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176 results on '"Jaaskelainen, T."'

1. Photoelectric Response of Bacteriorhodopsin in Thin PVA Films and Its Model

Author

Frydrych, M., Lensu, L., Parkkinen, S., Parkkinen, J., Jaaskelainen, T., Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Dough, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, De Gregorio, Massimo, editor, Di Maio, Vito, editor, Frucci, Maria, editor, and Musio, Carlo, editor

Published
2005
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10. Application of non-HDL cholesterol for population-based cardiovascular risk stratification : results from the Multinational Cardiovascular Risk Consortium

Author

Brunner, Fabian J., Waldeyer, Christoph, Ojeda, Francisco, Salomaa, Veikko, Kee, Frank, Sans, Susana, Thorand, Barbara, Giampaoli, Simona, Brambilla, Paolo, Tunstall-Pedoe, Hugh, Moitry, Marie, Iacoviello, Licia, Veronesi, Giovanni, Grassi, Guido, Mathiesen, Ellisiv B., Soderberg, Stefan, Linneberg, Allan, Brenner, Hermann, Amouyel, Philippe, Ferrieres, Jean, Tamosiunas, Abdonas, Nikitin, Yuriy P., Drygas, Wojciech, Melander, Olle, Joeckel, Karl-Heinz, Leistner, David M., Shaw, Jonathan E., Panagiotakos, Demosthenes B., Simons, Leon A., Kavousi, Maryam, Vasan, Ramachandran S., Dullaart, Robin P. F., Wannamethee, S. Goya, Risérus, Ulf, Shea, Steven, de Lemos, James A., Omland, Torbjorn, Kuulasmaa, Kari, Landmesser, Ulf, Blankenberg, Stefan, Zeller, T., Lackner, K., Wild, P., Peters, A., Meisinger, C., Voelzke, H., Doerr, M., Nauck, M., Schoettker, B., Lorenz, T., Makarova, N., Schmidt, B., Klotsche, J., Koenig, W., Kontto, J., Mannisto, S., Jaaskelainen, T., Niiranen, T., Jousilahti, P., Metspalu, A., Alver, M., Donfrancesco, C., Signorini, S. G., Gianfagna, F., Costanzo, S., Woodward, M., Dobson, A., Giles, G., Hodge, A., Magliano, D. J., Wilsgaard, T., Lyngbakken, M. N., Hveem, K., Eliasson, M., Engstrom, G., Ingelsson, M., Jorgensen, T., Twerenbold, R., Dallongeville, J., Malyutina, S., Pajak, A., Bobak, M., Whincup, P., Pitsavos, C., Benjamin, E. J., Bakker, S. J. L., Ikram, M. K., Brunner, Fabian J., Waldeyer, Christoph, Ojeda, Francisco, Salomaa, Veikko, Kee, Frank, Sans, Susana, Thorand, Barbara, Giampaoli, Simona, Brambilla, Paolo, Tunstall-Pedoe, Hugh, Moitry, Marie, Iacoviello, Licia, Veronesi, Giovanni, Grassi, Guido, Mathiesen, Ellisiv B., Soderberg, Stefan, Linneberg, Allan, Brenner, Hermann, Amouyel, Philippe, Ferrieres, Jean, Tamosiunas, Abdonas, Nikitin, Yuriy P., Drygas, Wojciech, Melander, Olle, Joeckel, Karl-Heinz, Leistner, David M., Shaw, Jonathan E., Panagiotakos, Demosthenes B., Simons, Leon A., Kavousi, Maryam, Vasan, Ramachandran S., Dullaart, Robin P. F., Wannamethee, S. Goya, Risérus, Ulf, Shea, Steven, de Lemos, James A., Omland, Torbjorn, Kuulasmaa, Kari, Landmesser, Ulf, Blankenberg, Stefan, Zeller, T., Lackner, K., Wild, P., Peters, A., Meisinger, C., Voelzke, H., Doerr, M., Nauck, M., Schoettker, B., Lorenz, T., Makarova, N., Schmidt, B., Klotsche, J., Koenig, W., Kontto, J., Mannisto, S., Jaaskelainen, T., Niiranen, T., Jousilahti, P., Metspalu, A., Alver, M., Donfrancesco, C., Signorini, S. G., Gianfagna, F., Costanzo, S., Woodward, M., Dobson, A., Giles, G., Hodge, A., Magliano, D. J., Wilsgaard, T., Lyngbakken, M. N., Hveem, K., Eliasson, M., Engstrom, G., Ingelsson, M., Jorgensen, T., Twerenbold, R., Dallongeville, J., Malyutina, S., Pajak, A., Bobak, M., Whincup, P., Pitsavos, C., Benjamin, E. J., Bakker, S. J. L., and Ikram, M. K.

Abstract

Background The relevance of blood lipid concentrations to long-term incidence of cardiovascular disease and the relevance of lipid-lowering therapy for cardiovascular disease outcomes is unclear. We investigated the cardiovascular disease risk associated with the full spectrum of bloodstream non-HDL cholesterol concentrations. We also created an easy-to-use tool to estimate the long-term probabilities for a cardiovascular disease event associated with non-HDL cholesterol and modelled its risk reduction by lipid-lowering treatment. Methods In this risk-evaluation and risk-modelling study, we used Multinational Cardiovascular Risk Consortium data from 19 countries across Europe, Australia, and North America. Individuals without prevalent cardiovascular disease at baseline and with robust available data on cardiovascular disease outcomes were included. The primary composite endpoint of atherosclerotic cardiovascular disease was defined as the occurrence of the coronary heart disease event or ischaemic stroke. Sex-specific multivariable analyses were computed using non-HDL cholesterol categories according to the European guideline thresholds, adjusted for age, sex, cohort, and classical modifiable cardiovascular risk factors. In a derivation and validation design, we created a tool to estimate the probabilities of a cardiovascular disease event by the age of 75 years, dependent on age, sex, and risk factors, and the associated modelled risk reduction, assuming a 50% reduction of non-HDL cholesterol. Findings Of the 524 444 individuals in the 44 cohorts in the Consortium database, we identified 398 846 individuals belonging to 38 cohorts (184 055 [48.7%] women; median age 51.0 years [IQR 40.7-59.7]). 199 415 individuals were included in the derivation cohort (91 786 [48.4%] women) and 199 431 (92 269 [49.1%] women) in the validation cohort. During a maximum follow-up of 43.6 years (median 13.5 years, IQR 7.0-20.1), 54 542 cardiovascular endpoints occurred. Incidence curv

Published
2019
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11. Classification of the reflectance spectra of pine, spruce, and birch

Author

Jaaskelainen, T., Silvennoinen, R., Hiltunen, J., and Parkkinen, J.P.S.

Subjects
Reflectance spectroscopy -- Usage, Reflectance -- Research, Pine -- Research, Spruce -- Research, Birch -- Research, Astronomy, Physics
Abstract

Statistical pattern-recognition methods are applied to the classification of the reflectance spectra of growing trees (Scots pine, Norway spruce, and birch). We show by using large training sets that it is possible to develop classification filters that are able to discriminate the tree types with a very high probability. Our approach may offer a reference coordinate system for multispectral remote sensing of different levels of forest damage.

Published
1994

15. Genetic variation in FTO and mortality

Author

Zimmermann, E., Angquist, L.H., Mirza, S.S., Zhao, J.H., Chasman, D.I., Fischer, K., Qi, Q., Smith, A.V., Thinggaard, M., Jarczok, M.N., Nalls, M.A., Trompet, S., Timpson, N.J., Schmidt, B., Jackson, A.U., Lyytikainen, L.P., Verweij, N., Mueller-Nurasyid, M., Vikstrom, M., Marques-Vidal, P., Wong, A., Meidtner, K., Middelberg, R.P., Strawbridge, R.J., Christiansen, L., Kyvik, K.O., Hamsten, A., Jaaskelainen, T., Tjonneland, A., Eriksson, J.G., Whitfield, J.B., Boeing, H., Hardy, R., Vollenweider, P., Leander, K., Peters, A., Harst, P. van der, Kumari, M., Lehtimaki, T., Meirhaeghe, A., Tuomilehto, J., Jockel, K.H., Ben-Shlomo, Y., Sattar, N., Baumeister, S.E., Smith, G.D., Casas, J.P., Houston, D.K., Marz, W., Christensen, K., Gudnason, V., Hu, F.B., Metspalu, A., Ridker, P.M., Wareham, N.J., Loos, R.J.F., Tiemeier, H., Sonestedt, E., Sorensen, T.I.A., The FTO-Mortality Collaborating, Epidemiology, Surgery, Erasmus MC other, Child and Adolescent Psychiatry / Psychology, FTO-Mortality Collaborating Group, Orho-Melander, M., Zillikens, C., Ikram, A., Hofman, A., Luan, J., Khaw, KT., Rose, LM., Läll, K., Mägi, R., Qi, L., Sun, Q., Harris, TB., Launer, LJ., Eiriksdottir, G., Kleber, ME., Delgado, G., Liu, Y., Garcia, M., Teumer, A., Grabe, H., Homuth, G., Jukema, JW., Ford, I., de Craen AJ., Gallacher, J., Yarnell, J., Mahabadi, AA., Nöthen, MM., Erbel, R., Stringham, HM., Boehnke, M., Amouyel, P., Ferrières, J., Arveiler, D., Kähönen, M., Nikus, K., Nieminen, T., Sanchez, A., Kivimaki, M., van Vliet-Ostaptchouk JV., Hampel, R., Thorand, B., De Faire, U., Nyberg, F., Kuh, D., Martin, NG., Montgomery, GW., Heath, AC., Madden, PA., Osmond, C., Pulizzi, N., Roswall, N., Halkjaer, J., Overvad, K., Uusitupa, M., Kinnunen, L., Lindström, J., Saramies, J., Keinänen-Kiukaanniemi, S., Uusitalo, H., Hussi, E., Baldassarre, D., Veglia, F., Humphries, S., Tremoli, E., and Heitmann, B.

Subjects
obesity, nutritional and metabolic diseases, Alpha-Ketoglutarate-Dependent Dioxygenase FTO, Genetic Variation, Proteins, mortality, Polymorphism, Single Nucleotide, Article, Body Mass Index, meta-analysis, Observational Studies as Topic, Humans, Genetic Predisposition to Disease, Waist Circumference, FTO, Adiposity, Genome-Wide Association Study
Abstract

Previously, a single nucleotide polymorphism (SNP), rs9939609, in the FTO gene showed a much stronger association with all-cause mortality than expected from its association with body mass index (BMI), body fat mass index (FMI) and waist circumference (WC). This finding implies that the SNP has strong pleiotropic effects on adiposity and adiposity-independent pathological pathways that leads to increased mortality. To investigate this further, we conducted a meta-analysis of similar data from 34 longitudinal studies including 169,551 adult Caucasians among whom 27,100 died during follow-up. Linear regression showed that the minor allele of the FTO SNP was associated with greater BMI (n = 169,551; 0.32 kg m(-2) ; 95% CI 0.28-0.32, P

Published
2015

18. Demonstrating nonlinear optical phenomena with Chinese tea

Author

Peiponen, K.-E., Mahaswari, R. Uma, Jaaskelainen, T., and Cong Gu

Subjects
Helium-neon lasers -- Usage, Tea -- Usage, Nonlinear optics -- Study and teaching, Physics
Abstract

Simple procedures for demonstrating self-defocusing and optical bistability for undergraduate students are presented. Both procedures use He-Ne lasers and a solution of tea leaves in alcohol. For demonstrating self-defocusing, a lens is used to focus a laser beam on the solution, and defocusing can be visualized under low and high power conditions. To demonstrate optical bistability, two lasers are intersected inside the tea solution, where one laser serves as the pump beam, and the other, the probe beam.

Published
1993

25. Photoelectric Response of Bacteriorhodopsin in Thin PVA Films and Its Model.

Author

Gregorio, Massimo, Maio, Vito, Frucci, Maria, Musio, Carlo, Frydrych, M., Lensu, L., Parkkinen, S., Parkkinen, J., and Jaaskelainen, T.

Abstract

Bacteriorhodopsin is a protein in the purple membrane of the archaean Halobacterium salinarum. Its natural function is to act as a light-driven proton pump contributing to the energy balancing mechanism in the archaean. Bacteriorhodopsin retains its proton pumping property even when isolated from the purple membrane and incorporated into an artificial membrane or polymeric film. Such bacteriorhodopsin films have been studied as a potential material for information technology. We built optical elements based on bacteriorhodopsin and measured their spectral properties. Here we describe a model of photoelectric response of the elements and compare it to the experimentally measured values. [ABSTRACT FROM AUTHOR]

Published
2005
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30. Fast effects with two-wave mixing in BTO

Author

Esselbach, M., primary, Cedilnik, G., additional, Kiessling, A., additional, Kowarschik, R., additional, Kamshilin, A. A., additional, Prokofiev, V. V., additional, and Jaaskelainen, T., additional

Published
1999
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