84 results on '"Lauerer, P"'
Search Results
2. Referring physicians' intention to use hospital report cards for hospital referral purposes in the presence or absence of patient-reported outcomes: a randomized trial
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Emmert, Martin, Schindler, Anja, Heppe, Laura, Sander, Uwe, Patzelt, Christiane, Lauerer, Michael, Nagel, Eckhard, Frömke, Cornelia, Schöffski, Oliver, and Drach, Cordula
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- 2024
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3. The elicitation of patient and physician preferences for calculating consumer-based composite measures on hospital report cards: results of two discrete choice experiments
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Emmert, Martin, Rohrbacher, Stefan, Meier, Florian, Heppe, Laura, Drach, Cordula, Schindler, Anja, Sander, Uwe, Patzelt, Christiane, Frömke, Cornelia, Schöffski, Oliver, and Lauerer, Michael
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- 2023
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4. Prekarierinnen? Geschlechterspezifische Unterschiede prekärer Arbeit im Journalismus
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Jana Rick and Corinna Lauerer
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Communication. Mass media ,P87-96 - Abstract
Vor dem Hintergrund finanzieller Herausforderungen der Medienbranche in den vergangenen Jahrzehnten wird seit Jahren über die Prekarisierung der Arbeitsbedingungen im Journalismus diskutiert, die zur Erosion der Nachrichtenqualität führen kann. Diese Studie untersuchte den vernachlässigten geschlechterspezifischen Aspekt prekärer Beschäftigung im Journalismus allgemein und im Krisenkontext. In einer Onlinebefragung von 983 hauptberuflich tätigen Journalist*innen wurde eruiert, ob Journalistinnen in Deutschland stärker von objektiver Prekarität betroffen sind als Journalisten. Die Ergebnisse sprechen sowohl für geschlechterspezifische als auch geschlechterunabhängige Prekarität. Unabhängig vom Geschlecht weisen Freiberufler*innen das größte Prekaritätspotenzial auf. Als geschlechtsspezifischer Prekaritätsindikator erweist sich neben einem Gender-Pay-Gap der Umstand, dass sich Journalistinnen vor allem aufgrund von Care-Arbeit häufiger in atypischer Beschäftigung befinden. Die Ergebnisse sprechen für hartnäckige geschlechterspezifische Ungleichheit im Journalismus, die das Prekaritätspotenzial von Frauen erhöht. Die Covid-19-Pandemie verschärfte unsichere Arbeitssituationen vieler Journalist*innen akut, betraf aber nicht Journalistinnen im Speziellen.
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- 2024
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5. Dispersal and persistence of cup plant seeds (Silphium perfoliatum): do they contribute to potential invasiveness?
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L. Marie Ende, Lukas Hummel, and Marianne Lauerer
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Plant ecology ,QK900-989 - Abstract
Background and aims – The cup plant (Silphium perfoliatum) is being grown in Germany as a promising new bioenergy crop with an increasing area under cultivation in the last years. Its alien status, its high productivity, and high reproductive potential could carry the risk of this species becoming invasive. The present study investigates the dispersal and persistence of cup plant seeds, to contribute to the assessment of its invasive potential. Material and methods – For this purpose, four experimental studies were conducted in Germany, Central Europe: wind dispersal distance was measured in a field experiment for wind speeds up to 7 m.s-1. The seeds were offered to rodents in different habitats near to a cup plant field. We observed seed persistence and germination over 4 weeks storing in water and over 4 years storing in different soil depths. Key results – Cup plant seeds are dispersed by wind only over a few meters. In the forest, rodents removed 100% of the offered seeds, in open habitats none. Independent of the duration of storage in water, germination rate of the cup plant seeds was constantly high. Most of the seeds already germinated in water in the first two weeks. Stored on the soil surface and at 10 cm soil depth, the seeds germinated already in the first two years. Stored at 30 cm depth, one third of the seeds retained their germination ability over four years. Conclusion – Wind serves as short-distance dispersal vector for cup plant seeds. Rodents remove the seeds, but it is unknown whether they disperse them or just eat them. Water could disperse the seeds, which retain their germination ability, over long distances. The cup plant could therefore spread and possibly become invasive in Central Europe, and therefore measures are suggested to prevent its dispersal and spontaneous settlement.
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- 2024
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6. CaMKIIδ-dependent dysregulation of atrial Na+ homeostasis promotes pro-arrhythmic activity in an obstructive sleep apnea mouse model
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Philipp Hegner, Florian Ofner, Benedikt Schaner, Mathias Gugg, Maximilian Trum, Anna-Maria Lauerer, Lars Siegfried Maier, Michael Arzt, Simon Lebek, and Stefan Wagner
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sleep-disordered breathing ,reactive oxygen species ,CaMKIIδ ,Na+ homeostasis ,cardiac arrhythmias ,obstructive sleep apnea ,Therapeutics. Pharmacology ,RM1-950 - Abstract
BackgroundObstructive sleep apnea (OSA) has been linked to various pathologies, including arrhythmias such as atrial fibrillation. Specific treatment options for OSA are mainly limited to symptomatic approaches. We previously showed that increased production of reactive oxygen species (ROS) stimulates late sodium current through the voltage-dependent Na+ channels via Ca2+/calmodulin-dependent protein kinase IIδ (CaMKIIδ), thereby increasing the propensity for arrhythmias. However, the impact on atrial intracellular Na+ homeostasis has never been demonstrated. Moreover, the patients often exhibit a broad range of comorbidities, making it difficult to ascertain the effects of OSA alone.ObjectiveWe analyzed the effects of OSA on ROS production, cytosolic Na+ level, and rate of spontaneous arrhythmia in atrial cardiomyocytes isolated from an OSA mouse model free from comorbidities.MethodsOSA was induced in C57BL/6 wild-type and CaMKIIδ-knockout mice by polytetrafluorethylene (PTFE) injection into the tongue. After 8 weeks, their atrial cardiomyocytes were analyzed for cytosolic and mitochondrial ROS production via laser-scanning confocal microscopy. Quantifications of the cytosolic Na+ concentration and arrhythmia were performed by epifluorescence microscopy.ResultsPTFE treatment resulted in increased cytosolic and mitochondrial ROS production. Importantly, the cytosolic Na+ concentration was dramatically increased at various stimulation frequencies in the PTFE-treated mice, while the CaMKIIδ-knockout mice were protected. Accordingly, the rate of spontaneous Ca2+ release events increased in the wild-type PTFE mice while being impeded in the CaMKIIδ-knockout mice.ConclusionAtrial Na+ concentration and propensity for spontaneous Ca2+ release events were higher in an OSA mouse model in a CaMKIIδ-dependent manner, which could have therapeutic implications.
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- 2024
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7. Preferences of People Living with HIV for Long-Acting Antiretroviral Treatment in Germany: Evidence from a Discrete Choice Experiment
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Emmert, Martin, Rohrbacher, Stefan, Jahn, Jennifer, Fernando, Katharina, and Lauerer, Michael
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- 2023
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8. Digital health applications in the self‐management of epilepsy—A survey on patients' perspective
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Salima Houta, Alisa Bader, Jana‐Sophie Effert, Birgitta Esser, Jasmin Henze, Alexandra Spaic, Feline Zocher, Michael Lauerer, and Rainer Surges
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digital health literacy ,health information exchange ,knowledge about digital health infrastructures ,mobile applications ,self‐management ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Abstract Objective Digital health applications can be prescribed since 2019 in Germany, which is likely to facilitate a broad use of epilepsy self‐management applications, possibly directly connected to clinical systems via telematics infrastructures. This article reports on patients' interest in digital support for epilepsy self‐management, influencing factors and patients' knowledge about digitization of health care in Germany. Methods This work is based on self‐reported data from 115 people with epilepsy participating in an anonymous online survey with a total of 54 questions covering several topics, including sociodemographics and epilepsy manifestation, use of technology in general and for treatment support, training programs, affinity for technology, knowledge on the digital infrastructure in Germany, and self‐efficacy in dealing with chronic illness. The self‐constructed questionnaire uses existing instruments like TA‐EG, SES6G, and Hoffmeyer‐Zlotnik sociodemographic questionnaire. To analyze the knowledge about digitalization in health care, a combination of self‐assessment and knowledge quiz was used. The analysis was performed using descriptive methods and inferential statistics (t‐test, reliability analysis, and correlations). Results Participants were most interested in seizure alerting and documentation with the possibility to share documentation with physicians. The analysis of technology affinity showed medium enthusiasm, with positively perceived consequences being rated higher than the negatively perceived consequences of technology use. Knowledge on national health infrastructures was mediocre and training on this was judged to be essential and desired. Furthermore, a significant correlation was found between interest in use and affinity for technology (enthusiasm for technology [r = 0.29; P = 0.00]) and positively perceived consequences of technology (r = 0.33; P = 0.00). Significance Our results underline the high relevance of digital solutions for patients and the importance of individual training opportunities in digital health literacy, thereby enabling patients to decide competently for or against offered digital solutions.
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- 2023
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9. Percentage brain volume change in multiple sclerosis mainly reflects white matter and cortical volume
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Markus Lauerer, Matthias Bussas, Viola Pongratz, Achim Berthele, Jan S Kirschke, Benedikt Wiestler, Claus Zimmer, Bernhard Hemmer, and Mark Mühlau
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Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Abstract Brain atrophy in multiple sclerosis (MS), as measured by percentage brain volume change (PBVC) from brain magnetic resonance imaging (MRI), has been established as an outcome parameter in clinical trials. It is unknown to what extent volume changes within different brain tissue compartments contribute to PBVC. We analyzed pairs of MRI scans (at least 6 months apart) in 600 patients with relapsing–remitting MS. Multiple regression revealed that PBVC mainly reflects volume loss of white and cortical gray matter, while deep gray matter and white matter lesions were less represented. Our findings aid the interpretation of PBVC changes in MS.
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- 2023
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10. Spreading of the cup plant (Silphium perfoliatum) in northern Bavaria (Germany) from bioenergy crops
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L. Marie Ende and Marianne Lauerer
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Biology (General) ,QH301-705.5 - Abstract
Invasive species can be the cause of severe problems for biodiversity, economy and human health. The cup plant (Silphium perfoliatum) is native to eastern North America and is increasingly cultivated in Germany as a new bioenergy crop. Its growth characteristics and autecology do not exclude a possible invasive potential. However, there are hardly any studies on this to date. In this study, habitat requirements for spontaneous colonization and establishment of the cup plant were investigated. Therefore, a 15 m radius around eleven cup plant fields in northern Bavaria (Germany) was examined. Data on cup plant colonization, habitat type, vegetation structure, ground cover, and further site conditions using the Ellenberg indicator values were collected and analyzed by logistic regression models. Spontaneously colonized cup plants were found in a wide range of habitats. Open habitats and human settlement areas were particularly suitable, especially field margins and agricultural paths. A portion of open soil of about 25% was preferentially colonized. Cup plants occurred predominantly within the first few meters of the field margin and increasingly around cup plant fields that have existed for a longer period. Favorable for the development of stems and thus for flowering, fruiting and establishing are warmer sites with a high herb layer. Individual plants that had developed a stem persist for several years and increased their stem number over time. The number of stem-developing individuals also increased over time. Thus, there exist an enormous potential for spread in the future. However, an invasive potential could not be confirmed based on the present study, because a threat of biodiversity was not proven.
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- 2022
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11. Thermo-physical Properties of FeNi36 and Possibilities for Determination of the Curie Point
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Lauerer, Alexander and Post, Ekkehard
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- 2023
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12. NMR close to Mega-Bar Pressures
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Meier, Thomas, Khandarkhaeva, Saiana, Petitgirard, Sylvain, Körber, Thomas, Lauerer, Alexander, Rössler, Ernst, and Dubrovinsky, Leonid
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Physics - Applied Physics - Abstract
The past 15 years have seen an astonishing increase in Nuclear Magnetic Resonance (NMR) sensitivity and accessible pressure range in high-pressure NMR experiments, owing to a series of new developments of NMR spectroscopy applied to the diamond anvil cell (DAC). Recently, with the application of electro-magnetic lenses, so-called Lenz lenses, in toroidal diamond indenter cells, pressures of up to 72 GPa with NMR spin sensitivities of about 10^12 spins/(Hz^1/2) has been achieved. Here, we describe the implementation of a refined NMR resonator structure using a pair of double stage Lenz lenses driven by a Helmholtz coil within a standard DAC, allowing to measure sample volumes as small as 100 pl prior to compression. With this set-up, pressures close to the mega-bar regime (1 Mbar = 100 GPa) could be realised repeatedly, with enhanced spin sensitivities of about 5x10^11 spin/(Hz^1/2). The manufacturing and handling of these new NMR-DACs is relatively easy and straightforward, which will allow for further applications in physics, chemistry, or biochemistry.
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- 2018
13. De Novo Pathogenic Variants in CACNA1E Cause Developmental and Epileptic Encephalopathy with Contractures, Macrocephaly, and Dyskinesias
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Helbig, Katherine L, Lauerer, Robert J, Bahr, Jacqueline C, Souza, Ivana A, Myers, Candace T, Uysal, Betül, Schwarz, Niklas, Gandini, Maria A, Huang, Sun, Keren, Boris, Mignot, Cyril, Afenjar, Alexandra, de Villemeur, Thierry Billette, Héron, Delphine, Nava, Caroline, Valence, Stéphanie, Buratti, Julien, Fagerberg, Christina R, Soerensen, Kristina P, Kibaek, Maria, Kamsteeg, Erik-Jan, Koolen, David A, Gunning, Boudewijn, Schelhaas, H Jurgen, Kruer, Michael C, Fox, Jordana, Bakhtiari, Somayeh, Jarrar, Randa, Padilla-Lopez, Sergio, Lindstrom, Kristin, Jin, Sheng Chih, Zeng, Xue, Bilguvar, Kaya, Papavasileiou, Antigone, Xing, Qinghe, Zhu, Changlian, Boysen, Katja, Vairo, Filippo, Lanpher, Brendan C, Klee, Eric W, Tillema, Jan-Mendelt, Payne, Eric T, Cousin, Margot A, Kruisselbrink, Teresa M, Wick, Myra J, Baker, Joshua, Haan, Eric, Smith, Nicholas, Sadeghpour, Azita, Davis, Erica E, Katsanis, Nicholas, Genomics, Task Force for Neonatal, Allori, Alexander, Angrist, Misha, Ashley, Patricia, Bidegain, Margarita, Boyd, Brita, Chambers, Eileen, Cope, Heidi, Cotten, C Michael, Curington, Theresa, Ellestad, Sarah, Fisher, Kimberley, French, Amanda, Gallentine, William, Goldberg, Ronald, Hill, Kevin, Kansagra, Sujay, Katsanis, Sara, Kurtzberg, Joanne, Marcus, Jeffrey, McDonald, Marie, Mikati, Mohammed, Miller, Stephen, Murtha, Amy, Perilla, Yezmin, Pizoli, Carolyn, Purves, Todd, Ross, Sherry, Smith, Edward, Wiener, John, Corbett, Mark A, MacLennan, Alastair H, Gecz, Jozef, Biskup, Saskia, Goldmann, Eva, Rodan, Lance H, Kichula, Elizabeth, Segal, Eric, Jackson, Kelly E, Asamoah, Alexander, Dimmock, David, McCarrier, Julie, Botto, Lorenzo D, Filloux, Francis, Tvrdik, Tatiana, and Cascino, Gregory D
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Medical Physiology ,Biomedical and Clinical Sciences ,Neurodegenerative ,Brain Disorders ,Neurosciences ,Epilepsy ,Pediatric ,2.1 Biological and endogenous factors ,Aetiology ,Neurological ,Adolescent ,Adult ,Calcium Channels ,R-Type ,Cation Transport Proteins ,Child ,Child ,Preschool ,Contracture ,Dyskinesias ,Female ,Genetic Variation ,Humans ,Infant ,Male ,Megalencephaly ,Neurodevelopmental Disorders ,Spasms ,Infantile ,Task Force for Neonatal Genomics ,Deciphering Developmental Disorders Study ,CACNA1E ,ion channel ,arthrogryposis ,calcium channel ,epilepsy ,Biological Sciences ,Medical and Health Sciences ,Genetics & Heredity ,Biological sciences ,Biomedical and clinical sciences ,Health sciences - Abstract
Developmental and epileptic encephalopathies (DEEs) are severe neurodevelopmental disorders often beginning in infancy or early childhood that are characterized by intractable seizures, abundant epileptiform activity on EEG, and developmental impairment or regression. CACNA1E is highly expressed in the central nervous system and encodes the α1-subunit of the voltage-gated CaV2.3 channel, which conducts high voltage-activated R-type calcium currents that initiate synaptic transmission. Using next-generation sequencing techniques, we identified de novo CACNA1E variants in 30 individuals with DEE, characterized by refractory infantile-onset seizures, severe hypotonia, and profound developmental impairment, often with congenital contractures, macrocephaly, hyperkinetic movement disorders, and early death. Most of the 14, partially recurring, variants cluster within the cytoplasmic ends of all four S6 segments, which form the presumed CaV2.3 channel activation gate. Functional analysis of several S6 variants revealed consistent gain-of-function effects comprising facilitated voltage-dependent activation and slowed inactivation. Another variant located in the domain II S4-S5 linker results in facilitated activation and increased current density. Five participants achieved seizure freedom on the anti-epileptic drug topiramate, which blocks R-type calcium channels. We establish pathogenic variants in CACNA1E as a cause of DEEs and suggest facilitated R-type calcium currents as a disease mechanism for human epilepsy and developmental disorders.
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- 2018
14. Competitiveness of the Exotic Silphium perfoliatum against the Native Urtica dioica: A Field Experiment
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L. Marie Ende, Sophie-Juliane Schwarzer, Alexandra Ebner, and Marianne Lauerer
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Ecology ,QH540-549.5 ,General. Including nature conservation, geographical distribution ,QH1-199.5 - Abstract
Silphium perfoliatum (cup plant) is native to North America and is increasingly used as a bioenergy crop in Germany. Spontaneous occurrences of this species have already been detected in several European countries. To assess the possible risk to biodiversity by spreading of S. perfoliatum, we investigated the competitiveness of this species against the native and highly competitive Urtica dioica over four years in a field experiment in Bayreuth (Germany). S. perfoliatum grew well among U. dioica, although its biomass was strongly reduced by surrounding U. dioica. Projection area, plant height, and reproductive potential were less or similarly reduced by surrounding U. dioica as by the intraspecific competition. Moreover, S. perfoliatum significantly suppressed the growth of the competitive U. dioica. A settlement and establishment of S. perfoliatum in the native flora of Central Europe and a suppression of uncompetitive plant species are therefore conceivable.
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- 2023
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15. Chirurgie im Spannungsfeld „Humanität-Ethik-Ökonomie“
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Nagel, E., Lauerer, M., and Henzler, D.
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- 2022
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16. Unerfüllte Behandlungswünsche jüngerer und älterer Menschen in sozial deprivierten Räumen: eine qualitative Interviewstudie im Ruhrgebiet.
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Heidenreiter, Sarah, Lauerer, Michael, and Nagel, Eckhard
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- 2024
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17. Comparing myelin-sensitive magnetic resonance imaging measures and resulting g-ratios in healthy and multiple sclerosis brains
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Ronja C. Berg, Aurore Menegaux, Thomas Amthor, Guillaume Gilbert, Maria Mora, Sarah Schlaeger, Viola Pongratz, Markus Lauerer, Christian Sorg, Mariya Doneva, Irene Vavasour, Mark Mühlau, and Christine Preibisch
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Myelin imaging ,G-ratio mapping ,Myelin and axonal volume fractions ,Multiple sclerosis ,White matter lesions ,Magnetic resonance imaging ,Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 - Abstract
The myelin concentration and the degree of myelination of nerve fibers can provide valuable information on the integrity of human brain tissue. Magnetic resonance imaging (MRI) of myelin-sensitive parameters can help to non-invasively evaluate demyelinating diseases such as multiple sclerosis (MS). Several different myelin-sensitive MRI methods have been proposed to determine measures of the degree of myelination, in particular the g-ratio. However, variability in underlying physical principles and different biological models influence measured myelin concentrations, and consequently g-ratio values. We therefore investigated similarities and differences between five different myelin-sensitive MRI measures and their effects on g-ratio mapping in the brains of both MS patients and healthy volunteers.We compared two different estimates of the myelin water fraction (MWF) as well as the inhomogeneous magnetization transfer ratio (ihMTR), magnetization transfer saturation (MTsat), and macromolecular tissue volume (MTV) in 13 patients with MS and 14 healthy controls. In combination with diffusion-weighted imaging, we derived g-ratio parameter maps for each of the five different myelin measures.The g-ratio values calculated from different myelin measures varied strongly, especially in MS lesions. While, compared to normal-appearing white matter, MTsat and one estimate of the MWF resulted in higher g-ratio values within lesions, ihMTR, MTV, and the second MWF estimate resulted in lower lesion g-ratio values.As myelin-sensitive measures provide rough estimates of myelin content rather than absolute myelin concentrations, resulting g-ratio values strongly depend on the utilized myelin measure and model used for g-ratio mapping. When comparing g-ratio values, it is, thus, important to utilize the same MRI methods and models or to consider methodological differences. Particular caution is necessary in pathological tissue such as MS lesions.
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- 2022
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18. Invasive Impatiens glandulifera: A driver of changes in native vegetation?
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Judith Bieberich, Stefanie Müller, Heike Feldhaar, and Marianne Lauerer
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causality of impact ,context‐dependency ,plant invasion ,planting experiment ,removal experiment ,riverside vegetation ,Ecology ,QH540-549.5 - Abstract
Abstract Biological invasions are one of the major threats to biodiversity worldwide and contribute to changing community patterns and ecosystem processes. However, it is often not obvious whether an invader is the “driver” causing ecosystem changes or a “passenger” which is facilitated by previous ecosystem changes. Causality of the impact can be demonstrated by experimental removal of the invader or introduction into a native community. Using such an experimental approach, we tested whether the impact of the invasive plant Impatiens glandulifera on native vegetation is causal, and whether the impact is habitat‐dependent. We conducted a field study comparing invaded and uninvaded plots with plots from which I. glandulifera was removed and plots where I. glandulifera was planted within two riparian habitats, alder forests and meadows. A negative impact of planting I. glandulifera and a concurrent positive effect of removal on the native vegetation indicated a causal effect of I. glandulifera on total native biomass and growth of Urtica dioica. Species α‐diversity and composition were not affected by I. glandulifera manipulations. Thus, I. glandulifera had a causal but low effect on the native vegetation. The impact depended slightly on habitat as only the effect of I. glandulifera planting on total biomass was slightly stronger in alder forests than meadows. We suggest that I. glandulifera is a “back‐seat driver” of changes, which is facilitated by previous ecosystem changes but is also a driver of further changes. Small restrictions of growth of the planted I. glandulifera and general association of I. glandulifera with disturbances indicate characteristics of a back‐seat driver. For management of I. glandulifera populations, this requires habitat restoration along with removal of the invader.
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- 2021
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19. Transport in Nanoporous Materials Including MOFs: The Applicability of Fick’s Laws
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Titze, Tobias, Lauerer, Alexander, Heinke, Lars, Chmelik, Christian, Zimmermann, Nils ER, Keil, Frerich J, Ruthven, Douglas M, and Kärger, Jörg
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Biological Transport ,Magnetic Resonance Spectroscopy ,Microscopy ,Models ,Chemical ,Nanostructures ,Porosity ,diffusion ,Fick's laws ,metal-organic frameworks ,nanoporous materials ,zeolites ,Fick’s laws ,Chemical Sciences ,Organic Chemistry - Abstract
Diffusion in nanoporous host-guest systems is often considered to be too complicated to comply with such "simple" relationships as Fick's first and second law of diffusion. However, it is shown herein that the microscopic techniques of diffusion measurement, notably the pulsed field gradient (PFG) technique of NMR spectroscopy and microimaging by interference microscopy (IFM) and IR microscopy (IRM), provide direct experimental evidence of the applicability of Fick's laws to such systems. This remains true in many situations, even when the detailed mechanism is complex. The limitations of the diffusion model are also discussed with reference to the extensive literature on this subject.
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- 2015
20. Micro-habitat and season dependent impact of the invasive Impatiens glandulifera on native vegetation
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Judith Bieberich, Heike Feldhaar, and Marianne Lauerer
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Biology (General) ,QH301-705.5 - Abstract
The impact of invasive species is often difficult to assess due to species × ecosystem interactions. Impatiens glandulifera heavily invaded several habitat types in Central Europe but its impact on native plant communities is rated ambiguously. One reason could be that the impact differs between habitat types or even between environmentally heterogeneous patches (micro-habitats) within one habitat type. In the present study a vegetation survey was performed within heterogeneous riverside habitats in Germany investigating the impact of I. glandulifera on native vegetation in dependence of environmental conditions. The vegetation was recorded in summer and spring because of seasonal species turnover and thus potentially different impact of the invasive plant. We found that the cover of I. glandulifera depended on environmental conditions resulting in a patchy occurrence. I. glandulifera did not have any impact on plant alpha-diversity but reduced the cover of the native vegetation, especially of the dominant species. This effect depended on micro-habitat and season. The native vegetation was most affected in bright micro-habitats, especially those with a high soil moisture. Not distinguishing between micro-habitats, plant species composition was not affected in summer but in spring. However, environmental conditions had a higher impact on the native vegetation than I. glandulifera. We conclude that within riparian habitats the threat of I. glandulifera to the native vegetation can be rated low since native species were reduced in cover but not excluded from the communities. This might be due to patchy occurrence and year-to-year changes in cover of I. glandulifera. The context-dependency in terms of micro-habitat and season requires specific risk assessments which is also an opportunity for nature conservation to develop management plans specific to the different habitats. Particular attention should be given to habitats that are bright and very wet since the effect of I. glandulifera was strongest in these habitats.
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- 2020
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21. Rapid Diagnosis of Central Nervous System Scedosporiosis by Specific Quantitative Polymerase Chain Reaction Applied to Formalin-Fixed, Paraffin-Embedded Tissue
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Robert J. Lauerer, Emely Rosenow, Rudi Beschorner, Johann-Martin Hempel, Georgios Naros, Anna Hofmann, Katharina Berger, Jennifer Sartor-Pfeiffer, Annerose Mengel, Ulf Ziemann, Volker Rickerts, and Katharina Feil
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Scedosporium apiospermum ,brain abscess ,specific qPCR ,Biology (General) ,QH301-705.5 - Abstract
Scedosporium (S.) apiospermum is a typical mold causing cerebral abscesses, often after near-drowning. Infections are associated with high morbidity and mortality due to diagnostic challenges including the need for prolonged incubation of cultures. In addition, histopathological differentiation from other filamentous fungi, including Aspergillus fumigatus, may not be possible, excluding early specific diagnosis and targeted therapy. Polymerase chain reaction (PCR) on tissue samples can rapidly identify fungi, leading to an earlier adequate treatment. Due to an extensive spectrum of causative fungi, broad-range PCRs with amplicon sequencing have been endorsed as the best DNA amplification strategy. We herein describe a case with brain abscesses due to S. apiospermum in a 66-year-old immunocompromised female patient. While broad-range PCR failed to identify a fungal pathogen from a cerebral biopsy demonstrating hyaline mold hyphae, specific quantitative PCR (qPCR) identified Scedosporium and ruled out Aspergillus, the most prevalent agent of central nervous system mold infection. A panel of specific qPCR assays, guided by the morphology of fungal elements in tissue or as a multiplex assay, may be a successful molecular approach to identify fungal agents of brain abscesses. This also applies in the presence of negative broad-range fungal PCR, therefore providing diagnostic and therapeutic potential for early specific management and improvement of patient clinical outcome.
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- 2021
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22. Prognostic value of spinal cord lesion measures in early relapsing-remitting multiple sclerosis
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Lauerer, Markus, McGinnis, Julian, Bussas, Matthias, El Husseini, Malek, Pongratz, Viola, Engl, Christina, Wuschek, Alexander, Berthele, Achim, Riederer, Isabelle, Kirschke, Jan S, Zimmer, Claus, Hemmer, Bernhard, and Mu¨hlau, Mark
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BackgroundSpinal cord (SC) lesions have been associated with unfavourable clinical outcomes in multiple sclerosis (MS). However, the relation of whole SC lesion number (SCLN) and volume (SCLV) to the future occurrence and type of confirmed disability accumulation (CDA) remains largely unexplored.MethodsIn this monocentric retrospective study, SC lesions were manually delineated. Inclusion criteria were: age between 18 and 60 years, relapsing-remitting MS, disease duration under 2 years and clinical follow-up of 5 years. The first CDA event after baseline, determined by a sustained increase in the Expanded Disability Status Scale over 6 months, was classified as either progression independent of relapse activity (PIRA) or relapse-associated worsening (RAW). SCLN and SCLV were compared between different (sub)groups to assess their prospective value.Results204 patients were included, 148 of which had at least one SC lesion and 59 experienced CDA. Patients without any SC lesions experienced significantly less CDA (OR 5.8, 95% CI 2.1 to 19.8). SCLN and SCLV were closely correlated (rs=0.91, p<0.001) and were both significantly associated with CDA on follow-up (p<0.001). Subgroup analyses confirmed this association for patients with PIRA on CDA (34 events, p<0.001 for both SC lesion measures) but not for RAW (25 events, p=0.077 and p=0.22).ConclusionPatients without any SC lesions are notably less likely to experience CDA. Both the number and volume of SC lesions on MRI are associated with future accumulation of disability largely independent of relapses.
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- 2024
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23. Die Widerspruchslösung – Erfolgs- oder Störfaktor für die Gewebespende? Eine qualitative Studie auf Basis multidisziplinärer Expert*inneninterviews.
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Kirchner, Katja, Lauerer, Michael, and Nagel, Eckhard
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- 2023
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24. Diagnosing ARVC in Pediatric Patients Applying the Revised Task Force Criteria: Importance of Imaging, 12-Lead ECG, and Genetics
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Steinmetz, Michael, Krause, Ulrich, Lauerer, Peter, Konietschke, Frank, Aguayo, Randolph, Ritter, Christian Oliver, Schuster, Andreas, Lotz, Joachim, Paul, Thomas, and Staab, Wieland
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- 2018
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25. Journalismus in Deutschland: Aktuelle Befunde zu Kontinuität und Wandel im deutschen Journalismus
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Steindl, Nina, Lauerer, Corinna, and Hanitzsch, Thomas
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- 2017
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26. Journalismus studieren in der Krise
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Thomas Hanitzsch, Corinna Lauerer, and Nina Steindl
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Communication. Mass media ,P87-96 - Abstract
Eine deutschlandweite Befragung von 556 Journalismus-Studierenden hat untersucht, ob und inwiefern sich die aktuelle Krise im Journalismus in der hochschulgebundenen Journalistenausbildung niederschlägt. Die Ergebnisse zeigen, dass unter den Studierenden keine ausgeprägte Krisenstimmung herrscht, auch wenn eine Mehrheit der Befragten die Zukunftschancen des Journalismus ambivalent bewertet. Die größten Herausforderungen für den Berufsstand werden in ökonomischen Faktoren sowie in verschlechterten Arbeitsbedingungen gesehen. Selbstverwirklichung und Idealismus haben angesichts der schwierigen Bedingungen einen entscheidenden Einfluss auf die Studienfachwahl. Darüber hinaus zeigt sich, dass trotz schwieriger Zeiten immer noch eine klare Mehrheit der Studierenden in den Journalismus möchte. Die Erfahrungen, die Studierende im redaktionellen Alltag machen, bestärkt sie dabei in ihrer Berufswahl und gibt ihnen zudem mehr Sicherheit hinsichtlich der Erreichbarkeit ihrer beruflichen Ziele. Gleichzeitig bereitet sich knapp die Hälfte der Studierenden im Geiste bereits darauf vor, in einem von beruflicher Mobilität gekennzeichneten Arbeitsmarkt irgendwann auch auf andere Tätigkeitsbereiche auszuweichen.
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- 2016
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27. Possibly Invasive New Bioenergy Crop Silphium perfoliatum: Growth and Reproduction Are Promoted in Moist Soil
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L. Marie Ende, Katja Knöllinger, Moritz Keil, Angelika J. Fiedler, and Marianne Lauerer
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bioenergy crop ,cup plant ,groundwater ,growth ,invasive potential ,reproductive potential ,Agriculture (General) ,S1-972 - Abstract
The cup plant (Silphium perfoliatum) is a new and promising bioenergy crop in Central Europe. Native to North America, its cultivation in Europe has increased in recent years. Cup plant is said to be highly productive, reproductive, and strongly competitive, which could encourage invasiveness. Spontaneous spread has already been documented. Knowledge about habitat requirements is low but necessary, in order to predict sites where it could spontaneously colonize. The present experimental study investigates the growth and reproductive potential of cup plant depending on soil moisture, given as water table distance (WTD). In moist soil conditions, the growth and reproductive potential of cup plant were the highest, with about 3 m plant height, 1.5 kg dry biomass, and about 350 capitula per plant in the second growing season. These parameters decreased significantly in wetter, and especially in drier conditions. The number of shoots per plant and number of fruits per capitulum were independent of WTD. In conclusion, valuable moist ecosystems could be at risk for becoming invaded by cup plant. Hence, fields for cultivating cup plant should be carefully chosen, and distances to such ecosystems should be held. Spontaneous colonization by cup plant must be strictly monitored in order to be able to combat this species where necessary.
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- 2021
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28. "Mein Urin ist lila - was ist denn da los?"
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Lauerer, Robert J. and Wilpert, Jochen
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- 2021
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29. Flow-Through Carbon Nanofiber-Based Transducer for Inline Electrochemical Detection in Paper-Based Analytical Devices.
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Perju, Antonia, Holzhausen, Ferdinand, Lauerer, Anna-Maria, Wongkaew, Nongnoot, and Baeumner, Antje J.
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- 2023
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30. Terra incognita Gewebespende: Ein systematischer Literaturreview zur Analyse institutioneller Einflussfaktoren auf die Bereitschaft zur Gewebespende.
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Kirchner, Katja, Lauerer, Michael, and Nagel, Eckhard
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- 2023
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31. Species- and developmental stage-specific effects of allelopathy and competition of invasive Impatiens glandulifera on co-occurring plants.
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Judith Bieberich, Marianne Lauerer, Maria Drachsler, Julian Heinrichs, Stefanie Müller, and Heike Feldhaar
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Medicine ,Science - Abstract
BACKGROUND:Impacts of invasive species on native communities are often difficult to assess, because they depend on a range of factors, such as species identity and traits. Such context-dependencies are poorly understood yet, but knowledge is required to predict the impact of invasions. MATERIALS AND METHODS:We assessed species- and developmental stage-specificity of competitive and allelopathic effects of the invasive plant Impatiens glandulifera on different developmental stages of four native plant species. While some studies have shown a reduction in plant growth caused by I. glandulifera, the magnitude of its impact is ambiguous. For our study we used seedlings and juveniles of I. glandulifera and the native target species Geum urbanum, Filipendula ulmaria, Urtica dioica, and Salix fragilis (seedlings only of the latter), which often co-occur with I. glandulifera in different habitats. Plants were grown in competition with I. glandulifera or treated with I. glandulifera leaf material, or 2-metoxy-1,4-naphtoquinone (2-MNQ), its supposedly main allelochemical. RESULTS AND CONCLUSIONS:Overall I. glandulifera had a negative effect on the growth of all target species depending on the species and on the plant's developmental stage. F. ulmaria was the least affected and U. dioica the most, and seedlings were less affected than juveniles. The species-specific response to I. glandulifera may lead to an altered community composition in the field, while growth reduction of seedlings and juveniles should give I. glandulifera an advantage in cases where plant recruitment is crucial. 2-MNQ led to minor reductions in plant growth, suggesting that it may not be the only allelopathic substance of I. glandulifera. Surprisingly, I. glandulifera was not fully tolerant to 2-MNQ. This autotoxicity could contribute to I. glandulifera population dynamics. We conclude that I. glandulifera reduces the growth of native vegetation and alters early successional stages without fully hindering it.
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- 2018
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32. Stable carbon and nitrogen isotope ratios of Eucalyptus and Acacia species along a seasonal rainfall gradient in Western Australia
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Schulze, E. D., Nicolle, D., Boerner, A., Lauerer, M., Aas, G., and Schulze, I.
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- 2014
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33. Balancing Efficiency and Inclusivity
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Lauerer, Corinna
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AbstractJournalism studies is facing a collaborative turn. The growing number of researchers collaborating not only increases the methodological complexity but also raises ethical challenges related to inclusivity. Not every collaborator is equally equipped and automatically benefits likewise from cooperation. This commentary argues that open science principles and practices help balancing efficiency and inclusivity in large-scale collaborative projects. First, the commentary draws on the Worlds of Journalism Studyas a source of experience to provide hands-on-solutions for researchers. It then identifies ways forward focusing on funding applications, pragmatic options for sharing methodological experiences, the h-index, and empirical insights into open science practices.
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- 2023
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34. Nitrogen uptake and utilisation as a competition factor between invasive Duchesnea indica and native Fragaria vesca
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Littschwager, Johanna, Lauerer, Marianne, Blagodatskaya, Evgenia, and Kuzyakov, Yakov
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- 2010
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35. Tobacco mutants with a decreased number of functional nia genes compensate by modifying the diurnal regulation of transcription, post-translational modification and turnover of nitrate reductase
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Scheible, Wolf-Rüdiger, González-Fontes, Agustín, Morcuende, Rosa, Lauerer, Marianne, Geiger, Michael, Glaab, Johanna, Gojon, Alain, Schulze, Ernst-Detlef, and Stitt, Mark
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- 1997
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36. Sicherung der Krankenhausversorgung: Innovative Dienstplanmodelle in der Pflege
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Andersch-Rupprecht, Claudia, Hinz, Florian, Lauerer, Michael, and Nagel, Eckhard
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- 2024
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37. Isolation, taxonomy and phylogeny of hyperthermophilic microorganisms
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Blöchl, E., Burggraf, S., Fiala, G., Lauerer, G., Huber, G., Huber, R., Rachel, R., Segerer, A., Stetter, K. O., and Völkl, P.
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- 1995
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38. Decreased ribulose-1,5-bisphosphate carboxylase-oxygenase in transgenic tobacco transformed with “antisense” rbcS: VI. Effect on photosynthesis in plants grown at different irradiance
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Lauerer, M., Saftic, D., Quick, W. P., Labate, C., Fichtner, K., Schulze, E. -D., Rodermel, S. R., Bogorad, L., and Stitt, M.
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- 1993
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39. Are Cumulus Cells Necessary for the Spontaneous Maturation of Germinal Vesicle-Stage Oocytes to Metaphase II
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Häberle, M., Scheurer, Ph., Lauerer, K., Fischer, M., and Hohl, M. K.
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- 1999
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40. Conceptualizing the early detection and intervention of infant mental health disorders in neonatal nursing.
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Gordon, Jessica M., Robidoux, Hannah, Gaffney, Kathy, Cirrito, Barbara L., and Lauerer, Joy A.
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- 2021
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41. The Visual Boundaries of Journalism: Native Advertising and the Convergence of Editorial and Commercial Content
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Ferrer-Conill, Raul, Knudsen, Erik, Lauerer, Corinna, and Barnoy, Aviv
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AbstractThis study investigates the visual objects that are used to either disclose or disguise the commercial nature of native advertising as news articles. We adopt a “material object” approach to explore the potential implications for journalism regarding transparency, trust, and credibility. Methodologically, this study used content analysis covering 21 publications in five countries: Germany, Israel, Norway, Spain, and Sweden. We analysed 373 individual native ads. The findings show that news outlets do not follow a consistent way to disclose native ads visually, negotiating the balance between transparency and deception. In this balance, news organizations do not boldly push for transparency and instead remain ambiguous. Our analyses show that both national and organizational characteristics matter when shaping the visual boundaries of journalism.
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- 2021
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42. Screen Time: The Impact of Digital Technology on Children and Strategies in Care
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Robidoux, Hannah, Ellington, Erin, and Lauerer, Joy
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Media and digital devices are an integral part of the world today. Despite potential benefits of media time, excessive or inappropriate use of technology is having a significant impact on the development and health of children. There is a relationship between increased screen time and greater risk of physical health complications, mental health concerns, and negative outcomes on cognitive, language, social, and emotional development. Successful evidence-based interventions and screening initiatives are available for reducing unhealthy media use in children. Providers need to be aware of media-use guidelines, screen for at-risk media use, and provide parental education as well as recommend interventions when indicated. [Media and digital devices are an integral part of the world today. Despite potential benefits of media time, excessive or inappropriate use of technology is having a significant impact on the development and health of children. There is a relationship between increased screen time and greater risk of physical health complications, mental health concerns, and negative outcomes on cognitive, language, social, and emotional development. Successful evidence-based interventions and screening initiatives are available for reducing unhealthy media use in children. Providers need to be aware of media-use guidelines, screen for at-risk media use, and provide parental education as well as recommend interventions when indicated. [Journal of Psychosocial Nursing and Mental Health Services, 57(11), 15–20.]
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- 2019
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43. Nursing leadership and influence in practice domains at a Veterans Affairs Health Care System.
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York, Janet A., Valvano, Mary, Hughes, Frederica, Sternke, Lisa Marie, Lauerer, Joy A., Baker, Jamie Anne, Edlund, Barbara, Reich, Kristina, and Pope, Charlene
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• Veteran disparities. • Leadership influence. • Psychiatric nursing residency. • VA nursing research. Studies in Veteran populations have examined disparities in health service use, care quality, outcomes and increased demands for behavioral health. The purpose is to describe the development of nursing leadership roles that influenced practice improvements and demonstrated outcomes related to health disparities in a Veterans Affairs (VA) population over a 12-year period. The Sundean and colleagues' concept analysis of nurse leadership influence was applied to frame the initiative process and impacts. Antecedents and processes that facilitated leadership development included mentorship, disparities expertise, partnerships, consultation, scholarship, dissemination, advocacy, education, and strong coauthor collaboration. Improvements and outcomes included access to services, improved health indicators, tools, workforce, funding, innovations, and nurse investigator studies, consistent with VA priorities and policy related to disparities and equity. Limitations and barriers were addressed. This initiative models' strategies to increase nurse leadership in health equity and care transformation in health systems and community practices. [ABSTRACT FROM AUTHOR]
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- 2023
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44. Apolipoprotein C-II-Defizienz im Säuglingsalter
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Lauerer, P, Steinmetz, M, Paul, T, Brockmann, K, and Seeliger, S
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ddc: 610 ,610 Medical sciences ,Medicine - Abstract
Eineitung: Apolipoprotein C-II-Defizienz ist eine sehr seltene autosomal-rezessiv vererbbare Stoffwechselerkrankung, die durch extrem erhöhte Serumkonzentrationen von Triglyceriden (bis 30.000 mg/dl) sowie Chylomikronen (milchig-rahmiges Serum) gekennzeichnet ist. Das Apo C-II-Gen liegt auf[for full text, please go to the a.m. URL], 60. Jahrestagung der Norddeutschen Gesellschaft für Kinder- und Jugendmedizin
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- 2011
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45. BNP and haematological parameters are markers of severity of Ebstein's anomaly: correlation with CMR and cardiopulmonary exercise testing
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Hosch, O., primary, Ngyuen, T.-T., additional, Lauerer, P., additional, Schuster, A., additional, Kutty, S., additional, Staab, W., additional, Unterberg-Buchwald, C., additional, Sohns, J. M., additional, Paul, T., additional, Lotz, J., additional, and Steinmetz, M., additional
- Published
- 2015
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46. The Total Right / Left - Volume - Index: A new and simplified CMR measure to evaluate the severity of Ebstein’s anomaly of the tricuspid valve
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Hösch, O., primary, Sohns, J., additional, Nguyen, T., additional, Lauerer, P., additional, Kowallick, J., additional, Unterberg, C., additional, Schuster, A., additional, Kutty, S., additional, Faßhauer, M., additional, Staab, W., additional, Paul, T., additional, Lotz, J., additional, and Steinmetz, M., additional
- Published
- 2014
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47. Journalismus in Deutschland
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Steindl, Nina, Lauerer, Corinna, and Hanitzsch, Thomas
- Abstract
Der vorliegende Aufsatz enthält Kernergebnisse einer repräsentativen Befragung von 775 Journalisten, die zu einer Bestandsaufnahme des Journalismus in Deutschland verdichtet werden. Im Vordergrund stehen soziodemographische Merkmale, Anstellungsverhältnisse, die Verteilung auf verschiedene Mediengattungen und Tätigkeitsbereiche sowie die wahrgenommene Autonomie und das berufliche Rollenverständnis. Die Ergebnisse zeigen, dass die Zahl der Journalisten weiter geschrumpft ist, wovon insbesondere hauptberufliche freie Journalisten betroffen sind. Zudem steigt das Durchschnittsalter deutscher Journalisten weiter an. Politisch stehen sie weiterhin eher im linksliberalen Spektrum. Die Daten deuten auch darauf hin, dass die Akademisierung des Berufs weiter fortschreitet. Der Anteil von Journalistinnen ist im Zeitvergleich weiter angestiegen, wobei in höheren Positionen immer noch weniger Frauen anzutreffen sind. Die Vergütungssituation ist für Journalistinnen und freie Journalisten besonders problematisch. Journalistinnen sind häufig bei Zeitschriften und im Rundfunk tätig, wohingegen Zeitungen, Nachrichtenagenturen sowie Mediendienste eher männlich dominiert sind. Zudem ist mehr als ein Viertel der Journalisten multimedial tätig. Die Mehrheit der Journalisten ist ressortgebunden und arbeitet zu speziellen Themen; die professionelle Autonomie ist in der Selbstwahrnehmung weiterhin sehr hoch. Nach wie vor ist das berufliche Selbstverständnis dominiert von einer neutralen Vermittlerrolle; diese Sicht hat während der vergangenen 20 Jahre sogar an Bedeutung gewonnen. Wichtiger geworden sind in den Augen der Journalisten auch die Bedürfnisse des Publikums sowie die Unterhaltungsrolle. Journalism has undergone profound challenges during the past decades. Especially, serious financial challenges and extensive technological change have been altering the profession. The resulting changes in journalism and in the conditions under which journalistic work takes place foster debates about a deprofessionalization as well as precarization and the dissolution of journalism’s boundaries. In the light of these developments, we aim to outline the current state of journalism in Germany. In order to take stock of the profession comprehensively, we present descriptive key findings on the sociodemographic backgrounds of journalists, their distribution across various types of media, employment conditions as well as journalists’ perceived autonomy and role conceptions. Furthermore, we compare the present data with previous studies on German journalists to give a first glimpse at the ongoing change in the journalistic world, from the perspective of German journalists. To mirror the German media landscape, we strived to interview a representative sample of journalists. Therefore, the first challenge was to evaluate the population of journalists in Germany and their distribution along the various kinds of media. By journalists, we are referring to professional journalists only, i. e. persons who are mainly working in journalism and earn at least 50% of their total income through journalistic activities. Based on an elaborate research and investigation process, we were able to undertake a qualified estimation of 41,250 journalists working in Germany, including approximately 9600 estimated freelance journalists. Comparing these numbers to previous studies, the first key finding of our investigation is that the population of journalists in Germany has continued to shrink, which is particularly true for freelancers whose main occupation is journalism. We suggest that economic challenges provide a convincing explanation for the decreasing number of journalists. The financial challenges in the media sector and global financial crises have led to an increase in unemployment during the past decades. At the same time, more and more freelancers are pursuing paid activities outside of journalism and, in doing so, are contributing to the debate about the dissolution of journalistic boundaries and its deprofessionalization. Another essential result from this first investigation process is that more than half of the journalists interviewed are still mainly working for the print media sector, another 26% in broadcasting media and only four percent in news agencies. However, the about 16% of journalists working in online media also reflect changes in the profession. Based on this information, we were able to select interviewees randomly in a two-step procedure. First, we chose newsrooms from an exhaustive list for each type of media (stratification criteria: reach, type of medium and ownership), and then selected journalists by a simple random sampling strategy. Between November 2014 and August 2015, these journalists were interviewed via telephone and online. Based on a sample of 775 German journalists, survey results show that the average age of journalists has increased. Respectively, also the average working experience is higher these days. Besides that, we found some gender specific differences among the interviewed journalists: The average age and working experience is lower among female journalists. The ratio of woman is the highest among young professionals, i. e. among journalists younger than 36. Because the proportion of young female journalists has grown during the past decades, we assume that woman have started to enter the profession increasingly. However, looking at the overall ratio of woman among German journalists, there is only a modest increase in the gender distribution. Further, women are still relatively rare in the higher echelons of editorial hierarchy. Female journalists work more often for magazines and broadcasters, while men dominate newspapers, news agencies and media services. Overall, the data further indicates an ongoing academization of the profession as more and more journalists hold a university degree. In contrast, we can observe continuity regarding the political orientations among journalists. It still leans toward the left end of the scale. Furthermore, one out of four journalists work for multiple media channels simultaneously. Especially, the combination of working for legacy media and the corresponding online outlet at the same time is widespread. About two thirds of the journalists are exclusively working for one newsroom. However, more than half of them produce journalistic content for two or three media outlets. Furthermore, we consider the majority of journalists as specialists (rather than generalists) since they indicated to work for specific news beats exclusively (e. g., on politics, health or sports). German journalists also still perceive their editorial autonomy to be very high. The role perception of journalists is rather stable but indicated interesting alterations: German journalists mainly think of themselves as neutral disseminators – a role that has grown in importance over the last 20 years. Likewise, the importance of meeting the expectations of the audience and entertaining the people has increased. Such an amplified orientation towards entertainment journalism confirms results of previous studies indicating that the media is striving for the observation of and interaction with the audience. Thus, it represents a change in the journalistic perception of the role of journalists. Overall, the present results clearly reflect both an ongoing change of the profession and a great deal of continuity. In conclusion, the classic role of information journalism continues to dominate while the societal, technological and media developments have hardly shaken the core of journalism.
- Published
- 2017
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48. A prism of excellence: The Charleston Veterans Administration Nursing Academic Partnership.
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Coxe, D. Nicole, Conner, Brian T., Lauerer, Joy, Skipper, Janice, York, Janet, Fraggos, Mary, and Stuart, Gail W.
- Abstract
Background The Veterans Administration (VA) has been committed to academic affiliate training partnerships for nearly 70 years in efforts to enhance veteran-centric health care. One such effort, the VA Nursing Academy (VANA) program, was developed in 2007 in response to the nationwide nursing shortage and began as a five-year pilot with funding competitively awarded to 15 partnerships between local VA medical centers and schools of nursing. The VANA program evolved into the VA Nursing Academic Partnership (VANAP) program following the initial pilot. Purpose This article describes the development and evolution of the Charleston VANAP, which includes the Ralph H Johnson VA Medical Center (RHJ VAMC) and the Medical University of South Carolina College of Nursing (MUSC CON). Methods The VA Office of Academic Affiliations (OAA) funded a large portion of the initial five years of the Charleston VANAP. Once the national funding source ceased, the RHJ VAMC and the MUSC CON entered into a Memorandum of Understanding (MOU) to offer in-kind contributions to the partnership. Discussion The Charleston VANAP is the only program in the nation to offer three different nurse trainee programs and this article highlights some of the more notable achievements from each program. Conclusion The Charleston VANAP is a comprehensive partnership between the RHJ VAMC and the MUSC CON that truly demonstrates a commitment to assure that the very best care be provided to Veterans, our Nation's heroes. [ABSTRACT FROM AUTHOR]
- Published
- 2016
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49. Major Depressive Disorder or Diabetes-Related Distress? Screening, Evaluation, and Treatment in Adults With Diabetes
- Author
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Sweatman, Christina, Lauerer, Joy A., Pruitt, Charlene, and Drayton, Shannon J.
- Abstract
Depression has long presented a challenge to successful diabetes management. As the burden of both diabetes and depression continue to rise, vigilant screening, early recognition, and prompt, effective treatments are imperative to help these patients achieve the best health outcomes. Symptoms of diabetes-related distress can mimic depression but must be differentiated from clinical depression because treatment approaches differ. Screening tools such as the World Health Organization Wellbeing Index, Diabetes Distress Scale 2, and Diabetes Distress Scale 17 guide the provider in making a distinction between these disorders. A combination treatment approach consisting of pharmacotherapy and psychotherapeutic interventions has consistently been shown to decrease the risk of complications and improve diabetes self-management skills.
- Published
- 2017
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50. Development of Veteran-Centric Competency Domains for Psychiatric–Mental Health Nurse Practitioner Residents
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York, Janet, Sternke, Lisa Marie, Myrick, Donald (Hugh), Lauerer, Joy, and Hair, Carole
- Published
- 2016
- Full Text
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