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4. Thymus Surgery Prospectives and Perspectives in Myasthenia Gravis.

Author

Salahoru, Paul, Grigorescu, Cristina, Hinganu, Marius Valeriu, Lunguleac, Tiberiu, Halip, Alina Ioana, and Hinganu, Delia

Subjects
THYMECTOMY, MYASTHENIA gravis, ACTION potentials, POSTSYNAPTIC potential, THYMUS, MUSCLE weakness
Abstract

The thymus is a lymphoid organ involved in the differentiation of T cells, and has a central role in the physiopathogenesis of Myasthenia Gravis (MG). This connection is proved by a series of changes in the level of neuromuscular junctions, which leads to a decrease in the amplitude of the action potential in the post-synaptic membrane. Because of this, the presence of anti-cholinergic receptor antibodies (AChR), characteristic of MG, is found, which causes the progressive regression of the effect of acetylcholine at the level of neuromuscular junctions, with the appearance of muscle weakness. The thymectomy is a surgical variant of drug therapy administered to patients with MG. In the case of patients with nonthymomatous MG, thymectomy has become a therapeutic standard, despite the fact that there is no solid scientific evidence to explain its positive effect. Videothoracoscopic surgery or robotic surgery led to a decrease in the length of hospital stay for these patients. This paper aims to synthesize the information presented in the literature in order to create a background for the perspectives of thymectomy. [ABSTRACT FROM AUTHOR]

Published
2024
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10. Antithrombotic Therapy in Patients with Stroke An observational study

Author

Cuciureanu, Dan Iulian, primary, Constantinescu, Victor Alexandru, additional, Statescu, Cristian, additional, Sascau, Radu Andy, additional, Hodorog, Diana Nicoleta, additional, Preda, Cristina, additional, Hinganu, Delia, additional, Hinganu, Marius Valeriu, additional, and Cuciureanu, Tudor, additional

Published
2019
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15. Particularities of Using Contrast Agents in Diagnosis of Stroke

Author

Cuciureanu, Dan Iulian, primary, Statescu, Cristian, additional, Sascau, Radu Andy, additional, Cuciureanu, Tudor, additional, Constantinescu, Victor Alexandru, additional, Hinganu, Delia, additional, Preda, Cristina, additional, Hinganu, Marius Valeriu, additional, and Turliuc, Mihaela Dana, additional

Published
2019
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21. Labio-palatine Cleft, Morphological Substrate

Author

Romanec, Cristian, primary, Pacurar, Mariana, additional, Decusara, Mioara, additional, Scutariu, Monica Mihaela, additional, Hinganu, Delia, additional, Hinganu, Marius Valeriu, additional, and Ciupilan, Corina, additional

Published
2018
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