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Spectral features of the original and irradiated with electrons with E = 2 MeV GaP light emitting diodes (LEDs) were studied. Recombination lines of the exciton bound on the N isoelectronic center and on the pair complexes NN1 were detected. The change in the spectral composition of radiation when passing through a section of negative differential resistance is analyzed. Dose dependences of luminescence intensity were obtained for green GaP(N) and red GaP(Zn-O) LEDs. The maximum critical radiation dose was established, after which the LEDs lost their characteristic exciton emission mechanism. The results of the annealing of irradiated LEDs are given.

The aim was to assess the effect of a single atorvastatin loading dose on reducing the frequency of perioperative myocardial damage. Perioperative myocardial damage is a complication of endovascular revascularization of the coronary arteries. This complication significantly aggravates the operative and life prognosis of the patients. Atorvastatin loading dose has a protective effect, which can significantly reduce the percentage of perioperative myocardial damage and therefore improve the patient’s prognosis. This article presents an analysis of studies, dedicated to the effect of atorvastatin loading dose on perioperative myocardial damage in patients with stable coronary artery disease.

Objective. To analyze the protective effect of atorvastatin loading dose on the reduction of myocardial injury associated with percutaneous coronary intervention, left ventricular systolic functionand exercise tolerancein patients with endovascular recanalization of chronic atherosclerotic total occlusions. Methods. 82 patients underwent recanalization. The patients in the main group ( n = 38) received a loading dose of atorvastatin 80 mg before surgery. Patients in control group ( n = 44) received 20 mg of atorvastatin. In both groups Troponin I, CF fraction of creatine phosphokinaseweremeasured, echocardiographyand veloergometer test were performed prior to surgery, 24 hours, 1 month, 1 year after the surgery. Results. There was no difference in Troponin I and CF fraction of creatine phosphokinase initial levels. In 24 hours in the main group in 3 patients (7,9 %) there was discovered moderate troponin I rising. In the control group there were 11 (25 %) patients with increasing in troponin I level in 5 and more times. CF fraction of creatine phosphokinase in control group was increased in 3 (7,9 %) patients, in the control group this parameter was increased in 16 (36,4 %) patients. In 1 month and 1 year Troponin Iand CF fraction of creatine phosphokinaselevel was normal in the both groups.There were no statistically significant changes in echocardiography parametersor exercise tolerance during the all follow-up period. Conclusion. Atorvastatin loading dose has a protective effect and prevents periprocedural myocardial injury. At the same time it doesn’t influence on central hemodynamics parameters measured by echocardiography.

Проаналізовано підходи вчених до визначення поняття та характеристики особливостей адміністративних процедур, подано ознаки адміністративних процедур у діяльності судів і розкрито їх значення, встановлено стадії адміністративних процедур у діяльності судів.

Доведено, що оцінювання виступає надзвичайно важливим інструментом перевірки якості, ефективності та результативності діяльності судів. Указано, що воно, забезпечуючи отримання інформації про діяльність суду, сприяє дотриманню його незалежності як органу судової влади. Установлено, що оцінювання діяльності суду здійснюється переважно у формах опитування (зовнішнього та внутрішнього) та вивчення звітності й інших документів, що містять статистичні дані про роботу судів. Здійснено їх аналіз та надано пропозиції щодо їх удосконалення.

The study objective is evaluate atherosclerosis burden on atorvastatin protective effect in patients with chronic total occlusion recanalization. Methods. 38 patients underwent recanalization of chronic total occlusions. All patients received a loading dose of atorvastatin 80 mg before surgery. Further patients were divided into high and low risk group according to SYNTAX score. In both groups, troponin I, CF fraction of creatine phosphokinase, functional parameters of the myocardium were measured 1 day prior to surgery, 24 hours and 1 month after the surgery. Results. In the high risk group there was discovered more significant troponin I rising compared with low risk group. In the low risk group troponin I level was significantly lower. CF fraction of creatine phosphokinase in both groups was similar. There were no statistically significant changes in echocardiography parameters. Conclusion. Atorvastatin loading dose has a protective effect and prevents periprocedural myocardial ischemia. At the same time this effect appears only in patients with low atherosclerosis burden - SYNTAX score less than 19.5. At the same time it doesn’t influence on central hemodynamics in short-term period.

The article is devoted to the current state of the problem of statin use in interventional cardiology. It is shown that the use of statins in patients with stable manifestations of coronary heart disease, and in patients with acute coronary syndrome has a protective effect, which is reflected in the reduction of perioperative myocardial ischemia, improvement of left ventricular systolic function, reducing the number of adverse cardiac events. It is known that the protective role of statins is associated not only with the cholesterol-lowering effect, but also with a large number of pleiotropic effects. A lot of attention is paid to the complex and problematic group of patients with chronic total occlusions of coronary arteries (CTO). The presence of CTO is associated with poor prognosis and increased mortality in long-term period. A significant problem during percutaneous coronary intervention (PCI) in patients with the CTO is a frequent development of perioperative ischemia or myocardial infarction, which is associated with an increased mortality rates within 30 days after PCI, as well as in the long-term period. Currently, mostly proved protective effect of atorvastatin. Based on the analysis of contemporary literature is concluded that statin efficacy in the prevention of complications of PCI in patients with CTO is currently not in doubt.

Effect of the reactor fast neutron flux (E = 2 MeV, Ф = 2⋅1014 n/cm2) on the current-voltage, capacitance-voltage characteristics, the electroluminescence intensity of power ІnGaN/GaN LEDs on the SіC and AuSn/Si substrates are studied. It was revealed that radiation hardness of InGaN/GaN heterostructures depend on the substrate.

In the present paper, a current state of the intellectual property institute and its correlation with the other elements of the national innovative system is examined on the example of Italy. The analysis shows an insufficiency of some important aspects such as the financing of R&D both from the business side and from the state side, the level of education of the participants of an innovative process, a level of the intellectual property protection. These leads to the gap between Italy and the world leaders of innovative development by a number of the indicators. The program of innovative development of Italy which is performed over a period of years has some positive results, particularly an increase of applications on the intellectual property registration. However, so far the applied measures are insufficient for the strengthening of Italian positions as an innovatively developed country on the international level.

The Standard Model problems lead to the new theories of extra dimensions: Randall-Sundrum model, Arkani-Hamed-Dimopoulos-Dvali model, and TeV-1 model. In the framework of these models, with the help of computer program Pythia8.2, the production cross sections for Kaluza-Klein particles at various energies at the LHC were calculated. The generation of monojet events from scalar graviton emission was considered for number of extra dimensions (n=2, 4, and 6) for the energy at the LHC 14 TeV. The graviton production processes through the gluon-gluon, quark-gluon, and quark-quark fusion processes are also studied and some periodicity was found in the behavior of the graviton mass spectrum. Production cross sections multiplied by branching fractions were calculated for the massive graviton, G, within Randall-Sundrum scenario and the most probable processes of graviton decay at 13 TeV, 14 TeV, and 100 TeV were counted.

Electroluminescence of green N-doped gallium phosphide light-emitting diodes was studied. The negative differential resistance region in the current-voltage characteristics was found at low temperature (Т ≤ 90 К). Possible reason of this phenomenon is the redistribution of recombinational flows between annihilation channels on isolated nitrogen atoms and annihilation channel on the NN1 pairs.

Serial green and red GaP light emitting diodes were studied. Structures were irradiated at room temperatures with 2 MeV electrons in pulse mode and electrical characteristics were measured at 77 – 300 K. It was observed the new stage of negative differential resistance at low temperature (90 K) and the current (< 103 mA) interval, additionally to known S-type instability. Luminescence characteristics at different temperatures and injection levels were given for all types’ diodes. Dose dependencies of luminescence intensity on electron dose and its restoring after irradiation were also presented.

Microplasma breakdowns of red and green GaP diodes were studied. It has been shown that tunneling was the main component of reverse current at the beginning of the breakdown while an avalanche current prevailed at highs breakdown current. Microplasma spectrum is considered to be the result of the overlapping of hot carrier emitting and recombination amitting of impurity level-valence band. 2 MeV electron irradiation leads to the de-crease of microplasma number due to the radiation defect creating.

Aim. To study the effects of intracoronary administration of the ischemic preconditioning (IP) trigger adenosine on the reduced incidence of percutaneous coronary intervention (PCI)-associated myocardial infarction (MI) and left ventricular (LV) systolic and contractile function in patients with type 2 diabetes mellitus (DM) during recanalization of chronic coronary occlusions (CCO). Subjects and methods. The patients were divided into 4 groups: 1) 45 patients without DM who received intracoronary placebo infusion; 2) 51 patients without DM who had 10 mg intracoronary adenosine during PCI; 3) 34 patients with type 2 DM who had intracoronary adenosine during PCI; 4) 37 with type 2 DM who received intracoronary placebo. Troponin I and the MB fraction of creatine phosphokinase were measured an hour before and 18-24 hours and 5 days after PCI. The authors estimated the incidence of PCI-associated MI according to the ESC/ACCF/AHA/WHF (2007) criteria and the time course of changes in LV ejection fraction (EF) and end-systolic volume (ESV) and end-diastolic volume, impaired LV local contractility index (ILVLCI) in 167 patients with CCO 1 day and 1 and 12 months after PCI. Results. There was an improvement in myocardial systolic and contractile function after recanalization and stenting for CCO. The intracoronary adenosine groups showed significantly reduced incidence of PCI-associated MI, increased LV EF, and decreased LV ESV and ILVLCI as compared to the placebo groups. Conclusion. The intracoronary injection of the IP trigger adenosine is an effective and safe method to improve LV systolic and contractile function in patients with CCO and type 2 DM.

The paper describes a methodology based on the genetic algorithm that permits to automate the process for obtaining optimum rule bases while applying a controller based on a fuzzy logic. Using a specific structure of a chromosome, a special mutation operation and an adequate fitness function the proposed methodology makes it possible to select a fuzzy rule base, to minimize a number of rules, rationally to place input sets of fuzzy functions and corresponding arrangement of output singletons in the form of single-element sets. The paper presents an example when the methodology allows to reduce a number of rules by two fold and, consequently, calculative control procedure without any deterioration in quality control.