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Prostate cancer-associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4

Authors :
Dai, Xiangpeng
Gan, Wenjian
Li, Xiaoning
Wang, Shangqian
Zhang, Wei
Huang, Ling
Liu, Shengwu
Zhong, Qing
Guo, Jianping
Zhang, Jinfang
Chen, Ting
Shimizu, Kouhei
Beca, Francisco
Blattner, Mirjam
Vasudevan, Divya
Buckley, Dennis L
Qi, Jun
Buser, Lorenz
Liu, Pengda
Inuzuka, Hiroyuki
Beck, Andrew H
Wang, Liewei
Wild, Peter J
Garraway, Levi A
Rubin, Mark A
Barbieri, Christopher E
Wong, Kwok-Kin
Muthuswamy, Senthil K
Huang, Jiaoti
Chen, Yu
Bradner, James E
Wei, Wenyi
Source :
Nature Medicine. September, 2017, Vol. 23 Issue 9, p1063, 9 p.
Publication Year :
2017

Abstract

Author(s): Xiangpeng Dai [1]; Wenjian Gan [1]; Xiaoning Li [1, 2]; Shangqian Wang [3]; Wei Zhang [4, 5]; Ling Huang [6]; Shengwu Liu [7, 8]; Qing Zhong [9]; Jianping Guo [...]

Details

Language :
English
ISSN :
10788956
Volume :
23
Issue :
9
Database :
Gale General OneFile
Journal :
Nature Medicine
Publication Type :
Academic Journal
Accession number :
edsgcl.503804993
Full Text :
https://doi.org/10.1038/nm.4378