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Patients with connective tissue diseases and vasculitis often develop refractory skin ulcers in various parts of the body due to abnormal autoimmune reactions, and the skin ulcers caused by different types of diseases have strong heterogeneity. In 2020, The结缔组织疾病及血管炎患者常因异常的自身免疫反应导致全身各部位难愈性皮肤溃疡的发生，不同类型疾病引发的皮肤溃疡具有很强的异质性。2020年《The Journal of Dermatology》杂志发表了日本在2016年版本基础上更新的《结缔组织疾病与血管炎相关皮肤溃疡管理指南》，指导临床更加科学规范地进行相关疾病管理。该文通过对该指南进行解读，以期帮助国内临床医师明确结缔组织疾病与血管炎相关皮肤溃疡的诊断与治疗目标，加速皮肤创面愈合，提高愈合质量。.

CHF3/Ar plasma was used to etch LiTaO3 crystal by inductively coupled plasmas technique. X-ray photoelectron spectroscopy was performed to investigate the etching mechanism. It was found that chemi...