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4. Measurement of hadron production in <math display='inline'><mrow><msup><mrow><mi>π</mi></mrow><mrow><mo>-</mo></mrow></msup><mtext>-</mtext><mi mathvariant='normal'>C</mi></mrow></math> interactions at 158 and <math display='inline'><mrow><mn>350</mn><mtext> </mtext><mtext> </mtext><mi>GeV</mi><mo>/</mo><mi>c</mi></mrow></math> with NA61/SHINE at the CERN SPS

Author

Adhikary, H., Allison, K.K., Amin, N., Andronov, E.V., Antićić, T., Arsene, I.-C., Balkova, Y., Baszczyk, M., Battaglia, D., Bhosale, S., Blondel, A., Bogomilov, M., Bondar, Y., Bostan, N., Brandin, A., Bravar, A., Bryliński, W., Brzychczyk, J., Buryakov, M., Ćirković, M., Csanad, M., Cybowska, J., Czopowicz, T., Dalmazzone, C., Damyanova, A., Davis, N., Dembinski, H., Dmitriev, A., Dominik, W., Dorosz, P., Dumarchez, J., Engel, R., Feofilov, G.A., Fields, L., Fodor, Z., Friend, M., Garibov, A., Gaździcki, M., Golosov, O., Golovatyuk, V., Golubeva, M., Grebieszkow, K., Guber, F., Haesler, A., Haug, M., Igolkin, S.N., Ilieva, S., Ivashkin, A., Izvestnyy, A., Johnson, S.R., Kadija, K., Kargin, N., Karpushkin, N., Kashirin, E., Kiełbowicz, M., Kireyeu, V.A., Kitagawa, H., Kolesnikov, R., Kolev, D., Korzenev, A., Koshio, Y., Kovalenko, V.N., Kowalski, S., Kozłowski, B., Krasnoperov, A., Kucewicz, W., Kuchowicz, M., Kuich, M., Kurepin, A., László, A., Lewicki, M., Lykasov, G., Lyubushkin, V.V., Maćkowiak-Pawłowska, M., Mariş, I.C., Majka, Z., Makhnev, A., Maksiak, B., Malakhov, A.I., Marcinek, A., Marino, A.D., Marton, K., Mathes, H.-J., Matulewicz, T., Matveev, V., Melkumov, G.L., Merzlaya, A., Merzlaya, A.O., Messerly, B., Mik, L., Morawiec, A., Morozov, S., Nagai, Y., Nakadaira, T., Naskręt, M., Nishimori, S., Ozvenchuk, V., Panova, O., Paolone, V., Petukhov, O., Pidhurskyi, I., Płaneta, R., Podlaski, P., Popov, B.A., Porfy, B., Posiadała-Zezula, M., Prado, R.R., Prokhorova, D.S., Pszczel, D., Puławski, S., Puzović, J., Ravonel, M., Renfordt, R., Röhrich, D., Rondio, E., Roth, M., Rozpłochowski, L., Rumyantsev, M., Ruprecht, M., Rustamov, A., Rybczynski, M., Rybicki, A., Sakashita, K., Schmidt, K., Seryakov, A.Yu., Seyboth, P., Shiraishi, Y., Słodkowski, M., Staszel, P., Stefanek, G., Stepaniak, J., Strikhanov, M., Ströbele, H., Šuša, T., Szuba, M., Szukiewicz, R., Taranenko, A., Tefelska, A., Tefelski, D., Tereshchenko, V., Toia, A., Tsenov, R., Turko, L., Tveter, T.S., Ulrich, R., Unger, M., Urbaniak, M., Valiev, F.F., Veberič, D., Vechernin, V.V., Volkov, V., Wickremasinghe, A., Wójcik, K., Wyszyński, O., Zaitsev, A., Zimmerman, E.D., Zviagina, A., and Zwaska, R.

Subjects
astro-ph.HE, Astrophysics and Astronomy, Nuclear Physics - Experiment, nucl-ex
Abstract

We present a measurement of the momentum spectra of π±, K±, p±, Λ, Λ¯, and KS0 produced in interactions of negatively charged pions with carbon nuclei at beam momenta of 158 and 350 GeV/c. The total production cross sections are measured as well. The data were collected with the large-acceptance spectrometer of the fixed target experiment NA61/SHINE at the CERN SPS. The obtained double-differential p-pT spectra provide a unique reference dataset with unprecedented precision and large phase-space coverage to tune models used for the simulation of particle production in extensive air showers in which pions are the most numerous projectiles. We present a measurement of the momentum spectra of $\pi^\pm$, K$^\pm$, p$^\pm$, $\Lambda$, $\bar{\Lambda}$ and K$^{0}_{S}$ produced in interactions of negatively charged pions with carbon nuclei at beam momenta of 158 and 350 GeV/c. The total production cross sections are measured as well. The data were collected with the large-acceptance spectrometer of the fixed target experiment NA61/SHINE at the CERN SPS. The obtained double-differential $p$-$p_T$ spectra provide a unique reference data set with unprecedented precision and large phase-space coverage to tune models used for the simulation of particle production in extensive air showers in which pions are the most numerous projectiles.

Published
2022

5. Biological and clinical insights from a randomized phase 2 study of an anti-oncostatin M monoclonal antibody in systemic sclerosis

Author

Denton, C.P., Galdo, F. Del, Khanna, D., Vonk, M.C., Chung, L., Johnson, S.R., Varga, J., Furst, D.E., Temple, J., Zecchin, C., Csomor, E., Lee, A, Wisniacki, N., Flint, S.M., Reid, J., Denton, C.P., Galdo, F. Del, Khanna, D., Vonk, M.C., Chung, L., Johnson, S.R., Varga, J., Furst, D.E., Temple, J., Zecchin, C., Csomor, E., Lee, A, Wisniacki, N., Flint, S.M., and Reid, J.

Abstract

Item does not contain fulltext, OBJECTIVES: The cytokine oncostatin M (OSM) is implicated in the pathology of SSc. Inhibiting OSM signalling using GSK2330811 (an anti-OSM monoclonal antibody) in patients with SSc has the potential to slow or stop the disease process. METHODS: This multicentre, randomized, double-blind, placebo-controlled study enrolled participants ≥18 years of age with active dcSSc. Participants were randomized 3:1 (GSK2330811:placebo) in one of two sequential cohorts to receive GSK2330811 (cohort 1: 100 mg; cohort 2: 300 mg) or placebo s.c. every other week for 12 weeks. The primary endpoint was safety; blood and skin biopsy samples were collected to explore mechanistic effects on inflammation and fibrosis. Clinical efficacy was an exploratory endpoint. RESULTS: Thirty-five participants were randomized to placebo (n = 8), GSK2330811 100 mg (n = 3) or GSK2330811 300 mg (n = 24). Proof of mechanism, measured by coordinate effects on biomarkers of inflammation or fibrosis, was not demonstrated following GSK2330811 treatment. There were no meaningful differences between GSK2330811 and placebo for any efficacy endpoints. The safety and tolerability of GSK2330811 were not favourable in the 300 mg group, with on-target, dose-dependent adverse events related to decreases in haemoglobin and platelet count that were not observed in the 100 mg or placebo groups. CONCLUSION: Despite a robust and novel experimental medicine approach and evidence of target engagement, anticipated SSc-related biologic effects of GSK2330811 were not different from placebo and safety was unfavourable, suggesting OSM inhibition may not be a useful therapeutic strategy in SSc. TRIAL REGISTRATION NUMBER: ClinicalTrials.gov, NCT03041025; EudraCT, 2016-003417-95.

Published
2022

6. Measurements of $K^0_{\textrm{S}}$, $\Lambda$ and $\bar{\Lambda}$ production in 120 GeV/$c$ p + C interactions

Author

Adhikary, H., Allison, K.K., Amin, N., Andronov, E.V., Antićić, T., Arsene, I.-C., Balkova, Y., Baszczyk, M., Battaglia, D., Bhosale, S., Blondel, A., Bogomilov, M., Bondar, Y., Bostan, N., Brandin, A., Bravar, A., Bryliński, W., Brzychczyk, J., Buryakov, M., Camino, A., Ćirković, M., Csanad, M., Cybowska, J., Czopowicz, T., Dalmazzone, C., Damyanova, A., Davis, N., Dembinski, H., Dmitriev, A., Haug, M., Mariş, I.C., von Doetinchem, P., Dominik, W., Dorosz, P., Dumarchez, J., Engel, R., Feofilov, G.A., Fields, L., Fodor, Z., Friend, M., Garibov, A., Gaździcki, M., Golosov, O., Golovatyuk, V., Golubeva, M., Grebieszkow, K., Guber, F., Haesler, A., Igolkin, S.N., Ilieva, S., Ivashkin, A., Izvestnyy, A., Johnson, S.R., Kadija, K., Kargin, N., Karpushkin, N., Kashirin, E., Kiełbowicz, M., Kireyeu, V.A., Kitagawa, H., Kolesnikov, R., Kolev, D., Korzenev, A., Koshio, Y., Kovalenko, V.N., Kowalski, S., Kozłowski, B., Krasnoperov, A., Kucewicz, W., Kuchowicz, M., Kuich, M., Kurepin, A., László, A., Lewicki, M., Lykasov, G., Lyubushkin, V.V., Maćkowiak-Pawłowska, M., Majka, Z., Makhnev, A., Maksiak, B., Malakhov, A.I., Marcinek, A., Marino, A.D., Marton, K., Mathes, H.-J., Matulewicz, T., Matveev, V., Melkumov, G.L., Merzlaya, A., Messerly, B., Mik, L., Morawiec, A., Morozov, S., Nagai, Y., Nakadaira, T., Naskręt, M., Nishimori, S., Ozvenchuk, V., Panova, O., Paolone, V., Petukhov, O., Pidhurskyi, I., Płaneta, R., Podlaski, P., Popov, B.A., Porfy, B., Posiadała-Zezula, M., Prado, R.R., Prokhorova, D.S., Pszczel, D., Puławski, S., Puzović, J., Ravonel, M., Renfordt, R., Röhrich, D., Rondio, E., Roth, M., Rozpłochowski, L., Rumberger, B.T., Rumyantsev, M., Ruprecht, M., Rustamov, A., Rybczynski, M., Rybicki, A., Sakashita, K., Schmidt, K., Seryakov, A.Yu., Seyboth, P., Shiraishi, Y., Shukla, A., Słodkowski, M., Staszel, P., Stefanek, G., Stepaniak, J., Strikhanov, M., Ströbele, H., Šuša, T., Szuba, M., Szukiewicz, R., Taranenko, A., Tefelska, A., Tefelski, D., Tereshchenko, V., Toia, A., Tsenov, R., Turko, L., Tveter, T.S., Ulrich, R., Unger, M., Urbaniak, M., Valiev, F.F., Veberič, D., Vechernin, V.V., Volkov, V., Wickremasinghe, A., Wójcik, K., Wyszyński, O., Zaitsev, A., Zimmerman, E.D., Zviagina, A., Zwaska, R., and HEP, INSPIRE

Subjects
NA61, [PHYS.HEXP] Physics [physics]/High Energy Physics - Experiment [hep-ex], hep-ex, GeV, High Energy Physics - Experiment, flux, neutrino, beam, multiplicity, Nuclear Physics - Experiment, hadron, production, numerical calculations, Nuclear Experiment, Monte Carlo, Particle Physics - Experiment
Abstract

This paper presents multiplicity measurements of KS0, Λ, and Λ¯ produced in 120 GeV/c proton-carbon interactions. The measurements were made using data collected at the NA61/SHINE experiment during two different periods. Decays of these neutral hadrons impact the measured π+, π-, p and p¯ multiplicities in the 120 GeV/c proton-carbon reaction, which are crucial inputs for long-baseline neutrino experiment predictions of neutrino beam flux. The double-differential multiplicities presented here will be used to more precisely measure charged-hadron multiplicities in this reaction, and to reweight neutral hadron production in neutrino beam Monte Carlo simulations. This paper presents multiplicity measurements of $K^0_{\textrm{S}}$, $\Lambda$, and $\bar{\Lambda}$ produced in 120 GeV/$c$ proton-carbon interactions. The measurements were made using data collected at the NA61/SHINE experiment during two different periods. Decays of these neutral hadrons impact the measured $\pi^+$, $\pi^-$, $p$ and $\bar{p}$ multiplicities in the 120 GeV/$c$ proton-carbon reaction, which are crucial inputs for long-baseline neutrino experiment predictions of neutrino beam flux. The double-differential multiplicities presented here will be used to more precisely measure charged-hadron multiplicities in this reaction, and to re-weight neutral hadron production in neutrino beam Monte Carlo simulations.

Published
2022

9. Spectra and mean multiplicities of $\pi ^{-}$ in central${}^{40}$Ar+${}^{45}$Sc collisions at 13A, 19A, 30A, 40A, 75A and 150$A\,\text{ Ge }\text{ V }\!/\!\textit{c}$ beam momenta measured by the NA61/SHINE spectrometer at the CERN SPS

Author

Acharya, A., Adhikary, H., Allison, K.K., Andronov, E.V., Antićić, T., Babkin, V., Baszczyk, M., Bhosale, S., Blondel, A., Bogomilov, M., Brandin, A., Bravar, A., Bryliński, W., Brzychczyk, J., Buryakov, M., Busygina, O., Bzdak, A., Cherif, H., Ćirković, M., Csanad, M., Cybowska, J., Czopowicz, T., Damyanova, A., Davis, N., Deliyergiyev, M., Deveaux, M., Dmitriev, A., Dominik, W., Dorosz, P., Dumarchez, J., Engel, R., Feofilov, G.A., Fields, L., Fodor, Z., Garibov, A., Gaździcki, M., Golosov, O., Golovatyuk, V., Golubeva, M., Grebieszkow, K., Guber, F., Haesler, A., Igolkin, S.N., Ilieva, S., Ivashkin, A., Johnson, S.R., Kadija, K., Kargin, N., Kashirin, E., Kiełbowicz, M., Kireyeu, V.A., Klochkov, V., Kolesnikov, V.I., Kolev, D., Korzenev, A., Kovalenko, V.N., Kowalski, S., Koziel, M., Kozłowski, B., Krasnoperov, A., Kucewicz, W., Kuich, M., Kurepin, A., Larsen, D., László, A., Lazareva, T.V., Lewicki, M., Łojek, K., Lyubushkin, V.V., Maćkowiak-Pawłowska, M., Majka, Z., Maksiak, B., Malakhov, A.I., Marcinek, A., Marino, A.D., Marton, K., Mathes, H.J., Matulewicz, T., Matveev, V., Melkumov, G.L., Merzlaya, A.O., Messerly, B., Mik, Ł., Morozov, S., Nagai, Y., Naskręt, M., Ozvenchuk, V., Paolone, V., Petukhov, O., Pidhurskyi, I., Płaneta, R., Podlaski, P., Popov, B.A., Porfy, B., Posiadała-Zezula, M., Prokhorova, D.S., Pszczel, D., Puławski, S., Puzović, J., Ravonel, M., Renfordt, R., Röhrich, D., Rondio, E., Roth, M., Rumberger, B.T., Rumyantsev, M., Rustamov, A., Rybczynski, M., Rybicki, A., Sadhu, S., Sadovsky, A., Schmidt, K., Selyuzhenkov, I., Seryakov, A.Yu., Seyboth, P., Słodkowski, M., Staszel, P., Stefanek, G., Stepaniak, J., Strikhanov, M., Ströbele, H., Šuša, T., Taranenko, A., Tefelska, A., Tefelski, D., Tereshchenko, V., Toia, A., Tsenov, R., Turko, L., Ulrich, R., Unger, M., Uzhva, D., Valiev, F.F., Veberič, D., Vechernin, V.V., Wickremasinghe, A., Wójcik, K., Wyszyński, O., Zaitsev, A., Zimmerman, E.D., Zwaska, R., Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE (UMR_7585)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), and NA61/SHINE

Subjects
NA61, CERN Lab, heavy ion: scattering, Nuclear Theory, scandium, mass spectrum: transverse, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], matter: hadronic, Nuclear Experiment, pi: multiplicity, hep-ex, mass: transverse, strong interaction, nucleus, nucleon, critical phenomena, CERN SPS, proton synchrotron, beam: momentum, argon, slope, spectrometer, pi: rapidity, Particle Physics - Experiment, pi: transverse momentum, experimental results
Abstract

The physics goal of the strong interaction program of the NA61/SHINE experiment at the CERN Super Proton Synchrotron (SPS) is to study the phase diagram of hadronic matter by a scan of particle production in collisions of nuclei with various sizes at a set of energies covering the SPS energy range. This paper presents differential inclusive spectra of transverse momentum, transverse mass and rapidity of $\pi^-$ mesons produced in \textit{central} ${}^{40}$Ar+${}^{45}$Sc collisions at beam momenta of 13A, 19A, 30A, 40A, 75A and 150A GeV/c. Energy and system size dependence of parameters of these distributions - mean transverse mass, the inverse slope parameter of transverse mass spectra, width of the rapidity distribution and mean multiplicity - are presented and discussed. Furthermore, the dependence of the ratio of the mean number of produced pions to the mean number of wounded nucleons on the collision energy was derived. The results are compared to predictions of several models. The physics goal of the strong interaction program of the NA61/SHINE experiment at the CERN Super Proton Synchrotron (SPS) is to study the phase diagram of hadronic matter by a scan of particle production in collisions of nuclei with various sizes at a set of energies covering the SPS energy range. This paper presents differential inclusive spectra of transverse momentum, transverse mass and rapidity of $\pi ^{-}$ mesons produced in central${}^{40}$Ar+${}^{45}$Sc collisions at beam momenta of 13A, 19A, 30A, 40A, 75A and 150$A\,\text{ Ge }\text{ V }\!/\!\textit{c}$. Energy and system size dependence of parameters of these distributions – mean transverse mass, the inverse slope parameter of transverse mass spectra, width of the rapidity distribution and mean multiplicity – are presented and discussed. Furthermore, the dependence of the ratio of the mean number of produced pions to the mean number of wounded nucleons on the collision energy was derived. The results are compared to predictions of several models. The physics goal of the strong interaction program of the NA61/SHINE experiment at the CERN Super Proton Synchrotron (SPS) is to study the phase diagram of hadronic matter by a scan of particle production in collisions of nuclei with various sizes at a set of energies covering the SPS energy range. This paper presents differential inclusive spectra of transverse momentum, transverse mass and rapidity of $\pi^{-}$ mesons produced in $central$ ${}^{40}$Ar+${}^{45}$Sc collisions at beam momenta of 13$A$, 19$A$, 30$A$, 40$A$, 75$A$ and 150$A$ GeV/$c$. Energy and system size dependence of parameters of these distributions -- mean transverse mass, the inverse slope parameter of transverse mass spectra, width of the rapidity distribution and mean multiplicity -- are presented and discussed. Furthermore, the dependence of the ratio of the mean number of produced pions to the mean number of wounded nucleons on the collision energy was derived. The results are compared to predictions of several models.

Published
2021

10. Measurements of Ξ (1530) and Ξ ¯ (1530) production in proton–proton interactions at √sNN = 17.3 GeV in the NA61/SHINE experiment

Author

Acharya, A., Adhikary, H., Allison, K.K., Amin, N., Andronov, E.V., Antićić, T., Babkin, V., Balkova, Y., Baszczyk, M., Bhosale, S., Blondel, A., Bogomilov, M., Brandin, A., Bravar, A., Bryliński, W., Brzychczyk, J., Buryakov, M., Busygina, O., Bzdak, A., Cherif, H., Ćirković, M., Csanad, M., Cybowska, J., Czopowicz, T., Damyanova, A., Davis, N., Deliyergiyev, M, Deveaux, M., Dmitriev, A., Dominik, W., Dorosz, P., Dumarchez, J., Engel, Ralph, Feofilov, G.A., Fields, L., Fodor, Z., Garibov, A., Gaździcki, M., Golosov, O., Golovatyuk, V., Golubeva, M., Grebieszkow, K., Guber, F., Haesler, A., Igolkin, S.N., Ilieva, S., Ivashkin, A., Johnson, S.R., Kadija, K., Kargin, N., Kashirin, E., Kiełbowicz, M., Kireyeu, V.A., Klochkov, V., Kolesnikov, V.I., Kolev, D., Korzenev, A., Kovalenko, V.N., Kowalski, S., Kozłowski, B., Krasnoperov, A., Kucewicz, W., Kuich, M., Kurepin, A., Larsen, D., László, A., Lazareva, T.V., Lewicki, M., Łojek, K., Lyubushkin, V.V., Maćkowiak-Pawłowska, M., Majka, Z., Maksiak, B., Malakhov, A.I., Marcinek, A., Marino, A.D., Marton, K., Mathes, H.-J., Matulewicz, T., Matveev, V., Melkumov, G.L., Merzlaya, A.O., Messerly, B., Mik, L., Morozov, S., Nagai, Y, Naskręt, M., Ozvenchuk, V., Paolone, V., Petukhov, O., Pidhurskyi, I., Płaneta, R., Podlaski, P., Popov, B.A., Porfy, B., Posiadała-Zezula, M., Prokhorova, D.S., Pszczel, D., Puławski, S., Puzović, J., Ravonel, M., Renfordt, R., Röhrich, Dieter, Rondio, E., Roth, M., Rumberger, B.T., Rumyantsev, M., Rustamov, A., Rybczynski, M., Rybicki, A., Sadhu, S., Sadovsky, A., Schmidt, K., Selyuzhenkov, I., Seryakov, A. Yu., Seyboth, P., Słodkowski, M., Staszel, P., Stefanek, G., Stepaniak, J., Strikhanov, M., Ströbele, H., Šuša, T., Taranenko, A., Tefelska, A., Tefelski, D., Tereshchenko, V., Toia, A., Tsenov, R., Turko, L., Ulrich, R., Unger, M., Urbaniak, M., Uzhva, D., Valiev, F.F., Veberič, D., Vechernin, V.V., Wickremasinghe, A., Wójcik, K., Wyszyński, O., Zaitsev, A., Zimmerman, E.D., and Zwaska, R.

Abstract

Double-differential yields of Ξ(1530)0Ξ(1530)0 and Ξ¯¯¯¯(1530)0Ξ¯(1530)0 resonances produced in p+p interactions were measured at a laboratory beam momentum of 158 GeV /c GeV /c. This measurement is the first of its kind in p+p interactions below LHC energies. It was performed at the CERN SPS by the NA61/SHINE collaboration. Double-differential distributions in rapidity and transverse momentum were obtained from a sample of 26×10626×106 inelastic events. The spectra are extrapolated to full phase space resulting in mean multiplicity of Ξ(1530)0Ξ(1530)0 (6.73±0.25±0.67)×10−46.73±0.25±0.67)×10−4 and Ξ¯¯¯¯(1530)0Ξ¯(1530)0 (2.71±0.18±0.18)×10−42.71±0.18±0.18)×10−4. The rapidity and transverse momentum spectra and mean multiplicities were compared to predictions of string-hadronic and statistical model calculations. publishedVersion

Published
2021

11. Measurements of π±, K±, p and p¯ spectra in 7Be+9Be collisions at beam momenta from 19A to 150A GeV/c with the NA61/SHINE spectrometer at the CERN SPS

Author

Acharya, A., Adhikary, H., Aduszkiewicz, A., Allison, K.K., Andronov, E.V., Antićić, T., Babkin, V., Baszczyk, M., Bhosale, S., Blondel, A., Bogomilov, M., Brandin, A., Bravar, A., Bryliński, W., Brzychczyk, J., Buryakov, M., Busygina, O., Bzdak, A., Cherif, H., Ćirković, M., Csanad, M., Cybowska, J., Czopowicz, T., Damyanova, A., Davis, N., Deliyergiyev, M., Deveaux, M., Dmitriev, A., Dominik, W., Dorosz, P., Dumarchez, J., Engel, Ralph, Feofilov, G.A., Fields, L., Fodor, Z., Garibov, A., Gaździcki, M., Golosov, O., Golovatyuk, V., Golubeva, M., Grebieszkow, K., Guber, F., Haesler, A., Igolkin, S.N., Ilieva, S., Ivashkin, A., Johnson, S.R., Kadija, K., Kargin, N., Kashirin, E., Kiełbowicz, M., Kireyeu, V.A., Klochkov, V., Kolesnikov, V.I., Kolev, D., Korzenev, A, Kovalenko, V.N., Kowalski, S., Koziel, M., Kozłowski, B., Krasnoperov, A., Kucewicz, W., Kuich, M., Kurepin, A., Larsen, Dag Toppe, László, A., Lazareva, T.V., Lewicki, M., Łojek, K., Lyubushkin, V.V., Maćkowiak-Pawłowska, M., Majka, Z., Maksiak, B., Malakhov, A.I., Marcinek, A., Marino, A.D., Marton, K., Mathes, H.-J., Matulewicz, T., Matveev, V., Melkumov, G.L., Merzlaya, A.O., Messerly, B., Mik, L., Morozov, S., Mrówczyński, S., Nagai, Y., Naskręt, M., Ozvenchuk, V., Paolone, V., Petukhov, O., Płaneta, R., Podlaski, P., Popov, B.A., Porfy, B., Posiadała-Zezula, M., Prokhorova, D.S., Pszczel, D., Puławski, S., Puzović, J., Ravonel, M., Renfordt, R., Röhrich, Dieter, Rondio, E., Roth, M., Rumberger, B.T., Rumyantsev, M., Rustamov, A., Rybczynski, M., Rybicki, A., Sadhu, S., Sadovsky, A., Schmidt, K., Selyuzhenkov, I., Seryakov, A. Yu., Seyboth, P., Słodkowski, M., Staszel, P., Stefanek, G., Stepaniak, J., Strikhanov, M., Ströbele, H., Šuša, T., Taranenko, A., Tefelska, A., Tefelski, D., Tereshchenko, V., Toia, Alberica, Tsenov, R., Turko, L., Ulrich, R., Unger, M., Uzhva, D., Valiev, F.F., Veberič, D., Vechernin, V.V., Wickremasinghe, A., Włodarczyk, Z., Wójcik, K., Wyszyński, O., Zimmerman, E.D., and Zwaska, R.

Subjects
Nuclear Experiment
Abstract

The NA61/SHINE experiment at the CERN Super Proton Synchrotron (SPS) studies the onset of deconf inement in hadron matter by a scan of particle production in collisions of nuclei with various sizes at a set of energies covering the SPS energy range. This paper presents results on inclusive double-differential spectra, transverse momentumandrapidity distributions and mean multiplicities of π±, K±, p and ¯p produced in the 20% most central 7Be+9Be collisions at beam momenta of 19A,30A,40A,75A and 150A GeV/c. The energy dependence of the K±/π± ratios as well as of inverse slope parameters of the K± transverse mass distributions are close to those found in inelastic p+p reactions. The new results are compared to the world data on p+p and Pb+Pb collisions as well as to predictions of the Epos, Urqmd, Ampt, Phsd and Smash models. publishedVersion

Published
2021

12. European League against Rheumatism (EULAR)/American College of Rheumatology (ACR) SLE classification criteria item performance

Author

Aringer, M. Brinks, R. Dörner, T. Daikh, D. Mosca, M. Ramsey-Goldman, R. Smolen, J.S. Wofsy, D. Boumpas, D.T. Kamen, D.L. Jayne, D. Cervera, R. Costedoat-Chalumeau, N. Diamond, B. Gladman, D.D. Hahn, B. Hiepe, F. Jacobsen, S. Khanna, D. Lerstrøm, K. Massarotti, E. McCune, J. Ruiz-Irastorza, G. Sanchez-Guerrero, J. Schneider, M. Urowitz, M. Bertsias, G. Hoyer, B.F. Leuchten, N. Schmajuk, G. Tani, C. Tedeschi, S.K. Touma, Z. Anic, B. Assan, F. Chan, T.M. Clarke, A.E. Crow, M.K. Czirják, L. Doria, A. Graninger, W. Halda-Kiss, B. Hasni, S. Izmirly, P.M. Jung, M. Kumánovics, G. Mariette, X. Padjen, I. Pego-Reigosa, J.M. Romero-Diaz, J. Rúa-Figueroa, I. Seror, R. Stummvoll, G.H. Tanaka, Y. Tektonidou, M.G. Vasconcelos, C. Vital, E.M. Wallace, D.J. Yavuz, S. Meroni, P.L. Fritzler, M.J. Naden, R. Costenbader, K. Johnson, S.R.

Subjects
musculoskeletal diseases, immune system diseases, skin and connective tissue diseases
Abstract

Background/objectives The European League Against Rheumatism (EULAR)/American College of Rheumatology (ACR) 2019 classification criteria for systemic lupus erythematosus system showed high specificity, while attaining also high sensitivity. We hereby analysed the performance of the individual criteria items and their contribution to the overall performance of the criteria. Methods We combined the EULAR/ACR derivation and validation cohorts for a total of 1197 systemic lupus erythematosus (SLE) and n=1074 non-SLE patients with a variety of conditions mimicking SLE, such as other autoimmune diseases, and calculated the sensitivity and specificity for antinuclear antibodies (ANA) and the 23 specific criteria items. We also tested performance omitting the EULAR/ACR criteria attribution rule, which defines that items are only counted if not more likely explained by a cause other than SLE. Results Positive ANA, the new entry criterion, was 99.5% sensitive, but only 19.4% specific, against a non-SLE population that included other inflammatory rheumatic, infectious, malignant and metabolic diseases. The specific criteria items were highly variable in sensitivity (from 0.42% for delirium and 1.84% for psychosis to 75.6% for antibodies to double-stranded DNA), but their specificity was uniformly high, with low C3 or C4 (83.0%) and leucopenia 80% for all items, explaining the higher overall specificity of the criteria set. © Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ.

Published
2021

13. Spectra and mean multiplicities of π− in central 40Ar+45Sc collisions at 13A, 19A, 30A, 40A, 75A and 150A GeV/c beam momenta measured by the NA61/SHINE spectrometer at the CERN SPS

Author

Acharya, A., Adhikary, H., Allison, K.K., Andronov, E.V., Antićić, T., Babkin, V., Baszczyk, M., Bhosale, S., Blondel, A., Bogomilov, M., Brandin, A., Bravar, A., Bryliński, W., Brzychczyk, J., Buryakov, M., Busygina, O., Bzdak, A., Cherif, H., Ćirković, M., Csanad, M., Cybowska, J., Czopowicz, T., Damyanova, A., Davis, N., Deliyergiyev, M, Deveaux, M., Dmitriev, A., Dominik, W., Dorosz, P., Dumarchez, J., Engel, Ralph, Feofilov, G.A., Fields, L., Fodor, Z., Garibov, A., Gaździcki, M., Golosov, O., Golovatyuk, V., Golubeva, M., Grebieszkow, K., Guber, F., Haesler, A., Igolkin, S.N., Ilieva, S., Ivashkin, A., Johnson, S.R., Kadija, K., Kargin, N., Kashirin, E., Kiełbowicz, M., Kireyeu, V.A., Klochkov, V., Kolesnikov, V, Kolev, D., Korzenev, A., Kovalenko, V.N., Kowalski, S., Koziel, M., Kozłowski, B., Krasnoperov, A., Kucewicz, W., Kuich, M., Kurepin, A., Larsen, D., László, A., Lazareva, T.V., Lewicki, M., Łojek, K., Lyubushkin, V.V., Maćkowiak-Pawłowska, M., Majka, Z., Maksiak, B., Malakhov, A.I., Marcinek, A., Marino, A.D., Marton, K., Mathes, H.-J., Matulewicz, T., Matveev, V., Melkumov, G.L., Merzlaya, A.O., Messerly, B., Mik, L., Morozov, S., Nagai, Y, Naskręt, M., Ozvenchuk, V., Paolone, V., Petukhov, O., Pidhurskyi, I., Płaneta, R., Podlaski, P., Popov, B.A., Porfy, B., Posiadała-Zezula, M., Prokhorova, D.S., Pszczel, D., Puławski, S., Puzović, J., Ravonel, M., Renfordt, R., Röhrich, Dieter, Rondio, E., Roth, M., Rumberger, B.T., Rumyantsev, M., Rustamov, A., Rybczynski, M., Rybicki, A., Sadhu, S., Sadovsky, A., Schmidt, K., Selyuzhenkov, I., Seryakov, A. Yu., Seyboth, P., Słodkowski, M., Staszel, P., Stefanek, G., Stepaniak, J., Strikhanov, M., Ströbele, H., Šuša, T., Taranenko, A., Tefelska, A., Tefelski, D., Tereshchenko, V., Toia, A., Tsenov, R., Turko, L., Ulrich, R., Unger, M., Uzhva, D., Valiev, F.F., Veberič, D., Vechernin, V.V., Wickremasinghe, A., Wójcik, K., Wyszyński, O., Zaitsev, A., Zimmerman, E.D., and Zwaska, R.

Subjects
Nuclear Theory, Nuclear Experiment
Abstract

The physics goal of the strong interaction program of the NA61/SHINE experiment at the CERN Super Proton Synchrotron (SPS) is to study the phase diagram of hadronic matter by a scan of particle production in collisions of nuclei with various sizes at a set of energies covering the SPS energy range. This paper presents differential inclusive spectra of transverse momentum, transverse mass and rapidity of π− mesons produced in central 40Ar+45Sc collisions at beam momenta of 13A, 19A, 30A, 40A, 75A and 150A Ge V /c. Energy and system size dependence of parameters of these distributions – mean transverse mass, the inverse slope parameter of transverse mass spectra, width of the rapidity distribution and mean multiplicity – are presented and discussed. Furthermore, the dependence of the ratio of the mean number of produced pions to the mean number of wounded nucleons on the collision energy was derived. The results are compared to predictions of several models. publishedVersion

Published
2021

14. Natural variability in the disease course of SSc-ILD: implications for treatment

Author

Vonk, M.C., Walker, U.A., Volkmann, E.R., Kreuter, M., Johnson, S.R., Allanore, Y., Vonk, M.C., Walker, U.A., Volkmann, E.R., Kreuter, M., Johnson, S.R., and Allanore, Y.

Abstract

Contains fulltext : 232636.pdf (Publisher’s version ) (Open Access), Interstitial lung disease (ILD) affects approximately 50% of patients with systemic sclerosis (SSc) and is the leading cause of death in SSc. Our objective was to gain insight into the progression of SSc-associated ILD (SSc-ILD). Using data from longitudinal clinical trials and observational studies, we assessed definitions and patterns of progression, risk factors for progression, and implications for treatment. SSc-ILD progression was commonly defined as exceeding specific thresholds of lung function worsening and/or increasing radiographic involvement. One definition used in several studies is decline in forced vital capacity (FVC) of ≥10%, or ≥5-10% plus a decline in diffusing capacity of the lung for carbon monoxide ≥15%. Based on these criteria, 20-30% of patients in observational cohorts develop progressive ILD, starting early in the disease course and progressing at a highly variable rate.Risk factors such as age, FVC, extent of fibrosis and presence of anti-topoisomerase I antibodies can help predict progression of SSc-ILD, though composite risk scores may offer greater predictive power. Whilst the variability of the disease course in SSc-ILD makes risk stratification of patients challenging, the decision to initiate, change or stop treatment should be based on a combination of the current disease state and the speed of progression.

Published
2021

15. Quantitative analysis of dopant distribution and activation across p-n junctions in AlGaAs/GaAs light-emitting diodes using off-axis electron holography

Author

Suk Chung, Johnson, S.R., Ding Ding, Yong-Hang Zhang, Smith, D.J., and McCartney, M.R.

Subjects
Aluminum alloys -- Electric properties, Aluminum alloys -- Optical properties, Electrostatic interactions -- Analysis, Gallium arsenide -- Electric properties, Gallium arsenide -- Optical properties, Holography -- Usage, Light-emitting diodes -- Electric properties, Light-emitting diodes -- Composition, Business, Electronics, Electronics and electrical industries
Abstract

A study was conducted to evaluate the electrostatic potential profile across the p-n junction of an AlGaAs/GaAs light-emitting diode (LED) with linearly graded triangular AlGaAs barriers using off-axis electron holography. Results suggest that electron holography measurements shared with modeling present device designers a helpful tool for analyzing doping profiles in complex heterostructures.

Published
2009

16. Protocol for a partially nested randomised controlled trial to evaluate the effectiveness of the scleroderma patient-centered intervention network COVID-19 home-isolation activities together (SPIN-CHAT) program to reduce anxiety among at-risk scleroderma patients

Author

Thombs, B.D., Kwakkenbos, L., Carrier, M.E., Bourgeault, A., Tao, L.D., Harb, S., Gagarine, M., Rice, D., Bustamante, L., Ellis, K., Duchek, D., Wu, Y., Bhandari, P.M., Neupane, D., Carboni-Jimenez, A., Henry, R.S., Krishnan, A., Sun, Y., Levis, B., He, C., Turner, K.A., Benedetti, A., Culos-Reed, N., El-Baalbaki, G., Hebblethwaite, S., Bartlett, S.J., Dyas, L., Patten, S., Varga, J., Fortune, C., Gietzen, A., Guillot, G., Lewis, N., Nielsen, K., Richard, M., Sauve, M., Welling, J., Baron, M., Furst, D.E., Gottesman, K., Malcarne, V., Mayes, M.D., Mouthon, L., Nielson, W.R., Riggs, R., Wigley, F., Assassi, S., Boutron, I., Ells, C., Ende, C. van den, Fligelstone, K., Frech, T., Godard, D., Harel, D., Hinchcliff, M., Hudson, M., Johnson, S.R., Larche, M., Leite, C., Nguyen, C., Pope, J., Portales, A., Rannou, F., Reyna, T.S.R., Schouffoer, A.A., Suarez-Almazor, M.E., Agard, C., Albert, A., Andre, M., Arsenault, G., Benzidia, I., Bernstein, E.J., Berthier, S., Bissonnette, L., Boire, G., Bruns, A., Carreira, P., Casadevall, M., Chaigne, B., Chung, L., Cohen, P., Correia, C., Dagenais, P., Denton, C., Domsic, R., Dubois, S., Dunne, J.V., Dunogue, B., Fare, R., Farge-Bancel, D., Fortin, P.R., Gill, A., Gordon, J., Granel-Rey, B., Gyger, G., Hachulla, E., Hatron, P.Y., Herrick, A.L., Hij, A., Hoa, S., Ikic, A., Jones, N., Fernandes, A.J.D., Kafaja, S., Khalidi, N., Lambert, M., Launay, D., Liang, P., Maillard, H., Maltez, N., Manning, J., Marie, I., Martin, M., Martin, T., Masetto, A., Maurier, F., Mekinian, A., Melchor, S., Nikpour, M., Olagne, L., Poindron, V., Proudman, S., Regent, A., Riviere, S., Robinson, D., Rodriguez, E., Roux, S., Smets, P., Smith, D., Sobanski, V., Spiera, R., Steen, V., Stevens, W., Sutton, E., Terrier, B., Thorne, C., Wilcox, P., Ayala, M.C., Ostbo, N., Scleroderma Patient-ctr Interventi, and SPIN Investigators

Subjects
Coronavirus, COVID-19, Systemic sclerosis, Mental health, Anxiety, RCT, Trial, Scleroderma
Abstract

Objective: Contagious disease outbreaks and related restrictions can lead to negative psychological outcomes, particularly in vulnerable populations at risk due to pre-existing medical conditions. No randomised controlled trials (RCTs) have tested interventions to reduce mental health consequences of contagious disease outbreaks. The primary objective of the Scleroderma Patient-centered Intervention Network COVID-19 Home-isolation Activities Together (SPIN-CHAT) Trial is to evaluate the effect of a videoconference-based program on symptoms of anxiety. Secondary objectives include evaluating effects on symptoms of depression, stress, loneliness, boredom, physical activity, and social interaction.Methods: The SPIN-CHAT Trial is a pragmatic RCT that will be conducted using the SPIN-COVID-19 Cohort, a sub-cohort of the SPIN Cohort. Eligible participants will be SPIN-COVID-19 Cohort participants without a positive COVID-19 test, with at least mild anxiety (PROMIS Anxiety 4a v1.0 T-score >= 55), not working from home, and not receiving current counselling or psychotherapy. We will randomly assign 162 participants to intervention groups of 7 to 10 participants each or waitlist control. We will use a partially nested RCT design to reflect dependence between individuals in training groups but not in the waitlist control. The SPIN-CHAT Program includes activity engagement, education on strategies to support mental health, and mutual participant support. Intervention participants will receive the 4-week (3 sessions per week) SPIN-CHAT Program via video-conference. The primary outcome is PROMIS Anxiety 4a score immediately post-intervention.Ethics and dissemination: The SPIN-CHAT Trial will test whether a brief videoconference-based intervention will improve mental health outcomes among at-risk individuals during contagious disease outbreak.

Published
2020

17. K∗(892) meson production in inelastic p+p interactions at 158 GeV/c beam momentum measured by NA61/SHINEat the CERN SPS

Author

Aduszkiewicz, A., Andronov, E.V., Antićić, T., Babkin, V., Baszczyk, M., Bhosale, S., Blondel, A., Bogomilov, M., Brandin, A., Bravar, A., Bryliński, W., Brzychczyk, J., Buryakov, M., Busygina, O., Bzdak, A., Cherif, H., Ćirković, M., Csanad, M., Cybowska, J., Czopowicz, T., Damyanova, A., Davis, N., Deliyergiyev, M., Deveaux, M., Dmitriev, A., Dominik, W., Dorosz, P., Dumarchez, J., Engel, R., Feofilov, G.A., Fields, L., Fodor, Z., Garibov, A., Gaździcki, M., Golosov, O., Golovatyuk, V., Golubeva, M., Grebieszkow, K., Guber, F., Haesler, A., Igolkin, S.N., Ilieva, S., Ivashkin, A., Johnson, S.R., Kadija, K., Kaptur, E., Kargin, N., Kashirin, E., Kiełbowicz, M., Kireyeu, V.A., Klochkov, V., Kolesnikov, V.I., Kolev, D., Korzenev, A., Kovalenko, V.N., Kowalski, S., Koziel, M., Krasnoperov, A., Kucewicz, W., Kuich, M., Kurepin, A., Larsen, D., László, A., Lazareva, T.V., Lewicki, M., Łojek, K., Łysakowski, B., Lyubushkin, V.V., Maćkowiak-Pawłowska, M., Majka, Z., Maksiak, B., Malakhov, A.I., Manić, D., Marcinek, A., Marino, A.D., Marton, K., Mathes, H.-J., Matulewicz, T., Matveev, Victor, Melkumov, G.L., Merzlaya, A.O., Messerly, B., Mik, L., Morozov, S., Mrówczyński, S., Nagai, Y., Naskręt, M., Ozvenchuk, V., Paolone, V., Petukhov, O., Płaneta, R., Podlaski, P., Popov, B.A., Porfy, B., Posiadała-Zezula, M., Prokhorova, D.S., Pszczel, D., Puławski, S., Puzović, J., Ravonel, M., Renfordt, R., Richter-Wąs, E., Røhrich, Dieter, Rondio, E., Roth, M., Rumberger, B.T., Rumyantsev, M., Rustamov, A., Rybczynski, M., Rybicki, A., Sadovsky, A., Schmidt, K., Selyuzhenkov, I., Seryakov, A. Yu., Seyboth, P., Słodkowski, M., Staszel, P., Stefanek, G., Stepaniak, J., Strikhanov, M., Ströbele, H., Šuša, T., Taranenko, A., Tefelska, A., Tefelski, D., Tereshchenko, V., Toia, A., Tsenov, R., Turko, Ludwik, Ulrich, R., Unger, M., Valiev, F.F., Veberič, D., Vechernin, V.V., Wickremasinghe, A., Włodarczyk, Z., Wyszyński, O., Zimmerman, E.D., and Zwaska, R.

Subjects
High Energy Physics::Experiment, Nuclear Experiment
Abstract

The measurement of K∗(892)0 resonance production via its K+π− decay mode in inelastic p+p collisions at beam momentum 158 Ge V /c (sNN−−−−√=17.3 Ge V ) is presented. The data were recorded by the NA61/SHINE hadron spectrometer at the CERN Super Proton Synchrotron. The template method was used to extract the K∗(892)0 signal and double-differential transverse momentum and rapidity spectra were obtained. The full phase-space mean multiplicity of K∗(892)0 mesons was found to be (78.44±0.38(stat)±6.0(sys))⋅10−3. The NA61/SHINEresults are compared with the EPOS1.99 and Hadron Resonance Gas models as well as with world data from p+p and nucleus–nucleus collisions. publishedVersion

Published
2020

18. Measurement of $\phi$ Meson Production in $p + p$ Interactions at 40, 80 and 158 GeV/$c$ with the NA61/SHINE Spectrometer at the CERN SPS

Author

Aduszkiewicz, A., Andronov, E.V., Antićić, T., Babkin, V., Baszczyk, M., Bhosale, S., Blondel, A., Bogomilov, M., Brandin, A., Bravar, A., Bryliński, W., Brzychczyk, J., Buryakov, M., Busygina, O., Bzdak, A., Cherif, H., Ćirković, M., Csanad, M., Cybowska, J., Czopowicz, T., Damyanova, A., Davis, N., Deliyergiyev, M., Deveaux, M., Dmitriev, A., Dominik, W., Dorosz, P., Dumarchez, J., Engel, R., Feofilov, G.A., Fields, L., Fodor, Z., Garibov, A., Gaździcki, M., Golosov, O., Golovatyuk, V., Golubeva, M., Grebieszkow, K., Guber, F., Haesler, A., Igolkin, S.N., Ilieva, S., Ivashkin, A., Johnson, S.R., Kadija, K., Kaptur, E., Kargin, N., Kashirin, E., Kiełbowicz, M., Kireyeu, V.A., Klochkov, V., Kolesnikov, V.I., Kolev, D., Korzenev, A., Kovalenko, V.N., Kowalik, K., Kowalski, S., Koziel, M., Krasnoperov, A., Kucewicz, W., Kuich, M., Kurepin, A., Larsen, D., László, A., Lazareva, T.V., Lewicki, M., Łojek, K., Łysakowski, B., Lyubushkin, V.V., Maćkowiak-Pawłowska, M., Majka, Z., Maksiak, B., Malakhov, A.I., Manić, D., Marchionni, A., Marcinek, A., Marino, A.D., Marton, K., Mathes, H.-J., Matulewicz, T., Matveev, V., Melkumov, G.L., Merzlaya, A.O., Messerly, B., Mik, L., Morozov, S., Mrówczyński, S., Nagai, Y., Naskręt, M., Ozvenchuk, V., Paolone, V., Pavin, M., Petukhov, O., Płaneta, R., Podlaski, P., Popov, B.A., Porfy, B., Posiadała-Zezula, M., Prokhorova, D.S., Pszczel, D., Puławski, S., Puzović, J., Ravonel, M., Renfordt, R., Richter-Wąs, E., Röhrich, D., Rondio, E., Roth, M., Rumberger, B.T., Rumyantsev, M., Rustamov, A., Rybczynski, M., Rybicki, A., Sadovsky, A., Schmidt, K., Selyuzhenkov, I., Seryakov, A.Yu., Seyboth, P., Słodkowski, M., Staszel, P., Stefanek, G., Stepaniak, J., Strikhanov, M., Ströbele, H., Šuša, T., Taranenko, A., Tefelska, A., Tefelski, D., Tereshchenko, V., Toia, A., Tsenov, R., Turko, L., Ulrich, R., Unger, M., Valiev, F.F., Veberič, D., Vechernin, V.V., Wickremasinghe, A., Włodarczyk, Z., Wojtaszek-Szwarc, A., Wyszyński, O., Zambelli, L., Zimmerman, E.D., Zwaska, R., Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE (UMR_7585)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), and NA61/SHINE

Subjects
NA61, Phi(1020): yield, momentum dependence, [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], nucl-ex, transverse momentum dependence, mass spectrum: (K+ K-), 158 GeV/c, rapidity dependence, transverse momentum: momentum spectrum, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], Phi(1020): hadroproduction, Nuclear Physics - Experiment, Nuclear Experiment, 40 GeV/c, 80 GeV/c, p p: inelastic scattering, yield: measured, hep-ex, p: beam, CERN SPS, beam: momentum, High Energy Physics::Experiment, spectrometer, +K%2B+K%22">Phi(1020) --> K+ K, p p: colliding beams, Particle Physics - Experiment, experimental results, Phi(1020): hadronic decay
Abstract

Results on $\phi $ meson production in inelastic $p + p$ collisions at CERN SPS energies are presented. They are derived from data collected by the NA61/SHINE fixed target experiment, by means of invariant mass spectra fits in the $\phi \rightarrow K^+ K^- $ decay channel. They include the first ever measured double differential spectra of $\phi $ mesons as a function of rapidity $y$ and transverse momentum $p_{\text {T}}$ for proton beam momenta of $80 \, \hbox {GeV}/c$ and $158 \, \hbox {GeV}/c$, as well as single differential spectra of $y$ or $p_{\text {T}}$ for beam momentum of $40 \, \hbox {GeV}/c$. The corresponding total $\phi $ yields per inelastic $p + p$ event are obtained. These results are compared with existing data on $\phi $ meson production in $p + p$ collisions. The comparison shows consistency but superior accuracy of the present measurements. The emission of $\phi $ mesons in $p + p$ reactions is confronted with that occurring in $\mathrm{Pb} + \mathrm{Pb}$ collisions, and the experimental results are compared with model predictions. It appears that none of the considered models can properly describe all the experimental observations. Results on $\phi$ meson production in inelastic p+p collisions at CERN SPS energies are presented. They are derived from data collected by the NA61/SHINE fixed target experiment, by means of invariant mass spectra fits in the $\phi \to K^+K^-$ decay channel. They include the first ever measured double differential spectra of $\phi$ mesons as a function of rapidity $y$ and transverse momentum $p_T$ for proton beam momenta of 80 GeV/c and 158 GeV/c, as well as single differential spectra of $y$ or $p_T$ for beam momentum of 40 GeV/c. The corresponding total $\phi$ yields per inelastic p+p event are obtained. These results are compared with existing data on $\phi$ meson production in p+p collisions. The comparison shows consistency but superior accuracy of the present measurements. The emission of $\phi$ mesons in p+p reactions is confronted with that occurring in Pb+Pb collisions, and the experimental results are compared with model predictions. It appears that none of the considered models can properly describe all the experimental observables.

Published
2020

19. Measurements of multiplicity fluctuations of identified hadrons in inelastic proton-proton interactions at the CERN Super Proton Synchrotron

Author

Acharya, A., Adhikary, H., Aduszkiewicz, A., Allison, K.K., Andronov, E.V., Antićić, T., Babkin, V., Baszczyk, M., Bhosale, S., Blondel, A., Bogomilov, M., Brandin, A., Bravar, A., Bryliński, W., Brzychczyk, J., Buryakov, M., Busygina, O., Bzdak, A., Cherif, H., Ćirković, M., Csanad, M., Cybowska, J., Czopowicz, T., Damyanova, A., Davis, N., Deliyergiyev, M., Deveaux, M., Dmitriev, A., Dominik, W., Dorosz, P., Dumarchez, J., Engel, R., Feofilov, G.A., Fields, L., Fodor, Z., Garibov, A., Gaździcki, M., Golosov, O., Golovatyuk, V., Golubeva, M., Grebieszkow, K., Guber, F., Haesler, A., Igolkin, S.N., Ilieva, S., Ivashkin, A., Johnson, S.R., Kadija, K., Kargin, N., Kashirin, E., Kiełbowicz, M., Kireyeu, V.A., Klochkov, V., Kolesnikov, V.I., Kolev, D., Korzenev, A., Kovalenko, V.N., Kowalski, S., Koziel, M., Krasnoperov, A., Kucewicz, W., Kuich, M., Kurepin, A., Larsen, D., László, A., Lazareva, T.V., Lewicki, M., Łojek, K., Lyubushkin, V.V., Maćkowiak-Pawłowska, M., Majka, Z., Maksiak, B., Malakhov, A.I., Marcinek, A., Marino, A.D., Marton, K., Mathes, H.-J., Matulewicz, T., Matveev, V., Melkumov, G.L., Merzlaya, A.O., Messerly, B., Mik, L., Morozov, S., Mrówczyński, S., Nagai, Y., Naskręt, M., Ozvenchuk, V., Paolone, V., Petukhov, O., Pidhurskyi, I., Płaneta, R., Podlaski, P., Popov, B.A., Porfy, B., Posiadała-Zezula, M., Prokhorova, D.S., Pszczel, D., Puławski, S., Puzović, J., Ravonel, M., Renfordt, R., Röhrich, D., Rondio, E., Roth, M., Rumberger, B.T., Rumyantsev, M., Rustamov, A., Rybczynski, M., Rybicki, A., Sadhu, S., Sadovsky, A., Schmidt, K., Selyuzhenkov, I., Seryakov, A.Yu., Seyboth, P., Słodkowski, M., Staszel, P., Stefanek, G., Stepaniak, J., Strikhanov, M., Ströbele, H., Šuša, T., Taranenko, A., Tefelska, A., Tefelski, D., Tereshchenko, V., Toia, A., Tsenov, R., Turko, L., Ulrich, R., Unger, M., Uzhva, D., Valiev, F.F., Veberič, D., Vechernin, V.V., Wickremasinghe, A., Włodarczyk, Z., Wojcik, K., Wyszyński, O., Zaitsev, A., Zimmerman, E.D., Zwaska, R., Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE (UMR_7585)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), and NA61/SHINE

Subjects
NA61, FOS: Physical sciences, interaction [p p], QC770-798, [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], Astrophysics, momentum [beam], nucl-ex, High Energy Physics - Experiment, High Energy Physics - Experiment (hep-ex), Nuclear and particle physics. Atomic energy. Radioactivity, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], ddc:530, Nuclear Physics - Experiment, Nuclear Experiment (nucl-ex), scattering [nucleus nucleus], numerical calculations, Nuclear Experiment, Monte Carlo, p p: interaction, multiplicity: fluctuation, hep-ex, nucleus nucleus: scattering, QB460-466, beam: momentum, fluctuation [multiplicity], particle identification, CERN SPS Coll, Particle Physics - Experiment, experimental results
Abstract

Measurements of multiplicity fluctuations of identified hadrons produced in inelastic p+p interactions at 31, 40, 80, and 158~\GeVc beam momentum are presented. Three different measures of multiplicity fluctuations are used: the scaled variance $\omega$ and strongly intensive measures $\Sigma$ and $\Delta$. These fluctuation measures involve second and first moments of joint multiplicity distributions. Data analysis is performed using the Identity method which corrects for incomplete particle identification. Strongly intensive quantities are calculated in order to allow for a direct comparison to corresponding results on nucleus-nucleus collisions. The results for different hadron types are shown as a function of collision energy. A comparison with predictions of string-resonance Monte-Carlo models: Epos, Smash and Venus, is also presented., Comment: 32 pages, 14 figures

Published
2020
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20. Measurement of $\phi $ meson production in $p + p$ interactions at 40, 80 and $158 \, \hbox {GeV}/c$ with the NA61/SHINE spectrometer at the CERN SPS

Author

Aduszkiewicz, A., Andronov, E.V., Antićić, T., Babkin, V., Baszczyk, M., Bhosale, S., Blondel, A., Bogomilov, M., Brandin, A., Bravar, A., Bryliński, W., Brzychczyk, J., Buryakov, M., Busygina, O., Bzdak, A., Cherif, H., Ćirković, M., Csanad, M., Cybowska, J., Czopowicz, T., Damyanova, A., Davis, N., Deliyergiyev, M., Deveaux, M., Dmitriev, A., Dominik, W., Dorosz, P., Dumarchez, J., Engel, R., Feofilov, G.A., Fields, L., Fodor, Z., Garibov, A., Gaździcki, M., Golosov, O., Golovatyuk, V., Golubeva, M., Grebieszkow, K., Guber, F., Haesler, A., Igolkin, S.N., Ilieva, S., Ivashkin, A., Johnson, S.R., Kadija, K., Kaptur, E., Kargin, N., Kashirin, E., Kiełbowicz, M., Kireyeu, V.A., Klochkov, V., Kolesnikov, V.I., Kolev, D., Korzenev, A., Kovalenko, V.N., Kowalik, K., Kowalski, S., Koziel, M., Krasnoperov, A., Kucewicz, W., Kuich, M., Kurepin, A., Larsen, D., László, A., Lazareva, T.V., Lewicki, M., Łojek, K., Łysakowski, B., Lyubushkin, V.V., Maćkowiak-Pawłowska, M., Majka, Z., Maksiak, B., Malakhov, A.I., Manić, D., Marchionni, A., Marcinek, A., Marino, A.D., Marton, K., Mathes, H.J., Matulewicz, T., Matveev, V., Melkumov, G.L., Merzlaya, A.O., Messerly, B., Mik, Ł., Morozov, S., Mrówczyński, S., Nagai, Y., Naskręt, M., Ozvenchuk, V., Paolone, V., Pavin, M., Petukhov, O., Płaneta, R., Podlaski, P., Popov, B.A., Porfy, B., Posiadała-Zezula, M., Prokhorova, D.S., Pszczel, D., Puławski, S., Puzović, J., Ravonel, M., Renfordt, R., Richter-Wąs, E., Röhrich, D., Rondio, E., Roth, M., Rumberger, B.T., Rumyantsev, M., Rustamov, A., Rybczynski, M., Rybicki, A., Sadovsky, A., Schmidt, K., Selyuzhenkov, I., Seryakov, A.Yu., Seyboth, P., Słodkowski, M., Staszel, P., Stefanek, G., Stepaniak, J., Strikhanov, M., Ströbele, H., Šuša, T., Taranenko, A., Tefelska, A., Tefelski, D., Tereshchenko, V., Toia, A., Tsenov, R., Turko, L., Ulrich, R., Unger, M., Valiev, F.F., Veberič, D., Vechernin, V.V., Wickremasinghe, A., Włodarczyk, Z., Wojtaszek-Szwarc, A., Wyszyński, O., Zambelli, L., Zimmerman, E.D., Zwaska, R., Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE (UMR_7585)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), and NA61/SHINE

Subjects
NA61, Phi(1020): yield, momentum dependence, p: beam, CERN SPS, [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], transverse momentum dependence, mass spectrum: (K+ K-), 158 GeV/c, rapidity dependence, transverse momentum: momentum spectrum, beam: momentum, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], Phi(1020): hadroproduction, High Energy Physics::Experiment, spectrometer, Nuclear Experiment, 80 GeV/c, 40 GeV/c, +K%2B+K%22">Phi(1020) --> K+ K, p p: colliding beams, yield: measured, p p: inelastic scattering, experimental results, Phi(1020): hadronic decay
Abstract

International audience; Results on $\phi $ meson production in inelastic $p + p$ collisions at CERN SPS energies are presented. They are derived from data collected by the NA61/SHINE fixed target experiment, by means of invariant mass spectra fits in the $\phi \rightarrow K^+ K^- $ decay channel. They include the first ever measured double differential spectra of $\phi $ mesons as a function of rapidity $y$ and transverse momentum $p_{\text {T}}$ for proton beam momenta of $80 \, \hbox {GeV}/c$ and $158 \, \hbox {GeV}/c$, as well as single differential spectra of $y$ or $p_{\text {T}}$ for beam momentum of $40 \, \hbox {GeV}/c$. The corresponding total $\phi $ yields per inelastic $p + p$ event are obtained. These results are compared with existing data on $\phi $ meson production in $p + p$ collisions. The comparison shows consistency but superior accuracy of the present measurements. The emission of $\phi $ mesons in $p + p$ reactions is confronted with that occurring in $\mathrm{Pb} + \mathrm{Pb}$ collisions, and the experimental results are compared with model predictions. It appears that none of the considered models can properly describe all the experimental observations.

Published
2020
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21. Performance of the 2019 EULAR/ACR classification criteria for systemic lupus erythematosus in early disease, across sexes and ethnicities

Author

Johnson, S.R. Brinks, R. Costenbader, K.H. Daikh, D. Mosca, M. Ramsey-Goldman, R. Smolen, J.S. Wofsy, D. Boumpas, D.T. Kamen, D.L. Jayne, D. Cervera, R. Costedoat-Chalumeau, N. Diamond, B. Gladman, D.D. Hahn, B. Hiepe, F. Jacobsen, Sø. Khanna, D. Lerstrøm, K. Massarotti, E. McCune, J. Ruiz-Irastorza, G. Sanchez-Guerrero, J. Schneider, M. Urowitz, M. Bertsias, G. Hoyer, B.F. Leuchten, N. Tani, C. Tedeschi, S.K. Touma, Z. Schmajuk, G. Anic, B. Assan, F. Chan, T.M. Clarke, A.E. Crow, M.K. Czirják, L. Doria, A. Graninger, W.B. Halda-Kiss, B. Hasni, S. Izmirly, P.M. Jung, M. Kumánovics, G. Mariette, X. Padjen, I. Pego-Reigosa, J.M. Romero-Diaz, J. Rúa-Figueroa, Í. Seror, R. Stummvoll, G.H. Tanaka, Y. Tektonidou, M.G. Vasconcelos, C. Vital, E.M. Wallace, D.J. Yavuz, S. Meroni, P.L. Fritzler, M.J. Naden, R. Dörner, T. Aringer, M.

Subjects
musculoskeletal diseases, immune system diseases, skin and connective tissue diseases
Abstract

Objectives The European League Against Rheumatism (EULAR)/American College of Rheumatology (ACR) 2019 Classification Criteria for systemic lupus erythematosus (SLE) have been validated with high sensitivity and specificity. We evaluated the performance of the new criteria with regard to disease duration, sex and race/ethnicity, and compared its performance against the Systemic Lupus International Collaborating Clinics (SLICC) 2012 and ACR 1982/1997 criteria. Methods Twenty-one SLE centres from 16 countries submitted SLE cases and mimicking controls to form the validation cohort. The sensitivity and specificity of the EULAR/ACR 2019, SLICC 2012 and ACR 1982/1997 criteria were evaluated. Results The cohort consisted of female (n=1098), male (n=172), Asian (n=118), black (n=68), Hispanic (n=124) and white (n=941) patients; with an SLE duration of 1 to

Published
2020

24. Microscopic electroabsorption line shape analysis for Ga(AsSb)/GaAs heterostructures

Author

Buckers, C., Blume, G., Thranhardt, A., Schlichenmaier, C., Klar, P.J., Weiser, G., Koch, S.W., Hader, J., Moloney, J.V., Sweeney, S.J., Hosea, T.J.C, J.-B. Wang, Johnson, S.R., and Y.-H. Zhang

Subjects
Gallium compounds -- Electric properties, Gallium compounds -- Chemical properties, Arsenic compounds -- Electric properties, Arsenic compounds -- Chemical properties, Antimony -- Electric properties, Antimony -- Chemical properties, Physics
Abstract

Electric-field modulated absorption (EA) and reflectance spectroscopy are used to analyze a series of Ga(AsSb)/GaAs/(AlGa)As samples with varying GaAs spacer width. The analysis has shown that the band alignment between GaAs and Ga(AsSb) is of type II with a conduction band offset of approximately 40 meV.

Published
2007

25. The Scleroderma Patient-Centered Intervention Network Self-Management Program: Protocol for a randomized feasibility trial

Author

Carrier, M.E., Kwakkenbos, L., Nielson, W.R., Fedoruk, C., Nielsen, K., Milette, K., Pope, J., Frech, T., Gholizadeh, S., Hummers, L., Johnson, S.R., Piotrowski, P., Jewett, L.R., Gordon, J.K., Chung, L., Bilsker, D., Turner, K.A., Cumin, J., Welling, J.J.K.C., Fortune, C., Leite, C., Gottesman, K., Sauvé, M., Rodríguez-Reyna, T.S., Hudson, M., Larché, M., Breda, W. van, Suarez-Almazor, M.E., Bartlett, S.J., Malcarne, V.L., Mayes, M.D., Boutron, I., Mouthon, L., Wigley, F.M., Thombs, B.D., Carrier, M.E., Kwakkenbos, L., Nielson, W.R., Fedoruk, C., Nielsen, K., Milette, K., Pope, J., Frech, T., Gholizadeh, S., Hummers, L., Johnson, S.R., Piotrowski, P., Jewett, L.R., Gordon, J.K., Chung, L., Bilsker, D., Turner, K.A., Cumin, J., Welling, J.J.K.C., Fortune, C., Leite, C., Gottesman, K., Sauvé, M., Rodríguez-Reyna, T.S., Hudson, M., Larché, M., Breda, W. van, Suarez-Almazor, M.E., Bartlett, S.J., Malcarne, V.L., Mayes, M.D., Boutron, I., Mouthon, L., Wigley, F.M., and Thombs, B.D.

Abstract

Contains fulltext : 219726.pdf (publisher's version ) (Open Access), Background: Systemic sclerosis (SSc), or scleroderma, is a rare disease that often results in significant disruptions to activities of daily living and can negatively affect physical and psychological well-being. Because there is no known cure, SSc treatment focuses on reducing symptoms and disability and improving health-related quality of life (HRQoL). Self-management programs are known to increase self-efficacy for disease management in many chronic diseases. The Scleroderma Patient-centered Intervention Network (SPIN) developed a Web-based self-management program (SPIN self-management; SPIN-SELF) to increase self-efficacy for disease management and to improve HRQoL for patients with SSc. Objective: The proposed study aims to assess the feasibility of conducting a full-scale randomized controlled trial (RCT) of the SPIN-SELF program by evaluating the trial implementation processes, required resources and management, scientific aspects, and participant acceptability and usage of the SPIN-SELF program. Methods: The SPIN-SELF feasibility trial will be conducted via the SPIN Cohort. The SPIN Cohort was developed as a framework for embedded pragmatic trials using the cohort multiple RCT design. In total, 40 English-speaking SPIN Cohort participants with low disease management self-efficacy (Self-Efficacy for Managing Chronic Disease Scale score ≤7), who have indicated interest in using a Web-based self-management program, will be randomized with a 3:2 ratio into the SPIN-SELF program or usual care for 3 months. Feasibility outcomes include trial implementation processes, required resources and management, scientific aspects, and patient acceptability and usage of the SPIN-SELF program. Results: Enrollment of the 40 participants occurred between July 5, 2019, and July 27, 2019. By November 25, 2019, data collection of trial outcomes was completed. Data analysis is underway, and results are expected to be published in 2020. Conclusions: The SPIN-SELF program is a self-h

Published
2020

27. NA61/SHINE Collaboration

Author

Acharya, A., primary, Adhikary, H., additional, Aduszkiewicz, A., additional, Andronov, E.V., additional, Antićić, T., additional, Babkin, V., additional, Baszczyk, M., additional, Bhosale, S., additional, Blondel, A., additional, Bogomilov, M., additional, Brandin, A., additional, Bravar, A., additional, Bryliński, W., additional, Brzychczyk, J., additional, Buryakov, M., additional, Busygina, O., additional, Bzdak, A., additional, Cherif, H., additional, Ćirković, M., additional, Csanad, M., additional, Cybowska, J., additional, Czopowicz, T., additional, Damyanova, A., additional, Davis, N., additional, Deliyergiyev, M., additional, Deveaux, M., additional, Dmitriev, A., additional, Dominik, W., additional, Dorosz, P., additional, Dumarchez, J., additional, Engel, R., additional, Feofilov, G.A., additional, Fields, L., additional, Fodor, Z., additional, Garibov, A., additional, Gaździcki, M., additional, Golosov, O., additional, Golovatyuk, V., additional, Golubeva, M., additional, Grebieszkow, K., additional, Guber, F., additional, Haesler, A., additional, Igolkin, S.N., additional, Ilieva, S., additional, Ivashkin, A., additional, Johnson, S.R., additional, Kadija, K., additional, Kargin, N., additional, Kashirin, E., additional, Kiełbowicz, M., additional, Kireyeu, V.A., additional, Klochkov, V., additional, Kolesnikov, V.I., additional, Kolev, D., additional, Korzenev, A., additional, Kovalenko, V.N., additional, Kowalski, S., additional, Koziel, M., additional, Krasnoperov, A., additional, Kucewicz, W., additional, Kuich, M., additional, Kurepin, A., additional, Larsen, D., additional, László, A., additional, Lazareva, T.V., additional, Lewicki, M., additional, Łojek, K., additional, Lyubushkin, V.V., additional, Maćkowiak-Pawłowska, M., additional, Majka, Z., additional, Maksiak, B., additional, Malakhov, A.I., additional, Marcinek, A., additional, Marino, A.D., additional, Marton, K., additional, Mathes, H.-J., additional, Matulewicz, T., additional, Matveev, V., additional, Melkumov, G.L., additional, Merzlaya, A.O., additional, Messerly, B., additional, Mik, Ł., additional, Morozov, S., additional, Mrówczyński, S., additional, Nagai, Y., additional, Naskręt, M., additional, Ozvenchuk, V., additional, Paolone, V., additional, Petukhov, O., additional, Płaneta, R., additional, Podlaski, P., additional, Popov, B.A., additional, Porfy, B., additional, Posiadała-Zezula, M., additional, Prokhorova, D.S., additional, Pszczel, D., additional, Puławski, S., additional, Puzović, J., additional, Ravonel, M., additional, Renfordt, R., additional, Röhrich, D., additional, Rondio, E., additional, Roth, M., additional, Rumberger, B.T., additional, Rumyantsev, M., additional, Rustamov, A., additional, Rybczynski, M., additional, Rybicki, A., additional, Sadhu, S., additional, Sadovsky, A., additional, Schmidt, K., additional, Selyuzhenkov, I., additional, Seryakov, A.Yu., additional, Seyboth, P., additional, Słodkowski, M., additional, Staszel, P., additional, Stefanek, G., additional, Stepaniak, J., additional, Strikhanov, M., additional, Ströbele, H., additional, Šuša, T., additional, Taranenko, A., additional, Tefelska, A., additional, Tefelski, D., additional, Tereshchenko, V., additional, Toia, A., additional, Tsenov, R., additional, Turko, L., additional, Ulrich, R., additional, Unger, M., additional, Uzhva, D., additional, Valiev, F.F., additional, Veberič, D., additional, Vechernin, V.V., additional, Wickremasinghe, A., additional, Włodarczyk, Z., additional, Wojcik, K., additional, Wyszyński, O., additional, Zimmerman, E.D., additional, and Zwaska, R., additional

Published
2021
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36. 2019 European League Against Rheumatism/American College of Rheumatology Classification Criteria for Systemic Lupus Erythematosus

Author

Aringer, M. Costenbader, K. Daikh, D. Brinks, R. Mosca, M. Ramsey-Goldman, R. Smolen, J.S. Wofsy, D. Boumpas, D.T. Kamen, D.L. Jayne, D. Cervera, R. Costedoat-Chalumeau, N. Diamond, B. Gladman, D.D. Hahn, B. Hiepe, F. Jacobsen, Sø. Khanna, D. Lerstrøm, K. Massarotti, E. McCune, J. Ruiz-Irastorza, G. Sanchez-Guerrero, J. Schneider, M. Urowitz, M. Bertsias, G. Hoyer, B.F. Leuchten, N. Tani, C. Tedeschi, S.K. Touma, Z. Schmajuk, G. Anic, B. Assan, F. Chan, T.M. Clarke, A.E. Crow, M.K. Czirják, L. Doria, A. Graninger, W. Halda-Kiss, B. Hasni, S. Izmirly, P.M. Jung, M. Kumánovics, G. Mariette, X. Padjen, I. Pego-Reigosa, J.M. Romero-Diaz, J. Rúa-Figueroa Fernández, Í. Seror, R. Stummvoll, G.H. Tanaka, Y. Tektonidou, M.G. Vasconcelos, C. Vital, E.M. Wallace, D.J. Yavuz, S. Meroni, P.L. Fritzler, M.J. Naden, R. Dörner, T. Johnson, S.R.

Subjects
immune system diseases, skin and connective tissue diseases
Abstract

Objective To develop new classification criteria for systemic lupus erythematosus (SLE) jointly supported by the European League Against Rheumatism (EULAR) and the American College of Rheumatology (ACR). Methods This international initiative had four phases. (1) Evaluation of antinuclear antibody (ANA) as an entry criterion through systematic review and meta-regression of the literature and criteria generation through an international Delphi exercise, an early patient cohort and a patient survey. (2) Criteria reduction by Delphi and nominal group technique exercises. (3) Criteria definition and weighting based on criterion performance and on results of a multi-criteria decision analysis. (4) Refinement of weights and threshold scores in a new derivation cohort of 1001 subjects and validation compared with previous criteria in a new validation cohort of 1270 subjects. Results The 2019 EULAR/ACR classification criteria for SLE include positive ANA at least once as obligatory entry criterion; followed by additive weighted criteria grouped in seven clinical (constitutional, haematological, neuropsychiatric, mucocutaneous, serosal, musculoskeletal, renal) and three immunological (antiphospholipid antibodies, complement proteins, SLE-specific antibodies) domains, and weighted from 2 to 10. Patients accumulating ≥10 points are classified. In the validation cohort, the new criteria had a sensitivity of 96.1% and specificity of 93.4%, compared with 82.8% sensitivity and 93.4% specificity of the ACR 1997 and 96.7% sensitivity and 83.7% specificity of the Systemic Lupus International Collaborating Clinics 2012 criteria. Conclusion These new classification criteria were developed using rigorous methodology with multidisciplinary and international input, and have excellent sensitivity and specificity. Use of ANA entry criterion, hierarchically clustered and weighted criteria reflect current thinking about SLE and provide an improved foundation for SLE research. © Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ.

Published
2019

37. Shortening patient-reported outcome measures through optimal test assembly: Application to the Social Appearance Anxiety Scale in the Scleroderma Patient-centered Intervention Network Cohort

Author

Harel, D., Mills, S.D., Kwakkenbos, L., Carrier, M.E., Nielsen, K., Portales, A., Bartlett, S.J., Malcarne, V.L., Thombs, B.D., Baron, M., Furst, D.E., Gottesman, K., Mayes, M.D., Mouthon, L., Nielson, W.R., Riggs, R., Sauve, M., Wigley, F., Assassi, S., Boutron, I., Maia, A.C., El-Baalbaki, G., Ells, C., Ende, C. van den, Fligelstone, K., Fortune, C., Frech, T., Godard, D., Hudson, M., Impens, A., Jang, Y., Johnson, S.R., Kennedy, A.T., Korner, A., Larche, M., Leite, C., Marra, C., Pope, J., Reyna, T.S.R., Schouffoer, A.A., Steele, R.J., Suarez-Almazor, M.E., Welling, J., Wong-Rieger, D., Agard, C., Albert, A., Andre, M., Arsenault, G., Benmostefa, N., Benzidia, I., Berthier, S., Bissonnette, L., Boire, G., Bruns, A., Carreira, P., Casadevall, M., Chaigne, B., Chung, L., Cohen, P., Dagenais, P., Denton, C., Domsic, R., Dubois, S., Dunne, J.V., Dunogue, B., Esquinca, A., Fare, R., Farge-Bancel, D., Fortin, P.R., Gill, A., Gordon, J., Granel-Rey, B., Grange, C., Gyger, G., Hachulla, E., Hatron, P.Y., Herrick, A.L., Hij, A., Hinchcliff, M., Ikic, A., Jones, N., Fernandes, A.J.D., Kafaja, S., Khalidi, N., Korman, B., Launay, D., Liang, P., London, J., Luna, D., Maillard, H., Manning, J., Martin, M., Martin, T., Masetto, A., Maurier, F., Mekinian, A., Melchor, S., Nikpour, M., Paule, R., Proudman, S., Regent, A., Riviere, S., Robinson, D., Rodriguez, E., Roux, S., Smets, P., Smith, D., Sobanski, V., Spiera, R., Steen, V., Stevens, W., Sutton, E., Terrier, B., Thorne, C., Varga, J., Wilcox, P., Wilson, M., Cumin, J., Fox, R.S., Gholizadeh, S., Jewett, L.R., Levis, B., Pepin, M.R., Turner, K.A., Lambert, M., and SPIN Investigators

Subjects
Adult, Male, medicine.medical_specialty, systemic sclerosis, Concurrent validity, Anxiety, Fear of negative evaluation, Cohort Studies, Experimental Psychopathology and Treatment, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Rheumatology, Cronbach's alpha, medicine, Humans, Patient Reported Outcome Measures, optimal test assembly, 030212 general & internal medicine, Aged, Aged, 80 and over, Scleroderma, Systemic, business.industry, Research, short form, Social anxiety, Reproducibility of Results, generalized partial credit model, General Medicine, Middle Aged, stomatognathic diseases, Cross-Sectional Studies, Convergent validity, patient reported outcome measure, Physical Appearance, Body, Physical therapy, Female, Patient-reported outcome, medicine.symptom, business, 030217 neurology & neurosurgery, Cohort study
Abstract

ObjectivesThe Social Appearance Anxiety Scale (SAAS) is a 16-item measure that assesses social anxiety in situations where appearance is evaluated. The objective was to use optimal test assembly (OTA) methods to develop and validate a short-form SAAS based on objective and reproducible criteria.DesignThis study was a cross-sectional analysis of baseline data from adults enrolled in the Scleroderma Patient-centered Intervention Network (SPIN) Cohort.SettingAdults in the SPIN Cohort in the present study were enrolled at 28 centres in Canada, the USA and the UK.ParticipantsThe SAAS was administered to 926 adults with scleroderma.Primary and secondary measuresThe SAAS, Brief Fear of Negative Evaluation II (BFNE II), Brief Satisfaction with Appearance Scale (Brief-SWAP), Patient Health Questionnaire-8 (PHQ8) and Social Interaction Anxiety Scale-6 (SIAS-6) were collected, as well as demographic characteristics.ResultsOTA methods identified a maximally informative shortened version for each possible form length between 1 and 15 items. The final shortened version was selected based on prespecified criteria for reliability, concurrent validity and statistically equivalent convergent validity with the BFNE II scale. A five-item short version was selected (SAAS-5). The SAAS-5 had a Cronbach’s α of 0.95 and had high concurrent validity with the full-length form (r=0.97). The correlation of the SAAS-5 with the BFNE II was 0.66, which was statistically equivalent to that of the full-length form. Furthermore, the correlation of the SAAS-5 with the two subscales of the Brief-SWAP, and the SIAS-6, were statistically equivalent to that of the full-length form.ConclusionsOTA was an efficient method for shortening the full-length SAAS to create the SAAS-5.

Published
2019

38. Measurements of production and inelastic cross sections for p+C , p+Be , and p+Al at 60 GeV/c and p+C and p+Be at 120 GeV/c

Author

Aduszkiewicz, A., Andronov, E.V., Antićić, T., Babkin, V., Baszczyk, M., Bhosale, S., Blondel, A., Bogomilov, M., Brandin, A., Bravar, A., Bryliński, W., Brzychczyk, J., Buryakov, M., Busygina, O., Bzdak, A., Cherif, H., Ćirković, M., Csanad, M., Cybowska, J., Czopowicz, T., Damyanova, A., Davis, N., Deliyergiyev, M., Deveaux, M., Dmitriev, A., Dominik, W., Dorosz, P., Dumarchez, J., Engel, R., Feofilov, G.A., Fields, L., Fodor, Z., Garibov, A., Gaździcki, M., Golosov, O., Golubeva, M., Grebieszkow, K., Guber, F., Haesler, A., Igolkin, S.N., Ilieva, S., Ivashkin, A., Johnson, S.R., Kadija, K., Kaptur, E., Kargin, N., Kashirin, E., Kiełbowicz, M., Kireyeu, V.A., Klochkov, V., Kolesnikov, V.I., Kolev, D., Korzenev, A., Kovalenko, V.N., Kowalik, K., Kowalski, S., Koziel, M., Krasnoperov, A., Kucewicz, W., Kuich, M., Kurepin, A., Larsen, D., László, A., Lazareva, T.V., Lewicki, M., Łojek, K., Łysakowski, B., Lyubushkin, V.V., Maćkowiak-Pawłowska, M., Majka, Z., Maksiak, B., Malakhov, A.I., Marchionni, A., Marcinek, A., Marino, A.D., Marton, K., Mathes, H.-J., Matulewicz, T., Matveev, V., Melkumov, G.L., Merzlaya, A.O., Messerly, B., Mik, Ł., Mills, G.B., Morozov, S., Mrówczyński, S., Nagai, Y., Naskręt, M., Ozvenchuk, V., Paolone, V., Pavin, M., Petukhov, O., Płaneta, R., Podlaski, P., Popov, B.A., Porfy, B., Posiadała-Zezula, M., Prokhorova, D.S., Pszczel, D., Puławski, S., Puzović, J., Ravonel, M., Renfordt, R., Richter-Wąs, E., Röhrich, D., Rondio, E., Roth, M., Rumberger, B.T., Rumyantsev, M., Rustamov, A., Rybczynski, M., Rybicki, A., Sadovsky, A., Schmidt, K., Selyuzhenkov, I., Seryakov, A.Yu., Seyboth, P., Słodkowski, M., Snoch, A., Staszel, P., Stefanek, G., Stepaniak, J., Strikhanov, M., Ströbele, H., Šuša, T., Taranenko, A., Tefelska, A., Tefelski, D., Tereshchenko, V., Toia, A., Tsenov, R., Turko, L., Ulrich, R., Unger, M., Valiev, F.F., Veberič, D., Vechernin, V.V., Wickremasinghe, A., Włodarczyk, Z., Wojtaszek-Szwarc, A., Wójcik, K., Wyszyński, O., Zambelli, L., Zimmerman, E.D., Zwaska, R., Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE (UMR_7585)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), and NA61/SHINE

Subjects
60 GeV/c, NA61, p nucleus: inelastic scattering, Astrophysics::High Energy Astrophysical Phenomena, carbon, p nucleus: interaction, CERN SPS, [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], beryllium, neutrino: flux, aluminum, 120 GeV/c, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], Physics::Accelerator Physics, Particle Physics Experiments, High Energy Physics::Experiment, spectrometer, Nuclear Experiment, channel cross section: measured, experimental results
Abstract

International audience; This paper presents measurements of production cross sections and inelastic cross sections for the following reactions: 60 GeV/c protons with C, Be, Al targets and 120 GeV/c protons with C and Be targets. The analysis is performed using the NA61/SHINE spectrometer at the CERN Super Proton Synchrotron. First measurements are obtained using protons at 120 GeV/c, while the results for protons at 60 GeV/c are compared with previously published measurements. These interaction cross section measurements are critical inputs for neutrino flux prediction in current and future accelerator-based long-baseline neutrino experiments.

Published
2019

39. Use of consensus methodology to determine candidate items for systemic lupus erythematosus classification criteria

Author

Johnson, S.R. Khanna, D. Daikh, D. Cervera, R. Costedoat-Chalumeau, N. Gladman, D.D. Hahn, B.H. Hiepe, F. Sánchez-Guerrero, J. Massarotti, E. Boumpas, D.T. Costenbader, K.H. Jayne, D. Dörner, T. Kamen, D.L. Mosca, M. Ramsey-Goldman, R. Smolen, J.S. Wofsy, D. Aringer, M.

Subjects
immune system diseases, skin and connective tissue diseases
Abstract

Objective. Given the complexity and heterogeneity of systemic lupus erythematosus (SLE), high-performing classification criteria are critical to advancing research and clinical care. A collaborative effort by the European League Against Rheumatism and the American College of Rheumatology was undertaken to generate candidate criteria, and then to reduce them to a smaller set. The objective of the current study was to select a set of criteria that maximizes the likelihood of accurate classification of SLE, particularly early disease. Methods. An independent panel of international SLE experts and the SLE classification criteria steering committee (conducting SLE research in Canada, Mexico, United States, Austria, Germany, Greece, France, Italy, and Spain) ranked 43 candidate criteria. A consensus meeting using nominal group technique (NGT) was conducted to reduce the list of criteria for consideration. Results. The expert panel NGT exercise reduced the candidate criteria for SLE classification from 43 to 21. The panel distinguished potential "entry criteria," which would be required for classification, from potential "additive criteria." Potential entry criteria were antinuclear antibody (ANA) = 1:80 (HEp-2 immunofluorescence), and low C3 and/or low C4. The use of low complement as an entry criterion was considered potentially useful in cases with negative ANA. Potential additive criteria included lupus nephritis by renal biopsy, autoantibodies, cytopenias, acute and chronic cutaneous lupus, alopecia, arthritis, serositis, oral mucosal lesions, central nervous system manifestations, and fever. Conclusion. The NGT exercise resulted in 21 candidate SLE classification criteria. The next phases of SLE classification criteria development will require refinement of criteria definitions, evaluation of the ability to cluster criteria into domains, and evaluation of weighting of criteria. Copyright © 2019. All rights reserved.

Published
2019

42. Contribution of single InGaAs quantum wells to the guided mode dispersion of InGaAs GaAs AlGaAs waveguides: model and experimental results

Author

Pacradouni, V., Morin, R., Kanskar, M., Young, Jeff F., Johnson, S.R., and Tiedje, T.

Subjects
Quantum wells -- Research, Waveguides -- Research, Gallium arsenide semiconductors -- Optical properties, Physics
Abstract

The group index dispersion of TE and TM polarized modes in single quantum well InGaAs AlGaAs GaAs graded index separate confinement heterostructure waveguides was obtained by high resolution Fabry-Perot fringe spacing measurements. The TE mode data, over a 175 nm range below the quantum well band gap, were compared with model computations of guided mode dispersion utilizing current empirical equations for the index dispersion of Al(sub x)Ga(sub 1-x) and GaAs, and various phenomenological equations for the TE index dispersion of the InGaAs quantum well. A satisfactory fit was observed when the quantum well was modeled as a two-dimensional set of equal strength oscillators with a constant density of states, plus a single 1S excitonic level.

Published
1996

44. A muti-objective approach to integrating agricultural economic and environmental policies

Author

Lakshiminarayan, P.G., Johnson, S.R., and Bouzaher, A.

Subjects
Agricultural pollution -- Economic aspects, Environmental policy -- Analysis, Decision-making -- Models, Soil erosion -- Environmental aspects, Agricultural chemicals -- Environmental aspects, Environmental issues
Abstract

A multi-objective decision-making model of agricultural nonpoint source (NPS) pollution reveals the trade-offs between goals and the utility of incorporating environmental objectives. The model is empirically tested out in an eastern Iowa watershed, drained by two major river systems. There is a substantial trade-off between economic and environmental goals, and even between environmental goals.

Published
1995

45. Temperature dependence of the Urbach edge in GaAs

Author

Johnson, S.R. and Tiedje, T.

Subjects
Gallium arsenide semiconductors -- Optical properties, Absorption spectra -- Measurement, Semiconductor wafers -- Research, Physics
Published
1995

47. How nutrition policy affects food and agricultural policy

Author

Johnson, S.R.

Subjects
Nutrition policy -- Analysis, Agricultural policy -- Analysis, Food/cooking/nutrition
Abstract

The impact of the improved understanding of nutrition and the importance of the diet in nutrition status has had subtle but far-reaching consequences for food and agricultural policy. Many of the changes in the food supply are in response to increased consciousness of diet, nutrition and health status. The simple connection between nutrition policy and food and agricultural policy follows from the sovereignty of the consumer. Nutrition policy influences consumers' attitudes and choices. These impact the behavior of agents in the food and production system. And, if properly designed, food and agricultural policies can accelerate the process of adapting the production and distribution systems for agriculture and food to better meet the demands of the more informed consumer. Policies that reflect the behavior of consumers and supply better information to the agents in the food and agricultural system will be the most effective. J. Nutr. 124: 1871S-1877S, 1994. INDEXING KEY WORDS: * nutrition policy * agricultural policy * food policy

Published
1994

48. Production efficiency and agricultural reform in Ukraine

Author

Johnson, S.R., Bouzaher, Aziz, Carriquiry, Alicia, Jensen, Helen, and Lakshminarayan, P.G.

Subjects
Agricultural productivity -- Analysis, Agricultural industry, Economics
Abstract

A study was conducted on agricultural production efficiency and reform in Ukraine. Ukrainian crop productivity has lagged below the levels of most developed countries despite having one of the most productive land resources in the Former Soviet Union and Europe. Stochastic frontier analysis shows that Ukrainian farm technical efficiency is declining and may be affected by agricultural reform.

Published
1994

49. Lymphangioleiomyomatosis: a case-control study of perinatal and early life events

Author

Whale, C.I., Johnson, S.R., Phillips, K.G., Newton, S.A., Lewis, S.A., and Tattersfield, A.E.

Subjects
Women -- Health aspects -- Physiological aspects, Lung diseases, Interstitial -- Evaluation -- Genetic aspects, Uterine fibroids -- Physiological aspects -- Genetic aspects, Statistics -- Physiological aspects -- Health aspects, Tuberous sclerosis -- Genetic aspects, Health, Evaluation, Physiological aspects, Genetic aspects, Health aspects
Abstract

Thorax 2003;58:979-982 Background: Lymphangioleiomyomatosis (LAM), a rare disease affecting women, is caused by somatic mutations in the tuberous sclerosis complex genes. Methods: A case-control questionnaire study was carried out examining [...]

Published
2003

50. Emerging agricultural institutions in the New Independent States

Author

Johnson, S.R.

Subjects
Institutional economics -- International aspects, Economic development -- International aspects, Agricultural societies -- Management, Agricultural industry, Economics, Commonwealth of Independent States -- Economic aspects
Abstract

The development of new agricultural institutions in the New Independent States (NIS) of the former Soviet Union (FSU) has resulted in enhanced attention to the philosophy of institutional economics. It was suggested that since institutional economics emphasize collective action of institutions, it could play an important role in the economic transformation of the FSU. Among the economic reform measures proposed for the NIS were price liberalization and the development of institutions to support free market systems.

Published
1993

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