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1. Ulcerative colitis mucosal transcriptomes reveal mitochondriopathy and personalized mechanisms underlying disease severity and treatment response

2. Antibodies‐to‐infliximab accelerate clearance while dose intensification reverses immunogenicity and recaptures clinical response in paediatric Crohn’s disease

3. Stratification of risk of progression to colectomy in ulcerative colitis via measured and predicted gene expression

4. Real world population pharmacokinetic study in children and young adults with inflammatory bowel disease discovers novel blood and stool microbial predictors of vedolizumab clearance

5. Serum Protein Biomarkers of Fibrosis Aid in Risk Stratification of Future Stricturing Complications in Pediatric Crohn's Disease

6. Prioritizing Crohn’s disease genes by integrating association signals with gene expression implicates monocyte subsets

7. Stratification of Risk of Progression to Colectomy in Ulcerative Colitis using Measured and Predicted Gene Expression

8. Association of Baseline Luminal Narrowing With Ileal Microbial Shifts and Gene Expression Programs and Subsequent Transmural Healing in Pediatric Crohn Disease

10. Real-World Infliximab Pharmacokinetic Study Informs an Electronic Health Record-Embedded Dashboard to Guide Precision Dosing in Children with Crohn's Disease

11. Mucosal Inflammatory and Wound Healing Gene Programs Reveal Targets for Stricturing Behavior in Pediatric Crohn's Disease

12. Endoscopic Removal of a Single, Painless, Juvenile Polyp in the Small Intestine Causing Anemia

13. Analysis of Using the Total White Blood Cell Count to Define Severe New-onset Ulcerative Colitis in Children

14. Achieving Target Infliximab Drug Concentrations Improves Blood and Fecal Neutrophil Biomarkers in Crohn's Disease

15. Natural History of Very Early Onset Inflammatory Bowel Disease in North America: A Retrospective Cohort Study

16. The Effect of Early-Life Environmental Exposures on Disease Phenotype and Clinical Course of Crohn's Disease in Children

17. Genetic and Transcriptomic Variation Linked to Neutrophil Granulocyte–Macrophage Colony-Stimulating Factor Signaling in Pediatric Crohn’s Disease

18. Clinical and Genomic Correlates of Neutrophil Reactive Oxygen Species Production in Pediatric Patients With Crohn’s Disease

19. Evolution of Pediatric Inflammatory Bowel Disease Unclassified (IBD-U): Incorporated With Serological and Gene Expression Profiles

20. Moving On: Transition Readiness in Adolescents and Young Adults With IBD

21. MACHINE LEARNING FOR CROHN’S DISEASE PHENOTYPE MODELING USING BIOPSY IMAGES

22. Age-of-diagnosis dependent ileal immune intensification and reduced alpha-defensin in older versus younger pediatric Crohn Disease patients despite already established dysbiosis

23. Ulcerative colitis mucosal transcriptomes reveal mitochondriopathy and personalized mechanisms underlying disease severity and treatment response

24. Variation in care in the management of children with Crohn's disease: Data from a multicenter inception cohort study

25. Su519 SHOTGUN METAGENOMICS IDENTIFIES MICROBIAL SIGNATURE CHANGES ASSOCIATED WITH INDUCTION INFLIXIMAB CLEARANCE IN CROHN'S DISEASE

27. 935 PRE-TREATMENT MUCOSAL INFLAMMATORY AND WOUND HEALING GENE PROGRAMS REVEAL MECHANISMS ASSOCIATED WITH FUTURE STRICTURING BEHAVIOR DURING FIVE YEAR FOLLOW-UP IN PEDIATRIC CROHN'S DISEASE

28. 613 ANTIBODIES TO INFLIXIMAB ACCELERATE DRUG CLEARANCE WHILE INTENSIFICATION STRATEGIES REVERSE IMMUNOGENICITY AND RECAPTURE CLINICAL RESPONSE

29. 22 CHANGE IN FECAL CALPROTECTIN AND LACTOFERRIN PREDICT CLINICAL REMISSION FOLLOWING INDUCTION THERAPY WITH INFLIXIMAB IN PEDIATRIC CROHN’S DISEASE (CD)

30. Blood-Derived DNA Methylation Signatures of Crohn's Disease and Severity of Intestinal Inflammation

31. Enhanced Contribution of HLA in Pediatric Onset Ulcerative Colitis

32. Long ncRNA Landscape in the Ileum of Treatment-Naive Early-Onset Crohn Disease

33. Trajectories of oral medication adherence in youth with inflammatory bowel disease

34. Factors associated with early outcomes following standardised therapy in children with ulcerative colitis (PROTECT): a multicentre inception cohort study

35. Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study

36. 27 CLINICAL AND GENOMIC CORRELATES OF NEUTROPHIL GRANULOCYTE-MACROPHAGE COLONY STIMULATING FACTOR SIGNALING IN PEDIATRIC CROHN DISEASE

37. Tu1756 – The Treatment Naive Rectal Transcriptome Identifies Pathways Underlying Response to Induction Corticosteroid Therapy in Ulcerative Colitis

38. 204 – Surgery in Very Early Onset Inflammatory Bowel Disease (Veoibd): Results from a Large, Multi-Center North American Cohort

39. Su1795 – Utilization of Anti-TNF Therapy (BIOLOGICS) in Children with Very Early Onset Inflammatory Bowel Disease (Veoibd) in a Large North American Cohort

40. Mucosal Expression of Type 2 and Type 17 Immune Response Genes Distinguishes Ulcerative Colitis From Colon-Only Crohn's Disease in Treatment-Naive Pediatric Patients

41. Paneth cell defects in Crohn’s disease patients promote dysbiosis

42. Feeling Fine: Anxiety and Depressive Symptoms in Youth with Established IBD

43. Identifying Youth Nonadherence in Clinical Settings: Data-based Recommendations for Children and Adolescents with Inflammatory Bowel Disease

44. Microbial Dysbiosis Associated with Disease Severity in Treatment Naive Pediatric Patients with New-Onset Ulcerative Colitis

45. Predicting Response to Mesalamine Induction Therapy in Children Newly Diagnosed with Mild-to-Moderate Ulcerative Colitis: The Protect Study

46. Predicting Response to Oral Corticosteroid Induction Therapy in Children Newly Diagnosed with Moderately Active Ulcerative Colitis: The Protect Study

47. Corticosteroids Increase Protein Breakdown and Loss in Newly Diagnosed Pediatric Crohn Disease

48. Compositional and Temporal Changes in the Gut Microbiome of Pediatric Ulcerative Colitis Patients Are Linked to Disease Course

49. 378 - Genomic Correlates of Reduced Neutrophil Granulocytemacrophage Colony Stimulating Factor Signaling in Stricturing Pediatric Crohn Disease

50. Su2018 - Longitudinal Adherence to Mesalamine in Pediatric Ulcerative Colitis: Results from the Protect Study

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