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5. Turkish Validation of the Rapid Interactive Screening Test for Autism in Toddlers.

Author

Kadak, Muhammed Tayyib, Serdengeçti, Nihal, Seçen Yazıcı, Meryem, Sandıkçı, Tuncay, Aydın, Aybike, Koyuncu, Zehra, Meral, Yavuz, Haşimoğlu, Abas, Çalışkan, Yasin, Bayraktar, Gizem, Can Öztürk, Elif, Gökler, Mehmet Enes, Choueiri, Roula, and Tarakçıoğlu, Mahmut Cem

Subjects
*DIAGNOSIS of autism, *RESEARCH methodology evaluation, *CHILD psychiatry, *DESCRIPTIVE statistics, *EARLY intervention (Education), *NEUROPSYCHOLOGICAL tests, *RESEARCH methodology, *MEDICAL screening, *EARLY diagnosis, *SENSITIVITY & specificity (Statistics), *MEDICAL referrals, RESEARCH evaluation
Abstract

This study aims to investigate the validation of the Rapid Interactive Screening Test for Autism in Toddlers (RITA-T) in Turkish toddlers between 18 and 36 months of age. Children aged 18–36 months were referred to the department of child psychiatry for concerns of autism spectrum disorder, language disorder, developmental delay, and typically developing children were enrolled. A total of 81 toddlers participating in the study received clinical interviews according to the Diagnostic and Statistical Manual of Mental Disorders (5th ed.) and the Childhood Autism Rating Scale. They received the translated RIT-T from reliably trained and blinded providers. Parents completed the Modified Checklist for Autism in Toddlers form. A cut-off score was calculated based on the sensitivity, specificity, positive, and negative predictive values of the RITA-T total score that best differentiates autism spectrum disorder diagnosis. For all participants, the RITA-T total score correlated with the Modified Checklist for Autism in Toddlers (r = 0.715) and the Childhood Autism Rating Scale total score (r = 0.825). Using a cut-off score of ⩾17, the RITA-T had a sensitivity of.90 and a specificity of.927 for identifying autism spectrum disorder risk. The area under the curve was.977. Our findings demonstrate that the RITA-T is effective in Turkish toddlers for the early identification of autism spectrum disorder, early intervention settings, and allowing access to treatment. It is important to diagnose autism spectrum disorder at an early age and to start an early intervention program without delay. In this study, we aimed to validate the Rapid Interactive Screening Test for Autism in Toddlers (RITA-T) in a group of Turkish children and found that the RITA-T which has been shown to be a valid and reliable screening test for 18- to 36-month-old children in studies conducted in different countries, is also valid in Turkish children. Similar to previous studies, our results showed that the RITA-T has good sensitivity and specificity in distinguishing children with autism spectrum disorder. We think that our study will contribute to the timely initiation of early intervention programs for many children with autism by enabling a valid test to be used in screening programs. [ABSTRACT FROM AUTHOR]

Published
2024
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8. Attachment and comorbid anxiety in ADHD.

Author

Akman, Hazal, Serdengeçti, Nihal, Yavuz, Mesut, Kadak, Muhammed Tayyib, Ercan, Oya, and Doğangün, Burak

Subjects
HYPERKINESIA, IMPULSIVE personality, ATTENTION-deficit hyperactivity disorder, ATTACHMENT behavior, ANXIETY, EMOTION regulation, COMORBIDITY
Abstract

Anxiety comorbidity is quite common in children with attention-deficit hyperactivity disorder (ADHD). What is known about the relationship between anxiety, attachment and emotion regulation in such children is still limited. We aimed to investigate the associations between attachment, emotion regulation and comorbid anxiety in children with ADHD. 100 children with ADHD and 100 children without any diagnosis aged 8–13 years were included. After the participants were clinically evaluated, Turgay ADHD Scale, Emotion Regulation Checklist, Revised Child Anxiety and Depression Scale-Child Version (RCADS-CV) and Kerns' Security Scale were completed. According to the RCADS-CV scores, ADHD/ANX(+), ADHD/ANX(−), and control groups were formed. The emotional lability/negativity levels were higher in the ADHD groups compared to the non-ADHD controls. Paternal and maternal attachment security levels were lower in the ADHD/ANX(+) group compared to the controls. The regression analysis indicated that higher hyperactivity/impulsivity symptom levels and lower maternal attachment quality were associated with higher anxiety in children with ADHD. These results suggest that focusing on attachment quality and emotion regulation problems may be significant in management of core symptoms and comorbid anxiety problems in children with ADHD. [ABSTRACT FROM AUTHOR]

Published
2024
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9. The Relation Between Academic Procrastination, Symptoms of Attention Deficit Hyperactivity Disorder, and Academic Performance in Medical Students.

Author

Sönmez, Özge, Koyuncu, Zehra, Atlı, Zeynep, Hacıkerimoğlu, Özlem, Tekgöl, Nermin Cansu, and Kadak, Muhammed Tayyib

Subjects
ATTENTION-deficit hyperactivity disorder, MEDICAL students, ACADEMIC achievement, PROCRASTINATION, STUDENT volunteers
Abstract

Objective: Procrastination is putting off intended tasks that are necessary to reach a goal. Attention deficit hyperactivity disorder (ADHD) is characterized by excessive inattention, impulsivity, and hyperactivity. We aimed to understand the association between academic performance, procrastination, and ADHD. Methods: A group of medical students were screened for procrastination and ADHD by self-report scales. First-, second-, third-, and fourth-year medical students were included in the study. Background information, including birth orders, parents’ education status, department satisfaction, sex, and age, were collected. Tuckman procrastination scale and the adult ADHD self-report scale were applied. Grade point average (GPA) was noted, and it was accepted as an indicator of academic performance. Results: A total of 318 (age: 19.7 ± 1.6; 46% male) volunteer medical students were included. Students with lower GPA had higher tendency to procrastinate than those with high GPA. Even though ADHD self-reported scores were positively correlated with procrastination scores, regression analyses showed that there was no statistically significant association between ADHD symptoms and academic performance. Conclusion: In conclusion, procrastination led to poor academic performance, and nearly half of the students had a tendency to procrastinate. Moreover, students with probable ADHD symptoms tended to procrastinate more. Therefore, students with poor academic performance should be screened for procrastination and ADHD symptoms. [ABSTRACT FROM AUTHOR]

Published
2023
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15. Association of Dissociation with Suicide Attempt and Non-Suicidal Self Injury in Adolescents with a History of Sexual Abuse.

Author

Bikmazer, Alperen, Koyuncu, Zehra, Kavruk Erdim, Nese, Kadak, Muhammed Tayyib, Tarakcioglu, Mahmut Cem, Gokler, Enes, Gormez, Vahdet, and Ozer, Omer Akil

Subjects
SELF-injurious behavior, SUICIDAL behavior, SEX crimes
Abstract

Objective: Dissociative symptoms are considered risk factors for suicide and non-suicidal self-injury (NSSI). In this study, the relationship between suicidal behaviors and NSSI with dissociative symptoms in adolescents with a history of Child Sexual Abuse (CSA) was investigated. Methods: A total of 100 adolescents with a history of CSA were evaluated with a detailed forensic psychiatric interview. Dissociative symptoms were measured with the self-report Adolescent Dissociative Experiences Scale (A-DES) and the parent-reported Child Dissociative Checklist (CDC). Results: While dissociative symptoms did not differ between adolescents with and without suicide attempts (CDC; p =.068 and A-DES; p =.060), they were significantly higher in adolescents with non-suicidal self-harming behavior (CDC; p <.001 and A-DES; p =.001). Suicide attempts and NSSI were more common in those who reported genital touching as a type of sexual abuse (respectively, p =.003; p =.048). In regression analysis; history of psychiatric treatment (OR = 9.09 [95% CI = 1.52, 54.29]) and NSSI (OR = 8.18 [95% CI = 2.01, 33.23]) were independently associated with suicide attempts. In addition, parent-reported dissociative symptoms (CDC scores) (OR = 1.27 [95% CI = 1.06, 1.53] and suicide attempt (OR = 8.09 [95%CI = 1.96,33.42] showed independent association with NSSI. Conclusions: Dissociative symptoms may be predictive factors for NSSI and should be considered in risk assessment of adolescents with a history of CSA. [ABSTRACT FROM AUTHOR]

Published
2023
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20. Emotion Recognition Skill in Specific Learning Disorder and Attention-Deficit Hyperactivity Disorder.

Author

Albayrak, Zeynep Seda, Kadak, Muhammed Tayyib, Gürbüz, Hatice Gözde Akkın, and Doğangün, Burak

Subjects
*LEARNING disabilities, *ATTENTION-deficit hyperactivity disorder, *EMOTION recognition, *SOCIAL skills education, *EYE examination, *LEARNING ability, *FACIAL expression & emotions (Psychology), *SOCIAL skills, *YOUTH with attention-deficit hyperactivity disorder
Abstract

Objective: Social difficulties can affect both academic and relational-social functioning in common neurodevelopmental disorders such as attention-deficit hyperactivity disorder and specific learning disorder. It is known that social cognitive skills directly affect social functioning. The aim in this study is to examine the social cognitive skill of facial emotion recognition in children with attention-deficit hyperactivity disorder and specific learning disorder and to investigate whether literacy learning is related to emotion recognition. Methods: In the study, we compared the emotion recognition skill of 41 children with attention-deficit hyperactivity disorder, 50 with specific learning disorder, and 43 typically developed children using the Reading Mind in the Eyes Test. In addition, we evaluated the relationship between children's emotion recognition ability and literacy learning time. Results: Attention-deficit hyperactivity disorder and specific learning disorder groups did not show a statistically significant difference in terms of Reading Mind in the Eyes Test scores, but both groups had lower scores than their typically eveloped peers (P < .001). In addition, we found that low Reading Mind in the Eyes Test scores were associated with late learning in reading and writing (P < .001, r = -.033). Conclusion: This study found that the specific learning disorder and attention-deficit hyperactivity disorder groups showed similar but poorer impact recognition skills than their typically developed peers. In addition, we showed that literacy learning speed is related to emotion recognition. [ABSTRACT FROM AUTHOR]

Published
2022
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21. Parental psychological distress associated with COVID-19 outbreak: A large-scale multicenter survey from Turkey

Author

Bıkmazer, Alperen, primary, Kadak, Muhammed Tayyib, additional, Görmez, Vahdet, additional, Doğan, Uğur, additional, Aslankaya, Zeynep Dilara, additional, Bakır, Fulya, additional, Tarakçıoğlu, Mahmut Cem, additional, Kaya, İlyas, additional, Gümüş, Yusuf Yasin, additional, Esin, İbrahim Selçuk, additional, Karayağmurlu, Ali, additional, Adak, İbrahim, additional, Yaylacı, Ferhat, additional, Güller, Barış, additional, Tanır, Yaşar, additional, Koyuncu, Zehra, additional, Serdengeçti, Nihal, additional, Ermiş, Çağatay, additional, Kaçmaz, Gül Bilgin, additional, Gülşen, Hatice, additional, Doğru, Hicran, additional, Bayati, Mohammed Al, additional, Üstündağ, Büşra, additional, Gökler, Enes, additional, Özyurt, Gonca, additional, Baykara, Burak, additional, Ekinci, Özalp, additional, Başgül, Şaziye Senem, additional, Görmez, Aynur, additional, Emiroğlu, Neslihan İnal, additional, Türkçapar, Hakan, additional, and Öztürk, Mücahit, additional

Published
2020
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23. Tables – Parental psychological distress associated with COVID-19 outbreak: A large-scale multicenter survey from Turkey

Author

Bıkmazer, Alperen, Kadak, Muhammed Tayyib, Vahdet Görmez, Uğur Doğan, Aslankaya, Zeynep Dilara, Bakır, Fulya, Tarakçıoğlu, Mahmut Cem, İlyas Kaya, Gümüş, Yusuf Yasin, İbrahim Selçuk Esin, Karayağmurlu, Ali, İbrahim Adak, Yaylacı, Ferhat, Barış Güller, Yaşar Tanır, Koyuncu, Zehra, Serdengeçti, Nihal, Çağatay Ermiş, Kaçmaz, Gül Bilgin, Gülşen, Hatice, Doğru, Hicran, Bayati, Mohammed Al, Büşra Üstündağ, Gökler, Enes, Özyurt, Gonca, Baykara, Burak, Özalp Ekinci, Şaziye Senem Başgül, Görmez, Aynur, Emiroğlu, Neslihan İnal, Türkçapar, Hakan, and Öztürk, Mücahit

Subjects
FOS: Psychology, FOS: Clinical medicine, 170199 Psychology not elsewhere classified, 110319 Psychiatry (incl. Psychotherapy)
Abstract

Tables for Parental psychological distress associated with COVID-19 outbreak: A large-scale multicenter survey from Turkey by Alperen Bıkmazer, Muhammed Tayyib Kadak, Vahdet Görmez, Uğur Doğan, Zeynep Dilara Aslankaya, Fulya Bakır, Mahmut Cem Tarakçıoğlu, İlyas Kaya, Yusuf Yasin Gümüş, İbrahim Selçuk Esin, Ali Karayağmurlu, İbrahim Adak, Ferhat Yaylacı, Barış Güller, Yaşar Tanır, Zehra Koyuncu, Nihal Serdengeçti, Çağatay Ermiş, Gül Bilgin Kaçmaz, Hatice Gülşen, Hicran Doğru, Mohammed Al Bayati, Büşra Üstündağ, Enes Gökler, Gonca Özyurt, Burak Baykara, Özalp Ekinci, Şaziye Senem Başgül, Aynur Görmez, Neslihan İnal Emiroğlu, Hakan Türkçapar and Mücahit Öztürk in International Journal of Social Psychiatry

Published
2020
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24. Parental psychological distress associated with COVID-19 outbreak: A large-scale multicenter survey from Turkey.

Author

Bıkmazer, Alperen, Kadak, Muhammed Tayyib, Görmez, Vahdet, Doğan, Uğur, Aslankaya, Zeynep Dilara, Bakır, Fulya, Tarakçıoğlu, Mahmut Cem, Kaya, İlyas, Gümüş, Yusuf Yasin, Esin, İbrahim Selçuk, Karayağmurlu, Ali, Adak, İbrahim, Yaylacı, Ferhat, Güller, Barış, Tanır, Yaşar, Koyuncu, Zehra, Serdengeçti, Nihal, Ermiş, Çağatay, Kaçmaz, Gül Bilgin, and Gülşen, Hatice

Subjects
*RESEARCH, *MOTHERS, *PSYCHOLOGY of parents, *MULTIPLE regression analysis, *MENTAL health, *SURVEYS, *EMPLOYMENT, *DESCRIPTIVE statistics, *ODDS ratio, *PSYCHOLOGICAL distress, *COVID-19 pandemic, *MENTAL illness
Abstract

Aims: Pandemics can cause substantial psychological distress; however, we do not know the impact of the COVID-19 related lockdown and mental health burden on the parents of school age children. We aimed to comparatively examine the COVID-19 related the stress and psychological burden of the parents with different occupational, locational, and mental health status related backgrounds. Methods: A large-scale multicenter online survey was completed by the parents (n = 3,278) of children aged 6 to 18 years, parents with different occupational (health care workers—HCW [18.2%] vs. others), geographical (İstanbul [38.2%] vs. others), and psychiatric (child with a mental disorder [37.8%]) backgrounds. Results: Multivariable logistic regression analysis showed that being a HCW parent (odds ratio 1.79, p <.001), a mother (odds ratio 1.67, p <.001), and a younger parent (odds ratio 0.98, p =.012); living with an adult with a chronic physical illness (odds ratio 1.38, p <.001), having an acquaintance diagnosed with COVID-19 (odds ratio 1.22, p =.043), positive psychiatric history (odds ratio 1.29, p <.001), and living with a child with moderate or high emotional distress (odds ratio 1.29, p <.001; vs. odds ratio 2.61, p <.001) were independently associated with significant parental distress. Conclusions: Parents report significant psychological distress associated with COVID-19 pandemic and further research is needed to investigate its wider impact including on the whole family unit. [ABSTRACT FROM AUTHOR]

Published
2021
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25. ASSOCIATION BETWEEN COGNITIVE BELIEFS AND OBSESSIVE COMPULSIVE SYMPTOMS IN NON-CLINICAL POPULATION

Author

ALBAYRAK, Zeynep Seda, TARAKÇIOĞLU, Mahmut Cem, and KADAK, Muhammed Tayyib

Subjects
Cognitive Beliefs,Obsessive Compulsive Symptoms,adolescent, Medicine, humanities, Tıp
Abstract

Introduction: Both adults and children with OCD, vary in terms ofinsight related to the accuracy of their dysfunctional beliefs, ranging fromacknowledging the fact that the beliefs are irrational to being completelyconvinced the beliefs are true.Materialand Method: Participants consisted of 264 adolescents, aged from 12 to 16 years. Mean age of thesample was 13.56 (SD±1.11) years. The Obsessive Compulsive Inventory-Revised(OCI-R), State Trait Anxiety Inventoryfor Children (STAI-C), Obsessive Beliefs Questionnaire-Child Version (OBQ-CV),and Meta-Cognitions Questionnaire for Children (MCQ-C) were applied. Results:Themean scores of subscales of OCI-R andOBQ are not different in regarding togender (p> .05) but STAI-C,MCQ-Positive and MCQ-Negative are differed (p

Published
2018

26. Türkiye birinci basamak sağlık çalışanları otizm farkındalık eğitimi çalışması

Author

TUMBA, CAN, ERDOĞAN, İLKER, ADALETLİ, HİLAL, KANDEMİR, HASAN, GÜZEL, ESRA, SANBERK, SATI, YILMAZ, DİNÇER, KALYONCU, TUĞBA, ARGÜS ÇILDIR, DENİZ, YÜZÜGÜLDÜ, ONUR, CEVHER BİNİCİ, NAGİHAN, ESİN, İBRAHİM SELÇUK, ABANOZ, ELİF, KARAMAN, SELÇUK, TAŞLIBEYAZ, ELİF, MADAN ÖZDEMİR, RABİA, ALATAŞ, ESRA, MOTAVALLI MUKADDES, NAHİT, DURSUN, ONUR BURAK, İŞERİ, ELVAN, ÜNALDI, NURDAN, CHATIP CHOUSEIN ACHMET, CHASAN, NALBANT, KEVSER, SERTÇELİK, MEHMET, KESKİNER, ÖZLEM, FİDAN, SANİYE TÜLİN, ERAY, ŞAFAK, TOKLU YALVAŞ, ÇİĞDEM, OCAKOĞLU, BİNAY KAYAN, KELEŞ, MEHRİBAN, CÖMERTOĞLU ARSLAN, SEMİHA, KALAYCI, BİLGE MERVE, TURAL HESAPÇIOĞLU, SELMA, TAŞTORUN, YASEMİN, ÇÖP, ESRA, ÜNERİ, ÖZDEN ŞÜKRAN, GÜNEY, ESRA, HEKİM, ÖZLEM, ŞENSES DİNÇ, GÜLSER, FIRAT, SÜMEYRA, GÜL, HESNA, UZUN, ÖZLEM, ATABEY, ENDER, ŞENTÜRK, EKREM, ÇİMEN, İREM DAMLA, KARAYAĞMURLU, ALİ, AKSU, SEHRA, GÜLEŞ, ZAFER, ÖZKAN, SELÇUK, AVCİL, SİBELNUR, KARAKOÇ DEMİRKAYA, SEVCAN, ERKAN, MUSTAFA CAN, KILINÇEL, ŞENAY, ÇARKAXHIU BULUT, GRESA, KALA, SERHAT, TAŞYÜREK, EMİNE, ERDEN, SEMİH, BOZKURT, ABDULLAH, BOSTAN, RECEP, KÜÇÜK, ÖNDER, METİN DUMAN, HANDAN, AYAZ, NEŞE, USTA, MİRAÇ BARIŞ, COŞKUN, MURAT, TARAKÇIOĞLU, MAHMUT CEM, YILMAZ, SULTAN SEVAL, GÜMÜŞTAŞ, FUNDA, MUTLU, CANER, YILMAZ, SEMRA, KARA, TAYFUN, AKIN, ELİF, ÖZBEK, FATİH, GÜNEŞ, HATİCE, KOCAMAN, ORHAN, BAHALI, MUSTAFA KAYHAN, ADAK, İBRAHİM, KOÇAK YILMAZ, KÜBRA, ÇAKIR, MAHMUT, ASLAN, ZEYNEP, LUŞ, MELEK GÖZDE, AYAZ, GÜÇLÜ, BAHADIR, ALİYE TUĞBA, BENK DURMUŞ, FATMA, ARMAN, AYŞE, AYAZ, AYŞE BURCU, YUSUFOĞLU, CANAN, PERDAHLI FİŞ, NEŞE, SABUNCUOĞLU, OSMAN TALAT, ERBİLGİN GÜN, SEDA, UYSAL, TACİSER, BÜYÜKASLAN, AYŞE, TUNA, ŞEYMA, ÜNVER, HATİCE, POYRAZ FINDIK, ONUR TUĞÇE, GÜNDOĞDU, ÜMMÜGÜLSÜM, ÇERİ, VEYSİ, TÜFEKÇİ, ALGUN, ŞEN DEMİRDÖĞEN, EZGİ, TAN, MERYEM YELDA, NARİN COŞKUN, GÖZDE, ALGEDİK, PINAR, ÇELEBİ, FAHRİ, KAYTANLI, UMUT, MEHTAR, MUHAMMED, MUTLUER, TUBA, DOĞANGÜN, BURAK, BİNGÖL ÇAĞLAYAN, HÜLYA, BİLGİN, NUŞİN, KAYA, İLYAS, HOCAOĞLU, SEVGİ, KARAÇETİN, YASEMİN, YALÇIN, ÖZHAN, KILIÇOĞLU, ALİ GÜVEN, SOYLU, NUSRET, KADAK, MUHAMMED TAYYİB, BABADAĞI, ZEHRA, ALTUN VARMIŞ, DİLEK, BİLGİNER, TUĞBA, İNCE, CANAN, YILMAZ, SEHERYELİ, GÜVEN, GÖKÇEN, ÇEVİKASLAN, AHMET, DERİN, SONGÜL, GÖKALP ÖZCAN, BURCU, NASIROĞLU, SERHAT, GÜNDÜZ, YAĞMUR, ASLAN, CİHAN, HARMANCI, HALİME, SAPMAZ, DİCLE, KABA, DUYGU, KARA, MAHMUT ZABİT, KILIÇ, HİLAL TUĞBA, KARA, HALİL, SÜRER ADANIR, ASLI, TUNCER, ÖMER FARUK, EROL, ALİ, YÜCEL, GÖKHUN İNAN, KINAY, DUYGU, ŞAHİN, MEHMET, ULAŞ, GÖZDE, KINIK, MEHMET FATİH, UZUNÇİÇEK, AYLA, AKTAŞ TERZİOĞLU, MERVE, YEKTAŞ, ÇİĞDEM, YURTERİ ÇETİN, NİHAL, ÇİÇEK, SEVGİ, ERGÜVEN DEMİRTAŞ, MERVE, GÜNEŞ, ADEM, ŞAHİN, BERKAN, ÖZEN, EMEL, KARABUCAK, BAŞAK, GÜRBÜZ ÖZGÜR, BÖRTE, GÜNTEPE, DİLEK, ÖZHAN İBİŞ, ESRA, AYYILDIZ, DİDEM, and ÇITAK KARABOĞA, AYŞE ECE

Published
2018

30. Symposium Oral Presentations

Author

Çeri, Veysi, primary, Aykutlu, Hasan Cem, additional, Görker, Işık, additional, Akça, Ömer Faruk, additional, Tarakçıoğlu, Mahmut Cem, additional, Aksoy, Umut Mert, additional, Kaya, Heysem, additional, Sertdemir, Merve, additional, İnce, Ezgi, additional, Kadak, Muhammed Tayyib, additional, Yalçın, Gökşen Yüksel, additional, Guliyev, Cavid, additional, Bilgiç, Ayhan, additional, Çiftçi, Elvan, additional, Tekin, Kinyas, additional, Tuna, Zehra Olcay, additional, Oğuzdoğan, Burcu, additional, Duman, Nagihan Saday, additional, Semerci, Bengi, additional, Üneri, Özden Şükran, additional, Karabekiroglu, Koray, additional, Mutluer, Tuba, additional, Nebioglu, Melike, additional, Başgül, Şaziye Senem, additional, Naharcı, Mehmet İlkin, additional, Maden, Özgür, additional, Hocaoğlu, Çiçek, additional, Durmaz, Onur, additional, Usta, Haluk, additional, Boşgelmez, Şükriye, additional, Puşuroğlu, Meltem, additional, Eser, Hale Yapıcı, additional, Kaçar, Murat, additional, Çakır, Mahmut, additional, Karatepe, Hasan Turan, additional, Işık, Ümit, additional, Kara, Halil, additional, Yeloğlu, Çağdaş Hünkar, additional, Yazıcı, Esra, additional, Gündüz, Anıl, additional, Karataş, Kader Semra, additional, Yavlal, Figen, additional, Uzun, Necati, additional, Yazici, Ahmet Bulent, additional, Bodur, Şahin, additional, Aslan, Esma Akpınar, additional, Batmaz, Sedat, additional, Çelik, Feyza, additional, Açıkel, Sadettin Burak, additional, Topal, Zehra, additional, Altunsoy, Neslihan, additional, Tulacı, Özge Demircan, additional, Demirel, Ömer Faruk, additional, Çıtak, Serhat, additional, Çak, Halime Tuna, additional, Artık, Abdül Baki, additional, Özçetin, Adnan, additional, Özdemir, Ilker, additional, Çelik, Fatma Gül Helvacı, additional, Kültür, Sadriye Ebru Çengel, additional, Çipil, Arif, additional, Ay, Rukiye, additional, Arman, Ayşe Rodopman, additional, Yazıcı, Kemal Utku, additional, Yuce, Arzu Erkan, additional, Yazıcı, İpek Perçinel, additional, Kurt, Emel, additional, Kaçar, Anıl Şafak, additional, Erbil, Nurhan, additional, Poyraz, Cana Aksoy, additional, Altın, Gamze Ergil, additional, Şahin, Berkan, additional, Kılıç, Özge, additional, Turan, Şenol, additional, Aydın, Memduha, additional, Kuru, Erkan, additional, Bozkurt, Abdullah, additional, Güleç, Hüseyin, additional, İnan, Merve Yalçınay, additional, Şevik, Ali Emre, additional, Baykal, Saliha, additional, Karaer, Yusuf, additional, Yanartaş, Omer, additional, Aksu, Hatice, additional, Ergün, Serhat, additional, Görmez, Aynur, additional, Yıldız, Mesut, additional, Bag, Sevda, additional, Özkanoğlu, Ferda Korkmaz, additional, Caliskan, Mecit, additional, Yaşar, Alişan Burak, additional, Konuk, Emre, additional, Altın, Murat, additional, Bulut, Serkut, additional, Bulut, Gresa Çarkaxhiu, additional, Tulacı, Rıza Gökçer, additional, Küpeli, Neşe Yorguner, additional, Enver, Necati, additional, Tasci, İlker, additional, Kani, Ayşe Sakallı, additional, Bahçeci, Bülent, additional, Oğuz, Gülay, additional, Şenyuva, Gülçin, additional, Ünal, Gülşen Teksin, additional, Yektaş, Çiğdem, additional, Örüm, Mehmet Hamdi, additional, Göka, Erol, additional, Gıca, Şakir, additional, Şahmelikoğlu, Özge, additional, Dinç, Gülser Şenses, additional, Erşan, Serpil, additional, Erşan, Erdal, additional, Ceylan, Mehmet Fatih, additional, Hesapçıoğlu, Selma Tural, additional, Solmaz, Mustafa, additional, Balcioglu, Yasin Hasan, additional, Cetin, Mesut, additional, Tosun, Musa, additional, Yurteri, Nihal, additional, Ulusoy, Sevinc, additional, Karadere, Mehmet Emrah, additional, Kivrak, Yüksel, additional, and Görmez, Vahdet, additional

Published
2018
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31. Heterogeneity of subclinical autistic traits among parents of children with autism spectrum disorder: Identifying the broader autism phenotype with a data-driven method

Author

Sarac, Tugba, KÖSE, SEZEN, KADAK, Muhammed Tayyib, AYDIN, AYDAN, and BORA, İBRAHİM EMRE

Abstract

Clinical diagnosis of autism spectrum disorder (ASD) can be conceptualized as the extreme end of the distribution of subclinical autistic traits related to genetic susceptibility factors (broad autism phenotype (BAP)) in the general population. Subclinical autistic traits are significantly more common among unaffected first-degree relatives of probands with autism. However, there is a significant heterogeneity of autistic traits in family members of individuals with ASD and severity of autistic traits are not significantly different from controls in the majority of these relatives. The current study investigated the heterogeneity of autistic traits using latent class analysis (LCA) of the Autism Spectrum Quotient (AQ) ratings of 673 parents of children with ASD and 147 parents of typically developing children. Two distinct subgroups, including a "low-scoring" and a "high-scorer (BAP)" groups, were found. In comparison to control parents, a significantly larger proportion (21.1% vs. 7.5%) of parents of ASD were members of BAP group. Communication subscale made a distinctive contribution to the separation of high and low-scoring groups (d=2.77). Further studies investigating neurobiological and genetic biomarkers and stability of these two subgroups over time are important for understanding the nature of autistic traits in the general population. Autism Res2017, 10: 321-326. (c) 2016 International Society for Autism Research, Wiley Periodicals, Inc.

Published
2017

32. Do low serum uch-l1 and tdp-43 levels indicate disturbed ubiquitin- proteosome system in autism spectrum disorder?

Author

Çetin, İhsan, Tezdiğ, İhsan, Tarakçıoğlu, Mahmut Cem, Kadak, Muhammed Tayyib, Demirel, Ömer Faruk, Erdoğan, Fırat, Doğangün, Burak, and Batman Üniversitesi Sağlık Yüksekokulu Beslenme ve Diyetetik Bölümü

Subjects
Otizm, TDP-43, Autism, UCH-L1, mental disorders, Ubiquitination, Ubikitinlenme
Abstract

Introduction: The mechanism of ubiquitination-related abnormalities causing neural development problems is still unclear. We examined the association between autism and serum transactive response DNAbinding protein-43 (TDP-43) and ubiquitin c-terminal hydrolase-L1 (UCH-L1) levels, both of which are members of the ubiquitinproteosome system. Methods: We measured serum levels of TDP-43 and UCH-L1 in 24 children with autism and 24 healthy children. Childhood Autism Rating Scale (CARS) was used to assess symptom severity at admission. Results: The mean serum TDP-43 and UCH-L1 levels in children with autism spectrum disorder (ASD) were found to decrease compared to healthy controls (p, Amaç: Protein ubikitinlenme ile ilgili bozuklukların nöronal gelişim sorunlarına nasıl yol açtığı açıklanamamıştır. Bu çalışmada, ubikuitin proteozom sistemine üye olan ubikuitin c-terminal hidrolaz-L1 (UCH-L1) ve transaktif yanıtlı DNA-bağlayıcı protein (TDP-43) düzylerinin otizm ile ilişkisi araştırılmıştır. Yöntemler: Bu bağlamda 24 otizm tanılı çocuk ve 24 sağlıklı çocukta serum TDP-43 ve UCH-L1 düzeylerine bakılmıştır. Otizm şiddet derecesi Çocukluk Otizm Derecelendirme Ölçeği (ÇODÖ) ile değerlendirilmiştir. Bulgular: Otizm tanılı çocukların başvuru sırasında ortalama ÇODÖ puanları 48.91 (SD: 5.82) idi. Sağlıklı gruba göre otizmli grupta serum TDP-43 ve Serum UCH-L1 düzeyleri anlamlı olarak düşüktü (sırasıyla 506,21±780,97 ng/L ve 1245,80±996,76 ng/L; 3,08±5,44 ng/mL ve 8,64±6,67 ng/mL; p

Published
2017

36. 9th International Congress on Psychopharmacology & 5th International Symposium on Child and Adolescent Psychopharmacology

Author

Şahmelikoğlu Onur, Özge, primary, Çukurova, Merve, additional, Bağ, Sevda, additional, Yalçın, Suat, additional, Çakır Şen, Cansu, additional, Karşıdağ, Çağatay, additional, Süleyman Can, Serdar, additional, Tuğçe Akçaer, Emine, additional, Taşdelen Kul, Ayşegül, additional, İspir, Mustafa, additional, Bakkal, Osman, additional, Algül, Ayhan, additional, Ebrinç, Servet, additional, Yükselir, Cihad, additional, Zincir, Serkan, additional, Öztürk, Pelin, additional, Karaahmetoğlu, Bülent, additional, Baş, Özlem, additional, Şahmelikoğlu Onur, Özge, additional, Ulukaya, Sema, additional, Soykan, Çağlar, additional, Çayköylü, Ali, additional, Yazar, Neslihan, additional, Başar Kocagöz, Zehra, additional, Özçetin, Adnan, additional, Bahar Ölmez, Safiye, additional, Ataoğlu, Ahmet, additional, Hasan Balcioglu, Yasin, additional, Demir Berkol, Tonguc, additional, Ekim Cevik, Filiz, additional, Oncu, Fatih, additional, Ozgen, Guliz, additional, Demiröz, Dudu, additional, Yardım Özayhan, Hatice, additional, Seven, Hilal, additional, Çağrı Yıldız, Mustafa, additional, Başaran, Recep, additional, Eren, İbrahim, additional, Özlem Canazlar, Elif, additional, Sevinçok, Levent, additional, Doğan, Bilge, additional, Öykü Memiş, Çağdaş, additional, Baran Tanrikulu, Ali, additional, İnanli̇, İkbal, additional, Çağri̇ Yi̇ldi̇z, Mustafa, additional, Şerife Elmas, Tuba, additional, Eren, Ibrahim, additional, Alperen Korkmaz, Şükrü, additional, Pınar Şen, Cansu, additional, Fatih Ceylan, Mehmet, additional, Hesapçıoğlu, Selma Tural, additional, Bakar, Burcu, additional, Tuncer, Can, additional, Yeni Elbay, Rümeysa, additional, Görmez, Aynur, additional, Tokgöz, Yusuf, additional, Bolu, Abdullah, additional, Çelik, Cemil, additional, Uzun, Özcan, additional, Kirlioglu, Simge Seren, additional, Balcioglu, Yasin Hasan, additional, Aydin, Pinar Cetinay, additional, Uğurlu, Mustafa, additional, Uğurlu, Görkem Karakaş, additional, Akçaer, Emine Tuğçe, additional, Can, Serdar Süleyman, additional, Koç, Zuhal, additional, Kapubağlı, Nazlı, additional, Tuncer, Ömer Faruk, additional, Ünlü, Gülsen, additional, Şahin, Esra Kabadayı, additional, Apaydın, Zuhal Koç, additional, Kaymak, Semra Ulusoy, additional, Peker, Oğuz, additional, Özkan, Bedriye, additional, Kılıçoğlu, Ali Güven, additional, Karaçetin, Gül, additional, Yücehan, Zeynep, additional, Elmas, Tuğba Şerife, additional, Yağlı, Nafiye, additional, İlhan, Bilge Çetin, additional, Aker, Derya Adali, additional, Kıvılcım, Yiğit, additional, Solmaz, Mustafa, additional, Kutlu, Yeşim Ruhat, additional, Yeşil, Bahar, additional, Almış, Behice Han, additional, Küçük, Başak, additional, Cerit, Cem, additional, Sarici, Burcu, additional, Kaypak, Ayşe Ceren, additional, Baysak, Erensu, additional, Ergün, Serhat, additional, Yildiz, Mesut, additional, Ibiloglu, Aslihan Okan, additional, Atli, Abdullah, additional, Asoglu, Mehmet, additional, Ozkan, Mustafa, additional, Memik, Nursu Çakın, additional, Ünver, Hatice, additional, Gündoğdu, Özlem Yıldız, additional, Uzun, Necati, additional, Akça, Ömer Faruk, additional, Aral, Gizem, additional, Aykut, Demet Sağlam, additional, Maden, Özgür, additional, Gündoğmuş, İbrahim, additional, Gok, Fulya, additional, Kiraz, Seda, additional, Cipil, Arif, additional, Eroglu, Meliha Zengin, additional, Çiftçi, Elvan, additional, Aslan, Zeynep, additional, Gül, Melike Kevser, additional, Taştepe, Neslihan, additional, Demirci, Esra, additional, Özmen, Sevgi, additional, Doğru, Hicran, additional, Karayağmurlu, Elif, additional, Karayağmurlu, Ali, additional, Göksu, Muhsine, additional, Tügen, Leyla Ezgi, additional, Ayaz, Ayşe Burcu, additional, Arman, Ayşe, additional, Özayhan, Hatice Yardım, additional, Altunova, Deniz, additional, Yıldız, Mustafa Çağrı, additional, Atagün, Murat İlhan, additional, Kul, Ayşegül Taşdelen, additional, Güldaş, Ekrem, additional, Göl, Güler, additional, Savcı, Uğur, additional, Tufan, Ali Evren, additional, Özbek, Seda Yıldırım, additional, Özbek, Süleyman, additional, Uygur, Hilal, additional, Demirel, Başak, additional, Esra Çiçek, İ., additional, Kara, Hüseyin, additional, Balcı, Mehmet Murat, additional, Karaca, Servet, additional, Kuloğlu, Mehmet Murat, additional, Aytaç, Hasan Mervan, additional, Ger, Mehmet Can, additional, İbiloğlu, Aslıhan Okan, additional, Asoğlu, Mehmet, additional, Çakır, Ayşe, additional, Tiryaki, Ahmet, additional, Çelme, Gülşah Güçlü, additional, Boztaş, Mehmet Hamid, additional, Sırmatel, Fatma, additional, Erdogan, Mucahid, additional, Dayan, Cengiz, additional, Atakli, Hayrunisa Dilek, additional, Kartalcı, Gülşen, additional, Yücel, Ebru, additional, Kartalcı, Şükrü, additional, Eroğlu, Meliha Zengin, additional, Çipil, Arif, additional, Çalışkan, Mecit, additional, Çavusoglu, Emine Cengiz, additional, Özdemir, Yusuf Özay, additional, Elmas, Tuba Şerife, additional, Fındıklı, Ebru, additional, Şahin, Berkan, additional, Karabekiroğlu, Koray, additional, Kurt, Mustafa, additional, Memiş, Çağdaş Öykü, additional, Sevinçok, Doğa, additional, Sertdemir, Merve, additional, Ay, Rukiye, additional, Yılmaz, Nevzat, additional, Demirkaya, Sevcan Karakoç, additional, Aksu, Hatice, additional, Gizem Gerçek, Hacer, additional, Karakoç, Gülser, additional, Altıntoprak, Ayşe Ender, additional, Coşkunol, Hakan, additional, Yazici, Ipek Percinel, additional, Utku Yazici, Kemal, additional, Altıntaş, Kevser, additional, Gök, Fulya, additional, Yaylacı, Ferhat, additional, Erkuran, Handan Özek, additional, Eyüboğlu, Murat, additional, Göverti, Diğdem, additional, Yüksel, Rabia Nazik, additional, Bülbül, Alper, additional, Aydemir, Makbule Çiğdem, additional, Göka, Erol, additional, Kınalı, Ilgaz, additional, Hacıoğlu, Münevver Yıldırım, additional, Sarıcı, Burcu, additional, Sayar, Kemal, additional, Doğan, Hatice, additional, Akay, Ömer, additional, Kim, Heecheol, additional, Lee, Hyunjoo, additional, Karagöz, Abdulkadir, additional, Kullakçı, Hakan, additional, Duman, Yasin, additional, Çokünlü, Yusuf, additional, Aydın, Memduha, additional, Tanrıkulu, Ali Baran, additional, Eren, İbrahım, additional, Taner, Hande Ayraler, additional, Sarı, Burcu Akın, additional, Yektaş, Çiğdem, additional, Samurcu, Nuran Demir, additional, Çalışır, Saliha, additional, Ekinci, Özalp, additional, Tan, Muhammet Emin, additional, Kalınlı, Merve, additional, Kıyançiçek, Murat, additional, Küçükdağ, Meltem, additional, Gül, Hasret Karabulut, additional, Uysal, Emel, additional, Arslan, Filiz Civil, additional, Karagüzel, Evrim Özkorumak, additional, Karakök, Burak, additional, Çak, Halime Tuna, additional, Çankaya, Pınar Kızılay, additional, Altun, İlkay Keleş, additional, Abatan, Eren, additional, Çalışkan, Ali Metehan, additional, Çakı, Hatice Kübra, additional, Doğangün, Burak, additional, Kadak, Muhammed Tayyib, additional, Kefeli, Mehmet, additional, Arıcı, Asiye, additional, Altun, Hatice, additional, Acıpayam, Can, additional, Bayhan, Pelin Çon, additional, Sungur, Elif Nurgül, additional, İnci Kenar, Ayşe Nur, additional, Ersoy, Sevde Afife, additional, Gürok, Mehmet Gürkan, additional, Yildiz, Sevler, additional, Korucu, Tuba, additional, Keles, Denizhan Danaci, additional, Atmaca, Murad, additional, Hoşoğlu, Esra, additional, Kılınç, Kübra, additional, Şen, Barış, additional, Örnek, Erdem, additional, Çelebi, Cengiz, additional, Kani, Ayşe Sakallı, additional, Yanartaş, Ömer, additional, Şenkal, Zeynep, additional, Akvardar, Yıldız, additional, Kora, Kaan, additional, Egilmez, Ümran, additional, Kandeğer, Ali, additional, Güler, Özkan, additional, Yazici, Kemal Utku, additional, Kösker, Selcen Dogru, additional, Budak, Elif Ates, additional, Karasin, Zeliha Deveci, additional, Güleken, Mehmet Diyaddin, additional, Celik, Mustafa, additional, Yıldırım, Hande, additional, Güler, Burçin, additional, Veznedaroğlu, Baybars, additional, Lale, Funda, additional, Çak Esen, Halime Tuna, additional, Haliloğlu, Göknur, additional, Ekinci, Nuran, additional, Bilgili, Gamze Özçürümez, additional, Seneger, Volkan, additional, Elbay, Rümeysa Yeni, additional, Işık, Ümit, additional, Aşut, Gonca, additional, Yaylacı, Elif Tatlıdil, additional, Asan, Ömer, additional, Güneş, Serkan, additional, Çiftçi, Ebru, additional, Yaşar, Sehure Azra, additional, İnanlı, İkbal, additional, Sertçelik, Sencan, additional, Avci, Selma Hilal, additional, Yaşar, Alişan Burak, additional, Karatepe, Hasan Turan, additional, Dönmez, Melike, additional, Topçuoğlu, Volkan, additional, Bilgiç, Ayhan, additional, Doğru, Volkan, additional, Bozkurt, Abdullah, additional, Kalyoncu, Tuğba, additional, Çıldır, Deniz Argüz, additional, Beşer, Can, additional, Fiş, Neşe Perdahlı, additional, Ulgar, Şermin Bilgen, additional, Ayaydın, Hamza, additional, Takatak, Hatice, additional, Ayaydin, Hamza, additional, Çobanoğlu, Cansu, additional, Müjdeci, Mahmut, additional, Gümüş, Yusuf Yasin, additional, Akbaş, Betül, additional, Sevgen, Feyza Hatice, additional, Öncü, Fatih, additional, Şahin, Nilfer, additional, Balkan, Damla, additional, Coşkun, Fatma, additional, Yılmaz, Savaş, additional, Çelikkol, Çağla, additional, Emlik, Ganime Dilek, additional, Çaksen, Hüseyin, additional, Arslan, Derya, additional, Arısoy, Özden, additional, Şair, Ahmet, additional, Şair, Yaşan Bilge, additional, Sarı, Dilek, additional, Ispir, Mustafa, additional, Algul, Ayhan, additional, Ölmeztoprak, Vuslat Kara, additional, Zayman, Esra Porgalı, additional, Ünal, Süheyla, additional, Öztürk, Ali Hakan, additional, Karabucak, Başak, additional, Çengel Kültür, Ebru Sadriye, additional, Çak Esen, Tuna Halime, additional, Özaktaç, İpek Fatma, additional, Altın, Murat, additional, Sarıdoğan, Ayşe Sena, additional, Buluş, Eser, additional, Güneş, Sevilay, additional, Koyuncu, Zehra, additional, Bingöl, Rahime Hülya, additional, Uzgel, Mine, additional, Ayas, Selahattin, additional, Kıvrak, Yüksel, additional, Şahbal, Yiğit, additional, Kocagöz, Kübra, additional, Kutlu, Gamze, additional, Baz, Ali, additional, Cansız, Mehmet Akif, additional, Kalyoncu, Tugba, additional, Sağlam, Ebru, additional, Önen, Özlem, additional, Kutlu, Ayşe, additional, Aşık, Ecenur Aydın, additional, Sapmaz, Şermin Yalın, additional, Erermiş, Serpil, additional, Şişmanlar, Şahika Gülen, additional, Karka, İsmail, additional, Kilicaslan, Fethiye, additional, Hürmeydan, Ceren Enüstün, additional, Onur, Özge Şahmelikoğlu, additional, Onur, Ozge Sahmelikoğlu, additional, Sarı, Didem Nagehan, additional, Kılıç, Bahar, additional, Kurt, Elif Merve, additional, Ak, İsmail, additional, Şevik, Ali Emre, additional, Yalçın, Ayşe Dilara, additional, Tural, Ümit, additional, Yaşar, Hilmi, additional, Korkmaz, Şükrü Alperen, additional, Karaaslan, Münir, additional, Kizilağaç, Fatih, additional, Öznur, Taner, additional, Baran Tanri̇kulu, Ali̇, additional, Yildiz, Mustafa Çağri, additional, İnanli, İkbal, additional, Öztürk, Seher Serez, additional, Özbek, Seda, additional, Çiçek, İsmet Esra, additional, Karlıdağ, Rıfat, additional, Akan, Mustafa, additional, İnce, Lara Utku, additional, Reyhani, İsmail, additional, Tetik, Dilek Çağlar, additional, Büyükaslan, Ayşe, additional, Yılanlı, Musa, additional, Cesur, Ender, additional, Belger, Fatma, additional, Başay, Bürge Kabukçu, additional, Şen, Cansu Pinar, additional, Ceylan, Mehmet Fatih, additional, Hesapcioglu, Selma Tural, additional, Teksin, Gülşen, additional, Kupeli, Nese Yorguner, additional, Ergun, Serhat, additional, Atlı, Abdullah, additional, Okan İbiloğlu, Aslıhan, additional, Akıl, Öznur, additional, and İbilioğlu, Aslıhan Okan, additional

Published
2017
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38. Neurocognitive Deficits in Euthymic Bipolar Patients

Author

DEMİREL, Ayşegül, DEMİREL, Ömer Faruk, KADAK, Muhammed Tayyib, and DURAN, Alaattin

Subjects
Bipolar bozukluk,nörobilişsel defisit,endofenotip, Bipolar disorder,neurocognitive deficits,endophenotype, mental disorders
Abstract

Neurocognitive deficits detected in bipolar patients have a negative influence on clinical course and severity. We reviewed studies on neurocognitive deficits in euthymic bipolar subjects and their possible neuroanatomical correlates. We also examined studies suggesting deficits seen in euthymic patients may be endophenotypes of the disorder. Results of the studies in euthymic patients and their healthy relatives indicate that have cognitive dysfunctions especially of verbal memory, learning and executive domains, which were found to be related to prefrontal cortex and temporo-limbic circuitry. Longitudinal studies investigating heritability of cognitive impairment in bipolar disorder and its relation with brain connectivity and epigenetic mechanisms are needed. Keywords: Bipolar disorder, neurocognitive deficit, endophenotype, Nörobilişsel defisitlerin bipolar bozukluğun seyri ve ciddiyeti üzerinde belirle-yici olduğu bilinmektedir. Bu derlemede ötimik bipolar hastalarda nörobilişsel defisit varlığını, bu defisitlerle bipolar hastalarda saptanan nöroanatomik lezyonların ilişkisi ve bu hastalarda saptanan bazı defisitlerin bir endofenotip olabileceği ile ilgili çalışmaları gözden geçirilmiştir. Çalışmalar ötimik hastalarda ve sağlıklı aile bireylerinde prefrontal korteks, temporo-limbik döngü ile ilişkili bulunan sözel bellek, öğrenme ve yürütücü fonksiyon alanlarında defisit gösterdiklerini teyit etmiştir. Ötimik hastalarda saptanan bilişsel defisitlerin genetik temellerini, bipolar hastalarda nöroanatomik tutu-lumla olan ilişkisini ve epigenetik mekanizmaların hastalık sürecine olası etkilerini araştırmaya yönelik çalışmalara ihtiyaç vardır.

Published
2014

44. Postpartum depression in mothers of babies with infantile colic

Author

Erdoǧan, Fırat, Kadak, Muhammed Tayyib, Kartal, Vural, Arıcı, Neslihan, Eliaçık, Mustafa, Demirel, Ömer Faruk, and İpek, İlke Özahi

Subjects
Infant Mental Health, Postpartum Depresyon, Bebek Ruh Sağlığı, Postpartum Depression, İnfantil Kolik, Infantile Colic
Abstract

Amaç: Doğum sonrası depresyon, hem anne hem de çocukta birçok soruna yol açarak anne-çocuk ilişkisini, annenin bakım verme ve ebeveynlik becerilerini olumsuz etkiler. Erken çocukluk döneminde görülen sorunlardan biri de infantil koliktir (İK). Bu çalışmamızda İK ile postpartum depresyon (PPD) arasındaki ilişki araştırılmıştır. Yöntem: Çalışmamızda 3 aylıktan küçük bebeklerin anneleri (n=102) Edinburgh Doğum Sonrası Depresyon Ölçeği (EDSDÖ) ile değerlendirilmiştir. Bulgular: İK olan bebeklerin (n=55) annelerinde EDSDÖ skor ortalaması (12,7±4,8) İK olmayanlara (n=47) göre (8,44±5,62) anlamlı derecede yüksek bulunmuştur (p

Published
2014

45. Evaluation of the Relationship Between Attention Deficit Hyperactivity Disorder Symptoms and Chronotype.

Author

TARAKÇIOĞLU, Mahmut Gem, KADAK, Muhammed Tayyib, GÜRBÜZ, Gözde AKKIN, POYRAZ, Burç Çağrı, ERDOĞAN, Fırat, and AKSOY, Umut Mert

Subjects
*HYPOTHESIS, *AGE distribution, *ATTENTION-deficit hyperactivity disorder, *QUESTIONNAIRES, *SCHOOLS, *SEX distribution, *SLEEP disorders, *BEHAVIOR disorders
Abstract

Introduction: The aim of the study is to investigate the relationship between circadian characteristics and behavioral problems in children with Attention Deficit Hyperactivity Disorder (ADHD) (n=53), and to compare this group with healthy controls (n=38). Method: Fifty-three medication-free children with ADHD, aged 6-12 years, and 38 healthy children, age and sex matched, participated. Parents completed the Conners' Parent Rating Scale-Revised, the Children's Chronotype Questionnaire (CCTQ), and the Children's Sleep Habits Questionnaire (CSHQ) to assess sleep variables. Results: ADHD children had more sleep-onset problems and parasomnias (in CSHQ) compared to healthy controls. However, circadian preferences did not differ between the groups in CCTQ scores. Another important finding was a mild correlation between parasomnia, bedtime on schooldays, and ADHD symptoms. Conclusion: Our study showed that children with ADHD showed more resistance to going to bed than did controls on school days. However, in contrast to our hypothesis, morningness/eveningness preference did not differ from controls in ADHD children. [ABSTRACT FROM AUTHOR]

Published
2018
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46. Relation between personality,recognition of emotional face expression and broad autism phenotype in parents of children with autism spectrum disorder

Author

Kadak, Muhammed Tayyib, Demir, Türkay, and Çocuk Ruh Sağlığı ve Hastalıkları Ana Bilim Dalı

Subjects
Psychiatry, Phenotype, Face, Face recognition, Autistic disorder, Children, Psikiyatri
Abstract

Amaç: Otistik spektrum bozuklukları, erken çocukluk çağında başlayan toplumsal etkileşim ve dil gelişiminde geriliklerle beraber basmakalıp davranışların görüldüğü bir nöropsikiyatrik bozukluk grubudur. Aile ve ikiz çalışmaları, genel nüfusa göre otistik bireylerin yakınlarında otizmin çekirdek belirtilerine niteliksel olarak benzeyen ancak daha geniş olarak tanımlanmış davranışsal fenotiplerin bulunabileceğini göstermiştir. Yüz ifadelerini tanıma kusurları otistik spektrum bozukluğu olanlarda bildirilmiştir. Yüz ifadelerini tanıma becerilerini araştıran çalışmalarda otistiklerin anababalarının sağlıklı kontrollere göre daha başarısız oldukları bildirilmiştir. Bu çalışmada geniş otizm fenotipi ile yüz ifadelerini tanıma kusuru arasındaki ilişki araştırılacaktır.Yöntem: Çalışmaya DSM-IV'e göre otistik spektrum bozukluğu tanısı almış 36 çocuğun anababası ile kontrol grubu olarak 19 çocuğun anababası alınmıştır. Çalışmada geniş otizm fenotipi özellikleri Otizm-Spektrum Anketi (OSA) ve Geniş Otizm Fenotipi Ölçeği (GOFÖ) ile, yüz ifadeleri ise Yüz İfadeleri Tanıma Testi ile değerlendirilmiştir. Çalışmada iki grup arasındaki ölçek puan farkları Student's t testi ile değerlendirilmiştir. Bulgular ANOVA ve ANCOVA ile karşılaştırılmıştır.Bulgular: OSA Sosyal beceri alt-ölçeği ortalamaları açısından iki grup karşılaştırıldığında sosyal beceri puanları olgu grubunda daha yüksek saptanmıştır (p< 0.05). Grupların GOFÖ soğukluk alt ölçeği puan ortalamaları karşılaştırıldığında soğukluk puanları olgu grubunda daha yüksek bulunmuştur (p< 0.05). Yüz ifadeleri doğruluk oranları karşılaştırıldığında olgu grubu nötr ifadeleri tanımada kontrol grubuna göre anlamlı olarak daha kötü performans göstermiştir.Sonuç: OSB tanılı çocukların anababalarında sosyal iletişim alanında GOF özelliklerinin görülme riski artmaktadır. Ayrıca otistiklerin anababalarında muğlak veya nötr ifadeleri tanıma sorunları otistik olmayan çocukların anababalarına göre daha fazla fazladır.Anahtar kelimeler: otizm, geniş otizm fenotipi, yüz ifadelerini tanıma, anababa, çocuk Objective: Autism spectrum disorder is a neuropsychiatric disorder defined by the presence of social deficits, communication abnormalities, stereotyped or repetitive behaviors. A number of family and twin studies have suggested that a behavioral phenotype that is qualitatively similar to but more broadly defined than that which defines autism occurs more commonly in relatives of autistic individuals than in the general population. Deficits of emotional face expression was reported in individal with autism spectrum disorder. In recent studies it was shown that parents of autism spectrum disorder patients revealed worse performance with emotional face expression task. In this research, relation between broad autism phenotype and impairment of facial expression of emotion will be studied.Method: Seventy-two parents who had a child with a diagnosis of DSM-IV Autism Spectrum Disorder and thirty-eight parents who had a typically developing child were included in this study. The parents were subsequently assessed for broad autism phenotype by Autism-Spectrum Quotient (ASQ) and Broad Autism Phenotype Questianaire (BAPQ) and for impairment in the recognition of facial expressions by Emotion Recognition Test. Student?s t-test was used to evaluate the differences between the two groups. Results had compared by using ANOVA and ANCOVA.Result: When AQ component `Social skills? results were examined, the social skill scores of parents with autistic children was found signi ? cantly higher (p

Published
2011

49. Use of social network sites among depressed adolescents.

Author

Akkın Gürbüz, Hatice Gözde, Demir, Türkay, Gökalp Özcan, Burcu, Kadak, Muhammed Tayyib, and Poyraz, Burç Çağrı

Subjects
CHI-squared test, DEPRESSION in adolescence, FISHER exact test, PROBABILITY theory, PSYCHOLOGICAL tests, RESEARCH funding, WORLD Wide Web, SOCIAL media, DATA analysis software, MANN Whitney U Test, ADOLESCENCE
Abstract

Social network sites (SNSs) are relatively new phenomena, and the relationship between SNSs and psychopathology remains unclear. The purpose of this study was to evaluate the type of SNSs depressed adolescents use and the incidence of depressive disclosure on SNSs among them. The study was designed to be cross-sectional. The sample consisted of 53 adolescents diagnosed with depressive disorder, as confirmed by K-SADS-PL, and 55 non-depressed adolescents. The Children’s Depression Inventory, Social Anxiety Scale and Social Network Use Questionnaire were administered. The primary finding was that the amount of time spent on the Internet and on SNSs was significantly higher among depressed adolescents than non-depressed adolescents. Additionally, depressed adolescents reported significantly higher disclosure of anhedonia, worthlessness, guilt, loss of concentration, irritability and thoughts of suicide on SNSs. The intensity of the depression sharing was significantly higher in the depressed group. Depressed young people use social networks to express their symptoms. Adolescents’ disclosure on social networks may be able to guide relatives, friends and mental health professionals. [ABSTRACT FROM PUBLISHER]

Published
2017
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50. Heterogeneity of subclinical autistic traits among parents of children with autism spectrum disorder: Identifying the broader autism phenotype with a data-driven method.

Author

Bora, Emre, Aydın, Aydan, Saraç, Tuğba, Kadak, Muhammed Tayyib, and Köse, Sezen

Abstract

Clinical diagnosis of autism spectrum disorder (ASD) can be conceptualized as the extreme end of the distribution of subclinical autistic traits related to genetic susceptibility factors (broad autism phenotype (BAP)) in the general population. Subclinical autistic traits are significantly more common among unaffected first-degree relatives of probands with autism. However, there is a significant heterogeneity of autistic traits in family members of individuals with ASD and severity of autistic traits are not significantly different from controls in the majority of these relatives. The current study investigated the heterogeneity of autistic traits using latent class analysis (LCA) of the Autism Spectrum Quotient (AQ) ratings of 673 parents of children with ASD and 147 parents of typically developing children. Two distinct subgroups, including a "low-scoring" and a "high-scorer (BAP)" groups, were found. In comparison to control parents, a significantly larger proportion (21.1% vs. 7.5%) of parents of ASD were members of BAP group. Communication subscale made a distinctive contribution to the separation of high and low-scoring groups ( d = 2.77). Further studies investigating neurobiological and genetic biomarkers and stability of these two subgroups over time are important for understanding the nature of autistic traits in the general population. Autism Res 2017, 10: 321-326. © 2016 International Society for Autism Research, Wiley Periodicals, Inc. [ABSTRACT FROM AUTHOR]

Published
2017
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