177 results on '"Kurti, Aishe"'
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2. Brain-targeting liposome-based APOE2 gene delivery exacerbates soluble amyloid-β accumulation in AppNL−G-F mice
3. Cell-autonomous effects of APOE4 in restricting microglial response in brain homeostasis and Alzheimer’s disease
4. Correction: Trem2 H157Y increases soluble TREM2 production and reduces amyloid pathology
5. Peripheral apoE4 enhances Alzheimer’s pathology and impairs cognition by compromising cerebrovascular function
6. C9ORF72 poly(GA) aggregates sequester and impair HR23 and nucleocytoplasmic transport proteins
7. Heterochromatin anomalies and double-stranded RNA accumulation underlie C9orf72 poly(PR) toxicity
8. Loss of clusterin shifts amyloid deposition to the cerebrovasculature via disruption of perivascular drainage pathways
9. Investigating the Pathogenic Interplay of Alpha-Synuclein, Tau, and Amyloid Beta in Lewy Body Dementia: Insights from Viral-Mediated Overexpression in Transgenic Mouse Models
10. Clusterin ameliorates tau pathology in vivo by inhibiting fibril formation
11. Astrocyte-derived clusterin suppresses amyloid formation in vivo
12. Loss of Tmem106b exacerbates FTLD pathologies and causes motor deficits in progranulin‐deficient mice
13. Poly(GR) impairs protein translation and stress granule dynamics in C9orf72-associated frontotemporal dementia and amyotrophic lateral sclerosis
14. Enhanced phosphorylation of T153 in soluble tau is a defining biochemical feature of the A152T tau risk variant
15. LRP1 in vascular mural cells modulates cerebrovascular integrity and function in the presence of APOE4
16. C90RF72 repeat expansions in mice cause TDP-43 pathology, neuronal loss, and behavioral deficits
17. APOE genotype modifies benefits of calorie restriction against aging.
18. APOE2 Exacerbates TDP ‐43 Related Toxicity in the Absence of Alzheimer Pathology
19. Severe amygdala dysfunction in a MAPT transgenic mouse model of frontotemporal dementia
20. Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy
21. APOE ε2 is associated with increased tau pathology in primary tauopathy
22. Loss of Tmem106b is unable to ameliorate frontotemporal dementia-like phenotypes in an AAV mouse model of C9ORF72-repeat induced toxicity
23. Two FTD-ALS genes converge on the endosomal pathway to induce TDP-43 pathology and degeneration
24. Cell-autonomous effects of APOE4in restricting microglial response in brain homeostasis and Alzheimer’s disease
25. Plasma PolyQ-ATXN3 Levels Associate With Cerebellar Degeneration and Behavioral Abnormalities in a New AAV-Based SCA3 Mouse Model
26. APOE3-Jacksonville (V236E) variant reduces self-aggregation and risk of dementia: Implications for therapeutic strategy
27. Tau deposition drives neuropathological, inflammatory and behavioral abnormalities independently of neuronal loss in a novel mouse model
28. Vascular ApoE4 Impairs Behavior by Modulating Gliovascular Function
29. APOE3 -Jacksonville (V236E) variant reduces self-aggregation and risk of dementia
30. Hexanucleotide Repeat Expansions in c9FTD/ALS and SCA36 Confer Selective Patterns of Neurodegeneration In Vivo
31. Two FTD-ALS genes converge on the endosomal pathway to induce TDP-43 pathology and degeneration.
32. Loss of Tmem106b leads to cerebellum Purkinje cell death and motor deficits
33. Loss of Tmem106b leads to cerebellum Purkinje cell death and motor deficits
34. APOE2 is associated with longevity independent of Alzheimer’s disease
35. Author response: APOE2 is associated with longevity independent of Alzheimer’s disease
36. APOE2promotes longevity independent of Alzheimer’s disease
37. Additional file 5 of Astrocyte-derived clusterin suppresses amyloid formation in vivo
38. Additional file 6 of Astrocyte-derived clusterin suppresses amyloid formation in vivo
39. Additional file 1 of Astrocyte-derived clusterin suppresses amyloid formation in vivo
40. Additional file 2 of Astrocyte-derived clusterin suppresses amyloid formation in vivo
41. Additional file 7 of Astrocyte-derived clusterin suppresses amyloid formation in vivo
42. Additional file 3 of Astrocyte-derived clusterin suppresses amyloid formation in vivo
43. Additional file 1 of Clusterin ameliorates tau pathology in vivo by inhibiting fibril formation
44. Additional file 4 of Astrocyte-derived clusterin suppresses amyloid formation in vivo
45. APOE2 is associated with longevity independent of Alzheimer’s disease
46. Additional file 1: of Enhanced phosphorylation of T153 in soluble tau is a defining biochemical feature of the A152T tau risk variant
47. APOE4 exacerbates α-synuclein pathology and related toxicity independent of amyloid
48. TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics
49. Additional file 1: of Loss of Tmem106b is unable to ameliorate frontotemporal dementia-like phenotypes in an AAV mouse model of C9ORF72-repeat induced toxicity
50. Vascular apoE4 Impairs Brain Cognition by Modulating Glio-Vascular Functions
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