315 results on '"Jensen, Magnus T"'
Search Results
2. Altered cardiac autonomic functioning associates with self-disorders in schizophrenia
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Sandsten, Karl Erik, Jensen, Magnus T., Saebye, Ditte, Null, Kaylee, Northoff, Georg, and Parnas, Josef
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- 2024
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3. Electrocardiographic markers in patients with type 2 diabetes and the role of diabetes duration
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Isaksen, Jonas L., Sivertsen, Christian B., Jensen, Christian Zinck, Graff, Claus, Linz, Dominik, Ellervik, Christina, Jensen, Magnus T., Jørgensen, Peter G., and Kanters, Jørgen K.
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- 2024
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4. Ratio of transmitral early filling velocity to diastolic strain rate and prognosis in type-1 diabetes
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Lassen, Mats Christian Højbjerg, Biering-Sørensen, Tor, Jørgensen, Peter Godsk, Bahrami, Hashmat S.Z., Andersen, Henrik Ullits, Rossing, Peter, and Jensen, Magnus T.
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- 2024
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5. Should workers be physically active after work? Associations of leisure-time physical activity with cardiovascular and all-cause mortality across occupational physical activity levels—An individual participant data meta-analysis
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Cillekens, Bart, Coenen, Pieter, Huysmans, Maaike A., Holtermann, Andreas, Troiano, Richard P., Mork, Paul Jarle, Krokstad, Steinar, Clays, Els, De Bacquer, Dirk, Aadahl, Mette, Kårhus, Line Lund, Sjøl, Anette, Bo Andersen, Lars, Kauhanen, Jussi, Voutilainen, Ari, Pulsford, Richard, Stamatakis, Emmanuel, Goldbourt, Uri, Peters, Annette, Thorand, Barbara, Rosengren, Annika, Björck, Lena, Sprow, Kyle, Franzon, Kristin, Rodriguez-Barranco, Miguel, Luján-Barroso, Leila, Alfredsson, Lars, Bahls, Martin, Ittermann, Till, Wanner, Miriam, Bopp, Matthias, Marott, Jacob Louis, Schnohr, Peter, Nordestgaarda, Børge G., Dalene, Knut Eirik, Ekelund, Ulf, Clausen, Johan, Jensen, Magnus T., Petersen, Christina Bjørk, Krause, Niklas, Twisk, Jos, van Mechelen, Willem, and van der Beek, Allard J.
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- 2024
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6. Left Atrial Strain Predicts Subclinical Atrial Fibrillation Detected by Long-term Continuous Monitoring in Elderly High-Risk Individuals
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Olsen, Flemming Javier, Diederichsen, Søren Zöga, Jørgensen, Peter Godsk, Jensen, Magnus T., Dahl, Anders, Landler, Nino Emanuel, Graff, Claus, Brandes, Axel, Krieger, Derk, Haugan, Ketil, Køber, Lars, Højberg, Søren, Svendsen, Jesper Hastrup, and Biering-Sørensen, Tor
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- 2024
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7. Height Explains Sex Difference in Atrial Fibrillation Risk: Copenhagen General Population Study
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Marott, Jacob Louis, Jensen, Magnus T., Benn, Marianne, Knegt, Martina Chantal de, O’Keefe, James H., Lavie, Carl J., Schnohr, Peter, Nordestgaard, Børge Grønne, and Jensen, Gorm Boje
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- 2023
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8. Accuracy, analysis time, and reproducibility of dedicated 4D echocardiographic left atrial volume quantification software
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Olsen, Flemming Javier, Bertelsen, Litten, Vejlstrup, Niels, Bjerregaard, Caroline Løkke, Diederichsen, Søren Zöga, Jørgensen, Peter Godsk, Jensen, Magnus T., Dahl, Anders, Landler, Nino Emmanuel, Graff, Claus, Brandes, Axel, Krieger, Derk, Haugan, Ketil, Køber, Lars, Højberg, Søren, Svendsen, Jesper Hastrup, and Biering-Sørensen, Tor
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- 2022
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9. Maternal Diabetes and Cardiac Left Ventricular Structure and Function in the Infant: A Copenhagen Baby Heart Study.
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Ghouse, Jonas, Hansson, Magdalena, Vøgg, Ruth Ottilia B., Sillesen, Anne-Sophie, Pærregaard, Sofie, Raja, Anna Axelsson, Vejlstrup, Niels, Frikke-Schmidt, Ruth, Øyen, Nina, Kulkarni, Aparna, Jensen, Magnus T., Jørgensen, Finn Stener, Sundberg, Karin, Petersen, Olav B., Wohlfahrt, Jan, Damm, Peter, Olesen, Morten Salling, Mathiesen, Elisabeth R., Iversen, Kasper, and Bundgaard, Henning
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GESTATIONAL diabetes ,MITRAL valve ,PRENATAL exposure ,HEART abnormalities ,MATERNAL exposure - Abstract
OBJECTIVE: Prenatal exposure to maternal diabetes is associated with an increased risk of offspring heart defects. We evaluated associations with subtle infant cardiac changes. RESEARCH DESIGN AND METHODS: In a cohort of 25,486 infants with transthoracic echocardiography within 60 days of birth, we investigated associations between maternal preexisting diabetes and gestational diabetes mellitus (GDM) and infant left ventricular (LV) structural and functional parameters, using linear regression to estimate adjusted mean differences (aMDs) between groups. RESULTS: Infants exposed to maternal preexisting diabetes (n = 198) had thicker LV posterior walls (aMD 0.19 mm; 95% CI 0.11, 0.27), smaller LV internal diameters in systole (aMD −0.27 mm; 95% CI −0.45, −0.18) and diastole (aMD −0.37 mm; 95% CI −0.59, −0.09), reduced stroke volumes (aMD −0.36 mL; 95% CI −0.61, −0.11), and increased heart rates (aMD 3.14 bpm; 95% CI 1.10, 6.18) and mitral valve early peak velocities (aMD 2.17 cm/s; 95% CI 0.31, 4.04) than unexposed infants (n = 24,639). Infants born to mothers with GDM (n = 649) had significantly smaller LV internal diameters in systole (aMD −0.13 mm; 95% CI −0.22, −0.03) and similar structural and functional changes as children exposed to preexisting diabetes, albeit with smaller nonsignificant aMDs. Higher third-trimester HbA
1c levels were associated with smaller LV internal diameters and stroke volumes in infants exposed to preexisting diabetes and with lower heart rates in infants exposed to GDM. CONCLUSIONS: Maternal preexisting diabetes and, to a lesser extent, GDM were associated with changes in infant LV structure and function. [ABSTRACT FROM AUTHOR]- Published
- 2024
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10. The novel inflammatory biomarker GlycA and triglyceride-rich lipoproteins are associated with the presence of subclinical myocardial dysfunction in subjects with type 1 diabetes mellitus
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Puig-Jové, Carlos, Julve, Josep, Castelblanco, Esmeralda, Julián, M Teresa, Amigó, Núria, Andersen, Henrik U, Ahluwalia, Tarunveer S, Rossing, Peter, Mauricio, Dídac, Jensen, Magnus T, and Alonso, Núria
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- 2022
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11. Prognostic Value of Early Systolic Lengthening by Strain Imaging in Type 2 Diabetes
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Brainin, Philip, Biering-Sørensen, Tor, Jensen, Magnus T., Møgelvang, Rasmus, Fritz-Hansen, Thomas, Vilsbøll, Tina, Rossing, Peter, and Jørgensen, Peter Godsk
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- 2021
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12. Effect of dapagliflozin on cardiac function in people with type 2 diabetes and albuminuria – A double blind randomized placebo-controlled crossover trial
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Eickhoff, Mie K., Olsen, Flemming J., Frimodt-Møller, Marie, Diaz, Lars J., Faber, Jens, Jensen, Magnus T., Rossing, Peter, and Persson, Frederik
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- 2020
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13. Even mild mitral regurgitation is associated with incident atrial fibrillation in the general population
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Yafasov, Marat, Olsen, Flemming Javier, Shabib, Ali, Skaarup, Kristoffer Grundtvig, Lassen, Mats Christian Højbjerg, Johansen, Niklas Dyrby, Jensen, Magnus T, Jensen, Gorm Boje, Schnohr, Peter, Møgelvang, Rasmus, Biering-Sørensen, Tor, Yafasov, Marat, Olsen, Flemming Javier, Shabib, Ali, Skaarup, Kristoffer Grundtvig, Lassen, Mats Christian Højbjerg, Johansen, Niklas Dyrby, Jensen, Magnus T, Jensen, Gorm Boje, Schnohr, Peter, Møgelvang, Rasmus, and Biering-Sørensen, Tor
- Abstract
Aims Mitral regurgitation (MR) can be difficult to quantify. We sought to investigate whether the MR jet area to left atrial (LA) area ratio (MR/LA ratio) method for quantifying MRs can be used to predict incident atrial fibrillation (AF) in the general population. Methods and results The study included 4466 participants from the 5th Copenhagen City Heart Study, a prospective general population study, who underwent transthoracic echocardiography. MR jet area was measured and indexed to LA area. The endpoint was incident AF. MR was quantified in 4042 participants (mean age: 57 years, 43% men). Of these, 198 (4.9%) developed AF during a median follow-up period of 5.3 years (interquartile range: 4.4–6.1 years). MR was present in 1938 participants (48%) including 1593 (39%) trace/mild MRs (MR/LA ratio ≤ 20% and ≤4 cm2). In unadjusted analysis, MR/LA ratio was associated with incident AF [HR: 1.06 (1.00–1.13), P = 0.042 per 5% increase] but not after adjusting for CHARGE-AF score. However, the association was modified by age (P for interaction = 0.034), such that MR/LA ratio was associated with AF only in participants ≤ 73 years. In these participants, MR/LA ratio ‘was’ independently associated with AF after adjusting for CHARGE-AF score [HR: 1.14 (1.06–1.24), P = 0.001, per 5% increase]. This finding persisted when restricting the analysis to participants without moderate or severe MR and normal LA size [HR: 1.35 (1.09–1.68), P = 0.005, per 5% increase]. Conclusion MR, including even trace regurgitations quantified by MR/LA ratio, is independently associated with incident AF in individuals ≤ 73 years of age., Aims Mitral regurgitation (MR) can be difficult to quantify. We sought to investigate whether the MR jet area to left atrial (LA) area ratio (MR/LA ratio) method for quantifying MRs can be used to predict incident atrial fibrillation (AF) in the general population. Methods and results The study included 4466 participants from the 5th Copenhagen City Heart Study, a prospective general population study, who underwent transthoracic echocardiography. MR jet area was measured and indexed to LA area. The endpoint was incident AF. MR was quantified in 4042 participants (mean age: 57 years, 43% men). Of these, 198 (4.9%) developed AF during a median follow-up period of 5.3 years (interquartile range: 4.4–6.1 years). MR was present in 1938 participants (48%) including 1593 (39%) trace/mild MRs (MR/LA ratio ≤ 20% and ≤4 cm2). In unadjusted analysis, MR/LA ratio was associated with incident AF [HR: 1.06 (1.00–1.13), P = 0.042 per 5% increase] but not after adjusting for CHARGE-AF score. However, the association was modified by age (P for interaction = 0.034), such that MR/LA ratio was associated with AF only in participants ≤ 73 years. In these participants, MR/LA ratio ‘was’ independently associated with AF after adjusting for CHARGE-AF score [HR: 1.14 (1.06–1.24), P = 0.001, per 5% increase]. This finding persisted when restricting the analysis to participants without moderate or severe MR and normal LA size [HR: 1.35 (1.09–1.68), P = 0.005, per 5% increase]. Conclusion MR, including even trace regurgitations quantified by MR/LA ratio, is independently associated with incident AF in individuals ≤ 73 years of ag
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- 2024
14. An echocardiographic substrate for dyspnea identifies high risk patients with type 2 diabetes
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Jørgensen, Peter G., Schou, Morten, Biering-Sørensen, Tor, Mogelvang, Rasmus, Fritz-Hansen, Thomas, Vilsbøll, Tina, Rossing, Peter, and Jensen, Magnus T.
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- 2019
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15. Altered Cardiac Autonomic Functioning Associates with Self-Disorders in Schizophrenia
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Sandsten, Karl Erik, primary, Jensen, Magnus T., additional, Saebye, Ditte, additional, -, Kaylee, additional, Northoff, Georg, additional, and Parnas, Josef, additional
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- 2024
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16. Even mild mitral regurgitation is associated with incident atrial fibrillation in the general population
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Yafasov, Marat, primary, Olsen, Flemming Javier, additional, Shabib, Ali, additional, Skaarup, Kristoffer Grundtvig, additional, Lassen, Mats Christian Højbjerg, additional, Johansen, Niklas Dyrby, additional, Jensen, Magnus T, additional, Jensen, Gorm Boje, additional, Schnohr, Peter, additional, Møgelvang, Rasmus, additional, and Biering-Sørensen, Tor, additional
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- 2023
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17. Ratio of transmitral early filling velocity to diastolic strain rate and prognosis in type-1 diabetes
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Lassen, Mats Christian Højbjerg, primary, Biering-Sørensen, Tor, additional, Jørgensen, Peter Godsk, additional, Bahrami, Hashmat S.Z., additional, Andersen, Henrik Ullits, additional, Rossing, Peter, additional, and Jensen, Magnus T., additional
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- 2023
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18. Type 1 diabetes is associated with T-wave morphology changes. The Thousand & 1 Study
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Isaksen, Jonas L., Graff, Claus, Ellervik, Christina, Jensen, Jan Skov, Andersen, Henrik Ullits, Rossing, Peter, Kanters, Jorgen K., and Jensen, Magnus T.
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- 2018
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19. The ESC Working Group on e-Cardiology.
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Arroyo, Ruben Casado, Jensen, Magnus T, Dilaveris, Polychronis, Locati, Emanuela T, and Lucia, Raffaele De
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SCIENCE education ,DIGITAL health ,INFORMATION technology ,TELECOMMUNICATION ,DIGITAL transformation ,CARDIOLOGISTS - Abstract
The European Heart Journal's article titled "The ESC Working Group on e-Cardiology" discusses the mission and activities of the ESC Working Group on e-Cardiology. The group was established in 1996 to promote the use of information technology in cardiology and aims to integrate scientific research and education in the field of e-cardiology. The group focuses on advancing computational, digital, and mobile technology in cardiovascular healthcare and collaborates with other ESC bodies on digital health-related matters. The group publishes position papers, organizes conferences and webinars, and promotes the adoption of advanced digital technologies in cardiology. They also invite individuals interested in e-cardiology and digital health to join their community. [Extracted from the article]
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- 2024
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20. Echocardiography improves prediction of major adverse cardiovascular events in a population with type 1 diabetes and without known heart disease: the Thousand & 1 Study
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Jensen, Magnus T., Sogaard, Peter, Gustafsson, Ida, Bech, Jan, Hansen, Thomas F., Almdal, Thomas, Theilade, Simone, Biering-Sørensen, Tor, Jørgensen, Peter G., Galatius, Søren, Andersen, Henrik U., and Rossing, Peter
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- 2019
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21. Use of sugar in coffee and tea and long-term risk of mortality in older adult Danish men: 32 years of follow-up from a prospective cohort study
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Treskes, Roderick W., primary, Clausen, Johan, additional, Marott, Jacob L., additional, Jensen, Gorm B., additional, Holtermann, Andreas, additional, Gyntelberg, Finn, additional, and Jensen, Magnus T., additional
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- 2023
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22. Prognostic value of myocardial performance index in individuals with type 1 and type 2 diabetes: Thousand&1 and Thousand&2 studies
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Bahrami, Hashmat Sayed Zohori, primary, Jørgensen, Peter Godsk, additional, Hove, Jens Dahlgaard, additional, Dixen, Ulrik, additional, Biering-Sørensen, Tor, additional, Rossing, Peter, additional, and Jensen, Magnus T, additional
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- 2023
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23. MR-proANP and incident cardiovascular disease in patients with type 2 diabetes with and without heart failure with preserved ejection fraction
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Jensen, Jesper, Schou, Morten, Kistorp, Caroline, Faber, Jens, Hansen, Tine W., Jensen, Magnus T., Andersen, Henrik U., Rossing, Peter, Vilsbøll, Tina, and Jørgensen, Peter G.
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- 2020
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24. Cardiac depolarization and repolarization markers in people with type 2 diabetes
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Isaksen, Jonas L., primary, Sivertsen, Christian B., additional, Jensen, Christian Zinck, additional, Graff, Claus, additional, Linz, Dominik, additional, Ellervik, Christina, additional, Jensen, Magnus T., additional, Jørgensen, Peter G., additional, and Kanters, Jørgen K., additional
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- 2023
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25. Impact of type 2 diabetes and duration of type 2 diabetes on cardiac structure and function
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Jørgensen, Peter G., Jensen, Magnus T., Mogelvang, Rasmus, Fritz-Hansen, Thomas, Galatius, Søren, Biering-Sørensen, Tor, Storgaard, Heidi, Vilsbøll, Tina, Rossing, Peter, and Jensen, Jan S.
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- 2016
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26. Retinopathy is associated with impaired myocardial function assessed by advanced echocardiography in type 1 diabetes patients – The Thousand & 1 Study
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Nouhravesh, Nina, Andersen, Henrik U., Jensen, Jan S., Rossing, Peter, and Jensen, Magnus T.
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- 2016
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27. Changes in Cardiac Morphology and Function in Individuals With Diabetes Mellitus: The UK Biobank Cardiovascular Magnetic Resonance Substudy
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Jensen, Magnus T., Fung, Kenneth, Aung, Nay, Sanghvi, Mihir M., Chadalavada, Sucharitha, Paiva, Jose M., Khanji, Mohammed Y., de Knegt, Martina C., Lukaschuk, Elena, Lee, Aaron M., Barutcu, Ahmet, Maclean, Edd, Carapella, Valentina, Cooper, Jackie, Young, Alistair, Piechnik, Stefan K., Neubauer, Stefan, and Petersen, Steffen E.
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- 2019
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28. Epicardial adipose tissue predicts incident cardiovascular disease and mortality in patients with type 2 diabetes
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Christensen, Regitse H., von Scholten, Bernt Johan, Hansen, Christian S., Jensen, Magnus T., Vilsbøll, Tina, Rossing, Peter, and Jørgensen, Peter G.
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- 2019
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29. Diabetes and heart failure associations in women and men : Results from the MORGAM consortium
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Chadalavada, Sucharitha, Reinikainen, Jaakko, Andersson, Jonas, Di Castelnuovo, Augusto, Iacoviello, Licia, Jousilahti, Pekka, Kårhus, Line Lund, Linneberg, Allan, Söderberg, Stefan, Tunstall-Pedoe, Hugh, Lekadir, Karim, Aung, Nay, Jensen, Magnus T., Kuulasmaa, Kari, Niiranen, Teemu J., Petersen, Steffen E., Chadalavada, Sucharitha, Reinikainen, Jaakko, Andersson, Jonas, Di Castelnuovo, Augusto, Iacoviello, Licia, Jousilahti, Pekka, Kårhus, Line Lund, Linneberg, Allan, Söderberg, Stefan, Tunstall-Pedoe, Hugh, Lekadir, Karim, Aung, Nay, Jensen, Magnus T., Kuulasmaa, Kari, Niiranen, Teemu J., and Petersen, Steffen E.
- Abstract
Background: Diabetes and its cardiovascular complications are a growing concern worldwide. Recently, some studies have demonstrated that relative risk of heart failure (HF) is higher in women with type 1 diabetes (T1DM) than in men. This study aims to validate these findings in cohorts representing five countries across Europe. Methods: This study includes 88,559 (51.8% women) participants, 3,281 (46.3% women) of whom had diabetes at baseline. Survival analysis was performed with the outcomes of interest being death and HF with a follow-up time of 12 years. Sub-group analysis according to sex and type of diabetes was also performed for the HF outcome. Results: 6,460 deaths were recorded, of which 567 were amongst those with diabetes. Additionally, HF was diagnosed in 2,772 individuals (446 with diabetes). A multivariable Cox proportional hazard analysis showed that there was an increased risk of death and HF (hazard ratio (HR) of 1.73 [1.58–1.89] and 2.12 [1.91–2.36], respectively) when comparing those with diabetes and those without. The HR for HF was 6.72 [2.75–16.41] for women with T1DM vs. 5.80 [2.72–12.37] for men with T1DM, but the interaction term for sex differences was insignificant (p for interaction 0.45). There was no significant difference in the relative risk of HF between men and women when both types of diabetes were combined (HR 2.22 [1.93–2.54] vs. 1.99 [1.67–2.38] respectively, p for interaction 0.80). Conclusion: Diabetes is associated with increased risks of death and heart failure, and there was no difference in relative risk according to sex.
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- 2023
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30. Diabetes and heart failure associations in women and men:Results from the MORGAM consortium
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Chadalavada, Sucharitha, Reinikainen, Jaakko, Andersson, Jonas, Di Castelnuovo, Augusto, Iacoviello, Licia, Jousilahti, Pekka, Kårhus, Line Lund, Linneberg, Allan, Söderberg, Stefan, Tunstall-Pedoe, Hugh, Lekadir, Karim, Aung, Nay, Jensen, Magnus T., Kuulasmaa, Kari, Niiranen, Teemu J., Petersen, Steffen E., Chadalavada, Sucharitha, Reinikainen, Jaakko, Andersson, Jonas, Di Castelnuovo, Augusto, Iacoviello, Licia, Jousilahti, Pekka, Kårhus, Line Lund, Linneberg, Allan, Söderberg, Stefan, Tunstall-Pedoe, Hugh, Lekadir, Karim, Aung, Nay, Jensen, Magnus T., Kuulasmaa, Kari, Niiranen, Teemu J., and Petersen, Steffen E.
- Abstract
Background: Diabetes and its cardiovascular complications are a growing concern worldwide. Recently, some studies have demonstrated that relative risk of heart failure (HF) is higher in women with type 1 diabetes (T1DM) than in men. This study aims to validate these findings in cohorts representing five countries across Europe. Methods: This study includes 88,559 (51.8% women) participants, 3,281 (46.3% women) of whom had diabetes at baseline. Survival analysis was performed with the outcomes of interest being death and HF with a follow-up time of 12 years. Sub-group analysis according to sex and type of diabetes was also performed for the HF outcome. Results: 6,460 deaths were recorded, of which 567 were amongst those with diabetes. Additionally, HF was diagnosed in 2,772 individuals (446 with diabetes). A multivariable Cox proportional hazard analysis showed that there was an increased risk of death and HF (hazard ratio (HR) of 1.73 [1.58–1.89] and 2.12 [1.91–2.36], respectively) when comparing those with diabetes and those without. The HR for HF was 6.72 [2.75–16.41] for women with T1DM vs. 5.80 [2.72–12.37] for men with T1DM, but the interaction term for sex differences was insignificant (p for interaction 0.45). There was no significant difference in the relative risk of HF between men and women when both types of diabetes were combined (HR 2.22 [1.93–2.54] vs. 1.99 [1.67–2.38] respectively, p for interaction 0.80). Conclusion: Diabetes is associated with increased risks of death and heart failure, and there was no difference in relative risk according to sex.
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- 2023
31. Prognostic value of myocardial performance index in individuals with type 1 and type 2 diabetes:Thousand&1 and Thousand&2 studies
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Bahrami, Hashmat Sayed Zohori, Jørgensen, Peter Godsk, Hove, Jens Dahlgaard, Dixen, Ulrik, Biering-Sørensen, Tor, Rossing, Peter, Jensen, Magnus T., Bahrami, Hashmat Sayed Zohori, Jørgensen, Peter Godsk, Hove, Jens Dahlgaard, Dixen, Ulrik, Biering-Sørensen, Tor, Rossing, Peter, and Jensen, Magnus T.
- Abstract
AIMS: Cardiovascular disease (CVD) is the leading cause of mortality and morbidity in type 1 (T1D) and type 2 diabetes (T2D). Despite diabetes affects the myocardium, risk prediction models do not include myocardial function parameters. Myocardial performance index (MPI) reflects left ventricular function. The prognostic value of MPI has not been evaluated in large-scale diabetes populations.METHODS AND RESULTS: We evaluated two prospective cohort studies: Thousand&1 (1093 individuals with T1D) and Thousand&2 (1030 individuals with T2D). Clinical data, including echocardiography, were collected at baseline. We collected follow-up data from national registries. We defined major adverse cardiovascular events (MACE) as incident events of hospital admission for acute coronary syndrome, heart failure, stroke, or all-cause mortality. For included individuals (56% male, 54 ± 15 years, MPI 0.51 ± 0.1, 63% T1D), follow-up was 100% after median of 5.3 years (range: 4.8-6.3). MPI was associated with MACE (HR 1.2, 95%CI 1.0-1.3, P = 0.012, per 0.10-unit increase) and heart failure (HR 1.3, 95%CI 1.1-1.6, P = 0.005, per 0.10-unit increase) after adjusting for clinical and echocardiographic variables. MPI predicted MACE and heart failure better in T1D than T2D (P = 0.031 for interaction). MPI added discriminatory power to the Steno T1 Risk Engine, based on clinical characteristics, in predicting MACE [area under the curve (AUC) from 0.77 to 0.79, P = 0.030] and heart failure (AUC from 0.77 to 0.83, P = 0.009) in T1D.CONCLUSION: MPI is independently associated with MACE and heart failure in T1D but not T2D and improves prediction in T1D. Echocardiographic assessment in T1D may enhance risk prediction.
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- 2023
32. Height Explains Sex Difference in Atrial Fibrillation Risk:Copenhagen General Population Study
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Marott, Jacob Louis, Jensen, Magnus T., Benn, Marianne, Knegt, Martina Chantal de, O'Keefe, James H., Lavie, Carl J., Schnohr, Peter, Nordestgaard, Børge Grønne, Jensen, Gorm Boje, Marott, Jacob Louis, Jensen, Magnus T., Benn, Marianne, Knegt, Martina Chantal de, O'Keefe, James H., Lavie, Carl J., Schnohr, Peter, Nordestgaard, Børge Grønne, and Jensen, Gorm Boje
- Abstract
Objective: To test the hypothesis that the increased risk of atrial fibrillation (AF) in men compared with women is explained by height. Methods: From the Copenhagen General Population Study, we included 106,207 individuals (47,153 men and 59,054 women) from 20 to 100 years of age, without a prior diagnosis of AF, examined between November 25, 2003, and April 28, 2015. The main outcome was AF incidence from national hospital registers until April 2018. The association of risk factors with AF incidence was assessed by cause-specific Cox proportional hazards regression and Fine-Gray subdistribution hazards regression analysis. Results: During a maximum of 14.4 years of follow-up (median, 8.9 years), incident AF was observed in 3449 men and 2772 women with 845 (95% CI, 815 to 875) and 514 (95% CI, 494 to 535) events per 100,000 person-years, respectively. The age-adjusted hazard of incident AF was 63% (95% CI, 55% to 72%) higher in men compared with women. Risk factors for AF were generally similar in men and women, except men were taller than women (179 cm vs 166 cm, respectively; P<.001). When controlling for height, the difference in hazard of incident AF between sexes disappeared. For population attributable risk of AF, height was the most important risk factor investigated and explained 21% and 19% of the risk of incident AF in men and women, respectively. Conclusion: A 63% higher risk of incident AF in men compared with women is explained by differences in height.
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- 2023
33. Changes in Myocardial Tissue Velocities over a Decade:The Copenhagen City Heart Study
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Lassen, Mats Christian Højbjerg, Lind, Jannie Nørgaard, Sengeløv, Morten, Skaarup, Kristoffer Grundtvig, Johansen, Niklas Dyrby, Qasim, Atif N., Jensen, Magnus T., Jensen, Gorm Boje, Schnohr, Peter, Møgelvang, Rasmus, Biering-Sørensen, Tor, Lassen, Mats Christian Højbjerg, Lind, Jannie Nørgaard, Sengeløv, Morten, Skaarup, Kristoffer Grundtvig, Johansen, Niklas Dyrby, Qasim, Atif N., Jensen, Magnus T., Jensen, Gorm Boje, Schnohr, Peter, Møgelvang, Rasmus, and Biering-Sørensen, Tor
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- 2023
34. Diabetes and heart failure associations in women and men: Results from the MORGAM consortium
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Chadalavada, Sucharitha, primary, Reinikainen, Jaakko, additional, Andersson, Jonas, additional, Di Castelnuovo, Augusto, additional, Iacoviello, Licia, additional, Jousilahti, Pekka, additional, Kårhus, Line Lund, additional, Linneberg, Allan, additional, Söderberg, Stefan, additional, Tunstall-Pedoe, Hugh, additional, Lekadir, Karim, additional, Aung, Nay, additional, Jensen, Magnus T., additional, Kuulasmaa, Kari, additional, Niiranen, Teemu J., additional, and Petersen, Steffen E., additional
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- 2023
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35. Changes in Myocardial Tissue Velocities Over a Decade: The Copenhagen City Heart Study
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Lassen, Mats Christian Højbjerg, primary, Lind, Jannie Nørgaard, additional, Sengeløv, Morten, additional, Skaarup, Kristoffer Grundtvig, additional, Johansen, Niklas Dyrby, additional, Qasim, Atif N., additional, Jensen, Magnus T., additional, Jensen, Gorm Boje, additional, Schnohr, Peter, additional, Møgelvang, Rasmus, additional, and Biering-Sørensen, Tor, additional
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- 2023
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36. Arterial-ventricular coupling in type 1 diabetes: arterial stiffness is associated with impaired global longitudinal strain in type 1 diabetes patients—the Thousand & 1 Study
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Theilade, Simone, Rossing, Peter, Jensen, Jan S., and Jensen, Magnus T.
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- 2017
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37. Frailty in cardiology: definition, assessment and clinical implications for general cardiology. A consensus document of the Council for Cardiology Practice (CCP), Association for Acute Cardio Vascular Care (ACVC), Association of Cardiovascular Nursing and Allied Professions (ACNAP), European Association of Preventive Cardiology (EAPC), European Heart Rhythm Association (EHRA), Council on Valvular Heart Diseases (VHD), Council on Hypertension (CHT), Council of Cardio-Oncology (CCO), Working Group (WG) Aorta and Peripheral Vascular Diseases, WG e-Cardiology, WG Thrombosis, of the European Society of Cardiology, European Primary Care Cardiology Society (EPCCS)
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Richter, Dimitri, Guasti, Luigina, Walker, David, Lambrinou, Ekaterini, Lionis, Christos, Abreu, Ana, Savelieva, Irina, Fumagalli, Stefano, Bo, Mario, Rocca, Bianca, Jensen, Magnus T., Pierard, Luc, Sudano, Isabella, Aboyans, Victor, Asteggiano, Riccardo, University of Zurich, and Repositório da Universidade de Lisboa
- Subjects
Cardiovascular Nursing ,Consensus ,Epidemiology ,Cardiology ,Heart Valve Diseases ,610 Medicine & health ,Frailty in cardiovascular diseases ,Frailty management ,Neoplasms ,Frailty evaluation ,Humans ,Frailty components ,Frailty trajectory ,Aorta ,Nutrition ,Peripheral Vascular Diseases ,Disability ,Frailty digital health ,Frailty ,Primary Health Care ,Rehabilitation ,Multimorbidity ,Thrombosis ,Frailty prevention ,Hypertension ,10209 Clinic for Cardiology ,Frailty screening ,Frailty assessment ,Cardiology and Cardiovascular Medicine ,Frailty domains - Abstract
© The Author(s) 2021. Published by Oxford University Press on behalf of the European Society of Cardiology. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com, Frailty is a health condition leading to many adverse clinical outcomes. The relationship between frailty and advanced age, multimorbidity and disability has a significant impact on healthcare systems. Frailty increases cardiovascular (CV) morbidity and mortality both in patients with or without known CV disease. Though the recognition of this additional risk factor has become increasingly clinically relevant in CV diseases, uncertainty remains about operative definitions, screening, assessment, and management of frailty. Since the burdens of frailty components and domains may vary in the various CV diseases and clinical settings, the relevance of specific frailty-related aspects may be different. Understanding these issues may allow general cardiologists a clearer focus on frailty in CV diseases and thereby make more tailored clinical decisions and therapeutic choices in outpatients. Guidance on identification and management of frailty are sparse and an international consensus document on frailty in general cardiology is lacking. Moreover, new options linked with eHealth are going to better define and manage frailty. This consensus document on definition, assessment, clinical implications, and management of frailty provides an input to integrate strategies pre- and post-acute CV events with a comprehensive view including out of hospital, office-based diagnostic and therapeutic choices, and based on a multidisciplinary team approach (general cardiologists, nurses, and general practitioners).
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- 2021
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38. Heritability of resting heart rate and association with mortality in middle-aged and elderly twins
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Jensen, Magnus T, Wod, Mette, Galatius, Søren, Hjelmborg, Jacob B, Jensen, Gorm B, and Christensen, Kaare
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- 2018
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39. ESC Working Group on e-Cardiology Position Paper: accuracy and reliability of electrocardiogram monitoring in the detection of atrial fibrillation in cryptogenic stroke patients : In collaboration with the Council on Stroke, the European Heart Rhythm Association, and the Digital Health Committee
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Dilaveris, Polychronis E, Antoniou, Christos Konstantinos, Caiani, Enrico G, Casado-Arroyo, Ruben, Climent, Andreu Μ, Cluitmans, Matthijs, Cowie, Martin R, Doehner, Wolfram, Guerra, Federico, Jensen, Magnus T, Kalarus, Zbigniew, Locati, Emanuela Teresa, Platonov, Pyotr, Simova, Iana, Schnabel, Renate B, Schuuring, Mark, Tsivgoulis, Georgios, Lumens, Joost, Cardiology, ACS - Heart failure & arrhythmias, and Amsterdam Cardiovascular Sciences
- Abstract
The role of subclinical atrial fibrillation as a cause of cryptogenic stroke is unambiguously established. Long-term electrocardiogram (ECG) monitoring remains the sole method for determining its presence following a negative initial workup. This position paper of the European Society of Cardiology Working Group on e-Cardiology first presents the definition, epidemiology, and clinical impact of cryptogenic ischaemic stroke, as well as its aetiopathogenic association with occult atrial fibrillation. Then, classification methods for ischaemic stroke will be discussed, along with their value in providing meaningful guidance for further diagnostic efforts, given disappointing findings of studies based on the embolic stroke of unknown significance construct. Patient selection criteria for long-term ECG monitoring, crucial for determining pre-test probability of subclinical atrial fibrillation, will also be discussed. Subsequently, the two major classes of long-term ECG monitoring tools (non-invasive and invasive) will be presented, with a discussion of each method’s pitfalls and related algorithms to improve diagnostic yield and accuracy. Although novel mobile health (mHealth) devices, including smartphones and smartwatches, have dramatically increased atrial fibrillation detection post ischaemic stroke, the latest evidence appears to favour implantable cardiac monitors as the modality of choice; however, the answer to whether they should constitute the initial diagnostic choice for all cryptogenic stroke patients remains elusive. Finally, institutional and organizational issues, such as reimbursement, responsibility for patient management, data ownership, and handling will be briefly touched upon, despite the fact that guidance remains scarce and widespread clinical application and experience are the most likely sources for definite answers.
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- 2022
40. Diagnostic and prognostic value of the electrocardiogram in stable outpatients with type 2 diabetes
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Gregers, Mads C. T., primary, Schou, Morten, additional, Jensen, Magnus T., additional, Jensen, Jesper, additional, Petrie, Mark C., additional, Vilsbøll, Tina, additional, Goetze, Jens Peter, additional, Rossing, Peter, additional, and Jørgensen, Peter G., additional
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- 2022
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41. Potential role of conventional and speckle-tracking echocardiography in the screening of structural and functional cardiac abnormalities in elderly individuals: Baseline echocardiographic findings from the LOOP study
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Olsen, Flemming Javier, primary, Diederichsen, Søren Zöga, additional, Jørgensen, Peter Godsk, additional, Jensen, Magnus T., additional, Dahl, Anders, additional, Landler, Nino Emmanuel, additional, Graff, Claus, additional, Brandes, Axel, additional, Krieger, Derk, additional, Haugan, Ketil, additional, Køber, Lars, additional, Højberg, Søren, additional, Svendsen, Jesper Hastrup, additional, and Biering-Sørensen, Tor, additional
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- 2022
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42. Worldwide Disparities in Recovery of Cardiac Testing 1 Year Into COVID-19
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Einstein, Andrew J., primary, Hirschfeld, Cole, additional, Williams, Michelle C., additional, Vitola, Joao V., additional, Better, Nathan, additional, Villines, Todd C., additional, Cerci, Rodrigo, additional, Shaw, Leslee J., additional, Choi, Andrew D., additional, Dorbala, Sharmila, additional, Karthikeyan, Ganesan, additional, Lu, Bin, additional, Sinitsyn, Valentin, additional, Ansheles, Alexey A., additional, Kudo, Takashi, additional, Bucciarelli-Ducci, Chiara, additional, Nørgaard, Bjarne Linde, additional, Maurovich-Horvat, Pál, additional, Campisi, Roxana, additional, Milan, Elisa, additional, Louw, Lizette, additional, Allam, Adel H., additional, Bhatia, Mona, additional, Sewanan, Lorenzo, additional, Malkovskiy, Eli, additional, Cohen, Yosef, additional, Randazzo, Michael, additional, Narula, Jagat, additional, Morozova, Olga, additional, Pascual, Thomas N.B., additional, Pynda, Yaroslav, additional, Dondi, Maurizio, additional, Paez, Diana, additional, Einstein, Andrew J., additional, Hinterleitner, Gerd, additional, Lu, Yao, additional, Xu, Zhuoran, additional, Hirschfeld, Cole B., additional, Erinne, Ikenna, additional, Shetty, Mrinali, additional, Choi, Andrew, additional, Lopez-Mattei, Juan, additional, Parwani, Purvi, additional, Goda, Artan, additional, Shirka, Ervina, additional, Bouyoucef, Salah, additional, Chelghoum, Lydia, additional, Mansouri, Farouk, additional, Medjahedi, Abdelkader, additional, Naili, Qais, additional, Ridouh, Mokhtar, additional, Alasia, Diego, additional, Alberghina, Lucia, additional, Aramayo, Natalia, additional, Buchara, Diego, additional, Busso, Franco Gabriel, additional, Bustos Rivadero, Jose Javier, additional, Camilletti, Jorge, additional, Campanelli, Hugo, additional, Castro, Ricardo Belisario, additional, Daicz, Mariana, additional, del Riego, Horacio, additional, Dragonetti, Laura, additional, Echazarreta, Diego, additional, Erriest, Juan, additional, Faccio, Fernando, additional, Facello, Adolfo, additional, Gallegos, Hugo, additional, Geronazzo, Ricardo, additional, Glait, Horacio, additional, Hasbani, Victor, additional, Jäger, Victor, additional, Lewkowicz, Julio Manuel, additional, Lotti, Jose, additional, Maciel, Neiva, additional, Masoli, Osvaldo, additional, Mastrovito, Edgardo, additional, Medus, Maria, additional, Merani, Maria Fernanda, additional, Molteni, Susana, additional, Montecinos, Marcos, additional, Parisi, Gustavo, additional, Sueldo, Claudio Pereyra, additional, Perez de Arenaza, Diego, additional, Quintana, Luis, additional, Radzinschi, Alejandro, additional, Redruello, Marcela, additional, Rodríguez, Marina, additional, Rojas, Horacio, additional, Acuña, Arturo Romero, additional, Schere, Daniel, additional, Traverso, Sonia, additional, Vazquez, Gustavo, additional, Zeffiro, Susana, additional, Sakanyan, Mari, additional, Beuzeville, Scott, additional, Boktor, Raef, additional, Crowley, Michael, additional, Downie, D'Arne, additional, Dwivedi, Girish, additional, Elison, Barry, additional, Farouque, Omar, additional, Jasper, Kim, additional, Joshi, Subodh, additional, Lee, Joseph, additional, Lee, Kenneth, additional, Lui, Elaine, additional, Mcconachie, Peter, additional, Meaker, Joanne, additional, Nandurkar, Dee, additional, Neill, Johanne, additional, O'Rourke, Edward, additional, O'Sullivan, Patricia, additional, Pandos, George, additional, Premaratne, Manuja, additional, Prior, David, additional, Rutherford, Natalie, additional, Saunders, Connor, additional, Taubman, Kim, additional, Tauro, Andrew, additional, Taylor, Andrew, additional, Theuerle, James, additional, Thomas, Paul, additional, Tow, Jonathan, additional, Upton, Anthony, additional, Vamadevan, Shankar, additional, Wayne, Victor, additional, Wegner, Eva Alina, additional, Wong, David, additional, Younger, John, additional, Beitzke, Dietrich, additional, Feuchtner, Gudrun, additional, Sommer, Oliver, additional, Weiss, Konrad, additional, Maroz-Vadalazhskaya, Natallia, additional, Tserakhau, Uladzimir, additional, Homans, Filip, additional, Van De Heyning, Caroline M., additional, Araujo, Raúl, additional, Soldat-Stankovic, Valentina, additional, Stankovic, Sinisa, additional, Almeida, Augusto, additional, Anselmi, Carlos, additional, Azevedo, Guilherme S.A., additional, Bittencourt, Marcio Sommer, additional, Pianta, Diego Bromfman, additional, Cabeda, Estevan, additional, Carreira, Lara, additional, Coelho, Igor, additional, de Amorim Fernandes, Fernando, additional, de Lorenzo, Andrea, additional, Delgado, Roberta, additional, Erthal, Fernanda, additional, Fernandes, Fabio, additional, Fernandes, Juliano, additional, Ferreira de Souza, Thiago, additional, Foppa, Murilo, additional, Matos Alves, Wilson Furlan, additional, Gontijo, Cibele, additional, Gottlieb, Ilan, additional, Grossman, Gabriel, additional, Albernaz Siqueira, Maria Helena, additional, Nomura, Cesar Higa, additional, Koga, Katia Hiromoto, additional, Lima, Ronaldo, additional, Lopes, Rafael, additional, Marçal Filho, Hugo Humberto, additional, Masiero, Paulo, additional, Mastrocola, Luiz, additional, Menezes de Siqueira, Maria Eduarda, additional, Mesquita, Claudio, additional, Naves, Danilo, additional, Penna, Filipe, additional, Pinto, Ibraim, additional, Rocha, Thércio, additional, Rocha, Juliana Leal, additional, Rodrigues, Alfredo, additional, Salioni, Leila, additional, Sanches, Adelina, additional, Santos, Marcelo, additional, Da Silva, Leonardo Sara, additional, Schvartzman, Paulo, additional, Matushita, Cristina Sebastião, additional, Senra, Tiago, additional, Silva, Marcelo, additional, Soares, Carlos Eduardo, additional, Spiro, Bernardo, additional, Suaide Silva, Carlos Eduardo, additional, Torres, Rafael, additional, Monte, Guilherme Urpia, additional, Vilela, Andrea, additional, Villa, Alexandre Volney, additional, Vitola, Joao, additional, Voss, Themissa, additional, Waltrick, Roberto, additional, Zapparoli, Marcello, additional, Naseer, Hamid, additional, Garcheva-Tsacheva, Marina, additional, Ouattara, Tiémégna Florence, additional, Thou, Sarameth, additional, Varoeun, Soley, additional, Abikhzer, Gad, additional, Beanlands, Rob, additional, Chetrit, Michael, additional, Dabreo, Dominique, additional, Dennie, Carole, additional, Friedrich, Matthias, additional, Hafez, Mohmmed Nassoh, additional, Hanneman, Kate, additional, Miller, Robert, additional, Oikonomou, Anastasia, additional, Roifman, Idan, additional, Small, Gary, additional, Tandon, Vikas, additional, Trivedi, Adwait, additional, White, James, additional, Zukotynski, Katherine, additional, Alay, Rita, additional, Concha, Carmen, additional, Massardo, Teresa, additional, Abad, Pedro, additional, Anzola, Kelly, additional, Arturo, Harold, additional, Benitez, Luis, additional, Cadena, Alberto, additional, Zamudio, Carlos Caicedo, additional, Calderón, Antonio, additional, Gutierrez Villamil, Claudia T., additional, Jaimes, Claudia, additional, Londono, Juan L., additional, Lopez, Nelson, additional, Merlano-Gaitan, Sonia, additional, Murgieitio-Cabrera, Ramon, additional, Valencia, Manuel, additional, Vergel, Damiana, additional, Santamaria, Alejandro Zuluaga, additional, Solis, Felix, additional, Batinic, Tonci, additional, Franceschi, Maja, additional, Paar, Maja Hrabak, additional, Prpic, Marina, additional, Felipe Batista, Cuba: Juan, additional, Cabrera, Lazaro Omar, additional, Peix, Amalia, additional, Peña, Yamilé, additional, Rochela Vázquez, Luis Manuel, additional, Ntalas, Ioannis, additional, Kaminek, Milan, additional, Kincl, Vladimir, additional, Lang, Otto, additional, Abdulla, Jawdat, additional, Bøttcher, Morten, additional, Busk, Martin, additional, Geisler, Uka, additional, Gormsen, Lars C., additional, Hansson, Nicolaj, additional, Hess, Søren, additional, Hove, Jens, additional, Jensen, Lars Thorbjoern, additional, Jensen, Magnus T., additional, Kragholm, Kristian Hay, additional, Nørgaard, Bjarne L., additional, Øvrehus, Kristian, additional, Rasmussen, Jan, additional, Rønnow Sand, Niels Peter, additional, Sondergaard, Hanne, additional, Zaremba, Tomas, additional, Speckter, Herwin, additional, Amores, Nelson, additional, Velez, Mayra Sanchez, additional, Alrahman, Taghreed Abd, additional, Elsamad, Sherif Abd, additional, Abdelfattah, Alia, additional, Allam, Adel, additional, Elkaffas, Sameh, additional, Hassan, Mona, additional, Hussein, Elshaymaa, additional, Ibrahim, Ahmed, additional, Kandeel, Ahmed, additional, Ali, Mohamed Mandour, additional, Shaaban, Mahmoud, additional, Flores, Camila, additional, Gómez Leiva, Verónica Vanesa, additional, Liiver, Anita, additional, Larikka, Martti, additional, Uusitalo, Valtteri, additional, Agostini, Denis, additional, Berger, Clothilde, additional, Dietz, Matthieu, additional, Hyafil, Fabien, additional, Ohana, Mickaël, additional, Prigent, Kevin, additional, Regaieg, Hamza, additional, Sarda-Mantel, Laure, additional, H-Ici, Darach O., additional, Ayetey, Harold, additional, Angelidis, George, additional, Fragkaki, Christina, additional, Fragkiadaki, Chrysoula, additional, Georgoulias, Panagiotis, additional, Koutelou, Maria, additional, Kyrozi, Elena, additional, Lama, Niki, additional, Prassopoulos, Vassilis, additional, Spartalis, Michael, additional, Zaglavara, Theodora, additional, Gonzalez, Carla, additional, Gutierrez, Goleat, additional, Maldonado, Alejandro, additional, Martinez, Yassine, additional, Kovács, Attila, additional, Szilveszter, Bálint, additional, Banthia, Nilesh, additional, Bhat, Vivek, additional, Choudhury, Partha, additional, Chowdekar, Vijay Sai, additional, Christopher, Johann, additional, Garg, Tushar, additional, Goyal, Naresh Kumar, additional, Gupta, Ripen Kumar, additional, Gupta, Abhishek, additional, Hephzibah, Julie, additional, Jain, Shashank, additional, Krupa, Jesu, additional, Kumar, Parveen, additional, Kumar, Sukriti, additional, Lalchandani, Arati, additional, Mishra, Animesh, additional, Mishra, Vivaswan Dutt, additional, Mohan, Parul, additional, Ozair, Ahmad, additional, Pandey, Shivani, additional, Parameswaran, Ramanathapuram, additional, Patel, Chetan, additional, Patel, Tapan, additional, Patel, Shivani, additional, Vimala, Leena Robinson, additional, Kumar Sarangi, Dr Pradosh, additional, Sengupta, Shantanu, additional, Sethi, Arvind, additional, Sharma, Amit, additional, Sharma, Awadhesh Kumar, additional, Sharma, Punit, additional, Shrigiriwar, Apurva, additional, Singh, Santosh, additional, Singh, Harpreet, additional, Sood, Ashwani, additional, Verma, Atul, additional, Vyas, Ajay, additional, Soeriadi, Erwin Affandi, additional, Bun, Edison, additional, Hutomo, Febby, additional, Syawaluddin, Hilman, additional, Yudistiro, Ryan, additional, Albadr, Amjed, additional, Assadi, Majid, additional, Emami, Farshad, additional, Emami-Ardekani, Alireza, additional, Farzanehfar, Saeed, additional, Jafari, Ramezan, additional, Manafi-Farid, Reyhaneh, additional, Tajik, Maryam, additional, Arnson, Yoav, additional, Fuchs, Shmuel, additional, Goldkorn, Ronen, additional, Kennedy, John, additional, Leitman, Marina, additional, Shalev, Aryeh, additional, Acampa, Wanda, additional, Albano, Domenico, additional, Alongi, Pierpaolo, additional, Arnone, Gaspare, additional, Assante, Roberta, additional, Baritussio, Anna, additional, Bauckneht, Matteo, additional, Bianco, Francesco, additional, Bonfiglioli, Rachele, additional, Bovenzi, Francesco, additional, Bruno, Isabella, additional, Bruno, Andrea, additional, Busnardo, Elena, additional, Califaretti, Elena, additional, Casoni, Roberta, additional, Censullo, Vittorio, additional, Chierichetti, Franca, additional, Chiocchi, Marcello, additional, Cittanti, Corrado, additional, Clemente, Alberto, additional, Cuocolo, Alberto, additional, De Rimini, Maria Luisa, additional, De Vincentis, Giuseppe, additional, Della Tommasina, Veronica, additional, Dellegrottaglie, Santo, additional, Erba, Paola Anna, additional, Evangelista, Laura, additional, Faggi, Lara, additional, Faragasso, Evelina, additional, Florimonte, Luigia, additional, Frantellizzi, Viviana, additional, Gatti, Marco, additional, Gaudiano, Angela, additional, Gelardi, Fabrizia, additional, Gerali, Alberto, additional, Gimelli, Alessia, additional, Guglielmo, Marco, additional, Leccisotti, Lucia, additional, Liga, Riccardo, additional, Liguori, Carlo, additional, Longo, Giampiero, additional, Maffione, Margherita, additional, Marcassa, Claudio, additional, Matassa, Giovanni, additional, Mele, Donato, additional, Mircoli, Luca, additional, Paccagnella, Andrea, additional, Pacella, Sara, additional, Padovano, Federica, additional, Pellegrini, Dario, additional, Pergola, Valeria, additional, Pugliese, Luca, additional, Quartuccio, Natale, additional, Rampin, Lucia, additional, Ricci, Fabrizio, additional, Rubini, Giuseppe, additional, Russo, Vincenzo, additional, Sambuceti, Gianmario, additional, Scatteia, Alessandra, additional, Sciagrà, Roberto, additional, Spidalieri, Gianluca, additional, Stefanelli, Antonella, additional, Tedeschi, Carlo, additional, Ventroni, Guido, additional, Baugh, Dainia, additional, Madu, Ernest, additional, Aikawa, Tadao, additional, Asano, Hiroshi, additional, Fujimoto, Shinichiro, additional, Fujise, Koichiro, additional, Fukushima, Yoshimitsu, additional, Fukuyama, Kae, additional, Ichikawa, Yasutaka, additional, Ideguchi, Reiko, additional, Iguchi, Nobuo, additional, Imai, Masamichi, additional, Ishimura, Hayato, additional, Isobe, Satoshi, additional, Ito, Kimiteru, additional, Izawa, Yu, additional, Kadokami, Toshiaki, additional, Kasai, Tokuo, additional, Kato, Takao, additional, Kawamoto, Takashi, additional, Kiryu, Shigeru, additional, Kumita, Shinichiro, additional, Manabe, Osamu, additional, Maruno, Hirotaka, additional, Matsumoto, Naoya, additional, Miyagawa, Masao, additional, Moroi, Masao, additional, Nagamachi, Shigeki, additional, Nakajima, Kenichi, additional, Nakazato, Ryo, additional, Nanasato, Mamoru, additional, Naya, Masanao, additional, Norikane, Takashi, additional, Ohta, Yasutoshi, additional, Otomi, Yoichi, additional, Otsuka, Hideki, additional, Oyama-Manabe, Noriko, additional, Saito, Masaki, additional, Sarai, Masayoshi, additional, Sato, Junichi, additional, Sato, Daisuke, additional, Shiraishi, Shinya, additional, Takanami, Kentaro, additional, Takehana, Kazuya, additional, Taniguchi, Yasuyo, additional, Teragawa, Hiroki, additional, Tomizawa, Nobuo, additional, Umeji, Kyoko, additional, Wakabayashi, Yasushi, additional, Yamada, Shinichiro, additional, Yamazaki, Shinya, additional, Yoneyama, Tatsuya, additional, Rawashdeh, Mohammad, additional, Dautov, Tairkhan, additional, Makhdomi, Khalid, additional, Abass, Mostafa, additional, Garashi, Masoud, additional, Siraj, Qaisar, additional, Kalnina, Marika, additional, Haidar, Mohamad, additional, Komiagiene, Renata, additional, Kviecinskiene, Giedre, additional, Vajauskas, Donatas, additional, Karim, Noor Khairiah A., additional, Doucoure, Mady, additional, Reichmuth, Luise, additional, Samuel, Anthony, additional, Dieng, Mohamed Lemine, additional, Naojee, Ambedhkar Shantaram, additional, Hernandez, Estrella Aguilera, additional, Alducin Tellez, Cesar Rene, additional, Alexánderson-Rosas, Erick, additional, Barragan, Erika, additional, Cabada, Manuel, additional, Calderón, Daniel, additional, Carvajal-Juarez, Isabel, additional, Esparza, José, additional, Gama-Moreno, Manlio Gerardo, additional, Quinto, Virginia Garcia, additional, Gonzalez, Nelsy Coromoto, additional, Herrera-Zarza, Mary Carmen, additional, Meave, Aloha, additional, Medina Verdugo, Jesus Gregorio, additional, Melendez, Gabriela, additional, Morales Murguia, Rafael Humberto, additional, Navarro Quiroz, Carlos Salvador, additional, Ornelas, Mario, additional, Preciado-Anaya, Andres, additional, Preciado-Gutiérrez, Oscar Ulises, additional, Puente, Adriana, additional, Salazar, Aristóteles Ramírez, additional, Rosales Uvera, Sandra Graciela, additional, Rosales-Uvera, Sandra, additional, Serna Macias, Jose Antonio, additional, Sierra-Galan, Lilia, additional, Sierra-Galan, Lilia M., additional, Tirado Alderete, Juan Carlos, additional, Vallejo, Enrique, additional, Faraggi, Marc, additional, Sereegotov, Erdenechimeg, additional, Ben Rais, Nouzha, additional, Alaoui, Nadia Ismaili, additional, Kyiphyu, Thiri, additional, Oo, Su Thet, additional, Win, Soe Myat, additional, Zar, Htin, additional, Ghimire, Ram, additional, Neupane, Madhu, additional, Glaudemans, Andor, additional, Slart, Riemer, additional, Verschure, Derk, additional, Allen, Berry, additional, Edmond, John, additional, Mckenzie, Clare, additional, Tie, Stuart, additional, Van Pelt, Niels, additional, Worthington, Kirsten, additional, Young, Calum, additional, Soli, Idrissa Adamou, additional, Kana, Shehu, additional, Onubogu, Uchenna, additional, Sani, Mahmoud, additional, Bråten, Anders Tjellaug, additional, Jørgensen, Arve, additional, Vassbotn, Hanne-Elin, additional, Al Dhuhli, Humoud, additional, Jawa, Zabah, additional, Tag, Naima, additional, Fatima, Shazia, additional, Imran, Muhammad Babar, additional, Younis, Muhammad Numair, additional, Saadullah, Mohammad, additional, Malo, Yariela Herrera, additional, Lenturut-Katal, Dora, additional, Castillo, Manuel, additional, Ortellado, José, additional, Akhter, Afroza, additional, Cader, F. Aaysha, additional, Hussain, Raihan, additional, Khan, Saidur Rahman, additional, Mandal, Tapati, additional, Nasreen, Faria, additional, An, Yunqiang, additional, Cao, Dianbo, additional, Gong, Lianggeng, additional, Hou, Yang, additional, Jia, Chongfu, additional, Li, Tao, additional, Li, Caiying, additional, Liu, Hui, additional, Liu, Wenya, additional, Liu, Jinkang, additional, Ng, Ming-Yen, additional, Shi, Heshui, additional, Tang, Chunxiang, additional, Wang, Ximing, additional, Wang, Zhaoqian, additional, Wang, Yining, additional, Wu, Jiang, additional, Yi, Yan, additional, Yuan, Li, additional, Zhang, Tong, additional, Zhang, Longjiang, additional, Chavez, Edith, additional, Cruz, Carlos, additional, Llontop, Christian, additional, Morales, Rosanna, additional, Abrihan, Paz, additional, Bustos-Barroso, Asela, additional, Duldulao-Ogbac, Michele, additional, Eduarte, Christopher, additional, Obaldo, Jerry, additional, Quinon, Alvin, additional, San Juan, Belinda, additional, San Juan, Carlo Joe, additional, Sauler-Gomez, Marie Rhiamar, additional, Uy, Mila, additional, Kostkiewicz, Magdalena, additional, Kunikowska, Jolanta, additional, Teresinska, Anna, additional, Urbanik, Tomasz, additional, Bettencourt, Nuno, additional, Fontes-Carvalho, Ricardo, additional, Gavina, Cristina, additional, Gonçalves, Lino, additional, Macedo, Filipe, additional, Moreno, Nuno, additional, Sousa, Carla, additional, Timoteo, Ana Teresa, additional, Vidigal, Maria João, additional, Al Heidous, Mahmoud, additional, Ramanathan, Subramaniyan, additional, Arnous, Samer, additional, Aytani, Said, additional, Byrne, Angela, additional, Gleeson, Tadhg, additional, Kerins, David, additional, O'Brien, Julie, additional, Bang, Ji-In, additional, Bom, Henry, additional, Cheon, Miju, additional, Cheon, Gi Jeong, additional, Cho, Sang-Geon, additional, Hong, Chae Moon, additional, Jeong, Yong Hyu, additional, Kang, Won Jun, additional, Kang, Yeon-Koo, additional, Kim, Ji-Young, additional, Oh, So Won, additional, So, Young, additional, Song, Ho-Chun, additional, Won, Kyoung Sook, additional, Yoo, Soo Woong, additional, Mitevska, Irena, additional, Vavlukis, Marija, additional, Salobir, Barbara Gužic, additional, Štalc, Monika, additional, Benedek, Theodora, additional, Pop, Marian, additional, Stan, Claudiu, additional, Ansheles, Alexey, additional, Dariy, Olga, additional, Gagarina, Nina, additional, Itskovich, Irina, additional, Karalkin, Anatoliy, additional, Kokov, Alexander, additional, Marina, Gulya, additional, Migunova, Ekaterina, additional, Pospelov, Viktor, additional, Ryzhkova, Daria, additional, Sayfullina, Guzaliya, additional, Sergienko, Vladimir, additional, Shurupova, Irina, additional, Vakhromeeva, Margarita, additional, Valiullina, Nailia, additional, Zavadovsky, Konstantin, additional, Zhuravlev, Kirill, additional, Abazid, Rami, additional, Al Garni, Turki, additional, Alasnag, Mirvat, additional, Aljizeeri, Ahmed, additional, Amer, Hamid, additional, Amro, Ahmad, additional, Hamdy, Hesham, additional, Smettei, Osama, additional, Saranovic, Dragana Sobic, additional, Vlajkovic, Marina, additional, Keng, Felix, additional, See, Jason, additional, Berecova, Zuzana, additional, Mistinova, Jana Polakova, additional, Evbuomwan, Osayande, additional, Govender, Nerisha, additional, Hack, Jonathan, additional, Hadebe, Bawinile, additional, Hlongwa, Khanyisile, additional, Kaplan, Mitchell, additional, Lakhi, Hoosen, additional, Milos, Katarina, additional, Modiselle, Moshe, additional, More, Stuart, additional, Muambadzi, Ntanganedzeni, additional, Scholtz, Leonie, additional, Barreiro-Perez, Manuel, additional, Blanco, Isabel, additional, Broncano, Jordi, additional, Camarero, Alicia, additional, Casáns-Tormo, Irene, additional, De Haro, Javier, additional, Flotats, Albert, additional, García, Elia, additional, Mendiguchia, Ceferino Gutierrez, additional, Jimenez-Heffernan, Amelia, additional, Leta, Ruben, additional, Diaz, Javier Lopez, additional, Vega, Luis Lumbreras, additional, Manovel-Sánchez, Ana, additional, Monzonis, Amparo Martinez, additional, Patrut, Bianca, additional, Pubul, Virginia, additional, Perez, Ricardo Ruano, additional, Zeidan, Nahla, additional, Nanayakkara, Damayanthi, additional, Suliman, Ahmed, additional, Engblom, Henrik, additional, Murtadha, Mustafa, additional, Ostenfeld, Ellen, additional, Simonsson, Magnus, additional, Alkadhi, Hatem, additional, Buechel, Ronny Ralf, additional, Burger, Peter, additional, Gräni, Christoph, additional, Kamani, Christel, additional, Kawel-Böhm, Nadine, additional, Klaeser, Bernd, additional, Manka, Robert, additional, Prior, John, additional, Kaewchur, Tawika, additional, Khiewvan, Benjapa, additional, Kositwattanarerk, Arpakorn, additional, Namwongprom, Sirianong, additional, Thientunyakit, Tanyaluck, additional, Sayman, Haluk Burcak, additional, Yüksel, Mahmut, additional, Sebikali, Mugisha Julius, additional, Okello, Emmy, additional, Korol, Pavlo, additional, Noverko, Iryna, additional, Satyr, Maryna, additional, Ahmad, Tahir, additional, Alfakih, Khaled, additional, Andrade, Ivo, additional, Buckingham, Susan, additional, Bularga, Anda, additional, Carpenter, John-Paul, additional, Cole, Graham, additional, Cusack, David, additional, David, Sarojini, additional, Davis, Patrick, additional, Fairbairn, Timothy, additional, Ghosh, Arjun, additional, Ramkumar, Prasad Guntur, additional, Hamilton, Mark, additional, Haque, Faisal, additional, Hudson, Benjamin, additional, Johnstone, Annette, additional, Karthikeyan, V.J., additional, Kay, Mike, additional, Khan, Mohammad Ali, additional, Kitt, Jamie, additional, Low, Chen Sheng, additional, Mcalindon, Elisa, additional, Mccreavy, David, additional, Morrissey, Brian, additional, Motwani, Manish, additional, Na, Dilip, additional, Nicol, Edward, additional, Patel, Dilip, additional, Rodrigues, Jonathan, additional, Rofe, Chris, additional, Schofield, Rebecca, additional, Semple, Thomas, additional, Sheikh, Azeem, additional, Sinha, Apurva, additional, Subedi, Deepak, additional, Topping, William, additional, Tweed, Katherine, additional, Underwood, Stephen Richard, additional, Weir-Mccall, Jonathan, additional, Zuhairy, Hamed, additional, Abbasi, Taimur, additional, Abohashem, Shady, additional, Abramson, Sandra, additional, Al-Mallah, Mouaz, additional, Kumar, Mohan Ashok, additional, Balmer-Swain, Mallory, additional, Berman, Daniel, additional, Bernheim, Adam, additional, Bhatti, Sabha, additional, Biederman, Robert, additional, Bieging, Erik, additional, Bingham, Scott, additional, Bloom, Stephen, additional, Blue, Sean, additional, Borges, Andressa, additional, Branch, Kelley, additional, Bravo, Paco, additional, Buddhe, Sujatha, additional, Budoff, Matthew, additional, Bullock-Palmer, Renée, additional, Cahill, Michael, additional, Candela, Candace, additional, Cao, Jane, additional, Chatterjee, Saurav, additional, Chatzizisis, Yiannis, additional, Chaudhuri, Nita Ray, additional, Cheezum, Michael, additional, Chelliah, Anjali, additional, Chen, Tiffany, additional, Chen, Marcus, additional, Chen, Lu, additional, Chokshi, Aalap, additional, Chung, Jina, additional, Danciu, Sorin, additional, DeSisto, William, additional, Dilorenzo, Michael, additional, Doukky, Rami, additional, Duvall, William, additional, Ferencik, Maros, additional, Foster, Cameron, additional, Fuisz, Anthon, additional, Gannon, Michael, additional, German, David, additional, Gerson, Myron, additional, Geske, Jeffrey, additional, Hage, Fadi, additional, Haider, Agha, additional, Haider, Sofia, additional, Hamirani, Yasmin, additional, Hassen, Karen, additional, Hendel, Robert, additional, Henkel, Jacqueline, additional, Horgan, Stephen, additional, Hyun, Mark, additional, Janardhanan, Rajesh, additional, Jerome, Scott, additional, Kalra, Dinesh, additional, Kassop, David, additional, Kinkhabwala, Mona, additional, Kinzfogl, George, additional, Koch, Bernard, additional, Koweek, Lynne, additional, Krepp, Joseph, additional, Kwon, Younghoon, additional, Layer, Jay, additional, Lesser, John, additional, Leung, Steve, additional, Lisske, Bernadette, additional, Magurany, Kathleen, additional, Markowitz, Jeremy, additional, Mccullough, Brenda, additional, Moalemi, Azita, additional, Moffitt, Chanan, additional, Montanez, Juan, additional, Moore, Warren, additional, Morayati, Shamil, additional, Mossa-Basha, Mahmud, additional, Mrsic, Zorana, additional, Murthy, Venkatesh, additional, Nagpal, Prashant, additional, Nelson, Katarina, additional, Nijjar, Prabhjot, additional, O’Quinn, Rupal, additional, Passen, Edward, additional, Patel, Toral, additional, Patil, Pravin, additional, Pursnani, Amit, additional, Quachang, Nancy, additional, Rabbat, Mark, additional, Ranjan, Pragya, additional, Lozano, Patricia Rodriguez, additional, Schemmer, Mary, additional, Seifried, Rebecca, additional, Shah, Nishant, additional, Shah, Amee, additional, Shanbhag, Sujata, additional, Sharma, Gaurav, additional, Skotnicki, Robert, additional, Sobczak, Michael, additional, Soman, Prem, additional, Sorrell, Vincent, additional, Srichai, Monvadi, additional, Streeter, Jim, additional, Strickland, Leah, additional, Suliman, Suliman, additional, Tebyanian, Naghmeh, additional, Thomas, Dustin, additional, Thompson, Randall, additional, Uretsky, Seth, additional, Vallurupalli, Srikanth, additional, Vandyck-Acquah, Marian, additional, Verma, Vikas, additional, Villines, Todd, additional, Weinstein, Joseph, additional, Wolinsky, David, additional, Zareba, Karolina, additional, Zgaljardic, Michael, additional, Beretta, Mario, additional, Ferrando, Rodolfo, additional, Kapitan, Miguel, additional, Mut, Fernando, additional, Djuraev, Omoa, additional, Rozikhodjaeva, Gulnora, additional, Vera, Luisa, additional, Duc, Binh Duong, additional, Nguyen, Xuan Canh, additional, and Hiep Nguyen, Phuoc Minh, additional
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- 2022
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43. Statistical Analysis Plan: Clarithromycin and the Risk of incident Atrial Fibrillation -a secondary analysis of the CLARICOR (clarithromycin for patients with stable coronary heart disease) trial
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Jensen, Gorm Boje, Winkel, Per, Jensen, Magnus T, Jakobsen, Janus Christian, Hilden, J��rgen, Olsen, Markus Harboe, Lindschou, Jane, and Gluud, Christian
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Introduction Atrial fibrillation (AF) is the most common cardiac arrhythmia, and AF is a major contributor to cardiovascular mortality and morbidity. The CLARICOR randomised trial of clarithromycin compared with placebo in patients with stable coronary heart disease trial, found increased all-cause and cardiovascular mortality of the brief clarithromycin regimen. Here, we outline an analysis of the relationship between use of clarithromycin and incident AF in the CLARICOR trial. Methods The CLARICOR trial randomised 4372 patients with stable coronary artery disease in Copenhagen during October 1999 to April 2000. Outcomes were assessed through validated Danish registers. The outcome of interest is incident AF assessed through Danish national registers. Using Cox proportional hazard method, we will determine the effect of clarithromycin on incidence of AF. The analyses will be adjusted for protocol specified stratification variables. Analyses both including and excluding participants with AF occurring before randomisation will be performed. Conclusion This study will potentially contribute to the understanding of development of AF, relative to use of clarithromycin in such patients.
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- 2022
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44. Diagnostic and prognostic value of the electrocardiogram in stable outpatients with type 2 diabetes
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Gregers, Mads C T, Schou, Morten, Jensen, Magnus T, Jensen, Jesper, Petrie, Mark C, Vilsbøll, Tina, Goetze, Jens Peter, Rossing, Peter, Jørgensen, Peter G., Gregers, Mads C T, Schou, Morten, Jensen, Magnus T, Jensen, Jesper, Petrie, Mark C, Vilsbøll, Tina, Goetze, Jens Peter, Rossing, Peter, and Jørgensen, Peter G.
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Aims . The European Society of Cardiology guidelines on diabetes and cardiovascular disease (CVD) recommend an electrocardiogram (ECG) in patients with diabetes and hypertension or with suspected CVD. We investigated whether ECG abnormalities can be used as a diagnostic and prognostic marker of heart failure (HF) in patients with type-2 diabetes (T2D) in secondary care diabetes-clinics. Methods . We included 722 patients with T2D in sinus rhythm. HF with preserved ejection fraction (HFpEF) was defined according to the European Society of Cardiology guidelines. Heart failure with mid-range ejection fraction (HFmrEF) was patients with dyspnoea and an LVEF 41-49%. Heart failure with reduced ejection fraction (HFrEF) or asymptomatic left ventricular systolic dysfunction (ALVSD) was defined as a LVEF ≤40%. Results . Overall, 24% patients had ECG abnormalities. A total of 15% had HF whereof 48% had ECG abnormalities. A normal ECG had a 99.3% negative predictive value (NPV) of ruling out HFrEF/ALVSD. In a sub-group with 0-1 simple clinical risk markers, the ECG ruled out both HFrEF/ALVSD, HFmrEF, and HFpEF with an NPV of 96.6%. The hazard-ratio (HR) of incident CVD or death in patients with HF and a normal ECG compared with patients without HF was 1.85 [95%CI 1.01-3.39], p = .05, while an abnormal ECG increased the HR to 3.84 [2.33-6.33], p < .001. Conclusion . HFrEF/ALVSD and HFmrEF were rare and HFpEF was frequent in this T2D population. A normal ECG ruled out HFrEF/ALVSD and in a sub-population with 0-1 simple clinical risk markers also both HFrEF/ALVSD, HFmrEF, and HFpEF.Key messages What is already known about this subject?In early studies of unselected patients from primary care with suspected chronic heart failure, the presence of a normal ECG was found be useful to rule out heart failure with reduced ejection fraction. What does this study add?This study confirms that a standard electrocardiogram when normal in 722 stable outpatients with type 2 diabetes c
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- 2022
45. Potential role of conventional and speckle-tracking echocardiography in the screening of structural and functional cardiac abnormalities in elderly individuals:Baseline echocardiographic findings from the LOOP study
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Olsen, Flemming Javier, Diederichsen, Søren Zöga, Jørgensen, Peter Godsk, Jensen, Magnus T., Dahl, Anders, Landler, Nino Emmanuel, Graff, Claus, Brandes, Axel, Krieger, Derk, Haugan, Ketil, Køber, Lars, Højberg, Søren, Svendsen, Jesper Hastrup, Biering-Sørensen, Tor, Olsen, Flemming Javier, Diederichsen, Søren Zöga, Jørgensen, Peter Godsk, Jensen, Magnus T., Dahl, Anders, Landler, Nino Emmanuel, Graff, Claus, Brandes, Axel, Krieger, Derk, Haugan, Ketil, Køber, Lars, Højberg, Søren, Svendsen, Jesper Hastrup, and Biering-Sørensen, Tor
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Background Elderly individuals occupy an increasing part of the general population. Conventional and speckle-tracking transthoracic echocardiography may help guide risk stratification in these individuals. The purpose of this study was to evaluate the potential utility of conventional and speckle-tracking echocardiography in the screening of cardiac abnormalities in the elderly population. Methods Two cohorts of elderly individuals (sample size: 1441 and 944) were analyzed, who were part of a randomized controlled clinical trial (LOOP study) and of an observational study (Copenhagen City Heart Study), recruiting participants from the general population >70 years of age with cardiovascular risk factors (arterial hypertension, diabetes mellitus, heart failure, or prior stroke) and sinus rhythm. Participants underwent a comprehensive transthoracic echocardiographic examination, including myocardial speckle tracking. Cardiac abnormalities were defined according to the ASE/EACVI guidelines. Results Structural cardiac abnormalities such as left ventricular (LV) remodeling, mitral annular calcification (MAC), and aortic valve sclerosis (with or without stenosis) were highly prevalent in the LOOP study (40%, 39%, and 27%, respectively). Moreover, a high prevalence of functional cardiac alterations such as LV diastolic dysfunction (LVDD), abnormal LV longitudinal systolic strain (GLS), and abnormal left atrial (LA) reservoir strain was present in the LOOP study (27%, 18%, and 9%, respectively). Likewise, the rate of LVDD, abnormal GLS, and abnormal LA reservoir strain was comparable in the validation sample from the Copenhagen City Heart Study. In line with these findings, subjects with LV remodeling, MAC, and aortic valve changes had a higher prevalence of LVDD, abnormal GLS, and abnormal LA reservoir strain than those without structural cardiac alterations. Conclusion The findings of this study highlight the potential clinical utility of conventional and speckle-trac
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- 2022
46. Frailty in cardiology: definition, assessment and clinical implications for general cardiology. A consensus document of the Council for Cardiology Practice (CCP), Association for Acute Cardio Vascular Care (ACVC), Association of Cardiovascular Nursing and Allied Professions (ACNAP), European Association of Preventive Cardiology (EAPC), European Heart Rhythm Association (EHRA), Council on Valvular Heart Diseases (VHD), Council on Hypertension (CHT), Council of Cardio-Oncology (CCO), Working Group (WG) Aorta and Peripheral Vascular Diseases, WG e-Cardiology, WG Thrombosis, of the European Society of Cardiology, European Primary Care Cardiology Society (EPCCS)
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Richter, Dimitri, Guasti, Luigina, Walker, David, Lambrinou, Ekaterini, Lionis, Christos, Abreu, Ana, Savelieva, Irina, Fumagalli, Stefano, Bo, Mario, Rocca, Bianca, Jensen, Magnus T, Pierard, Luc, Sudano, Isabella, Aboyans, Victor, Asteggiano, Riccardo, Richter, Dimitri, Guasti, Luigina, Walker, David, Lambrinou, Ekaterini, Lionis, Christos, Abreu, Ana, Savelieva, Irina, Fumagalli, Stefano, Bo, Mario, Rocca, Bianca, Jensen, Magnus T, Pierard, Luc, Sudano, Isabella, Aboyans, Victor, and Asteggiano, Riccardo
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Frailty is a health condition leading to many adverse clinical outcomes. The relationship between frailty and advanced age, multimorbidity and disability has a significant impact on healthcare systems. Frailty increases cardiovascular (CV) morbidity and mortality both in patients with or without known CV disease. Though the recognition of this additional risk factor has become increasingly clinically relevant in CV diseases, uncertainty remains about operative definitions, screening, assessment, and management of frailty. Since the burdens of frailty components and domains may vary in the various CV diseases and clinical settings, the relevance of specific frailty-related aspects may be different. Understanding these issues may allow general cardiologists a clearer focus on frailty in CV diseases and thereby make more tailored clinical decisions and therapeutic choices in outpatients. Guidance on identification and management of frailty are sparse and an international consensus document on frailty in general cardiology is lacking. Moreover, new options linked with eHealth are going to better define and manage frailty. This consensus document on definition, assessment, clinical implications, and management of frailty provides an input to integrate strategies pre- and post-acute CV events with a comprehensive view including out of hospital, office-based diagnostic and therapeutic choices, and based on a multidisciplinary team approach (general cardiologists, nurses, and general practitioners).
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- 2022
47. Elevated resting heart rate is associated with greater risk of cardiovascular and all-cause mortality in current and former smokers
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Jensen, Magnus T., Marott, Jacob L., and Jensen, Gorm B.
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- 2011
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48. Additional file 1 of The novel inflammatory biomarker GlycA and triglyceride-rich lipoproteins are associated with the presence of subclinical myocardial dysfunction in subjects with type 1 diabetes mellitus
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Puig-Jové, Carlos, Julve, Josep, Castelblanco, Esmeralda, Julián, M Teresa, Amigó, Núria, Andersen, Henrik U, Ahluwalia, Tarunveer S, Rossing, Peter, Mauricio, Dídac, Jensen, Magnus T, and Alonso, Núria
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Supplementary Material 1: Supplementary Fig. 1: Comparison of the distribution of the predicted probabilities showing the classification performance of the presence of MCD between two different models, being the x-axis the predicted probabilities for both classes and the y-axis the count of observations. A: Model 1 includes classical risk variables (age, sex, eGFR, NTproBNP, BMI, diabetes duration and systolic blood pressure >140mmHg). B: Model 2 includes classical risk variables and the NMR-assessed biomarkers. The inclusion of NMR parameters significantly increased the AUROC from 0.62 [0.56–0.68] to 0.67 [0.61–0.73], with a NRI considering NMR-assessed parameters of 21%. MCD: myocardial dysfunction, BMI: body mass index, NMR: nuclear magnetic resonance, AUROC: area under the ROC curve, NRI: net reclassification improvement.
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- 2022
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49. Prevalence of systolic and diastolic dysfunction in patients with type 1 diabetes without known heart disease: the Thousand & 1 Study
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Jensen, Magnus T., Sogaard, Peter, Andersen, Henrik U., Bech, Jan, Hansen, Thomas F., Galatius, Søren, Jørgensen, Peter G., Biering-Sørensen, Tor, Møgelvang, Rasmus, Rossing, Peter, and Jensen, Jan S.
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- 2014
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50. Ranking of psychosocial and traditional risk factors by importance for coronary heart disease: the Copenhagen City Heart Study
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Schnohr, Peter, Marott, Jacob L., Kristensen, Tage S., Gyntelberg, Finn, Grønbæk, Morten, Lange, Peter, Jensen, Magnus T., Jensen, Gorm B., and Prescott, Eva
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- 2015
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