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Vitamin E and antioxidant activity; its role in slow coronary flow
- Source :
- Cardiovascular Journal of Africa
- Publication Year :
- 2013
- Publisher :
- Clinics Cardive Publishing, 2013.
-
Abstract
- WOS: 000337256000005<br />PubMed: 24337212<br />Aim: Oxidative stress, which is widely recognised as an important feature of many diseases, can be defined as an increased formation of reactive oxygen species or decreased antioxidant defense. In this study we measured plasma vitamin E levels and total antioxidant activity (AOA) in patients with slow coronary flow (SCF). Methods: The plasma vitamin E levels and AOA were measured in 40 patients with angiographically diagnosed SCF. Forty subjects with normal coronary flow (NCF) served as the control group. SCF and NCF were analysed, and blood samples were taken for plasma vitamin E levels and AOA. Plasma vitamin E levels and AOA in patients with SCF were evaluated and compared to those of patients with NCF. Results: There was no significant difference between the two groups in terms of plasma AOA, lipid profile and C-reactive protein (CRP) levels but there was a significant difference in vitamin E levels between the two groups (p = 0.001). Conclusion: Vitamin E levels were found to be lowered in patients with SCF compared to the NCF group. The association between smoking and vitamin E levels is worth further investigating in larger samples.
- Subjects :
- Adult
Male
Antioxidant
medicine.medical_treatment
Radical
slow coronary flow
antioxidant activity
vitamin E
Biology
Coronary Angiography
medicine.disease_cause
Antioxidants
Superoxide dismutase
chemistry.chemical_compound
Coronary Circulation
medicine
Humans
Free-radical theory of aging
chemistry.chemical_classification
Reactive oxygen species
Superoxide
Cardiovascular Topics
Smoking
General Medicine
Middle Aged
Lipids
Oxidative Stress
C-Reactive Protein
chemistry
Biochemistry
Case-Control Studies
biology.protein
No-Reflow Phenomenon
Female
Hydroxyl radical
Cardiology and Cardiovascular Medicine
Biomarkers
Blood Flow Velocity
Oxidative stress
Subjects
Details
- ISSN :
- 16800745 and 19951892
- Volume :
- 24
- Database :
- OpenAIRE
- Journal :
- Cardiovascular Journal Of Africa
- Accession number :
- edsair.doi.dedup.....23a949fd5a92c27efceaead622f27781