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Lung cancer is one of the most common malignant tumors with growing morbidity and mortality worldwide. Several treatments are used to manage lung cancer, including surgery, radiotherapy and chemotherapy, as well as molecular-targeted therapy. However, the current measures are still far from satisfactory. Therefore, the current research should focus on exploring the molecular mechanism and then finding an effective treatment. Interestingly, we and others have embarked on a line of investigations focused on the mechanism of lung cancer. Specifically, lncRNA small nucleolar RNA host gene has been shown to be associated with biological characteristics and therapeutic resistance of lung cancer. In addition, small nucleolar RNA host genes may be used as diagnostic biomarker in the future. Herein, we will provide a brief review demonstrating the importance of small nucleolar RNA host genes in lung cancer, especially non-small cell lung cancer. Although lncRNA has shown a crucial role in tumor-related research, a large number of studies are needed to validate its clinical application in the future.

Incorporation of nanoparticles into polymer blend to obtain finely dispersed morphology has been considered as an effective strategy to prepare nanocomposites. Owing to the renewable and degradable characters, cellulose nanocrystals (CNCs) have been proposed to tailor the phase morphology of poly (L-lactic acid) blend for producing high-performance fused deposition modeling (FDM) consumables. However, the main challenge associated with the ternary systems is the dispersion of the highly hydrophilic CNCs in nonpolar PLLA blend by industrial melt blending without involving solution. Herein, with polyvinyl acetate (PVAc) modified CNCs powder (a mixture of PVAc grafted from CNCs and PVAc homopolymer latex), the selective dispersion of CNCs in PLLA has been achieved by simple melt processing of PLLA/TPU (polyether polyurethane)/CNCs blend. This results in the ultra-fine TPU droplets at nanoscale in PLLA and improves the melt processibility of composites in FDM due to the decreased viscosity ratio of the dispersed/matrix and the enhanced melt elasticity of PLLA. Combined with the intensive shear and continuous stretch effect during FDM, aligned TPU nanofibers (TNFs) were in-situ formed along the elongational flow direction during deposition, which in turn contributed to the improvement of PLLA/TPU/CNCs with 5 wt% filler loading in tensile ductility by 418%, inter-layer adhesion strength and notched impact toughness by 261% and 210%, respectively, as well as achieved good dimensional accuracy and very fine surface quality.

This paper focused on the stable operation and control strategy of the hydro-turbine governing system (HTGS) in an isolated-grid operation mode. The stable operation of a hydropower station in isolated-grid operation mode is important for the safe operation of a power system. A regional power grid can be isolated from a main grid due to factors such as natural disasters, grid failures, and human errors. The Lunzua hydropower station in Zambia is often forced to operate as an isolated grid. To ensure its safe and stable operation, we conducted isolated-grid regulation tests in conjunction with field testing of HTGS and determined the parameters of the HTGS for stable operation of the isolated grid. In the field test, we first set the no-load and initial parameters for the isolated-grid mode through the no-load disturbance tests. Through simulated isolated-grid operation tests, we verified and further tuned the initial parameters. Meanwhile, we propose a control strategy for the transition between large-grid and isolated-grid modes. Through operational tests, we determined the parameters for stable operation in isolated-grid mode. During testing, we found that the water flow inertia time constant Tw was too large and the inertial time constant Ta of the impulsive generator was too small, which resulted in a narrow stability range of proportional–integral–derivative (PID) controller parameters for isolated-grid operation. The governing stability for isolated-grid operation was thus sensitive to the PID parameters. Since the isolated-grid field operation test of the HTGS of the Lunzua hydropower station was completed in August 2016, the generator units have maintained safe and stable operation in large-grid and isolated-grid modes, which validated the isolated-grid operation parameters and control strategy for the transition between large-grid and isolated-grid modes as determined by our test method. The methods of field test and control strategies used for isolated-grid operation have important practical value for the isolated grid operation of hydropower stations.

To verify the superiority ofA total of 150 patients with CSA were randomly divided into a Tongtuo Fu's acupuncture group, a Tongtuo acupuncture group and a conventional Fu's acupuncture group, 50 cases in each group. Under the guidance of the theory ofAfter treatment, the scores of cervical vertigo symptoms and function evaluation scale and PSV in each group were higher than those before treatment (

To investigate the characteristics of platelet antibody in patients with hematological diseases, so as to research the effect of immunized platelet transfusion refractoriness (PTR) on the prognosis of allogeneic hematopoietic stem cell transplantation (allo-HSCT) recepients with malignant hematological diseases patients.The clinical data of platelet antibody positive patients tested by Capture-P in the First Affiliated Hospital of Soochow University from July 1, 2014 to July 1, 2019 were retrospectively analyzed, including sex, age, disease, platelet transfusion assessments, CD34In 5 years, 913 (7.28%) hematologic patients with platelet antibody positive were identified, the detection rate of females (513 cases) were higher than males (400 cases). Among the 913 patients, the antibody positive rates of 520 patients with malignant hematological diseases (acute myeloid leukemia, acute lymphoblastic leukemia and myelodysplastic syndrome) showed significantly statistical different (10.27%, 8.01%, and 7.20%) (P0.01), and the positive rate of the acute myeloid leukemia of those patients was higher than myelodysplastic syndrome patients(α0.0125). There were 35 cases diagnosed as immunized PTR before allo-HSCT, the platelet increments, 14 h correct count increment, progression-free survival rate and overall survival rate of those patients were significantly lower than those in negative transfusion effective patients (P0.01), while the percentage of ABO matching was significantly higher (α0.0125).The positive rate of platelet antibody identification is high in females and acute myeloid leukemia patients, and immunized PTR caused by antibody is a risk factor for poor prognosis of allo-HSCT in malignant hematological disease patients.免疫性血小板输注无效对恶性血液病异基因造血干细胞移植患者的影响.探讨血小板抗体在血液病患者中产生的特点，研究免疫性血小板输注无效对恶性血液病异基因造血干细胞移植（allo-HSCT）患者临床预后的影响.回顾性分析2014年7月1日－2019年7月1日苏州大学附属第一医院利用Capture-P方法鉴定血小板抗体阳性患者的性别、年龄、疾病、血小板输注、CD345年内，共有913例血小板抗体鉴定阳性血液病患者（7.28%），女性（513例）多于男性（400例），其中520例恶性血液病（急性髓细胞白血病、急性淋巴细胞白血病和骨髓增生异常综合征）患者抗体阳性率（10.27%、8.01%和7.20%）明显不同（P0.01），急性髓系白血病患者的抗体阳性率高于骨髓增生异常综合征的（α0.0125）。移植前共有35例免疫性血小板输注无效患者，其血小板增加数、14 h校正血小板增高指数、无进展生存率和总生存率明显低于阴性输注有效组（P0.01），而ABO全相合比例明显高于阴性输注有效组（α0.0125）.女性和急性髓系白血病患者血小板抗体鉴定阳性率高，由抗体引起的免疫性血小板输注无效是引起恶性血液病患者allo-HSCT预后不良的风险因素.

One-dimensional nanoribbons usually exhibit considerably different properties compared to their monolayer counterparts due to the formation of edge states and limited width. In this study, we systematically investigate the stability, electronic structures and magnetic properties of CrSiTe3 single-layer nanoribbons with different edge configurations and ribbon widths using first-principles calculations. The results show that the edge energies (less than 0.4 eV/A) for all studied CrSiTe3 nanoribbons are much lower than that of graphene and many transition-metal dichalcogenide nanoribbons, indicating their stability and easy formation. Compared to the CrSiTe3 monolayer with ferromagnetic semiconductor characteristics, some of CrSiTe3 nanoribbons (N-SiCr-ZNRs, N-Te-ZNRs, N-TeCr-ANRs and N-Te-ANRs) become half-metal due to the hybridization between the d orbitals of edge Cr atoms and the p orbitals of edge Te atoms. While N-SiTe-ANRs are bipolar magnetic semiconductors, in which the states near Fermi level are localized around the nanoribbons edge. Our results show that CrSiTe3 single-layer nanoribbons are promising candidates suitable for applications in spintronic devices.

Four different welding sequences of double-pulse MIG welding were conducted for 6061-T6 aluminum alloy automobile bumpers by using nonlinear elastoplasticity finite element method based on ABAQUS software. The post-welding residual stress and deformation were definitely different among the four welding sequences. The results showed that the highest temperature in Solution A was approximately 200 °C higher than the melting point of base metal. High residual stress was resulted from this large temperature gradient and mainly concentrated on the welding vicinity between beam and crash box. The welding deformation primarily occurred in both of the contraction of two-ends of the beam and the self-contraction of crash box. Compared with other welding sequences, the residual stress in Solution A was the smallest, whereas the welding deformation was the largest. However, the optimal sequence was Solution B because of the effective reduction of residual stress and good assembly requirements.

To observe the short-term and long-term clinical effect on posterior circulation ischemic vertigo treated with "Ninety patients with posterior circulation ischemic vertigo were randomly divided into a treatment group and a control group, 45 cases in each group. The patients of the two groups were all treated on the base of neurological medicine. In the control group, Flunarizine Hydrochloride was prescribed for oral administration (5 mg, once daily, for 21 days totally). In the treatment group, acupuncture of "After treatment, the total effective rate of the treatment group was 91.11% (41/45) and 75.56% (34/45) in the control group. The total effective rate in the treatment group was higher than that in the control group ("

To solve the defects of bottom concave appearing in the extrusion experiments of complex hollow aluminium profiles, a 3D finite element model for simulating steady-state porthole die extrusion process was established based on HyperXtrude software using Arbitrary Lagrangian–Eulerian (ALE) algorithm. The velocity distribution on the cross-section of the extrudate at the die exit and pressure distribution at different heights in the welding chamber were quantitatively analyzed. To obtain an uniformity of metal flow velocity at the die exit, the porthole die structure was optimized by adding baffle plates. After optimization, maximum displacement in the Y direction at the bottom of profile decreases from 1.1 to 0.15 mm, and the concave defects are remarkably improved. The research method provides an effective guidance for improving extrusion defects and optimizing the metal flow of complex hollow aluminium profiles during porthole die extrusion.

A combination of thermal fracturing and stress-induced fracturing, i.e. coupled thermal-mechanical fracturing, occurs under the effect of combustion-generated heat and stress in underground coal gasification. Controlling the cracking of roofs and floors and the precise positioning of the combustion zone in underground coal gasification requires full knowledge of the characteristics of the coupled thermal-mechanical fracturing of the surrounding rocks. This study considers the variation in the physical and mechanical parameters of the rock with temperature and rock heterogeneity in order to derive a mathematical model of coupled thermal-mechanical fracturing. Then, a numerical simulation is performed, from which the following conclusions can be reached. First, temperature increases expand fractures, which emerge in the highest temperature area, before extending to lower temperature areas. Second, fracture density is directly related to temperature, with higher temperature corresponding to greater fracture density. Third, the cracking rate increases linearly with time in stages. For m = 1, the growth rate of the cracking rate are 55.76%/h, 26.08%/h correspondingly during the first stage (from 0.8 h to 1.6 h) and the second stage (from 1.6 h to 2 h).While for m = 2, the growth rates are 18.50%/h, 40.99%/h correspondingly during the first stage (from 0.8 h to 1.3 h) and the second stage (from 1.3 h to 2 h). Finally, fracture formation speed is slower in more homogeneous conditions when other conditions are unchanged. A few fractures emerge in the sample after 1.3 h for m = 2; the sample cracking rate is only 14.84%, which is far lower than for m = 1 at the same time (32.31%). Similarly, the cracking rate reaches 29.94% after 1.6 h for m = 2 (still far lower than that for m = 1 at the same time, which is 46.91%). The average growth rate of cracking rate for m = 1 (27.16%/h) is quicker than that of m = 2(21.77%/h).

With the integration of new large-scale energy sources into grids, power system stability is facing huge challenges. The primary frequency regulation of hydropower generators is an important regulation method for grid frequency stability and power balance. It can effectively suppress the grid frequency fluctuations caused by the high proportion of new energy sources, and it plays a very important role in maintaining the stability of the power system. The regulation parameters of the primary frequency regulation of a hydropower unit have a significant impact on its regulation capabilities and performance indices. The experimental analysis of the effects of the regulation parameters is crucial for the safe and stable operation of a hydropower unit. A frequency regulation parameter test on a hydropower station was conducted in this study to determine the effects of the regulation parameters on the performance of the primary frequency regulation. This provides a reference for the selection of the regulation parameters of a hydropower unit.

Digital cartridge governor, as a new direction of hydraulic turbine governor control, has been applied in engineering practice, but its relative theory and engineering application research are few. The engineering application of novel hydraulic turbine governing system based on digital cartridge valve technology is taken as the research object in this paper. Combining theory with engineering application, control strategies and rules of the digital cartridge turbine governor in key concerns of engineering applications such as closed-loop power regulation, isolated grid operation, the low-frequency de-excitation and the over-speed of load rejection of bulb turbine units are discussed, and engineering applications of digital cartridge turbine governor are summarized, which can be used for reference to solve some problems in the application of governor.

How to determine the network structure is an open problem in extreme learning machine (ELM). Error minimized extreme learning machine (EM-ELM) is a simple and efficient approach to determine the number of hidden nodes. However, similar to other constructive ELM, EM-ELM lays much emphasis on the convergence accuracy, which may obtain a single-hidden-layer feedforward neural networks (SLFN) with good convergence performance but bad condition. In this paper, an effective approach based on error minimized ELM and particle swarm optimization (PSO) is proposed to adaptively determine the structure of SLFN for regression problem. In the new method, to establish a compact and well-conditioning SLFN, the hidden node optimized by PSO is added to the SLFN one by one. Moreover, not only the regression accuracy but also the condition value of the hidden output matrix of the network is considered in the optimization process. Experiment results on various regression problems verify that the proposed algorithm achieves better generalization performance with fewer hidden nodes than other constructive ELM.

Clear cell renal cell carcinoma (ccRCC) is one of the most common types of kidney cancer and is accompanied by a poor prognosis due to a high potential for metastasis and recurrence. The mechanism of ccRCC metastasis is not well known. N-lysine methyltransferase KMT5A serves a crucial role in the progression of human cancer; however, the function of KMT5A in the development of ccRCCs has not yet been investigated, which has triggered an interest in investigating the potential association between KMT5A and ccRCC. The present study demonstrates for the first time that KMT5A is a driving factor in ccRCC metastasis. The KMT5A expression level was revealed to be significantly higher in ccRCC tissues compared with adjacent normal tissues. Patients with ccRCC whose tumors expressed high levels of KMT5A were demonstrated to have significantly shorter postoperative survival times. In vitro knockdown of KMT5A expression in 786-O cells inhibited cell migration and invasion. KMT5A reduced cadherin-1 (CDH1) protein levels by directly inhibiting its transcription. The CDH1 mRNA levels were inversely correlated with KMT5A expression in ccRCC samples. Patients with high tumor KMT5A or low CDH1 levels had the poorest prognosis with the shortest overall survival (OS) time, and this combination was demonstrated to be an independent prognostic indicator for patient OS time in ccRCC, more accurate than monitoring KMT5A or CDH1 alone. Together, these results indicate that KMT5A serves a vital role in ccRCC development and progression, and it may be a novel target for ccRCC treatment and prevention.

Medical gas is a large class of bioactive gases used in clinical medicine and basic scientific research. At present, the role of medical gas in neuroprotection has received growing attention. Stroke is a leading cause of death and disability in adults worldwide, but current treatment is still very limited. The common pathological changes of these two types of stroke may include excitotoxicity, free radical release, inflammation, cell death, mitochondrial disorder, and blood-brain barrier disruption. In this review, we will discuss the pathological mechanisms of stroke and the role of two medical gases (hydrogen and hydrogen sulfide) in stroke, which may potentially provide a new insight into the treatment of stroke.

The existence of huge volumes of near-duplicate videos shows a rising demand on effective near-duplicate video retrieval technique in copyright violation and search result re-ranking. In this paper, Kernel Partial Least Squares (KPLS) is used to find strong information correlation in near-duplicate videos. Furthermore, to solve the problem of “curse of kernelization” when querying a large-scale video database, we propose a Toeplitz Kernel Partial Least Squares method. The Toeplitz matrix multiplication can be implemented by the Fast Fourier Transform (FFT) to accelerate the computation. Extensive experiments on the widely used CC_WEB_VIDEO dataset demonstrate that the proposed approach exhibits superior performance of near-duplicate video retrieval (NDVR) over state-of-the-art methods, such as BCS, SE, SSBelt and CCA, achieving a mean average precision (MAP) score of 0.9665.

In this paper, physical layer security is investigated in the dual-hop amplify-and-forward cognitive relay network with one secondary source, one secondary destination, multiple cognitive relays under the presence of multiple primary receivers and eavesdroppers which can be either primary receivers or secondary receivers. The power allocation method at secondary source and artificial noise at relays are utilized to secure the secondary source-destination transmission. Two optimization problems, namely, to maximize the received signal-to-interference-and-noise ratio of secondary source in the lightly-loaded relay cluster situation, and to minimize the relay cluster total power in the fully-loaded relay cluster situation, are formulated. In addition, these two problems should ensure both physical-layer security and lower interference temperature. The semi-definite relaxation technique is used to solve the considered optimization problems. In the second problems, we further optimize the performance with the help of the bisection method. Complexity analysis shows that our proposed method is efficient and also can be solved in polynomial time. Theoretical analysis and the Monte-Carlo simulation results validate the proposed method. Copyright © 2016 John Wiley & Sons, Ltd.

Early preoperative diagnosis of central lymph node metastasis (CNM) is crucial to improve survival rates among patients with papillary thyroid carcinoma (PTC). Here, we analyzed clinical data from 2862 PTC patients and developed a scoring system using multivariable logistic regression and testified by the validation group. The predictive diagnostic effectiveness of the scoring system was evaluated based on consistency, discrimination ability, and accuracy. The scoring system considered seven variables: gender, age, tumor size, microcalcification, resistance index >0.7, multiple nodular lesions, and extrathyroid extension. The area under the receiver operating characteristic curve (AUC) was 0.742, indicating a good discrimination. Using 5 points as a diagnostic threshold, the validation results for validation group had an AUC of 0.758, indicating good discrimination and consistency in the scoring system. The sensitivity of this predictive model for preoperative diagnosis of CNM was 4 times higher than a direct ultrasound diagnosis. These data indicate that the CNM prediction model would improve preoperative diagnostic sensitivity for CNM in patients with papillary thyroid carcinoma.

The seven-amino acid truncated (7ND) protein is an N-terminal deletion mutant of monocyte chemoattractant protein-1 (MCP-1) and it functions as a dominant-negative inhibitor. 7ND and wild-type MCP-1 form a heterodimer, which binds to MCP-1 receptors and inhibits monocyte chemotaxis. In the present study, the 7ND protein was cloned, expressed and purified. An MTT assay revealed that the proliferation of oral squamous cell carcinoma (OSCC) SCC25 cells was not affected following 3 days of treatment with synthetic 7ND protein. Serial dilutions of the 7ND protein were tested for monocyte migration and osteoclast differentiation, and tartrate-resistant acid phosphatase staining demonstrated that significantly fewer osteoclasts were differentiated from cluster of differentiation 14+ (CD14+) monocytes using magnetic activated cell sorting. Immunofluorescence confirmed these results and significantly less F-actin staining was observed in 7ND-treated osteoclasts. Furthermore, bone invasion was examined by subcutaneously injecting SCC25 cells into the area overlaying the calvariae of nude mice. The results demonstrated that the average tumor volume of SCC25 cells with 7ND protein was similar to the average volume of tumors formed by untreated SCC25 cells. Flow cytometric analysis suggested that the CD14+ subpopulation in the bone marrow of 7ND-treated mice was reduced compared with that of untreated mice. Micro-computed tomography imaging revealed significantly less bone resorption in the calvariae injected with SCC25 cells plus the 7ND protein. Taken together, the results of the present study demonstrated the potential therapeutic value of the 7ND protein. The 7ND MCP-1 variant not only functions in vitro to inhibit osteoclast differentiation, but also reduces the progression of bone invasion by OSCC cells in vivo.

In this paper, we consider the application of the h-p version finite element method in analysis of hydraulic structures by using the FEM computational software StressCheck of American ESRD (Engineering Software Research and Development) company as the computational tool. We choose a three dimensional concrete gravity dam as the computational model and compute the maximum displacement and the first principal stress of the concrete gravity dam. The results show that the h-p version finite element method is effective and reliable in analysis of hydraulic structures for the model chosen, and we obtained faster convergence rate, higher precision and smaller error by using the h-p version finite element method than by using p-version and h-version finite element method.

This paper presents a technique for processing Terahertz radar reflector by SPDT (Single Point Diamond Turning) based on LODTM (Large Optics Diamond Turning Machine). This technique applies single crystal diamond cutting tools for ultra-precision machining, and thus could obtain high-precision optical mirror, which could be used as the Terahertz radar reflectors. An experiment for aluminum sample had been done to demonstrate the availability of the technique, and a pair of Terahertz radar reflectors were obtained. The precision of the reflectors, detected through precision coordinate measuring technology, was better than the designed requirement. The experiment results showed that Terahertz radar reflectors generated by deterministic ultra-precision machining technique based on LODTM would have advantages in figure accuracy and roughness and so on, which could be helpful to improve the precision and low the cost of Terahertz radar system.

Background Rabies is a global fatal infectious viral disease that is characterized by a high mortality after onset of clinical symptoms. Recently, there has been an increase in the incidence of rabies in China. The aim of this study was to investigate the incidence of human rabies and characterize the rabies virus nucleoprotein gene in dogs sampled from Fujian Province, Southeast China from 2002 to 2012. Methods Data pertaining to human rabies cases in Fujian Province during the period from 2002 through 2012 were collected, and the epidemiological profiles were described. The saliva and brain specimens were collected from dogs in Quanzhou, Longyan and Sanming cities of the province, and the rabies virus antigen was determined in the canine saliva specimens using an ELISA assay. Rabies virus RNA was extracted from canine brain specimens, and rabies virus nucleoprotein gene was amplified using a nested RT-PCR assay, followed by sequencing and genotyping. Results A total of 226 human rabies cases were reported in Fujian Province from 2002 to 2012, in which 197 cases were detected in three cities of Quanzhou, Longyan and Sanming. ELISA assay revealed positive rabies virus antigen in six of eight rabid dogs and 165 of 3492 seemingly healthy dogs. The full-length gene fragment of the rabies virus nucleoprotein gene was amplified from the brain specimens of seven rabid dogs and 12 seemingly healthy dogs. Sequence alignment and phylogenetic analysis revealed that these 19 rabies virus nucleoprotein genes all belonged to genotype I, and were classified into three genetic groups. Sequencing analysis showed a 99.7% to 100% intra-group and an 86.4% to 89.3% inter-group homology. Conclusions This study is the first description pertaining to the epidemiological characteristics of human rabies cases and characterization of the rabies virus nucleoprotein gene in dogs in Fujian Province, Southeast China. Our findings may provide valuable knowledge for the development of strategies targeting the prevention and control of rabies.

Improved synthesis of 4-benzylidene-2,6-di-tert-butylcyclohexa-2,5-dienone has been developed. The dropwise addition of secondary amines was shown to reduce the dosages of amines drastically. In optimized conditions, the dosages of the catalysts were only 0.3–0.5 M of 2,6-di-tert-butylphenol. Removing the water generated in the step of Mannich base formation was found to hugely accelerate the whole reaction and improve the product yield. The catalytic activity of several annular secondary amines including morpholine and piperidine in this reaction has been researched. Most of the amines led to good yields. Using this method, 2,6-di-tert-butylphenol reacted with a wide range of aromatic aldehydes to produce nine diverse 4-benzylidene-2,6-di-tert-butylcyclohexa-2,5-dienone derivatives of up to 75 % yield.

Electronic commerce recommendation system can effectively retain customers, effective means to improve the electronic commerce system sales. This paper first analyzes the E-commerce recommender system based on ontology, and applies it to the clothing e-commerce website customer relationship management and personalized commodity recommendation; semantic structure through ontology has to commodity recommendation. The paper presents design and implementation of E-commerce recommendation system based on ontology technology so as to effectively improve customer satisfaction.

the article introduces theelectric car charger control circuit design thinking and ideas, the controlcircuit to be able to with the front-end circuit switching power supply and MCUto cooperate to complete the following phases the constant current and constantvoltage charging battery automatic conversion, and stable in each phase of thecurrent value or the voltage value. Analyze the circuit module, includingsampling module, PWM signal module, proportional amplifier module, PIadjustment module.

Through analysis and comparison of existing charging method works , adding more links constant current charging and constant voltage charging on the basis of the three-stage charging mode is proposed to receive more in line with rechargeable batteries five-phase characteristic curve charging mode. By scaling the control circuit and the PI regulator circuits use the charging current value and the constant voltage is sampled , a constant voltage corresponding to the error value to be compared and outputs the PWM control chip SG3525, causing the output current of the front end circuit chip , the regulation voltage , the error is gradually reduced until it reaches the steady-state output . 1 key components - integrated operational amplifier selection Integrated operational amplifier control circuit for the main components , essentially the entire op-amp circuits are designed to carry around , so choose the op amp circuit is particularly important . From the foregoing analysis, the current control and voltage control portion of each part requires three op amp ( both as an amplifier , a PI controller is used ) , the entire control circuit requires access to six integrated amplifier . Out of circuit integration considerations, decided to use a quad op amp manifold and a dual op amp with the completion of the manifold . By screening and the corresponding parameters available on the TI (TEXAS INSTRUMENTS TI ) website , and ultimately determine the use of quad op amp LF347 and dual op amp TLC2272.

Ontology technology is the foundation of the semantic Web, and provides support for the definition of domain ontology to the clothing e-commerce direct knowledge base, so as to realize the electronic commerce platform based on domain knowledge. In this paper, the design of the clothing network marketing e-commerce platform is an integrated product sales, product management, marketing and sales information entrance, marketing, customer relationship management and other functional modules operating platform. The paper presents application of ontology technology in building knowledge base of e-commerce system in direct selling clothing network. Experimental results show that the proposed application technology has high efficiency.

The objectives of this work were to compare the performance of two variable selection methods, namely, Monte Carlo–uninformative variable elimination (MC-UVE) and successive projections algorithm combined with partial least squares regression (PLSR), multiple linear regression (MLR), and least squares–support vector machine (LS-SVM) for the measurement of soil nitrogen (N), organic carbon (OC), available phosphorous (P), and available potassium (K) using near-infrared (NIR) spectroscopy, and provide interpretation for the effective variables. A total of 198 soil samples collected from nine towns in Wencheng County, People’s Republic of China, were scanned by a Fourier-type NIR spectrometer. The entire data set was split randomly into calibration set (62%), validation set (19%), and prediction set (19%). The calibration set was used to build calibration models with a number of spectral variables optimized by the validation set. The prediction set was used for independent prediction of the established models. The proposed combination of MC-UVE-LS-SVM achieved the optimal prediction performance compared with PLSR, LS-SVM, successive projections algorithm–MLR, and MC-UVE-PLSR. The values of coefficient of determination (R) and residual prediction deviation were 0.88, 0.89, 0.59, and 0.75, and 2.9, 3.1, 1.5, and 2.0 for N, OC, P and K, respectively. The results showed that MC-UVE was able to select important variables from the NIR spectra, and LS-SVM was preferable to linear PLSR and MLR for the prediction of soil properties in this work. Analysis of effective variables indicated that: some of the effective variables of N and OC were directly associated with their functional groups, whereas some impacted on the prediction accuracy by measuring soil moisture content. Soil P and K were found to be measurable with different levels of agreement, which was partly attributed to the covariation of moisture content and illite in soil.

The ichthyofauna of mountain streams in the Danzhangshan Nature Reserve (DNR) and the Raoheyuan Nature Reserve (RNR) was investigated during 2008. A total of 385 samples were collected and classified into seven families and 14 species from the two nature reserves. There were 12 species belonging to seven families in the RNR, while eight species from four families were collected in the DNR. Overall, six species were found to be endemic to China, representing five families. The relative abundance of endemic species to China was higher in the RNR than in the DNR. Current threats to conservation of fishes in both nature reserves were reviewed and management solutions are suggested. Key words: Fish, species, diversity, conservation, nature reserve, China.