528 results on '"Inuzuka, Hiroyuki"'
Search Results
2. Current-in-plane magnetoresistance in chiral-molecule/ferromagnetic metal bilayer due to thermally induced spin polarization
3. Molecular insights and clinical implications for the tumor suppressor role of SCFFBXW7 E3 ubiquitin ligase
4. O-GlcNAcylation in tumorigenesis and its implications for cancer therapy
5. Prolonged hypoxia alleviates prolyl hydroxylation-mediated suppression of RIPK1 to promote necroptosis and inflammation
6. Identification of a distal enhancer regulating hedgehog interacting protein gene in human lung epithelial cells
7. PRMT1 orchestrates with SAMTOR to govern mTORC1 methionine sensing via Arg-methylation of NPRL2
8. AMPK-dependent phosphorylation of the GATOR2 component WDR24 suppresses glucose-mediated mTORC1 activation
9. PRMT1 methylates METTL14 to modulate its oncogenic function
10. Pharmacological inhibition of the SKP2/p300 signaling axis restricts castration-resistant prostate cancer
11. Targeted protein posttranslational modifications by chemically induced proximity for cancer therapy
12. Insights into the aberrant CDK4/6 signaling pathway as a therapeutic target in tumorigenesis
13. Ring domains are essential for GATOR2-dependent mTORC1 activation
14. Protein neddylation in lung tumorigenesis: Target validation and targeted therapy
15. Delayed fluorescence from inverted singlet and triplet excited states
16. Targeting micro-environmental pathways by PROTACs as a therapeutic strategy
17. Targeted Degradation of Receptor-Interacting Protein Kinase 1 to Modulate the Necroptosis Pathway.
18. Functional analysis of the emerging roles for the KISS1/KISS1R signaling pathway in cancer metastasis
19. USP7-Based Deubiquitinase-Targeting Chimeras Stabilize AMPK
20. HHIP protein interactions in lung cells provide insight into COPD pathogenesis
21. Interplay between protein acetylation and ubiquitination controls MCL1 protein stability
22. FBW7 Loss Promotes Chromosomal Instability and Tumorigenesis via Cyclin E1/CDK2–Mediated Phosphorylation of CENP-A
23. G protein–coupled receptor Gpr115 (Adgrf4) is required for enamel mineralization mediated by ameloblasts
24. Sox21 Regulates Anapc10 Expression and Determines the Fate of Ectodermal Organ
25. Structurally Specific Z-DNA Proteolysis Targeting Chimera Enables Targeted Degradation of Adenosine Deaminase Acting on RNA 1
26. Skp2 dictates cell cycle-dependent metabolic oscillation between glycolysis and TCA cycle
27. Acetylation-dependent regulation of PD-L1 nuclear translocation dictates the efficacy of anti-PD-1 immunotherapy
28. Inhibition of CK1ε potentiates the therapeutic efficacy of CDK4/6 inhibitor in breast cancer
29. USP2 inhibition prevents infection with ACE2-dependent coronaviruses in vitro and is protective against SARS-CoV-2 in mice
30. Physiological functions of FBW7 in cancer and metabolism
31. Methylated Nucleotide-Based Proteolysis-Targeting Chimera Enables Targeted Degradation of Methyl-CpG-Binding Protein 2
32. Conclusions and Research Perspectives
33. The Role of APC E3 Ubiquitin Ligase Complex in Tumorigenesis
34. Introduction
35. The Role of FBXO Subfamily of F-box Proteins in Tumorigenesis
36. The Role of FBXL Subfamily of F-box Proteins in Tumorigenesis
37. The Role of FBXW Subfamily of F-box Proteins in Tumorigenesis
38. NOTCH2 Hajdu-Cheney Mutations Escape SCFFBW7-Dependent Proteolysis to Promote Osteoporosis
39. SCFβ-TRCP E3 ubiquitin ligase targets the tumor suppressor ZNRF3 for ubiquitination and degradation
40. Data from The APC/C E3 Ligase Complex Activator FZR1 Restricts BRAF Oncogenic Function
41. Supplementary Methods, Figure Legends, Figures S1 - S7, Table S1 - Supplementary Figure S1 from The APC/C E3 Ligase Complex Activator FZR1 Restricts BRAF Oncogenic Function
42. pVHL suppresses kinase activity of Akt in a proline-hydroxylation-dependent manner
43. Data from FBW7 Loss Promotes Chromosomal Instability and Tumorigenesis via Cyclin E1/CDK2–Mediated Phosphorylation of CENP-A
44. Table S1 from FBW7 Loss Promotes Chromosomal Instability and Tumorigenesis via Cyclin E1/CDK2–Mediated Phosphorylation of CENP-A
45. Figure S1-S7 from FBW7 Loss Promotes Chromosomal Instability and Tumorigenesis via Cyclin E1/CDK2–Mediated Phosphorylation of CENP-A
46. Aging and cancer hallmarks as therapeutic targets
47. An intrinsic connection between COVID-19 and aging
48. SPOP Promotes Ubiquitination and Degradation of the ERG Oncoprotein to Suppress Prostate Cancer Progression
49. Author Correction: Skp2 dictates cell cycle-dependent metabolic oscillation between glycolysis and TCA cycle
50. Prostate cancer-associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4
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