19 results on '"LONG FORM"'
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2. Experimental Serious Games: Short Form Narrative in Augmented Reality Dioramas
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Marsh, Tim, Galbraith, Daniel, Jensen, Nathan, Hutchison, David, Series editor, Kanade, Takeo, Series editor, Kittler, Josef, Series editor, Kleinberg, Jon M., Series editor, Mattern, Friedemann, Series editor, Mitchell, John C., Series editor, Naor, Moni, Series editor, Pandu Rangan, C., Series editor, Steffen, Bernhard, Series editor, Terzopoulos, Demetri, Series editor, Tygar, Doug, Series editor, Weikum, Gerhard, Series editor, Alcañiz, Mariano, editor, Göbel, Stefan, editor, Ma, Minhua, editor, Fradinho Oliveira, Manuel, editor, Baalsrud Hauge, Jannicke, editor, and Marsh, Tim, editor
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- 2017
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3. L'ÉCRITURE BERGOUNIENNE À LA RECHERCHE D'ELLE-MÊM.
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JACQUET, MARIE THÉRÈSE
- Abstract
Copyright of Studia Universitatis Babes-Bolyai, Philologia is the property of Babes-Bolyai University, Cluj-Napoca, Romania and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2018
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4. Derivative Sport: The Journalistic Legacy of David Foster Wallace.
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Roiland, Josh
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JOURNALISTIC ethics ,SCHOLARSHIPS ,CREATIVE nonfiction ,PRESIDENTIAL elections - Abstract
The late writer David Foster Wallace is best known as the author of the 1,079-page novel Infinite Jest. But he also produced some of the most well known pieces of magazine journalism throughout the 1990s and 2000s. He was a three-time finalist for the National Magazine Award, winning once in 2001 for his Rolling Stone profile of Senator John McCain's presidential campaign, "The Weasel, Twelve Monkeys, and the Shrub." Because of his distinct voice, ability to blend high and low culture, and innovative use of footnotes, Wallace cast a long shadow of influence on a generation of literary journalists. In order to better understand the impact Wallace had on contemporary magazine writers, I spoke to his former editors, Colin Harrison and Joel Lovell, as well as current writers Maria Bustillos, Leslie Jamison, Michelle Orange, Jeff Sharlet, and John Jeremiah Sullivan about what it was like to work with him and how he influenced their own work. I've compiled those interviews into a kind of roundtable-style discussion that tells the story of Wallace and his contributions to literary journalism in the United States. (This piece, in slightly different form, was originally published on Longreads. [ABSTRACT FROM AUTHOR]
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- 2018
5. Cross-Language Mining for Acronyms and Their Completions from the Web
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Hahn, Udo, Daumke, Philipp, Schulz, Stefan, Markó, Kornél, Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Dough, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, Carbonell, Jaime G., editor, Siekmann, Jörg, editor, Hoffmann, Achim, editor, Motoda, Hiroshi, editor, and Scheffer, Tobias, editor
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- 2005
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6. Validation of the Simplified Chinese-character Version of the International Physical Activity Questionnaire-Long Form in Urban Community-dwelling Adults: a Cross-sectional Study in Hangzhou, China.
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REN, Yan Jun, SU, Meng, LIU, Qing Min, TAN, Ya Yun, DU, Yu Kun, LI, Li Ming, and LYU, Jun
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PEDOMETERS ,PHYSICAL activity ,EMPLOYMENT statistics ,RELIABILITY (Personality trait) - Abstract
Objective To assess the test-retest reliability and criterion validity of the Simplified Chinese-character version of the International Physical Activity Questionnaire Long form (IPAQ-L) in urban community-dwelling adults in Hanghzou, China. Methods A total of 158 eligible participants aged 25–59 years from 6 neighbourhoods in two central districts of Hangzhou completed the IPAQ-L questionnaire twice within a 7-day interval. Half of the subjects wore pedometers during the first 7 days. Test-retest reliability was examined by comparing the first (Day 1) and the second (Day 9) survey of IPAQ-L. Criterion validity was assessed by comparing IPAQ-L with pedometer data. Results Modest to good test-retest reliability was found with intraclass correlation coefficients of 0.67 for total PA, 0.37 to 0.73 for specific dimensions, and 0.56 to 0.71 for different intensities of PA. Total PA measured by IPAQ-L was moderately correlated with exercise levels (partial r = 0.27, P = 0.020) and walking distance (partial r = 0.31, P = 0.007), which were measured by a pedometer, after adjusting for gender, age, educational attainment and employment status. Conclusion Our results indicate that the IPAQ-L is a reliable and validated measure for assessing physical activity levels in this population and possibly the adult population in other mainland Chinese cities. [ABSTRACT FROM AUTHOR]
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- 2017
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7. Forms Less Solid: Duration and the Romantic Long Form
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Reese, Elizabeth
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- Romanticism, Formalism, Long Form, Temporality, Phenomenology, Duration
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Forms Less Solid argues that Romanticism’s long forms trouble established assumptions about literary form through their thematic representation and formal recreation of duration and phenomenological experience. The formalist history these texts work against makes two primary claims: first, that literary form is inherently atemporal and thus averse to length, and, second, that British Romanticism uniformly promotes that vision of form (and, by extension, that Romantic form is equivalent to the Romantic lyric). Forms Less Solid argues, instead, for the unique, extended temporality of the Romantic long form by reading four Romantic and post-Romantic long-form works of poetry and fiction. This project reads Charlotte Smith’s Beachy Head (1807), William Wordsworth’s The Excursion (1814), Elizabeth Barrett Browning’s Aurora Leigh (1856) and Sir Walter Scott’s The Antiquary (1816) as part of an alternative tradition that constructs length and duration as formal categories in their own right. These long forms employ what Forms Less Solid terms “durational modes”: postures, figures, or attitudes that represent in content the embodied, spatiotemporal nature of lived experience and, in turn, recreate and perform that experience on the level of form. Forms Less Solid argues that durational form is the method by which these texts formalize their own embeddedness in time and space, a feature that emerges only as a result of the prolonged engagement these texts require from their readers. The introductory first chapter details the converging literary and social histories of the late eighteenth and early nineteenth centuries (the prospect tradition, industrialization, and the development of the Greater Romantic Lyric) that gave rise to the Romantic long form, along with relevant scholarly contexts. Chapter Two, on Smith’s Beachy Head, argues that the poem’s formal and thematic expansiveness is replicated in its oscillations between scales of analysis, geographic elevations, and between main text and footnotes. That expansiveness is held in check by the poem’s equal and opposite emphasis on representing the limitations of embodied experience. This chapter also uses Smith’s Elegiac Sonnets (1784-1800) to demonstrate how Smith’s long form emerges out of her previous engagement with atemporal form. Chapter Three reads Wordsworth’s most “long and laborious” work, The Excursion, as a counterpoint to Wordsworth’s great period poems. The Excursion is a self-reflective text designed to make the reader confront its own structural composition in the time of reading. Chapter Four explores Aurora Leigh as a post-Romantic text that reworks certain Romantic renderings (here represented by Samuel Taylor Coleridge, Wordsworth, Percy Bysshe Shelley, and William Cowper) of the relationship between natural and domestic spaces. Aurora Leigh incorporates the gendered aspects of embodied experience into its protagonist’s development as a Poetess and into its own formal configuration. Chapter Five reads Scott’s The Antiquary as depicting a narrative time-sense that imitates the profession of its title and prioritizes local “accidents” over wholistic historical knowledge and narrative design. This chapter, as a result, reads The Antiquary as offering a formal and thematic counternarrative to Scott’s most famous and genre-defining novel, Waverley. The sixth and final chapter, a short coda, reflects briefly on the wider contemporary and personal contexts that have informed this project.
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- 2023
8. Widening of the genetic and clinical spectrum of Lamb-Shaffer syndrome, a neurodevelopmental disorder due to SOX5 haploinsufficiency
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Ashley N. Sigafoos, Salima El Chehadeh, Marcia C. Willing, Ela Akay, Florian Cherik, Anne-Marie E. Goyette, Vinodh Narayanan, Diane Masser-Frye, Catherine Karimov, Rhonda E. Schnur, Rebekah Bressi, Rhys H. Thomas, Gary D. Clark, Tina Barbaro-Dieber, Jill A. Rosenfeld, Carlos A. Bacino, Maria J. Guillen Sacoto, Laura Russell, Kristin Lindstrom, Caroline Schluth-Bolard, Xia Wang, Yvonne Hilhorst-Hofstee, Marcelo Vargas, Zehua Zhu, Ash Zawerton, Boris Keren, Mariëtte J.V. Hoffer, Isabelle Marey, Alice Poisson, Daphné Lehalle, Maries Joseph, Gaetan Lesca, Simon Zwolinski, Laurence Perrin, Rhoda Akilapa, Emilia K. Bijlsma, Christel Depienne, Amélie Piton, Claire G. Salter, Lucie Dupuis, Daryl A. Scott, Jolien S. Klein Wassink-Ruiter, Benjamin Cogné, Mathilde Nizon, Richard Chang, Kirsty McWalter, Myriam Srour, Perrine Charles, Anne-Claude Tabet, Natalie Canham, Sylvie Odent, Caroline Nava, Karl J. Clark, Elizabeth J. Bhoj, Jonathan Levy, Keri Ramsey, Yves Alembik, Lucia Ortega, Sophie Dupuis-Girod, Shoji Ichikawa, Christine Francannet, Marta Bertoli, Christèle Dubourg, Eric W. Klee, Ange-Line Bruel, Sebastien Moutton, Emily Fassi, Anthony Vandersteen, Abdul Haseeb, Antonina Wojcik, Patrick R. Blackburn, Lynne M. Bird, Patrick Rump, Véronique Lefebvre, Alma Kuechler, Sophie Nambot, Keren Machol, Cyril Mignot, Andreas Hartmann, Rossana Sanchez Russo, Erica H. Gerkes, Sylvie Jaillard, Roberto Mendoza-Londono, Trevor Cole, Pauline Monin, Cleveland Clinic, Institut du Cerveau et de la Moëlle Epinière = Brain and Spine Institute (ICM), Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Service de Génétique Cytogénétique et Embryologie [CHU Pitié-Salpêtrière], CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Génétique humaine et fonctions cognitives - Human Genetics and Cognitive Functions (GHFC (UMR_3571 / U-Pasteur_1)), Institut Pasteur [Paris]-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Département de génétique [Robert Debré], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-AP-HP Hôpital universitaire Robert-Debré [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Centre de recherche en neurosciences de Lyon (CRNL), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet [Saint-Étienne] (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Hospices Civils de Lyon (HCL), Centre d'Etude et de Recherche Multimodal Et Pluridisciplinaire en imagerie du vivant (CERMEP - imagerie du vivant), Université de Lyon-Université de Lyon-CHU Grenoble-Hospices Civils de Lyon (HCL)-CHU Saint-Etienne-Université Jean Monnet [Saint-Étienne] (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA), Lipides - Nutrition - Cancer [Dijon - U1231] (LNC), Université de Bourgogne (UB)-Institut National de la Santé et de la Recherche Médicale (INSERM)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement, Centre de génétique - Centre de référence des maladies rares, anomalies du développement et syndromes malformatifs (CHU de Dijon), Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand (CHU Dijon), Institut de Génétique et Développement de Rennes (IGDR), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Centre National de la Recherche Scientifique (CNRS)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), CHU Pontchaillou [Rennes], Institut de recherche en santé, environnement et travail (Irset), Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )-Institut National de la Santé et de la Recherche Médicale (INSERM)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Université d'Angers (UA), Center for Human and Clinical Genetics, Leiden University Medical Center (LUMC), Service de génétique médicale - Unité de génétique clinique [Nantes], Université de Nantes (UN)-Centre hospitalier universitaire de Nantes (CHU Nantes), unité de recherche de l'institut du thorax UMR1087 UMR6291 (ITX), Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Department of Health Sciences Research [Mayo Clinic] (HSR), Mayo Clinic, This research was funded in part by the Agence Nationale de la Recherche and European High-Functioning Autism Network (ANR EUHFAUTISM), the Assistance Publique–Hôpitaux de Paris (AP-HP), the Institut National de la Santé et de la Recherche Médicale (INSERM), the BioPsy labex (to Christel Depienne and C.N.) and the Association Française du Syndrome Gilles de la Tourette (AFSGT) to Christel Depienne. It was also funded by the Cleveland Clinic Lerner Research Institute (LRI Chair’s Innovative Research Award to V.L.), and by Harper’s Quest and the LAMSHF Syndrome Research Fund (donations to V.L.) and the Center for Individualized Medicine, Mayo Clinic. This study makes use of data generated by the DECIPHER community and the Deciphering Developmental Disorders (DDD) Study, which is funded by the Wellcome Trust. The DDD study presents independent research commissioned by the Health Innovation Challenge Fund (grant number HICF-1009-003), a parallel funding partnership between Wellcome and the Department of Health, and the Wellcome Sanger Institute (grant number WT098051). The views expressed in this publication are those of the author(s) and not necessarily those of Wellcome or the Department of Health. The study has UK Research Ethics Committee approval (10/H0305/83, granted by the Cambridge South REC, and GEN/284/12 granted by the Republic of Ireland REC). The research team acknowledges the support of the National Institute for Health Research, through the Comprehensive Clinical Research Network., We thank the patients and their families for their participation in this study, and the C4RCD Research Group (Newell Belnap, Amanda Courtright, Ana Claasen, David Craig, Matt Huentelman, Madison LaFleur, Sampathkumar Rangasamy, Ryan Richholt, Isabelle Schrauwen, Ashley L. Siniard, and Szabolics Szelinger) for providing clinical information on patient P18., Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [APHP]-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Service de Génétique et Cytogénétique [CHU Pitié-Salpêtrière], Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-CHU Pitié-Salpêtrière [APHP], Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-AP-HP Hôpital universitaire Robert-Debré [Paris], Centre d'Exploration et de Recherche Médicales par Émission de Positons (CERMEP), Université Joseph Fourier - Grenoble 1 (UJF)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-CHU Grenoble-Hospices Civils de Lyon (HCL)-CHU Saint-Etienne-Université Jean Monnet [Saint-Étienne] (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Université de Bourgogne (UB)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Institut National de la Santé et de la Recherche Médicale (INSERM), Université d'Angers (UA)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), and Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)
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Male ,Medizin ,Haploinsufficiency ,L-SOX5 ,VARIANTS ,0302 clinical medicine ,Neurodevelopmental disorder ,Intellectual disability ,Missense mutation ,2.1 Biological and endogenous factors ,Aetiology ,Child ,Genetics (clinical) ,Genetics ,Pediatric ,Genetics & Heredity ,0303 health sciences ,Pedigree ,FAMILY ,DNA-Binding Proteins ,developmental delay ,TRANSCRIPTION FACTORS ,Phenotype ,intellectual disability ,Child, Preschool ,missense variants ,Female ,SOXD Transcription Factors ,Adult ,EXPRESSION ,Adolescent ,Intellectual and Developmental Disabilities (IDD) ,Clinical Sciences ,Mutation, Missense ,autism ,Cell fate determination ,Biology ,LONG FORM ,SEQUENCE ,Article ,03 medical and health sciences ,Young Adult ,Rare Diseases ,Clinical Research ,CARTILAGE ,Intellectual Disability ,medicine ,Animals ,Humans ,Language Development Disorders ,Genetic Predisposition to Disease ,Preschool ,Transcription factor ,Gene ,030304 developmental biology ,[SDV.GEN]Life Sciences [q-bio]/Genetics ,MUTATIONS ,Human Genome ,Infant ,medicine.disease ,Brain Disorders ,Neurodevelopmental Disorders ,Deciphering Developmental Disorder Study ,Mutation ,Autism ,epilepsy ,Missense ,030217 neurology & neurosurgery ,GENERATION - Abstract
International audience; PURPOSE: Lamb-Shaffer syndrome (LAMSHF) is a neurodevelopmental disorder described in just over two dozen patients with heterozygous genetic alterations involving SOX5, a gene encoding a transcription factor regulating cell fate and differentiation in neurogenesis and other discrete developmental processes. The genetic alterations described so far are mainly microdeletions. The present study was aimed at increasing our understanding of LAMSHF, its clinical and genetic spectrum, and the pathophysiological mechanisms involved.METHODS: Clinical and genetic data were collected through GeneMatcher and clinical or genetic networks for 41 novel patients harboring various types of SOX5 alterations. Functional consequences of selected substitutions were investigated.RESULTS: Microdeletions and truncating variants occurred throughout SOX5. In contrast, most missense variants clustered in the pivotal SOX-specific high-mobility-group domain. The latter variants prevented SOX5 from binding DNA and promoting transactivation in vitro, whereas missense variants located outside the high-mobility-group domain did not. Clinical manifestations and severity varied among patients. No clear genotype-phenotype correlations were found, except that missense variants outside the high-mobility-group domain were generally better tolerated.CONCLUSIONS:This study extends the clinical and genetic spectrum associated with LAMSHF and consolidates evidence that SOX5 haploinsufficiency leads to variable degrees of intellectual disability, language delay, and other clinical features.
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- 2020
9. A sparser, speedier reshape.
- Author
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Simons, Kenneth L.
- Subjects
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MISSING data (Statistics) , *DATA management - Abstract
A new command, sreshape, supports sparse and speedy reshaping of data. Often reshaped data are "sparse" in the sense of containing many missing values that are dropped after reshaping. sreshape automates the process of reshaping and dropping such missing information to avoid potential errors and, for both sparse and nonsparse data, yields speed improvements. Using large test datasets, sreshape achieves identical results to reshape 8 to 31 times faster in wide-to-long reshapes and 2 to 13 times faster in long-to-wide reshapes. Further suggested improvements may allow StataCorp to increase these speed gains in the built-in version. [ABSTRACT FROM AUTHOR]
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- 2016
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10. Correlates of Agreement between Accelerometry and Self-reported Physical Activity.
- Author
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Cerin, Ester, Cain, Kelli L., Oyeyemi, Adewale L., Owen, Neville, Conway, Terry L., Cochrane, Tom, Van Dyck, Delfien, Schipperijn, Jasper, MitÁŠ, Josef, Toftager, Mette, Aguinaga-Ontoso, Ines, and Sallis, James F.
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AGE distribution , *BODY weight , *EXERCISE physiology , *QUESTIONNAIRES , *SELF-evaluation , *SEX distribution , *EDUCATIONAL attainment , *ACCELEROMETRY , *SEDENTARY lifestyles , *PHYSICAL activity ,RESEARCH evaluation - Abstract
Purpose: Understanding factors that influence accurate assessment of physical activity (PA) and sedentary behavior (SB) is important to measurement development, epidemiologic studies, and interventions. This study examined agreement between self-reported (International Physical Activity Questionnaire--Long Form [IPAQ-LF]) and accelerometry-based estimates of PA and SB across six countries and identified correlates of between-method agreement. Methods: Self-report and objective (accelerometry-based) PA and SB data were collected in 2002-2011 from 3865 adult participants in eight cities from six countries (Belgium, Czech Republic, Denmark, Spain, United Kingdom, and United States). Between-method relative agreement (correlation) and absolute disagreement (mean difference between conceptually and intensity-matched IPAQ-LF and accelerometry-based PA and SB variables) were estimated. Also, sociodemographic characteristics and PA patterns were examined as correlates of between-method agreement. Results: Observed relative agreement (relationships of IPAQ-LF with accelerometry-based PA and SB variables) was small to moderate (r = 0.05-0.37) and was moderated by sociodemographic (age, sex, weight status, and education) and behavioral (PA-type) factors. The absolute disagreement was large, with participants self-reporting higher PA intensity and total time in moderate-to-vigorous-intensity PA than accelerometry. Also, self-reported sitting time was lower than accelerometry-based sedentary behavior. After adjusting for sociodemographic and behavioral factors, the absolute disagreement between pairs of IPAQ-LF and accelerometry-based PA variables remained significantly different across cities/countries. Conclusions: Present findings suggest systematic cultural and/or linguistic and sociodemographic differences in absolute agreement between the IPAQ-LF and the accelerometry-based PA and SB variables. These results have implications for the interpretation of international PA and SB data and correlate/determinant studies. They call for further efforts to improve such measures. [ABSTRACT FROM AUTHOR]
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- 2016
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11. Beş Faktör Kişilik Ölçeğinin Kısa Formunun geliştirilmesi.
- Author
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TATAR, Arkun
- Abstract
Objective: Five Factor Personality Inventory, when used in large samples for screening purposes may lead to difficulties and unhealthy results because of its length. The inventory contains 220 items and designed to assess five factors and seventeen sub dimensions. However, when only five factors need to be evaluated, administration of the long form of the inventory causes loss of time, effort and economic value. For this reason this study aims to develop a short form of the inventory to assess only the five factors of the scale. Methods: The data of the normative sample of 5239 participants of the inventory was divided into two. The first half consisting of 2000 participants was used for the selection of items, and the second half consisting of 3239 participants was used for cross validity study. The short form constructed was administered to a sample of 1518 participants as a third study. The results of the first two studies were compared with the data of the third study. Results: Out of the long form of the inventory 76 items for the five factors, 6 items for the social desirability dimension and 3 items as control items were selected by using item response theory. Various methods were used to determine the validity of the short form, and the correlations between the long and the short forms. High correlation coefficients were found for each of the factors of the long and the short forms in each of the three analyses of data. Structural validity of the short form was shown by explanatory and confirmatory factor analysis. Reliability values of the short form were close to the values of the long form in all of the studies. Test retest correlation coefficients of the short form were also high. All of the results showed very close factor values. Conclusion: It was seen that the developed short form of 85 items complied with five factor model and also protected the structure of the long form. Many strong correlations between the two forms showed that the short form represents the long form. [ABSTRACT FROM AUTHOR]
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- 2016
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12. A novel compound heterozygous leptin receptor mutation causes more severe obesity than in Lepr
- Author
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Claudia Berger, Matthias Blüher, Janet Kelso, Nora Klöting, Henrike O. Heyne, Esther Guiu-Jurado, Tina Heiland, Peter Kovacs, Sebastian Dommel, Steffen Roßner, Michael Dannemann, Corinna Höfling, Jana Lorenz, and Institute for Molecular Medicine Finland
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obesity ,LIVER ,Mapk, mitogen-activated protein kinase ,QTL, quantitative trait locus ,Adipose tissue ,Mice, Obese ,MOUSE ,Compound heterozygosity ,medicine.disease_cause ,Biochemistry ,ACTIVATION ,genetic background ,Mice ,Lepr, leptin receptor ,0302 clinical medicine ,Endocrinology ,Hyperinsulinemia ,Jak, Janus kinase ,leptin receptor mutation ,2. Zero hunger ,0303 health sciences ,Mutation ,Leptin ,DEFICIENCY ,LH, lateral hypothalamic area ,DM, dorsomedial hypothalamic nucleus ,PVN, paraventricular hypothalamic nucleus ,Receptors, Leptin ,Lepr ,Compound Heterozygous ,Genetic Background ,Leptin Receptor Mutation ,Obesity ,Research Article ,EXPRESSION ,medicine.medical_specialty ,Mice, Transgenic ,QD415-436 ,Biology ,Quantitative trait locus ,LONG FORM ,EARLY-ONSET OBESITY ,03 medical and health sciences ,Stat, signal transducers and activators of transcription ,Internal medicine ,AT, adipose tissue ,medicine ,Animals ,sc, subcutaneous ,030304 developmental biology ,compound heterozygous ,Leptin receptor ,IDENTIFICATION ,Cell Biology ,medicine.disease ,GENE ,epi, epigonadal ,Mice, Inbred C57BL ,VMN, ventromedial hypothalamus ,Chromosome 4 ,BC, backcross ,1182 Biochemistry, cell and molecular biology ,ADCY3, adenylate cyclase 3 ,030217 neurology & neurosurgery ,GENERATION - Abstract
The leptin receptor (Lepr) pathway is important for food intake regulation, energy expenditure and body weight. Mutations in leptin and the Lepr have been shown to cause early-onset severe obesity in mice and humans. In studies with C57BL/6NCrl mice, we found a mouse with extreme obesity. To identify a putative spontaneous new form of monogenic obesity, we performed backcross studies with this mouse followed by a quantitative trait locus (QTL) analysis and sequencing of the selected chromosomal QTL region. We thereby identified a novel Lepr mutation (C57BL/6N-LeprL536Hfs∗6-1NKB), which is located at chromosome 4, exon 11 within the CRH2-leptin binding site. Compared to C57BL/6N mice, LeprL536Hfs∗6 develop early onset obesity and their body weight exceeds that of Leprdb/db mice at an age of 30 weeks. Similar to Leprdb/db mice, the LeprL536Hfs∗6 model is characterized by hyperphagia, obesity, lower energy expenditure and activity, hyperglycemia, and hyperinsulinemia compared to C57BL/6N mice. Crossing Leprdb/wt with LeprL536Hfs∗6/wt mice results in compound heterozygous LeprL536Hfs∗6/db mice, which develop even higher body weight and fat mass than both homozygous Leprdb/db and LeprL536Hfs∗6 mice. Our study suggests that the phenotype of monogenic Lepr deficient mice depends on the molecular localization of the Lepr mutation. Compound heterozygous Lepr deficiency affecting functionally different regions of the Lepr causes more severe obesity than the parental homozygous mutations.
- Published
- 2021
13. Tarihsel ve teorik açıdan adalet dairesinin uzun formu
- Author
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İlker Kömbe
- Subjects
Long Form ,media_common.quotation_subject ,Arts in general ,Social Sciences ,Metaphysics ,Ṣırr al-aṣrār ,NX1-820 ,Economic Justice ,Politics ,Sırru’l-esrar ,State (polity) ,Adalet Dairesi ,Sociology ,Meaning (existential) ,Circle of Justice ,Function (engineering) ,Ṣırrü’l-esrār ,Sırrü’l-esrâr ,media_common ,Düzen ,Language and Literature ,Political Thought ,Islam ,Epistemology ,Uzun Form ,Siyaset Düşüncesi ,Order ,Period (music) - Abstract
Kitap bölümü olarak yazılan bu makalede, ortaçağ İslâm siyaset düşüncesini oluşturan pek çok siyaset türünde kaleme alınmış olan kitapların hem muhtevaları hem de bölüm başlıkları açısından en temel, en önemli ve en merkezi kavramı olan adalet dairesi, yalnızca uzun formu dikkate alınmak koşuluyla, başlangıcından Osmanlı dönemine ait XVI. yüzyılın sonuna kadarki bir dönemle sınırlı kalacak biçimde, söz konusu olan kavramın tarihsel süreci ve teorik arka planı veya ilkeleri olmak üzere, iki bakımdan, ele alınarak incelenmeye ve değerlendirilmeye gayret edilecektir. Tarihsel süreci açısından bakıldığında, birinci olarak, adalet dairesinin uzun formunun yer aldığı ilk kaynak ve uzun formun ortaçağ İslâm siyaset düşüncesine ne şekilde ya da hangi yolla geçtiği tespit edilmeye ve bu tespitin ne anlama geldiği, bir başka ifadeyle, bu tespitten çıkan sonuç gösterilmeye çalışılacaktır. İkinci olarak, ortaçağ İslâm siyaset düşüncesinin altında yer alan çeşitli siyaset türlerinde adalet dairesinin uzun formuna yer veren kaynaklar, bu kaynakların yazıldıkları devletler ve coğrafyalar ile uzun formun nispet edildiği şahıslar ve temel unsurları ifade edilecektir. Kavramın Teorik arka planı veya dayanağı olan ilkeler açısından bakıldığında ise, birinci olarak, merkezî bir siyaset düşüncesi kavramı olan adalet dairesinin uzun formunun ilkeleri temellendirilmeye ve bu ilkelerin, Yeni Platoncu felsefe çerçevesinde kabul edilebilecek olan Meşşaî felsefenin klâsik bilişsel yahut rasyonel psikolojiye karşılık gelen nefs teorisi, ahlâk felsefesi, doğa felsefesi, evren ve kozmoloji anlayışı ile metafizikten nasıl kaynaklandığı gösterilmeye çalışılacaktır. Son olarak ise, adalet dairesinin uzun formunun, ilişkili olduğu devlet ve toplum düzeni ve yapısı ile bu devlet ve toplum yapısı ve düzeni içindeki önemi, anlamı ve işlevi analiz edilecektir. In this study or article, we will try to analyze and evaluate the long form of circle of justice which is the basic, importance and central concept of different kinds of politics that belong to Islamic political thought in terms of historical background and theoretical or philosophical principles from beginning to end of sixteenth century of Ottoman period. From a historical perspective, firstly, we will try to determine the first book that the long form of circle of justice is found in it and afterwards we will try to show how the long form introduced into Islamic political thought externally. Secondly, we will try to explain and show the different and several Islamic political works that discuss and explain the long form and its main elements as well as the different and several states and regions in which they were written. From a theoretical or philosophical perspective, firstly, we will try to analyze the basic principles of the long form which is the central concept of political thought. Secondly, we will try to show how its principles are derived from the classical psychological and ethical philosophy and view of nature as well as cosmology and metaphysics of Meşşai philosophy that can be found acceptable in the extent of Neo Platonic philosophy. Finally, we will try to explain the kind of political thought, state and society that the long form belongs them and the meaning, importance and function of the long form in the structure and order of the state and society.
- Published
- 2021
14. So you want to write about libraries?
- Author
-
Brett Bonfield
- Subjects
about us ,library databases ,long form ,publishing ,Bibliography. Library science. Information resources - Abstract
In the Library with the Lead Pipe is a little over a year old now. We published our first article on October 8, 2008, and we’ve now published thirty-five in all, along with five group posts. By most measures, we’re still a new publication, but we’ve also been pretty successful. About 2,250 people subscribe to [...]
- Published
- 2009
15. The Obesity in Bilateral Ovariectomized Rats Is Related to a Decrease in the Expression of Leptin Receptors in the Brain
- Author
-
Kimura, Mitsuhiro, Irahara, Minoru, Yasui, Toshiyuki, Saito, Seiichiro, Tezuka, Michiko, Yamano, Shuji, Kamada, Masaharu, and Aono, Toshihiro
- Subjects
- *
LEPTIN , *OBESITY in animals - Abstract
We investigated the expression levels of leptin receptors in the brain of ovariectomized (OVX) rats. The mean expression level of ob mRNA in adipose tissues of OVX rats was significantly (P < 0.01) lower than that in the SHAM operation group rats, and the mean body weight of OVX rats was significantly (P < 0.01) greater than that in the SHAM group rats. However, there were no differences between serum leptin concentrations in these two groups. The mean level of leptin receptor (OB-R) mRNA expression in the brain tissue and the mean level of long form type OB-R (OB-RL) mRNA expression in the hypothalamus of the OVX rats were significantly (P < 0.05) lower than those in the SHAM group rats. These changes were cancelled by supplementation with 17 β-estradiol in OVX rats. These results suggested that not only changes in the expression level of ob mRNA in adipose tissue and the serum leptin concentration but also changes in the OB-R mRNA in the brain are involved in the body weight increase in OVX rats and that a decrease in OB-R makes transmission of signals to suppress the amount of food intake difficult, thus leading to an increase in body weight. [Copyright &y& Elsevier]
- Published
- 2002
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16. Take five: how Sports Illustrated and L’Équipe redefine the long-form sports journalism genre
- Author
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Christopher D. Tulloch and Xavier Ramon
- Subjects
Sourcing ,business.industry ,Sports journalism ,Communication ,05 social sciences ,Agenda ,050801 communication & media studies ,Public relations ,Key issues ,0508 media and communications ,Consolidation (business) ,Multimedia ,Long form ,0502 economics and business ,Journalism ,Sociology ,User interface ,Sport management ,business ,Brand-building ,050212 sport, leisure & tourism - Abstract
The consolidation of the counter genre that is long-form sports journalism (LFSJ) is of growing interest to the sports media researcher. In order to trace its expansion across the sports journalism landscape, this article offers a comparative transatlantic case study featuring the entire collection of long-form stories developed by two prestigious publications: the American magazine Sports Illustrated (SI Longform) and the French sports daily L’Equipe (L’Equipe Explore). The study considers the slow journalism heritage of LFSJ and its challenge to established Web interface theology while exploring key issues such as the sports agenda, sourcing and the use of immersive multimedia formats, aimed at improving the sporting culture of its users. The article concludes by considering the pivotal role of LFSJ in the brand-building strategies of the media outlets themselves.
- Published
- 2017
17. Expression of Long-form N-Acetylglucosamine-6-O-Sulfotransferase 1 in Human High Endothelial Venules
- Author
-
Yasuhiro Sakai, Minoru Fukuda, Maiko Fujiwara, Tsutomu Nakada, Hitomi Hoshino, Jun Nakayama, Motohiro Kobayashi, Kenji Uchimura, and Junya Masumoto
- Subjects
Histology ,Blotting, Western ,Molecular Sequence Data ,High endothelial venules ,Fluorescent Antibody Technique ,Golgi Apparatus ,Biology ,Immunofluorescence ,Antibodies ,high endothelial venule (HEV) ,Venules ,medicine ,Humans ,Amino Acid Sequence ,Lymphocyte homing receptor ,Peptide sequence ,Base Sequence ,medicine.diagnostic_test ,long form ,Articles ,Molecular biology ,Blot ,Open reading frame ,Cytochemistry ,biology.protein ,Endothelium, Vascular ,Lymph Nodes ,N-acetylglucosamine-6-O-sulfotransferase 1 (GlcNAc6ST-1) ,Sulfotransferases ,Anatomy ,Antibody ,HeLa Cells - Abstract
Two members of the N-acetylglucosamine-6-O-sulfotransferase (GlcNAc6ST) family, GlcNAc6ST-1 and GlcNAc6ST-2, function in the biosynthesis of 6-sulfo sialyl Lewis X-capped glycoproteins expressed on high endothelial venules (HEVs) in secondary lymphoid organs. Thus, both enzymes play a critical role in L-selectin-expressing lymphocyte homing. Human GlcNAc6ST-1 is encoded by a 1593-bp open reading frame exhibiting two 5' in-frame methionine codons spaced 141 bp apart. Both resemble the consensus sequence for translation initiation. Thus, it has been hypothesized that both long and short forms of GlcNAc6ST-1 may be present, although endogenous expression of either form has not been confirmed in humans. Here, the authors developed an antibody recognizing amino acid residues between the first two human GlcNAc6ST-1 methionines. This antibody specifically recognizes the long form of the enzyme, a finding validated by Western blot analysis and immunofluorescence cytochemistry of HeLa cells misexpressing long and/or short forms of human GlcNAc6ST-1. Using this antibody, the authors carried out immunofluorescence histochemistry of human lymph node tissue sections and found endogenous expression of the long form of the enzyme in human tissue, predominantly in the trans-Golgi network of endothelial cells that form HEVs. (J Histochem Cytochem 60:397-407, 2012), Article, JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY. 60(5):397-407 (2012)
- Published
- 2012
18. Immediacy In Comedy: How Gertrude Stein, Long Form Improv, And 5 Second Films Can Revolutionize The Comedic Form
- Author
-
Hluch, Alexander
- Subjects
- Comedy, immediacy, improv, long form, theatre, gertrude stein, theater, harold, film, digital short, 5 second films, drama, Acting, Theatre and Performance Studies, Arts and Humanities -- Dissertations, Academic, Dissertations, Academic -- Arts and Humanities
- Abstract
Comedy has typically been derided as second-tier to drama in all aspects of narrative. Throughout history, comedy has seen short shrift in both critical reception and academic investigation. Merit is simply placed on drama far before that of comedy. This is not for comedy’s own lack of skill or craft, but simply for comedy’s misappropriation as a narrative form. Throughout the years, by way of either competition or economic superiority, comedy has been pigeonholed into the typified dramatic structure that drama so thoroughly encapsulates. Being forced into a form that exemplifies complex, climactic structure and explicit character development, comedy in its purest form has suffered through the ages. Gertrude Stein’s theory of Landscape Drama, and, more specifically, immediacy, is best attuned to comedy in its truest form. Comedy does not require sweeping character development, obtuse narrative design, or fantastic spectacle to produce superior works of art. Comedy, when compared to drama, exists best in a much more punctuated format. Stein’s theories, while never intended for comedy, align absolutely perfectly with the comedic genre’s design. And epitomized through long form improv on the stage, and the newly-fashioned digital short made profitable by the proliferation of the internet and digital culture, comedy’s purest form has become more readily available as narrative has progressed throughout history. With this thesis, I intend to display the disparity between comedy and drama due to comedy’s misallotment into a format that does not properly encapsulate it to its most fulfilling embodiment. Through this display, I seek to uncover the debt done to the comedic form from centuries of neglect in academic query and merit in order to best prove comedy’s need for ii critical scrutiny. Further, in doing so I hope to better construe a community of comedic research and criticism in order to create better art and more diverse comedic offerings.
- Published
- 2013
19. From Busting A-Rod to Building Apps.
- Author
-
Boudway, Ira
- Subjects
APPLICATION software ,SPORTS - Abstract
The article offers information on Roopstigo, an application for both Apple and Android devices that will feature long-form sports journalism, launched by Selena Roberts.
- Published
- 2012
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