124 results on '"Konka M"'
Search Results
2. Right ventricular damage in young athletes with arrhythmias.: 281
- Author
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Fejfer, K, Biernacka, E K, Kolodziej, M K, Hoffman, P, Baranowski, R, Konka, M, and Malek, L
- Published
- 2013
3. Isolated ventricular non-compaction in a patient initially diagnosed with arrhythmogenic right ventricular cardiomyopathy
- Author
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Wozniak, O, Konka, M, and Wlodarska, E K
- Published
- 2008
- Full Text
- View/download PDF
4. P6103Atrial septal defect perimeter as a valuable alternative to balloon-sizing technique in the interventional approach
- Author
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Henzel, J., primary, Konka, M., additional, Wojcik, A., additional, Rudzinski, P.N., additional, Pracon, R., additional, Dzielinska, Z., additional, Hoffman, P., additional, and Demkow, M., additional
- Published
- 2017
- Full Text
- View/download PDF
5. 1934One extra plug to completely seal the left atrial appendage - procedure guided by 3D-printed model of the heart
- Author
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Pracon, R., primary, Grygoruk, R., additional, Kaczmarska, E., additional, Kepka, C., additional, Konka, M., additional, Dzielinska, Z., additional, Witkowski, A., additional, and Demkow, M., additional
- Published
- 2017
- Full Text
- View/download PDF
6. Poster session 2: Thursday 4 December 2014, 08:30-12:30Location: Poster area
- Author
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Domingos, J, Augustine, D, Leeson, P, Noble, J, Doan, HL, Boubrit, L, Cheikh-Khalifa, R, Laveau, F, Djebbar, M, Pousset, F, Isnard, R, Hammoudi, N, Lisi, M, Cameli, M, Di Tommaso, C, Curci, V, Reccia, R, Maccherini, M, Henein, MY, Mondillo, S, Leitman, M, Vered, Z, Rashid, H, Yalcin, MU, Gurses, KM, Kocyigit, D, Evranos, B, Yorgun, H, Sahiner, L, Kaya, B, Aytemir, K, Ozer, N, Bertella, E, Petulla', M, Baggiano, A, Mushtaq, S, Russo, E, Gripari, P, Innocenti, E, Andreini, D, Tondo, C, Pontone, G, Necas, J, Kovalova, S, Hristova, K, Shiue, I, Bogdanva, V, Teixido Tura, G, Sanchez, V, Rodriguez-Palomares, J, Gutierrez, L, Gonzalez-Alujas, T, Garcia-Dorado, D, Forteza, A, Evangelista, A, Timoteo, AT, Aguiar Rosa, S, Cruz Ferreira, R, Campbell, R, Carrick, D, Mccombe, C, Tzemos, N, Berry, C, Sonecki, P, Noda, M, Setoguchi, M, Ikenouchi, T, Nakamura, T, Yamamoto, Y, Murakami, T, Katou, Y, Usui, M, Ichikawa, K, Isobe, M, Kwon, B, Roh, J, Kim, H, Ihm, S, Barron, AJ, Francis, D, Mayet, J, Wensel, R, Kosiuk, J, Dinov, B, Bollmann, A, Hindricks, G, Breithardt, O, Rio, P, Moura Branco, L, Galrinho, A, Cacela, D, Pinto Teixeira, P, Afonso Nogueira, M, Pereira-Da-Silva, T, Abreu, J, Teresa Timoteo, A, Pavlyukova, E, Tereshenkova, E, Karpov, R, Piatkowski, R, Kochanowski, J, Opolski, G, Barbier, P, Mirea, O, Guglielmo, M, Savioli, G, Cefalu, C, Pudil, R, Horakova, L, Rozloznik, M, Balestra, C, Rimbas, R, Enescu, O, Calin, S, Vinereanu, D, Karsenty, C, Hascoet, S, Hadeed, K, Semet, F, Dulac, Y, Alacoque, X, Leobon, B, Acar, P, Dharma, S, Sukmawan, R, Soesanto, A, Vebiona, K, Firdaus, I, Danny, S, Driessen, MM, Sieswerda, G, Post, M, Snijder, R, Van Dijk, A, Leiner, T, Meijboom, F, Chrysohoou, C, Tsitsinakis, G, Tsiachris, D, Aggelis, A, Herouvim, E, Vogiatzis, I, Pitsavos, C, Koulouris, G, Stefanadis, C, Erdei, T, Edwards, J, Braim, D, Yousef, Z, Fraser, A, Avenatti, E, Magnino, C, Omede', P, Presutti, D, Moretti, C, Iannaccone, A, Ravera, A, Gaita, F, Milan, A, Veglio, F, Scali, M, Simioniuc, A, Fusini, L, Dini, F, Okura, H, Murata, E, Kataoka, T, Mikaelpoor, A, Ojaghi Haghighi, S, Alizadeasl, A, Sharifi-Zarchi, A, Zaroui, A, Ben Halima, M, Mourali, M, Mechmeche, R, Rodriguez Palomares, JF, Maldonado, G, Garcia, G, Otaegui, I, Garcia Del Blanco, B, Teixido, G, Gonzalez Alujas, M, Garcia Dorado, D, Godinho, AR, Correia, A, Rangel, I, Rocha, A, Rodrigues, J, Araujo, V, Almeida, P, Macedo, F, Maciel, M, Rekik, B, Mghaieth, F, Aloui, H, Boudiche, S, Jomaa, M, Ayari, J, Tabebi, N, Farhati, A, Mourali, S, Dekleva, M, Markovic-Nikolic, N, Zivkovic, M, Stankovic, A, Boljevic, D, Korac, N, Beleslin, B, Arandjelovic, A, Ostojic, M, Galli, E, Guirette, Y, Auffret, V, Daudin, M, Fournet, M, Mabo, P, Donal, E, Chin, CW, Luo, E, Hwan, J, White, A, Newby, D, Dweck, M, Carstensen, HG, Larsen, LH, Hassager, C, Kofoed, KF, Jensen, JS, Mogelvang, R, Kowalczyk, M, Debska, M, Kolesnik, A, Dangel, J, Kawalec, W, Migliore, R, Adaniya, M, Barranco, M, Miramont, G, Gonzalez, S, Tamagusuku, H, Davidsen, ES, Kuiper, KK, Matre, K, Gerdts, E, Igual Munoz, B, Maceira Gonzalez, A, Erdociain Perales, M, Estornell Erill, J, Valera Martinez, F, Miro Palau, V, Piquer Gil, M, Sepulveda Sanchez, P, Cervera Zamora, A, Montero Argudo, A, Placido, R, Silva Marques, J, Magalhaes, A, Guimaraes, T, Nobre E Menezes, M, Goncalves, S, Ramalho, A, Robalo Martins, S, Almeida, A, Nunes Diogo, A, Abid, L, Ben Kahla, S, Charfeddine, S, Abid, D, Kammoun, S, Tounsi, A, Hammami, R, Triki, F, Akrout, M, Mallek, S, Hentati, M, Sirbu, CF, Berrebi, A, Huber, A, Folliguet, T, Yang, LT, Shih, J, Liu, Y, Li, Y, Tsai, L, Luo, C, Tsai, W, Babukov, R, Bartosh, F, Bazilev, V, Muraru, D, Cavalli, G, Addetia, K, Miglioranza, M, Veronesi, F, Mihaila, S, Tadic, M, Cucchini, U, Badano, L, Lang, R, Miyazaki, S, Slavich, M, Miyazaki, T, Figini, F, Lativ, A, Chieffo, A, Montrfano, M, Alfieri, O, Colombo, A, Agricola, E, Liu, D, Hu, K, Herrmann, S, Stoerk, S, Kramer, B, Ertl, G, Bijnens, B, Weidemann, F, Brand, M, Butz, T, Tzikas, S, Van Bracht, M, Roeing, J, Wennemann, R, Christ, M, Grett, M, Trappe, HJ, Scherzer, S, Geroldinger, A, Krenn, L, Roth, C, Gangl, C, Maurer, G, Rosenhek, R, Neunteufl, T, Binder, T, Bergler-Klein, J, Martins, E, Pinho, T, Leite, S, Azevedo, O, Belo, A, Campelo, M, Amorim, S, Rocha-Goncalves, F, Goncalves, L, Silva-Cardoso, J, Ahn, H, Kim, K, Jeon, H, Youn, H, Haland, T, Saberniak, J, Leren, I, Edvardsen, T, Haugaa, K, Ziolkowska, L, Boruc, A, Turska-Kmiec, A, Zubrzycka, M, Monivas Palomero, V, Mingo Santos, S, Goirigolzarri Artaza, J, Rodriguez Gonzalez, E, Rivero Arribas, B, Castro Urda, V, Dominguez Rodriguez, F, Mitroi, C, Gracia Lunar, I, Fernadez Lozano, I, Palecek, T, Masek, M, Kuchynka, P, Fikrle, M, Spicka, I, Rysava, R, Linhart, A, Hasselberg, N, Borgquist, R, Platonov, P, Ancona, R, Comenale Pinto, S, Caso, P, Coopola, M, Arenga, F, Rapisarda, O, D'onofrio, A, Sellitto, V, Calabro, R, Rosca, M, Popescu, B, Calin, A, Mateescu, A, Beladan, C, Jalba, M, Rusu, E, Zilisteanu, D, Ginghina, C, Pressman, G, Cepeda-Valery, B, Romero-Corral, A, Moldovan, R, Saenz, A, Orban, M, Samuel, S, Fijalkowski, M, Fijalkowska, M, Gilis-Siek, N, Blaut, K, Galaska, R, Sworczak, K, Gruchala, M, Nowak, R, Ikonomidis, I, Triantafyllidi, H, Trivilou, P, Tzortzis, S, Papadopoulos, C, Pavlidis, G, Paraskevaidis, I, Lekakis, J, Padiyath, A, Li, L, Xiao, Y, Danford, D, Kutty, S, Kaymaz, C, Aktemur, T, Poci, N, Ozturk, S, Akbal, O, Yilmaz, F, Tokgoz Demircan, H, Kirca, N, Tanboga, I, Ozdemir, N, Greiner, S, Jud, A, Aurich, M, Hess, A, Hilbel, T, Hardt, S, Katus, H, D'ascenzi, F, Alvino, F, Focardi, M, Solari, M, Bonifazi, M, Konopka, M, Krol, W, Klusiewicz, A, Burkhard, K, Chwalbinska, J, Pokrywka, A, Dluzniewski, M, Braksator, W, King, GJ, Coen, K, Gannon, S, Fahy, N, Kindler, H, Clarke, J, Iliuta, L, Rac-Albu, M, Cortez-Dias, N, Francisco, A, Silva, G, Kyu, K, Kong, W, Songco, G, Galupo, M, Castro, M, Shin Hnin, W, Ronald Lee, C, Poh, K, Milazzo, V, Di Stefano, C, Tosello, F, Leone, D, Sabia, L, Sobrero, G, Maule, S, Jamiel, AM, Ahmed, AM, Farah, I, Al-Mallah, MH, Petroni, R, Magnano, R, Bencivenga, S, Di Mauro, M, Petroni, S, Altorio, S, Romano, S, Penco, M, Kumor, M, Lipczynska, M, Klisiewicz, A, Wojcik, A, Konka, M, Kozuch, K, Szymanski, P, Hoffman, P, Rimbas, M, Reynaud, A, Lund, L, Persson, H, Hage, C, Oger, E, Linde, C, Daubert, J, Maria Oliveira Lima, M, Costa, H, Gomes Da Silva, M, Noman Alencar, M, Carmo Pereira Nunes, M, Costa Rocha, M, Siala, A, Ozawa, K, Funabashi, N, Takaoka, H, Kobayashi, Y, Matsumura, Y, Wada, M, Hirakawa, D, Yasuoka, Y, Morimoto, N, Takeuchi, H, Kitaoka, H, Sugiura, T, Lakkas, L, Naka, K, Ntounousi, E, Gkirdis, I, Koutlas, V, Bechlioulis, A, Pappas, K, Katsouras, C, Siamopoulos, K, Michalis, L, Evangelou, D, Kalaitzidis, R, Tzeltzes, G, Nakas, G, Generati, G, Bandera, F, Pellegrino, M, Labate, V, Alfonzetti, E, Guazzi, M, Zagatina, A, Zhuravskaya, N, Al-Mallah, M, Alsaileek, A, Qureshi, W, Peyre, M, Amadieu, R, Yamanaka, Y, Sotomi, Y, Iwakura, K, Inoue, K, Toyoshima, Y, Tanaka, K, Oka, T, Tanaka, N, Orihara, Y, Fujii, K, Soulat-Dufour, L, Lang, S, Boyer-Chatenet, L, Van Der Vynckt, C, Ederhy, S, Adavane, S, Haddour, N, Boccara, F, Cohen, A, Huitema, M, Boerman, S, Vorselaars, V, Grutters, J, Gopal, AS, Saha, S, Toole, R, Kiotsekoglou, A, Cao, J, Reichek, N, Meyer, CG, Altiok, E, Al Ateah, G, Lehrke, M, Becker, M, Lotfi, S, Autschbach, R, Marx, N, Hoffmann, R, Frick, M, Nemes, A, Sepp, R, Kalapos, A, Domsik, P, Forster, T, Caro Codon, J, Blazquez Bermejo, Z, Lopez Fernandez, T, Valbuena Lopez, SC, Iniesta Manjavacas, AM, De Torres Alba, F, Dominguez Melcon, F, Pena Conde, L, Moreno Yanguela, M, Lopez-Sendon, JL, Lengyel, C, Orosz, A, Varkonyi, T, Rendon, J, Saldarriaga, CI, Duarte, N, Foldeak, D, Borbenyi, Z, Hamdy, A, Fereig, H, Nabih, M, Abdel-Aziz, A, Ali, A, Broyd, C, Wielandts, JY, De Buck, S, Michielsen, K, Louw, R, Garweg, C, Nuyts, J, Ector, J, Maes, F, Heidbuchel, H, Gillis, K, Bala, G, Tierens, S, Cosyns, B, Maurovich-Horvat, P, Horvath, T, Jermendy, A, Celeng, C, Panajotu, A, Bartykowszki, A, Karolyi, M, Tarnoki, A, Jermendy, G, and Merkely, B
- Subjects
medicine.medical_specialty ,biology ,Early Repolarization Pattern ,business.industry ,Athletes ,Physical therapy ,medicine ,Radiology, Nuclear Medicine and imaging ,General Medicine ,Cardiology and Cardiovascular Medicine ,business ,biology.organism_classification - Published
- 2014
7. Isolated ventricular non-compaction in a patient initially diagnosed with arrhythmogenic right ventricular cardiomyopathy
- Author
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Wozniak, O, primary, Konka, M, additional, and Wlodarska, E K, additional
- Published
- 2009
- Full Text
- View/download PDF
8. Long-term exercise capacity of patients with hypertrophic cardiomyopathy treated with percutaneous alcohol septal myocardial ablation
- Author
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MALEK, L, primary, CHOJNOWSKA, L, additional, KLOPOTOWSKI, M, additional, DEMKOW, M, additional, WITKOWSKI, A, additional, KUSMIERCZYK, B, additional, PIOTROWICZ, E, additional, KONKA, M, additional, DABROWSKI, M, additional, and RUZYLLO, W, additional
- Published
- 2008
- Full Text
- View/download PDF
9. Aortic regurgitation and unusual diastolic mitral regurgitation
- Author
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Konka, M., primary, Kusmierczyk-Droszcz, B., additional, Wozniak, O., additional, and Hoffman, P., additional
- Published
- 2008
- Full Text
- View/download PDF
10. 446 Double orifice mitral valve. Clinical and echocardiographic features
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WOJCIK, A, primary, KLISIEWICZ, A, additional, KONKA, M, additional, SZYMANSKI, P, additional, MICHALEK, P, additional, LUSAWA, P, additional, ROZANSKI, J, additional, and HOFFMAN, P, additional
- Published
- 2006
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11. 372 Long term follow-up of patients with arrhythmogenic right ventricular cardiomyopathy and ventricular tachycardia treated by catheter ablation
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Wlodarska, E.K., primary, Szumowski, L., additional, Wozniak, O., additional, Sanders, P., additional, Konka, M., additional, Jais, R., additional, Hocini, M., additional, Hoffman, R., additional, Haissaguerre, M., additional, and Walczak, F., additional
- Published
- 2005
- Full Text
- View/download PDF
12. LEPTIN PLASMA CONCENTRATION IN RELATION TO BLOOD PRESSURE RHYTHM, HEART RATE AND LEFT VENTRICULAR MASS INDEX IN OBESE PATIENTS WITH ESSENTIAL HYPERTENSION
- Author
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Pucilowska, B., primary, Paschalis-Purtak, K., additional, Hoffman, P., additional, Janas, J., additional, Makowiecka-Ciesla, M., additional, Kabat, M., additional, Prejbisz, A., additional, Konka, M., additional, and Januszewicz, A., additional
- Published
- 2004
- Full Text
- View/download PDF
13. 928 Rapid assessment of valvular regurgitation with ultrasound stethoscope - a side by side comparison with standard echocardiography
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SZYMANSKI, P, primary, KLISIEWICZ, A, additional, KRASZEWSKI, K, additional, KONKA, M, additional, and HOFFMAN, P, additional
- Published
- 2003
- Full Text
- View/download PDF
14. 358 Ventricular septal defect - not only congenital heart disease
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KONKA, M, primary and HOFFMAN, P, additional
- Published
- 2003
- Full Text
- View/download PDF
15. 785 How to predict development of severe mitral regurgitation after percutaneous mitral commissurotomy?
- Author
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KONKA, M, primary, HOFFMAN, P, additional, CHMIELAK, Z, additional, and RUZYLLO, W, additional
- Published
- 2003
- Full Text
- View/download PDF
16. Familial form of arrhythmogenic right ventricular cardiomyopathy,Rodzinna postać arytmogennej dysplazji prawej komory
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Włodarska, E. K., Konka, M., Kȩpski, R., Zaleska, T., Płoski, R., Ruzyłło, W., Marianna Janion, Jaworska, K., Rydlewska-Sadowska, W., Hoffman, P., and Kornacewicz-Jach, Z.
17. Development, implementation and validation of ECHO-TeleDICOM - Polish system for interactive teleconsultation of echocardiography studies,Opracowanie, wdroz•enie i ocena działania polskiego systemu do interaktywnych telekonsultacji badań echokardiograficznych ECHO-TeleDICOM
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Gackowski, A., Nowak, M., Czekierda, Ł., Chrustowicz, A., Cała, J., Masternak, T., Koprowski, A., Mokrzycki, K., Sonecki, P., Podolec, P., Pasowicz, M., Konka, M., Piotr Szymański, Kocik, P., Zabówka, M., Młotek, M., Piwowarska, W., and Zieliński, K.
18. Stroke in young diver with patent foramen ovale,Udar mózgu u młodego nurka z drożnym otworem owalnym
- Author
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Hrynkiewicz-Szymańska, A., Kuch, M., Demkow, M., Barczewska, M., Wojciech Braksator, Konka, M., and Dłuzniewski, M.
19. Arrhythmogenic right ventricular cardiomyopathy, Brugada syndrome and multilevel cardiac conduction disease,Arytmogenna kardiomiopatia prawej komory i zespół Brugadów u chorego z wielopoziomowym uszkodzeniem układu bodźcoprzewodzacego serca
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Włodarska, E., Wójcik, A., Walczak, F., Przybylski, A., Konka, M., Edward Koźluk, Kepski, R., Rydlewska-Sadowska, W., Szwed, H., and Hoffman, P.
20. Role of electrophysiologic properties of the A-V node and His-Purkinje system in triggering inappropriate ICD discharges in a patient with arrhythmogenic right ventricular dysplasia. Effective treatment with RF ablation,Wpływ właściwości wezła przedsionkowo-komorowego i układu Hisa-Purkinjego na wystepowanie niewłaściwych wyładowań ICD u pacjenta z arytmogenna kardiomiopatia prawej komory - leczenia ablacja
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Włodarska, E. K., Szumowski, L., Andrzej Przybylski, Konka, M., Walczak, E., Zaleska, T., Kepski, R., Urbanek, P., Derejko, P., Ruzyłło, W., Szwed, H., Hoffman, P., and Walczak, F.
21. Poster session 2: Thursday 4 December 2014, 08:30-12:30 * Location: Poster area
- Author
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Domingos, JS, Augustine, DX, Leeson, P, Noble, JA, Doan, H-L, Boubrit, L, Cheikh-Khalifa, R, Laveau, F, Djebbar, M, Pousset, F, Isnard, R, Hammoudi, N, Lisi, M, Cameli, M, Di Tommaso, C, Curci, V, Reccia, R, Maccherini, M, Henein, M Y, Mondillo, S, Leitman, M, Vered, Z, Rashid, H, Yalcin, M U, Gurses, K M, Kocyigit, D, Evranos, B, Yorgun, H, Sahiner, L, Kaya, B, Aytemir, K, Ozer, N, Bertella, E, Petulla', M, Baggiano, A, Mushtaq, S, Russo, E, Gripari, P, Innocenti, E, Andreini, D, Tondo, C, Pontone, G, Necas, J, Kovalova, S, Hristova, K, Shiue, I, Bogdanva, V, Teixido Tura, G, Sanchez, V, Rodriguez-Palomares, J, Gutierrez, L, Gonzalez-Alujas, T, Garcia-Dorado, D, Forteza, A, Evangelista, A, Timoteo, A T, Aguiar Rosa, S, Cruz Ferreira, R, Campbell, R, Carrick, D, Mccombe, C, Tzemos, N, Berry, C, Sonecki, P, Noda, M, Setoguchi, M, Ikenouchi, T, Nakamura, T, Yamamoto, Y, Murakami, T, Katou, Y, Usui, M, Ichikawa, K, Isobe, M, Kwon, BJ, Roh, JW, Kim, HY, Ihm, SH, Barron, A J, Francis, DP, Mayet, J, Wensel, R, Kosiuk, J, Dinov, B, Bollmann, A, Hindricks, G, Breithardt, OA, Rio, P, Moura Branco, L, Galrinho, A, Cacela, D, Pinto Teixeira, P, Afonso Nogueira, M, Pereira-Da-Silva, T, Abreu, J, Teresa Timoteo, A, Cruz Ferreira, R, Pavlyukova, EN, Tereshenkova, EK, Karpov, RS, Piatkowski, R, Kochanowski, J, Opolski, G, Barbier, P, Mirea, O, Guglielmo, M, Savioli, G, Cefalu, C, Pudil, R, Horakova, L, Rozloznik, M, Balestra, C, P37/03, PRVOUK, Rimbas, RC, Enescu, OA, Calin, S, Vinereanu, D, POSDRU/159/1.5/S/141531, Grant, Karsenty, C, Hascoet, S, Hadeed, K, Semet, F, Dulac, Y, Alacoque, X, Leobon, B, Acar, P, Dharma, S, Sukmawan, R, Soesanto, AM, Vebiona, KPP, Firdaus, I, Danny, SS, Driessen, M M P, Sieswerda, GTJ, Post, MC, Snijder, RJ, Van Dijk, APJ, Leiner, T, Meijboom, FJ, Chrysohoou, C, Tsitsinakis, G, Tsiachris, D, Aggelis, A, Herouvim, E, Vogiatzis, I, Pitsavos, C, Koulouris, G, Stefanadis, C, Erdei, T, Edwards, J, Braim, D, Yousef, Z, Fraser, AG, Cardiff, Investigators, MEDIA, Avenatti, E, Magnino, C, Omede', P, Presutti, D, Moretti, C, Iannaccone, A, Ravera, A, Gaita, F, Milan, A, Veglio, F, Barbier, P, Scali, MC, Simioniuc, A, Guglielmo, M, Savioli, G, Cefalu, C, Mirea, O, Fusini, L, Dini, F, Okura, H, Murata, E, Kataoka, T, Mikaelpoor, A, Ojaghi Haghighi, SH, Ojaghi Haghighi, SZ, Alizadeasl, A, Sharifi-Zarchi, A, Zaroui, A, Ben Halima, M, Mourali, MS, Mechmeche, R, Rodriguez Palomares, J F, Gutierrez, LG, Maldonado, GM, Garcia, GG, Otaegui, IO, Garcia Del Blanco, BGB, Teixido, GT, Gonzalez Alujas, MTGA, Evangelista, AE, Garcia Dorado, DGD, Godinho, A R, Correia, AS, Rangel, I, Rocha, A, Rodrigues, J, Araujo, V, Almeida, PB, Macedo, F, Maciel, MJ, Rekik, B, Mghaieth, F, Aloui, H, Boudiche, S, Jomaa, M, Ayari, J, Tabebi, N, Farhati, A, Mourali, S, Dekleva, M, Markovic-Nikolic, N, Zivkovic, M, Stankovic, A, Boljevic, D, Korac, N, Beleslin, B, Arandjelovic, A, Ostojic, M, Galli, E, Guirette, Y, Auffret, V, Daudin, M, Fournet, M, Mabo, P, Donal, E, Chin, C W L, Luo, E, Hwan, J, White, A, Newby, D, Dweck, M, Carstensen, H G, Larsen, L H, Hassager, C, Kofoed, K F, Jensen, J S, Mogelvang, R, Kowalczyk, M, Debska, M, Kolesnik, A, Dangel, J, Kawalec, W, Migliore, RA, Adaniya, ME, Barranco, MA, Miramont, G, Gonzalez, S, Tamagusuku, H, Davidsen, E S, Kuiper, K K J, Matre, K, Gerdts, E, Igual Munoz, B, Maceira Gonzalez, AMG, Erdociain Perales, MEP, Estornell Erill, JEE, Valera Martinez, FVM, Miro Palau, VMP, Piquer Gil, MPG, Sepulveda Sanchez, PSS, Cervera Zamora, ACZ, Montero Argudo, AMA, Placido, R, Silva Marques, J, Magalhaes, A, Guimaraes, T, Nobre E Menezes, M, Goncalves, S, Ramalho, A, Robalo Martins, S, Almeida, AG, Nunes Diogo, A, Abid, L, Ben Kahla, S, Charfeddine, S, Abid, D, Kammoun, S, Tounsi, A, Abid, LEILA, Abid, DORRA, Charfeddine, SALMA, Hammami, RANIA, Triki, FETEN, Akrout, MALEK, Mallek, SOUAD, Hentati, MOURAD, Kammoun, SAMIR, Sirbu, C F, Berrebi, A, Huber, A, Folliguet, T, Yang, L-T, Shih, JY, Liu, YW, Li, YH, Tsai, LM, Luo, CY, Tsai, WC, Babukov, R, Bartosh, F, Bazilev, V, Muraru, D, Cavalli, G, Addetia, K, Miglioranza, MH, Veronesi, F, Mihaila, S, Tadic, M, Cucchini, U, Badano, L, Lang, RM, Miyazaki, S, Slavich, M, Miyazaki, T, Figini, F, Lativ, A, Chieffo, A, Montrfano, M, Alfieri, O, Colombo, A, Agricola, E, Liu, D, Hu, K, Herrmann, S, Stoerk, S, Kramer, B, Ertl, G, Bijnens, B, Weidemann, F, Brand, M, Butz, T, Tzikas, S, Van Bracht, M, Roeing, J, Wennemann, R, Christ, M, Grett, M, Trappe, H-J, Scherzer, S, Geroldinger, AG, Krenn, L, Roth, C, Gangl, C, Maurer, G, Rosenhek, R, Neunteufl, T, Binder, T, Bergler-Klein, J, Martins, E, Pinho, T, Leite, S, Azevedo, O, Belo, A, Campelo, M, Amorim, S, Rocha-Goncalves, F, Goncalves, L, Silva-Cardoso, J, Ahn, HS, Kim, KT, Jeon, HK, Youn, HJ, Haland, T, Saberniak, J, Leren, IS, Edvardsen, T, Haugaa, KH, Ziolkowska, L, Boruc, A, Kowalczyk, M, Turska-Kmiec, A, Zubrzycka, M, Kawalec, W, Monivas Palomero, V, Mingo Santos, S, Goirigolzarri Artaza, J, Rodriguez Gonzalez, E, Rivero Arribas, B, Castro Urda, V, Dominguez Rodriguez, F, Mitroi, C, Gracia Lunar, I, Fernadez Lozano, I, Palecek, T, Masek, M, Kuchynka, P, Fikrle, M, Spicka, I, Rysava, R, Linhart, A, Saberniak, J, Hasselberg, NE, Leren, IS, Haland, T, Borgquist, R, Platonov, PG, Edvardsen, T, Haugaa, KH, Ancona, R, Comenale Pinto, S, Caso, P, Coopola, MG, Arenga, F, Rapisarda, O, D'onofrio, A, Sellitto, V, Calabro, R, Rosca, M, Popescu, BA, Calin, A, Mateescu, A, Beladan, CC, Jalba, M, Rusu, E, Zilisteanu, D, Ginghina, C, Pressman, G, Cepeda-Valery, B, Romero-Corral, A, Moldovan, R, Saenz, A, Orban, M, Samuel, SP, Fijalkowski, M, Fijalkowska, M, Gilis-Siek, N, Blaut, K, Galaska, R, Sworczak, K, Gruchala, M, Fijalkowski, M, Nowak, R, Gilis-Siek, N, Fijalkowska, M, Galaska, R, Gruchala, M, Ikonomidis, I, Triantafyllidi, H, Trivilou, P, Tzortzis, S, Papadopoulos, C, Pavlidis, G, Paraskevaidis, I, Lekakis, J, Padiyath, A, Li, L, Xiao, Y, Danford, DA, Kutty, S, Kaymaz, C, Aktemur, T, Poci, N, Ozturk, S, Akbal, O, Yilmaz, F, Tokgoz Demircan, HC, Kirca, N, Tanboga, IH, Ozdemir, N, Investigators, EUPHRATES, Greiner, S, Jud, A, Aurich, M, Hess, A, Hilbel, T, Hardt, S, Katus, HA, D'ascenzi, F, Cameli, M, Alvino, F, Lisi, M, Focardi, M, Solari, M, Bonifazi, M, Mondillo, S, Konopka, M, Krol, W, Klusiewicz, A, Burkhard, K, Chwalbinska, J, Pokrywka, A, Dluzniewski, M, Braksator, W, King, G J, Coen, K, Gannon, S, Fahy, N, Kindler, H, Clarke, J, Iliuta, L, Rac-Albu, M, Placido, R, Robalo Martins, S, Guimaraes, T, Nobre E Menezes, M, Cortez-Dias, N, Francisco, A, Silva, G, Goncalves, S, Almeida, AG, Nunes Diogo, A, Kyu, K, Kong, WKF, Songco, GG, Galupo, MJ, Castro, MD, Shin Hnin, W, Ronald Lee, CH, Poh, KK, Milazzo, V, Di Stefano, C, Tosello, F, Leone, D, Ravera, A, Sabia, L, Sobrero, G, Maule, S, Veglio, F, Milan, A, Jamiel, A M, Ahmed, A M, Farah, I, Al-Mallah, M H, Petroni, R, Magnano, R, Bencivenga, S, Di Mauro, M, Petroni, S, Altorio, SF, Romano, S, Penco, M, Kumor, M, Lipczynska, M, Klisiewicz, A, Wojcik, A, Konka, M, Kozuch, K, Szymanski, P, Hoffman, P, Rimbas, RC, Rimbas, M, Enescu, OA, Mihaila, S, Calin, S, Vinereanu, D, 112/2011, Grant CNCSIS, 159/1.5/S/141531, Grant POSDRU, Donal, E, Reynaud, A, Lund, LH, Persson, H, Hage, C, Oger, E, Linde, C, Daubert, JC, investigators, KaRen, Maria Oliveira Lima, M, Costa, H, Gomes Da Silva, M, Noman Alencar, MC, Carmo Pereira Nunes, M, Costa Rocha, MO, Abid, L, Charfeddine, S, Ben Kahla, S, Abid, D, Siala, A, Hentati, M, Kammoun, S, Kovalova, S, Necas, J, Ozawa, K, Funabashi, N, Takaoka, H, Kobayashi, Y, Matsumura, Y, Wada, M, Hirakawa, D, Yasuoka, Y, Morimoto, N, Takeuchi, H, Kitaoka, H, Sugiura, T, Lakkas, L, Naka, KK, Ntounousi, E, Gkirdis, I, Koutlas, V, Bechlioulis, A, Pappas, K, Katsouras, CS, Siamopoulos, K, Michalis, LK, Naka, KK, Evangelou, D, Kalaitzidis, R, Bechlioulis, A, Lakkas, L, Gkirdis, I, Tzeltzes, G, Nakas, G, Katsouras, CS, Michalis, LK, Generati, G, Bandera, F, Pellegrino, M, Labate, V, Alfonzetti, E, Guazzi, M, Zagatina, A, Zhuravskaya, N, Al-Mallah, M, Alsaileek, A, Qureshi, W, Karsenty, C, Hascoet, S, Peyre, M, Hadeed, K, Alacoque, X, Amadieu, R, Leobon, B, Dulac, Y, Acar, P, Yamanaka, Y, Sotomi, Y, Iwakura, K, Inoue, K, Toyoshima, Y, Tanaka, K, Oka, T, Tanaka, N, Orihara, Y, Fujii, K, Soulat-Dufour, L, Lang, S, Boyer-Chatenet, L, Van Der Vynckt, C, Ederhy, S, Adavane, S, Haddour, N, Boccara, F, Cohen, A, Huitema, MP, Boerman, S, Vorselaars, VMM, Grutters, JC, Post, MC, Gopal, A S, Saha, SK, Toole, RS, Kiotsekoglou, A, Cao, JJ, Reichek, N, Meyer, C G, Altiok, E, Al Ateah, G, Lehrke, M, Becker, M, Lotfi, S, Autschbach, R, Marx, N, Hoffmann, R, Frick, M, Nemes, A, Sepp, R, Kalapos, A, Domsik, P, Forster, T, Caro Codon, J, Blazquez Bermejo, Z, Lopez Fernandez, T, Valbuena Lopez, S C, Iniesta Manjavacas, A M, De Torres Alba, F, Dominguez Melcon, F, Pena Conde, L, Moreno Yanguela, M, Lopez-Sendon, J L, Nemes, A, Lengyel, C, Domsik, P, Kalapos, A, Orosz, A, Varkonyi, TT, Forster, T, Rendon, J, Saldarriaga, C I, Duarte, N, Nemes, A, Domsik, P, Kalapos, A, Forster, T, Nemes, A, Domsik, P, Kalapos, A, Sepp, R, Foldeak, D, Borbenyi, Z, Forster, T, Hamdy, AM, Fereig, HM, Nabih, MA, Abdel-Aziz, A, Ali, AA, Broyd, CJ, Wielandts, J-Y, De Buck, S, Michielsen, K, Louw, R, Garweg, C, Nuyts, J, Ector, J, Maes, F, Heidbuchel, H, Gillis, K, Bala, G, Tierens, S, Cosyns, B, Maurovich-Horvat, P, Horvath, T, Jermendy, A, Celeng, C, Panajotu, A, Bartykowszki, A, Karolyi, M, Tarnoki, AD, Jermendy, G, and Merkely, B
- Abstract
Purpose: 3D echocardiography (3DE) enables fast 3D acquisition but subsequent manual navigation to find 2D diagnostic planes can be time consuming. We have developed and validated an automated machine learning-based technique to find apical 2-, 3- and 4-chamber (A2C, A3C, A4C) views that enables fast volume navigation and analysis. Methods: 3DE volumes were acquired (Philips iE33: X3-1 and X5-1 probes) from 30 healthy volunteers and 36 clinical patients with suspected valve disease and coronary heart disease. 66 end diastolic volumes were used to assess the accuracy of apical standard view finding by our method against manual plane finding. To do this, dedicated software was developed with a machine learning approach and a 3-fold cross validation of results was performed. Results: Automatic A4C view detection was possible in 60/66 (91%) of volumes; detection failures were due to suboptimal myocardium wall integrity or lack of right ventricle in the scan. A2C and A3C views were extracted from the A4C view using the known geometrical relationships between apical standard views (A2C to A3C: 30°~40° and A2C to A4C: 90° of rotation over the left ventricle long axis, as shown in the Figure). In average, our method accurately found the heart apex and mitral valve centre with a 7.1 ± 5.7 mm and 7.2 ± 5.3 mm error, respectively. Conclusions: In order to automate clinical workflow, we have developed a new and fully automatic machine learning strategy for apical standard view finding which performed well (91% detection accuracy) on volunteer and clinical 3D echocardiograms.
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- 2014
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22. 34 Atrial fibrillation is a risk factor of heart failure in arrhythmogenic right ventricular cardiomyopathy
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Wlodarska, E.K., Konka, M., Walczak, F., and Hoffman, P.
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ATRIAL fibrillation , *HEART failure - Abstract
An abstract of the study "Atrial Fibrillation Is a Risk Factor of Heart Failure in Arrhythmogenic Right Ventricular Cardiomyopathy," by E. K. Wlodarska and colleagues is presented.
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- 2004
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23. Analysis of Patients with NET G1/G2 Neuroendocrine Tumors of the Small Intestine in the Course of Carcinoid Heart Disease-A Retrospective Study.
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Konsek-Komorowska SJ, Pęczkowska M, Kolasińska-Ćwikła AD, Cichocki A, Konka M, Roszkowska-Purska K, and Ćwikła JB
- Abstract
Neuroendocrine neoplasms of the small intestine (SI-NENs) are one of the most commonly recognized gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs). Carcinoid heart disease (CHD) is the primary cause of death in patients with the carcinoid syndrome (CS). The aim of this retrospective study was to evaluate possible factors impacting upon overall survival (OS) in subjects with both neuroendocrine tumors (NETs) G1/G2 of the small intestine (SI-NET) and CHD. Enrolled in our study of 275 patients with confirmed G1/G2 SI-NET, were 28 (10%) individuals with CHD. Overall survival was assessed using the Kaplan-Meier method. The Cox-Mantel test was used to determine how OS varied between groups. A Cox proportional hazards model was used to conduct univariate analyses of predictive factors for OS and estimate hazard ratios (HRs). Of the 28 individuals with confirmed carcinoid heart disease, 12 (43%) were found to have NET G1 and 16 (57%) were found to have NET G2. Univariate analysis revealed that subjects with CHD and without resection of the primary tumor had a lower OS. Our retrospective study observed that patients who presented with CHD and without resection of primary tumor had worse prognosis of survival. These results suggest that primary tumors may need to be removed when feasible, but further research is needed. However, no solid recommendations can be issued on the basis of our single retrospective study.
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- 2023
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24. Incidence and Predictors of Clinically Significant Bleedings after Transcatheter Left Atrial Appendage Closure.
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Zieliński K, Pracoń R, Konka M, Kruk M, Kępka C, Trochimiuk P, Dębski M, Kaczmarska E, Przyłuski J, Kowalik I, Dzielińska Z, Kurowski A, Witkowski A, and Demkow M
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- Female, Humans, Aged, Male, Incidence, Platelet Aggregation Inhibitors therapeutic use, Epistaxis complications, Treatment Outcome, Gastrointestinal Hemorrhage, Atrial Appendage surgery, Stroke epidemiology, Atrial Fibrillation epidemiology, Atrial Fibrillation therapy, Atrial Fibrillation complications
- Abstract
Background: Transcatheter left atrial appendage closure (LAAC) is performed in patients unsuitable for long-term anticoagulation, predominantly due to prior bleeding events. The study aimed to investigate the incidence and predictors of clinically significant bleeding (CSB) post-LAAC., Methods: Consecutive patients after LAAC with an Amplatzer or WATCHMAN device were analyzed (05.2014-11.2019). Bleeding was classified as CSB when associated with at least one of the following: death, ≥2 g/dL hemoglobin drop, ≥2 blood units transfusion, critical anatomic site, or hospitalization/invasive procedure., Results: Among 195 patients (age 74 (68-80), 43.1% females, HAS-BLED score 2.0 (2.0-3.0)), during median follow-up of 370 (IQR, 358-392) days, there were 15 nonprocedural CSBs in 14 (7.2%) patients. Of those, 9 (60.0%) occurred during postprocedural dual antiplatelet therapy (DAPT) (median 46 (IQR: 16-60) days post-LAAC) vs. 6 (40%) after DAPT discontinuation (median 124 (81-210) days post-LAAC), translating into annualized CSB rates of 14.0% (per patient-year on DAPT) vs. 4.6% (per patient-year without DAPT). In 92.9% (13/14) of patients, the post-LAAC nonprocedural CSB was a recurrence from the same site as bleeding pre-LAAC. In the multivariable model, admission systolic blood pressure (SBP) > 127 mmHg (HR = 10.73, 1.37-84.26, p = 0.024), epistaxis history (HR = 5.84, 1.32-25.89, p = 0.020), permanent atrial fibrillation (AF) (HR = 4.55, 1.20-17.20, p = 0.025), and prior gastrointestinal bleeding (HR = 3.35, 1.01-11.08, p = 0.048) predicted post-LAAC CSB., Conclusions: Nonprocedural CSBs after LAAC, with a similar origin as the pre-LAAC bleedings, were observed predominantly during postprocedural DAPT and predicted by elevated admission SBP, prior epistaxis, permanent AF, and gastrointestinal bleeding history. Whether a more reserved post-LAAC antiplatelet regimen and stringent blood pressure control may improve LAAC outcomes remains to be studied.
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- 2022
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25. Chromogranin A (CgA) as a biomarker in carcinoid heart disease and NETG1/G2 neuroendocrine neoplasms of the small intestine (SI-NENs) related carcinoid syndrome.
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Konsek-Komorowska SJ, Pęczkowska M, Kolasińska-Ćwikła AD, Konka M, Chrapowicki E, and Ćwikła JB
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- Biomarkers, Biomarkers, Tumor, Chromogranin A, Humans, Intestine, Small pathology, Retrospective Studies, Carcinoid Heart Disease complications, Carcinoid Heart Disease diagnosis, Neuroendocrine Tumors complications, Neuroendocrine Tumors diagnosis, Neuroendocrine Tumors pathology, Pancreatic Neoplasms diagnosis
- Abstract
Introduction: Progression of carcinoid syndrome (CS) to carcinoid heart disease (CHD) is difficult to predict. This retrospective analysis evaluates the use of chromogranin A (CgA), a biomarker widely used in the diagnosis of neuroendocrine tumours (NET), in monitoring CS and disease progression., Patients and Methods: 108 patients with confirmed CS, selected from a group of 351 patients with neuroendocrine neoplasms of the small intestine (SI-NENs), including NETG1 well 40% and NETG2 60% moderately differentiated NET. CgA concentration was measured during initial diagnosis and clinical follow up in 84 patients, 27 of them subsequently developed CHD. The patient's overall survival (OS) was evaluated using the Kaplan-Meier method., Results: Patients with CHD, were found to have significantly shorter OS than patients with CS but without CHD (67.22 vs. 73.03 months). Univariate and multivariate analyses revealed that initial high concentration of CgA and/or increased concentration of CgA is significantly associated with decreased median OS in patients with CS (p<0.05)., Conclusion: CgA has potential as a clinically useful biomarker in reporting disease status and predicting outcome in patients with CS and with CHD., (Copyright © 2021 Elsevier España, S.L.U. All rights reserved.)
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- 2022
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26. Residual stroke risk after left atrial appendage closure in patients with prior oral anticoagulation failure.
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Pracoń R, Zieliński K, Bangalore S, Konka M, Kruk M, Kępka C, Trochimiuk P, Dębski M, Przyłuski J, Kaczmarska E, Dzielińska Z, Kurowski A, Witkowski A, and Demkow M
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- Anticoagulants adverse effects, Hemorrhage chemically induced, Humans, Treatment Outcome, Atrial Appendage diagnostic imaging, Atrial Appendage surgery, Atrial Fibrillation complications, Atrial Fibrillation drug therapy, Atrial Fibrillation surgery, Ischemic Attack, Transient, Stroke diagnosis, Stroke epidemiology, Stroke etiology, Thrombosis
- Abstract
Background: Patients with atrial fibrillation (AF) and oral anticoagulation (OAC) failure may benefit from left atrial appendage closure (LAAC), however, the evidence is scarce. We report outcomes of LAAC in patients with OAC failure compared to those with classic indications of OAC contraindications., Methods: Prospective registry of LAAC with Amplatzer or WATCHMAN device followed by dual antiplatelet therapy (DAPT) was analyzed (05.2014-11.2019). The study group included patients with OAC failure defined as stroke/TIA/PE/LAA thrombus (n = 39) during OAC, whereas the control group consisted of patients with OAC contraindications (n = 156). Structured follow-up at 3, 6, and 12 months was done., Results: The study group compared to controls was younger [73 (IQR, 62-77) vs 74 (IQR, 68-81) years, P = 0.046], with higher CHA
2 DS2 -VASc [5.0 (IQR, 3.0-6.0) vs 4.0 (IQR, 3.0-5.0), P = 0.001)], lower HAS-BLED [2.0 (IQR, 1.0-3.0) vs 3.0 (IQR, 2.0-3.0), P = 0.006] and similar proportion of WATCHMAN implantations (43.6% vs 44.2%, P = 1.000). The reduction from CHA2 DS2 -VASc predicted to observed annual stroke/TIA/PE rate was markedly smaller in the study vs control group (14% vs 77%) with 10.3% vs 1.9% stroke/TIA/PE respectively (P = 0.031). The reduction from HAS-BLED predicted to observed annual major nonprocedural bleeding rate was higher (100% vs 7.4%) with 0.0% vs 5.1% major bleedings respectively (P = 0.361). The device-related thrombosis remained similar (13.2% vs 11.3%, P = 0.778)., Conclusions: Patients after LAAC for OAC failure and unremarkable prior bleeding history presented with high residual stroke and low bleeding risks. Therefore concomitant long-term OAC or prolonged DAPT should strongly be considered in this population., (Copyright © 2022 Elsevier B.V. All rights reserved.)- Published
- 2022
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27. What do we know about carcinoid heart disease in the present era?
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Pęczkowska M, Konsek-Komorowska SJ, Kolasińska-Ćwikła AD, Konka M, Michałowska I, and Ćwikła JB
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- Humans, Heart Valves surgery, Prognosis, Echocardiography, Biomarkers, Carcinoid Heart Disease diagnosis, Carcinoid Heart Disease therapy, Carcinoid Heart Disease pathology, Neuroendocrine Tumors pathology
- Abstract
Carcinoid heart disease (CHD) is a severe complication of carcinoid syndrome (CS) found primarily in patients with small intestine neuroendocrine neoplasms (SI-NENs). Patients who develop CHD have significantly worse morbidity and mortality outcomes, highlighting the importance of clinical practice recommendations for CHD screening, diagnosis, and treatment that are both consistent and practical. CHD is characterized by white plaque-like deposits on the endocardial surface of heart structures, generally affecting the right heart valves, causing tricuspid and pulmonary regurgitation and, less commonly, valve stenosis. Cardiac imaging is essential for both the diagnosis and management of CHD. Previously, imaging for CHD was mostly achieved by echocardiography, but more recently, imaging has become multimodal. N-terminal pro-B-type natriuretic peptide (NT-proBNP) and 5-hydroxyindoleacetic acid in the urine (u5-HIAA) are currently the most effective markers used in screening CS patients and evaluating CHD severity. Managing patients with CHD is challenging since both systemic malignant disease and cardiac involvement must be treated concurrently. Early diagnosis and surgical intervention when required are critical to patient prognosis, especially in those without primary tumor resection. Valve replacement surgery is the most effective treatment for patients with advanced carcinoid heart disease for alleviating cardiac symptoms and contributing to survival outcomes. To deliver effective patient treatment, multidisciplinary team collaboration is needed. This review summarizes current research findings on CHD pathogenesis, clinical and epidemiological features, useful biomarkers and imaging modalities, and treatment strategies.
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- 2022
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28. Prognostic value of computed tomography derived measurements of pulmonary artery diameter for long-term outcomes after transcatheter aortic valve replacement.
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Kalińczuk Ł, Chmielak Z, Dąbrowski M, Mazurkiewicz M, Stokłosa P, Skotarczak W, Mintz GS, Wolny R, Tyczyński P, Konka M, Michałowska A, Kowalik I, Demkow M, Michałowska I, and Witkowski A
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- Aged, 80 and over, Female, Humans, Male, Aortic Valve diagnostic imaging, Aortic Valve surgery, Multidetector Computed Tomography, Prognosis, Pulmonary Artery diagnostic imaging, Pulmonary Artery surgery, Risk Factors, Severity of Illness Index, Treatment Outcome, Aortic Valve Stenosis diagnostic imaging, Aortic Valve Stenosis surgery, Aortic Valve Stenosis complications, Frailty complications, Frailty surgery, Transcatheter Aortic Valve Replacement adverse effects
- Abstract
Background: An increase in pulmonary artery diameter (PAD) on multi-detector computed tomography (MDCT) may indicate pulmonary hypertension. We assessed the prognostic value of MDCT-derived measurements of PAD on outcomes after successful transcatheter aortic valve replacement (TAVR)., Methods: Consecutive patients treated with TAVR from February 2013 to October 2017, with a 68.8% rate of new generation valves, underwent pre-interventional MDCT with measurements of PAD (in the widest short-axis within 3 cm of the bifurcation) and ascending aortic diameter (AoD; at the level of the PAD). The PAD/AoD ratio was calculated. Patients with high-density lipoprotein cholesterol levels ≤46 mg/dl and C-reactive protein levels ≥0.20 mg/dl at baseline were identified as the frail group. One-year mortality was established for all subjects., Results: Among studied 266 patients (median age, 82.0 years; 63.5% women) those who died at 1 year (n = 34; 12.8%) had larger PAD and PAD/AoD (28.9 [5.0] vs. 26.5 [4.6] mm and 0.81 [0.13] vs. 0.76 [0.13] mm vs. the rest of the studied subjects; P = 0.005 and P = 0.02, respectively) but similar AoD. The cutoff value for the PAD to predict 1-year mortality was 29.3 mm (sensitivity, 50%; specificity, 77%; area under the curve, 0.65). Patients with PAD >29.3 mm (n = 72; 27%) had higher 1-year mortality (23.6% vs. 8.8%, log-rank P = 0.001). Baseline characteristics associated with PAD29.3 mm were a bigger body mass index, more frequent diabetes mellitus, more prior stroke/transient ischemic attacks and atrial fibrillation, and lower baseline maximal aortic valve gradient with higher pulmonary artery systolic pressure (PASP). PAD >29.3 mm and frailty, but not baseline PASP, remained predictive of 1-year mortality in the multivariable model (hazard ratio [HR], 2.221; 95%CI, 1.038-4.753; P = 0.04 and HR, 2.801; 95% CI, 1.328-5.910; P = 0.007, respectively)., Conclusion: PAD >29.3 mm on baseline MDCT is associated with higher 1-year mortality after TAVR, independently of echocardiographic measures of PH and frailty.
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- 2022
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29. Outcomes of cardiac surgical treatment for carcinoid heart disease.
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Konsek-Komorowska SJ, Kolasińska-Ćwikła AD, Różański J, Bartuś K, Kuriata J, Konka M, Sitkowska-Rysiak E, Michałowska I, Florczak E, Jaworska-Wilczyńska M, Januszewicz A, Hryniewiecki T, Ćwikła JB, and Pęczkowska M
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- Echocardiography, Humans, Carcinoid Heart Disease complications, Carcinoid Heart Disease surgery, Cardiac Surgical Procedures
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- 2022
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30. Implantable cardiac defibrillator events in patients with arrhythmogenic right ventricular cardiomyopathy.
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Woźniak O, Borowiec K, Konka M, Cicha-Mikołajczyk A, Przybylski A, Szumowski Ł, Hoffman P, Poślednik K, and Biernacka EK
- Subjects
- Adult, Death, Sudden, Cardiac epidemiology, Death, Sudden, Cardiac etiology, Death, Sudden, Cardiac prevention & control, Female, Follow-Up Studies, Humans, Male, Arrhythmogenic Right Ventricular Dysplasia complications, Arrhythmogenic Right Ventricular Dysplasia diagnosis, Arrhythmogenic Right Ventricular Dysplasia therapy, Defibrillators, Implantable adverse effects, Tachycardia, Ventricular complications, Tachycardia, Ventricular therapy
- Abstract
Objective: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is associated with a risk of sudden cardiac death. Optimal risk stratification is still under debate. The main purpose of this long-term, single-centre observation was to analyse predictors of appropriate and inappropriate implantable cardioverter-defibrillator (ICD) interventions in the population of patients with ARVC with a high risk of life-threatening arrhythmias., Methods: The study comprised 65 adult patients (median age 40 years, 48 men) with a definite diagnosis of ARVC who received ICD over a time span of 20 years in primary (40%) or secondary (60%) prevention of sudden cardiac death. The study endpoints were first appropriate and inappropriate ICD interventions (shock or antitachycardia pacing) after device implantation., Results: During a median follow-up of 7.75 years after ICD implantation, nine patients died and six individuals underwent heart transplantation. Appropriate ICD interventions occurred in 43 patients (66.2%) and inappropriate ICD interventions in 18 patients (27.7%). Multivariable analysis using cause-specific hazard model identified three predictors of appropriate ICD interventions: right ventricle dysfunction (cause-specific HR 2.85, 95% CI 1.56 to 5.21, p<0.001), age <40 years at ICD implantation (cause-specific HR 2.37, 95% CI 1.13 to 4.94, p=0.022) and a history of sustained ventricular tachycardia (cause-specific HR 2.55, 95% CI 1.16 to 5.63, p=0.020). Predictors of inappropriate ICD therapy were not found. Complications related to ICD implantation occurred in 12 patients., Conclusions: Right ventricle dysfunction, age <40 years and a history of sustained ventricular tachycardia were predictors of appropriate ICD interventions in patients with ARVC. The results may be used to improve risk stratification before ICD implantation., Competing Interests: Competing interests: None declared., (© Author(s) (or their employer(s)) 2022. No commercial re-use. See rights and permissions. Published by BMJ.)
- Published
- 2022
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31. What to look for in patient with continuous murmur and history of ventricular septal defect?
- Author
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Kwiatek-Wrzosek A, Kordybach-Prokopiuk M, Konka M, Michałowska I, and Hoffman P
- Subjects
- Heart Murmurs diagnosis, Heart Murmurs etiology, Humans, Physical Examination, Predictive Value of Tests, Heart Septal Defects, Ventricular diagnostic imaging, Sinus of Valsalva
- Abstract
During diagnostic process it is very important to conduct scrupulous interview and thorough physical examination. Properly interpreted auscultation phenomena allow for appropriate planning of further imaging studies., (© 2021. The Author(s), under exclusive licence to Springer Nature B.V.)
- Published
- 2021
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32. Imaging risk features for device related pulmonary artery injury after left atrial appendage closure with Amplatzer™ Amulet™ device.
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Pracoń R, De Backer O, Konka M, Kępka C, Kruk M, Trochimiuk P, Dębski M, Dzielińska Z, Søndergaard L, and Demkow M
- Subjects
- Cardiac Catheterization adverse effects, Humans, Pulmonary Artery diagnostic imaging, Treatment Outcome, Atrial Appendage diagnostic imaging, Atrial Fibrillation diagnostic imaging, Septal Occluder Device
- Abstract
Objectives: This study aimed to find imaging risk features for device related-pulmonary artery (PA) injury (DR-PAI) in patients after left atrial appendage closure (LAAC)., Background: Cardiac tamponade resulting from DR-PAI is a rare but life-threatening complication of LAAC., Methods: In vitro analysis of Amplatzer™ Amulet™ (Abbott, MN) device was done. Measurements of the distance between PA and Amplatzer lobe at its middle part, distal part, and along the stabilizing wires' trajectory (wires-to-PA distance) were taken in 100 consecutive patients on post-LAAC computed tomography (CT) studies. Clinical outcomes were collected., Results: In vitro analysis indicated that both middle and distal lobe had to be in close PA proximity (<1.5 mm) for the stabilizing wires to cause risk for DR-PAI, configuration called ''cuddling lobe orientation''. On CT measurements middle lobe-PA distance was 4.7 mm (IQR = 2.7-9.5), with close proximity in 4 (4%) patients, and distal lobe-PA distance was 3.2 mm (IQR = 1.8-7.2 mm), with close proximity in 17 (17%) patients. Stabilizing wires were pointing toward PA in 47 patients (47%) with median wire-to-PA distance 5.7 mm (IQR = 3.6-8.5 mm). ''Cuddling'' was found in 2 (2%) patients and resulted in shorter wires-to-PA distance vs no ''cuddling'' group (2.3 vs 5.8 mm p <.01). At 2.9 ± 1.0 yrs of follow-up, the two patients with ''cuddling lobe orientation'' on post-LAAC CT scan developed late cardiac tamponades (p <.001). One of those required surgery, which confirmed DR-PAI., Conclusions: ''Cuddling lobe orientation'' of Amulet device with the PA was associated with short wires-to-PA distance and late pericardial effusions, including DR-PAI. Hence, such device-to-PA configuration should be avoided., (© 2020 Wiley Periodicals LLC.)
- Published
- 2021
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33. "Chicken-Wing" Undersizing for "Sandwich" Left Atrial Appendage Closure Technique: An Image of Caution.
- Author
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Pracoń R, Konka M, Kȩpka C, Kaczmarska-Dyrda E, Michałowska I, and Demkow M
- Subjects
- Cardiac Catheterization adverse effects, Echocardiography, Transesophageal, Humans, Treatment Outcome, Atrial Appendage diagnostic imaging, Atrial Appendage surgery, Atrial Fibrillation diagnostic imaging, Atrial Fibrillation therapy, Cardiac Surgical Procedures, Stroke
- Abstract
Competing Interests: Funding Support and Author Disclosures Dr. Pracoń has received research grants and speaker fees from Abbott. Dr. Konka has received speaker fees and proctoring honoraria from Abbott. Dr. Demkow has received research grants, speaker fees, and proctoring honoraria from Abbott. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose.
- Published
- 2021
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34. How to Prevent Pulmonary Artery Wall Perforation Following Transcatheter Occlusion of Left Atrial Appendage.
- Author
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Demkow M, Konka M, Witkowski A, Pracoń R, Ścisło P, Huczek Z, Burysz M, Ogorzeja W, Suwalski G, Kurowski A, Kępka C, Klisiewicz A, Michałowska I, Dzielińska Z, Rudziński PN, and Kuśmierczyk M
- Subjects
- Cardiac Catheterization, Humans, Pulmonary Artery diagnostic imaging, Atrial Appendage diagnostic imaging, Atrial Appendage surgery, Atrial Fibrillation diagnosis, Stroke, Thromboembolism
- Published
- 2021
- Full Text
- View/download PDF
35. Myxoma in patients with hypertrophic obstructive cardiomyopathy. Retrospective single-center analysis.
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Brzozowski P, Tyczyński P, Michałowska I, Pronicki M, Konka M, Hoffman P, and Witkowski A
- Subjects
- Humans, Retrospective Studies, Cardiomyopathy, Hypertrophic complications, Cardiomyopathy, Hypertrophic diagnostic imaging, Myxoma complications, Myxoma diagnostic imaging, Myxoma surgery
- Published
- 2021
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- View/download PDF
36. Eleven-year follow-up of cardiac paraganglioma in a patient with SDHD C11X gene mutation.
- Author
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Michałowska AM, Ćwikła JB, Konka M, Kolasińska-Ćwikła A, Januszewicz A, Michałowska I, and Pęczkowska M
- Subjects
- Adult, Follow-Up Studies, Humans, Male, Mutation, Succinate Dehydrogenase genetics, Succinate Dehydrogenase metabolism, Adrenal Gland Neoplasms, Paraganglioma diagnostic imaging, Paraganglioma genetics, Paraganglioma surgery, Pheochromocytoma
- Published
- 2021
- Full Text
- View/download PDF
37. Intravenous antazoline, a first-generation antihistaminic drug with antiarrhythmic properties, is a suitable agent for pharmacological cardioversion of atrial fibrillation induced during pulmonary vein isolation due to the lack of influence on atrio-venous conduction and high clinical effectiveness (AntaEP Study).
- Author
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Farkowski MM, Maciag A, Kowalik I, Konka M, Szwed H, and Pytkowski M
- Subjects
- Administration, Intravenous, Aged, Antazoline pharmacology, Anti-Arrhythmia Agents pharmacology, Atrial Fibrillation surgery, Female, Histamine H1 Antagonists administration & dosage, Histamine H1 Antagonists pharmacology, Humans, Male, Middle Aged, Prospective Studies, Pulmonary Veins surgery, Antazoline administration & dosage, Anti-Arrhythmia Agents administration & dosage, Atrial Fibrillation drug therapy, Cryosurgery methods
- Abstract
Aims: Antazoline is a first-generation antihistaminic drug used primarily in eye drop formulations. When administered intravenously, antazoline displays antiarrhythmic properties resulting in a rapid conversion of recent-onset atrial fibrillation (AF) to sinus rhythm (SR). The aim of the study was to assess the influence of antazoline on atrio-venous conduction and other electrophysiological parameters in patients undergoing AF ablation., Methods: An experimental prospective study. Patients scheduled for the first-time AF ablation, in SR and not on amiodarone were enrolled. Atrio-venous conduction assessment and invasive electrophysiological study (EPS) were performed before and after intravenous administration of 250 mg of antazoline. In case of AF induction during EPS, antazoline was administered until conversion to SR or a cumulative dose of 300 mg., Results: We enrolled 14 patients: 13 (93%) men, mean age 63.4 (59.9-66.8) years, mean CHA
2 DS2 -VASc score 1.6 (1.0-2.2). Antazoline was administered in a mean dose 257.1 (246.7-267.6) mg. Pulmonary vein potentials and atrial capture during pulmonary vein stimulation were present before and after the administration of antazoline. Wenckebach point and atrial conduction times did not change significantly, but atrio-ventricular node effective refractory period improved-324.7 (275.9-373.5) ms vs 284.3 (256.2-312.4) ms, P = 0.02. Antazoline was effective in all 5 (100%) cases of AF induction during EPS. There were no serious adverse events., Conclusion: Due to the lack of influence on atrio-venous conduction and high clinical effectiveness, antazoline may be suitable for pharmacological cardioversion of AF occurring during AF ablation., (© 2019 The British Pharmacological Society.)- Published
- 2019
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38. Left atrial appendage closure for atrial fibrillation in a patient with hypertrophic cardiomyopathy in whom long-term oral anticoagulation was not feasible.
- Author
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Kłopotowski M, Konka M, Demkow M, Kukula K, and Witkowski A
- Abstract
Competing Interests: The authors declare no conflict of interest.
- Published
- 2019
- Full Text
- View/download PDF
39. Unroofed coronary sinus atrial septal defect.
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Zieliński P, Konka M, Hoffman P, Różański J, and Michałowska I
- Subjects
- Echocardiography, Transesophageal, Humans, Male, Middle Aged, Tomography, X-Ray Computed, Treatment Outcome, Cardiac Surgical Procedures methods, Coronary Sinus diagnostic imaging, Coronary Sinus surgery, Heart Septal Defects, Atrial diagnostic imaging, Heart Septal Defects, Atrial surgery
- Published
- 2019
- Full Text
- View/download PDF
40. Percutaneous Closure of Ventricular Septal Defect Resulting From Chest Stab Wound in an 18-Year-Old Boy.
- Author
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Pracon R, Grygoruk R, Konka M, Kepka C, and Demkow M
- Subjects
- Adolescent, Heart Injuries complications, Heart Injuries diagnosis, Heart Septal Defects, Ventricular diagnosis, Heart Septal Defects, Ventricular etiology, Heart Septum diagnostic imaging, Heart Septum surgery, Humans, Male, Printing, Three-Dimensional, Septal Occluder Device, Wounds, Stab diagnosis, Wounds, Stab surgery, Cardiac Catheterization methods, Cardiac Surgical Procedures methods, Heart Injuries surgery, Heart Septal Defects, Ventricular surgery, Heart Septum injuries, Surgery, Computer-Assisted methods, Wounds, Stab complications
- Published
- 2018
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- View/download PDF
41. Focus on the Perimeter and Skip the Balloon: Can Atrial Septal Defect Be Percutaneously Closed Without Balloon Sizing in the Era of 3-Dimensional Echocardiography?
- Author
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Henzel J, Konka M, Wójcik A, Rudziński PN, Pracoń R, Śmigielski W, Sitkowska-Rysiak E, Kurowski A, Dzielińska Z, Hoffman P, and Demkow M
- Subjects
- Adult, Aged, Feasibility Studies, Female, Heart Septal Defects, Atrial diagnostic imaging, Heart Septal Defects, Atrial physiopathology, Humans, Male, Middle Aged, Predictive Value of Tests, Prospective Studies, Prosthesis Design, Treatment Outcome, Cardiac Catheterization instrumentation, Echocardiography, Three-Dimensional, Echocardiography, Transesophageal, Heart Septal Defects, Atrial therapy, Septal Occluder Device
- Published
- 2018
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- View/download PDF
42. Cardiac arrest and ventricular arrhythmia in adults with Ebstein anomaly and left ventricular non-compaction.
- Author
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Kumor M, Lipczyńska M, Biernacka EK, Klisiewicz A, Wójcik A, Konka M, Kożuch K, Szymański P, and Hoffman P
- Subjects
- Adolescent, Adult, Aged, Aortic Valve abnormalities, Aortic Valve pathology, Arrhythmias, Cardiac complications, Bicuspid Aortic Valve Disease, Ebstein Anomaly complications, Echocardiography, Electrocardiography, Female, Heart Arrest complications, Heart Defects, Congenital complications, Heart Defects, Congenital physiopathology, Heart Septal Defects, Atrial complications, Heart Septal Defects, Atrial physiopathology, Heart Septal Defects, Ventricular complications, Heart Septal Defects, Ventricular physiopathology, Heart Valve Diseases pathology, Humans, Male, Middle Aged, Mitral Valve Prolapse complications, Mitral Valve Prolapse physiopathology, Mutation, Prevalence, Prognosis, Retrospective Studies, Wolff-Parkinson-White Syndrome complications, Wolff-Parkinson-White Syndrome physiopathology, Young Adult, Arrhythmias, Cardiac physiopathology, Ebstein Anomaly physiopathology, Heart Arrest physiopathology, Heart Ventricles physiopathology
- Abstract
Background: Ebstein anomaly is a complex, congenital heart defect that is associated with a variety of cardiac abnormalities. Studies found a similar sarcomere gene mutation in patients with Ebstein anomaly (EA) and patients with isolated left ventricular non-compaction (LVNC)., Aim: We aimed to show the prevalence of LVNC and its potential relationship with severe cardiac events (VT - ventricular tachycardia, cardiac arrest) in adult patients with EA., Methods: We conducted a retrospective search of our institutional database from 2010 to 2014 for patients with EA and reviewed patients' medical records (age, sex, clinical presentation, electrocardiographic, echocardiographic, and CMR - cardiac magnetic resonance features). We reviewed echocardiograms and CMR scans for concomitant morphological abnormalities (LVNC, PDA - patent ductus arteriosus, VSD - ventricular septal defect, ASD - atrial septal defect, mitral valve prolapse, BAV - bicuspid aortic valve, CoA - coarctation of aorta)., Results: The studied group consisted of 84 consecutive patients (mean age 38±15 years, 50 women) with EA. We found four patients (4.8%) with LVNC, two of them had cardiac arrest, one had VT, and one was symptomless, but had QTc prolongation in Holter recordings. Concomitant abnormalities were VSD (4.8%), PDA (1.2%), CoA (1.2%), mitral valve prolapse (1.2%), and BAV (2.4%). The most common anomaly was ASD type II - 23 patients (27.3%) and WPW - Wolff-Parkinson-White's syndrome - 9 patients (10.7%)., Conclusions: Non-compaction is a notable abnormality in adult patients with EA and it may affect their prognosis. Although other concomitant lesions were more common, only patients with LVNC suffered from cardiac arrest or ventricular arrhythmia., (Copyright © 2017 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved.)
- Published
- 2018
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43. Device Thrombosis After Percutaneous Left Atrial Appendage Occlusion Is Related to Patient and Procedural Characteristics but Not to Duration of Postimplantation Dual Antiplatelet Therapy.
- Author
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Pracon R, Bangalore S, Dzielinska Z, Konka M, Kepka C, Kruk M, Kaczmarska-Dyrda E, Petryka-Mazurkiewicz J, Bujak S, Solecki M, Pskit A, Dabrowska A, Sieradzki B, Plonski A, Ruzyllo W, Witkowski A, and Demkow M
- Subjects
- Atrial Fibrillation diagnostic imaging, Atrial Fibrillation epidemiology, Atrial Fibrillation physiopathology, Drug Administration Schedule, Drug Therapy, Combination, Echocardiography, Transesophageal, Humans, Incidence, Platelet Aggregation Inhibitors adverse effects, Poland epidemiology, Prospective Studies, Prosthesis Design, Registries, Risk Assessment, Risk Factors, Thrombosis diagnosis, Thrombosis prevention & control, Time Factors, Tomography, X-Ray Computed, Treatment Outcome, Atrial Appendage diagnostic imaging, Atrial Appendage physiopathology, Atrial Fibrillation therapy, Cardiac Catheterization adverse effects, Cardiac Catheterization instrumentation, Platelet Aggregation Inhibitors administration & dosage, Septal Occluder Device, Thrombosis epidemiology
- Abstract
Background: Device-related thrombus (DRT) after left atrial appendage occlusion is a worrisome finding with little knowledge about when to expect it and how to prevent it. This study sought to investigate correlates of DRT after left atrial appendage occlusion, its time of diagnosis, and particularly, association with postimplantation dual antiplatelet therapy duration., Methods and Results: Consecutive patients (n=102) after left atrial appendage occlusion with AMPLATZER Cardiac Plug/Amulet (n=59) or WATCHMAN (n=43) were included in a prospective registry (October 2011-May 2016). Follow-up was done at 1.5, 3 to 6, and 12 months postimplantation. DRT was classified as early (at 1.5 month), late (at 3-6 month), or very late (at 12-month follow-up). Postimplantation dual antiplatelet therapy was recommended for 30 to 180 days and decided independently by attending physicians. Final analysis included 99 patients, 42 (42.4%) females, with median CHA
2 DS2 -VASc of 4.0 (interquartile range [IQR], 3.0-5.0) and median HAS-BLED score of 2.0 (IQR, 1.0-3.0). DRTs were observed in 7 (7.1%) patients: 2 (28.6%) early, 2 (28.6%) late, and 3 (42.9%) very late. When compared with patients without DRT, those with DRT presented more often with a history of prior thromboembolism (5 [71.4%] versus 28 [30.4%]; P =0.04), had lower left ventricular ejection fraction (50.0 [IQR, 35.0-55.0] versus 60.0 [IQR, 55.0-66.0]; P <0.01), and had greater proportion of patients with deep device implantation (6 [85.7%] versus 36 [39.1%]; P =0.04) and with larger devices implanted (30.0 mm [IQR, 27.0-33.0] versus 25.0 mm [IQR, 24.0-28.0]; P <0.01). Postimplantation dual antiplatelet therapy duration was not different between the 2 groups (12.4 weeks [IQR, 6.0-49.7] with DRT versus 13.0 weeks [IQR, 7.3-26.0] without DRT; P =0.77)., Conclusions: In this real-world series, DRT was observed early, late, and very late after left atrial appendage occlusion. It was related to patient and procedural characteristics but not to postimplantation dual antiplatelet therapy duration., (© 2018 American Heart Association, Inc.)- Published
- 2018
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- View/download PDF
44. Percutaneous mitral balloon valvuloplasty: beyond classic indications.
- Author
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Tyczyński P, Chmielak Z, Rużyłło W, Demkow M, Dąbrowski M, Konka M, Gajda J, Stokłosa P, and Witkowski A
- Subjects
- Adult, Humans, Middle Aged, Retrospective Studies, Treatment Outcome, Balloon Valvuloplasty, Mitral Valve Stenosis surgery
- Abstract
Background and Aim: In patients with mitral stenosis (MS) percutaneous mitral balloon valvuloplasty (PMBV) is used to im-prove symptoms and prognosis. Although there is some evidence for potential long-term benefits from PMBV in asymptomatic patients with mitral valve area (MVA) between 1.0 and 1.5 cm2, there are no follow-up data on patients with symptomatic MS with MVA > 1.5 cm2, who underwent PMBV., Methods: We retrospectively analysed periprocedural results of 113 symptomatic patients who underwent PMBV for MS with MVA > 1.5 cm2 (group 1) and compared them with a control group of patients with MVA ≤ 1.5 cm2 (group 2). Clinical and procedural variables were compared between groups., Results: In group 1, PMBV resulted in a significant increase of MVA as well as a decrease of mean and maximal mitral gradients and mean left atrial pressure (LAP), and a subsequent decrease of mean and systolic pulmonary artery pressures (PAPs). Moreover, 6.3% of patients developed moderate to severe (3+) or severe (4+) post-procedural mitral regurgitation (MR). Post-procedural increase in MVA and decrease of LAP were more pronounced in group 2 than group 1 (∆MVA 0.74 cm2 vs. 0.41 cm2, p < 0.05, and ∆LAP 8.2 mmHg vs. 6.0 mmHg, p < 0.05). Nonetheless, no significant differences were observed for ∆ of mean and systolic PAPs. The grade of post-procedural MR was comparable between groups., Conclusions: PMBV is a feasible procedure in highly selected patients without classic echocardiographic indications. None-theless, it is associated with a small but non-negligible periprocedural risk of developing severe MR.
- Published
- 2018
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45. Transcatheter closure of patent foramen ovale for the secondary prevention of decompression illness in professional divers: a single-centre experience with long-term follow-up.
- Author
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Henzel J, Rudziński PN, Kłopotowski M, Konka M, Dzielińska Z, and Demkow M
- Subjects
- Adult, Female, Follow-Up Studies, Humans, Male, Middle Aged, Decompression Sickness prevention & control, Diving, Foramen Ovale, Patent surgery, Secondary Prevention
- Abstract
Background: Patent foramen ovale (PFO) with occasional right-to-left shunting is associated with an increased risk of decompression illness (DCI). Divers with a history of repetitive or severe DCI and diagnosed with PFO should be considered for transcatheter closure if they wish to continue with unrestricted diving., Aim: To summarise our centre's experience in transcatheter PFO closure in professional divers with a history of DCI., Methods: A follow-up of 11 consecutive divers (nine males, two females) in whom device PFO closure was performed between 2001 and 2015 was carried out by phone contact. Available medical records and diving logbooks were reviewed to determine individual DCI symptomatology, indications to the procedure, and to evaluate modifications in the diving practice., Results: Each patient experienced at least one event of DCI before the procedure, and eight patients experienced more than one event. Total number of reported events was 62. The vast majority of events (97%) followed dives consistent with safe decompression policies. The median follow-up was 91 (minimum nine, maximum 172) months. No complications of the intervention were observed. All patients returned to unrestricted, deep diving, performing a total of 3610 dives with the median number of 225 dives (lower quartile value: 82.5 dives, upper quartile value: 725 dives). The majority of subjects dived as deep as they did before the intervention, or deeper, achieving mean maximum depth of 93.8 ± 35.6 m (vs. 89.7 ± 25.9 m before the intervention, p = 0.71). No episodes of DCI were reported during the follow-up period., Conclusions: Transcatheter closure of PFO appears to be reasonably effective in secondary prevention of DCI associated with intra-cardiac shunting.
- Published
- 2018
- Full Text
- View/download PDF
46. Is Transcatheter Tricuspid Valve-In-Valve Implantation Feasible in the Presence of Right Atrial Thrombus?
- Author
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Henzel J, Dzielińska Z, Konka M, Dąbrowski M, Protasiewicz M, Witkowski A, and Demkow M
- Subjects
- Cardiac Catheterization methods, Computed Tomography Angiography, Echocardiography, Doppler, Color, Female, Heart Valve Diseases diagnosis, Heart Valve Diseases physiopathology, Heart Valve Prosthesis Implantation methods, Humans, Prosthesis Design, Prosthesis Failure, Recovery of Function, Rheumatic Heart Disease diagnosis, Rheumatic Heart Disease physiopathology, Risk Factors, Thrombosis diagnostic imaging, Treatment Outcome, Tricuspid Valve diagnostic imaging, Tricuspid Valve physiopathology, Bioprosthesis, Cardiac Catheterization instrumentation, Heart Valve Diseases surgery, Heart Valve Prosthesis, Heart Valve Prosthesis Implantation adverse effects, Heart Valve Prosthesis Implantation instrumentation, Rheumatic Heart Disease surgery, Thrombosis etiology, Tricuspid Valve surgery
- Abstract
The case is reported of a successful transcatheter implantation of an Edwards SAPIEN 3 valve (29 mm) into a failing tricuspid bioprosthesis (Sorin Pericarbon, 31 mm). The procedure was performed in a 69-year-old woman with post-rheumatic mitral and tricuspid valve disease. Multiple previous cardiac surgeries precluded the use of another surgical approach. A large, organized, two-piece thrombus in the enlarged right atrium was not considered an absolute contraindication to the procedure. The SAPIEN 3 valve was implanted under general anesthesia, via a femoral venous access, under three-dimensional transesophageal echocardiography guidance. Postoperatively, the systolic right ventricular pressure was increased from 35 to 52 mmHg, but good function of the implanted valve was confirmed with transthoracic echocardiography. The clinical outcome was favorable and the patient was discharged home 72 h after the intervention. Video 1: Transthoracic echocardiography. Tricuspid color Doppler flow after the procedure. Video 2: Fluoroscopy. Fully expanded Edwards SAPIEN 3 valve in the tricuspid position. Video 3: Fluoroscopy. Expansion of the Edwards SAPIEN 3 valve on the balloon. Video 4: Fluoroscopy. Introduction of the Edwards SAPIEN 3 valve into the right atrium. Video 5: Transthoracic echocardiography. Tricuspid color Doppler flow before the procedure.
- Published
- 2017
47. A 51-year-old patient with carcinoid heart disease and severe tricuspid regurgitation.
- Author
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Florczak E, Pęczkowska M, Konka M, Różański J, and Kolasińska-Ćwikła A
- Subjects
- Bioprosthesis, Carcinoid Heart Disease drug therapy, Female, Humans, Ileal Neoplasms pathology, Liver Neoplasms complications, Liver Neoplasms secondary, Middle Aged, Somatostatin therapeutic use, Tricuspid Valve Insufficiency diagnostic imaging, Tricuspid Valve Insufficiency surgery, Carcinoid Heart Disease complications, Heart Valve Prosthesis Implantation, Tricuspid Valve, Tricuspid Valve Insufficiency etiology
- Published
- 2017
- Full Text
- View/download PDF
48. Percutaneous occlusion of the left atrial appendage with complex anatomy facilitated with 3D-printed model of the heart.
- Author
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Pracon R, Grygoruk R, Dzielinska Z, Kepka C, Dąbrowska A, Konka M, Jazwiec P, Reczuch K, Witkowski A, and Demkow M
- Subjects
- Aged, 80 and over, Anatomic Variation, Female, Humans, Atrial Fibrillation surgery, Endovascular Procedures methods, Heart Atria diagnostic imaging, Printing, Three-Dimensional
- Published
- 2016
- Full Text
- View/download PDF
49. Percutaneous left atrial appendage occlusion - treatment outcomes and 6 months of follow-up - a single-center experience.
- Author
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Karczewski M, Woźniak S, Skowronek R, Burysz M, Fischer M, Anisimowicz L, Demkow M, Konka M, and Ogorzeja W
- Abstract
Aim: To present the results of treatment and evaluate 6 months of follow-up in a group of patients with non-valvular atrial fibrillation, who underwent the procedure of percutaneous left atrial appendage occlusion (PLAAO)., Material and Methods: Percutaneous left atrial appendage occlusion was performed in 34 patients with non-valvular atrial fibrillation and contraindications for oral anticoagulation therapy. The risk of thromboembolic and bleeding complications was determined based on the CHA2DS2VASc and HAS-BLED scales. The Amplatzer Amulet system from St. Jude Medical was used. On the first postoperative day, all patients were started on double antiplatelet therapy with 75 mg/day of acetylsalicylic acid (ASA) and 75 mg/day of clopidogrel (CLO). On the 30(th) postoperative day, the efficacy of the antiplatelet therapy was assessed with impedance aggregometry using a Multiplate analyzer (Roche). Echocardiographic examinations were performed intraoperatively and on the first postoperative day; subsequently, follow-up examinations were conducted 1 and 6 months after the implantation., Results: In all patients, proper occluder position was observed throughout the follow-up. No leakage or thrombi around the implants were found. No strokes or bleeding complications associated with the antiplatelet therapy were observed. Multiplate assessment of platelet activity was conducted in 20 out of 34 patients. The efficacy of ASA treatment was demonstrated in all patients; no response to clopidogrel treatment was observed in 5 out of 20 patients. One patient suffered from cardiac tamponade, which required the performance of full sternotomy. Local complications (hematomas of the inguinal region) were observed in 3 patients. One of the patients died for reasons unrelated to the procedure., Conclusions: Percutaneous left atrial appendage occlusion is an effective procedure in patients with non-valvular atrial fibrillation and contraindications for chronic anticoagulation therapy. Further observation is necessary to evaluate the longterm results.
- Published
- 2016
- Full Text
- View/download PDF
50. Noninvasive pacing during transfemoral implantation of the Edwards SAPIEN valve for tricuspid valve bioprosthesis stenosis.
- Author
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Demkow M, Rużyłło W, Bujak S, Konka M, Szatkowski P, and Lubiszewska B
- Published
- 2016
- Full Text
- View/download PDF
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