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1. Facile Synthesis of a Series of Non-Symmetric Thioethers Including a Benzothiazole Moiety and Their Use as Efficient In Vitro anti-Trypanosoma cruzi Agents

Author

Alcives Avila-Sorrosa, Jazz D. Tapia-Alvarado, Benjamín Nogueda-Torres, Karla Fabiola Chacón-Vargas, Francisco Díaz-Cedillo, María Elena Vargas-Díaz, and David Morales-Morales

Subjects
Trypanosoma cruzi, Chagas disease, benzothiazole derivatives, non-symmetric thioethers, neglected diseases, Organic chemistry, QD241-441
Abstract

A series of 2-benzylsulfanyl benzothiazole (BTA) derivatives were synthesized and fully characterized and in vitro tested against two strains of T. cruzi (NINOA and INC-5), exhibiting good activities at low concentrations.

Published
2019
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