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Facile Synthesis of a Series of Non-Symmetric Thioethers Including a Benzothiazole Moiety and Their Use as Efficient In Vitro anti-Trypanosoma cruzi Agents

Authors :
Alcives Avila-Sorrosa
Jazz D. Tapia-Alvarado
Benjamín Nogueda-Torres
Karla Fabiola Chacón-Vargas
Francisco Díaz-Cedillo
María Elena Vargas-Díaz
David Morales-Morales
Source :
Molecules, Vol 24, Iss 17, p 3077 (2019)
Publication Year :
2019
Publisher :
MDPI AG, 2019.

Abstract

A series of 2-benzylsulfanyl benzothiazole (BTA) derivatives were synthesized and fully characterized and in vitro tested against two strains of T. cruzi (NINOA and INC-5), exhibiting good activities at low concentrations.

Details

Language :
English
ISSN :
14203049 and 41929462
Volume :
24
Issue :
17
Database :
Directory of Open Access Journals
Journal :
Molecules
Publication Type :
Academic Journal
Accession number :
edsdoj.473de006163f41929462cd98091e5008
Document Type :
article
Full Text :
https://doi.org/10.3390/molecules24173077