9 results on '"Jean-Marie Léger"'
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2. Family, Alzheimer's disease and negative symptoms
- Author
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Jean Marie Léger, Jean Pierre Clément, Cyril Hazif-Thomas, Philippe Thomas, CHRU de Poitiers - La Miletrie (Poitiers), and CH Esquirol [Limoges] ( CH Esquirol )
- Subjects
medicine.medical_specialty ,Psychometrics ,[ SCCO.PSYC ] Cognitive science/Psychology ,Cognition ,Disease ,medicine.disease ,Psychiatry and Mental health ,Distress ,medicine ,Dementia ,Apathy ,[ SCCO ] Cognitive science ,Geriatrics and Gerontology ,medicine.symptom ,Alzheimer's disease ,Psychiatry ,Psychology ,Depression (differential diagnoses) - Abstract
Background The aim of this study is to look at the correlation between the presence of apathy measured by Marin's scale and family complaints related to withdrawal and the loss of motivation, or depression. The multicentre study was performed on 58 non-demented elderly people, 132 outpatients with Alzheimer's-type dementia, as well as their main caregiver. Methods After agreement of the patients and the family, the patients were assessed using different scales: Cornell's for depression, Marin's for apathy, MMS for cognitive disorders, and IRG for dependence. At the same time, two self-administered questionnaires were given to the patients' families: one concerning a list of complaints scored from 1 to 4 relating to various disorders and the other addressing the boundary ambiguities translated from Boss' questionnaire. The 58 non-demented people were 81.20 years old±13.75. One hundred and thirty-two demented patients were included: 39 men and 93 women. The mean age was 79.47 years±9.03. Results The first family complaint relates to the loss of motivation (65%). Apathy and depression occur more frequently in dementia, in particular when the MMS is degraded. Depression and apathy attracted a high complaint score. In our study the score of boundary ambiguity is higher among patients with a weak cognitive status. A high level of ambiguity is accompanied by a high score of family complaints. When the family complaint concerning the loss of motivation is present, apathy is significantly more common. Family complaints about withdrawal and loss of motivation are frequently present, and are congruent with the actual presence of apathy in the patient. It bears witness to the distress felt by families faced with the loss of ability noted in the demented person. The family's difficulties are increased by the patient's depression. Copyright © 2001 John Wiley & Sons, Ltd.
- Published
- 2001
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3. Secteur psychiatrique et personnes âgées
- Author
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Jean-Marie Léger
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Geriatrics ,medicine.medical_specialty ,Health (social science) ,business.industry ,Public health ,Salud mental ,Senile dementia ,medicine.disease ,Mental health ,Central nervous system disease ,Degenerative disease ,medicine ,Geriatrics and Gerontology ,Psychiatry ,business ,Gerontology - Published
- 1995
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4. [Prognosis of depression in the elderly]
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Jean-Marie, Léger
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Depressive Disorder ,Comorbidity ,Prognosis ,Psychophysiologic Disorders ,Survival Rate ,Suicide ,Recurrence ,Risk Factors ,Cause of Death ,Chronic Disease ,Humans ,France ,Treatment Failure ,Aged - Abstract
The prognosis of depression, when the depression is diagnosed, is rather similar in the elderly and in younger adults. Recovery, after the initial episode or after one relapse or recurrence, is observed in about two thirds of the patients. However, depression increases the vulnerability of the elderly and is associated with an elevation of mortality, mainly due to the occurrence of somatic pathologies, which could be facilitated by the depression. Relapses, recurrences, chronicity and absence of therapeutic response are associated with inadequate treatment or follow-up. The prognosis of depression in elderly people requires a systematic diagnostic research and an appropriate treatment. The importance of follow-up and of a psychotherapeutic approach associated with antidepressant drugs should be emphasized.
- Published
- 2005
5. Dépistage précoce de la démence : annonce du diagnostic et dimensions éthiques
- Author
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Jean-Gabriel Ouango and Jean-Marie Léger
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Health (social science) ,Geriatrics and Gerontology ,Gerontology - Abstract
Les demences degeneratives (principalement la maladie d’Alzheimer) sont depuis quelques annees les cibles de recherches bio-medicales, anatomocliniques et instrumentales dont certaines sont resolument orientees vers la decouverte d’un ou de plusieurs marqueurs pathologiques precoces. L’evolution progressivement aggravee de ces maladies du sujet âge, le nombre de plus en plus croissant de personnes de plus de 65 ans, l’espoir de decouverte de medicaments efficaces et les possibilites d’aides medicosociales justifient tous ces efforts. Mais les resultats fournis par la recherche (anatomique, genetique, biologique, clinique, neuropsychologique et radiologique) ne permettent pas encore un diagnostic de certitude en debut de la maladie. C’est pourquoi l’annonce du diagnostic a un stade precoce pose encore des problemes ethiques importants dans la mesure ou l’avis du patient n’est pas souvent pris en compte dans les decisions du therapeute et de la famille. Cette annonce devrait donc obeir a des regles de prudence pour l’interet de la personne malade.
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- 2001
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6. [Diogenes syndrome and Hoarding disorder: Same or different?]
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Lavigne B, Hamdan M, Faure B, Merveille H, Pareaud M, Tallon E, Bouthier A, Clément JP, and Calvet B
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- Anxiety Disorders classification, Diagnosis, Differential, Hoarding Disorder classification, Humans, Psychiatric Status Rating Scales, Syndrome, Anxiety Disorders psychology, Hoarding Disorder psychology
- Abstract
Introduction: In 2013, the American Psychiatric Association published the DSM-5. In this new version, new diagnoses were proposed including the Hoarding disorder. In the French semeiology, the Diogenes syndrome is described, among other symptoms, by a pathological tendency to accumulate objects called syllogomania which is very close to hoarding. This paper explores the similarities and differences between the two syndromes., Description: The Diogenes syndrome was first described in 1966 but was officially named for the ancient Greek philosopher in 1975 by Clark. Its frequency is around five for 100,000 persons. Many aetiologies have been known to be associated with the Diogenes syndrome: schizophrenia, dementia - especially frontotemporal type, anxiety disorders, mood disorders, and substance abuse - especially alcohol abuse. The diagnostic requires one major criterion, the inability to ask for medical or social help, and one of three minor criteria: a pathological relationship to the body, which leads to somatic illness; a pathological relationship to the society, which leads to a progressive exclusion from it; and finally, a pathological link with objects. This last criterion is very interesting because it is closely related to the Hoarding syndrome: indeed, patients with syllogamania, as also named, have a tendency to hoard every object they find. At the end, their homes are full of useless objects, and some living places can be unusable because they are cluttered and congested. This last point is similar to the definition given in the DSM-5 for the Hoarding disorder which describes a persistent difficulty parting with possessions; distress associated with discarding possessions; and accumulations that congest and clutter active living areas. The Hoarding disorder was first part of the Obsessive and compulsive disorders, but it has progressively appeared that it could be individualized with its own prevalence of 2.3% to 14% lifetime. Genetical studies have shown that at least 50% of patients suffering from excessive hoarding had a relative with a dimension of hoarding. Finally, Mattaix-Cols et al. decided to create a new syndrome in the DSM-5, and the Hoarding disorder was born., Discussion: The discussion begins with relationships between the Hoarding disorder and the Diogenes syndrome. A patient with hoarding, and a poor insight, could be very isolated, and could persist in a lack of calling for help, because of not being aware of his pathology. Thus, it could be diagnosed as a Hoarding syndrome with a poor insight, or as a Diogenes syndrome, with the first major criterion (lack of calling for help) and one of the three minor criteria, the syllogomania, or hoarding. Moreover, some authors have described old people living for many years with a tendency to hoard. Progressively, some of them had a congested and cluttered home, and a few were living in squalor, a description very close to the Diogenes syndrome. Finally, we discuss the comorbidity of Hoarding disorder and Diogenes syndrome. In particular, the first one is associated with Attention deficit and hyperactivity disorders; and some authors also described the links between ADHD, bipolar disorder and frontotemporal dementia which is one of the aetiologies of the Diogenes syndrome. A psychodynamic model in which ADHD, Hoarding disorder and Diogenes syndrome are linked can be imagined, and the last one could be an overlooked evolution of the two first syndromes., Conclusion: In conclusion, we can imagine a dimensional model, based on two dimensions: hoarding and squalor. Hoarding disorder is the major expression of the first dimension, and Diogenes syndrome the major expression of the second. Both of them could be a different expression of one central aetiology. More studies are needed to complete this vision., (Copyright © 2016 L'Encéphale, Paris. Published by Elsevier Masson SAS. All rights reserved.)
- Published
- 2016
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7. [Negative hallucination, self-consciousness and ageing].
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Hazif-Thomas C, Stephan F, Walter M, and Thomas P
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- Anxiety Disorders diagnosis, Anxiety Disorders therapy, Delusions diagnosis, Delusions therapy, Denial, Psychological, Depressive Disorder diagnosis, Depressive Disorder therapy, Electroconvulsive Therapy, Hallucinations diagnosis, Hallucinations therapy, Humans, Psychotic Disorders diagnosis, Psychotic Disorders therapy, Reality Testing, Stress, Psychological diagnosis, Stress, Psychological psychology, Stress, Psychological therapy, Transcranial Magnetic Stimulation, Aging psychology, Anxiety Disorders psychology, Delusions psychology, Depressive Disorder psychology, Hallucinations psychology, Psychotic Disorders psychology, Self Concept
- Abstract
Background: Negative hallucinations are characterized by a defect in perception of an object or a person, or a denial of the existence of their perception. Negative hallucinations create blank spaces, due to both an impossible representation and an incapability of investment in reality. They have a close relationship with Cotard's syndrome, delusional theme of organ denial observed in melancholic syndromes in the elderly., Methods: Phenomenological approach. The phenomenology of negative hallucinations provides quite an amount of information on the origin of the psychotic symptoms when one is rather old., Results: The connections between hallucinations, mood disorders and negative symptoms are often difficult to live with for the nearest and dearest. Negative hallucinations require a strict approach to identify their expression that is crucial because a wide heterogeneity exists within the pathological pictures, as in Cotard's syndrome. Although the negative hallucination has an anti traumatic function in elderly people fighting against mental pain, it still represents a deficiency in symbolization. The prevalence of this symptom is without doubt underestimated, although its presence often underlines thymic suffering that is more striking. These hallucinatory symptoms have an important impact on the patients' daily life, and they appear to be prisoners of a suffering, which cannot be revealed., Conclusions: We propose in this article to review the clinical symptoms of negative hallucinations in the elderly and the way to manage them. The medicinal approaches are not always effective. A greater place must be given to what is in connection with the body, aiming at a strong impact and thus to offer non-pharmacological approaches, such as somatic ones, which can be either invasive (electroconvulsive therapy) or not (transcranial magnetic stimulation)., (Copyright © 2014. Published by Elsevier Masson SAS.)
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- 2015
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8. [About a very late-onset obsessive-compulsive disorder].
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Hamdan M, Lavigne B, Chandon G, Calvet B, and Clement JP
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- Age Factors, Aged, Anxiety Disorders diagnosis, Anxiety Disorders psychology, Anxiety Disorders therapy, Cognitive Behavioral Therapy, Combined Modality Therapy, Diagnosis, Differential, Dopamine Agents adverse effects, Dopamine Agents therapeutic use, Family Conflict psychology, Female, Humans, Obsessive-Compulsive Disorder chemically induced, Obsessive-Compulsive Disorder psychology, Obsessive-Compulsive Disorder therapy, Parkinson Disease diagnosis, Parkinson Disease drug therapy, Parkinson Disease psychology, Psychotropic Drugs therapeutic use, Urinary Retention psychology, Obsessive-Compulsive Disorder diagnosis
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- 2014
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9. [Psychiatric disorders in non demented elderly people].
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Clément JP and Leger JM
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- Age Factors, Aged, Anxiety Disorders diagnosis, Anxiety Disorders therapy, Bipolar Disorder diagnosis, Bipolar Disorder therapy, Delirium diagnosis, Delirium therapy, Depression diagnosis, Depression therapy, Diagnosis, Differential, Humans, Hysteria diagnosis, Hysteria therapy, Psychopathology, Risk Factors, Socioeconomic Factors, Geriatric Psychiatry trends, Mental Disorders diagnosis, Mental Disorders therapy
- Abstract
Psychogeriatrics is a rapidly growing field. In France, the focus is currently on targeted education and specific management. Psychiatric disorders may be atypical in the elderly, and may also be difficult to distinguish from the effects of aging or somatic disorders. The principal disorders observed in old age are depression, late delusion, anxiety disorder, hysteria, delirium and mania. Depression has specific features, depressive equivalents, particular risk factors, and a categorical and dimensional therapeutic approach. Diagnosis and screening must be improved Late delusion is organized around a notion of injury, and is an active attempt to deal with isolation, depression and anxiety. The term "very late-onset schizophrenia-like psychosis" has been proposed. Anxiety also has specific features in the elderly and is intimately related to depression. If left untreated, the consequences can be severe. Hysteria is pathoplastic with time, age and educational status. Pseudocognitive conversions are starting to be seen in old age. Delirium is very frequent in the elderly; it is often multifactorial, but psychosocial factors must not be underestimated. Mania can also be provoked by somatic disease, and mixed syndromes are far from rare. Dementia can be approached from its psychopathological dimension, particularly in terms of psychosocial risk factors and protective factors relating to the individual's biography and personality. Thus, psychogeriatrics is an integrated medical discipline in which psychiatric disorders are approached through specific clinical management, oriented research and structured training.
- Published
- 2006
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