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1. Precise and fast control of the dissolved oxygen level for tumor-on-chip

Author

Charlotte Bouquerel, William César, Lara Barthod, Sarah Arrak, Aude Battistella, Giacomo Gropplero, Fatima Mechta-Grigoriou, Gérard Zalcman, Maria Carla Parrini, Marine Verhulsel, and Stéphanie Descroix

Subjects
Oxygen, Perfusion, Neoplasms, Biomedical Engineering, Cell Culture Techniques, Humans, Bioengineering, General Chemistry, Hypoxia, Biochemistry
Abstract

Oxalis features: independent control of pO2, pH and the liquid flowrate. pO2 equilibration time in the medium: 3 minutes. pO2 accuracy: 3 mmHg. Flowrate as low as 1 μL min−1 to avoid shear stress.

Published
2022

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