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A technique for staging the generation of obstructive thrombi in the coronary arteries of conscious dogs is described. At thoracotomy, electrodes are placed in the lumina of coronary artery branches. When thrombus generation in proximity to the intraluminal electrode tip is desired, anodal current is applied to the exteriorised end of the electrode.In each of nine anaesthetised adult mongrel dogs two to seven intracoronary electrodes were implanted for a total of 35. One to 75 days later, 50 to 800 μA anodal current was applied to 16 electrodes for 30 min to 48 h. Upon autopsy, thrombi in various stages of organisation were found in proximity to the intracoronary portion of 15 electrodes. Six electrodes were found to be damaged or broken.In contrast, only four of the 13 control electrodes were sites of thrombus formation. In seven dogs tissue sections indicated either myocardial ischaemia or infarct in regions whose perfusion was blocked by thrombi.This method may provide for discretionary generation of intracoronary thrombi in the desired quantity, at the preferred site(s), at selected times of onset. Consequently, it offers the possibility of adjusting the onset, severity, and time course of myocardial ischaemia. [ABSTRACT FROM PUBLISHER]

The importance of including precordial leads in evaluating donor atrial activity and QRS voltage variations after cardiac allotransplantation in puppies was established. Double atrial activity appeared early and consistently post-operatively. Reduced maximal QRS vector was a sign of rejection. Earlier rejection signs included sinus bradycardia, transient sinus arrest, and nodal rhythm. [ABSTRACT FROM PUBLISHER]

Assesses a study done on the use of electric stimulation in controlling adynamic ileus. Review of related literature; Description of the electrostimulation preparation used to reactivate peristalsis in dogs with adynamic intestines; Results of the study when applied to patients who had undergone routine abdominal surgery.

Focuses on the problem and the technical method for constructing fresh autogenous arterial tubular grafts, of any required diameter, from any segments of the splenic artery. Factor affecting the use of preserved aortic homografts; Success of the preserved aortic homografts used in bridging defects in the aorta; Preservation of the histologic integrity of the muscle cells and elastic laminae of the media of the autogenous arterial transplants.

The article presents an obituary for Norman E. Shumway, the father of heart transplantation and one of the pre-eminent surgeons of his time.