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A new approach to volume‐selected in vivo NMR spectroscopy uses two frequencyshifted sinc pulses, in conjunction with pulsed field gradients, to destroy the coherence of the unwanted signals. A hard π/2 pulse can then be used to read the z magnetization in the region of interest. This method is independent of T, provides complete volume selection in a single acquisition, and can be readily implemented on most high‐field commercial imaging/spectroscopy systems. © 1986 Academic Press, Inc.

When developing new techniques for NMR imaging and in vivo spectroscopy it is a major advantage to be able to calculate the magnetization slice profiles, at any point during a pulse sequence in the presence of a field gradient. While this has frequently been done by treating the problem as a number of discrete resonances, it is sometimes necessary to consider the continuous nature of the magnetization profiles. This paper describes a method used to simulate the free-induction decay at any point during the NMR experiment.