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Technological innovation and the development of new products is what currently boost the competitiveness between enterprises and moves the economy. The technical-scientific advances in Dentistry grow each day and there are great investments by research centers and universities in new materials, especially in dental implantology. The objective was to evaluate the patents deposited and granted in implantology at the National Institute of Industrial Property (INPI) in Brazil. This is a prospective study with searches performed during March 2020 on patents in dental implantology deposited and granted in the INPI. The research was carried out in titles and abstracts of reports on patent applications from the first deposit through to the most current using the search terms "dental implants" and "implantology". The information was extracted from documents and organized into tables and graphs. From 1988, the date of the first deposit, through to 2019 there were 139 patent application deposits. Among the deposited patents, 54% (75) were classified as utility model patents and 25% (35) as invention patents, the others 21% (29) have been in analysis. Brazil holds 80.6% (112) of deposits, and the others are from countries in Latin America, North America, Europe and Africa, and virtually all patents are of type A, which refers to products of human needs. Most deposits of patents for use in implantology in the INPI relate to implant and prosthetic component accessories, indicating greater investment by industry in Brazil in this sector. However, in 30 years there were only 134 deposited patents, suggesting that the importation of products in the area is still great, which consequently makes the products of this area more expensive. Thus, investments in patents play an important role in technological and economic development of a country.

Objective: This research analyzed in vitro the antifungal activity of the solution composed by grapes seed extract Vitis vinifera (Doctor’s A-Z®) against Candida albicans (ATCC 20231) species aiming to determine the minimum inhibitory concentration (MIC) and minimum fungicide concentration (MFC). Methods: To that, were used micro dilution boards of 96 wells where the strain of Candida. Was tested the diluted solutions in distilled water on the concentrations 0.20 g/mL, 0.30 g/mL and 0.40 g/mL. As growing control were used growing fungous, to test the viability of the strains. As positive control, was used nystatin (commercial suspension 100,000 UI/mL) and as sterility control of growing way. The tests were conducted in triplicate and the data obtained were analyzed through the exam Kruskal-Wallis, with significance level of 95% (p

Temporomandibular disorder (TMD) is the term used in Dentistry to define the structural and disorder changes affect the physiology of the masticatory system composed of TMJ and related to musculoskeletal structures. Objective: To conduct a descriptive, transversal and documentary study aiming to determine the profile of 14 TMD patients undergoing simultaneous dental and physiotherapeutic treatment at a private practice of the city of Fortaleza-Ce. Material and methods: The following instruments for the collection of the data were employed: files registering the evaluation and evolution, findings of the radiographic examinations and forms. Data were statistically analyzed through SPSS software, version 10.0. Results: Most of the sample was composed by females aged 32 years (+/-10.60) in average, mainly complaining about chronic headache, masticatory myalgia , TMJ pain, cervicalgy, otalgia, among others. The complete sample presented, at least, one pathology associated to and/or concomitant to TMD. The radiographic findings showed TMJ alterations and tooth losses. Analgesics were the most used drugs. Conclusion: TMD is a complex syndrome, with many etiologies and symptoms, aggravating and perpetuating factors, requiring multiple and even more specialized therapeutic management attempting treatment success.

Purpose: The aim of this study was to identify the variation of caries diagnosis and its relationship with treatment planning, as well as to verify the variation of the diagnosis when using interproximal radiographs or not, through an electronic questionnaire with clinical and radiographic images. Materials and methods: The electronic questionnaire was elaborated with clinical and radiographic images of 10 extracted human molars without defects such as hypoplasias and showing occlusal pits and fisures that could lead to some kind of doubt regarding the presence of caries. Afterwards, histological slides were prepared with sections of the region possibly affected by caries and observed under optical microscopy to validate caries diagnosis. The questionnaire was applied to 159 dentists of both genders, working in primary care in Fortaleza-CE city. The percentage of correct diagnosis for visual examination and visual examination associated with radiography was calculated and the diagnosis provided by the participants and their respective therapeutic options was related. Results: The association of interproximal radiography with visual examination did not influence the detection of enamel caries, however, it contributed significantly to the detection of dentin lesions. Therapeutic indications for the diagnoses provided by participants demonstrated a tendency to overtreating sound teeth and those with enamel caries. Conclusion: The findings of this study raise the need for retraining dental surgeons regarding the caries diagnosis and current therapeutic approaches. Proposição: Objetivou-se, através de um questionário eletrônico com fotos clínicas e radiográficas, identificar a variação de diagnóstico de cárie e sua relação com o planejamento do tratamento além de verificar a variação do diagnóstico quando utilizadas radiografias interproximais ou não. Materiais e métodos: O questionário eletrônico foi elaborado com imagens clínicas e radiográficas de 10 molares humanos extraídos sem defeitos como hipoplasias e apresentando sulcos oclusais que pudessem levar a algum tipo de dúvida em relação à presença de cárie. Em seguida, foram preparadas lâminas histológicas com secções da região possivelmente afetada por cárie e observadas em microscopia óptica para validação do diagnóstico de cárie. O questionário foi aplicado a 159 cirurgiões-dentistas, de ambos os gêneros, atuantes na atenção primária do município de Fortaleza-CE. Foi calculado o percentual de acertos de diagnóstico para exame visual e exame visual associado à radiografia e relacionado o diagnóstico fornecido pelos participantes e às suas respectivas opções terapêuticas. Resultados: A associação da radiografia interproximal ao exame visual não influenciou na detecção de cáries em esmalte, porém, contribuiu significantemente na detecção de lesões em dentina. As indicações terapêuticas para os diagnósticos fornecidos pelos participantes demonstraram tendência ao sobretratamento para dentes hígidos e aqueles com cáries em esmalte. Conclusão: Os achados deste trabalho levantam a necessidade de atualização dos cirurgiões-dentistas quanto ao diagnóstico de cárie e condutas terapêuticas atuais.

The energy density of low power, laser and electromagnetic field , has been used in recent years quite often in the medical field . The study of labeling red blood cells with technetium 99m is used for various evaluations in nuclear medicine including the study of blood volume in neurological intensive care . The aim was to evaluate the in fluence of non - ionizing radiation on the red blood cells labeled in vitro . B lood samples from rats of the Wistar strain divided into two groups were used. The first group used the EDTA and heparin as anticoagulants and received low - power laser induction ( L PL) in the following separately energy density : 3, 6, 9 and 18J/cm². The second group received an electromagnetic field (EMF ) of 60 Hz for 2, 4 , 17 and 21 hours separately . After the induction of the laser and the electromagnetic field , the blood samples w ere labeled with technetium - 99m ( 99mTc). The results indicate that the presence of anticoagulants is able to modify the uptake of technetium - 99m by red blood cells . The laser induced decreases the binding capacity of the technetium - 99m from 3J/cm². From th e foregoing it was found that the radiation is non - ionizing EMF with LBP or alters the binding capacity of 99mTc the erythrocytes and the use of heparin as an anticoagulant gave also a higher labeling efficiency compared with the use of EDTA.The non - ionizi ng radiation has a promising power applications of biomedical sciences can be used for marking targets macromolecules in the body in order to diagnostic procedures and disease control.

For the reconstruction of the anterior teeth that have suffered fractures or restorations involving the incisal angle of the dentistry offers a treatment that offers the ideal copy of the palatal structure, the restoration technique using the wall of silicone. This technique allows to recover the aesthetics of fast, conservatively, and offers a great advantage for dentistry as reducing chair time the child patient. The aim of this study was to report a case where the technique of silicone wall in pediatric patients was applied. Patient MED, female gender, Caucasian race, age 7, showing oblique fracture of the crowns of teeth 11:21. After emergency procedures, the patient had their molded arches and rear molding plaster, wax reconstruction, placement of the wall and restoration of fractured teeth. The case was solved only with resources dentistry, art on the wall, using wax- and light-curing composite resins, reaching a good aesthetic result. Therefore, it is concluded that the technique of making the silicone wall to direct restoration in anterior teeth has advantages in time spent in performing the medical procedure besides satisfying and aesthetic result. Para a reconstrução de dentes anteriores que sofreram fraturas ou restaurações envolvendo o ângulo incisal, a dentística dispõe de um tratamento que oferece a cópia ideal da estrutura palatina, a técnica de restauração usando a muralha de silicona. Esta técnica permite recuperar a estética de forma rápida, conservadora e oferece uma grande vantagem para a Odontopediatria como a redução do tempo de cadeira do paciente infantil. O objetivo do presente trabalho foi relatar um caso onde foi aplicada a técnica da muralha de silicona em paciente pediátrico. Paciente M.E.D, gênero feminino, raça branca, 7 anos de idade, apresentando fratura oblíqua das coroas dos dentes 11 e 21. Após procedimentos emergenciais, a paciente teve suas arcadas moldadas, e posterior moldagem de gesso, reconstrução em cera, confecção da muralha e restauração dos dentes fraturados. O caso foi solucionado apenas com recursos de dentística, técnica da muralha, utilização de ceroplastia e resinas compostas fotopolimerizáveis, alcançando-se um bom resultado estético. Portanto, conclui-se que a confecção da técnica da muralha de silicona para restauração direta em dentes anteriores traz vantagens no tempo gasto para realização do procedimento clínico, além de resultado satisfatório e estético.

Objective: evaluating the epidemiological profile of intensive users of a Psychosocial Care Center. Method: a quantitative descriptive study, of a document basis, in the records of people seen intensively in the period from May to July 2010 in the Psychosocial Assistance Center in Regional Executive Secretary VI in Fortaleza-Ceara. Data were analyzed in IBM SPSS Statistics 20 presented in tables. The research project was approved by the Research Ethics Committee, Opinion nº 10029576-2. Results: there were analyzed 35 medical records of intensive patients, observing that females predominated, with low education and income. Among the complaints of symptoms predominated auditory hallucinations, regarding the diseases predominated mood disorder. Conclusion: the public policies of mental health in Fortaleza should act to meeting the needs of changes in CAPS. Objetivo: avaliar o perfil epidemiológico dos usuários intensivos de um Centro de Atenção Psicossocial. Método: estudo descritivo quantitativo, de base documental, nos prontuários de pessoas atendidas de forma intensiva no período de maio a julho de 2010 no Centro de Assistência Psicossocial da Secretaria Executiva Regional VI do município de Fortaleza-Ceará. Os dados foram analisados no Programa IBM SPSS Statistics 20 apresentados em tabelas. O projeto de pesquisa foi aprovado pelo Comitê de Ética em Pesquisa, Parecer de nº 10029576-2. Resultados: foram analisados 35 prontuários de pacientes intensivos, observou-se que o gênero feminino predominou, principalmente de escolaridade e renda baixas. Entre as queixas de sintomatologia predominaram as alucinações auditivas, quanto às patologias predominou o transtorno de humor. Conclusão: as políticas públicas de saúde mental de Fortaleza devem atuar no sentido de atender as necessidades de mudanças no CAPS. Objetivo: evaluar el perfil epidemiológico de los usuarios intensivos de un Centro de Atención Psicosocial. Método: un estudio descriptivo cuantitativo, de base de documental, en los registros de personas atendidas intensamente en el período mayo-julio, 2010, en el Centro de Asistencia Psicosocial de la Secretaria Ejecutiva Regional VI en Fortaleza-Ceará. Se analizaron los datos en IBM SPSS Statistics 20 presentados en tablas. El proyecto de investigación fue aprobado por el Comité de Ética en la Investigación, Opinión nº 10029576-2. Resultados: eran analizados 35 prontuarios de pacientes intensivos, se observó que las mujeres predominaban, principalmente de baja educación y bajos ingresos. Entre los síntomas de quejas predominan las alucinaciones auditivas, para las enfermedades predominó el trastorno de humor. Conclusión: las políticas públicas de salud mental de Fortaleza deben actuar para satisfacer las necesidades de cambios en el CAPS.

Local anesthetics (LAs) are essential for most invasive procedures. This study aimed to evaluate the various systemic problems due to the indistinct use of LAs. Were used following sources: electronic databases such as PUBMED, MEDLINE, LILACS and BBO, articles in books and periodicals published between the years 2005 to 2012. The descriptors were used: local anesthetics, toxicity, adverse effects and systemic complications. Among the most frequent systemic complications, the effects have been reported in the central nervous system (CNS) and cardiovascular (CVS). Toxic levels of LAs in the CNS is the clinical manifestation of primary generalized tonic-clonic seizures, and result in widespread depression of both systems. CVS-level, the LAs can cause bradycardia and hypotension. Opposing the LAs, sympathomimetic vasoconstictor generate excitatory effects, which intensify in joining the endogenous catecholamines. Can occur even hypersensitivity reactions or hematologic. True anaphylaxis occur mainly in LAs ester type. Furthermore, methylparaben and sodium bisulfite included in the cartridge of LAs are often generated sensitization. The most common hematological abnormality is methemoglobinemia. According to literature, the LAs are safe drugs, but it is necessary expertise in anesthetic technique, dose titration and knowledge about the care needed for their use. Anestésicos locais (ALs) são imprescindíveis a uma gama de procedimentos invasivos. Objetivou-se avaliar os diversos problemas sistêmicos devidos ao uso indistinto de ALs. Foram utilizadas as seguintes fontes: bases de dados eletrônicos tais como PUBMED, MEDLINE, LILACS e BBO, artigos em livros e periódicos, publicados entre os anos de 2005 a 2012. Foram usados os descritores: anestésicos locais, toxicidade, efeitos adversos e complicações sistêmicas. Dentre as complicações sistêmicas mais frequentes, foram relatados os efeitos no Sistema Nervoso Central (SNC) e Cardiovascular (SCV). Em níveis tóxicos de ALs no SNC a manifestação clínica primária é a convulsão tônico-clônica, podendo culminar em depressão generalizada de ambos os sistemas. Em nível de SCV, os ALs podem causar bradicardia e hipotensão arterial. Contrapondo os ALs, os vasoconstritores simpaticomiméticos geram efeitos excitatórios, que se intensificam ao se somar às catecolaminas endógenas. Podem ocorrer ainda reações de hipersensibilidade ou hematológicas. Anafilaxias verdadeiras ocorrem principalmente em ALs do tipo éster. Ademais, o metilparabeno e o bissulfito de sódio, incluídos no tubete de ALs, têm gerado sensibilização frequente. A alteração hematológica mais comum é a metemoglobinemia. Segundo a literatura, os ALs são fármacos seguros, mas é necessária perícia na técnica anestésica, adequação da dose e conhecimento sobre os cuidados necessários à sua utilização. Anestésicos locales (ALs) son esenciales para una amplia gama de procedimientos invasivos. Este estudio tiene como objetivo evaluar los diferentes problemas sistémicos debido al uso de fuerte regalamiento remitido ALs. Se utilizaron las siguientes fuentes: bases de datos electrónicas como PUBMED, MEDLINE, LILACS y BBO, artículos en revistas y libros, publicados entre los años de 2005 a 2012. Los descriptores se emplearon: anestésicos locales, toxicidad, efectos adversos y complicaciones sistémicas. Entre las complicaciones sistémicas más frecuentes, se informó sobre los efectos en el Sistema Nervioso Central (SNC) y cardiovascular (SCV). Los niveles tóxicos de als en el SNC manifestación clínica es la principal crisis convulsivas convulsiones tónico-clónicas generalizadas y pueden culminar en depresión generalizada de ambos sistemas. En el plano de la SCV, el ALS puede causar bradicardia e hipotensión. La contraposición esclerosis lateral amiotrófica, el vasoconstrictor simpaticomiméticos pueden generar efectos excitatorios, intensifican el resumen cuando las catecolaminas endógenas. Pueden producirse reacciones de hipersensibilidad o hematológicas. Pueden sufrir la anafilaxia verdadera ocurre principalmente en la esclerosis lateral amiotrófica tipo éster. Además, metil parabeno y bisulfito de sodio, están incluidos en las copas de la esclerosis lateral amiotrófica, ha generado conciencia frecuentes. La enmienda es el más común que afecta la metahemoglobinemia. De acuerdo con la literatura, la LAs son fármacos seguros, pero es necesaria la experiencia en la técnica anestésica, ajuste de la dosis y el conocimiento sobre los cuidados necesarios para su uso.