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Objective To evaluate resource allocation and costs associated with delivery of human Immunodeficiency virus (HIV) services In Uganda and the United Republic of Tanzania. Methods We used time-driven activity-based costing to determine the resources consumed and costs of providing five HIV services in Uganda and the United Republic of Tanzania: antiretroviral therapy (ART); HIV testing and counselling; prevention of mother-to-child transmission; voluntary male medical circumcision; and pre-exposure prophylaxis. Findings Country-based teams undertook time-driven activity-based costing with 1119 adults in Uganda and 886 adults in the United Republic of Tanzania. In Uganda, service delivery costs ranged from 8.18 United States dollars (US$) per visit for HIV testing and counselling to US$ 43.43 for ART (for clients in whom HIV was suppressed). In the United Republic of Tanzania, these costs ranged from US$ 3.67 per visit for HIV testing and counselling to US$ 28.00 for voluntary male medical circumcision. In both countries, consumables were the main cost driver, accounting for more than 60% of expenditure. Process maps showed that in both countries, registration, measurement of vital signs, consultation and medication dispensing were the steps that occurred most frequently for ART clients. Conclusion Establishing a rigorous, longitudinal system for tracking investments in HIV services that includes thousands of clients and numerous facilities is achievable in different settings with a high HIV burden. Consistent engagement of implementation partners and standardized training and data collection instruments proved essential for the success of these exercises. Objectif Analyser l'allocation des ressources et les couts lies a la fourniture de services de prise en charge du virus de l'immunodeficience humaine (VIH) en Ouganda et en Republique-Unie de Tanzanie. Methodes Nous avons utilise un systeme de calcul des couts par activite pilote par le temps (TDABC), pour identifier les ressources consommees et les couts engendres par cinq services de prise en charge du VIH en Ouganda et en Republique-Unie de Tanzanie: le traitement antiretroviral (TAR); le depistage du VIH et les conseils en la matiere; la prevention de la transmission de la mere a l'enfant; la pratique volontaire de la circoncision masculine medicalisee; et enfin, la prophylaxie preexposition. Resultats Des equipes deployees dans chaque pays ont mene un calcul des couts par activite pilote par le temps aupres de 1119 adultes en Ouganda et 886 adultes en Republique-Unie de Tanzanie. En Ouganda, les couts de prestation des services etaient compris entre 8,18 dollars americains (USD) par visite de depistage du VIH et de conseils en la matiere, et 43,43 USD pour un TAR (sur les patients chez qui la charge virale a ete supprimee). En Republique-Unie de Tanzanie, ces couts variaient entre 3,67 USD par visite de depistage du VIH et de conseils en la matiere a 28,00 USD pour la pratique volontaire de la circoncision masculine medicalisee. Dans les deux pays, les consommables representaient le principal facteur de cout, avec plus de 60% des depenses. Les schemas de procedure ont montre que, dans les deux pays, l'enregistrement, la mesure des signes vitaux, la consultation et l'administration du traitement constituaient les etapes les plus frequentes chez les patients faisant l'objet d'un TAR. Conclusion Il est possible d'etablir un dispositif longitudinal rigoureux pour suivre les investissements realises dans les services de prise en charge du VIH, qui inclut des milliers de patients et de nombreux etablissements dans differents endroits fortement touches par le VIH. Limplication constante des partenaires de mise en oeuvre et la standardisation des formations et instruments de collecte des donnees se sont revelees essentielles a la reussite de ces demarches. Objetivo Analizar la asignacion de recursos y los costes asociados a la prestacion de servicios por el virus de la inmunodeficiencia humana (VIH) en Uganda y en la Republica Unida de Tanzania. Metodos Utilizamos los costes basados en el tiempo invertido por actividad, con el fin de determinar los recursos consumidos y los costes de la prestacion de cinco servicios por VIH en Uganda y en la Republica Unida de Tanzania: terapia antirretroviral (TAR); pruebas y asesoramiento sobre el VIH; prevencion de la transmision de madre a hijo; circuncision medica masculina de caracter voluntario y profilaxis previa a la exposicion. Resultados Los equipos fundados en el pais se encargaron de analizar los costes basados en el tiempo invertido por actividad con 1119 adultos en Uganda y 886 adultos en la Republica Unida de Tanzania. En Uganda, los costes por la prestacion de servicios oscilaron entre 8,18 dolares estadounidenses (USD) por visita destinada a pruebas y asesoramiento sobre VIH, y 43,43 USD por TAR (para clientes en los que se habia erradicado el VIH). En la Republica Unida de Tanzania, estos costes estuvieron comprendidos entre 3,67 USD por visita destinada a pruebas y asesoramiento sobre VIH, y 28,00 USD por circuncision medica masculina de caracter voluntario. En ambos paises, los consumibles fueron los principales generadores de costes, representando mas del 60% del gasto. Los mapas de procesos mostraron que en ambos paises el registro, la medicion de las constantes vitales, asi como las consultas y la dispensacion de medicacion fueron los pasos que mas se repitieron entre los clientes con TAR. Conclusion Implantar un sistema riguroso y longitudinal para realizar un seguimiento de las inversiones en servicios por VIH, lo que engloba a miles de clientes y numerosas instalaciones, es algo que se puede lograr en aquellos centros con una elevada incidencia de VIH. Quedo demostrado que el compromiso constante de los socios encargados de la implementacion, asi como la existencia de instrumentos estandarizados de formacion y de recopilacion de datos resultaban esenciales para el exito de estos ejercicios., Introduction Despite evolving epidemiological trends, human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS) are still responsible for one of the largest disease burdens in sub-Saharan Africa. (1) In low-income [...]

The United States President's Emergency Plan for AIDS Relief (PEPFAR) has been credited with saving millions lives and helping to change the trajectory of the global human immunodeficiency virus (HIV) epidemic. This study assesses whether PEPFAR has had impacts beyond health by examining changes in five economic and educational outcomes in PEPFAR countries: the gross domestic product (GDP) per capita growth rate; the share of girls and share of boys, respectively, who are out of school; and female and male employment rates. We constructed a panel data set for 157 low- and middle-income countries between 1990 and 2018 to estimate the macroeconomic impacts of PEPFAR. Our PEPFAR group included 90 countries that had received PEPFAR support over the period. Our comparison group included 67 low- and middle-income countries that had not received any PEPFAR support or had received minimal PEPFAR support (<$1M or <$.05 per capita) between 2004 and 2018. We used differences in differences (DID) methods to estimate the program impacts on the five economic and educational outcome measures. This study finds that PEPFAR is associated with increases in the GDP per capita growth rate and educational outcomes. In some models, we find that PEPFAR is associated with reductions in male and female employment. However, these effects appear to be due to trends in the comparison group countries rather than programmatic impacts of PEPFAR. We show that these impacts are most pronounced in COP countries receiving the highest levels of PEPFAR investment. [ABSTRACT FROM AUTHOR]

For over 25 years, new programs to attempt to stem the HIV epidemic have been developed in Africa by country governments as well as external donors. These programs and activities have built and operated facilities, trained clinicians, financed drugs and commodities, supported and helped finance government health planning and operations, and contributed in other ways. Who has benefited from this massive mobilization? While some single country and narrowly focused studies have been done, the issue of equity of HIV programs for vulnerable populations has not been examined in a large set of countries. Using Population-based HIV Impact Assessment (PHIA) data, we examine equity of the HIV programs in 13 African countries to determine if vulnerable groups (such as those with low wealth, rural populations, young adults, and females) have achieved comparable levels of access to HIV program services. In contrast, we also compare the equity of the HIV response to rural and low-wealth populations with the equity of corresponding domestic health systems using Demographic and Health Survey data. This study found that in over half of the countries, the HIV response indicators were equitable for vulnerable population segments including the low-wealth population (in seven countries) and rural population segment (in nine countries). In no country was the domestic health system equitable for these two groups. However, HIV programming does show some clear patterns of inequity for low-wealth and rural populations in some countries. For gender and young adults, the HIV response indicators show that in all 13 countries men and young adults are consistently underserved relative to their counterparts. [ABSTRACT FROM AUTHOR]

Using a self-report questionnaire we have determined the prevalence of non-therapeutic drug taking among young persons, within the age range 16-24, in the following groups: school pupils, university/college students, trainee nurses, patients attending special (V.D.) clinics, casualty patients, and young offenders. The percentage proportions of occasional and regular drug misusers within each coup are given together with information on the extent of misuse of individual drugs and drug combinations. [ABSTRACT FROM AUTHOR]

Competing Interests: None.