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5 results on '"Karney, Michael J."'

4. RAPID PREPARATION OF A CEREBELLIN POSITIONAL SCAN LIBRARY.

Author

Karney, Michael J.

Subjects
*PEPTIDE synthesis, *BIOLOGICAL aggregation, *MICROWAVES, *FLUIDICS, *CHEMICAL synthesis
Abstract

Peptide synthesis often suffers from long reaction times and low yields due to problems such as aggregation. Microwave energy can help break up these aggregates improving the synthesis quality while, in combination with advanced fluidics, speeding up the synthesis rate. [ABSTRACT FROM AUTHOR]

Published
2014

5. MICROWAVE REACTIONS GENERATING A GASEOUS BY PRODUCT.

Author

Karney, Michael J.

Subjects
*MICROWAVES, *MICROWAVE chemistry, *HIGH temperature chemistry, *HIGH pressure (Science), *CHEMICAL reactions
Abstract

The pressure monitoring devices on most microwave reactors which seal the reaction vessel are designed for high temperature/high pressure reactions and can-not remove undesired gaseous by-products that can stall a reaction. CEM's Activent® pressure device for the Discover® SP microwave synthesizer provides the capability to successfully manage both types of reactions easily. [ABSTRACT FROM AUTHOR]

Published
2014

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