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1. Neurological hospitalisations in childhood cancer survivors treated before 2001: findings from the French Childhood Cancer Survivor Study cohort

Author

Rajaonera, David, Bejarano-Quisoboni, Daniel, Grill, Jacques, Allodji, Rodrigue S., Pelletier-Fleury, Nathalie, Journy, Neige, Boussac, Marjorie, Doz, François, Vu-Bezin, Giao, Zidane, Monia, Schwartz, Boris, Haddy, Nadia, Bolle, Stéphanie, El-Fayech, Chiraz, Dufour, Christelle, Diallo, Ibrahima, Schleiermacher, Gudrun, Fresneau, Brice, and de Vathaire, Florent

Published
2024
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2. Risk of subsequent gliomas and meningiomas among 69,460 5-year survivors of childhood and adolescent cancer in Europe: the PanCareSurFup study

Author

Heymer, Emma J., Hawkins, Michael M., Winter, David L., Teepen, Jop C., Sunguc, Ceren, Ronckers, Cécile M., Allodji, Rodrigue S., Alessi, Daniela, Sugden, Elaine, Belle, Fabiën N., Bagnasco, Francesca, Byrne, Julianne, Bárdi, Edit, Garwicz, Stanislaw, Grabow, Desiree, Jankovic, Momcilo, Kaatsch, Peter, Kaiser, Melanie, Michel, Gisela, Schindera, Christina, Haddy, Nadia, Journy, Neige, Česen Mazić, Maja, Skinner, Roderick, Kok, Judith L., Gunnes, Maria W., Wiebe, Thomas, Sacerdote, Carlotta, Maule, Milena M., Terenziani, Monica, Jakab, Zsuzsanna, Winther, Jeanette F., Lähteenmäki, Päivi M., Zadravec Zaletel, Lorna, Haupt, Riccardo, Kuehni, Claudia E., Kremer, Leontien C., de Vathaire, Florent, Hjorth, Lars, and Reulen, Raoul C.

Published
2024
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3. Risk of hematological malignancies from CT radiation exposure in children, adolescents and young adults

Author

Bosch de Basea Gomez, Magda, Thierry-Chef, Isabelle, Harbron, Richard, Hauptmann, Michael, Byrnes, Graham, Bernier, Maria-Odile, Le Cornet, Lucian, Dabin, Jérémie, Ferro, Gilles, Istad, Tore S., Jahnen, Andreas, Lee, Choonsik, Maccia, Carlo, Malchair, Françoise, Olerud, Hilde, Simon, Steven L., Figuerola, Jordi, Peiro, Anna, Engels, Hilde, Johansen, Christoffer, Blettner, Maria, Kaijser, Magnus, Kjaerheim, Kristina, Berrington de Gonzalez, Amy, Journy, Neige, Meulepas, Johanna M., Moissonnier, Monika, Nordenskjold, Arvid, Pokora, Roman, Ronckers, Cecile, Schüz, Joachim, Kesminiene, Ausrele, and Cardis, Elisabeth

Published
2023
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4. Radiation Doses Received by Major Organs at Risk in Children and Young Adolescents Treated for Cancer with External Beam Radiation Therapy: A Large-scale Study from 12 European Countries

Author

Diallo, Ibrahima, Allodji, Rodrigue S., Veres, Cristina, Bolle, Stéphanie, Llanas, Damien, Ezzouhri, Safaa, Zrafi, Wael, Debiche, Ghazi, Souchard, Vincent, Fauchery, Romain, Haddy, Nadia, Journy, Neige, Demoor-Goldschmidt, Charlotte, Winter, David L., Hjorth, Lars, Wiebe, Thomas, Haupt, Riccardo, Robert, Charlotte, Kremer, Leontien, Bardi, Edit, Sacerdote, Carlotta, Terenziani, Monica, Kuehni, Claudia E., Schindera, Christina, Skinner, Roderick, Winther, Jeanette Falck, Lähteenmäki, Päivi, Byrn, Julianne, Jakab, Zsuzsanna, Cardis, Elisabeth, Pasqual, Elisa, Tapio, Soile, Baatout, Sarah, Atkinson, Mike, Benotmane, Mohammed Abderrafi, Sugden, Elaine, Zaletel, Lorna Zadravec, Ronckers, Cecile, Reulen, Raoul C., Hawkins, Mike M., and de Vathaire, Florent

Published
2024
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5. Deep-Learning for Rapid Estimation of the Out-of-Field Dose in External Beam Photon Radiation Therapy – A Proof of Concept

Author

Benzazon, Nathan, Carré, Alexandre, de Kermenguy, François, Niyoteka, Stéphane, Maury, Pauline, Colnot, Julie, M'hamdi, Meissane, Aichi, Mohammed El, Veres, Cristina, Allodji, Rodrigue, de Vathaire, Florent, Sarrut, David, Journy, Neige, Alapetite, Claire, Grégoire, Vincent, Deutsch, Eric, Diallo, Ibrahima, and Robert, Charlotte

Published
2024
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6. Surveillance after childhood cancer: are survivors with an increased risk for cardiomyopathy regularly followed-up?

Author

Bougas, Nicolas, Allodji, Rodrigue S., Fayech, Chiraz, Haddy, Nadia, Mansouri, Imene, Journy, Neige, Demoor, Charlotte, Allard, Julie, Thebault, Eric, Surun, Aurore, Pacquement, Hélène, Pluchart, Claire, Bondiau, Pierre-Yves, Berchery, Delphine, Laprie, Anne, Boussac, Marjorie, Jackson, Angela, Souchard, Vincent, Vu-Bezin, Giao, Dufour, Christelle, Valteau-Couanet, Dominique, de Vathaire, Florent, Fresneau, Brice, and Dumas, Agnès

Published
2023
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7. Life years lost by childhood cancer treatment and health related late effects among childhood cancer survivors

Author

Charrier, Thibaud, Haddy, Nadia, Fresneau, Brice, Schwartz, Boris, Journy, Neige, Demoor-Goldschmidt, Charlotte, Diallo, Ibrahima, Aerts, Isabelle, Doz, François, Souchard, Vincent, Vu-Bezin, Giao, Laprie, Anne, Lemler, Sarah, Letort, Véronique, Rubino, Carole, Kamary, Kaniav, Aba, Naïla Myriam, Ducos, Claire, Locquet, Médéa, Vathaire, Florent de, Allodji, Rodrigue S., and Latouche, Aurélien

Published
2024
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9. Increased Cardiac Risk After a Second Malignant Neoplasm Among Childhood Cancer Survivors: A FCCSS Study

Author

Charrier, Thibaud, Haddy, Nadia, Schwartz, Boris, Journy, Neige, Fresneau, Brice, Demoor-Goldschmidt, Charlotte, Diallo, Ibrahima, Surun, Aurore, Aerts, Isabelle, Doz, François, Souchard, Vincent, Vu-Bezin, Giao, Laprie, Anne, Lemler, Sarah, Letort, Véronique, Rubino, Carole, Chounta, Stéfania, de Vathaire, Florent, Latouche, Aurélien, and Allodji, Rodrigue S.

Published
2023
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11. Brain cancer after radiation exposure from CT examinations of children and young adults: results from the EPI-CT cohort study

Author

Hauptmann, Michael, Byrnes, Graham, Cardis, Elisabeth, Bernier, Marie-Odile, Blettner, Maria, Dabin, Jérémie, Engels, Hilde, Istad, Tore S, Johansen, Christoffer, Kaijser, Magnus, Kjaerheim, Kristina, Journy, Neige, Meulepas, Johanna M, Moissonnier, Monika, Ronckers, Cecile, Thierry-Chef, Isabelle, Le Cornet, Lucian, Jahnen, Andreas, Pokora, Roman, Bosch de Basea, Magda, Figuerola, Jordi, Maccia, Carlo, Nordenskjold, Arvid, Harbron, Richard W, Lee, Choonsik, Simon, Steven L, Berrington de Gonzalez, Amy, Schüz, Joachim, and Kesminiene, Ausrele

Published
2023
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12. Long-term hospitalisations in survivors of paediatric solid tumours in France

Author

Bejarano-Quisoboni, Daniel, Pelletier-Fleury, Nathalie, Allodji, Rodrigue S., Fresneau, Brice, Boussac, Majorie, Pacquement, Hélène, Doz, François, Berchery, Delphine, Pluchart, Claire, Bondiau, Piere-Yves, Nys, Julie, Jackson, Angela, Demoor-Goldschmidt, Charlotte, Dumas, Agnes, Thomas-Teinturier, Cécile, Schwartz, Boris, Journy, Neige, Rubino, Carole, Vu-Bezin, Giao, Valteau-Couanet, Dominique, El-Fayech, Chiraz, Dufour, Christelle, Haddy, Nadia, and de Vathaire, Florent

Published
2022
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13. Deep-learning for rapid estimation of the out-of-field dose in external beam photon radiotherapy – A proof of concept

Author

Benzazon, Nathan, primary, Carré, Alexandre, additional, de Kermenguy, François, additional, Niyoteka, Stéphane, additional, Maury, Pauline, additional, Colnot, Julie, additional, M'hamdi, Meissane, additional, Aichi, Mohammed El, additional, Veres, Cristina, additional, Allodji, Rodrigue, additional, Vathaire, Florent de, additional, Sarrut, David, additional, Journy, Neige, additional, Alapetite, Claire, additional, Grégoire, Vincent, additional, Deutsch, Eric, additional, Diallo, Ibrahima, additional, and Robert, Charlotte, additional

Published
2024
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14. Long-term follow-up of high-risk neuroblastoma survivors treated with high-dose chemotherapy and stem cell transplantation rescue

Author

Haghiri, Sandrine, Fayech, Chiraz, Mansouri, Imène, Dufour, Christelle, Pasqualini, Claudia, Bolle, Stéphanie, Rivollet, Sophie, Dumas, Agnès, Boumaraf, Amel, Belhout, Amel, Journy, Neige, Souchard, Vincent, Vu-Bezin, Giao, Veres, Cristina, Haddy, Nadia, De Vathaire, Florent, Valteau-Couanet, Dominique, and Fresneau, Brice

Published
2021
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15. Towards a European prospective data registry for particle therapy

Author

Grau, Cai, Dasu, Alexandru, Troost, Esther G.C., Haustermans, Karin, Weber, Damien C., Langendijk, Johannes A., Gregoire, Vincent, Orlandi, Ester, Thariat, Juliette, Journy, Neige, Chaikh, Abdulhamid, Isambert, Aurelie, Jereczek-Fossa, Barbara Alicja, Vaniqui, Ana, Vitek, Pavel, Kopec, Renata, Fijten, Rianne, Luetgendorf-Caucig, Carola, Olko, Pawel, Grau, Cai, Dasu, Alexandru, Troost, Esther G.C., Haustermans, Karin, Weber, Damien C., Langendijk, Johannes A., Gregoire, Vincent, Orlandi, Ester, Thariat, Juliette, Journy, Neige, Chaikh, Abdulhamid, Isambert, Aurelie, Jereczek-Fossa, Barbara Alicja, Vaniqui, Ana, Vitek, Pavel, Kopec, Renata, Fijten, Rianne, Luetgendorf-Caucig, Carola, and Olko, Pawel

Abstract

The evidence for the value of particle therapy (PT) is still sparse. While randomized trials remain a cornerstone for robust comparisons with photon-based radiotherapy, data registries collecting real-world data can play a crucial role in building evidence for new developments. This Perspective describes how the European Particle Therapy Network (EPTN) is actively working on establishing a prospective data registry encompassing all patients undergoing PT in European centers. Several obstacles and hurdles are discussed, for instance harmonization of nomenclature and structure of technical and dosimetric data and data protection issues. A preferred approach is the adoption of a federated data registry model with transparent and agile governance to meet European requirements for data protection, transfer, and processing. Funding of the registry, especially for operation after the initial setup process, remains a major challenge.

Published
2024
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16. Assessing late outcomes of advances in radiotherapy for paediatric cancers: Study protocol of the “HARMONIC-RT” European registry (NCT 04746729)

Author

Journy, Neige, primary, Bolle, Stéphanie, additional, Brualla, Lorenzo, additional, Dumas, Agnès, additional, Fresneau, Brice, additional, Haddy, Nadia, additional, Haghdoost, Siamak, additional, Haustermans, Karin, additional, Jackson, Angela, additional, Karabegovic, Sanja, additional, Lassen–Ramshad, Yasmin, additional, Thariat, Juliette, additional, Wette, Martina Roxanne, additional, Botzenhardt, Suzan, additional, De Wit, Inge, additional, Demoor-Goldschmidt, Charlotte, additional, Christiaens, Melissa, additional, Høyer, Morten, additional, Isebaert, Sofie, additional, Jacobs, Sandra, additional, Henriksen, Louise Tram, additional, Maduro, John H., additional, Ronckers, Cecile, additional, Steinmeier, Theresa, additional, Uyttebroeck, Anne, additional, Van Beek, Karen, additional, Walsh, Linda, additional, Thierry-Chef, Isabelle, additional, and Timmermann, Beate, additional

Published
2024
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17. Health effects of ionising radiation in paediatrics undergoing either cardiac fluoroscopy or modern radiotherapy (The HARMONIC project)

Author

Thierry-Chef Isabelle, Timmermann Beate, Journy Neige, Bernier Marie-Odile, McNally Richard, Dabin Jérémie, Brualla Lorenzo, Haghdoost Siamak, Sarukhan Adelaida, Haustermans Karin, De Wit Inge, Isebaert Sofie, Lassen-Ramshad Yasmin, Tram Henriksen Louise, Høyer Morten, Toussaint Laura, Boissonnat Guillaume, Thariat Juliette, Demoor-Goldschmidt Charlotte, Haddy Nadia, Bolle Stéphanie, Fresneau Brice, Belhout Amel, Dreger Steffen, Zeeb Hajo, Grazia Andreassi Maria, Campolo Jonica, Picano Eugenio, Jahnen Andreas, Ronckers Cécile, Maduro John H., Kjaerheim Kristina, Døhlen Gaute, Robsahm Trude Eid, Olerud Hilde M., Thevathas Utheya Salini, Afroz Susmita, Helge Østerås Bjørn, Schneider Uwe, Walsh Linda, Dumas Agnès, Jackson Angéla, Rage Estelle, De Saint-Hubert Marijke, Hardy Richard, Bäumer Christian, Steinmeier Theresa, Botzenhardt Suzan, Wette Martina, Ortiz Rodney, and Chumak Vadim

Subjects
Nuclear engineering. Atomic power, TK9001-9401
Abstract

The use of ionising radiation (IR) for medical diagnosis and treatment procedures has had a major impact on the survival of paediatric patients. Although the benefits of these techniques lead to efficient health care, evaluation of potential associated long-term health effects is required. HARMONIC aims to better understand the increased risk of cancer and non-cancer effects after exposure to medical IR in children with cancer treated with modern external beam radiotherapy (EBRT) – radiation energy in MeV range – and in children with cardiac defects diagnosed and treated with cardiac fluoroscopy procedures (CFP) – radiation energy in keV range. The project investigates, among survivors of paediatric cancer, potential endocrine dysfunction, cardiovascular and neurovascular damage, health-related quality of life and second (and subsequent) primary cancer (SPC). The cardiac component builds a pooled cohort of approximately 90 000 paediatric patients who underwent CFP during childhood and adolescence to investigate cancer risk following exposure to IR and explore the potential effects of conditions predisposing to cancer. HARMONIC develops software tools to allow dose reconstruction in both EBRT and CFP to enable epidemiological investigations and future optimisation of treatments. With the creation of a biobank of blood and saliva samples, HARMONIC aims to provide a mechanistic understanding of radiation-induced adverse health effects and identify potential biomarkers that can predict these effects.

Published
2023
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18. Patterns of proton therapy use in pediatric cancer management in 2016: An international survey

Author

Journy, Neige, Indelicato, Daniel J., Withrow, Diana R., Akimoto, Tetsuo, Alapetite, Claire, Araya, Masayuki, Chang, Andrew, Chang, John Han-Chih, Chon, Brian, Confer, Michael E., Demizu, Yusuke, Dendale, Rémi, Doyen, Jérôme, Ermoian, Ralph, Gurtner, Kristin, Hill-Kayser, Christine, Iwata, Hiromitsu, Kim, Joo-Young, Kwok, Young, Laack, Nadia N., Lee, Choonsik, Lim, Do Hoon, Loredo, Lilia, Mangona, Victor S., Mansur, David B., Murakami, Masao, Murayama, Shigeyuki, Ogino, Takashi, Ondrová, Barbora, Parikh, Rahul R., Paulino, Arnold C., Perkins, Stephanie, Ramakrishna, Naren R., Richter, Ronald, Rombi, Barbara, Shibata, Satoshi, Shimizu, Shinichi, Timmermann, Beate, Vern-Gross, Tamara, Wang, Chiachien J., Weber, Damien C., Wilkinson, John Ben, Witt Nyström, Petra, Yock, Torunn I., Kleinerman, Ruth A., and Berrington de Gonzalez, Amy

Published
2019
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20. Complete patient exposure during paediatric brain cancer treatment for photon and proton therapy techniques including imaging procedures

Author

De Saint-Hubert, Marijke, primary, Boissonnat, Guillaume, additional, Schneider, Uwe, additional, Bäumer, Christian, additional, Verbeek, Nico, additional, Esser, Johannes, additional, Wulff, Jörg, additional, Stuckmann, Florian, additional, Suesselbeck, Finja, additional, Nabha, Racell, additional, Dabin, Jérémie, additional, Vasi, Fabiano, additional, Radonic, Stephan, additional, Rodriguez, Miguel, additional, Simon, Anne Catherine, additional, Journy, Neige, additional, Timmermann, Beate, additional, Thierry-Chef, Isabelle, additional, and Brualla, Lorenzo, additional

Published
2023
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24. Pooled Analysis of Meningioma Risk Following Treatment for Childhood Cancer

Author

Withrow, Diana R., primary, Anderson, Harald, additional, Armstrong, Gregory T., additional, Hawkins, Michael, additional, Journy, Neige, additional, Neglia, Joseph P., additional, de Vathaire, Florent, additional, Tucker, Margaret A., additional, Inskip, Peter D., additional, Brenner, Alina V., additional, Stovall, Marilyn A., additional, Diallo, Ibrahima, additional, Berrington de Gonzalez, Amy, additional, and Veiga, Lene H. S., additional

Published
2022
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25. Individual radiation exposure from computed tomography: a survey of paediatric practice in French university hospitals, 2010–2013

Author

Journy, Neige M. Y., Dreuil, Serge, Boddaert, Nathalie, Chateil, Jean-François, Defez, Didier, Ducou-le-Pointe, Hubert, Garcier, Jean-Marc, Guersen, Joël, Habib Geryes, Bouchra, Jahnen, Andreas, Lee, Choonsik, Payen-de-la-Garanderie, Jacqueline, Pracros, Jean-Pierre, Sirinelli, Dominique, Thierry-chef, Isabelle, and Bernier, Marie-Odile

Published
2017
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27. Thyroid dysfunction and breast cancer risk among women in the UK Biobank cohort

Author

Tran, Thi-Van-Trinh, Maringe, Camille, Benitez Majano, Sara, Rachet, Bernard, Boutron-Ruault, Marie-Christine, and Journy, Neige

Subjects
Adult, endocrine system, endocrine system diseases, Age Factors, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Breast Neoplasms, Middle Aged, United Kingdom, Cohort Studies, breast cancer, Risk Factors, Confidence Intervals, Prevalence, cohort study, incidence, Humans, hyperthyroidism, Female, hypothyroidism, Cancer Prevention, RC254-282, Original Research, Aged, Proportional Hazards Models
Abstract

This study aimed to evaluate the association between thyroid dysfunction and breast cancer risk. We included 239,436 females of the UK Biobank cohort. Information on thyroid dysfunction, personal and family medical history, medications, reproductive factors, lifestyle, and socioeconomic characteristics was retrieved from baseline self‐reported data and hospital inpatient databases. Breast cancer diagnoses were identified through population‐based registries. We computed Cox models to estimate hazard ratios (HRs) of breast cancer incidence for thyroid dysfunction diagnosis and treatments, and examined potential confounding and effect modification by comorbidities and breast cancer risk factors. In our study, 3,227 (1.3%) and 20,762 (8.7%) women had hyper‐ and hypothyroidism prior to the baseline. During a median follow‐up of 7.1 years, 5,326 (2.2%) women developed breast cancer. Compared to no thyroid dysfunction, there was no association between hypothyroidism and breast cancer risk overall (HR = 0.93, 95% confidence interval (CI): 0.84–1.02, 442 cases), but we found a decreased risk more than 10 years after hypothyroidism diagnosis (HR=0.85, 95%CI 0.74–0.97, 226 cases). There was no association with hyperthyroidism overall (HR=1.08, 95%CI 0.86–1.35, 79 cases) but breast cancer risk was elevated among women with treated hyperthyroidism (HR=1.38, 95%CI: 1.03–1.86, 44 cases) or aged 60 years or more at hyperthyroidism diagnosis (HR=1.74, 95%CI: 1.01–3.00, 113 cases), and 5–10 years after hyperthyroidism diagnosis (HR=1.58, 95%CI: 1.06–2.33, 25 cases). In conclusion, breast cancer risk was reduced long after hypothyroidism diagnosis, but increased among women with treated hyperthyroidism. Future studies are needed to determine whether the higher breast cancer risk observed among treated hyperthyroidism could be explained by hyperthyroidism severity, type of treatment or aetiology., In this study, we included 239,436 women in the general population‐based UK Biobank cohort to investigate the association between thyroid dysfunction and breast cancer risk. Our study suggested there was no association between hyper‐ and hypothyroidism in overall and breast cancer risk. However, among treated hyperthyroidism, we found a higher breast cancer risk, which could be explained by hyperthyroidism severity or aetiology.

Published
2021

28. Risk factors for obesity in adulthood among survivors of childhood cancer.

Author

Delacourt, Laurène, Allodji, Rodrigue, Chappat, Juliette, Haddy, Nadia, El‐Fayech, Chiraz, Demoor‐Goldschmidt, Charlotte, Journy, Neige, Bolle, Stéphanie, Thomas‐Teinturier, Cécile, Zidane, Monia, Rubino, Carole, Veres, Cristina, Vu‐Bezin, Giao, Berchery, Delphine, Pluchart, Claire, Bondiau, Pierre‐Yves, Dumas, Agnès, Bougas, Nicolas, Grill, Jacques, and Dufour, Christelle

Subjects
CHILDHOOD cancer, ADULTS, CANCER survivors, FRENCH people, OBESITY, BRAIN tumors, RADIATION carcinogenesis
Abstract

Objective: The aim of this study was to identify risk factors for obesity in childhood cancer survivors (CCSs). Methods: The study included 3199 patients of the French Childhood Cancer Survivor Study cohort, with 303 patients with obesity who had returned the self‐questionnaire. Analyses were adjusted for social deprivation index and sex. Results: CCSs were less likely to have obesity (9.5%; 95% CI: 8.5%–10.5%) than expected from the general French population rates (12.5%; p = 0.0001). Nevertheless, brain tumor survivors were significantly more likely to develop obesity than the general French population (p = 0.0001). Compared with patients who did not receive radiotherapy to the pituitary gland, those who received a dose >5 Gy had an increased risk of obesity: relative risk 1.9 (95% CI: 1.2–3.1), 2.5 (95% CI: 1.7–3.7), and 2.6 (95% CI: 1.6–4.3), respectively, for participants with 6 to 20 Gy, 20 to 40 Gy, and ≥40 Gy of radiation. Etoposide administration significantly increased the risk of obesity (relative risk 1.7; 95% CI: 1.1–2.6). High social deprivation index was also a risk factor, just like BMI at diagnosis. Conclusions: Long‐term follow‐up of CCSs should include weight follow‐up during adulthood. [ABSTRACT FROM AUTHOR]

Published
2023
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31. The effect of thyroid dysfunction on breast cancer risk: an updated meta-analysis.

Author

Thi-Van-Trinh Tran, Kitahara, Cari Meinhold, Leenhardt, Laurence, de Vathaire, Florent, Boutron-Ruault, Marie-Christine, and Journy, Neige

Subjects
THYROID diseases, BREAST cancer, DISEASE risk factors, THYROID cancer, CANCER diagnosis, HYPERTHYROIDISM, POSTMENOPAUSE
Abstract

In a previous systematic review and meta-analysis of studies reporting associations between hyper-/hypothyroidism and breast cancer incidence published through 29 January 2019, we identified a higher risk with diagnosed hyperthyroidism compared to euthyroidism, but no association with diagnosed hypothyroidism. This 2-year updated meta-analysis aims to investigate the role of menopause in this association and the dose– response relationship with blood levels of thyroid-stimulating hormone (TSH) and thyroid hormones. After the exclusion of studies with only mortality follow-up, with thyroid dysfunction evaluated as a cancer biomarker or after prior breast cancer diagnosis, we reviewed 25 studies that were published up to 01 December 2021 and identified in MEDLINE, the COCHRANE library, Embase, or Web of Science; of these, 9 were included in the previous meta-analysis. Risk estimates from 22 of the 25 studies were included in the meta-analysis and pooled using random-effects models. Compared to euthyroidism, hyperthyroidism and hypothyroidism diagnoses were associated with higher (pooled risk ratio (RR): 1.12, 95% CI: 1.06–1.18, 3829 exposed cases) and lower risks (RR = 0.93, 95% CI: 0.86–1.00, 5632 exposed cases) of breast cancer, respectively. The increased risk after hyperthyroidism was greater among postmenopausal women (RR = 1.19, 95% CI 1.09–1.30) and the decreased risk after hypothyroidism was more pronounced among premenopausal women (RR = 0.69, 95% CI 0.53–0.89). Among women with no prior history of thyroid disease, every 1 mIU/L increase in TSH level was associated with a 0.8% (95% CI > 0–1.5%) lower risk of breast cancer. In conclusion, this meta-analysis supports an association between thyroid hormone levels and breast cancer risk, which could be modified by menopausal status. [ABSTRACT FROM AUTHOR]

Published
2023
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32. Smoking and Cannabis Use among Childhood Cancer Survivors: Results of the French Childhood Cancer Survivor Study

Author

Bougas, Nicolas, primary, Fresneau, Brice, additional, Pinto, Sandrine, additional, Mayet, Aurélie, additional, Marchi, Joffrey, additional, Pein, François, additional, Mansouri, Imene, additional, Journy, Neige M.Y., additional, Jackson, Angela, additional, Souchard, Vincent, additional, Demoor-Goldschmidt, Charlotte, additional, Vu-Bezin, Giao, additional, Rubino, Carole, additional, Oberlin, Odile, additional, Haddy, Nadia, additional, de Vathaire, Florent, additional, Allodji, Rodrigue S., additional, and Dumas, Agnès, additional

Published
2021
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33. Dose Estimation for the European Epidemiological Study on Pediatric Computed Tomography (EPI-CT)

Author

Thierry-Chef, Isabelle, primary, Ferro, Gilles, additional, Le Cornet, Lucian, additional, Dabin, Jérémie, additional, Istad, Tore S., additional, Jahnen, Andreas, additional, Lee, Choonsik, additional, Maccia, Carlo, additional, Malchair, Françoise, additional, Olerud, Hilde M., additional, Harbron, Richard W., additional, Figuerola, Jordi, additional, Hermen, Johannes, additional, Moissonnier, Monika, additional, Bernier, Marie-Odile, additional, de Basea, Magda Bosch, additional, Byrnes, Graham, additional, Cardis, Elisabeth, additional, Hauptmann, Michael, additional, Journy, Neige, additional, Kesminiene, Ausrele, additional, Meulepas, Johanna M., additional, Pokora, Roman, additional, and Simon, Steven L., additional

Published
2021
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35. Risk Factors of Subsequent Central Nervous System Tumors after Childhood and Adolescent Cancers: Findings from the French Childhood Cancer Survivor Study

Author

Journy, Neige Marie Yvanne, primary, Zrafi, Wael Salem, additional, Bolle, Stéphanie, additional, Fresneau, Brice, additional, Alapetite, Claire, additional, Allodji, Rodrigue Setcheou, additional, Berchery, Delphine, additional, Haddy, Nadia, additional, Kobayashi, Isao, additional, Labbé, Martine, additional, Pacquement, Hélène, additional, Pluchart, Claire, additional, Schwartz, Boris, additional, Souchard, Vincent, additional, Thomas-Teinturier, Cécile, additional, Veres, Cristina, additional, Vu-Bezin, Giao, additional, Diallo, Ibrahima, additional, and de Vathaire, Florent, additional

Published
2021
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36. A systematic review of occupational radiation individual dose monitoring among healthcare workers exposed in Africa

Author

Gbetchedji, Arnaud A, primary, Houndetoungan, Gilles D, additional, Hounsossou, Hubert C, additional, Journy, Neige, additional, Haddy, Nadia, additional, Rubino, Carole, additional, Biaou, Olivier, additional, Medenou, Daton, additional, Amoussou-Guenou, Kuassi M, additional, de Vathaire, Florent, additional, and Allodji, Rodrigue S, additional

Published
2020
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37. Dose-volume effects of breast cancer radiation therapy on the risk of second oesophageal cancer

Author

Journy, Neige, primary, Schonfeld, Sara J., additional, Hauptmann, Michael, additional, Roberti, Sander, additional, Howell, Rebecca M., additional, Smith, Susan A., additional, Vaalavirta, Leila, additional, Stovall, Marilyn, additional, van Leeuwen, Flora E., additional, Weathers, Rita E., additional, Hodgson, David, additional, Gilbert, Ethel S., additional, Berrington de Gonzalez, Amy, additional, and Morton, Lindsay M., additional

Published
2020
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38. Identifying clusters of health risk behaviors and their predictors in adult survivors of childhood cancer: A report from the French Childhood Cancer Survivor Study

Author

Pinto, Sandrine, primary, Fresneau, Brice, additional, Hounsossou, Hubert C., additional, Mayet, Aurélie, additional, Marchi, Joeffrey, additional, Pein, François, additional, Journy, Neige, additional, Mansouri, Imene, additional, Drubay, Damien, additional, Letort, Véronique, additional, Lemler, Sarah, additional, Demoor‐Goldschmidt, Charlotte, additional, Jackson, Angela, additional, Souchard, Vincent, additional, Vu‐Bezin, Giao, additional, Diallo, Ibrahima, additional, Rubino, Carole, additional, Oberlin, Odile, additional, Haddy, Nadia, additional, de Vathaire, Florent, additional, Dumas, Agnès, additional, and Allodji, Rodrigue S., additional

Published
2020
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39. Risk Factors for Small Adult Height in Childhood Cancer Survivors

Author

Demoor-Goldschmidt, Charlotte, primary, Allodji, Rodrigue S., additional, Journy, Neige, additional, Rubino, Carole, additional, Zrafi, Wael Salem, additional, Debiche, Ghazi, additional, Llanas, Damien, additional, Veres, Cristina, additional, Thomas-Teinturier, Cécile, additional, Pacquement, Hélène, additional, Vu-Bezin, Giao, additional, Fresneau, Brice, additional, Berchery, Delphine, additional, Bolle, Stephanie, additional, Diallo, Ibrahima, additional, Haddy, Nadia, additional, and de Vathaire, Florent, additional

Published
2020
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41. Cohort Profile:the EPI-CT study: a European pooled epidemiological study to quantify the risk of radiation-induced cancer from paediatric CT

Author

Bernier, Marie-Odile, Baysson, Hélène, Pearce, Mark S, Moissonnier, Monika, Cardis, Elisabeth, Hauptmann, Michael, Struelens, Lara, Dabin, Jeremie, Johansen, Christoffer, Journy, Neige, Laurier, Dominique, Blettner, Maria, Le Cornet, Lucian, Pokora, Roman, Gradowska, Patrycja, Meulepas, Johanna M, Kjaerheim, Kristina, Istad, Tore, Olerud, Hilde, Sovik, Aste, Bosch de Basea, Magda, Thierry-Chef, Isabelle, Kaijser, Magnus, Nordenskjöld, Arvid, Berrington de Gonzalez, Amy, Harbron, Richard W, Kesminiene, Ausrele, Bernier, Marie-Odile, Baysson, Hélène, Pearce, Mark S, Moissonnier, Monika, Cardis, Elisabeth, Hauptmann, Michael, Struelens, Lara, Dabin, Jeremie, Johansen, Christoffer, Journy, Neige, Laurier, Dominique, Blettner, Maria, Le Cornet, Lucian, Pokora, Roman, Gradowska, Patrycja, Meulepas, Johanna M, Kjaerheim, Kristina, Istad, Tore, Olerud, Hilde, Sovik, Aste, Bosch de Basea, Magda, Thierry-Chef, Isabelle, Kaijser, Magnus, Nordenskjöld, Arvid, Berrington de Gonzalez, Amy, Harbron, Richard W, and Kesminiene, Ausrele

Published
2019

42. Risk of subsequent primary leukaemias among 69,460 five-year survivors of childhood cancer diagnosed from 1940 to 2008 in Europe: A cohort study within PanCareSurFup

Author

Allodji, Rodrigue S., primary, Hawkins, Mike M., additional, Bright, Chloe J., additional, Fidler-Benaoudia, Miranda M., additional, Winter, David L., additional, Alessi, Daniela, additional, Fresneau, Brice, additional, Journy, Neige, additional, Morsellino, Vera, additional, Bárdi, Edit, additional, Bautz, Andrea, additional, Byrne, Julianne, additional, Feijen, Elizabeth (Lieke) AM., additional, Teepen, Jop C., additional, Vu-Bezin, Giao, additional, Rubino, Carole, additional, Garwicz, Stanislaw, additional, Grabow, Desiree, additional, Gudmundsdottir, Thorgerdur, additional, Guha, Joyeeta, additional, Hau, Eva-Maria, additional, Jankovic, Momcilo, additional, Kaatsch, Peter, additional, Kaiser, Melanie, additional, Linge, Helena, additional, Muraca, Monica, additional, Llanas, Damien, additional, Veres, Cristina, additional, Øfstaas, Hilde, additional, Diallo, Ibrahima, additional, Mansouri, Imene, additional, Ronckers, Cecile M., additional, Skinner, Roderick, additional, Terenziani, Monica, additional, Wesenberg, Finn, additional, Wiebe, Thomas, additional, Sacerdote, Carlotta, additional, Jakab, Zsuzsanna, additional, Haupt, Riccardo, additional, Lähteenmäki, Päivi, additional, Zaletel, Lorna Zadravec, additional, Kuehni, Claudia E., additional, Winther, Jeanette F., additional, Michel, Gisela, additional, Kremer, Leontien C.M., additional, Hjorth, Lars, additional, Haddy, Nadia, additional, de Vathaire, Florent, additional, and Reulen, Raoul C., additional

Published
2019
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43. Recommendations for the organisation of care in paediatric radiation oncology across Europe: a SIOPE–ESTRO–PROS–CCI-Europe collaborative project in the framework of the JARC

Author

Janssens, Geert O., primary, Timmermann, Beate, additional, Laprie, Anne, additional, Mandeville, Henry, additional, Padovani, Laetitia, additional, Chargari, Cyrus, additional, Journy, Neige, additional, Kameric, Lejla, additional, Kienesberger, Anita, additional, Brunhofer, Melanie, additional, Kozhaeva, Olga, additional, Gasparotto, Chiara, additional, Kearns, Pamela, additional, Boterberg, Tom, additional, Lievens, Yolande, additional, and Vassal, Gilles, additional

Published
2019
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44. Long-term health status of high-risk neuroblastoma survivors treated with high-dose chemotherapy and hematopoietic stem cell transplantation.

Author

Haghiri, Sandrine, primary, Fayech, Chiraz, additional, Dufour, Christelle, additional, Pasqualini, Claudia, additional, Bolle, Stephanie, additional, Boumaraf, Amel, additional, Belhout, Amel, additional, Journy, Neige, additional, Souchard, Vincent, additional, Vu-Bezin, Giao, additional, Veres, Cristina, additional, Haddy, Nadia, additional, De Vathaire, Florent, additional, Valteau-Couanet, Dominique, additional, and Fresneau, Brice, additional

Published
2019
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45. New insights in cisplatin and radiation-induced ototoxicity: A French Childhood Cancer Survivors Study (FCCSS).

Author

Fresneau, Brice, primary, Santos, Felicia, additional, Allodji, Rodrigue, additional, Fayech, Chiraz, additional, Bolle, Stephanie, additional, Vu-Bezin, Giao, additional, Souchard, Vincent, additional, Haddy, Nadia, additional, Doz, Francois P., additional, Berchery, Delphine, additional, Lemire, Pierre, additional, Journy, Neige, additional, Veres, Cristina, additional, Brugieres, Laurence, additional, Valteau-Couanet, Dominique, additional, Diallo, Ibrahima, additional, Dufour, Christelle, additional, and De Vathaire, Florent, additional

Published
2019
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46. Risk Factors for Small Adult Height in Childhood Cancer Survivors

Author

Demoor-Goldschmidt, Charlotte, primary, Allodji, Rodrigue S., additional, Journy, Neige, additional, Rubino, Carole, additional, Zrafi, Wael Salem, additional, Bediche, Ghazi, additional, Llanas, Damien, additional, Veres, Cristina, additional, Thomas-Teinturier, Cécile, additional, Pacquement, Hélène, additional, Vu-Bezin, Giao, additional, Fresneau, Brice, additional, Bergery, Delphine, additional, Bolle, Stephanie, additional, Diallo, Ibrahima, additional, Haddy, Nadia, additional, and de Vathaire, Florent, additional

Published
2019
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47. Cumulative Radiation Exposures from CT Screening and Surveillance Strategies for von Hippel-Lindau–associated Solid Pancreatic Tumors

Author

Tirosh, Amit, primary, Journy, Neige, additional, Folio, Les R., additional, Lee, Choonsik, additional, Leite, Christiane, additional, Yao, Jianhua, additional, Kovacs, William, additional, Linehan, W. Marston, additional, Malayeri, Ashkan, additional, Kebebew, Electron, additional, and Berrington de González, Amy, additional

Published
2019
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48. Thyroid dysfunction and cancer incidence: a systematic review and meta-analysis.

Author

Thi-Van-Trinh Tran, Kitahara, Cari M., de Vathaire, Florent, Boutron-Ruault, Marie-Christine, and Journy, Neige

Subjects
META-analysis, PROSTATE cancer, HYPERTHYROIDISM, CANCER diagnosis, THYROID cancer
Abstract

In this study, we aimed to evaluate site-specific cancer risks a ssociated with hyperthyroidism or hypothyroidism. We performed a systematic review of observational studies reporting associations between hyperthyroidism or hypothyroidism and subsequent site-specific cancer incidence, in MEDLINE and the COCHRANE library (inception-28/01/2019) (PROSPERO: CRD42019125094). We excluded studies with thyroid dysfunction evaluated as a cancer biomarker or after prior cancer diagnosis and those considering transient thyroid dysfunction during pregnancy or severe illnesses. Risk of bias was assessed using a modified Newcastle-Ottawa scale. Risk estimates were pooled using random-effects models when =5 studies reported data for a specific cancer site. Twenty studies were included, of which 15 contributed to the me ta-analysis. Compared to euthyroidism, hyperthyroidism was associated with higher risks of thyroid (pooled risk ratio: 4.49, 95%CI: 2.84-7.12), breast (pooled risk ratio: 1.20, 95%CI: 1.04-1.38), and prostate (pooled risk ratio: 1.35, 95%CI: 1.05-1.74), but not respiratory tract (pooled risk ratio: 1.06, 95%CI: 0.80-1.42) cancers. Hypothyroidism was associated with a higher risk of thyroid cancer within the first 10 years of follow-up on ly (pooled risk ratio: 3.31, 95%CI: 1.20-9.13). There was no or limited evidence of thyroid dysfunction-related risks of other cancer sites. In conclusion, thyroid dysfunction was associated with increased risks of thyroid, breast, and prostate cancers. However, it remains unclear whether these findings represent causal relationships because information on treatments and potential confounders was frequently lacking. [ABSTRACT FROM AUTHOR]

Published
2020
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49. Cohort Profile: the EPI-CT study: a European pooled epidemiological study to quantify the risk of radiation-induced cancer from paediatric CT

Author

Bernier, Marie-Odile, primary, Baysson, Hélène, additional, Pearce, Mark S, additional, Moissonnier, Monika, additional, Cardis, Elisabeth, additional, Hauptmann, Michael, additional, Struelens, Lara, additional, Dabin, Jeremie, additional, Johansen, Christoffer, additional, Journy, Neige, additional, Laurier, Dominique, additional, Blettner, Maria, additional, Le Cornet, Lucian, additional, Pokora, Roman, additional, Gradowska, Patrycja, additional, Meulepas, Johanna M, additional, Kjaerheim, Kristina, additional, Istad, Tore, additional, Olerud, Hilde, additional, Sovik, Aste, additional, Bosch de Basea, Magda, additional, Thierry-Chef, Isabelle, additional, Kaijser, Magnus, additional, Nordenskjöld, Arvid, additional, Berrington de Gonzalez, Amy, additional, Harbron, Richard W, additional, and Kesminiene, Ausrele, additional

Published
2018
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