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1. Cationic phosphonolipids as non viral vectors for DNA transfection

Author

Nathalie Le Bris, Gwénaëlle Le Bolc’h, Marie-Pierre Audrézet, Claude Férec, Jean-Jacque Yaouanc, Jean-Claude Climent, and Herve Des Abbayes

Subjects
Dna transfection, Biochemistry, Chemistry, Organic Chemistry, Drug Discovery, Cationic polymerization, Molecular biology, Mannich reaction, Viral vector
Abstract

The Mannich reaction from fatty phosphites followed by quaternarisation of the resulting aminophosphonates led to new cationic phosphonolipids which showed promising DNA transfection properties.

Published
1995
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