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1. P2Y12 Inhibitor Loading Time Before Elective PCI and the Prevention of Myocardial Necrosis

Author

Roule, Vincent, Beygui, Farzin, Cayla, Guillaume, Rangé, Grégoire, Motovska, Zuzana, Delarche, Nicolas, Jourda, François, Goube, Pascal, Guedeney, Paul, Zeitouni, Michel, El Kasty, Mohamad, Laredo, Mikael, Dumaine, Raphaëlle, Ducrocq, Gregory, Derimay, François, Van Belle, Eric, Manigold, Thibaut, Cador, Romain, Combaret, Nicolas, Vicaut, Eric, Montalescot, Gilles, and Silvain, Johanne

Published
2024
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2. Rapid ventricular tachycardia in patients with tetralogy of Fallot and implantable cardioverter-defibrillator: Insights from the DAI-T4F nationwide registry

Author

Laredo, Mikael, Duthoit, Guillaume, Sacher, Frédéric, Anselme, Frédéric, Audinet, Caroline, Bessière, Francis, Bordachar, Pierre, Bouzeman, Abdeslam, Boveda, Serge, Bun, Sok Sithikun, Chassignolle, Morgane, Clerici, Gaël, Da Costa, Antoine, de Guillebon, Maxime, Defaye, Pascal, Elbaz, Nathalie, Eschalier, Romain, Extramiana, Fabrice, Fauchier, Laurent, Hermida, Alexis, Gandjbakhch, Estelle, Garcia, Rodrigue, Gourraud, Jean-Baptiste, Guenancia, Charles, Guy-Moyat, Benoit, Irles, Didier, Iserin, Laurence, Jourda, François, Koutbi, Linda, Labombarda, Fabien, Ladouceur, Magalie, Lagrange, Philippe, Lellouche, Nicolas, Mansourati, Jacques, Marquié, Christelle, Martins, Raphael, Massoulié, Grégoire, Mathiron, Amel, Maury, Philippe, Messali, Anne, Milhem, Antoine, Mondoly, Pierre, Nguyen, Cédric, Ninni, Sandro, Pasquié, Jean Luc, Pierre, Bertrand, Pujadas, Penelope, Sellal, Jean-Marc, Thambo, Jean-Benoit, Walton, Camille, Winum, Pierre, Zakine, Cyril, Zhao, Alexandre, Jouven, Xavier, Combes, Nicolas, Marijon, Eloi, and Waldmann, Victor

Published
2023
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3. Sex Differences in Outcomes of Tetralogy of Fallot Patients With Implantable Cardioverter-Defibrillators

Author

Akret, Chrystelle, Albenque, Jean-Paul, Algalarrondo, Vincent, Alonso, Christine, Amet, Denis, Ansselme, Frédéric, Asselin, Anouk, Audinet, Caroline, Badenco, Nicolas, Bader, Hugues, Badoz, Marc, Baudinaud, Pierre, Behar, Nathalie, Ben Kilani, Mouna, Bernard, Yvette, Bertaux, Géraldine, Bertrand, Cathy, Bessiere, Francis, Blangy, Hughes, Bonnet, Damien, Bordchar, Pierre, Bouzeman, Abdeslam, Boveda, Serge, Bru, Paul, Bun, Sok Sithikun, Carabelli, Adrien, Cardin, Christèle, Cauchemez, Bruno, Chalbia, Tej, Champ-Rigot, Laure, Chastre, Thomas, Chevallier, Philippe, Clementy, Nicolas, Clerici, Gaël, Combes, Nicolas, Combes, Stéphane, Da Costa, Antoine, De Chillou, Christian, De Guillebon, Maxime, Defaye, Pascal, Degand, Bruno, Deharo, Jean-Claude, Derval, Nicolas, Di Filippo, Sylvie, Domain, Guillaume, Dompnier, Antoine, Dulac, Arnaud, Duparc, Alexandre, Duplantier, D Cécile, Duthoit, Guillaume, El Bouazzaoui, Rim, Elbaz, Nathalie, Enache, Bogdan, Eschalier, Romain, Extramiana, Fabrice, Fauchier, Laurent, Fiorello, Pierre, Frey, Pierre, Freysz, Luc, Galand, Vincent, Gandjbakhch, Estelle, Garcia, Rodrigue, Gardey, Kevin, Geoffroy, Olivier, Godin, Bénédicte, Gourraud, Jean-Baptiste, Goussot, Samuel, Grimard, Caroline, Guenancia, Charles, Guichard, Jean-Baptiste, Guy-Moyat, Benoit, Haissaguerre, Michel, Halimi, Franck, Hamon, David, Hascoet, Sébastien, Hasni, Karim, Hermida, Alexis, Hermida, Jean-Sylvain, Hidden-Lucet, Françoise, Hocini, Mélèze, Hourdain, Jérome, Irles, Didier, Iserin, Laurence, Jacon, Peggy, Jauvert, Gaël, Jean, Frédéric, Johnson, Nicolas, Jourda, François, Khattar, Pierre, Khoueiry, Ziad, Koutbi, Rita, Labombarda, Fabien, Laborie, Guillaume, Lactu, Gabriel, Ladouceur, Magalie, Lagrange, Philippe, Lallemand, Pierre-Marc, Laredo, Mikael, Laurent, Gabriel, Lavergne, Thomas, Lazarus, Arnaud, Le Gloan, Laurianne, Leclercq, Christophe, Leenhardt, Antoine, Lellouche, Nicolas, Loose, Christophe, Mabo, Philippe, Maltret, Alice, Mandel, Franck, Mansourati, Jacques, Marijon, Eloi, Marquie, Christelle, Martins, Raphaël, Mathiron, Amel, Maupain, Carole, Maury, Philippe, Messali, Anne, Milhelm, Antoine, Milliez, Paul, Mirolo, Adrian, Mondoly, Pierre, Moubarak, Ghassan, Mourot, Stéphane, Nguyen, Cédric, Ollitrault, Jacky, Ollitrault, Pierre, Otmani, Akli, Pasquie, Jean-Luc, Pavin, Dominique, Perier, Marie-Cécile, Philibert, Séverinne, Poindron, Damien, Potelle, Charlotte, Probst, Vincent, Puie, Paul, Pujadas, Penelope, Rollin, Anne, Romeyer-Bouchard, Cécile, Sacher, Frédéric, Sadoul, Nicolas, Sagnard, Audrey, Sagnol, Pascal, Savoure, Arnaud, Scarlatti, Didier, Sellal, Jean Marc, Sharifzadehgan, Ardalan, Squara, Fabien, Tanese, Nikita, Thambo, Jean Benoit, Thomas, Olivier, Varlet, Emie, Venier, Sandrine, Stephanopoli, Quentin Voglimacci, Waintraub, Xavier, Waldmann, Victor, Walton, Camille, Wiart, Françoise, Winum, Pierre, Zakine, Cyril, Zhao, Alexandre, Zouaghi, Amir, Koutbi, Linda, Bessière, Francis, Marquié, Christelle, Bordachar, Pierre, Al Arnaout, Alain, Anselme, Frédéric, Chassignolle, Morgane, de Guillebon, Maxime, Massoulié, Grégoire, Narayanan, Kumar, Ninni, Sandro, Pierre, Bertrand, Pasquié, Jean-Luc, Thambo, Jean-Benoit, and Jouven, Xavier

Published
2022
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4. Impact of Pulmonary Valve Replacement on Ventricular Arrhythmias in Patients With Tetralogy of Fallot and Implantable Cardioverter-Defibrillator

Author

Bessière, Francis, Gardey, Kévin, Bouzeman, Abdeslam, Duthoit, Guillaume, Koutbi, Linda, Labombarda, Fabien, Marquié, Christelle, Gourraud, Jean Baptiste, Mondoly, Pierre, Sellal, Jean Marc, Bordachar, Pierre, Hermida, Alexis, Anselme, Frédéric, Asselin, Anouk, Audinet, Caroline, Bernard, Yvette, Boveda, Serge, Chevalier, Philippe, Clerici, Gael, da Costa, Antoine, de Guillebon, Maxime, Defaye, Pascal, Eschalier, Romain, Garcia, Rodrigue, Guenancia, Charles, Guy-Moyat, Benoit, Henaine, Roland, Irles, Didier, Iserin, Laurence, Jourda, François, Ladouceur, Magalie, Lagrange, Philippe, Laredo, Mikael, Mansourati, Jacques, Massoulié, Grégoire, Mathiron, Amel, Maury, Philippe, Nguyen, Cédric, Ninni, Sandro, Perier, Marie-Cécile, Pierre, Bertrand, Sacher, Frédéric, Walton, Camille, Winum, Pierre, Martins, Raphaël, Pasquié, Jean Luc, Thambo, Jean Benoit, Jouven, Xavier, Combes, Nicolas, Di Filippo, Sylvie, Marijon, Eloi, and Waldmann, Victor

Published
2021
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5. Hydroxychloroquine in mild-to-moderate coronavirus disease 2019: a placebo-controlled double blind trial

Author

Brangier, Antoine, Codron, Philippe, Lemée, Jean Michel, Pichon, Virginie, Dhersin, Robin, Urbanski, Geoffrey, Lavigne, Christian, Courtois, Roxane, Danielou, Hélène, Lebreton, Jonathan, Vatan, Rémi, Crochette, Nicolas, Lainé, Jean-Baptiste, Perez, Lucia, Blanchi, Sophie, Hitoto, Hikombo, Bernard, Louis, Maillot, François, Marchand Adam, Sylvain, Talarmin, Jean-Philippe, Gaigneux, Emeline, Motte-Vincent, Pauline, Morrier, Marine, Merrien, Dominique, Bleher, Yves, Flori, Maxime, Ducet-Boiffard, Amélie, Colin, Orane, Février, Ronan, Thill, Pauline, Tetart, Macha, Demaeght, François, Lafond-Desmurs, Barthelemy, Pradier, Maxime, Meybeck, Agnes, Picaud, Marjorie, Prazuck, Thierry, Chapelet, Guillaume, Rouaud, Agnès, Le Turnier, Paul, Sunder, Simon, Lorleac'h, Aurélien, Dollon, Christophe, Jacquet, Antoine, Le Vely, Francois, Gazeau, Pierre, Ansart, Séverine, Roger, Hélène, Laterza, François, Buzelé, Rodolphe, Tahmi, Fella, Lepeule, Raphael, Lacombe, Karine, Lefebvre, Bénédicte, Célarier, Thomas, Gagneux-Brunon, Amandine, Botelho-Nevers, Elisabeth, Bernard, Marc, Garnier, Camille, Mourguet, Morgane, Pugnet, Gregory, Vienne-Noyes, Sara, Martin-Blondel, Guillaume, Delobel, Pierre, Grouteau, Gaspard, Debard, Alexa, Guilleminault, Laurent, Arias, Pauline, Chakvetadze, Catherine, Flateau, Clara, Kopp, Aude, Putot, Alain, Barben, Jeremy, Mouries Martin, Suzanne, Nuss, Valentine, Piroth, Lionel, Claessens, Yann-Erick, Hentgen, Veronique, Martinot, Martin, Bach-Bunner, Maxime, Bonijoly, Thomas, Gravier, Simon, Michel, Jean-Marc, Andreu, Mathilde, Roriz, Mélanie, Baldolli, Aurélie, Brochard, Julia, Grossi, Olivier, Pineau, Samuel, Brisset, Josselin, Desvaux, Edouard, Gondran, Guillaume, Faucher, Jean-François, Quesnel, Paul-Antoine, Bezanahary, Holy, Danthu, Clément, Gutierrez, Blandine, Ly, Kim, Simonneau, Yannick, Cypierre, Anne, Pinet, Pauline, Durox, Hélène, Ducroix-Roubertou, Sophie, Genet, Claire, Beraud, Guillaume, Le Moal, Gwenael, Rammaert, Blandine, Lanoix, Jean-Philippe, Andrejak, Claire, Joseph, Cédric, Soriot-Thomas, Sandrine, Dhote, Robin, Abad, Sébastien, Benainous, Ruben, Boitiaux, Jean-François, Briend, Guillaume, Gonfroy, Celine, Harent, Stanislas, Lagrange, Aurore, Tone, Alina, Wayenberg, Laura, Desoutter, Sophie, Ettahar, Nicolas, Gey, Thomas, Leroy, Vincent, Gaillard, Sacha, Toma, Andrea, Broussier, Amaury, Etienne, Sandrine, Spivac, Yann, Martha, Benoit, Roch, Nathalie, Diaz, Pierre, N’guyen Baranoff, Danièle, Rebaudet, Stanislas, Jourda, François, Zeller, Valérie, Bienvenu, Boris, Boyer, Arnaud, Pellier, Isabelle, Mercat, Alain, Darsonval, Astrid, Blanchet, Odile, Custaud, Marc-Antoine, Lefeuvre, Caroline, Parot-Schinkel, Elsa, Vielle, Bruno, Briet, Marie, Roy, Pierre-Marie, Dubée, Vincent, Guidet, Bertrand, Mismetti, Patrick, Vicaut, Eric, Sanchez, Olivier, Girard, Philippe, Elias, Antoine, Couturaud, Francis, Gable, Béatrice, Lazareff, Sybille, Carballido, Loïc, Hue, Catherine, Chrétien, Jean-Marie, Goraguer, Adrien, Eeckhoutte, Lucie van, Abbara, Chadi, Boucher, Sophie, Devaud, Edouard, Robineau, Olivier, Rispal, Patrick, Guimard, Thomas, d’Anglejean, Emma, and Diamantis, Sylvain

Published
2021
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6. Ticagrelor versus clopidogrel in elective percutaneous coronary intervention (ALPHEUS): a randomised, open-label, phase 3b trial

Author

SILVAIN, Johanne, COLLET, Jean-Philippe, MONTALESCOT, Gilles, KERNEIS, Mathieu, BRAIK, Nassim, BARTHELEMY, Olivier, HELFT, Gérard, LEFEUVRE, Claude, CHOUSSAT, Rémi, HAUGUEL, Marie, ZEITOUNI, Michel, CUISSET, Thomas, BONNET, Jean-Louis, DEHARO, Pierre, LATTUCA, Benoit, CAYLA, Guillaume, CORNILLET, Luc, LEDERMANN, Bertrand, LONJON, Clément, SCHMUTZ, Laurent, RANGE, Grégoire, ALBERT, Franck, DEMICHELI, Thibault, ROUSSEL, Laurent, BENSAID, Reda, THUAIRE, Christophe, DILLINGER, Jean-Guillaume, HENRY, Patrick, MANZO-SILBERMAN, Stéphane, SIDERIS, Georgios, LOGEART, Damien, SPAGNOLI, Vincent, CACOUB, Léa, POUILLOT, Christophe, VI-FANE, Jean Richard, GLASENAPP, Jens, BOUGRINI, Karim, COMBARET, Nicolas, MOTREFF, Pascal, SOUTEYRAND, Géraud, AMONCHOT, Aimé, MOUYEN, Thomas, LHERMUSIER, Thibault, CARRIE, Didier, BOUISSET, Frédéric, CHOLLET, Thomas, CAMPELO-PARADA, Francisco, DELARCHE, Nicolas, SCHIELE, François, BESUTTI, Mathieu, HAUGUEL-MOREAU, Marie, EL MAHMOUD, Rami, CAUSSIN, Christophe, ZOHEIR, Mami, VEUGEOIS, Aurelie, DIBIE, Alain, VARENNE, Olivier, PICARD, Fabien, LAFONT, Alexandre, ADJEDJ, Julien, DEGRELL, Philippe, BEYGUI, Farzin, SABATIER, Rémi, ROULE, Vincent, BIGNON, Mathieux, BLANCHART, Katrien, ARDOUIN, Pierre, LEMAITRE, Adrien, BRIET, Clément, BOUERI, Ziad, GOUBE, Pascal, COSTE, Pierre, CETRAN, Laura, CLERC, Jérôme, LE BRETON, Hervé, BOULMIER, Dominique, AUFFRET, Vincent, LABEQUE, Jean-Noël, BONAS, Jean-Luc, GEORGES, Jean-Louis, LIVAREK, Bernard, BLICQ, Elodie, BARON, Nicolas, GIBAULT-GENTY, Géraldine, COTTIN, Yves, LHUILLIER, Isabelle, RICHARD, Carole, LORGIS, Luc, BUFFET, Philippe, SPAULDING, Christian, KARAM, Nicole, PUYMIRAT, Etienne, MENNUNI, Marco, POULIDAKIS, Emmanuel, BONNEVIE, Lionel, BOCCARA, Franck, CHAUVET, Marion, DUFOUR, Laurie, ANCEDY, Yann, EDERHY, Stéphane, ETIENNEY, Arnaud, BELLEMAIN-APPAIX, Anne, BITTON, Nathaniel, JACQ, Laurent, SAINT-ETIENNE, Christophe, LECLERCQ, Florence, ROUBILLE, François, RIOUFOL, Gilles, DERIMAY, François, GORALSKI, Marc, YAFI, Wael, FILIPPI, Emmanuelle, KERMARREC, Alain, LE RAY, Christophe, MERLET, Antoine, LOIRAT, Aurelie, BRUNEL, Philippe, BRUNET, Damien, RAVISY, Jack, MOCK, Laurent, MOLINS, Guillaume, CARRE, Max, BRESSOLLETTE, Erwan, CHRISTIAENS, Luc, LARRIEU-ARDILOUZE, Elisa, CADOR, Romain CADOR, VAN BELLE, Eric, LEMESLE, Gilles, DELHAYE, Cédric, VINCENT, Flavien, POROUCHANI, Sina, SPILLEMAEKER, Hugues, PETIT, Katy, RESSENCOURT, Olivier, HUMEAU, Vincent, JOURDA, François, ARNOULD, Marc-Antoine, CHASSAING, Stephen, ISAAZ, Karl, PAYOT, Laurent, MONTSEGU, Jacques, FAURIE, Benjamin, PANSIERI, Michel, METGE, Marc, MOUSSA, Karim, PANKERT, Mathieu, MOREL, Olivier, HESS, Sébastien, MAILLARD, Luc, MANIGOLD, Thibault, LETOCART, Vincent, PLESSIS, Julien, BERTHOME, Pauline, BONIN, Mickael, HUCHET, François, TEIGER, Emmanuel, GALLET, Romain, MOUILLET, Gauthier, BOUKANTAR, Madjid, NEJJARI, Mohammed, ATTIAS, David, STEINECKER, Mathieu, MOTOVSKA, Zuzana, KOZEL, Martin, STELMACH, Zdenko, HLINOMAZ, Ota, REZEK, Michal, NOVAK, Martin, SITAR, Jan, SEMENKA, Jiri, KALA, Petr, BOCEK, Otakar, ŠTIPAL, Roman, POLOCZEK, Martin, KANOVSKÝ, Jan, JERABEK, Petr, KARASEK, Jiří, HRUSKOVA, Sylvie, BRANNY, Marian, MROZEK, Jan, GREZL, Tomas, PLEVA, Leos, KUKLA, Pavel, PORZER, Martin, Silvain, Johanne, Lattuca, Benoit, Beygui, Farzin, Rangé, Grégoire, Motovska, Zuzana, Dillinger, Jean-Guillaume, Boueri, Ziad, Brunel, Philippe, Lhermusier, Thibault, Pouillot, Christophe, Larrieu-Ardilouze, Elisa, Boccara, Franck, Labeque, Jean-Noël, Guedeney, Paul, El Kasty, Mohamad, Laredo, Mikael, Dumaine, Raphaëlle, Ducrocq, Grégory, Collet, Jean-Philippe, Cayla, Guillaume, Blanchart, Katrien, Kala, Petr, Vicaut, Eric, and Montalescot, Gilles

Published
2020
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7. Blunting periprocedural myocardial necrosis: Rationale and design of the randomized ALPHEUS study

Author

Silvain, Johanne, Cayla, Guillaume, Beygui, Farzin, Range, Grégoire, Lattuca, Benoit, Collet, Jean-Philippe, Dillinger, Jean-Guillaume, Boueri, Ziad, Brunel, Philippe, Pouillot, Christophe, Boccara, Franck, Christiaens, Luc, Labeque, Jean-Noël, Lhermusier, Thibault, Georges, Jean-Louis, Bellemain-Appaix, Anne, Le Breton, Hervé, Hauguel-Moreau, Marie, Saint-Etienne, Christophe, Caussin, Christophe, Jourda, François, Motovska, Zuzana, Guedeney, Paul, El Kasty, Mohamad, Laredo, Mikael, Dumaine, Raphaëlle, Ducrocq, Grégory, Vicaut, Eric, and Montalescot, Gilles

Published
2020
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8. Exclusion of Intra-Atrial Thrombus Diagnosis Using D-Dimer Assay Before Catheter Ablation of Atrial Fibrillation

Author

Al Arnaout, Alain, Amara, Walid, Amelot, Mathieu, Bars, Clément, Becoulet, Lucile, Bru, Paul, Chevalier, Philippe, Darmon, Jean-Philippe, Deharo, Jean-Claude, Dompnier, Antoine, Duplantier-Duchene, Cécile, Extramiana, Fabrice, Faugier, Jean-Paul, Guenancia, Charles, Horvilleur, Jérôme, Jourda, François, Laurent, Gabriel, Lellouche, Nicolas, Magnin Poull, Isabelle, Piot, Olivier, Roux, Antoine, Saludas, Yannick, Seitz, Julien, Taieb, Jérôme, Milhem, Antoine, Ingrand, Pierre, Tréguer, Frédéric, Cesari, Olivier, Da Costa, Antoine, Pavin, Dominique, Rivat, Philippe, Badenco, Nicolas, Abbey, Sélim, Zannad, Noura, Winum, Pierre François, Mansourati, Jacques, Maury, Philippe, Bader, Hugues, Savouré, Arnaud, Sacher, Frédéric, Andronache, Marius, Allix-Béguec, Caroline, De Chillou, Christian, and Anselme, Frédéric

Published
2019
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9. P2Y12 inhibitor loading time before elective PCI and the prevention of myocardial necrosis

Author

Roule, Vincent, primary, Beygui, Farzin, additional, Cayla, Guillaume, additional, Range, Grégoire, additional, Motovska, Zuzana, additional, Delarche, Nicolas, additional, Jourda, François, additional, Goube, Pascal, additional, Guedeney, Paul, additional, Zeitouni, Michel, additional, El Kasty, Mohamad, additional, Laredo, Mikael, additional, Dumaine, Raphaëlle, additional, Ducrocq, Gregory, additional, Derimay, François, additional, Van Belle, Eric, additional, Manigold, Thibaut, additional, Cador, Romain, additional, Combaret, Nicolas, additional, Vicaut, Eric, additional, Montalescot, Gilles, additional, and Silvain, Johanne, additional

Published
2023
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10. Long-Term Follow-Up of Patients With Tetralogy of Fallot and Implantable Cardioverter Defibrillator: The DAI-T4F Nationwide Registry

Author

Waldmann, Victor, Bouzeman, Abdeslam, Duthoit, Guillaume, Koutbi, Linda, Bessiere, Francis, Labombarda, Fabien, Marquié, Christelle, Gourraud, Jean Baptiste, Mondoly, Pierre, Sellal, Jean Marc, Bordachar, Pierre, Hermida, Alexis, Anselme, Frédéric, Asselin, Anouk, Audinet, Caroline, Bernard, Yvette, Boveda, Serge, Bru, Paul, Bun, Sok Sithikun, Clerici, Gael, Da Costa, Antoine, de Guillebon, Maxime, Defaye, Pascal, Elbaz, Nathalie, Eschalier, Romain, Garcia, Rodrigue, Guenancia, Charles, Guy-Moyat, Benoit, Halimi, Franck, Irles, Didier, Iserin, Laurence, Jourda, François, Ladouceur, Magalie, Lagrange, Philippe, Laredo, Mikael, Mansourati, Jacques, Massoulié, Grégoire, Mathiron, Amel, Maury, Philippe, Messali, Anne, Narayanan, Kumar, Nguyen, Cédric, Ninni, Sandro, Perier, Marie-Cécile, Pierre, Bertrand, Pujadas, Penelope, Sacher, Frédéric, Sagnol, Pascal, Sharifzadehgan, Ardalan, Walton, Camille, Winum, Pierre, Zakine, Cyril, Fauchier, Laurent, Martins, Raphael, Pasquié, Jean Luc, Thambo, Jean Benoit, Jouven, Xavier, Combes, Nicolas, and Marijon, Eloi

Published
2020
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11. P2Y12Inhibitor Loading Time Before Elective PCI and the Prevention of Myocardial Necrosis

Author

Roule, Vincent, Beygui, Farzin, Cayla, Guillaume, Rangé, Grégoire, Motovska, Zuzana, Delarche, Nicolas, Jourda, François, Goube, Pascal, Guedeney, Paul, Zeitouni, Michel, El Kasty, Mohamad, Laredo, Mikael, Dumaine, Raphaëlle, Ducrocq, Gregory, Derimay, François, Van Belle, Eric, Manigold, Thibaut, Cador, Romain, Combaret, Nicolas, Vicaut, Eric, Montalescot, Gilles, and Silvain, Johanne

Abstract

There are dated and conflicting data about the optimal timing of initiation of P2Y12inhibitors in elective percutaneous coronary intervention (PCI). Peri-PCI myocardial necrosis is associated with poor outcomes. We aimed to assess the impact of the P2Y12inhibitor loading time on periprocedural myocardial necrosis in the population of the randomized Assessment of Loading With the P2Y12Inhibitor Ticagrelor or Clopidogrel to Halt Ischemic Events in Patients Undergoing Elective Coronary Stenting (ALPHEUS) trial, which compared ticagrelor with clopidogrel in high-risk patients who received elective PCI.

Published
2024
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12. Sex Differences in Outcomes of Tetralogy of Fallot Patients With Implantable Cardioverter-Defibrillators

Author

Waldmann, Victor, primary, Bouzeman, Abdeslam, additional, Duthoit, Guillaume, additional, Koutbi, Linda, additional, Bessière, Francis, additional, Labombarda, Fabien, additional, Marquié, Christelle, additional, Gourraud, Jean-Baptiste, additional, Mondoly, Pierre, additional, Sellal, Jean Marc, additional, Bordachar, Pierre, additional, Hermida, Alexis, additional, Al Arnaout, Alain, additional, Anselme, Frédéric, additional, Audinet, Caroline, additional, Bernard, Yvette, additional, Boveda, Serge, additional, Bun, Sok Sithikun, additional, Chassignolle, Morgane, additional, Clerici, Gaël, additional, Da Costa, Antoine, additional, de Guillebon, Maxime, additional, Defaye, Pascal, additional, Elbaz, Nathalie, additional, Eschalier, Romain, additional, Garcia, Rodrigue, additional, Guenancia, Charles, additional, Guy-Moyat, Benoit, additional, Halimi, Franck, additional, Irles, Didier, additional, Iserin, Laurence, additional, Jourda, François, additional, Ladouceur, Magalie, additional, Lagrange, Philippe, additional, Laredo, Mikael, additional, Mansourati, Jacques, additional, Massoulié, Grégoire, additional, Mathiron, Amel, additional, Maury, Philippe, additional, Messali, Anne, additional, Narayanan, Kumar, additional, Nguyen, Cédric, additional, Ninni, Sandro, additional, Perier, Marie-Cécile, additional, Pierre, Bertrand, additional, Pujadas, Penelope, additional, Sacher, Frédéric, additional, Sagnol, Pascal, additional, Sharifzadehgan, Ardalan, additional, Walton, Camille, additional, Winum, Pierre, additional, Zakine, Cyril, additional, Fauchier, Laurent, additional, Martins, Raphaël, additional, Pasquié, Jean-Luc, additional, Thambo, Jean-Benoit, additional, Jouven, Xavier, additional, Combes, Nicolas, additional, Marijon, Eloi, additional, Akret, Chrystelle, additional, Albenque, Jean-Paul, additional, Algalarrondo, Vincent, additional, Alonso, Christine, additional, Amet, Denis, additional, Ansselme, Frédéric, additional, Asselin, Anouk, additional, Badenco, Nicolas, additional, Bader, Hugues, additional, Badoz, Marc, additional, Baudinaud, Pierre, additional, Behar, Nathalie, additional, Ben Kilani, Mouna, additional, Bertaux, Géraldine, additional, Bertrand, Cathy, additional, Bessiere, Francis, additional, Blangy, Hughes, additional, Bonnet, Damien, additional, Bordchar, Pierre, additional, Bru, Paul, additional, Carabelli, Adrien, additional, Cardin, Christèle, additional, Cauchemez, Bruno, additional, Chalbia, Tej, additional, Champ-Rigot, Laure, additional, Chastre, Thomas, additional, Chevallier, Philippe, additional, Clementy, Nicolas, additional, Combes, Stéphane, additional, De Chillou, Christian, additional, De Guillebon, Maxime, additional, Degand, Bruno, additional, Deharo, Jean-Claude, additional, Derval, Nicolas, additional, Di Filippo, Sylvie, additional, Domain, Guillaume, additional, Dompnier, Antoine, additional, Dulac, Arnaud, additional, Duparc, Alexandre, additional, Duplantier, D Cécile, additional, El Bouazzaoui, Rim, additional, Enache, Bogdan, additional, Extramiana, Fabrice, additional, Fiorello, Pierre, additional, Frey, Pierre, additional, Freysz, Luc, additional, Galand, Vincent, additional, Gandjbakhch, Estelle, additional, Gardey, Kevin, additional, Geoffroy, Olivier, additional, Godin, Bénédicte, additional, Goussot, Samuel, additional, Grimard, Caroline, additional, Guichard, Jean-Baptiste, additional, Haissaguerre, Michel, additional, Hamon, David, additional, Hascoet, Sébastien, additional, Hasni, Karim, additional, Hermida, Jean-Sylvain, additional, Hidden-Lucet, Françoise, additional, Hocini, Mélèze, additional, Hourdain, Jérome, additional, Jacon, Peggy, additional, Jauvert, Gaël, additional, Jean, Frédéric, additional, Johnson, Nicolas, additional, Khattar, Pierre, additional, Khoueiry, Ziad, additional, Koutbi, Rita, additional, Laborie, Guillaume, additional, Lactu, Gabriel, additional, Lallemand, Pierre-Marc, additional, Laurent, Gabriel, additional, Lavergne, Thomas, additional, Lazarus, Arnaud, additional, Le Gloan, Laurianne, additional, Leclercq, Christophe, additional, Leenhardt, Antoine, additional, Lellouche, Nicolas, additional, Loose, Christophe, additional, Mabo, Philippe, additional, Maltret, Alice, additional, Mandel, Franck, additional, Marquie, Christelle, additional, Maupain, Carole, additional, Milhelm, Antoine, additional, Milliez, Paul, additional, Mirolo, Adrian, additional, Moubarak, Ghassan, additional, Mourot, Stéphane, additional, Ollitrault, Jacky, additional, Ollitrault, Pierre, additional, Otmani, Akli, additional, Pasquie, Jean-Luc, additional, Pavin, Dominique, additional, Philibert, Séverinne, additional, Poindron, Damien, additional, Potelle, Charlotte, additional, Probst, Vincent, additional, Puie, Paul, additional, Rollin, Anne, additional, Romeyer-Bouchard, Cécile, additional, Sadoul, Nicolas, additional, Sagnard, Audrey, additional, Savoure, Arnaud, additional, Scarlatti, Didier, additional, Squara, Fabien, additional, Tanese, Nikita, additional, Thambo, Jean Benoit, additional, Thomas, Olivier, additional, Varlet, Emie, additional, Venier, Sandrine, additional, Stephanopoli, Quentin Voglimacci, additional, Waintraub, Xavier, additional, Waldmann, Victor, additional, Wiart, Françoise, additional, Zhao, Alexandre, additional, and Zouaghi, Amir, additional

Published
2022
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15. Cardiovascular outcomes after cardiac resynchronization therapy in cardiac amyloidosis

Author

Fischer, Kilian, primary, Lellouche, Nicolas, additional, Damy, Thibaud, additional, Martins, Raphaël, additional, Clementy, Nicolas, additional, Bisson, Arnaud, additional, Lesaffre, François, additional, Espinosa, Madeline, additional, Garcia, Rodrigue, additional, Degand, Bruno, additional, Serzian, Guillaume, additional, Jourda, François, additional, Huttin, Olivier, additional, Guichard, Jean‐Baptiste, additional, Devilliers, Hervé, additional, Eicher, Jean‐Christophe, additional, Laurent, Gabriel, additional, and Guenancia, Charles, additional

Published
2021
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17. Long-term follow-up of patients with tetralogy of fallot and implantable cardioverter defibrillator–The DAI-T4F nationwide registry

Author

Waldmann, Victor, primary, Bouzeman, Abdeslam, additional, Duthoit, Guillaume, additional, Koutbi, Linda, additional, Bessiere, Francis, additional, Labombarda, Fabien, additional, Marquié, Christelle, additional, Gourraud, Jean Baptiste, additional, Mondoly, Pierre, additional, Sellal, Jean-Marc, additional, Bordachar, Pierre, additional, Hermida, Alexis, additional, Anselme, Frédéric, additional, Asselin, Anouk, additional, Audinet, Caroline, additional, Bernard, Yvette, additional, Bru, Paul, additional, Sithikun Bun, Sok, additional, Clerici, Gael, additional, Da Costa, Antoine, additional, de Guillebon, Maxime, additional, Defaye, Pascal, additional, Elbaz, Nathalie, additional, Eschalier, Romain, additional, Garcia, Rodrigue, additional, Guenancia, Charles, additional, Guy-Moyat, Benoit, additional, Halimi, Franck, additional, Irles, Didier, additional, Iserin, Laurence, additional, Jourda, François, additional, Ladouceur, Magalie, additional, Lagrange, Philippe, additional, Laredo, Mikael, additional, Mansourati, Jacques, additional, Massoulié, Grégoire, additional, Mathiron, Amel, additional, Maury, Philippe, additional, Messali, Anne, additional, Narayanan, Kumar, additional, Nguyen, Cédric, additional, Ninni, Sandro, additional, Perier, Marie-Cécile, additional, Pierre, Bertrand, additional, Pujadas, Penelope, additional, Sacher, Frédéric, additional, Sagnol, Pascal, additional, Sharifzadehgan, Ardalan, additional, Walton, Camille, additional, Winum, Pierre, additional, Zakine, Cyril, additional, Fauchier, Laurent, additional, Martins, Raphael, additional, Pasquié, Jean-Luc, additional, Thambo, Jean-Benoit, additional, Jouven, Xavier, additional, Combes, Nicolas, additional, and Marijon, Eloi, additional

Published
2021
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18. Hydroxychloroquine in mild-to-moderate coronavirus disease 2019: a placebo-controlled double blind trial

Author

Dubée, Vincent, primary, Roy, Pierre-Marie, additional, Vielle, Bruno, additional, Parot-Schinkel, Elsa, additional, Blanchet, Odile, additional, Darsonval, Astrid, additional, Lefeuvre, Caroline, additional, Abbara, Chadi, additional, Boucher, Sophie, additional, Devaud, Edouard, additional, Robineau, Olivier, additional, Rispal, Patrick, additional, Guimard, Thomas, additional, d’Anglejean, Emma, additional, Diamantis, Sylvain, additional, Custaud, Marc-Antoine, additional, Pellier, Isabelle, additional, Mercat, Alain, additional, Brangier, Antoine, additional, Codron, Philippe, additional, Lemée, Jean Michel, additional, Pichon, Virginie, additional, Dhersin, Robin, additional, Urbanski, Geoffrey, additional, Lavigne, Christian, additional, Courtois, Roxane, additional, Danielou, Hélène, additional, Lebreton, Jonathan, additional, Vatan, Rémi, additional, Crochette, Nicolas, additional, Lainé, Jean-Baptiste, additional, Perez, Lucia, additional, Blanchi, Sophie, additional, Hitoto, Hikombo, additional, Bernard, Louis, additional, Maillot, François, additional, Marchand Adam, Sylvain, additional, Talarmin, Jean-Philippe, additional, Gaigneux, Emeline, additional, Motte-Vincent, Pauline, additional, Morrier, Marine, additional, Merrien, Dominique, additional, Bleher, Yves, additional, Flori, Maxime, additional, Ducet-Boiffard, Amélie, additional, Colin, Orane, additional, Février, Ronan, additional, Thill, Pauline, additional, Tetart, Macha, additional, Demaeght, François, additional, Lafond-Desmurs, Barthelemy, additional, Pradier, Maxime, additional, Meybeck, Agnes, additional, Picaud, Marjorie, additional, Prazuck, Thierry, additional, Chapelet, Guillaume, additional, Rouaud, Agnès, additional, Le Turnier, Paul, additional, Sunder, Simon, additional, Lorleac'h, Aurélien, additional, Dollon, Christophe, additional, Jacquet, Antoine, additional, Le Vely, Francois, additional, Gazeau, Pierre, additional, Ansart, Séverine, additional, Roger, Hélène, additional, Laterza, François, additional, Buzelé, Rodolphe, additional, Tahmi, Fella, additional, Lepeule, Raphael, additional, Lacombe, Karine, additional, Lefebvre, Bénédicte, additional, Célarier, Thomas, additional, Gagneux-Brunon, Amandine, additional, Botelho-Nevers, Elisabeth, additional, Bernard, Marc, additional, Garnier, Camille, additional, Mourguet, Morgane, additional, Pugnet, Gregory, additional, Vienne-Noyes, Sara, additional, Martin-Blondel, Guillaume, additional, Delobel, Pierre, additional, Grouteau, Gaspard, additional, Debard, Alexa, additional, Guilleminault, Laurent, additional, Arias, Pauline, additional, Chakvetadze, Catherine, additional, Flateau, Clara, additional, Kopp, Aude, additional, Putot, Alain, additional, Barben, Jeremy, additional, Mouries Martin, Suzanne, additional, Nuss, Valentine, additional, Piroth, Lionel, additional, Claessens, Yann-Erick, additional, Hentgen, Veronique, additional, Martinot, Martin, additional, Bach-Bunner, Maxime, additional, Bonijoly, Thomas, additional, Gravier, Simon, additional, Michel, Jean-Marc, additional, Andreu, Mathilde, additional, Roriz, Mélanie, additional, Baldolli, Aurélie, additional, Brochard, Julia, additional, Grossi, Olivier, additional, Pineau, Samuel, additional, Brisset, Josselin, additional, Desvaux, Edouard, additional, Gondran, Guillaume, additional, Faucher, Jean-François, additional, Quesnel, Paul-Antoine, additional, Bezanahary, Holy, additional, Danthu, Clément, additional, Gutierrez, Blandine, additional, Ly, Kim, additional, Simonneau, Yannick, additional, Cypierre, Anne, additional, Pinet, Pauline, additional, Durox, Hélène, additional, Ducroix-Roubertou, Sophie, additional, Genet, Claire, additional, Beraud, Guillaume, additional, Le Moal, Gwenael, additional, Rammaert, Blandine, additional, Lanoix, Jean-Philippe, additional, Andrejak, Claire, additional, Joseph, Cédric, additional, Soriot-Thomas, Sandrine, additional, Dhote, Robin, additional, Abad, Sébastien, additional, Benainous, Ruben, additional, Boitiaux, Jean-François, additional, Briend, Guillaume, additional, Gonfroy, Celine, additional, Harent, Stanislas, additional, Lagrange, Aurore, additional, Tone, Alina, additional, Wayenberg, Laura, additional, Desoutter, Sophie, additional, Ettahar, Nicolas, additional, Gey, Thomas, additional, Leroy, Vincent, additional, Gaillard, Sacha, additional, Toma, Andrea, additional, Broussier, Amaury, additional, Etienne, Sandrine, additional, Spivac, Yann, additional, Martha, Benoit, additional, Roch, Nathalie, additional, Diaz, Pierre, additional, N’guyen Baranoff, Danièle, additional, Rebaudet, Stanislas, additional, Jourda, François, additional, Zeller, Valérie, additional, Bienvenu, Boris, additional, Boyer, Arnaud, additional, Briet, Marie, additional, Dubée, Vincent, additional, Guidet, Bertrand, additional, Mismetti, Patrick, additional, Vicaut, Eric, additional, Sanchez, Olivier, additional, Girard, Philippe, additional, Elias, Antoine, additional, Couturaud, Francis, additional, Gable, Béatrice, additional, Lazareff, Sybille, additional, Carballido, Loïc, additional, Hue, Catherine, additional, Chrétien, Jean-Marie, additional, Goraguer, Adrien, additional, and Eeckhoutte, Lucie van, additional

Published
2021
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19. Relation of outcomes to ABC (Atrial Fibrillation Better Care) pathway adherent care in European patients with atrial fibrillation:an analysis from the ESC-EHRA EORP Atrial Fibrillation General Long-Term (AFGen LT) Registry

Author

Cuisset, Thomas, Fauchier, Laurent, Deharo, Pierre, Cohen, Ariel, Waldmann, Victor, Bouzeman, Abdeslam, Duthoit, Guillaume, Koutbi, Linda, Bessiere, Francis, Labombarda, Fabien, Marquié, Christelle, Gourraud, Jean Baptiste, Mondoly, Pierre, Sellal, Jean Marc, Bordachar, Pierre, Hermida, Alexis, Anselme, Frédéric, Asselin, Anouk, Audinet, Caroline, Bernard, Yvette, Boveda, Serge, Bru, Paul, Bun, Sok Sithikun, Clerici, Gael, da Costa, Antoine, de Guillebon, Maxime, Defaye, Pascal, Elbaz, Nathalie, Eschalier, Romain, Garcia, Rodrigue, Guenancia, Charles, Guy-Moyat, Benoit, Halimi, Franck, Irles, Didier, Iserin, Laurence, Jourda, François, Ladouceur, Magalie, Lagrange, Philippe, Laredo, Mikael, Mansourati, Jacques, Massoulié, Grégoire, Mathiron, Amel, Maury, Philippe, Messali, Anne, Narayanan, Kumar, Nguyen, Cédric, Ninni, Sandro, Perier, Marie-Cécile, Pierre, Bertrand, Pujadas, Penelope, Sacher, Frédéric, Sagnol, Pascal, Sharifzadehgan, Ardalan, Walton, Camille, Winum, Pierre, Zakine, Cyril, Martins, Raphael, Pasquié, Jean Luc, Thambo, Jean Benoit, Jouven, Xavier, Combes, Nicolas, Marijon, Eloi, Squara, Fabien, Theodore, Guillaume, Scarlatti, Didier, Hourdain, Jérome, Deharo, Jean-Claude, Ollitrault, Pierre, Milliez, Paul, Champ-Rigot, Laure, Bader, Hugues, Duplantier, Cécile, Milhem, Antoine, Sagnard, Audrey, Bertaux, Géraldine, Laurent, Gabriel, Badoz, Marc, Bortone, Agustin, Laborie, Guillaume, Rollin, Anne, Stephanopoli, Quentin Voglimacci, Mandel, Franck, Duparc, Alexandre, Domain, Guillaume, Albenque, Jean-Paul, Cardin, Christèle, Combes, Stéphane, Tanese, Nikita, Hasni, Karim, Leclercq, Christophe, Galand, Vincent, Pavin, Dominique, Mabo, Philippe, Behar, Nathalie, Clementy, Nicolas, Loose, Christophe, Otmani, Akli, Venier, Sandrine, Carabelli, Adrien, Jacon, Peggy, Kilani, Mouna Ben, Guichard, Jean Bapstist, Romeyer-Bouchard, Cécile, Le Gloan, Laurianne, Probst, Vincent, Freysz, Luc, Blangy, Hugues, Chillou, Christian De, Sadoul, Nicolas, Khattar, Pierre, Potelle, Charlotte, Jean, Frederic, Puie, Paul, Khoueiry, Ziad, Chevallier, Philippe, Dulac, Arnaud, Filippo, Sylvie Di, Gardey, Kevin, Frey, Pierre, Akret, Chrystelle, Dompnier, Antoine, Maupain, Carole, Waintraub, Xavier, Hidden-Lucet, Françoise, Chastre, Thomas, Gandjbakhch, Estelle, Badenco, Nicolas, Extramiana, Fabrice, Leenhardt, Antoine, Zouaghi, Amir, Algalarrondo, Vincent, Amet, Denis, Varlet, Emilie, Chalbia, Tej, Philibert, Séverine, Ollitrault, Jacky, Lavergne, Thomas, Baudinaud, Pierre, Mirolo, Adrian, Savouré, Arnaud, Godin, Bénédicte, Bertrand, Cathy, Fiorello, Pierre, Johnson, Nicolas, Lallemand, Pierre-Marc, Herminda, Alexis, Hermida, Jean-Sylvain, Degand, Bruno, Bouazzaou, Rim El, Mourot, Stéphane, Goussot, Samuel, Jauvert, Gaël, Lazarus, Arnaud, Grimard, Caroline, Alonso, Christine, Zhao, Alexandre, Thomas, Olivier, Cauchemez, Bruno, Moubarak, Ghassan, Lellouche, Nicolas, Hamon, David, Enache, Bogdan, Lactu, Gabriel, Wiart, Françoise, Geoffroy, Olivier, Poindron, Damien, Maltret, Alice, Raimondo, Cristine, Bonnet, Damien, Hascoët, Sébastien, Derval, Nicolas, Haïssaguerre, Michel, Hocini, Mélèze, Proietti, Marco, Lip, Gregory, Laroche, Cécile, Marin, Francisco, Nabauer, Michael, Potpara, Tatjana, Dan, Gheorghe-Andrei, Kalarus, Zbigniew, Tavazzi, Luigi, Maggioni, Aldo Pietro, Boriani, Giuseppe, Hôpital de la Timone [CHU - APHM] (TIMONE), Nutrition, obésité et risque thrombotique (NORT), Institut National de la Recherche Agronomique (INRA)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), CHU Trousseau [Tours], Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), Éducation Éthique Santé EA 7505 (EES), Université de Tours (UT), Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research (C2VN), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), CHU Saint-Antoine [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Université Paris Cité (UPCité), Paris-Centre de Recherche Cardiovasculaire (PARCC (UMR_S 970/ U970)), Hôpital Européen Georges Pompidou [APHP] (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), Centre Hospitalier de Versailles André Mignot (CHV), CHU Pitié-Salpêtrière [AP-HP], Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Research Unit on Cardiovascular and Metabolic Diseases (ICAN), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Institut de Cardiométabolisme et Nutrition = Institute of Cardiometabolism and Nutrition [CHU Pitié Salpêtrière] (IHU ICAN), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-CHU Pitié-Salpêtrière [AP-HP], Département de Cardiologie [Hôpital de la Timone - APHM], Assistance Publique - Hôpitaux de Marseille (APHM)- Hôpital de la Timone [CHU - APHM] (TIMONE), Hôpital Louis Pradel [CHU - HCL], Hospices Civils de Lyon (HCL), Signalisation, électrophysiologie et imagerie des lésions d’ischémie-reperfusion myocardique (SEILIRM), Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Normandie Université (NU), CHU Caen, Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN), Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Centre hospitalier universitaire de Nantes (CHU Nantes), Service Cardiologie [CHU Toulouse], Pôle Cardiovasculaire et Métabolique [CHU Toulouse], Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), IHU-LIRYC, Université Bordeaux Segalen - Bordeaux 2-CHU Bordeaux [Bordeaux], Centre de recherche Cardio-Thoracique de Bordeaux [Bordeaux] (CRCTB), Université Bordeaux Segalen - Bordeaux 2-CHU Bordeaux [Bordeaux]-Institut National de la Santé et de la Recherche Médicale (INSERM), CHU Amiens-Picardie, Service de cardiologie [CHU Rouen], CHU Rouen, Normandie Université (NU)-Normandie Université (NU)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU), Groupe Hospitalier Bretagne Sud (GHBS), Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon), Clinique Pasteur, Clinique Pasteur [Toulouse], Service de cardiologie, Université de la Méditerranée - Aix-Marseille 2-Assistance Publique - Hôpitaux de Marseille (APHM)- Hôpital de la Timone [CHU - APHM] (TIMONE), Hôpital Pasteur [Nice] (CHU), CHU Saint-Pierre, Università degli Studi di Milano = University of Milan (UNIMI), Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, University of Liverpool, Aalborg University [Denmark] (AAU), EURObservational Research Programme, European Society of Cardiology, Universidad de Murcia, University of Belgrade [Belgrade], Colentina University Hospital, University of Medicine and Pharmacy 'Carol Davila' Bucharest (UMPCD), Silesian Medical University, Katowice, Poland, University Hospital of Ferrara and Maria Cecilia Hospital, Associazione Nazionale Medici Cardiologi Ospedalieri [Firenze] (ANMCO), Università degli Studi di Modena e Reggio Emilia = University of Modena and Reggio Emilia (UNIMORE), UCL - SSS/IREC/MONT - Pôle Mont Godinne, and UCL - (MGD) Service de cardiologie

Subjects
medicine.medical_specialty, Acute coronary syndrome, 030204 cardiovascular system & hematology, Lower risk, [SHS]Humanities and Social Sciences, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, Physiology (medical), Internal medicine, Thromboembolism, Atrial Fibrillation, Care pathway, Medicine, Humans, 030212 general & internal medicine, Registries, Outcomes • Registry, business.industry, Hazard ratio, Anticoagulants, Integrated care, Atrial fibrillation, medicine.disease, Confidence interval, 3. Good health, Stroke, Cohort, Cardiology and Cardiovascular Medicine, business
Abstract

Aims There has been an increasing focus on integrated, multidisciplinary, and holistic care in the treatment of atrial fibrillation (AF). The ‘Atrial Fibrillation Better Care’ (ABC) pathway has been proposed to streamline integrated care in AF. We evaluated the impact on outcomes of an ABC adherent management in a contemporary real-life European-wide AF cohort. Methods and results Patients enrolled in the ESC-EHRA EURObservational Research Programme in AF General Long-Term Registry with baseline data to evaluate ABC criteria and available follow-up data were considered for this analysis. Among the original 11 096 AF patients enrolled, 6646 (59.9%) were included in this analysis, of which 1996 (30.0%) managed as ABC adherent. Patients adherent to ABC care had lower CHA2DS2-VASc and HAS-BLED scores (mean ± SD, 2.68 ± 1.57 vs. 3.07 ± 1.90 and 1.26 ± 0.93 vs. 1.58 ± 1.12, respectively; P Conclusion In a large contemporary cohort of European AF patients, a clinical management adherent to ABC pathway for integrated care is associated with a significant lower risk for cardiovascular events, CV death, and all-cause death.

Published
2021
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23. Use of ADAM‐C and CHA2DS2‐VASc scores to predict complex aortic atheroma after brain ischemia: A prospective observational study

Author

Nicot, Florence, primary, Charbonnel, Clément, additional, Jego, Christophe, additional, Jourda, François, additional, Vinsonneau, Ulric, additional, Garçon, Philippe, additional, Turlotte, Guillaume, additional, Rivière, Jean François, additional, Maurin, Marion, additional, Lubret, Rémy, additional, Meimoun, Patrick, additional, Akret, Chrystelle, additional, Cournot, Maxime, additional, Sokic, Charles, additional, Michel, Laurent, additional, Lescure, Maryse, additional, Kenizou, David, additional, Melay, Marie, additional, Fayard, Maxime, additional, Chauvat, Anthony, additional, Fouché, Renaud, additional, Cartigny, Guillaume, additional, Dijoux, Nicolas, additional, Martin, Anne Céline, additional, Tho‐Agostini, Aurélia, additional, Mann, Hubert, additional, Magnin, Dominique, additional, Goralski, Marc, additional, Pico, Fernando, additional, Georges, Jean‐Louis, additional, and Belle, Loïc, additional

Published
2021
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24. MP-453092-9 PROGNOSTIC SIGNIFICANCE OF SUSTAINED VENTRICULAR ARRHYTHMIAS OCCURRING UNDER WEARABLE CARDIOVERTER DEFIBRILLATOR PROTECTION IN POST-INFARCT PATIENTS WITH A LEFT VENTRICULAR DYSFUNCTION

Author

ECHIVARD, Mathieu, Sellal, Jean-Marc, Ziliox, Chloé, Marijon, Eloi, BORDACHAR, Pierre, marquie, christelle, Docq, Clemence, Eschalier, Romain, Maille, Baptiste, DEHARO, JEAN-CLAUDE, Babuty, Dominique, gandjbakhch, estelle, Da Costa, Antoine, Piot, Olivier, Minois, Damien, GOURRAUD, JEAN BAPTISTE, MONDOLY, PIERRE, Maury, Philippe, BOVEDA, SERGE, Pasquie, Jean-Luc, Martins, Raphael, Leclercq, Christophe, Guenancia, Charles, LAURENT, Gabriel, Becker, Mathieu, BERTRAND, JULIEN, Chevalier, Philippe, Manenti, Vladimir, KUBALA, MACIEJ, DEFAYE, PASCAL, Jacon, Peggy, Desbiolles, Antoine, Badoz, Marc, Jesel, Laurence, Lellouche, Nicolas, Milliez, Paul, Ollitrault, Paul, Fareh, Samir, Bercker, Matthieu, Mansourati, Jacques, Moyat, Benoit Guy, Luconi, Nicolas, Chabert, Jean-Pierre, pierre winum, Anselme, Frederic, Leenhardt, Antoine, Extramiana, Fabrice, Delahaye, Camille, Jourda, François, Bizeau, Olivier, Nasarre, Mathieu, OLIVIER, ARNAUD, Fromentin, Stéphane, VILLEMIN, THIBAULT, Levavasseur, Olivier, Hammache, Néfissa, Magnin, Isabelle, Blangy, Hugues, Sadoul, Nicolas, Duarte, Kévin, Girerd, Nicolas, and de Chillou, Christian

Published
2023
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25. Wearable cardioverter-defibrillator in patients with a transient risk of sudden cardiac death: the WEARIT-France cohort study

Author

Garcia, Rodrigue, primary, Combes, Nicolas, additional, Defaye, Pascal, additional, Narayanan, Kumar, additional, Guedon-Moreau, Laurence, additional, Boveda, Serge, additional, Blangy, Hugues, additional, Bouet, Jérôme, additional, Briand, Florent, additional, Chevalier, Philippe, additional, Cottin, Yves, additional, Da Costa, Antoine, additional, Degand, Bruno, additional, Deharo, Jean-Claude, additional, Eschalier, Romain, additional, Extramiana, Fabrice, additional, Goralski, Marc, additional, Guy-Moyat, Benoit, additional, Guyomar, Yves, additional, Hermida, Jean-Sylvain, additional, Jourda, François, additional, Lellouche, Nicolas, additional, Mahfoud, Mohanad, additional, Manenti, Vladimir, additional, Mansourati, Jacques, additional, Martin, Angéline, additional, Pasquié, Jean-Luc, additional, Ritter, Philippe, additional, Rollin, Anne, additional, Tibi, Thierry, additional, Yalioua, Arab, additional, Gras, Daniel, additional, Sadoul, Nicolas, additional, Piot, Olivier, additional, Leclercq, Christophe, additional, and Marijon, Eloi, additional

Published
2020
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26. Cardiovascular outcomes after cardiac resynchronization therapy in cardiac amyloidosis.

Author

Fischer, Kilian, Lellouche, Nicolas, Damy, Thibaud, Martins, Raphaël, Clementy, Nicolas, Bisson, Arnaud, Lesaffre, François, Espinosa, Madeline, Garcia, Rodrigue, Degand, Bruno, Serzian, Guillaume, Jourda, François, Huttin, Olivier, Guichard, Jean‐Baptiste, Devilliers, Hervé, Eicher, Jean‐Christophe, Laurent, Gabriel, and Guenancia, Charles

Subjects
CARDIAC pacing, CARDIAC amyloidosis
Abstract

Aims: Cardiac resynchronization therapy (CRT) is highly effective in dilated cardiomyopathy (DCM) patients with impaired left ventricular ejection fraction (LVEF) and left bundle block branch. In cardiac amyloidosis (CA) patients, left ventricular dysfunction and conduction defects are common, but the potential of CRT to improve cardiac remodelling and survival in this particular setting remains undefined. We investigated cardiovascular outcomes in CA patients after CRT implantation in terms of CRT echocardiographic response and major cardiovascular events (MACEs). Methods and results: Our retrospective study included 47 CA patients implanted with CRT devices from January 2012 to February 2020, in nine French university hospitals (77 ± 6 years old, baseline LVEF 30 ± 8%) compared with propensity‐matched (1:1 for age, LVEF at implantation, and CRT indication) DCM patients with a CRT device. CA patients had lower rates of CRT response (absolute delta LVEF ≥ 10%) compared with DCM patients (36% vs. 70%, P = 0.002). After multivariate Cox analysis, CA was independently associated with MACE (hospitalization for heart failure/cardiovascular death) [hazard ratio (HR) 3.73, 95% confidence interval (CI) 1.85–7.54, P < 0.001], along with the absence of CRT response (HR 3.01, 95% CI 1.56–5.79, P = 0.001). The presence of echocardiographic CRT response (absolute delta LVEF ≥ 10%) was the only predictive factor of MACE‐free survival in CA patients (HR 0.36, 95% CI 0.15–0.86, P = 0.002). Conclusion: Compared with a matched cohort of DCM patients, CA patients had a lower rate of CRT response and consequently a worse cardiovascular prognosis after CRT implantation. However, CRT could be beneficial even in CA patients given that CRT response was associated with better cardiac outcomes in this population. [ABSTRACT FROM AUTHOR]

Published
2022
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28. Exclusion of Intra-Atrial Thrombus Diagnosis Using D-Dimer Assay Before Catheter Ablation of Atrial Fibrillation

Author

Milhem, Antoine, primary, Ingrand, Pierre, additional, Tréguer, Frédéric, additional, Cesari, Olivier, additional, Da Costa, Antoine, additional, Pavin, Dominique, additional, Rivat, Philippe, additional, Badenco, Nicolas, additional, Abbey, Sélim, additional, Zannad, Noura, additional, Winum, Pierre François, additional, Mansourati, Jacques, additional, Maury, Philippe, additional, Bader, Hugues, additional, Savouré, Arnaud, additional, Sacher, Frédéric, additional, Andronache, Marius, additional, Allix-Béguec, Caroline, additional, De Chillou, Christian, additional, Anselme, Frédéric, additional, Al Arnaout, Alain, additional, Amara, Walid, additional, Amelot, Mathieu, additional, Bars, Clément, additional, Becoulet, Lucile, additional, Bru, Paul, additional, Chevalier, Philippe, additional, Darmon, Jean-Philippe, additional, Deharo, Jean-Claude, additional, Dompnier, Antoine, additional, Duplantier-Duchene, Cécile, additional, Extramiana, Fabrice, additional, Faugier, Jean-Paul, additional, Guenancia, Charles, additional, Horvilleur, Jérôme, additional, Jourda, François, additional, Laurent, Gabriel, additional, Lellouche, Nicolas, additional, Magnin Poull, Isabelle, additional, Piot, Olivier, additional, Roux, Antoine, additional, Saludas, Yannick, additional, Seitz, Julien, additional, and Taieb, Jérôme, additional

Published
2019
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29. ADAM-C score: New risk score for predicting diagnostic yield of transesophageal echocardiography after cerebral ischemia.

Author

Charbonnel, Clément, Jego, Christophe, Jourda, François, Vinsonneau, Ulric, Garçon, Philippe, Turlotte, Guillaume, Rivière, Jean François, Maurin, Marion, Lubret, Rémy, Meimoun, Patrick, Akret, Chrystelle, Cournot, Maxime, Sokic, Charles, Michel, Laurent, Lescure, Maryse, Kenizou, David, Melay, Marie, Fayard, Maxime, Gallet, Bruno, and Fouche, Rémi

Subjects
ALGORITHMS, CEREBRAL ischemia, LONGITUDINAL method, MEDICAL cooperation, SCIENTIFIC observation, RESEARCH, TRANSESOPHAGEAL echocardiography, INDEPENDENT variables
Abstract

Background and aim: The clinical utility of transesophageal echocardiography (TEE) after brain ischemia (BI) remains a matter of debate. We aimed to evaluate the clinical impact of TEE and to build a score that could help physicians to identify which patients should better benefit from TEE. Methods: This prospective, multicenter, observational study included patients over 18 years old, hospitalized for BI. TEE findings were judged discriminant if the results showed important information leading to major changes in the management of patients. Most patients with patent foramen ovale were excluded. Variables independently associated with a discriminant TEE were used to build the prediction model. Results: Of the entire population (1479 patients), 255 patients (17%) were classified in the discriminant TEE group. Five parameters were selected as predictors of a discriminant TEE. Accordingly, the ADAM-C score could be calculated as follows: Score = 4 (if age ≥60) + 2 (if diabetes) + 2 (if aortic stenosis from any degrees) + 1 (if multi-territory stroke) + 2 (if history of coronary artery disease). At a threshold lower than 3, the sensitivity, specificity, positive predictive value, and negative predictive value (NPV) of detecting discriminant TEE were 88% (95% CI 85-90), 44% (95% CI 41-47), 21% (95% CI 19-27), and 95% (95% CI 94-97), respectively. Conclusion: A simple score based on clinical and transthoracic echocardiographic parameters can help physicians to identify patients who might not benefit from TEE. Indeed, a score lower than 3 has an interesting NPV of 95% (95% CI 94-97). [ABSTRACT FROM AUTHOR]

Published
2018
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32. Prognostic value of ventricular arrhythmia in early post-infarction left ventricular dysfunction: the French nationwide WICD-MI study.

Author

Echivard M, Sellal JM, Ziliox C, Marijon E, Bordachar P, Ploux S, Benali K, Marquié C, Docq C, Klug D, Eschalier R, Maille B, Deharo JC, Babuty D, Genet T, Gandjbakhch E, Da Costa A, Piot O, Minois D, Gourraud JB, Mondoly P, Maury P, Boveda S, Pasquié JL, Martins R, Leclercq C, Guenancia C, Laurent G, Becker M, Bertrand J, Chevalier P, Manenti V, Kubala M, Defaye P, Jacon P, Desbiolles A, Badoz M, Jesel L, Lellouche N, Milliez PU, Ollitrault P, Fareh S, Bercker M, Mansourati J, Guy-Moyat B, Chabert JP, Luconi N, Winum PF, Anselme F, Extramiana F, Delahaye C, Jourda F, Bizeau O, Nasarre M, Olivier A, Fromentin S, Villemin T, Levavasseur O, Hammache N, Magnin-Poull I, Blangy H, Sadoul N, Duarte K, Girerd N, and de Chillou C

Subjects
Humans, Male, Female, Retrospective Studies, Prognosis, Aged, Middle Aged, France epidemiology, Stroke Volume physiology, Tachycardia, Ventricular therapy, Tachycardia, Ventricular etiology, Tachycardia, Ventricular physiopathology, Ventricular Dysfunction, Left physiopathology, Ventricular Dysfunction, Left therapy, Ventricular Dysfunction, Left etiology, Myocardial Infarction complications, Myocardial Infarction mortality, Defibrillators, Implantable
Abstract

Background and Aims: Prophylactic implantable cardioverter-defibrillators (ICDs) are not recommended until left ventricular ejection fraction (LVEF) has been reassessed 40 to 90 days after an acute myocardial infarction. In the current therapeutic era, the prognosis of sustained ventricular arrhythmias (VAs) occurring during this early post-infarction phase (i.e. within 3 months of hospital discharge) has not yet been specifically evaluated in post-myocardial infarction patients with impaired LVEF. Such was the aim of this retrospective study., Methods: Data analysis was based on a nationwide registry of 1032 consecutive patients with LVEF ≤ 35% after acute myocardial infarction who were implanted with an ICD after being prescribed a wearable cardioverter-defibrillator (WCD) for a period of 3 months upon discharge from hospital after the index infarction., Results: ICDs were implanted either because a sustained VA occurred while on WCD (VA+/WCD, n = 72) or because LVEF remained ≤35% at the end of the early post-infarction phase (VA-/WCD, n = 960). The median follow-up was 30.9 months. Sustained VAs occurred within 1 year after ICD implantation in 22.2% and 3.5% of VA+/WCD and VA-/WCD patients, respectively (P < .0001). The adjusted multivariable analysis showed that sustained VAs while on WCD independently predicted recurrence of sustained VAs at 1 year (adjusted hazard ratio [HR] 6.91; 95% confidence interval [CI] 3.73-12.81; P < .0001) and at the end of follow-up (adjusted HR 3.86; 95% CI 2.37-6.30; P < .0001) as well as 1-year mortality (adjusted HR 2.86; 95% CI 1.28-6.39; P = .012)., Conclusions: In patients with LVEF ≤ 35%, sustained VA during the early post-infarction phase is predictive of recurrent sustained VAs and 1-year mortality., (© The Author(s) 2024. Published by Oxford University Press on behalf of the European Society of Cardiology. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.)

Published
2024
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33. Beta-Blocker Interruption or Continuation after Myocardial Infarction.

Author

Silvain J, Cayla G, Ferrari E, Range G, Puymirat E, Delarche N, Guedeney P, Cuisset T, Ivanes F, Lhermusier T, Petroni T, Lemesle G, Bresoles F, Labeque JN, Pommier T, Dillinger JG, Leclercq F, Boccara F, Lim P, Besseyre des Horts T, Fourme T, Jourda F, Furber A, Lattuca B, Redjimi N, Thuaire C, Deharo P, Procopi N, Dumaine R, Slama M, Payot L, El Kasty M, Aacha K, Diallo A, Vicaut E, and Montalescot G

Subjects
Aged, Female, Humans, Male, Middle Aged, Drug Administration Schedule, Follow-Up Studies, Hospitalization statistics & numerical data, Kaplan-Meier Estimate, Stroke Volume drug effects, Stroke Volume physiology, Withholding Treatment, Adrenergic beta-Antagonists administration & dosage, Adrenergic beta-Antagonists adverse effects, Myocardial Infarction epidemiology, Myocardial Infarction physiopathology, Myocardial Infarction prevention & control, Myocardial Infarction psychology, Quality of Life, Secondary Prevention methods
Abstract

Background: The appropriate duration of treatment with beta-blocker drugs after a myocardial infarction is unknown. Data are needed on the safety and efficacy of the interruption of long-term beta-blocker treatment to reduce side effects and improve quality of life in patients with a history of uncomplicated myocardial infarction., Methods: In a multicenter, open label, randomized, noninferiority trial conducted at 49 sites in France, we randomly assigned patients with a history of myocardial infarction, in a 1:1 ratio, to interruption or continuation of beta-blocker treatment. All the patients had a left ventricular ejection fraction of at least 40% while receiving long-term beta-blocker treatment and had no history of a cardiovascular event in the previous 6 months. The primary end point was a composite of death, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for cardiovascular reasons at the longest follow-up (minimum, 1 year), according to an analysis of noninferiority (defined as a between-group difference of <3 percentage points for the upper boundary of the two-sided 95% confidence interval). The main secondary end point was the change in quality of life as measured by the European Quality of Life-5 Dimensions questionnaire., Results: A total of 3698 patients underwent randomization: 1846 to the interruption group and 1852 to the continuation group. The median time between the last myocardial infarction and randomization was 2.9 years (interquartile range, 1.2 to 6.4), and the median follow-up was 3.0 years (interquartile range, 2.0 to 4.0). A primary-outcome event occurred in 432 of 1812 patients (23.8%) in the interruption group and in 384 of 1821 patients (21.1%) in the continuation group (risk difference, 2.8 percentage points; 95% confidence interval [CI], <0.1 to 5.5), for a hazard ratio of 1.16 (95% CI, 1.01 to 1.33; P = 0.44 for noninferiority). Beta-blocker interruption did not seem to improve the patients' quality of life., Conclusions: In patients with a history of myocardial infarction, interruption of long-term beta-blocker treatment was not found to be noninferior to a strategy of beta-blocker continuation. (Funded by the French Ministry of Health and ACTION Study Group; ABYSS ClinicalTrials.gov number, NCT03498066; EudraCT number, 2017-003903-23.)., (Copyright © 2024 Massachusetts Medical Society.)

Published
2024
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34. Wearable cardioverter-defibrillator in patients with a transient risk of sudden cardiac death: the WEARIT-France cohort study.

Author

Garcia R, Combes N, Defaye P, Narayanan K, Guedon-Moreau L, Boveda S, Blangy H, Bouet J, Briand F, Chevalier P, Cottin Y, Da Costa A, Degand B, Deharo JC, Eschalier R, Extramiana F, Goralski M, Guy-Moyat B, Guyomar Y, Hermida JS, Jourda F, Lellouche N, Mahfoud M, Manenti V, Mansourati J, Martin A, Pasquié JL, Ritter P, Rollin A, Tibi T, Yalioua A, Gras D, Sadoul N, Piot O, Leclercq C, and Marijon E

Subjects
Aged, Cohort Studies, Death, Sudden, Cardiac epidemiology, Death, Sudden, Cardiac prevention & control, Defibrillators, Electric Countershock, Female, France epidemiology, Humans, Male, Middle Aged, Retrospective Studies, Treatment Outcome, Defibrillators, Implantable, Wearable Electronic Devices
Abstract

Aims: We aimed to provide contemporary real-world data on wearable cardioverter-defibrillator (WCD) use, not only in terms of effectiveness and safety but also compliance and acceptability., Methods and Results: Across 88 French centres, the WEARIT-France study enrolled retrospectively patients who used the WCD between May 2014 and December 2016, and prospectively all patients equipped for WCD therapy between January 2017 and March 2018. All patients received systematic education session through a standardized programme across France at the time of initiation of WCD therapy and were systematically enrolled in the LifeVest Network remote services. Overall, 1157 patients were included (mean age 60 ± 12 years, 16% women; 46% prospectively): 82.1% with ischaemic cardiomyopathy, 10.3% after implantable cardioverter-defibrillator explant, and 7.6% before heart transplantation. Median WCD usage period was 62 (37-97) days. Median daily wear time of WCD was 23.4 (22.2-23.8) h. In multivariate analysis, younger age was associated with lower compliance [adjusted odds ratio (OR) 0.97, 95% confidence interval (CI) 0.95-0.99, P < 0.01]. A total of 18 participants (1.6%) received at least one appropriate shock, giving an incidence of appropriate therapy of 7.2 per 100 patient-years. Patient-response button allowed the shock to be aborted in 35.7% of well-tolerated sustained ventricular arrhythmias and in 95.4% of inappropriate ventricular arrhythmia detection, finally resulting in an inappropriate therapy in eight patients (0.7%)., Conclusion: Our real-life findings reinforce previous studies on the efficacy and safety of the WCD in the setting of transient high-risk group in selected patients. Moreover, they emphasize the fact that when prescribed appropriately, in concert with adequate patient education and dedicated follow-up using specific remote monitoring system, compliance with WCD is high and the device well-tolerated by the patient., (© The Author(s) 2020. Published by Oxford University Press on behalf of the European Society of Cardiology.)

Published
2021
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35. Contact-force guided radiofrequency vs. second-generation balloon cryotherapy for pulmonary vein isolation in patients with paroxysmal atrial fibrillation-a prospective evaluation.

Author

Jourda F, Providencia R, Marijon E, Bouzeman A, Hireche H, Khoueiry Z, Cardin C, Combes N, Combes S, Boveda S, and Albenque JP

Subjects
Aged, Female, Fluoroscopy, Humans, Male, Middle Aged, Operative Time, Prospective Studies, Radiation Dosage, Treatment Outcome, X-Rays, Atrial Fibrillation surgery, Catheter Ablation methods, Cryosurgery methods, Pulmonary Veins surgery
Abstract

Aims: In the setting of paroxysmal atrial fibrillation (AF), there are no available data comparing the mid-term outcome of patients undergoing pulmonary vein isolation (PVI) catheter ablation using contact-force (CF)-guided radiofrequency (RF) vs. second-generation balloon cryotherapy., Methods and Results: Prospective single-centre evaluation, carried out from March 2011 to February 2013, comparing CF radiofrequency (Thermocool(®) SmartTouch™, Biosense Webster, Inc.) (CF group) with cryoballoon ablation (Arctic Front Advance™ 28 mm cryoballoon, Medtronic, Inc.) (CB group), in regards to procedural safety and efficacy, as well as recurrence at 12 months. Overall, 150 consecutive patients were enrolled (75 in each group). The characteristics of patients of both the groups were similar (61.2 ± 9.9 years, women 25.3%, mean AF duration 4.1 ± 4.0 years, mean CHA2DS2-VASc score 1.4 ± 1.3, mean HAS-BLED 1.4 ± 0.6). Duration of the procedure was significantly lower in the CF group (110.7 ± 32.5 vs. 134.5 ± 48.3 min, P = 0.001), with a lower duration of fluoroscopy (21.5 ± 8.5 vs. 25.3 ± 9.9 min, P = 0.017) and X-ray exposure (4748 ± 2411 cGy cm² vs. 7734 ± 5361 cGy cm², P = 0.001). In contrast, no significant difference was found regarding significant procedural complication (2.7 vs. 1.3% in CF and CB groups, respectively; P = 0.56), and PVI was eventually achieved in all cases. At 12 months, AF recurrence occurred in 11 patients (14.7%) in the CB group and in 9 patients (12.0%) in the CF group (HR = 1.20 95% CI 0.50-2.90; log rank P = 0.682)., Conclusions: Our preliminary findings suggest that CF-guided radiofrequency and cryotherapy present very similar performances in the setting of paroxysmal AF catheter ablation., (Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2014. For permissions please email: journals.permissions@oup.com.)

Published
2015
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36. Higher contact-force values associated with better mid-term outcome of paroxysmal atrial fibrillation ablation using the SmartTouch™ catheter.

Author

Providência R, Marijon E, Combes S, Bouzeman A, Jourda F, Khoueiry Z, Cardin C, Combes N, Boveda S, and Albenque JP

Subjects
Catheter Ablation adverse effects, Catheter Ablation methods, Equipment Design, Equipment Failure Analysis, Female, Humans, Male, Middle Aged, Stress, Mechanical, Surgery, Computer-Assisted adverse effects, Touch, Treatment Outcome, User-Computer Interface, Atrial Fibrillation diagnosis, Atrial Fibrillation surgery, Body Surface Potential Mapping instrumentation, Catheter Ablation instrumentation, Surgery, Computer-Assisted instrumentation
Abstract

Aims: Real-time measurement of contact force (CF) during catheter ablation of atrial fibrillation (AF) has been recently suggested to potentially impact procedural outcome. However, the role of CF intensity on mid-term results using the SmartTouch™ catheter has not been investigated so far., Methods and Results: Pulmonary vein isolation (PVI) using the SmartTouch™ catheter was performed in 100 eligible patients (age 62 ± 8; 79% men) undergoing a first procedure of paroxysmal AF catheter ablation. Continuous CF monitoring during catheter ablation allowed calculation of mean CF per patient. Patients were dichotomized into high CF (≥22 g, upper quartile) and low CF (<22 g, remaining) and enroled in a standardized follow-up programme (after a 3-month blanking period), free from antiarrhythmic therapy, with regular evaluations including 24 h Holter recordings at 1, 3, 6, 9, 12, 18, and 24 months. Atrial fibrillation relapse was defined as any symptomatic or asymptomatic atrial arrhythmia lasting >30 s. The average CF among all procedures was 19.6 ± 3.7 g. Though complete PVI was eventually achieved in all cases in both groups, success using an exclusively anatomical approach was higher in the high CF group (92.0 vs. 72.0%; P = 0.04). During a mean follow-up of 19 ± 5 months, a lower incidence of AF relapse was observed in higher CF patients (4.0 vs. 20.0%; log rank P = 0.04). Pericardial tamponade occurred in one patient in the higher CF group. No thromboembolism or procedure-associated deaths were observed., Conclusion: Higher values of CF overall during antral PVI appear to be associated with a higher likelihood of sinus rhythm maintenance without significantly increasing the complication rate., (Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2014. For permissions please email: journals.permissions@oup.com.)

Published
2015
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