1. Vitamin E and antioxidant activity; its role in slow coronary flow
- Author
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Gürsel Yildiz, Mehmet Yilmaz, Veysel Kenan Celik, Imge Ezgi Eken, Ahmet Gurlek, Huseyin Aydin, [Celik, Veysel Kenan -- Eken, Imge Ezgi -- Aydin, Huseyin] Cumhuriyet Univ, Dept Biochem, Fac Med, Sivas, Turkey -- [Yildiz, Gursel] Ataturk State Hosp, Clin Nephrol, Zonguldak, Turkey -- [Yilmaz, Mehmet Birhan -- Gurlek, Ahmet] Cumhuriyet Univ, Dept Cardiol, Fac Med, Sivas, Turkey, YILMAZ, MEHMET BIRHAN -- 0000-0002-8169-8628, YILMAZ, Mehmet Birhan -- 0000-0002-8169-8628, and Zonguldak Bülent Ecevit Üniversitesi
- Subjects
Adult ,Male ,Antioxidant ,medicine.medical_treatment ,Radical ,slow coronary flow ,antioxidant activity ,vitamin E ,Biology ,Coronary Angiography ,medicine.disease_cause ,Antioxidants ,Superoxide dismutase ,chemistry.chemical_compound ,Coronary Circulation ,medicine ,Humans ,Free-radical theory of aging ,chemistry.chemical_classification ,Reactive oxygen species ,Superoxide ,Cardiovascular Topics ,Smoking ,General Medicine ,Middle Aged ,Lipids ,Oxidative Stress ,C-Reactive Protein ,chemistry ,Biochemistry ,Case-Control Studies ,biology.protein ,No-Reflow Phenomenon ,Female ,Hydroxyl radical ,Cardiology and Cardiovascular Medicine ,Biomarkers ,Blood Flow Velocity ,Oxidative stress - Abstract
WOS: 000337256000005, PubMed: 24337212, Aim: Oxidative stress, which is widely recognised as an important feature of many diseases, can be defined as an increased formation of reactive oxygen species or decreased antioxidant defense. In this study we measured plasma vitamin E levels and total antioxidant activity (AOA) in patients with slow coronary flow (SCF). Methods: The plasma vitamin E levels and AOA were measured in 40 patients with angiographically diagnosed SCF. Forty subjects with normal coronary flow (NCF) served as the control group. SCF and NCF were analysed, and blood samples were taken for plasma vitamin E levels and AOA. Plasma vitamin E levels and AOA in patients with SCF were evaluated and compared to those of patients with NCF. Results: There was no significant difference between the two groups in terms of plasma AOA, lipid profile and C-reactive protein (CRP) levels but there was a significant difference in vitamin E levels between the two groups (p = 0.001). Conclusion: Vitamin E levels were found to be lowered in patients with SCF compared to the NCF group. The association between smoking and vitamin E levels is worth further investigating in larger samples.
- Published
- 2013