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1. Paradoxical activation of alternative pro-survival pathways determines resistance to MEK inhibitors in chronic lymphocytic leukaemia.

Author

Chen Y, Germano S, Shelmani G, Kluczna D, Jayne S, Dyer MJS, and Macip S

Subjects
Humans, Phosphoinositide-3 Kinase Inhibitors, Protein Kinase Inhibitors pharmacology, Signal Transduction, Tumor Cells, Cultured, raf Kinases metabolism, Drug Resistance, Neoplasm, Leukemia, Lymphocytic, Chronic, B-Cell metabolism, MAP Kinase Signaling System drug effects
Published
2018
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