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AbstractA pair of atropisomers secofumitremorgins C (1a) and D (1b), together with fifteen known alkaloids (2-16), were isolated from a saltern-derived fungus Aspergillus fumigatus GXIMD00544. The structures of atropisomers 1a and 1b were elucidated by the detailed spectroscopic data, chemical reaction and quantum chemical calculations. Compounds 1 and 8 displayed antifungal spore germination effects against plant pathogenic fungus associated with sugarcane Fusarium sp. with inhibitory rates of 53% and 77% at the concentration of 100 µM, repectively. Atropisomers 1 also exhibited antifouling potential against Balanus amphitrite larval settlement with an inhibitory rate of 96% at the concentration of 100 µM. [ABSTRACT FROM AUTHOR]

Objective: Effects of analgesia effect of ambulatory labor analgesia and its influence on the mother and fetus. Methods: A retrospective analysis of 177 cases of pregnant women in our hospital from September 2012 to September 2013. According to the mode of delivery, the cases were divided into painless delivery group (n=83) and conventional delivery group (n=94), and compared the two groups in the labor pain score, birth process and newborn situation. Results: Cesarean section rate was significantly lower in painless childbirth group than that in conventional delivery group; the first stage in painless childbirth group is shorter than the conventional delivery group,the second stage of labor was significantly prolonged compared with that in the conventional delivery group (P<0.05), third stage has no significant statistical difference in two groups (P>0.05); painless childbirth pregnant woman the production process of VAS scores were significantly lower than that of conventional delivery group (P<0.05); and the incidence of neonatal Apgar score of two groups of fetal distress were no significant statistical difference (P>0.05); the two group of postpartum hemorrhage and the incidence of bleeding volume were not significantly difference (P>0.05); conventional delivery group no untoward reaction of postpartum, painless labor group 4 cases of orthostatic hypotension (5.6%), 3 cases of lower extremity muscle weakness (4.2%), were after symptomatic treatment in 3 h mitigation. Conclusions: Ambulatory labor analgesia can significantly reduce maternal pain of the production process, and will not lead to severe postpartum complications, fetal harm, is an effective, safe childbirth analgesia method, is worthy of clinical application. [ABSTRACT FROM AUTHOR]