1. Rebound activity after fingolimod cessation: a case – control study
- Author
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Andres, Barboza, Inés, Gaitán María, Ricardo, Alonso, Célica, Ysrraelit María, Geraldine, Luetic, Susana, Liwacki, Liliana, Patrucco, Javier, Halfon Mario, Marcos, Burgos, Carolina, Mainella, Raul, Pierdabuena, Luciano, Recchia, Judith, Steinberg, Analia, Tkachuk Veronica, Gisela, Zanga, Adriana, Carra, Aníbal, Chertcoff, Nora, Fernandez Liguori, Luciana, Lazaro, Laura, Menichini Maria, Jimena, Miguez, Gabriela, Orzuza, Alfredo, Palavecino, Agustin, Pappolla, Santiago, Pigretti, Cecilia, Pita, Emiliano, Ruiz, Berenice, Silva, and Guillermo, Zentil
- Abstract
•The median time to rebound activity after fingolimod discontinuation was 50 days (IQR 37.25 – 86.75).•The main reason for stopping fingolimod in this cohort was therapeutic failure (46%).•Age, gender, MS phenotype, number of relapses in the year prior to suspension, time of exposure to fingolimod, or EDSS at the moment of suspension, were not predictors of RA.•68% of cases developed sustained worsening in EDSS after 3 months of RA.
- Published
- 2021
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