The utilization of two frequency-shifted sinc pulses for performing volume-selectedin vivoNMR spectroscopy

A new approach to volume‐selected in vivo NMR spectroscopy uses two frequencyshifted sinc pulses, in conjunction with pulsed field gradients, to destroy the coherence of the unwanted signals. A hard π/2 pulse can then be used to read the z magnetization in the region of interest. This method is independent of T, provides complete volume selection in a single acquisition, and can be readily implemented on most high‐field commercial imaging/spectroscopy systems. © 1986 Academic Press, Inc.