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151 results on '"Joshua M. Shulman"'

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1. Integrated analysis of the aging brain transcriptome and proteome in tauopathy

2. Targeted Quantification of Detergent-Insoluble RNA-Binding Proteins in Human Brain Reveals Stage and Disease Specific Co-aggregation in Alzheimer’s Disease

3. Meta-Analysis of the Alzheimer’s Disease Human Brain Transcriptome and Functional Dissection in Mouse Models

4. Drosophila and genome-wide association studies: a review and resource for the functional dissection of human complex traits

5. Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer’s Disease

6. cindr, the Drosophila Homolog of the CD2AP Alzheimer’s Disease Risk Gene, Is Required for Synaptic Transmission and Proteostasis

7. Progress toward an integrated understanding of Parkinson's disease [version 1; referees: 2 approved]

8. Tau polarizes an aging transcriptional signature to excitatory neurons and glia

9. Functional screening of lysosomal storage disorder genes identifies modifiers of alpha-synuclein neurotoxicity.

11. Integration of transcriptome-wide association study with neuronal dysfunction assays provides functional genomics evidence for Parkinson’s disease genes

12. New insights into the genetic etiology of Alzheimer's disease and related dementias

14. Cell‐specific responses to Tau pathology in the aging brain

16. 'Hablemos de Alzheimer': Words Mexican Americans use to talk about Alzheimer’s disease genetic testing. Implications for precision medicine education

17. Tau polarizes an aging transcriptional signature to excitatory neurons and glia

18. Latent factor in Brain RNA-seq studies reflects cell type and clinical heterogeneity

19. Identification of risk genes for Alzheimer's disease by gene embedding

20. In Alzheimer-prone brain regions, metabolism and risk-gene expression are strongly correlated

21. Proteomic Profiling of the Substantia Nigra to Identify Determinants of Lewy Body Pathology and Dopaminergic Neuronal Loss

22. Frequency of Parkinsonism and Parkinson Disease in African Americans in the Chicago Community

23. Functional screening of lysosomal storage disorder genes identifies modifiers of alpha-synuclein mediated neurodegeneration

24. Notes from the Field: Illicit Benzodiazepines Detected in Patients Evaluated in Emergency Departments for Suspected Opioid Overdose — Four States, October 6, 2020–March 9, 2021

25. Drug-specific risk of severe QT prolongation following acute drug overdose

26. Integrating multimodal data to support Alzheimer’s disease target prioritization

29. Genome Sequencing in the Parkinson Disease Clinic

30. Genome sequencing in the Parkinson’s disease clinic

31. Contemporary Characteristics and Lethality Correlates of Serious Suicide Attempts in Children and Adolescents

32. Quantitative mobility metrics from a wearable sensor predict incident parkinsonism in older adults

33. cindr, the Drosophila Homolog of the CD2AP Alzheimer’s Disease Risk Gene, Is Required for Synaptic Transmission and Proteostasis

34. Parkinson's disease age at onset genome‐wide association study: Defining heritability, genetic loci, and α‐synuclein mechanisms

35. Emerging links between pediatric lysosomal storage diseases and adult parkinsonism

36. Integrated analysis of the aging brain transcriptome and proteome in tauopathy

37. Quantitative mobility measures complement the MDS-UPDRS for characterization of Parkinson's disease heterogeneity

38. Meta-Analysis of the Alzheimer’s Disease Human Brain Transcriptome and Functional Dissection in Mouse Models

39. Genome-Wide Association Study Meta-Analysis for Parkinson’s Disease Motor Subtypes

40. TBK1 interacts with tau and enhances neurodegeneration in tauopathy

41. Quantifying cognitive resilience in Alzheimer's Disease: The Alzheimer's Disease Cognitive Resilience Score

43. Ochronosis Presenting as Methemoglobinemia

44. Susceptibility to neurofibrillary tangles: role of the PTPRD locus and limited pleiotropy with other neuropathologies

45. Integrated sequencing and array comparative genomic hybridization in familial Parkinson disease

46. Trends in gabapentin and baclofen exposures reported to U.S. poison centers

47. Integrated Sequencing & Array Comparative Genomic Hybridization in Familial Parkinson’s Disease

48. A Consensus Proteomic Analysis of Alzheimer’s Disease Brain and Cerebrospinal Fluid Reveals Early Changes in Energy Metabolism Associated with Microglia and Astrocyte Activation

49. Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation

50. Retromer subunit, VPS29, regulates synaptic transmission and is required for endolysosomal function in the aging brain

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