Search

Your search keyword '"Hiroaki Tokuda"' showing total 2 results
Start Over Author "Hiroaki Tokuda"
2 results on '"Hiroaki Tokuda"'

1. Comparative Effects of Direct Renin Inhibitor and Angiotensin Receptor Blocker on Albuminuria in Hypertensive Patients with Type 2 Diabetes. A Randomized Controlled Trial.

Author

Takashi Uzu, Shin-Ichi Araki, Atsunori Kashiwagi, Masakazu Haneda, Daisuke Koya, Hiroki Yokoyama, Yasuo Kida, Motoyoshi Ikebuchi, Takaaki Nakamura, Masataka Nishimura, Noriko Takahara, Toshiyuki Obata, Nobuyuki Omichi, Katsuhiko Sakamoto, Ryosuke Shingu, Hideki Taki, Yoshio Nagai, Hiroaki Tokuda, Munehiro Kitada, Miwa Misawa, Akira Nishiyama, Hiroyuki Kobori, Hiroshi Maegawa, and Shiga Committee for Preventing Diabetic Nephropathy

Subjects
Medicine, Science
Abstract

In patients with diabetes, albuminuria is a risk marker of end-stage renal disease and cardiovascular events. An increased renin-angiotensin system activity has been reported to play an important role in the pathological processes in these conditions. We compared the effect of aliskiren, a direct renin inhibitor (DRI), with that of angiotensin receptor blockers (ARBs) on albuminuria and urinary excretion of angiotensinogen, a marker of intrarenal renin-angiotensin system activity.We randomly assigned 237 type 2 diabetic patients with high-normal albuminuria (10 to

Published
2016
Full Text
View/download PDF

2. New Metallochromic and Fluorescence Compounds Obtained from the Reaction of 5,8-Quinolinedione with 2-[3-(Dimethylamino)phenyl]propene

Author

Juri Okamoto, Katsuhira Yoshida, Yuji Kubo, Osamu Miyatake, and Hiroaki Tokuda

Subjects
chemistry.chemical_classification, Propene, chemistry.chemical_compound, Polycyclic compound, chemistry, Intramolecular reaction, Tertiary amine, Intense fluorescence, Intramolecular cyclization, General Chemistry, Photochemistry, Fluorescence, Quinone
Abstract

The reaction of 5,8-quinolinedione with 2-[3-(dimethylamino)phenyl]propene was initiated by HC1 to give 6-[4-(dimethylamino)-2-(2-propenyl)phenyl]quinoline-5,8-dione, which subsequently underwent intramolecular cyclization to produce new compounds with remarkable metallochromism and intense fluorescence.

Published
1991

Catalog

Books, media, physical & digital resources
See catalog results