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Cationic phosphonolipids as non viral vectors for DNA transfection

Authors :
Nathalie Le Bris
Gwénaëlle Le Bolc’h
Marie-Pierre Audrézet
Claude Férec
Jean-Jacque Yaouanc
Jean-Claude Climent
Herve Des Abbayes
Source :
Tetrahedron Letters. 36:6681-6684
Publication Year :
1995
Publisher :
Elsevier BV, 1995.

Abstract

The Mannich reaction from fatty phosphites followed by quaternarisation of the resulting aminophosphonates led to new cationic phosphonolipids which showed promising DNA transfection properties.

Details

ISSN :
00404039
Volume :
36
Database :
OpenAIRE
Journal :
Tetrahedron Letters
Accession number :
edsair.doi...........cd726c3d391f67a44e0c8ebd5729ef04
Full Text :
https://doi.org/10.1016/00404-0399(50)1389-y