1. Muscle function and architecture in children with juvenile idiopathic arthritis
- Author
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Frédéric Dutheil, Bruno Pereira, Pascale Duché, Sébastien Ratel, Anthony Birat, Emmanuelle Rochette, Etienne Merlin, Daniel Courteix, Eric Doré, Pierre Bourdier, Laboratoire des Adaptations Métaboliques à l'Exercice en Conditions Physiologiques et Pathologiques (AME2P), Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-UFR Sciences et Techniques des Activités Physiques et Sportives - Clermont-Auvergne (UFR STAPS - UCA), Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Université Clermont Auvergne [2017-2020] (UCA [2017-2020]), CIC Clermont Ferrand, Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Gabriel Montpied [Clermont-Ferrand], CHU Clermont-Ferrand-CHU Clermont-Ferrand-Centre de Pharmacologie Clinique, CHU Clermont-Ferrand, Impact de l'Activité Physique sur la Santé (IAPS), Université de Toulon (UTLN), Laboratoire de Psychologie Sociale et Cognitive (LAPSCO), Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Centre National de la Recherche Scientifique (CNRS), Service Santé Travail Environnement [CHU Clermont-Ferrand], CHU Gabriel Montpied [Clermont-Ferrand], CHU Clermont-Ferrand-CHU Clermont-Ferrand, WittyFit, Australian Catholic University (ACU), Direction de la recherche clinique et de l’innovation [CHU Clermont-Ferrand] (DRCI), Unité de Nutrition Humaine (UNH), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Clermont Auvergne (UCA), Laboratoire des Adaptations Métaboliques à l'Exercice en Conditions Physiologiques et Pathologiques - Clermont Auvergne (AME2P), Faculté des Sciences du SportFaculté des Sciences du Sport, UFR STAPS-Université Clermont Auvergne (UCA), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre de Pharmacologie Clinique-CHU Gabriel-Montpied, Laboratoire de Psychologie Sociale et Cognitive - Clermont Auvergne (LAPSCO), Université Clermont Auvergne (UCA)-Centre National de la Recherche Scientifique (CNRS), School of Exercise Science [Melbourne, VIC, Australia] (Faculty of Health), Délégation à la recherche clinique et aux innovations (DRCI), CHU de Clermont-Ferrand, CIC - Clermont Ferrand, Institut National de la Santé et de la Recherche Médicale (INSERM), Unité de Nutrition Humaine - Clermont Auvergne (UNH), Université Clermont Auvergne (UCA)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), and LAPSCO, HAL
- Subjects
musculoskeletal diseases ,medicine.medical_specialty ,[SDV.MHEP.PHY] Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO] ,Arthritis ,intermuscular adipose tissue ,Isometric exercise ,Growth ,03 medical and health sciences ,Vertical jump ,[SDV.MHEP.PED] Life Sciences [q-bio]/Human health and pathology/Pediatrics ,0302 clinical medicine ,IMAT ,Internal medicine ,medicine ,[SDV.MHEP.PHY]Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO] ,Humans ,Quantitative computed tomography ,Child ,Muscle, Skeletal ,ComputingMilieux_MISCELLANEOUS ,Ultrasonography ,030203 arthritis & rheumatology ,Inflammation ,[SDV.MHEP.PED]Life Sciences [q-bio]/Human health and pathology/Pediatrics ,[SDV.MHEP] Life Sciences [q-bio]/Human health and pathology ,medicine.diagnostic_test ,business.industry ,Ultrasound ,Paediatrics ,030229 sport sciences ,General Medicine ,Fascicle ,medicine.disease ,Arthritis, Juvenile ,Physical activity level ,Peripheral ,Adipose Tissue ,Pediatrics, Perinatology and Child Health ,Cardiology ,[SDV.IMM]Life Sciences [q-bio]/Immunology ,Muscle ,Tomography, X-Ray Computed ,business ,[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology - Abstract
International audience; Aim: To assess muscle function and functional abilities in children with juvenile idiopathic arthritis (JIA). Methods: Fourteen children with JIA and 14 healthy controls matched for age and sex were included. Muscle characteristics, both structural (thickness, cross-sectional area (CSA) and fascicle angle) and qualitative (intermuscular adipose tissue : IMAT) were assessed on thigh muscles using ultrasound and peripheral quantitative computed tomography (pQCT). Muscle function and functional abilities were determined from the assessment of maximal voluntary isometric contraction force (MVIC) of the knee extensors and vertical jump performance. Results: No significant difference in MVIC force was observed between both groups. However, squat jump height was significantly reduced in children with JIA (18.3 ± 5.4 vs 24.3 ± 7.9 cm, p
- Published
- 2020