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Additional file 1 of The novel inflammatory biomarker GlycA and triglyceride-rich lipoproteins are associated with the presence of subclinical myocardial dysfunction in subjects with type 1 diabetes mellitus

Authors :
Puig-Jové, Carlos
Julve, Josep
Castelblanco, Esmeralda
Julián, M Teresa
Amigó, Núria
Andersen, Henrik U
Ahluwalia, Tarunveer S
Rossing, Peter
Mauricio, Dídac
Jensen, Magnus T
Alonso, Núria
Publication Year :
2022
Publisher :
figshare, 2022.

Abstract

Supplementary Material 1: Supplementary Fig. 1: Comparison of the distribution of the predicted probabilities showing the classification performance of the presence of MCD between two different models, being the x-axis the predicted probabilities for both classes and the y-axis the count of observations. A: Model 1 includes classical risk variables (age, sex, eGFR, NTproBNP, BMI, diabetes duration and systolic blood pressure >140mmHg). B: Model 2 includes classical risk variables and the NMR-assessed biomarkers. The inclusion of NMR parameters significantly increased the AUROC from 0.62 [0.56–0.68] to 0.67 [0.61–0.73], with a NRI considering NMR-assessed parameters of 21%. MCD: myocardial dysfunction, BMI: body mass index, NMR: nuclear magnetic resonance, AUROC: area under the ROC curve, NRI: net reclassification improvement.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....390bc21c6d04a0f0e9db288dc9b78379
Full Text :
https://doi.org/10.6084/m9.figshare.21628735