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2. Bivalve Mollusks as Hosts in the Fossil Record

Author

Huntley, John Warren, De Baets, Kenneth, Scarponi, Daniele, Linehan, Liane Christine, Epa, Y. Ranjeev, Jacobs, Gabriel S., Todd, Jonathan A., Landman, Neil H., Series Editor, Harries, Peter J., Series Editor, De Baets, Kenneth, editor, and Huntley, John Warren, editor

Published
2021
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3. Molecular Imaging of Depressive Disorders

Author

Ruhé, Henricus G., Frokjaer, Vibe G., Haarman, Bartholomeus (Benno) C. M., Jacobs, Gabriël E., Booij, Jan, Dierckx, Rudi A.J.O., editor, Otte, Andreas, editor, de Vries, Erik F. J., editor, van Waarde, Aren, editor, and Sommer, Iris E., editor

Published
2021
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6. Subanesthetic Dose Ketamine in Posttraumatic Stress Disorder: A Role for Reconsolidation During Trauma-Focused Psychotherapy?

Author

Veen, Cato, Jacobs, Gabriel, Philippens, Ingrid, Vermetten, Eric, Geyer, Mark A., Series Editor, Marsden, Charles A., Series Editor, Ellenbroek, Bart A., Series Editor, Barnes, Thomas R. E., Series Editor, Andersen, Susan L., Series Editor, Vermetten, Eric, editor, Baker, Dewleen G., editor, and Risbrough, Victoria B., editor

Published
2018
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11. Translational evaluation of novel selective orexin-1 receptor antagonist JNJ-61393215 in an experimental model for panic in rodents and humans

Author

Salvadore, Giacomo, Bonaventure, Pascal, Shekhar, Anantha, Johnson, Philip L., Lord, Brian, Shireman, Brock T., Lebold, Terry P., Nepomuceno, Diane, Dugovic, Christine, Brooks, Sander, Zuiker, Rob, Bleys, Cathy, Tatikola, Kanaka, Remmerie, Bart, Jacobs, Gabriel E., Schruers, Koen, Moyer, John, Nash, Abigail, Van Nueten, Luc G. M., and Drevets, Wayne C.

Published
2020
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13. Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS

Author

Miller, Timothy M, Cudkowicz, Merit E, Andrews, Jinsy A, Hesters, Adele, Kermorvant, Hugo, Lacomblez, Lucette, Forestier, Nadine Le, Lenglet, Thimotée, Retail, Maryvonne, Ruiz Del Mar Amador, Maria, Salachas, François, Shotar, Eimad, Sourour, Nader, Babu, Suma, Dorst, Johannes, Froehlich, Elke, Fromm, Andrea, Kandler, Katharina, Langer, Eva, Leichtle, Sarah, Ludolph, Albert, Mayer, Kristina, Michels, Sebastian, Raubold, Sabine, Benatar, Michael, Schuster, Joachim, Weiland, Ulrike, Wiesenfarth, Maximilian, Witzel, Simon, Calvo, Andrea, Canosa, Antonio, Casale, Federico, Chiò, Adriano, Fuda, Giuseppe, Grassano, Maurizio, McDermott, Christopher J, Marchese, Giulia, Moglia, Cristina, Palumbo, Francesca, Salamone, Paolina, Ajiki, Takahiro, Akasaka, Aya, Ando, Masahiro, Arata, Hitoshi, Asuka, Kitamura, Baba, Kosuke, Cochrane, Thos, Bekku, Goichi, Chiba, Tomoya, Date, Yugaku, Eriko, Takeuchi, Hashiguchi, Akihiro, Hatatori, Ritsuko, Hayano, Eri, Hayashi, Yuto, Higashi, Keiko, Higuchi, Eriko, Chary, Sowmya, Hiramatsu, Yu, Horikawa, Rui, Ikenaka, Kensuke, Ishiura, Hiroyuki, Ito, Daisuke, Kawai, Sachiko, Kikuchi, Junko, Kuzuyama, Haruko, Li, Xuehong, Matsumoto, Chika, Chew, Sheena, Matsuura, Eiji, Michizono, Kumiko, Mitsui, Jun, Mitsutake, Akihiko, Mochizuki, Hideki, Nagamatsu, Akemi, Nagano, Seiichi, Nakamura, Tomonori, Naruse, Hiroya, Ogasawara, Asuka, Zhu, Han, Okada, Kensuke, Okamoto, Yuji, Okuno, Tatsusada, Oyama, Satoshi, Ozono, Tatsuhiko, Sakiyama, Yusuke, Sakuishi, Kaori, Seki, Morinobu, Shibata, Shota, Shimizu, Mikito, Wu, Fan, Takahata, Katsunori, Takahito, Yoshizaki, Takashima, Hiroshi, Takeichi, Hiroko, Tashiro, Yuichi, Toda, Tatsushi, Tomizu, Yuki, Tomoya, Wadayama, Ujiakira, Nishiike, Yashita, Daiki, Nestorov, Ivan, Al-Chalabi, Ammar, Alix, James, Bangalore, Priyadarshini, Blackburn, Daniel, Chiwera, Theresa, Clegg, Rosie, Collins, Alexis, Cooper-Knock, Jonathan, Emery, Anna, Franklin, John, Genge, Angela, Graham, Danielle, Green, Louisa, Harvey, Callum, Hobson, Esther, Islam, Mahjabim, Jenkins, Thomas Michael, Kazoka, Mbombe, Kelly, Gillian, Korley, Mercy, Madarshahaian, Daniel, Mayl, Keith, Sun, Peng, McDermott, Christopher John, Radford, Alex, Shaw, Christopher, Shaw, Pamela J, Sidebottom, Joe, Smart, Lynne, Sreedharan, Jemeen, Stone, Ben, Tsironis, Theocharis, Tuddenham, Lee, McNeill, Manjit, Verber, Nick, Wollff, Helen, Young, Stacy, Zis, Panagiotis, Adamo, Ashley, Ahmed, Arubah, Ajroud-Driss, Senda, Alameda, Gustave, Arcila-Londono, Ximena, Fanning, Laura, Baird, Candy, Bazan, Tracy, Berry, James, Bordeau, Jane, Bradford, Wendy, Brook, Nyda, Brown, Lauren, Bucelli, Robert C, Ferguson, Toby A, Buckner, Katherine, Budler, Michael W, Burba, Lindita, Burke, Katherine, Calhoun, Ashley D, Campbell, Sarah, Carey, Judith, Caristo, Irys B, Carty, Simon, Chan, Emmanuel, Fradette, Stephanie, Chaudhry, Vinay, Chen, Ricky, Chow, Saephanh, Clawson, Lora L, Clemens, Mitchell, Cloninger, Suzann E, Coleman-Wood, Krista, Cooper, Thomas N, Cummings, Arlena, Daniels, Jacquelyn, VALOR, DeSaro, Pamela, DeWitt, Michelle, Dedi, Brixhilda, Dempsey, Debbie, Denny, Carol, Doherty, Jenna, Doherty, Leana, Donahue, Megan, Doyle, Michael, Duncan, Jessie, Group, OLE Working, Elman, Lauren, Eloge, Christine M, Echiti, Desirae R, Ferrey, Dominic, Fournier, Christina, Fukumura, Yuriko, Gallagher, Katherine, Garaycoa, Jessica, Garrett, Mark, Gibson, Richard L, Beullens, Lien, Gifford, Ryan, Glass, Jonathan D, Gogol, Danuta, Golden, Shea, Gonzalez, Alexa, Goodman, Ira, Goolsby, Christopher, Goslin, Kimberly, Goulbourne, Michael, Granit, Volkan, Claeys, Kristl, Grignon, Anne-Laure, GuhaRay, Adreeja, Guide, Debra, Gundogdu, Melek Betul, Gutierrez, Gil, Hastings, Debbie, Hayzen, Colleen, Herzog, Hilary, Holloway, Raegan, Jacobs, Gabriel, Claeys, Thomas, Jacobsen, Bill, James, Virginia, Jenkins, Liberty, Jockel-Balsarotti, Jennifer, Johnson, Linda Carol, Jose, Sunil, Joslin, Benjamin, Karanja, Elizabeth, Katz, Jonathan, Keener, Anthony, Couwelier, Goedele, Kittle, Gale, Klein, Sara, Kreple, Collin, Rebecca, Rebecca, Kuenzler, Kuenzler, Kusnir, Jorge, Labbe, Kristen, Lachica-Encinas, Nicolet, Ladha, Shafeeq, Leimer, Lesli, D'Hondt, Ann, Levy, Michael, Levy, Wendy, Li, Yingji, Likanje, Marie-France, Livigni, Rebecca, Locatelli, Eduardo, Luppino, Sarah, Malcolm, Amber, Maragakis, Nicholas, Marin, Horia, Debien, Elisa, Markowitz, Clyde, Markway, Jesse, McCaffrey, Alexandra, McCoy, Arita, McCoy Gross, Kelly, Mehta, Kush, Meyer, Robert, Milan, Jennifer, Miller, Timothy, Miller, Robert G, de Keersmaecker, Sebastiaan, Morales, Francisco, Mosmiller, Elizabeth, Mott, Donovan, Moulton, Kelsey, Murphy, Christine A, Negron, Tirso, Nelson, Cassandra, Newman, Daniel S, Nissinen, Janne Kristoffer, Norman, Andrew, Della Faille, Laetitia, Ohkubo, Takuya, Olney, Nicholas, Ortiz, Natasha, Oskarsson, Bjorn, Pace, Mitchell, Packard, Kathleen, Padgett, Denny, Paganoni, Sabrina, Paredes, Maria E, Parker, Elizabeth, Delmotte, Koen, Partlow, Ann, Pattee, Gary L, Paulett, Jany, Pelot, Antoinette, Pfeifer, Kyle M, Pijanowski, Olivia, Pioro, Erik, Polak, Meraida, Prakash, Ahalya, Previte, Rosemarie, Depoortere, Sofie, Pukenas, Bryan, Quinn, Colin, Ravits, John, Razavi, Ryan, Regan, Tyler, Riley, Kristen M, Roth, Heather, Sanders, Danica, Scalia, Jennifer, Schmidt, Emma, de Velder, Laura, Schwen, Edward, Shah, Jaimin, Shah, Stuti, Shefner, Jeremy, Sheldon, Danielle, Simmons, Karon, Singh, Navneet K, Singleton, Jessica, Smiley, Richard, Smith, William B, Dobbels, Laurens, Smith, Sean, Sotirchos, Elias, Sorenson, Eric, Staff, Nathan, Steele, Julie, Steijlen, Kara, Stirrat, Taylor, Stoica, George S, Strong, Stephanie, Sufit, Robert, Sobue, Gen, Gijs, Jeroen, Sultze, Jane, Swartz, Amy, Szymanski, April, Tay, Anna, Thakore, Nimish, Thiessen, Diana, Thotala, Sukrutha, Trudell, Randall G, Turcotte, Nicole, Turner, Michelle, Horckmans, Simon, Uchil, Alpa, Upadhyay, Vihar, Usman, Uzma, Vallis, Anne, Vaporean-Bussey, Danielle, Vladimirova, Valentine, Weber, Harli, Winbigler, Jennifer, Wojanowski, Heather, Wulf, Charlie, Lamaire, Nikita, Yasek, Julia, Yoo, Stephanie, Zivalic, Hannah, Cole, Alexandra, File, Greta, Foate, Jeremy, Mason, Deborah, Newton, Susan, Roberts, Stephen, Sellwood, Cory Dean, Liessens, Hannelore, Swan, James, Werno, Anja, Zhong, Cathy, Masrori, Pegah, Nysten, Celine, Schotte, Caroline, Serrien, Anouk, Swinnen, Bart, Tilkin, Petra, van Daele, Sien, Van Damme, Philip, Vynckier, Jan, Wouters, Anke, Abrahao, Agessandro, Angle, Mark, Badawy, Mohamed, Berube, Maxime, Bertone, Vanessa, Cooper, Sarah Marie, Dobrowolski, Peter, Fong, Helen, Hannouche, Matthew, Hartley, Denise, Hogan, Michael, Johnston, Wendy, Khalfallah, Yousra, Korngut, Lawrence, Kroetsch, Gina, Letourneau, Justin, Magnussen, Claire, Martinez, Jose, Massie, Rami, Mobach, Theodore, Mookshah, Jahan, Ozelsel, Timur, Parks, Andrea, Petrillo, Janet, Pfeffer, Gerald, Ludolph, Albert C, Pham, Shirley, Phung, Liane, Shiungsun, Rodney, Pi-Shan, Li, Santos, Denizart, Salmon, Kristiana, Saunders, Natalie, Sembinelli, Dylan, Tymkow, Kelsey, Wong, Berchman, Zinman, Lorne, Karlsborg, Merete, Pedersen Lomholt, Therese, Nilsson, Sigrid, Salvesen, Lisette, Skov, Pernille, Svenstrup, Kristen, Bruneteau, Gaelle, Calerencon, Frederic, and Guimaraes Costa, Raquel

Subjects
Adult, drug effects [Recovery of Function], Spinal, Oligonucleotides, blood [Neurofilament Proteins], administration & dosage [Oligonucleotides, Antisense], tofersen, Injections, blood [Amyotrophic Lateral Sclerosis], pharmacology [Oligonucleotides, Antisense], Superoxide Dismutase-1, Double-Blind Method, Neurofilament Proteins, Humans, ddc:610, Antisense, Injections, Spinal, Biomarkers, Recovery of Function, Amyotrophic Lateral Sclerosis, Oligonucleotides, Antisense, blood [Biomarkers], drug therapy [Amyotrophic Lateral Sclerosis], therapeutic use [Oligonucleotides, Antisense], SOD1 protein, human, General Medicine, genetics [Superoxide Dismutase-1], genetics [Amyotrophic Lateral Sclerosis], cerebrospinal fluid [Biomarkers], cerebrospinal fluid [Superoxide Dismutase-1], cerebrospinal fluid [Amyotrophic Lateral Sclerosis]
Abstract

The intrathecally administered antisense oligonucleotide tofersen reduces synthesis of the superoxide dismutase 1 (SOD1) protein and is being studied in patients with amyotrophic lateral sclerosis (ALS) associated with mutations in SOD1 (SOD1 ALS).In this phase 3 trial, we randomly assigned adults with SOD1 ALS in a 2:1 ratio to receive eight doses of tofersen (100 mg) or placebo over a period of 24 weeks. The primary end point was the change from baseline to week 28 in the total score on the ALS Functional Rating Scale-Revised (ALSFRS-R; range, 0 to 48, with higher scores indicating better function) among participants predicted to have faster-progressing disease. Secondary end points included changes in the total concentration of SOD1 protein in cerebrospinal fluid (CSF), in the concentration of neurofilament light chains in plasma, in slow vital capacity, and in handheld dynamometry in 16 muscles. A combined analysis of the randomized component of the trial and its open-label extension at 52 weeks compared the results in participants who started tofersen at trial entry (early-start cohort) with those in participants who switched from placebo to the drug at week 28 (delayed-start cohort).A total of 72 participants received tofersen (39 predicted to have faster progression), and 36 received placebo (21 predicted to have faster progression). Tofersen led to greater reductions in concentrations of SOD1 in CSF and of neurofilament light chains in plasma than placebo. In the faster-progression subgroup (primary analysis), the change to week 28 in the ALSFRS-R score was -6.98 with tofersen and -8.14 with placebo (difference, 1.2 points; 95% confidence interval [CI], -3.2 to 5.5; P = 0.97). Results for secondary clinical end points did not differ significantly between the two groups. A total of 95 participants (88%) entered the open-label extension. At 52 weeks, the change in the ALSFRS-R score was -6.0 in the early-start cohort and -9.5 in the delayed-start cohort (difference, 3.5 points; 95% CI, 0.4 to 6.7); non-multiplicity-adjusted differences favoring early-start tofersen were seen for other end points. Lumbar puncture-related adverse events were common. Neurologic serious adverse events occurred in 7% of tofersen recipients.In persons with SOD1 ALS, tofersen reduced concentrations of SOD1 in CSF and of neurofilament light chains in plasma over 28 weeks but did not improve clinical end points and was associated with adverse events. The potential effects of earlier as compared with delayed initiation of tofersen are being further evaluated in the extension phase. (Funded by Biogen; VALOR and OLE ClinicalTrials.gov numbers, NCT02623699 and NCT03070119; EudraCT numbers, 2015-004098-33 and 2016-003225-41.).

Published
2022

14. Phase 1 Trial of Darigabat for the Reduction of Acute Psychological and Physiological Panic and Fear Symptoms Following CO2 Inhalation in Healthy Participants (S8.005)

Author

Gurrell, Rachel, primary, Chang, Ih, additional, Dandurand, Ann, additional, Duvvuri, Sridhard, additional, Guigliano, Amy, additional, Pastino, Gina, additional, Pham, Theresa, additional, Versavel, Stacey, additional, Jacobs, Gabriel, additional, Pour, Koshar Safai, additional, Zuiker, Rob, additional, Sanchez, Raymond, additional, and Renger, John, additional

Published
2023
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20. Gaming Frequency and Academic Performance

Author

Ip, Barry, Jacobs, Gabriel, and Watkins, Alan

Abstract

There are numerous claims that playing computer and video games may be educationally beneficial, but there has been little formal investigation into whether or not the frequency of exposure to such games actually affects academic performance. This paper explores the issue by analysing the relationships between gaming frequency--measured as the amount of time undergraduate students spend playing games in their free time--and their academic performance as measured by their examination marks. Using a sample of 713 students, correlation analyses between gaming frequency and examination performance were conducted for students of varying gaming frequency, study discipline, gender, and general attitudes towards gaming and study. The results reveal that examination marks are in fact negatively correlated with gaming frequency--.e. frequent gamers generally achieve lower marks than less frequent gamers. (Contains 12 tables and 3 figures.)

Published
2008

21. Retention and Application of Information Technology Skills among Nursing and Midwifery Students

Author

Ip, Barry, Jones, Steve, and Jacobs, Gabriel

Abstract

Pre-registration nursing and midwifery students are under considerable pressure to acquire the necessary information technology (IT) skills by the time they embark on a professional nursing career. There is a multitude of research findings detailing the use of computer-based learning materials, IT training initiatives and how such materials are beneficial to learners. There is, however, relatively little in terms of the extent to which students are given the opportunity to use such skills during study periods over an extended period of time. This paper explores related issues by presenting the results of a study into the extent to which a cohort of undergraduate nursing and midwifery students retained and applied IT knowledge six months after the initial training period. The results reveal an interesting disparity between the skills taught and their retention and use in practice. Concerns are raised over the risk of such skills being forgotten by the time students enter professional nursing careers. (Contains 1 figure and 4 tables.)

Published
2007
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22. Ring Fenced Research: The Case of Computer-Assisted Learning in Health Sciences

Author

Jacobs, Gabriel and Ip, Barry

Abstract

Interdisciplinary research is being promoted in many quarters as the way forward, but "research islands" still persist. Taking computer-assisted learning (CAL) within health sciences as a case in point, this paper describes a detailed study of the references to source material within papers published in general medical, specific nursing and general information and communications technology journals as pointing to papers published either in the same category of journal or journals of other categories. The results show that research within this area exhibits a disquieting inbred approach. Furthermore, there is clear evidence of a tendency amongst the papers examined to cite research published in journals with broadly the same impact factors as the journal in which the papers themselves are published. A discussion of the value of journal impact factors, which are a crude but useful index of the quality of journal, and their possible effect on the future of research in CAL within health sciences is embedded in the paper.

Published
2005
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23. Hypermedia and Discovery Based Learning: What Value?

Author

Jacobs, Gabriel

Abstract

In 1992, I published a paper entitled "Hypermedia and discovery based learning: A historical perspective". It traced the swings in the history of educational thinking between, on the one hand, support for conventional curriculum based learning and, on the other, the non-linear approach expressed by many educational commentators over the centuries. As I saw things, hyperlink technology would finally allow learning truly to mesh with the free association characteristics of the human mind. Once the technology had matured, it would be a teaching resource that would transform passive learners into active thinkers. Thirteen years on, I take a critical look at those optimistic conclusions. Are students better equipped to learn than previously? Are they able to think reflectively to a greater degree than their counterparts of a decade or two ago? This present paper addresses such questions, the result being that the guarded optimism of 1992 has turned to a deep pessimism.

Published
2005

24. Vocabulary and Neural Networks in the Computational Assessment of Texts Written by Second-Language Learners.

Author

Meara, Paul, Rodgers, Catherine, and Jacobs, Gabriel

Abstract

Explores the potential of a neural network in language assessment. Nonnative speakers of French were asked to produce a short text in response to a picture stimulus. A neural network was trained to grade the text on the basis of codings. Results suggest that it may be possible to teach a neural network to mimic the judgments made by human markers. (Author/VWL)

Published
2000

27. Treacherous Allies: Foreign Language Grammar Checkers.

Author

Jacobs, Gabriel and Rodgers, Catherine

Abstract

Discusses the use of a French computerized grammar checker as a learning and teaching resource. Presents the results of a controlled series of experiments in which groups of students were given the task of correcting French texts containing grammatical, lexical, and orthographical errors using an on-screen grammar checker or grammar books and dictionaries. (Author/VWL)

Published
1999

28. An American Foreign Language Immersion Program: How To. CAL-ERIC/CLL Series on Languages and Linguistics, No. 59.

Author

ERIC Clearinghouse on Languages and Linguistics, Washington, DC. and Jacobs, Gabriel H. L.

Abstract

An immersion program in a public elementary school in Montgomery County, Maryland, uses French as the medium of instruction in academic subjects. The program is based on the theory that language is learned best when there is a need to understand and communicate in that language. All students are eligible for enrollment in the multi-age classes. The Montgomery County curriculum is followed, using French materials. The major aims of the program are for the children to master their school subjects and to acquire substantive fluency in French. Standardized test results show the immersion students to be comparable in ability and achievement to their peers in English-speaking American classes and in French immersion classes in Canada. Immersion in general requires a great deal of planning and extra effort on the part of the teachers. Parents, other adults, and high school students work in the classroom to assist the teachers and to learn French. The program's only added cost to the school system is for foreign language materials. (Author/NCR)

Published
1978

30. Evaluating Courseware: Some Critical Questions.

Author

Jacobs, Gabriel

Abstract

Identifies critical questions with respect to the evaluation process in the design, development and use of courseware. Argues that certain fundamental difficulties in quantifying and judging effectiveness and learning outcomes might lead one to abandon formal evaluation; awareness of those difficulties is important for developers and teachers deciding on the caliber of a piece of educational software. (AEF)

Published
1998

31. Does Relevance to Work Mean Learning to Work? Are Government Policy and Student Pressure Downgrading Higher Education in the UK?

Author

Jacobs, Gabriel

Abstract

Government policy and student pressures are focused on future employability and appear intent on forcing higher education to be more transparently relevant to the workplace. This trend is threat to a broader view of education and the development of inquiring, innovative, critical thinkers, who are supposed to be in demand by employers. (SK)

Published
1998

32. ISDN-based Distance Learning: Tangible Costs, Intangible Benefits.

Author

Jacobs, Gabriel and Rodgers, Catherine

Abstract

Analyzes the case of a trans-European video-teaching link principally from the standpoint of the expenditure required to implement and run it, set against the benefits it offers. Considers fixed and recurrent costs. Concludes that, despite enthusiasms in the literature and in official reports for interactive tele-teaching, the financial burden it imposes may, in most cases, outweigh the benefits. (AEF)

Published
1998

34. Remote Teaching with Digital Video: A Trans-National Experience.

Author

Jacobs, Gabriel and Rodgers, Catherine

Abstract

Analyzes the psychological, technical, administrative, organizational, institutional, and general pedagogical problems in phase one of a distance learning project. Using ISDN videoconferencing for remote interactive tutorials to provide practice for United Kingdom students at the University of Wales Swansea studying business French and HEC Liege (Belgium) students studying business English. Suggests solutions to problems encountered. (PEN)

Published
1997

36. Hypermedia and Discovery-Based Learning: A Historical Perspective.

Author

Jacobs, Gabriel

Abstract

Reviews the history of discovery-based learning, including theories of programed learning, the work of B. F. Skinner, and the impact of information technology. Rejection of discovery learning is identified, and the likelihood in the near future of a revolution in education brought about by hypermedia technology is rejected. (47 references) (MES)

Published
1992

39. A Study of Novel Exploratory Tools, Digital Technologies, and Central Nervous System Biomarkers to Characterize Unipolar Depression

Author

Sverdlov, Oleksandr, primary, Curcic, Jelena, additional, Hannesdottir, Kristin, additional, Gou, Liangke, additional, De Luca, Valeria, additional, Ambrosetti, Francesco, additional, Zhang, Bingsong, additional, Praestgaard, Jens, additional, Vallejo, Vanessa, additional, Dolman, Andrew, additional, Gomez-Mancilla, Baltazar, additional, Biliouris, Konstantinos, additional, Deurinck, Mark, additional, Cormack, Francesca, additional, Anderson, John J., additional, Bott, Nicholas T., additional, Peremen, Ziv, additional, Issachar, Gil, additional, Laufer, Offir, additional, Joachim, Dale, additional, Jagesar, Raj R., additional, Jongs, Niels, additional, Kas, Martien J., additional, Zhuparris, Ahnjili, additional, Zuiker, Rob, additional, Recourt, Kasper, additional, Zuilhof, Zoë, additional, Cha, Jang-Ho, additional, and Jacobs, Gabriel E., additional

Published
2021
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41. sj-docx-1-tpp-10.1177_20451253211036814 ��� Supplemental material for MTORC1 signaling as a biomarker in major depressive disorder and its pharmacological modulation by novel rapid-acting antidepressants

Author

Cholewinski, Tomasz, Pereira, Diana, Moerland, Matthijs, and Jacobs, Gabriel E.

Subjects
FOS: Clinical medicine, 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
Abstract

Supplemental material, sj-docx-1-tpp-10.1177_20451253211036814 for MTORC1 signaling as a biomarker in major depressive disorder and its pharmacological modulation by novel rapid-acting antidepressants by Tomasz Cholewinski, Diana Pereira, Matthijs Moerland and Gabriel E. Jacobs in Therapeutic Advances in Psychopharmacology

Published
2021
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42. Supplementary_material – Supplemental material for Characterisation of the pharmacodynamic effects of the P2X7 receptor antagonist JNJ-54175446 using an oral dexamphetamine challenge model in healthy males in a randomised, double-blind, placebo-controlled, multiple ascending dose trial

Author

Recourt, Kasper, Aart, Jasper Van Der, Jacobs, Gabriel, Kam, Marieke De, Drevets, Wayne, Nueten, Luc Van, Kawita Kanhai, Siebenga, Pieter, Zuiker, Rob, Ravenstijn, Paulien, Timmers, Maarten, Gerven, Joop Van, and Boer, Peter De

Subjects
FOS: Psychology, FOS: Clinical medicine, 170199 Psychology not elsewhere classified, 110319 Psychiatry (incl. Psychotherapy), 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified, 110904 Neurology and Neuromuscular Diseases
Abstract

Supplemental material, Supplementary_material for Characterisation of the pharmacodynamic effects of the P2X7 receptor antagonist JNJ-54175446 using an oral dexamphetamine challenge model in healthy males in a randomised, double-blind, placebo-controlled, multiple ascending dose trial by Kasper Recourt, Jasper van der Aart, Gabriel Jacobs, Marieke de Kam, Wayne Drevets, Luc van Nueten, Kawita Kanhai, Pieter Siebenga, Rob Zuiker, Paulien Ravenstijn, Maarten Timmers, Joop van Gerven and Peter de Boer in Journal of Psychopharmacology

Published
2020
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45. Characterisation of the pharmacodynamic effects of the P2X7 receptor antagonist JNJ-54175446 using an oral dexamphetamine challenge model in healthy males in a randomised, double-blind, placebo-controlled, multiple ascending dose trial

Author

Recourt, Kasper, primary, van der Aart, Jasper, additional, Jacobs, Gabriel, additional, de Kam, Marieke, additional, Drevets, Wayne, additional, van Nueten, Luc, additional, Kanhai, Kawita, additional, Siebenga, Pieter, additional, Zuiker, Rob, additional, Ravenstijn, Paulien, additional, Timmers, Maarten, additional, van Gerven, Joop, additional, and de Boer, Peter, additional

Published
2020
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