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7. Risk Assessment on Use of Lactobacillus rhamnosus (LGG) as an Ingredient in Infant Formula and Baby Foods (II)

Author

Rimstad, Espen, primary, Andersen, Lene Frost, primary, Frølich, Wenche, primary, Frøyland, Livar, primary, Høiby, Ernst Arne, primary, Kapperud, Georg, primary, Haugen, Margaretha, primary, Lassen, Jørgen, primary, Lunestad, Bjørn-Tore, primary, Meltzer, Helle Margrete, primary, Narvhus, Judith, primary, Nesbakken, Truls, primary, Nygård, Karin, primary, Olsvik, Ørjan, primary, Paulsen, Jan Erik, primary, Robertson, Lucy, primary, Tranulis, Michael, primary, Tryland, Morten, primary, Vainio, Kirsti, primary, and Halvorsen, Ragnhild, primary

Published
2021
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11. Assessment of Benefits and Risks of Probiotics in Processed Cerealbased Baby Foods Bifidobacterium Lactis Bb12

Author

Halvorsen, Ragnhild, primary, Narvhus, Judith, primary, Lassen, Jørgen, primary, Midtvedt, Tore, primary, Rugtveit, Jarle, primary, Yazdankhah, Siamak, primary, Andersen, Lene Frost, primary, Frølich, Wenche, primary, Frøyland, Livar, primary, Haugen, Margaretha, primary, Kapperud, Georg, primary, Lunestad, Bjørn Tore, primary, Høiby, Ernst Arne, primary, Meltzer, Helle Margrete, primary, Nesbakken, Truls, primary, Nygård, Karin, primary, Olsvik, Ørjan, primary, Paulsen, Jan Erik, primary, Robertson, Lucy, primary, Tranulis, Michael, primary, Tryland, Morten, primary, and Rimstad, Espen, primary

Published
2021
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13. Assessment of Benefits and Risks of Probiotics in Processed Cereal-based Baby Foods Lactobacillus Paracasei ssp. Paracasei F19

Author

Halvorsen, Ragnhild, primary, Lassen, Jørgen, primary, Midtvedt, Tore, primary, Narvhus, Judith, primary, Rugtveit, Jarle, primary, Yazdankhah, Siamak, primary, Eckner, Karl, primary, Frølich, Wenche, primary, Frøyland, Livar, primary, Iversen, Per Ole, primary, Kapperud, Georg, primary, Lillegaard, Inger Therese L., primary, Lunestad, Bjørn-Tore, primary, Lyche, Jan Ludvig, primary, Mansoor, Azam, primary, Meltzer, Helle Margrete, primary, Nesbakken, Truls, primary, Nygård, Karin, primary, Robertson, Lucy, primary, Tranulis, Michael, primary, Tryland, Morten, primary, and Haugen, Margaretha, primary

Published
2021
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17. Handlingsrommet etter påvisning av skrantesyke (Chronic Wasting Disease, CWD) på Hardangervidda – grunnlag for fremtidige Vitenskapelig uttalelse fra Vitenskapskomiteen for Mat og Miljø (VKM)

Author

Ytrehus, Bjørnar, Asmyhr, Maria Gulbrandsen, Hansen, Helge, Nilsen, Erlend Birkeland, Mysterud, Atle, Strand, Olav, Tranulis, Michael A., Våge, Jørn, Kapperud, Georg, Madslien, Knut Ivar Engesæter, Rueness, Eli Knispel, and Wasteson, Yngvild

Subjects
Wild reindeer hunt, Skrantesyke, Chronic wasting disease, Matematikk og naturvitenskap: 400 [VDP], Mathematics and natural scienses: 400 [VDP], Villrein, Wild rein deer, Villreinfangst, VDP::Matematikk og naturvitenskap: 400, VDP::Mathematics and natural scienses: 400
Published
2021

19. Oppdatert kunnskap om det zoonotiske potensialet av skrantesjuke ved håndtering av slakt og konsum av kjøtt. Vitenskapelig uttalelse fra faggruppen for hygiene og smittestoffer i Vitenskapskomiteen for mat og miljø

Author

Tranulis, Michael A., Grahek-Ogden, Danica, Kapperud, Georg, Pahnke, Jens, Aspholm, Marina Elisabeth, Jore, Solveig, Melby, Kjetil Klaveness, Møretrø, Trond, Nesbakken, Truls, Robertson, Lucy, and Skjerdal, Olaug Taran

Subjects
Slaughtering, VDP::Andre landbruksfag: 919, Other agricultural sciences: 919 [VDP], Slakting, Andre landbruksfag: 919 [VDP], Kjøttkvalitet, Skrantesyke, Risikovurdering, VDP::Other agricultural sciences: 919, Chronic wasting disease, Zoonoser, Zoonoses, Flesh quality, Reinsdyr, Reindeer, Risk assessment
Published
2021

20. Risk ranking and source attribution of food- and waterborne pathogens for surveillance purposes. Opinion of the Panel on Biological Hazards of the Norwegian Scientific Committee for Food and Environment

Author

Skjerdal, Olaug Taran, Aspholm, Marina Elisabeth, Grahek-Ogden, Danica, Jore, Solveig, Kapperud, Georg, Melby, Kjetil Klaveness, Møretrø, Trond, Myrmel, Mette, Nesbakken, Truls, Robertson, Lucy, and Strachan, Norval

Subjects
VDP::Klinisk veterinærmedisinske fag: 950, Klinisk veterinærmedisinske fag: 950 [VDP], Clinical veterinary sciences: 950 [VDP], VDP::Clinical veterinary sciences: 950
Published
2021

22. Molecular epidemiology of Salmonella enterica serovar Typhimurium isolates determined by pulsed-field gel electrophoresis: comparison of isolates from avian wildlife, domestic animals, and the environment in Norway

Author

Refsum, Thorbjorn, Heir, Even, Kapperud, Georg, Vardund, Traute, and Holstad, Gudmund

Subjects
Salmonella typhimurium -- Environmental aspects, Salmonella typhimurium -- Physiological aspects, Gel electrophoresis -- Usage, Epidemiology -- Research, Biological sciences
Abstract

Research has been conducted on Salmonella enterica serovar Typhimurium isolates from avian domestic and wildlife animals. The study of molecular epidemology of these isolates has been carried out via the use of pulsed-field gel electrophoresis and computerized numerical analysis, and the results are reported.

Published
2002

23. Salmonellae in avian wildlife in Norway from 1969 to 2000

Author

Refsum, Thorbjorn, Handeland, Kjell, Baggesen, Dorte Lau, Holstad, Gudmund, and Kapperud, Georg

Subjects
Salmonella -- Environmental aspects, Salmonella -- Physiological aspects, Bacteriophages -- Research, Plasmids -- Physiological aspects, Bacterial infections -- Causes of, Biological sciences
Abstract

Research has been conducted on salmonella infection in wild-living birds in Norway. The authors summarize the records of Salmonella detection in wild birds and compare the isolates via the use of plasmid profile analysis and phage typing.

Published
2002

24. Detection of small numbers of Campylobacter jejuni and Campylobacter coli cells in environmental water, sewage, and food samples by a seminested PCR assay

Author

Vardund, Traute, Waage, Astrid S., Lund, Vidar, and Kapperud, Georg

Subjects
Campylobacter -- Environmental aspects, Sewage -- Microbiology, Food -- Microbiology, Bacteria -- Environmental aspects, Water pollution -- Environmental aspects, Microbial contamination -- Environmental aspects, Biological sciences
Abstract

Small numbers of Campylobacter jejuni and Campylobacter coli cells have been detected in environmental water, sewage and food samples using a seminested PCR assay. Water and sewage samples were filtered, while the filters were enriched overnight in a nonselective medium. The approach proved effective for specific detection of Campylobacter jejuni or Campylobacter coli in drinking water as well as environmental water, sewage and food samples with high concentrations of background organisms.

Published
1999

29. Detection of pathogenic Yersinia enterocolitica in foods and water by immunomagnetic separation, nested polymerase chain reactions, and colorimetric detection of amplified DNA

Author

Kapperud, Georg, Vardund, Traute, Skjerve, Eystein, Hornes, Erik, and Michaelsen, Terje E.

Subjects
Yersinia enterocolitica -- Identification and classification, Immunotaxonomy -- Usage, Polymerase chain reaction -- Usage, Gene amplification -- Analysis, Biological sciences
Abstract

A two-step polymerase chain reaction (PCR) method, using the rested pairs of primers unique to the yadA gene of Yersinia enterocolitica, was devised. The PCR assay revealed common pathogenic serogroups in three continents, and distinguished pathogenic Y. enterocolitica from Y. pseudotuberculosis. Seeded food and water samples were employed to measure the performance of this method.

Published
1993

30. Outbreak of Yersinia enterocolitica serogroup O:9 infection and processed pork, Norway

Author

Grahek-Ogden, Danica, Schimmer, Barbara, Cudjoe, Kofitsyo S., Nygard, Karin, and Kapperud, Georg

Subjects
Yersinia infections -- Causes of, Yersinia infections -- Complications and side effects, Yersinia infections -- Diagnosis, Yersinia infections -- Care and treatment, Pork -- Risk factors, Pork -- Health aspects
Abstract

An outbreak involving 11 persons infected with Yersinia Enterocolitica 0:9 was investigated in Norway in February 2006. A case-control study and microbiologic investigation indicated a ready-to-eat pork product as the [...]

Published
2007

31. Årsrapport Utbrudd av smittsomme sykdommer i Norge i 2017. Vevbasert system for utbruddsvarsling (Vesuv)

Author

Macdonald, Emily Ann, Berg, Thale Cathrine, Brandal, Lin Cathrine T., Kacelnik, Oliver, Kapperud, Georg, Lange, Heidi, Tønnesen, Ragnhild, Vold, Line, and Nygård, Karin Maria

Abstract

I 2017 ble det varslet 162 utbrudd med totalt 2 320 rapporterte sykdomstilfeller. Dette er litt mer enn i 2016, men på samme nivå som årene før. Antallet syke varierte fra 2 til 230 per utbrudd. Ved 36 av utbruddene var det mistanke om smitte fra næringsmidler. Over 60 prosent av alle utbrudd (101 utbrudd) ble varslet fra helseinstitusjoner. For utbrudd i helseinstitusjoner var norovirus (47 utbrudd), meticillinresistente Staphylococcus aureus (MRSA) (11 utbrudd), influensavirus (11 utbrudd) og vankomycinresistente enterokokker (VRE) (9 utbrudd) de hyppigst forekommende agens. Det vanligste agens angitt ved næringsmiddelbårne utbrudd var norovirus (7 utbrudd), etterfulgt av enterohemoragisk E. coli (EHEC) og Campylobacter (3 utbrudd hver). Det er antakelig fortsatt en stor underrapportering av utbrudd. Rask og mer fullstendig varsling av utbrudd gjør at sentrale myndigheter kan se det enkelte utbrudd i nasjonal og internasjonal sammenheng. De kan dermed danne seg et bilde av den epidemiologiske situasjon i landet som helhet, varsle internasjonale instanser dersom det er nødvendig og gi råd og informasjon der det er behov.

Published
2018

36. Microorganisms in Biostimulants

Author

Joner, Erik, primary, Skjerve, Eystein, primary, Sundheim, Leif, primary, Tronsmo, Arne, primary, Wastson, Yngvild, primary, Eckner, Karl, primary, Kapperud, Georg, primary, Lassen, Jørgen Fredrik, primary, Narvhus, Judith, primary, Nesbakken, Truls, primary, Robertson, Lucy, primary, Rosnes, Jan Thomas, primary, Skjerdal, Olaug Taran, primary, and Vold, Line, primary

Published
2019
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38. CWD in Norway

Author

Tranulis, Michael, primary, Tryland, Morten, primary, Kapperud, Georg, primary, Skjerve, Eystein, primary, Gudding, Roar, primary, Grahel-Ogden, Danica, primary, Eckner, Karl, primary, Lassen, Jørgen, primary, Narvhus, Judith, primary, Nesbakken, Truls, primary, Robertson, Lucy, primary, Rosnes, Jan Thomas, primary, Skjerdal, Olaug Taran, primary, Vold, Line, primary, Yazdankhah, Siamak, primary, and Wastson, Yngvild, primary

Published
2019
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39. CWD in Norway – A State of Emergency for the Future of Cervids (Phase II)

Author

Hansen, Helge, primary, Kapperud, Georg, primary, Mysterud, Atle, primary, Solberg, Erling J., primary, Strand, Olav, primary, Tranulis, Michael, primary, Ytrehus, Bjørnar, primary, Asmyhr, Maria Gulbrandsen, primary, Grahel-Ogden, Danica, primary, Eckner, Karl, primary, Lassen, Jørgen, primary, Narvhus, Judith, primary, Nesbakken, Truls, primary, Robertson, Lucy, primary, Rosnes, Jan Thomas, primary, Skjerdal, Olaug Taran, primary, Skjerve, Eystein, primary, Vold, Line, primary, and Wastson, Yngvild, primary

Published
2019
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41. The Link between Antimicrobial Resistance and the Content of Potentially Toxic Metals in Soil and Fertilising Products

Author

Wastson, Yngvild, primary, Skjerve, Eystein, primary, Yazdankhah, Siamak, primary, Eckner, Karl, primary, Kapperud, Georg, primary, Lassen, Jørgen Fredrik, primary, Narvhus, Judith, primary, Nesbakken, Truls, primary, Robertson, Lucy, primary, Rosnes, Jan Thomas, primary, Skjerdal, Olaug Taran, primary, and Vold, Line, primary

Published
2019
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43. Risk Assessment of Specific Strains of Lactobacillus acidophilus Used as "Other Substances"

Author

Yazdankhah, Siamak, primary, Grahek-Ogden, Danica, primary, Eckner, Karl, primary, Kapperud, Georg, primary, Lassen, Jørgen, primary, Narvhus, Judith, primary, Nesbakken, Truls, primary, Robertson, Lucy, primary, Rosnes, Jan Thomas, primary, Skjerdal, Olaug Taran, primary, Skjerve, Eystein, primary, Vold, Line, primary, and Wasteson, Yngvild, primary

Published
2019
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44. Risk Assessment of Specific Strains of Lactobacillus plantarum Used as "Other Substances"

Author

Yazdankhah, Siamak, primary, Grahek-Ogden, Danica, additional, Eckner, Karl, additional, Kapperud, Georg, additional, Lassen, Jørgen, additional, Narvhus, Judith, additional, Nesbakken, Truls, additional, Robertson, Lucy, additional, Rosnes, Jan Thomas, additional, Skjerdal, Olaug Taran, additional, Skjerve, Eystein, additional, Vold, Line, additional, and Wasteson, Yngvild, additional

Published
2018
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45. Risk Assessment of Streptococcus thermophilus Used as "Other Substances"

Author

Grahek-Ogden, Danica, primary, Eckner, Karl, additional, Kapperud, Georg, additional, Lassen, Jørgen, additional, Narvhus, Judith, additional, Nesbakken, Truls, additional, Robertson, Lucy, additional, Rosnes, Jan Thomas, additional, Skjerdal, Olaug Taran, additional, Skjerve, Eystein, additional, Vold, Line, additional, Yazdankhah, Siamak, additional, and Wasteson, Yngvild, additional

Published
2018
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46. Outbreak of haemolytic uraemic syndrome in Norway caused by stx2-positive Escherichia coli O103:H25 traced to cured mutton sausages

Author

Lindstedt Bjørn-Arne, Lassen Jørgen, Eriksen Hanne-Merete, Nygard Karin, Schimmer Barbara, Brandal Lin T, Kapperud Georg, and Aavitsland Preben

Subjects
Infectious and parasitic diseases, RC109-216
Abstract

Abstract Background On 20–21 February 2006, six cases of diarrhoea-associated haemolytic uraemic syndrome (HUS) were reported by paediatricians to the Norwegian Institute of Public Health. We initiated an investigation to identify the etiologic agent and determine the source of the outbreak in order to implement control measures. Methods A case was defined as a child with diarrhoea-associated HUS or any person with an infection with the outbreak strain of E. coli O103 (defined by the multi-locus variable number tandem repeats analysis (MLVA) profile) both with illness onset after January 1st 2006 in Norway. After initial hypotheses-generating interviews, we performed a case-control study with the first fifteen cases and three controls for each case matched by age, sex and municipality. Suspected food items were sampled, and any E. coli O103 strains were typed by MLVA. Results Between 20 February and 6 April 2006, 17 cases were identified, of which 10 children developed HUS, including one fatal case. After pilot interviews, a matched case-control study was performed indicating an association between a traditional cured sausage (odds ratio 19.4 (95% CI: 2.4–156)) and STEC infection. E. coli O103:H25 identical to the outbreak strain defined by MLVA profile was found in the product and traced back to contaminated mutton. Conclusion We report an outbreak caused by a rare STEC variant (O103:H25, stx2-positive). More than half of the diagnosed patients developed HUS, indicating that the causative organism is particularly virulent. Small ruminants continue to be important reservoirs for human-pathogen STEC. Improved slaughtering hygiene and good manufacturing practices for cured sausage products are needed to minimise the possibility of STEC surviving through the entire sausage production process.

Published
2008
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47. Prevalence and characterization of integrons in blood culture Enterobacteriaceae and gastrointestinal Escherichia coli in Norway and reporting of a novel class 1 integron-located lincosamide resistance gene

Author

Gjernes Elisabet, Leegaard Truls M, Lindstedt Bjørn-Arne, Heir Even, and Kapperud Georg

Subjects
Therapeutics. Pharmacology, RM1-950, Infectious and parasitic diseases, RC109-216, Microbiology, QR1-502
Abstract

Abstract Background Class 1 integrons contain genetic elements for site-specific recombination, capture and mobilization of resistance genes. Studies investigating the prevalence, distribution and types of integron located resistance genes are important for surveillance of antimicrobial resistance and to understand resistance development at the molecular level. Methods We determined the prevalence and genetic content of class 1 integrons in Enterobacteriaceae (strain collection 1, n = 192) and E. coli (strain collection 2, n = 53) from bloodstream infections in patients from six Norwegian hospitals by molecular techniques. Class 1 integrons were also characterized in 54 randomly selected multiresistant E. coli isolates from gastrointestinal human infections (strain collection 3). Results Class 1 integrons were present in 10.9% of the Enterobacteriaceae blood culture isolates of collection 1, all but one (S. Typhi) being E. coli. Data indicated variations in class 1 integron prevalence between hospitals. Class 1 integrons were present in 37% and 34% of the resistant blood culture isolates (collection 1 and 2, respectively) and in 42% of the resistant gastrointestinal E. coli. We detected a total of 10 distinct integron cassette PCR amplicons that varied in size between 0.15 kb and 2.2 kb and contained between zero and three resistance genes. Cassettes encoding resistance to trimethoprim and aminoglycosides were most common. We identified and characterized a novel plasmid-located integron with a cassette-bound novel gene (linF) located downstream of an aadA2 gene cassette. The linF gene encoded a putative 273 aa lincosamide nucleotidyltransferase resistance protein and conferred resistance to lincomycin and clindamycin. The deduced LinF amino acid sequence displayed approximately 35% identity to the Enterococcus faecium and Enterococcus faecalis nucleotidyl transferases encoded by linB and linB' Conclusions The present study demonstrated an overall low and stable prevalence of class 1 integron gene cassettes in clinical Enterobacteriaceae and E. coli isolates in Norway. Characterization of the novel lincosamide resistance gene extends the growing list of class 1 integron gene cassettes that confer resistance to an increasing number of antibiotics.

Published
2004
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