580 results on '"Lamkanfi, Mohamed"'
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2. Drugging the NLRP3 inflammasome: from signalling mechanisms to therapeutic targets
3. Protein citrullination and NET formation do not contribute to the pathology of A20/TNFAIP3 mutant mice
4. Infection history imprints prolonged changes to the epigenome, transcriptome and function of Kupffer cells
5. Regulated cell death in neutrophils: From apoptosis to NETosis and pyroptosis
6. Complex regulation of alarmins S100A8/A9 and secretion via gasdermin D pores exacerbates autoinflammation in familial Mediterranean fever
7. Dual neutrophil subsets exacerbate or suppress inflammation in tuberculosis via IL-1β or PD-L1
8. Nlrp2 deletion ameliorates kidney damage in a mouse model of cystinosis
9. Escherichia coli Rho GTPase-activating toxin CNF1 mediates NLRP3 inflammasome activation via p21-activated kinases-1/2 during bacteraemia in mice
10. Novel chemotype NLRP3 inhibitors that target the CRID3-binding pocket with high potency.
11. Neutrophil subsets play dual roles in tuberculosis by producing inflammasome dependent-IL-1β or suppressing T-cells via PD-L1
12. Drugging the NLRP3 inflammasome: from signalling mechanisms to therapeutic targets
13. The autoinflammation-associated NLRC4V341A mutation increases microbiota-independent IL-18 production but does not recapitulate human autoinflammatory symptoms in mice
14. Neutrophil subsets play dual roles in tuberculosis by producing inflammasome dependent-IL-1β or suppressing T-cells via PD-L1
15. Two distinct ubiquitin-binding motifs in A20 mediate its anti-inflammatory and cell-protective activities
16. Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis
17. Structure of S-layer protein Sap reveals a mechanism for therapeutic intervention in anthrax
18. How to dodge pyroptosis: lessons from Shigella flexneri
19. Single-cell analysis of pyroptosis dynamics reveals conserved GSDMD-mediated subcellular events that precede plasma membrane rupture
20. Caspases Leave the Beaten Track: Caspase-Mediated Activation of NF-κB
21. Regulation of the Expression and Processing of Caspase-12
22. General Strategies in Inflammasome Biology
23. Familial Mediterranean fever mutations lift the obligatory requirement for microtubules in Pyrin inflammasome activation
24. Data from IL1β Promotes Immune Suppression in the Tumor Microenvironment Independent of the Inflammasome and Gasdermin D
25. Supplementary Figures 1-11 from IL1β Promotes Immune Suppression in the Tumor Microenvironment Independent of the Inflammasome and Gasdermin D
26. Tuberculosis: The tug of war between pathogen and inflammasome
27. Apoptosis of intestinal epithelial cells restricts Clostridium difficile infection in a model of pseudomembranous colitis
28. Comment on: Effective ex vivo inhibition of cryopyrin-associated periodic syndrome (CAPS)-associated mutant NLRP3 inflammasome by MCC950/CRID3
29. The human inflammasomes
30. Flagellin-induced NLRC4 phosphorylation primes the inflammasome for activation by NAIP5
31. Critical role for inflammasome-independent IL-1β production in osteomyelitis
32. Salmonella exploits NLRP12-dependent innate immune signaling to suppress host defenses during infection
33. Does caspase-12 suppress inflammasome activation?
34. Inflammasomes as polyvalent cell death platforms
35. GSDMD drives canonical inflammasome‐induced neutrophil pyroptosis and is dispensable for NETosis
36. Caspase-1-driven neutrophil pyroptosis and its role in host susceptibility to Pseudomonas aeruginosa
37. An NLRP3 inflammasome-triggered Th2-biased adaptive immune response promotes leishmaniasis
38. Protective and detrimental roles of inflammasomes in disease
39. The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection
40. Regulation of immune pathways by the NOD-like receptor NLRC5
41. Dietary modulation of the microbiome affects autoinflammatory disease
42. Nonredundancy of IL-1α and IL-1β is defined by distinct regulation of tissues orchestrating resistance versus tolerance to infection
43. Nonredundancy of IL-1 alpha and IL-1 beta is defined by distinct regulation of tissues orchestrating resistance versus tolerance to infection
44. Immunology: Gut sensor halts viral attack
45. Pseudomonas aeruginosa infection reveals a Caspase-1-dependent neutrophil pyroptosis pathway that restrains damaging Histone release
46. Glyburide Inhibits the Cryopyrin/Nalp3 Inflammasome
47. Inflammasomes and intestinal tumorigenesis
48. The NOD-Like Receptor NLRP12 Attenuates Colon Inflammation and Tumorigenesis
49. The Nlrp3 inflammasome: contributions to intestinal homeostasis
50. NOD-like receptors and the innate immune system: Coping with danger, damage and death
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