27 results on '"Locke, Gregory"'
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2. Identification and characterization of TYK2 pseudokinase domain stabilizers that allosterically inhibit TYK2 signaling
3. Discovery and structure activity relationships of 7-benzyl triazolopyridines as stable, selective, and reversible inhibitors of myeloperoxidase
4. DGKα/ζ inhibitors combine with PD-1 checkpoint therapy to promote T cell–mediated antitumor immunity.
5. Chapter Twenty-Three - Identification and characterization of TYK2 pseudokinase domain stabilizers that allosterically inhibit TYK2 signaling
6. Discovery of Non-Nucleotide Small-Molecule STING AgonistsviaChemotype Hybridization
7. Small molecule and macrocyclic pyrazole derived inhibitors of myeloperoxidase (MPO)
8. Differential activation of recombinant human acetyl-CoA carboxylases 1 and 2 by citrate
9. Discovery of Orally Active Isofuranones as Potent, Selective Inhibitors of Hematopoetic Progenitor Kinase 1
10. Enhanced antitumor immunity by a novel small molecule HPK1 inhibitor
11. Benzothiazole-based compounds as potent endothelial lipase inhibitors
12. Identification of substituted benzothiazole sulfones as potent and selective inhibitors of endothelial lipase
13. Identification of Reversible Small Molecule Inhibitors of Endothelial Lipase (EL) That Demonstrate HDL-C Increase In Vivo
14. Role of Lys 100 in human dihydroorotate dehydrogenase: mutagenesis studies and chemiccal rescue by external amines
15. Discovery of Non-Nucleotide Small-Molecule STING Agonists via Chemotype Hybridization.
16. Corrigendum to “Identification of substituted benzothiazole sulfones as potent and selective inhibitors of endothelial lipase” [Bioorg. Med. Chem. Lett. 29 (2019) 1918–1921]
17. Discovery of Non-Nucleotide Small-Molecule STING Agonists viaChemotype Hybridization
18. Enoyl-ACP Reductase (FabI) of Haemophilus influenzae: Steady-State Kinetic Mechanism and Inhibition by Triclosan and Hexachlorophene
19. A Second Dihydroorotate Dehydrogenase (Type A) of the Human Pathogen Enterococcus faecalis: Expression, Purification, and Steady-State Kinetic Mechanism
20. Sulfonylated Benzothiazoles as Inhibitors of Endothelial Lipase
21. Potent Triazolopyridine Myeloperoxidase Inhibitors
22. Triazolopyrimidines identified as reversible myeloperoxidase inhibitors
23. Potency, selectivity and prolonged binding of saxagliptin to DPP4: maintenance of DPP4 inhibition by saxagliptin in vitro and ex vivo when compared to a rapidly-dissociating DPP4 inhibitor
24. Expression, purification, and characterization of human and rat acetyl cfenzyme A carboxylase (ACC) isozymes
25. Role of Lys100 in Human Dihydroorotate Dehydrogenase: Mutagenesis Studies and Chemical Rescue by External Amines
26. Role of Lys100 in Human Dihydroorotate Dehydrogenase: Mutagenesis Studies and Chemical Rescue by...
27. Identification and characterization of TYK2 pseudokinase domain stabilizers that allosterically inhibit TYK2 signaling.
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