M., Pallotta, J., Parente, G., Parizot, E., Parlati, S., Pastor, S., Patel, M., Paul, T., Pavlidou, V., Payet, K., Pech, M., Pȩkala, J., Pepe, I. M., Perrone, L., Pesce, R., Petermann, E., Petrera, S., Petrinca, P., Petrolini, A., Petrov, Y., Petrovic, J., Pfendner, C., Piegaia, R., Pierog, T., Pimenta, M., Pinto, T., Pirronello, V., Pisanti, O., Platino, M., Pochon, J., Ponce, V. H., Pontz, M., Privitera, P., Prouza, M., Quel, E. J., Rautenberg, J., Ravel, O., Ravignani, D., Redondo, A., Revenu, B., Rezende, F. A. S., Ridky, J., Riggi, S., Risse, M., Rivière, C., Rizi, V., Robledo, C., Rodriguez, G., Martino, J. Rodriguez, Rojo, J. Rodriguez, Rodriguez-Cabo, I., Rodríguez-Frías, M. D., Ros, G., Rosado, J., Rossler, T., Roth, M., Rouillé-d'Orfeuil, B., Roulet, E., Rovero, A. C., Salamida, F., Salazar, H., Salina, G., Sánchez, F., Santander, M., Santo, C. E., Santos, E. M., Sarazin, F., Sarkar, S., Sato, R., Scharf, N., Scherini, V., Schieler, H., Schiffer, P., Schmidt, A., Schmidt, F., Schmidt, T., Scholten, O., Schoorlemmer, H., Schovancova, J., Schovánek, P., Schroeder, F., Schulte, S., Schüssler, F., Schuster, D., Sciutto, S. J., Scuderi, M., Segreto, A., Semikoz, D., Settimo, M., Shellard, R. C., Sidelnik, I., Siffert, B. B., Sigl, G., Śmiałkowski, A., Šmída, R., Smith, B. E., Snow, G. R., Sommers, P., Sorokin, J., Spinka, H., Squartini, R., Strazzeri, E., Stutz, A., Suarez, F., Suomijärvi, T., Supanitsky, A. D., Sutherland, M. S., Swain, J., Szadkowski, Z., Tamashiro, A., Tamburro, A., Tarutina, T., Taşcău, O., Tcaciuc, R., Tcherniakhovski, D., Tegolo, D., Thao, N. T., Thomas, D., Ticona, R., Tiffenberg, J., Timmermans, C., Tkaczyk, W., Peixoto, C. J. Todero, Tomé, B., Tonachini, A., Torres, I., Travnicek, P., Tridapalli, D. B., Tristram, G., Trovato, E., Tueros, M., Ulrich, R., Unger, M., Urban, M., Galicia, J. F. Valdés, Valiño, I., Valore, L., vandenBerg, A. M., Vázquez, J. R., Vázquez, R. A., Veberič, D., Velarde, A., Venters, T., Verzi, V., Videla, M., Villaseñor, L., Vorobiov, S., Voyvodic, L., Wahlberg, H., Wahrlich, P., Wainberg, O., Warner, D., Watson, A. A., Westerhoff, S., Whelan, B. J., Wieczorek, G., Wiencke, L., Wilczyńska, B., Wilczyński, H., Wileman, C., Winnick, M. G., Wu, H., Wundheiler, B., Yamamoto, T., Younk, P., Yuan, G., Yushkov, A., Zas, E., Zavrtanik, D., Zavrtanik, M., Zaw, I., Zepeda, A., and Ziolkowski, M.

Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics, Astrophysics - High Energy Astrophysical Phenomena
Abstract

Studies of the composition of the highest energy cosmic rays with the Pierre Auger Observatory, including examination of hadronic physics effects on the structure of extensive air showers. Submissions to the 31st ICRC, Lodz, Poland (July 2009)., Comment: Submissions to the 31st International Cosmic Ray Conference, Lodz, Poland (July 2009)

Published
2009

19. The Cosmic Ray Energy Spectrum and Related Measurements with the Pierre Auger Observatory

Author

The Pierre Auger Collaboration, Abraham, J., Abreu, P., Aglietta, M., Aguirre, C., Ahn, E. J., Allard, D., Allekotte, I., Allen, J., Alvarez-Muñiz, J., Ambrosio, M., Anchordoqui, L., Andringa, S., Anzalone, A., Aramo, C., Arganda, E., Argirò, S., Arisaka, K., Arneodo, F., Arqueros, F., Asch, T., Asorey, H., Assis, P., Aublin, J., Ave, M., Avila, G., Bäcker, T., Badagnani, D., Barber, K. B., Barbosa, A. F., Barroso, S. L. C., Baughman, B., Bauleo, P., Beatty, J. J., Beau, T., Becker, B. R., Becker, K. H., Bellétoile, A., Bellido, J. A., BenZvi, S., Berat, C., Bernardini, P., Bertou, X., Biermann, P. L., Billoir, P., Blanch-Bigas, O., Blanco, F., Bleve, C., Blümer, H., Boháčová, M., Boncioli, D., Bonifazi, C., Bonino, R., Borodai, N., Brack, J., Brogueira, P., Brown, W. C., Bruijn, R., Buchholz, P., Bueno, A., Burton, R. E., Busca, N. G., Caballero-Mora, K. S., Caramete, L., Caruso, R., Carvalho, W., Castellina, A., Catalano, O., Cazon, L., Cester, R., Chauvin, J., Chiavassa, A., Chinellato, J. A., Chou, A., Chudoba, J., Chye, J., Clay, R. W., Colombo, E., Conceição, R., Connolly, B., Contreras, F., Coppens, J., Cordier, A., Cotti, U., Coutu, S., Covault, C. E., Creusot, A., Criss, A., Cronin, J., Curutiu, A., Dagoret-Campagne, S., Dallier, R., Daumiller, K., Dawson, B. R., de Almeida, R. M., De Domenico, M., De Donato, C., de Jong, S. J., De La Vega, G., Junior, W. J. M. de Mello, Neto, J. R. T. de Mello, De Mitri, I., de Souza, V., de Vries, K. D., Decerprit, G., del Peral, L., Deligny, O., Della Selva, A., Fratte, C. Delle, Dembinski, H., DiGiulio, C., Diaz, J. C., Diep, P. N., Dobrigkeit, C., D'Olivo, J. C., Dong, P. N., Dorofeev, A., Anjos, J. C. dos, Dova, M. T., D'Urso, D., Dutan, I., DuVernois, M. A., Engel, R., Erdmann, M., Escobar, C. O., Etchegoyen, A., Luis, P. Facal San, Falcke, H., Farrar, G., Fauth, A. C., Fazzini, N., Ferrer, F., Ferrero, A., Fick, B., Filevich, A., Filipčič, A., Fleck, I., Fliescher, S., Fracchiolla, C. E., Fraenkel, E. D., Fulgione, W., Gamarra, R. F., Gambetta, S., García, B., GarcíaGámez, D., Garcia-Pinto, D., Garrido, X., Gelmini, G., Gemmeke, H., Ghia, P. L., Giaccari, U., Giller, M., Glass, H., Goggin, L. M., Gold, M. S., Golup, G., Albarracin, F. Gomez, Berisso, M. Gómez, Gonçalves, P., Amaral, M. Gonçalves do, Gonzalez, D., Gonzalez, J. G., Góra, D., Gorgi, A., Gouffon, P., Gozzini, S. R., Grashorn, E., Grebe, S., Grigat, M., Grillo, A. F., Guardincerri, Y., Guarino, F., Guedes, G. P., Gutiérrez, J., Hague, J. D., Halenka, V., Hansen, P., Harari, D., Harmsma, S., Harton, J. L., Haungs, A., Healy, M. D., Hebbeker, T., Hebrero, G., Heck, D., Holmes, V. C., Homola, P., Hörandel, J. R., Horneffer, A., Hrabovský, M., Huege, T., Hussain, M., Iarlori, M., Insolia, A., Ionita, F., Italiano, A., Jiraskova, S., Kaducak, M., Kampert, K. H., Karova, T., Kasper, P., Kégl, B., Keilhauer, B., Kemp, E., Kieckhafer, R. M., Klages, H. O., Kleifges, M., Kleinfeller, J., Knapik, R., Knapp, J., Koang, D. -H., Krieger, A., Krömer, O., Kruppke-Hansen, D., Kuehn, F., Kuempel, D., Kulbartz, K., Kunka, N., Kusenko, A., LaRosa, G., Lachaud, C., Lago, B. L., Lautridou, P., Leão, M. S. A. B., Lebrun, D., Lebrun, P., Lee, J., de Oliveira, M. A. Leigui, Lemiere, A., Letessier-Selvon, A., Leuthold, M., Lhenry-Yvon, I., López, R., Agüera, A. Lopez, Louedec, K., Bahilo, J. Lozano, Lucero, A., Lyberis, H., Maccarone, M. C., Macolino, C., Maldera, S., Mandat, D., Mantsch, P., Mariazzi, A. G., Maris, I. C., Falcon, H. R. Marquez, Martello, D., Bravo, O. Martínez, Mathes, H. J., Matthews, J., Matthews, J. A. J., Matthiae, G., Maurizio, D., Mazur, P. O., McEwen, M., McNeil, R. R., Medina-Tanco, G., Melissas, M., Melo, D., Menichetti, E., Menshikov, A., Meyhandan, R., Micheletti, M. I., Miele, G., Miller, W., Miramonti, L., Mollerach, S., Monasor, M., Ragaigne, D. Monnier, Montanet, F., Morales, B., Morello, C., Moreno, J. C., Morris, C., Mostafá, M., Moura, C. A., Mueller, S., Muller, M. A., Mussa, R., Navarra, G., Navarro, J. L., Navas, S., Necesal, P., Nellen, L., Newman-Holmes, C., Newton, D., Nhung, P. T., Nierstenhoefer, N., Nitz, D., Nosek, D., Nožka, L., Nyklicek, M., Oehlschläger, J., Olinto, A., Oliva, P., Olmos-Gilbaja, V. M., Ortiz, M., Pacheco, N., Selmi-Dei, D. Pakk, Palatka, M., Pallotta, J., Parente, G., Parizot, E., Parlati, S., Pastor, S., Patel, M., Paul, T., Pavlidou, V., Payet, K., Pech, M., Pȩkala, J., Pepe, I. M., Perrone, L., Pesce, R., Petermann, E., Petrera, S., Petrinca, P., Petrolini, A., Petrov, Y., Petrovic, J., Pfendner, C., Piegaia, R., Pierog, T., Pimenta, M., Pinto, T., Pirronello, V., Pisanti, O., Platino, M., Pochon, J., Ponce, V. H., Pontz, M., Privitera, P., Prouza, M., Quel, E. J., Rautenberg, J., Ravel, O., Ravignani, D., Redondo, A., Revenu, B., Rezende, F. A. S., Ridky, J., Riggi, S., Risse, M., Rivière, C., Rizi, V., Robledo, C., Rodriguez, G., Martino, J. Rodriguez, Rojo, J. Rodriguez, Rodriguez-Cabo, I., Rodríguez-Frías, M. D., Ros, G., Rosado, J., Rossler, T., Roth, M., Rouillé-d'Orfeuil, B., Roulet, E., Rovero, A. C., Salamida, F., Salazar, H., Salina, G., Sánchez, F., Santander, M., Santo, C. E., Santos, E. M., Sarazin, F., Sarkar, S., Sato, R., Scharf, N., Scherini, V., Schieler, H., Schiffer, P., Schmidt, A., Schmidt, F., Schmidt, T., Scholten, O., Schoorlemmer, H., Schovancova, J., Schovánek, P., Schroeder, F., Schulte, S., Schüssler, F., Schuster, D., Sciutto, S. J., Scuderi, M., Segreto, A., Semikoz, D., Settimo, M., Shellard, R. C., Sidelnik, I., Siffert, B. B., Sigl, G., Śmiałkowski, A., Šmída, R., Smith, B. E., Snow, G. R., Sommers, P., Sorokin, J., Spinka, H., Squartini, R., Strazzeri, E., Stutz, A., Suarez, F., Suomijärvi, T., Supanitsky, A. D., Sutherland, M. S., Swain, J., Szadkowski, Z., Tamashiro, A., Tamburro, A., Tarutina, T., Taşcău, O., Tcaciuc, R., Tcherniakhovski, D., Tegolo, D., Thao, N. T., Thomas, D., Ticona, R., Tiffenberg, J., Timmermans, C., Tkaczyk, W., Peixoto, C. J. Todero, Tomé, B., Tonachini, A., Torres, I., Travnicek, P., Tridapalli, D. B., Tristram, G., Trovato, E., Tueros, M., Ulrich, R., Unger, M., Urban, M., Galicia, J. F. Valdés, Valiño, I., Valore, L., vandenBerg, A. M., Vázquez, J. R., Vázquez, R. A., Veberič, D., Velarde, A., Venters, T., Verzi, V., Videla, M., Villaseñor, L., Vorobiov, S., Voyvodic, L., Wahlberg, H., Wahrlich, P., Wainberg, O., Warner, D., Watson, A. A., Westerhoff, S., Whelan, B. J., Wieczorek, G., Wiencke, L., Wilczyńska, B., Wilczyński, H., Wileman, C., Winnick, M. G., Wu, H., Wundheiler, B., Yamamoto, T., Younk, P., Yuan, G., Yushkov, A., Zas, E., Zavrtanik, D., Zavrtanik, M., Zaw, I., Zepeda, A., and Ziolkowski, M.

Subjects
Astrophysics - High Energy Astrophysical Phenomena
Abstract

Studies of the cosmic ray energy spectrum at the highest energies with the Pierre Auger Observatory., Comment: Submissions to the 31st International Cosmic Ray Conference

Published
2009

20. Upper limit on the cosmic-ray photon fraction at EeV energies from the Pierre Auger Observatory

Author

The Pierre Auger Collaboration, Abraham, J., Abreu, P., Aglietta, M., Aguirre, C., Ahn, E. J., Allard, D., Allekotte, I., Allen, J., Allison, P., Alvarez-Muñiz, J., Ambrosio, M., Anchordoqui, L., Andringa, S., Anzalone, A., Aramo, C., Argiró, S., Arisaka, K., Arneodo, F., Arqueros, F., Asch, T., Asorey, H., Assis, P., Aublin, J., Ave, M., Avila, G., Bäcker, T., Badagnani, D., Barber, K. B., Barbosa, A. F., Barroso, S. L. C., Baughman, B., Bauleo, P., Beatty, J. J., Beau, T., Becker, B. R., Becker, K. H., Bellétoile, A., Bellido, J. A., BenZvi, S., Berat, C., Bernardini, P., Bertou, X., Biermann, P. L., Billoir, P., Blanch-Bigas, O., Blanco, F., Bleve, C., Blümer, H., Boháčová, M., Bonifazi, C., Bonino, R., Brack, J., Brogueira, P., Brown, W. C., Bruijn, R., Buchholz, P., Bueno, A., Burton, R. E., Busca, N. G., Caballero-Mora, K. S., Caramete, L., Caruso, R., Carvalho, W., Castellina, A., Catalano, O., Cazon, L., Cester, R., Chauvin, J., Chiavassa, A., Chinellato, J. A., Chou, A., Chudoba, J., Chye, J., Clay, R. W., Colombo, E., Conceição, R., Connolly, B., Contreras, F., Coppens, J., Cordier, A., Cotti, U., Coutu, S., Covault, C. E., Creusot, A., Criss, A., Cronin, J., Curutiu, A., Dagoret-Campagne, S., Daumiller, K., Dawson, B. R., de Almeida, R. M., De Domenico, M., De Donato, C., de Jong, S. J., De La Vega, G., Junior, W. J. M. de Mello, Neto, J. R. T. de Mello, De Mitri, I., de Souza, V., Decerprit, G., del Peral, L., Deligny, O., Della Selva, A., Fratte, C. Delle, Dembinski, H., Di Giulio, C., Diaz, J. C., Diep, P. N., Dobrigkeit, C., D'Olivo, J. C., Dong, P. N., Dornic, D., Dorofeev, A., Anjos, J. C. dos, Dova, M. T., D'Urso, D., Dutan, I., DuVernois, M. A., Engel, R., Erdmann, M., Escobar, C. O., Etchegoyen, A., Luis, P. Facal San, Falcke, H., Farrar, G., Fauth, A. C., Fazzini, N., Ferrer, F., Ferrero, A., Fick, B., Filevich, A., Filipçiç, A., Fleck, I., Fliescher, S., Fracchiolla, C. E., Fraenkel, E. D., Fulgione, W., Gamarra, R. F., Gambetta, S., García, B., Gámez, D. García, Garcia-Pinto, D., Garrido, X., Gelmini, G., Gemmeke, H., Ghia, P. L., Giaccari, U., Giller, M., Glass, H., Goggin, L. M., Gold, M. S., Golup, G., Albarracin, F. Gomez, Berisso, M. Gómez, Gonçalves, P., Amaral, M. Gonçalves do, Gonzalez, D., Gonzalez, J. G., Góra, D., Gorgi, A., Gouffon, P., Grebe, S., Grigat, M., Grillo, A. F., Guardincerri, Y., Guarino, F., Guedes, G. P., Gutiérrez, J., Hague, J. D., Halenka, V., Hansen, P., Harari, D., Harmsma, S., Harton, J. L., Haungs, A., Healy, M. D., Hebbeker, T., Hebrero, G., Heck, D., Hojvat, C., Holmes, V. C., Homola, P., Hörandel, J. R., Horneffer, A., Hrabovský, M., Huege, T., Hussain, M., Iarlori, M., Insolia, A., Ionita, F., Italiano, A., Jiraskova, S., Kaducak, M., Kampert, K. H., Karova, T., Kasper, P., Kégl, B., Keilhauer, B., Kemp, E., Kieckhafer, R. M., Klages, H. O., Kleifges, M., Kleinfeller, J., Knapik, R., Knapp, J., Koang, D. -H., Krieger, A., Krömer, O., Kruppke, D., Kuempel, D., Kunka, N., Kusenko, A., La Rosa, G., Lachaud, C., Lago, B. L., Leão, M. S. A. B., Lebrun, D., Lebrun, P., Lee, J., de Oliveira, M. A. Leigui, Lemiere, A., Letessier-Selvon, A., Leuthold, M., Lhenry-Yvon, I., López, R., Agüera, A. Lopez, Bahilo, J. Lozano, Lucero, A., García, R. Luna, Maccarone, M. C., Macolino, C., Maldera, S., Mandat, D., Mantsch, P., Mariazzi, A. G., Maris, I. C., Falcon, H. R. Marquez, Martello, D., Martínez, J., Bravo, O. Martínez, Mathes, H. J., Matthews, J., Matthews, J. A. J., Matthiae, G., Maurizio, D., Mazur, P. O., McEwen, M., McNeil, R. R., Medina-Tanco, G., Melissas, M., Melo, D., Menichetti, E., Menshikov, A., Meyhandan, R., Micheletti, M. I., Miele, G., Miller, W., Miramonti, L., Mollerach, S., Monasor, M., Ragaigne, D. Monnier, Montanet, F., Morales, B., Morello, C., Moreno, J. C., Morris, C., Mostafá, M., Mueller, S., Muller, M. A., Mussa, R., Navarra, G., Navarro, J. L., Navas, S., Necesal, P., Nellen, L., Newman-Holmes, C., Newton, D., Nhung, P. T., Nierstenhoefer, N., Nitz, D., Nosek, D., Nožka, L., Oehlschläger, J., Olinto, A., Olmos-Gilbaja, V. M., Ortiz, M., Ortolani, F., Pacheco, N., Selmi-Dei, D. Pakk, Palatka, M., Pallotta, J., Parente, G., Parizot, E., Parlati, S., Pastor, S., Patel, M., Paul, T., Pavlidou, V., Payet, K., Pech, M., Pȩkala, J., Pelayo, R., Pepe, I. M., Perrone, L., Pesce, R., Petermann, E., Petrera, S., Petrinca, P., Petrolini, A., Petrov, Y., Petrovic, J., Pfendner, C., Pichel, A., Piegaia, R., Pierog, T., Pimenta, M., into, T. P, Pirronello, V., Pisanti, O., Platino, M., Pochon, J., Ponce, V. H., Pontz, M., Privitera, P., Prouza, M., Quel, E. J., Rautenberg, J., Ravignani, D., Redondo, A., Reucroft, S., Revenu, B., Rezende, F. A. S., Ridky, J., Riggi, S., Risse, M., Riviére, C., Rizi, V., Robledo, C., Rodriguez, G., Martino, J. Rodriguez, Rojo, J. Rodriguez, Rodriguez-Cabo, I., Rodríguez-Frías, M. D., Ros, G., Rosado, J., Roth, M., Rouillé-d'Orfeuil, B., Roulet, E., Rovero, A. C., Salamida, F., Salazar, H., Salina, G., Sánchez, F., Santander, M., Santo, C. E., Santos, E. M., Sarazin, F., Sarkar, S., Sato, R., Scharf, N., Scherini, V., Schieler, H., Schiffer, P., Schmidt, A., Schmidt, F., Schmidt, T., Scholten, O., Schoorlemmer, H., Schovancova, J., Schovánek, P., Schroeder, F., Schulte, S., Schüssler, F., Schuster, D., Sciutto, S. J., Scuderi, M., Segreto, A., Semikoz, D., Settimo, M., Shellard, R. C., Sidelnik, I., Siffert, B. B., De Grande, N. Smetniansky, Smiałkowski, A., Šmída, R., Smith, B. E., Snow, G. R., Sommers, P., Sorokin, J., Spinka, H., Squartini, R., Strazzeri, E., Stutz, A., Suarez, F., Suomijärvi, T., Supanitsky, A. D., Sutherland, M. S., Swain, J., Szadkowski, Z., Tamashiro, A., Tamburro, A., Tarutina, T., Taşcǎu, O., Tcaciuc, R., Tcherniakhovski, D., Thao, N. T., Thomas, D., Ticona, R., Tiffenberg, J., Timmermans, C., Tkaczyk, W., Peixoto, C. J. Todero, Tomé, B., Tonachini, A., Torres, I., Travnicek, P., Tridapalli, D. B., Tristram, G., Trovato, E., Tuci, V., Tueros, M., Ulrich, R., Unger, M., Urban, M., Galicia, J. F. Valdés, Valiño, I., Valore, L., Berg, A. M. van den, Vázquez, R. A., Veberič, D., Velarde, A., Venters, T., Verzi, V., Videla, M., Villaseñor, L., Vorobiov, S., Voyvodic, L., Wahlberg, H., Wahrlich, P., Wainberg, O., Warner, D., Watson, A. A., Westerhoff, S., Whelan, B. J., Wieczorek, G., Wiencke, L., Wilczyńska, B., Wilczyński, H., Wileman, C., Winnick, M. G., Wu, H., Wundheiler, B., Younk, P., Yuan, G., Zas, E., Zavrtanik, D., Zavrtanik, M., Zaw, I., Zepeda, A., and Ziolkowski, M.

Subjects
Astrophysics - High Energy Astrophysical Phenomena
Abstract

From direct observations of the longitudinal development of ultra-high energy air showers performed with the Pierre Auger Observatory, upper limits of 3.8%, 2.4%, 3.5% and 11.7% (at 95% c.l.) are obtained on the fraction of cosmic-ray photons above 2, 3, 5 and 10 EeV (1 EeV = 10^18 eV) respectively. These are the first experimental limits on ultra-high energy photons at energies below 10 EeV. The results complement previous constraints on top-down models from array data and they reduce systematic uncertainties in the interpretation of shower data in terms of primary flux, nuclear composition and proton-air cross-section., Comment: 20 pages, 7 figures, 2 tables. Minor changes. Accepted by Astroparticle Physics

Published
2009
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23. Validation of a highly accelerated post-contrast wave-controlled aliasing in parallel imaging (CAIPI) 3D-T1 MPRAGE compared to standard 3D-T1 MPRAGE for detection of intracranial enhancing lesions on 3-T MRI

Author

Augusto Lio M, Goncalves Filho, Komal Manzoor, Awan, John, Conklin, Chanon, Ngamsombat, Stephen F, Cauley, Kawin, Setsompop, Wei, Liu, Daniel N, Splitthoff, Wei-Ching, Lo, John E, Kirsch, Pamela W, Schaefer, Otto, Rapalino, and Susie Y, Huang

Subjects
Radiology, Nuclear Medicine and imaging, General Medicine
Abstract

High-resolution post-contrast T1-weighted imaging is a workhorse sequence in the evaluation of neurological disorders. The T1-MPRAGE sequence has been widely adopted for the visualization of enhancing pathology in the brain. However, this three-dimensional (3D) acquisition is lengthy and prone to motion artifact, which often compromises diagnostic quality. The goal of this study was to compare a highly accelerated wave-controlled aliasing in parallel imaging (CAIPI) post-contrast 3D T1-MPRAGE sequence (Wave-T1-MPRAGE) with the standard 3D T1-MPRAGE sequence for visualizing enhancing lesions in brain imaging at 3 T.This study included 80 patients undergoing contrast-enhanced brain MRI. The participants were scanned with a standard post-contrast T1-MPRAGE sequence (acceleration factor [R] = 2 using GRAPPA parallel imaging technique, acquisition time [TA] = 5 min 18 s) and a prototype post-contrast Wave-T1-MPRAGE sequence (R = 4, TA = 2 min 32 s). Two neuroradiologists performed a head-to-head evaluation of both sequences and rated the visualization of enhancement, sharpness, noise, motion artifacts, and overall diagnostic quality. A 15% noninferiority margin was used to test whether post-contrast Wave-T1-MPRAGE was noninferior to standard T1-MPRAGE. Inter-rater and intra-rater agreement were calculated. Quantitative assessment of CNR/SNR was performed.Wave-T1-MPRAGE was noninferior to standard T1-MPRAGE for delineating enhancing lesions with unanimous agreement in all cases between raters. Wave-T1-MPRAGE was noninferior in the perception of noise (p0.001), motion artifact (p0.001), and overall diagnostic quality (p0.001).High-accelerated post-contrast Wave-T1-MPRAGE enabled a two-fold reduction in acquisition time compared to the standard sequence with comparable performance for visualization of enhancing pathology and equivalent perception of noise, motion artifacts and overall diagnostic quality without loss of clinically important information.• Post-contrast wave-controlled aliasing in parallel imaging (CAIPI) T1-MPRAGE accelerated the acquisition of three-dimensional (3D) high-resolution post-contrast images by more than two-fold. • Post-contrast Wave-T1-MPRAGE was noninferior to standard T1-MPRAGE with unanimous agreement between reviewers (100% in 80 cases) for the visualization of intracranial enhancing lesions. • Wave-T1-MPRAGE was equivalent to the standard sequence in the perception of noise in 94% (75 of 80) of cases and was preferred in 16% (13 of 80) of cases for decreased motion artifact.

Published
2022
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24. iPSC: HUMAN IPSC ORGANOID PRODUCTION FOR PATIENT-SPECIFIC LIVER BIOFABRICATION

Author

Martins-Santos, R., primary, Rodrigues, K.M., additional, Oliveira, J., additional, Paranhos, B.A., additional, Amorim, É., additional, de Leiros Ferreira, J. Pereira, additional, Barbosa Freire, G. Roldão, additional, Mitrach, M., additional, de Souza, M. Goncalves, additional, Condorelli, L. Bettencourt, additional, Batista, L., additional, and Goldenberg, R., additional

Published
2023
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28. Insomnia and nightmare profiles during the COVID-19 pandemic in Portugal: characterization and associated factors

Author

M. Goncalves, A. Henriques, A.R. Costa, D. Correia, M. Severo, R. Lucas, H. Barros, Ana Cristina Santos, Ana Isabel Ribeiro, Artur Rocha, Carla Lopes, Daniela Correia, Elisabete Ramos, Gonçalo Gonçalves, Henrique Barros, Joana Araújo, Makram Talih, Margarida Tavares, Milton Severo, Nuno Lunet, Paula Meireles, Raquel Duarte, Raquel Lucas, Rui Camacho, Sílvia Fraga, Sofia Correia, Susana Silva, and Teresa Leão

Subjects
Portugal, SARS-CoV-2, COVID-19, General Medicine, Dreams, Cohort Studies, Nightmares, Sleep Initiation and Maintenance Disorders, Communicable Disease Control, Insomnia symptoms, Humans, Female, Original Article, Pandemics, Prospective studies
Abstract

Objective/background To describe and characterize insomnia symptoms and nightmare profiles in Portugal during the first six weeks of a national lockdown due to COVID-19. Patients/methods An open cohort study was conducted to collect information of the general population during the first wave of SARS-CoV-2/COVID-19 pandemic in Portugal. We analyzed data from 5011 participants (≥16 years) who answered a weekly questionnaire about their well-being. Two questions about the frequency of insomnia and nightmares about COVID-19 were consecutively applied during six weeks (March–May 2020). Latent class analysis was conducted and different insomnia and nightmare profiles were identified. Associations between individual characteristics and both profiles were estimated using odds ratios (ORs) and 95% confidence intervals (CI). Results Five insomnia (No insomnia, Stable-mild, Decreasing-moderate, Stable-severe, Increasing-severe) and three nightmares profiles (Stable-mild, Stable-moderate, Stable-severe) were identified. Being female, younger, perceiving their income as insufficient and feelings of fear towards COVID-19 were associated with higher odds of insomnia (Women: OR = 6.98 95%CI: 4.18–11.64; ≥60 years: OR = 0.30 95%CI: 0.18–0.53; Insufficient income: adjusted OR (aOR) = 8.413 95%CI: 3.93–16.84; Often presenting fear of being infected with SARS-CoV-2 infection: aOR = 9.13 95%CI: 6.36–13.11), and nightmares (Women: OR = 2.60 95%CI: 1.74–3.86; ≥60 years: OR = 0.45 95%CI: 0.28–0.74; Insufficient income: aOR = 2.60 95%CI: 1.20–5.20; Often/almost always presenting fear of being infected with SARS-CoV-2 infection: aOR = 6.62 95%CI: 5.01–8.74). Having a diagnosis of SARS-CoV-2 virus infection was associated with worse patterns of nightmares about the pandemic. Conclusions Social and psychological individual factors are important characteristics to consider in the development of therapeutic strategies to support people with sleep problems during the COVID-19 pandemic.

Published
2022
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29. Blocking CHOP-dependent TXNIP shuttling to mitochondria attenuates albuminuria and mitigates kidney injury in nephrotic syndrome

Author

Sun-Ji Park, Yeawon Kim, Chuang Li, Junwoo Suh, Jothilingam Sivapackiam, Tassia M. Goncalves, George Jarad, Guoyan Zhao, Fumihiko Urano, Vijay Sharma, and Ying Maggie Chen

Subjects
Cell Nucleus, Multidisciplinary, Nephrotic Syndrome, Inflammasomes, Apoptosis, Kidney, MAP Kinase Kinase Kinase 5, Mitochondria, Mitochondrial Proteins, Mice, Thioredoxins, NLR Family, Pyrin Domain-Containing 3 Protein, Albuminuria, Animals, Carrier Proteins, Reactive Oxygen Species, Gene Deletion, Transcription Factor CHOP
Abstract

Albuminuria is a hallmark of glomerular disease of various etiologies. It is not only a symptom of glomerular disease but also a cause leading to glomerulosclerosis, interstitial fibrosis, and eventually, a decline in kidney function. The molecular mechanism underlying albuminuria-induced kidney injury remains poorly defined. In our genetic model of nephrotic syndrome (NS), we have identified CHOP (C/EBP homologous protein)-TXNIP (thioredoxin-interacting protein) as critical molecular linkers between albuminuria-induced ER dysfunction and mitochondria dyshomeostasis. TXNIP is a ubiquitously expressed redox protein that binds to and inhibits antioxidant enzyme, cytosolic thioredoxin 1 (Trx1), and mitochondrial Trx2. However, very little is known about the regulation and function of TXNIP in NS. By utilizing Chop −/− and Txnip −/− mice as well as 68 Ga-Galuminox, our molecular imaging probe for detection of mitochondrial reactive oxygen species (ROS) in vivo, we demonstrate that CHOP up-regulation induced by albuminuria drives TXNIP shuttling from nucleus to mitochondria, where it is required for the induction of mitochondrial ROS. The increased ROS accumulation in mitochondria oxidizes Trx2, thus liberating TXNIP to associate with mitochondrial nod-like receptor protein 3 (NLRP3) to activate inflammasome, as well as releasing mitochondrial apoptosis signal-regulating kinase 1 (ASK1) to induce mitochondria-dependent apoptosis. Importantly, inhibition of TXNIP translocation and mitochondrial ROS overproduction by CHOP deletion suppresses NLRP3 inflammasome activation and p-ASK1–dependent mitochondria apoptosis in NS. Thus, targeting TXNIP represents a promising therapeutic strategy for the treatment of NS.

Published
2023

33. iPSC: HUMAN IPSC ORGANOID PRODUCTION FOR PATIENT-SPECIFIC LIVER BIOFABRICATION

Author

R. Martins-Santos, K.M. Rodrigues, J. Oliveira, B.A. Paranhos, É. Amorim, J. Pereira de Leiros Ferreira, G. Roldão Barbosa Freire, M. Mitrach, M. Goncalves de Souza, L. Bettencourt Condorelli, L. Batista, and R. Goldenberg

Subjects
Cancer Research, Transplantation, Oncology, Immunology, Immunology and Allergy, Cell Biology, Genetics (clinical)
Published
2023
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35. Optimization of magnetization transfer contrast for EPI FLAIR brain imaging

Author

Serdest Demir, Bryan Clifford, Wei‐Ching Lo, Azadeh Tabari, Augusto Lio M. Goncalves Filho, Min Lang, Stephen F. Cauley, Kawin Setsompop, Berkin Bilgic, Michael H. Lev, Pamela W. Schaefer, Otto Rapalino, Susie Y. Huang, Tom Hilbert, Thorsten Feiweier, and John Conklin

Subjects
Echo-Planar Imaging, Brain, Humans, Neuroimaging, Radiology, Nuclear Medicine and imaging, Gray Matter, Magnetic Resonance Imaging, White Matter, Article
Abstract

To evaluate the impact of magnetization transfer (MT) on brain tissue contrast in turbo-spin-echo (TSE) and EPI fluid-attenuated inversion recovery (FLAIR) images, and to optimize an MT-prepared EPI FLAIR pulse sequence to match the tissue contrast of a clinical reference TSE FLAIR protocol.Five healthy volunteers underwent 3T brain MRI, including single slice TSE FLAIR, multi-slice TSE FLAIR, EPI FLAIR without MT-preparation, and MT-prepared EPI FLAIR with variations of the MT-preparation parameters, including number of preparation pulses, pulse amplitude, and resonance offset. Automated co-registration and gray matter (GM) versus white matter (WM) segmentation was performed using a T1-MPRAGE acquisition, and the GM versus WM signal intensity ratio (contrast ratio) was calculated for each FLAIR acquisition.Without MT preparation, EPI FLAIR showed poor tissue contrast (contrast ratio = 0.98), as did single slice TSE FLAIR. Multi-slice TSE FLAIR provided high tissue contrast (contrast ratio = 1.14). MT-prepared EPI FLAIR closely approximated the contrast of the multi-slice TSE FLAIR images for two combinations of the MT-preparation parameters (contrast ratio = 1.14). Optimized MT-prepared EPI FLAIR provided a 50% reduction in scan time compared to the reference TSE FLAIR acquisition.Optimized MT-prepared EPI FLAIR provides comparable brain tissue contrast to the multi-slice TSE FLAIR images used in clinical practice.

Published
2022
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37. An artificial intelligence‐accelerated 2‐minute multi‐shot echo planar imaging protocol for comprehensive high‐quality clinical brain imaging

Author

Bryan Clifford, John Conklin, Susie Y. Huang, Thorsten Feiweier, Zahra Hosseini, Augusto Lio M. Goncalves Filho, Azadeh Tabari, Serdest Demir, Wei‐Ching Lo, Maria Gabriela Figueiro Longo, Michael Lev, Pam Schaefer, Otto Rapalino, Kawin Setsompop, Berkin Bilgic, and Stephen Cauley

Subjects
Diffusion Magnetic Resonance Imaging, Artificial Intelligence, Echo-Planar Imaging, Image Processing, Computer-Assisted, Brain, Humans, Neuroimaging, Radiology, Nuclear Medicine and imaging
Abstract

We introduce and validate an artificial intelligence (AI)-accelerated multi-shot echo-planar imaging (msEPI)-based method that provides T1w, T2w,The rapid imaging technique combines a novel machine learning (ML) scheme to limit g-factor noise amplification and improve SNR, a magnetization transfer preparation module to provide clinically desirable contrast, and high per-shot EPI undersampling factors to reduce distortion. The ML training and image reconstruction incorporates a tunable parameter for controlling the level of denoising/smoothness. The performance of the reconstruction method is evaluated across various acceleration factors, contrasts, and SNR conditions. The 2-minute protocol is directly compared to a 10-minute clinical reference protocol through deployment in a clinical setting, where five representative cases with pathology are examined.Optimization of custom msEPI sequences and protocols was performed to balance acquisition efficiency and image quality compared to the five-fold longer clinical reference. Training data from 16 healthy subjects across multiple contrasts and orientations were used to produce ML networks at various acceleration levels. The flexibility of the ML reconstruction was demonstrated across SNR levels, and an optimized regularization was determined through radiological review. Network generalization toward novel pathology, unobserved during training, was illustrated in five clinical case studies with clinical reference images provided for comparison.The rapid 2-minute msEPI-based protocol with tunable ML reconstruction allows for advantageous trade-offs between acquisition speed, SNR, and tissue contrast when compared to the five-fold slower standard clinical reference exam.

Published
2021
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38. Prediction of gas production rate from shale gas reservoirs using a micro–macro analysis

Author

Dantong Lin, Di Zhang, Xinghao Zhang, Bruno M. Goncalves da Silva, Liming Hu, and Jay N. Meegoda

Subjects
Multidisciplinary
Abstract

Shale gas has become one of the important contributors to the global energy supply. The declining pattern of the gas production rate with time from an unconventional gas reservoir is due to the depletion of shale gas stored in the nanovoids of the shale formation. However, there are only limited ways to predict the variation of the gas production rate with time from an unconventional gas reservoir. This is due to the multiple transport mechanisms of gas in nano-scale pores and changes in shale gas permeability with pressures in nano-scale pores, which is impacted by the pore structure of the shale. In this study, the permeability-pressure (K-p) relationship for different shales (Eagle Ford, Haynesville, Longmaxi and Opalinus) were determined using an equivalent anisotropic pore network model (PNM). This PNM has REV-scale shale gas flow in randomly generated nanovoids and their connection in the shale matrix, and the multiphase flow of shale gas including viscous flow, slip flow and Knudsen diffusion. These predicted K-p correlations were then used in a finite element model (FEM) to predict the variation of the gas production rate with time (flux-time curves) at the macroscale. The simulation results show that the flux-time curves can be simplified to two linear segments in logarithmic coordinates, which are influenced by the fracture length and initial gas pressure. The predicted results using the PNM-FEM were validated by comparing them with the reported field test data. The method described in this study can be used to upscale the gas transport process from micro- to macroscale, which can provide a predictive tool for the gas production in shales.

Published
2023
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46. Os efeitos da pandemia da COVID-19 na permanência na educação superior. O cenário de uma universidade federal brasileira

Author

Chaiane de Medeiros Rosa, F. F. T. dos Santos, and A. M. Goncalves

Subjects
covid-19, evasão, educação superior, Education (General), General Medicine, permanência estudantil, L7-991
Abstract

espanolEste estudo se propos a pensar os efeitos da pandemia causada pela Covid-19 na per-manencia dos estudantes da educacao superior na Universidade Federal de Goias, no Brasil. Para responder essa questao, foi feita pesquisa documental com base em dados primarios relativos a situacao de vinculo dos estudantes em dois periodos do primeiro semestre letivo de 2020, antes e a partir da pandemia, considerando tanto o panorama geral da universidade, como as particularidades das areas do conhecimento, do ano de ingresso na instituicao e dos graus academicos. Alem disso, para subsidiar a analise dos dados, a pesquisa documental se valeu de documentos oficiais secunda-rios do Ministerio da Educacao e da Universidade Federal de Goias, principalmente, mas tambem do Instituto de Pesquisa Economica Aplicada e da Associacao Nacional dos Dirigentes das Instituicoes Federais de Ensino Superior. Ainda, foi feita pesquisa bibliografica, ancorada em autores que discutem evasao, permanencia estudantil e educacao no contexto da pandemia. Como resultado, o estudo mostrou que houve uma reducao dos vinculos ativos, provocada pelo aumento dos trancamentos e exclusoes, o que se mostrou de forma mais acentuada nas Ciencias Exatas e da Terra e com os ingressantes de 2016 a 2019. EnglishThis study aimed to think about the effects of the pandemic caused by Covid-19 on the higher education students’ stay at the Federal University of Goias (UFG) In order to answer this question, documentary research was carried out based on primary data relating to the students’ bonding situation in two periods of the first academic semester of 2020, before and after the pandemic, considering both the general scene of the university and the particularities of the university, areas of knowledge, year of entry into the institution and academic degrees. In addition, to support the analysis of the data, the documentary research made use of secondary official documents from the Ministry of Education and the UFG, mainly, but also from the Institute of Applied Economic Research and the National Association of the Directors of the Federal Institutions of University Education. Still, bibliographic research was done, anchored in authors who discuss dropout, student permanence and education in the context of the pandemic. As a result, the study showed that there was a reduction in active bonds, caused by the increase in lockouts and exclusions, which was more pronounced in the Exact and Earth Sciences and with the new entrants from 2016 to 2019 portuguesLa propuesta de este estudio es reflexionar sobre los efectos de la pandemia causada por el Covid-19 en la permanencia de los estudiantes de la educacion superior en la Universidade Federal de Goias, en Brasil. Para responder a esa cuestion se hizo una investigacion documental basada en datos primarios relativos a la situacion de vinculo de los estudiantes en dos periodos de primer semestre lectivo del 2020, antes y a partir de la pandemia, considerando tanto el panorama general de la universidad como las particularidades de las areas do conocimiento, del ano de ingreso en la institucion y de los grados academicos. Ademas, para subvencionar el analisis de los datos la investigacion documental recurrio a documentos oficiales secundarios del Ministerio da Educacao y de la Universidade Federal de Goias, principalmente, pero tambien del Instituto de Pesquisa Economica Aplicada y de la Associacao Nacional dos Dirigentes das Instituicoes Federais de Ensino Superior. Ademas, se hizo la investigacion bibliografica basada en autores que discuten evasion, permanencia estudiantil y educacion en el contexto de la pandemia. Como resultado, el estudio mostro que hubo una reduccion de los vinculos activos, provocada por el aumento de las anulaciones y exclusiones, lo que se mostro de forma mas acentuada en Ciencias Exatas e da Terra y con los alumnos de nuevo ingreso del 2016 al 2019

Published
2021

50. Peri-procedural, 30-day and 1 year-outcomes in chronic dialysis patients undergoing transcatheter aortic valve implantation

Author

F Albuquerque, R Lima, R Campante Teles, D Gomes, P Lopes, A Felix Oliveira, M Goncalves, J Brito, L Raposo, S Leal, H Mesquita Gabriel, P De Araujo Goncalves, M De Sousa Almeida, and M Mendes

Subjects
Cardiology and Cardiovascular Medicine
Abstract

Background Patients on chronic dialysis (CD) due to end-stage renal disease (ESRD) with symptomatic severe aortic stenosis eligible for transcatheter aortic valve implantation (TAVI) were excluded from randomized clinical trials. Our study aimed to investigate the outcomes of patients with chronic dialysis who underwent TAVI. Methods Single center analysis on prospectively collected data of all consecutive patients who underwent TAVI between January 2011 and December 2020 according to baseline renal function: chronic dialysis group (CD) and control group (CTRL). Procedural, 30-day and 1-year outcomes were assessed. Outcomes were defined in accordance with the VARC-3 criteria. Results A total of 875 patients underwent TAVI during the study period, of whom 22 (2.5%) were on chronic dialysis. Patients on CD were younger (median age 80 years, [IQR 73–84] vs 84 years, [IQR 80–87]; p Conclusions Chronic dialysis patients submitted to TAVI had significantly higher rates of short-term life threatening and/or major bleeding, short-term and long-term mortality. Careful selection of patients who would benefit from TAVI among patients with ERDS requiring dialysis is necessary to prevent high rates of postprocedural complications and improve outcomes of this high-risk population. Funding Acknowledgement Type of funding sources: None.

Published
2022
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